A method for measuring glycation of red blood cells using physical and electrical properties, a method for measuring glycated hemoglobin levels using the same, and an apparatus for performing this measurement.

A microfluidic device measures glycated hemoglobin levels by analyzing red blood cell passage time through electrode sections, addressing the limitations of existing devices for home-use glycated hemoglobin monitoring with improved accuracy and user-friendly operation.

JP2026086563APending Publication Date: 2026-05-26ORANGE BIOMED CO LTD
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
ORANGE BIOMED CO LTD
Filing Date
2026-02-04
Publication Date
2026-05-26

AI Technical Summary

Technical Problem

Existing glycated hemoglobin measuring devices are limited to hospital and laboratory settings, have short equipment lifespan, require complex storage methods, and suffer from low measurement accuracy due to user proficiency, necessitating a method for reliable home-use glycated hemoglobin measurement.

Method used

A household device using microfluidic flow path technology measures glycated hemoglobin by analyzing changes in the physical properties of red blood cells through impedance changes in a microchannel with electrode sections, calculating glycated hemoglobin levels based on passage time and user-specific reference values.

Benefits of technology

The device provides stable and accurate glycated hemoglobin measurements by minimizing external and human factor influence, enabling reliable home-use monitoring and personalized clinical decision-making.

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Abstract

We propose a method for determining the degree of glycation by measuring changes in the physical properties of glycated red blood cells. [Solution] The glycated hemoglobin measuring device 100 includes an inlet 110 through which collected blood flows in, a microchannel 130 having a predetermined width so that red blood cells in the blood flowing into the inlet pass through individually, an outlet 120 through which the red blood cells that have passed through the microchannel are discharged, and a plurality of electrode sections 140 formed in contact with the microchannel between the inlet and the outlet, the electrode sections including a plurality of electrodes connected at predetermined intervals along the direction of passage of red blood cells passing through the microchannel. The degree of hardness of glycated red blood cells can be determined more easily without chemical measuring equipment by calculating from the time it takes for them to pass through the microchannel.
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