Biosensor, method for regenerating recognition molecules

The biosensor design facilitates continuous use and miniaturization by regenerating recognition molecules via pH control, addressing the limitations of conventional disposable biosensors.

JP7744039B2Active Publication Date: 2025-09-25NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY
View PDF 3 Cites 0 Cited by

Patent Information

Application Number
JP2023201854
Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
Filing Date
2023-11-29
Publication Date
2025-09-25
Estimated Expiration
2043-11-29

AI Technical Summary

Technical Problem

Conventional biosensors are disposable and cannot be used continuously due to the need for complex regeneration methods involving liquid pumps and reagents, hindering miniaturization.

Method used

A biosensor design with a flow path, electrodes, and current application means that allows pH control to dissociate biomarkers from recognition molecules, enabling continuous use without large-scale equipment.

Benefits of technology

Enables repeated use and miniaturization of biosensors by regenerating recognition molecules through controlled pH adjustment, eliminating the need for liquid pumps and reagents.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure 0007744039000001
    Figure 0007744039000001
  • Figure 0007744039000002
    Figure 0007744039000002
Patent Text Reader

Abstract

To provide a biosensor which can be repetitively and continuously used and enables further miniaturization, and to provide a method of regenerating recognition molecules in the biosensor.SOLUTION: A biosensor 1 is provided, comprising a flow channel 2 for causing a sample solution 120 containing a biomarker 110 to flow, a sensor unit 3 disposed in the flow channel 2 and provided with recognition molecules 32, a first electrode 4 and a second electrode 5 arranged at a distance from each other in the flow channel 2, current application means 6 for applying current to the first electrode 4 and the second electrode 5, and detection means 7 for detecting the biomarker 110 captured by the recognition molecules 32.SELECTED DRAWING: Figure 1
Need to check novelty before this filing date? Find Prior Art

Citation Information

Patent Citations

  • SENSOR UNIT FOR DETECTING ANALYTES, BODY FLUID MONITORING DEVICE AND METHOD - Patent application

    JP2021534930A

  • Calibration using a regenerative surface

    JP2023518112A

  • Controllable binding and dissociation of chemical entities and electrode devices therefore

    US20090205974A1