Apparatus, method, and program

JP2026076046APending Publication Date: 2026-05-11YOKOGAWA ELECTRIC CORP
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
YOKOGAWA ELECTRIC CORP
Filing Date
2024-10-23
Publication Date
2026-05-11

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    Figure 2026076046000001_ABST
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Abstract

The present invention provides a culture apparatus, method, and program. [Solution] An apparatus is provided comprising: an acquisition unit that acquires cell information relating to cells cultured in a first culture and culture information indicating the culture conditions of the first culture; and an estimation unit that estimates the state of the culture medium after the first culture has been performed based on the cell information and the culture information, wherein the acquisition unit further acquires post-treatment information indicating the conditions of post-treatment performed on the culture medium after the first culture has been performed, and the estimation unit estimates the state of the culture medium after the first culture and post-treatment have been performed based on the cell information, the culture information and the post-treatment information.
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Claims

1. An acquisition unit that acquires cell information relating to the cells cultured in the first culture and culture information indicating the culture conditions of the first culture, An estimation unit that estimates the state of the culture medium after the first culture has been performed based on the cell information and the culture information, A device equipped with the following features.

2. The acquisition unit further acquires post-treatment information indicating the conditions for post-treatment performed on the culture medium after the first culture has been carried out. The apparatus according to claim 1, wherein the estimation unit estimates the state of the culture medium after the first culture and the post-processing have been performed, based on the cell information, the culture information, and the post-processing information.

3. The apparatus according to claim 1 or 2, wherein the state of the culture medium includes the content of at least one component contained in the culture medium.

4. The apparatus according to claim 1, wherein the estimation unit performs estimation using an estimation model that outputs state information indicating the state of the culture medium in response to the input of the cell information and culture information acquired by the acquisition unit.

5. The apparatus according to claim 4, wherein the estimation model is a trained model using training data that includes cell information relating to cultured cells, culture information indicating the culture conditions applied in the culture of said cells, and information on the state of the culture medium after said culture.

6. For each cell being cultured, there is a first memory unit that stores the predetermined initial state of the culture medium, A determination unit determines, based on the state of the culture medium estimated by the estimation unit and the contents stored by the first storage unit, at least one of the cells to be cultured in the second culture using the culture medium after the first culture, and the contents of the pretreatment to be performed on the culture medium before the start of the second culture. An output unit that outputs the decision content made by the aforementioned decision unit, The apparatus according to claim 1, further comprising:

7. The apparatus according to claim 6, wherein the determination unit determines, from among a plurality of initial states stored in the first storage unit, the cell corresponding to the initial state closest to the state of the culture medium estimated by the estimation unit, as the cell to be cultured in the second culture.

8. The apparatus according to claim 6, wherein the determination unit determines the content of the pretreatment based on the difference between the state of the culture medium estimated by the estimation unit and the initial state stored in the first storage unit in correspondence with the cells to be cultured in the second culture.

9. The system further includes a second storage unit that stores materials that can be used in the treatment solution for each type of treatment applied to the culture medium before cultivation. The apparatus according to claim 8, wherein the determination unit further determines the material to be used in the pre-treatment solution determined based on the contents stored by the second storage unit.

10. The apparatus according to claim 8, further comprising a generating unit that generates a processing liquid for the pretreatment in response to an approval operation performed by a user on the contents of the pretreatment output by the output unit.

11. The acquisition unit is, A language model unit that obtains natural language input sentences from the user, generates output sentences in natural language corresponding to those input sentences, and outputs them to the user; A specification unit that identifies the contents of the cell information and culture information from the content of the interaction with the user by the language model unit, The apparatus according to claim 1, having the following features.

12. The apparatus according to claim 11, wherein the language modeling unit asks the user questions about items from a predetermined list of items necessary for identifying the contents of the cell information and the culture information, for which information has not yet been obtained through dialogue.

13. An acquisition step is to acquire cell information relating to the cells cultured in the first culture and culture information indicating the culture conditions of the first culture. An estimation step in which the state of the culture medium after the first culture is performed is estimated based on the cell information and the culture information, A method for providing this.

14. By being executed by a computer, the computer will An acquisition unit that acquires cell information relating to the cells cultured in the first culture and culture information indicating the culture conditions of the first culture, Estimation unit that estimates the state of the culture medium after the first culture is performed, based on the cell information and culture information. A program that makes it function as such.