syringe

Abstract

To provide a quantitative administration member capable of quantifying the quantity in a manner other than visual recognition.SOLUTION: A quantitative administration member includes: a plunger 107 having a protruded part on the external surface; and a flange cover 109 for covering a flange part 114 of a syringe 111, which has a hole part 116 through which the plunger is caused to pass and a concave part 125 provided on the inner surface of the hole part, through which the protruded part is caused to pass. The protruded part includes a first protruded part 115 extending in an axial direction on a front end side of the plunger, a second protruded part 117 extending in an axial direction on a rear end side of the plunger, which is disposed at a position different from the position of the first protruded part in a circumferential direction, and a continuous protruded part 119 for continuously connecting the rear end of the first protruded part and the front end of the second protruded part. When the second protruded part, the continuous protruded part, and the first protruded part pass through the inside of the concave part in this order, and the rear end of the first protruded part passes through the concave part, the plunger rotates with respect to the flange cover.SELECTED DRAWING: Figure 3

Description

[Technical field]

[0001] The present invention relates to a dosage member and a syringe. [Background technology]

[0002] There are many treatments that administer a predetermined amount of medicinal liquid, such as vaccine injections and botulinum toxin injections. General syringes are provided in volumes such as 1mL, 2mL, and 10mL, which do not necessarily match the amount of medicinal liquid required for treatment. In treatments using such syringes, the amount of medicinal liquid printed on the syringe must be visually confirmed before administration, which raises the risk of administering an incorrect amount. There are also dangerous medicinal liquids, such as botulinum toxin, that require a fixed amount to be administered, and if the amount is incorrect, it can have a negative effect not only on the affected area but also on the human body.

[0003] Therefore, Patent Document 1 discloses a syringe having an outer cylinder that can be selectively filled with liquid only when necessary to facilitate the delivery of the desired amount of liquid, a plunger that can move within the outer cylinder along the longitudinal direction of the outer cylinder and has a plurality of recesses and protrusions lined up in the longitudinal direction, and a ring-shaped mounting device that can be mounted on the outer cylinder and has protrusions that sequentially come into slidable contact with at least the protrusions as the plunger moves, and a portion that comes into contact with the plunger to regulate the rotation of the plunger relative to the outer cylinder.

[0004] However, with such syringes, the amount of medicinal liquid must be adjusted during administration, which may result in the administration of an incorrect amount.

[0005] Patent Document 2 discloses a syringe that includes an outer cylinder, a gasket that can slide inside the outer cylinder, a plunger that moves the gasket, and a stopper that is slidably installed along the longitudinal direction of the plunger, so that an accurate amount of liquid can be discharged with a simple operation; the stopper is fixed to the plunger by an engagement portion provided inside it engaging with a rack formed on the plunger; when the operating portion is pressed, this fixed state is released and the position of the stopper on the plunger can be adjusted; when the pressure on the operating portion is released, the syringe returns to its fixed state; and when the plunger is pressed toward the tip, the tip surface of the stopper abuts against the base end of the outer cylinder, thereby regulating the insertion depth of the plunger into the outer cylinder, so that a set amount of drug is discharged from the reduced diameter portion.

[0006] However, such a fixed-dose syringe has a large number of additional parts, a complex structure, and cannot be manufactured inexpensively. In addition, there are many operational procedures for the fixed dose, and it takes a long time to administer the liquid medicine. [Prior art documents] [Patent documents]

[0007] [Patent Document 1] International Publication No. 2013 / 161434 [Patent Document 2] JP 2003-199828 A Summary of the Invention [Problem to be solved by the invention]

[0008] Therefore, the present invention aims to provide a fixed-volume administration member and a syringe using the same that can perform fixed-volume administration without visual inspection and prevent administration of incorrect amounts. Another aim is to provide a fixed-volume administration member and a syringe using the same that can eliminate waste by injecting more liquid than the amount required for air removal by confirming the starting position of the plunger. Another aim is to provide a fixed-volume administration member and a syringe using the same at a low cost by modifying the plunger of a general-purpose syringe and adding a flange cover. [Means for solving the problem]

[0009] The present invention relates to a metered dose member. A plunger having a protrusion on an outer surface thereof; a flange cover that is placed over a flange portion of a syringe and has a hole portion through which the plunger passes and a recess portion provided on an inner surface of the hole portion through which the protrusion portion passes; Equipped with The protrusion includes a first protrusion extending axially toward the front end side of the plunger, a second protrusion extending axially toward the rear end side of the plunger and disposed at a position different from that of the first protrusion in the circumferential direction, and a continuous protrusion continuously connecting the rear end of the first protrusion and the front end of the second protrusion, This is a fixed-dose administration member in which the flange cover is attached to the flange portion of the syringe, the plunger is attached to the syringe, and when the plunger is pulled rearward from a state in which the second protrusion is positioned within the recess, the second protrusion, the continuous protrusion, and the first protrusion pass through the recess in that order, and when the continuous protrusion passes through the recess, the plunger rotates relative to the flange cover.

[0010] With the above-described configuration, the plunger rotates at the air bleeding position of the plunger, so that the amount of air required to be bled can be easily determined. Effect of the Invention

[0011] The present invention can provide a fixed-volume administration member and a syringe using the same that can perform fixed volume administration without visual inspection and prevent administration of incorrect amounts. It can also provide a fixed-volume administration member and a syringe using the same that can eliminate waste by injecting more liquid than the amount required for air removal by checking the plunger's fixed-volume start position. It can also provide a fixed-volume administration member and a syringe using the same at low cost by modifying the plunger of a general-purpose syringe and adding a flange cover. [Brief description of the drawings]

[0012] [Figure 1]FIG. 1 is a schematic perspective view of a syringe according to an embodiment of the present invention. [Diagram 2] FIG. 1 is a schematic exploded perspective view of a syringe according to an embodiment of the present invention. [Diagram 3] FIG. 2 is a plan view of the plunger according to the first embodiment of the present invention. [Figure 4] 4A to 4C are cross-sectional views showing respective positions of a plunger in a flange cover according to an embodiment of the present invention. [Diagram 5] 5A to 5C are diagrams illustrating the operation of a plunger according to an embodiment of the present invention. [Figure 6] FIG. 11 is a plan view of a plunger according to a second embodiment of the present invention. [Figure 7] 1 is a cross-sectional view of a syringe in which the plunger is pushed in according to an embodiment of the present invention. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0013] Various embodiments for carrying out the present invention will be described below with reference to the drawings. The metered dose administration member and syringe described below are intended to embody the technical ideas of the present disclosure, and unless otherwise specified, the present disclosure is not limited to the following. In consideration of the ease of explanation or understanding of the main points, similar members are shown with the same reference numerals in different drawings for convenience. In particular, similar effects due to similar configurations will not be mentioned in each embodiment or example. The size and positional relationship of the members shown in each drawing may be exaggerated to clarify the explanation.

[0014] (Syringe according to an embodiment of the present invention) Fig. 1 is a schematic perspective view of a syringe according to an embodiment of the present invention. Fig. 2 is a schematic exploded perspective view of a syringe according to an embodiment of the present invention. The syringe according to the embodiment of the present invention will be described with reference to Figs. 1 and 2.

[0015] 1 shows a syringe 101 according to this embodiment in a state before a needle hub with a needle attached is attached. The direction of the arrow 103 in which the needle of the syringe is located is referred to as the front end, front end side, front end direction, front end, front, etc., and the direction of the arrow 105 in which the plunger is inserted into the syringe is referred to as the rear end, rear end side, rear end direction, rear end, rear.

[0016] 2, syringe 101 according to this embodiment includes syringe 111 in which a medicinal liquid is stored, plunger 107 that is attached to syringe 111 and pushes in the medicinal liquid in syringe 111, and flange cover 109 that covers flange portion 114 of syringe 111. Flange cover 109 has hole portion 116 through which plunger 107 passes and fixes plunger 107. Gasket 113 is attached to the front end of plunger 107. Gasket 113 attached to the front end allows plunger 107 to function as a piston that pushes the medicinal liquid in syringe 111 forward without leaking.

[0017] 2, gasket 113 does not pass through hole 116 of flange cover 109, so flange cover 109 is assembled so as to be sandwiched between plunger 107 and gasket 113. In this embodiment, fixed-dose administration member 112 consisting of plunger 107 with gasket 113 attached and flange cover 109 is attached to general-purpose syringe 111 to form injector 101.

[0018] Syringe 111 is preferably made of a resin such as polypropylene. Plunger 107 is preferably made of a resin such as polypropylene or ABS. Flange cover 109 is preferably made of a resin such as polypropylene or ABS. The entire gasket is preferably made of a resin such as silicone or elastomer.

[0019] (Measuring-dose member according to the first embodiment) Fig. 3 is a plan view of the plunger according to the first embodiment. Referring to Fig. 3, a constant-dose administration member 112 according to the first embodiment of the present invention will be described.

[0020] The constant-dose administration member 112 of this embodiment includes a plunger 107, a flange cover 109, and a gasket 113. As shown in Fig. 3, the plunger 107 has protrusions 115, 117, and 119 on its outer surface. The protrusions include a first protrusion 115 extending axially toward the front end side of the plunger 107, a second protrusion 117 extending axially toward the rear end side of the plunger 107 and disposed at a different position from the first protrusion 115 in the circumferential direction, and a continuous protrusion 119 continuously connecting the rear end of the first protrusion 115 and the front end of the second protrusion 117.

[0021] The rear end of the first protrusion 115 has a surface 121 that is inclined with respect to the axial direction. The inclined surface 121 is connected to the continuous protrusion 119 like a steep ridge line in the radial direction of the axis. The continuous protrusion 119 is shorter in the circumferential direction than the first protrusion 115 and the second protrusion 117, and is formed so as to connect the first protrusion 115 and the second protrusion 117 at their overlapping portions in the circumferential direction. The continuous protrusion 119 preferably extends parallel to the axial direction.

[0022] The front end of the second protrusion 117 has a surface 123 that is substantially perpendicular (including perpendicular) to the axial direction. This surface abuts against the flange cover 109 and serves as a stopper. Therefore, it is preferable that the surface also rises steeply in the radial direction of the shaft.

[0023] (Operation of the fixed-quantity dosing component when injecting and administering the drug) Fig. 4 is a cross-sectional view of each position of the plunger in the flange cover according to the embodiment of the present invention. Fig. 5 is a diagram showing the operation of the plunger according to the embodiment of the present invention. With reference to Figs. 4 and 5, the movement of the constant-quantity administration member 112 when the plunger is pulled out of the syringe (when injecting medicinal liquid) and when the plunger is pushed in (when administering medicinal liquid) will be described.

[0024] First, plunger 107 is passed through flange cover 109, and gasket 113 is attached to prepare fixed-dose administration member 112. Then, flange portion 114 of syringe 111 is covered with flange cover 109. As shown by dotted lines in Fig. 4, flange cover 109 has hole 116 through which plunger 107 passes, and recesses 125 are provided on the inner surface of hole 116 to allow protrusions 115, 117, 119 of plunger 107 to pass through (see the lower right diagram for symbols).

[0025] Here, it is preferable that there are two recesses 125, which are point symmetrical with respect to the central axis of flange cover 109, and that there are first protrusions 115 and second protrusions 117 corresponding to the two recesses. Although one recess 125 is sufficient, it is not preferable to have three or more recesses 125 with respect to the central axis of flange cover 109, as this complicates the structure and increases costs. By providing multiple recesses 125, plunger 107 is stably fixed to flange cover 109.

[0026] In order to stabilize the position of plunger 107 within flange cover 109, it is preferable that plunger 107 has a plurality of protrusions on its outer surface, point-symmetrical with respect to the central axis of the flange cover. The height of the protrusions is preferably slightly smaller than the diameter of hole 116. If the two protrusions are offset by 90° from the two protrusions 115, 117, and 119 with respect to the central axis of flange cover 109, as in this embodiment, plunger 107 can be further stabilized.

[0027] First, the injection of the drug solution will be described. As shown in the lower right diagram of Fig. 4, the plunger 107 is fully pushed into the syringe 111, and the flange cover 109 is on the line AA. The cross section of the second protrusion 117 of the plunger 107 coincides with the recess 125 of the flange cover 109. That is, the second protrusion 117 passes through the flange cover 109.

[0028] As shown in the right middle drawing of Figure 4, when the plunger 107 is pulled out, the flange cover 109 comes to line BB. A fixed amount of liquid medicine is injected up to this point. Here, the cross section of the continuous protrusion 119 of the plunger 107 coincides with the recess 125 of the flange cover. In other words, the continuous protrusion 119 passes through the flange cover 109.

[0029] If the plunger 107 is pulled out further from this point, the flange cover 109 hits the inclined surface 121 at the rear end of the first protrusion 115, and the plunger 107 automatically rotates in the direction shown by the arrow in the middle right diagram of Figure 4. Because it rotates automatically, it is possible to tell by touch as well as by visual inspection that the plunger 107 is at the fixed position. Therefore, injection from this position can be used as a preliminary injection for removing air.

[0030] As the plunger 107 rotates from the initial position, the cross section of the first protrusion 115 coincides with the recess 125. That is, the first protrusion 115 passes through the flange cover 109. As shown in the upper right diagram of FIG. 4, the preliminary injection for air removal ends when the flange cover 109 reaches the DD line.

[0031] 5, when plunger 107 is pulled straight from a state in which second protrusion 117 is located within recess 125 during drug solution injection, second protrusion 117, continuous protrusion 119, and first protrusion 115 pass through recess 125 in this order. When inclined surface 121 at the rear end of first protrusion 115 passes through recess 125, plunger 107 rotates along inclined surface 121.

[0032] Next, air bleeding will be described. As shown in the upper left diagram of Fig. 4, when the liquid medicine is injected, the flange cover 109 is on the DD line of the plunger 107. At this time, the cross section of the first protrusion 115 of the plunger 107 coincides with the recess 125. In other words, the first protrusion 115 passes through the flange cover 109.

[0033] 4, the chemical solution is discharged until the flange cover 109 comes onto the CC line of the plunger 107, and air is removed. At this time, it can be seen that the cross section of the second protrusion 117 partially matches the recess 125 of the flange cover 109, but does not completely match, and the front end of the second protrusion 117 of the plunger abuts against the flange cover 109.

[0034] Finally, we will explain fixed-dose administration. The operator rotates the plunger in the direction of the arrow shown in the middle left diagram of Figure 4, so that second protrusion 117 is aligned with recess 125 of flange cover 109. This rotation action makes the operator aware that a fixed amount of medicinal liquid is being injected from here. Thereafter, as shown in the lower left diagram of Figure 4, second protrusion 117 passes through the recess of flange cover 109, and plunger 107 is pushed all the way into syringe 111, and flange cover 109 comes onto line AA of plunger 107.

[0035] 5, when air is bled, if plunger 107 is pushed forward with first protrusion 115 positioned within recess 125, first protrusion 115 and continuous protrusion 119 pass through the recess in this order, and the front end of second protrusion 117 comes into contact with flange cover 109. Thereafter, the operator rotates plunger 107 and pushes plunger 107 further forward, thereby injecting a fixed amount of medicinal liquid.

[0036] In this way, it is possible to provide a fixed-volume administration member and a syringe using the same that can perform a fixed amount without visual inspection and prevent administration of an incorrect amount. The present invention also provides a fixed-volume administration member and a syringe using the same that can eliminate waste by injecting more medicinal liquid than the amount required for air removal by confirming the starting position of the plunger for fixed-volume administration. The present invention also provides an inexpensive fixed-volume administration member and a syringe using the same by modifying the plunger of a general-purpose syringe and adding a flange cover.

[0037] (Second embodiment of the constant amount administration member) Fig. 6 is a plan view of a plunger according to a second embodiment of the present invention. Referring to Fig. 6, a constant-dose dispensing member 112 according to the second embodiment will be described.

[0038] A constant-dose administration member 112 according to a second embodiment of the present invention comprises a plunger 127, a flange cover 109, and a gasket 113. As shown in Fig. 6, the plunger 127 according to the second embodiment differs from the plunger of the first embodiment in that it has a third protrusion 129 whose protrusion extends axially toward the rear end side of the second protrusion 117 of the plunger 127 and is disposed at a position different from the second protrusion 117 in the circumferential direction, and a second continuous protrusion 131 which continuously connects the rear end of the second protrusion 117 and the front end of the third protrusion.

[0039] Therefore, similar to the protrusion of the plunger in the first embodiment, when flange cover 109 is attached to flange portion 114 of syringe 111, plunger 127 is attached to the syringe, and plunger 127 is pulled rearward from a state in which third protrusion 129 is positioned within recess 125, third protrusion 129, second continuous protrusion 131, and second protrusion 117 pass through the recess in that order, and when the rear end of second protrusion 117 passes through recess 125, plunger 127 rotates relative to flange cover 109.

[0040] This is because the rear end of the second protrusion 117 has a surface 133 that is inclined with respect to the axial direction. Similar to the inclined surface 121 of the first embodiment, the inclined surface 133 rises steeply like a ridge in the radial direction of the shaft and is connected to the second continuous protrusion 131. The second continuous protrusion 131 is shorter in the circumferential direction than the second protrusion 117 and the third protrusion 129, and is formed so as to connect the second protrusion 117 and the third protrusion 129 at their overlapping portions in the circumferential direction. It is preferable that the second continuous protrusion 131 extend parallel to the axial direction.

[0041] The front end of the third protrusion 129 has a surface 135 that is substantially perpendicular (including perpendicular) to the axial direction. This surface abuts against the flange cover 109 and serves as a stopper. Therefore, it is preferable that the surface be steep with respect to the radial direction of the shaft.

[0042] When plunger 127 of the second embodiment is pushed forward from a state in which third protrusion 129 is positioned within recess 125, third protrusion 129 and second continuous protrusion 131 pass through recess 125 in that order, and the front end of third protrusion 129 abuts against flange cover 109.

[0043] The fixed-volume administration member 112 of this embodiment allows multiple fixed-volume administrations; for example, 0.3 mL is administered with the second continuous protrusion 131, and another 0.3 mL is administered with the continuous protrusion 119; that is, 0.6 mL can be divided into two fixed-volume administrations. Two injections are possible with one measurement. Although two measurements are shown in this embodiment, three, four, and n-th measurements are possible by adding a fourth protrusion, a fifth protrusion, ..., and an n-th protrusion, and connecting them with a third continuous protrusion, a fourth continuous protrusion, ..., and an n-th continuous protrusion.

[0044] (Gasket according to the embodiment) Fig. 7 is a cross-sectional view of a syringe with the plunger according to the embodiment of the present invention pushed in. The gasket according to the present embodiment will be described with reference to Fig. 7.

[0045] 7, the shape of the outer surface of gasket 113 attached to the plunger according to this embodiment matches the shape of the inner surface of the tip of syringe 111. This reduces dead space and prevents a very small amount of liquid medicine, such as 0.3 mL, from being wasted.

[0046] The constant-volume administration member 112 according to the present embodiment is advantageous when injecting 0.1 mL, 0.3 mL, 0.5 mL, 2 mL, etc. of liquid medicine. It has the effect of administering a constant amount of liquid medicine and reducing dead space.

[0047] The present invention can provide a fixed-volume administration member and a syringe using the same that can perform a fixed amount without visual inspection and prevent administration of an incorrect amount. The present invention can also provide a fixed-volume administration member and a syringe using the same that can eliminate waste by injecting more medicinal liquid than the amount required for air removal by confirming the starting position of the plunger. The present invention can also provide a fixed-volume administration member and a syringe using the same at low cost by modifying the plunger of a general-purpose syringe and adding a flange cover.

[0048] Furthermore, the present invention allows multiple doses to be measured, and allows even a small amount of liquid medicine to be measured, reducing dead space.

[0049] The above-described embodiment is illustrative in all respects and is not restrictive. Modifications and changes are possible for those skilled in the art. The scope of the present invention is indicated by the claims, not the above-described embodiment. Furthermore, the scope of the present invention includes modifications from the embodiments within the scope of the claims and the equivalent scope. [Industrial Applicability]

[0050] By using the fixed-volume administration member provided by the present invention, the fixed volume can be completed without visual inspection before treatment begins, thereby providing a fixed-volume administration member and a syringe using the same that eliminate the administration of an incorrect amount after puncture. [Explanation of symbols]

[0051] 101 Syringe 103 Arrow direction at front end 105 Direction of the arrow at the rear end 107 Plunger 109 Flange cover 111 Syringe 112 Quantitative dosing component 113 Gasket 114 Flange part 115 First protrusion 116 Hole 117 Second protrusion 119 Continuous protrusion 121 Inclined Surface 123 Nearly right-angled surface 125 Recess 127 Plunger 129 Third protrusion 131 Second continuous protrusion 133 Inclined Surface 135 Nearly right-angled surface

Claims

1. A plunger having a protrusion on an outer surface thereof; a flange cover that is placed over a flange portion of a syringe and has a hole portion through which the plunger passes and a recess portion provided on an inner surface of the hole portion through which the protrusion portion passes; Equipped with The protrusion has a first protrusion extending in the axial direction toward the front end side of the plunger, a second protrusion extending in the axial direction toward the rear end side of the plunger and disposed at a position different from that of the first protrusion in the circumferential direction, and a continuous protrusion continuously connecting the rear end of the first protrusion and the front end of the second protrusion, A fixed-quantity administration member, in which the flange cover is attached to the flange portion of the syringe, the plunger is attached to the syringe, and when the plunger is pulled rearward from a state in which the second protrusion is positioned within the recess, the second protrusion, the continuous protrusion, and the first protrusion pass through the recess in that order, and when the rear end of the first protrusion passes through the recess, the plunger rotates relative to the flange cover.

2. a rear end of the first protrusion has a surface inclined with respect to an axial direction, and a front end of the second protrusion has a surface substantially perpendicular to the axial direction; 2. The quantitative dispensing member according to claim 1, wherein when the plunger is pushed forward from a state in which the first protrusion is positioned within the recess, the first protrusion and the continuous protrusion pass through the recess in that order, and the front end of the second protrusion abuts against the flange cover.

3. In order to inject a liquid drug, the plunger is inserted deep into the syringe, and is pulled until the second protrusion passes through the flange cover, the continuous protrusion passes through the flange cover while rotating the plunger, and the first protrusion passes through the flange cover; In order to bleed air, the plunger is pushed in until the front end of the second protrusion abuts against the flange cover; 3. The dispensing member of claim 2, wherein to dispense a dose, the plunger is rotated to align the second projection with the recess and to push the plunger in.

4. The two recesses are arranged point-symmetrically with respect to a central axis of the flange cover, The dispenser according to claim 1 , wherein the first protrusion and the second protrusion correspond to each of the recesses.

5. Further, the protrusion has a third protrusion extending axially toward the rear end side of the second protrusion of the plunger and disposed at a position different from the second protrusion in the circumferential direction, and a second continuous protrusion continuously connecting the rear end of the second protrusion and the front end of the third protrusion, 5. A quantitative dosing member according to claim 1, wherein when the flange cover is attached to the flange portion of the syringe, the plunger is attached to the syringe, and the plunger is pulled rearward from a state in which the third protrusion is positioned within the recess, the third protrusion, the second continuous protrusion, and the second protrusion pass through the recess in that order, and when the rear end of the second protrusion passes through the recess, the plunger rotates relative to the flange cover.

6. a rear end of the second protrusion has a surface inclined with respect to an axial direction, and a front end of the third protrusion has a surface substantially perpendicular to the axial direction; 6. The quantitative dispensing member according to claim 5, wherein when the plunger is pushed forward from a state in which the third protrusion is positioned within the recess, the third protrusion and the second continuous protrusion pass through the recess in that order, and the front end of the third protrusion abuts against the flange cover.

7. 7. The dispenser according to claim 1, wherein the outer surface of the gasket attached to the plunger matches the inner surface of the tip of the syringe.

8. 8. A dispensing member according to claim 1, wherein the dispensing member is adapted to inject between 0.1 mL and 2 mL of liquid medicine.

9. A syringe; A dispenser member according to any one of claims 1 to 8 attached to the syringe; A syringe equipped with

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