Compositions Comprising One or More (Bio)alkanediols and an Active Ingredient

1,2-Heptanediol and 2,3-heptanediol improve solubility and stability of lipophilic active ingredients in cosmetic and pharmaceutical compositions, addressing solubility and foam issues, and enhancing product clarity and safety.

JP7809116B2Active Publication Date: 2026-01-30SYMRISE GMBH & CO KG
View PDF 3 Cites 0 Cited by

Patent Information

Application Number
JP2023535316
Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
Priority Date
2020-12-09
Filing Date
2021-12-09
Publication Date
2026-01-30
Estimated Expiration
2041-12-09

AI Technical Summary

Technical Problem

Lipophilic active ingredients in cosmetic and pharmaceutical compositions have low water solubility, making it difficult to incorporate them into aqueous formulations, leading to stability and clarity issues, and existing solubilizers often cause foam formation and skin penetration problems.

Method used

Incorporating 1,2-heptanediol or 2,3-heptanediol, or a mixture of these alkanediols, to improve the solubility of lipophilic active components in cosmetic and pharmaceutical compositions, reducing the need for solubilizers and minimizing foam formation.

Benefits of technology

Enhances solubility and stability of lipophilic active ingredients, maintaining clarity and reducing foam formation, while being skin-tolerable and environmentally friendly.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure 0007809116000141
    Figure 0007809116000141
  • Figure 0007809116000142
    Figure 0007809116000142
  • Figure 0007809116000143
    Figure 0007809116000143
Patent Text Reader

Abstract

The present invention relates to cosmetic or pharmaceutical compositions, preferably dermatological compositions or home care products, comprising or consisting of a specific lipophilic active ingredient and an effective amount of 1,2-heptanediol and / or 2,3-heptanediol, or a specific alkanediol, or a mixture of two or more different specific alkanediols, and said compositions for personal care, as a medicine, or for animal care. Furthermore, the present invention relates to the use of 1,2-heptanediol and / or 2,3-heptanediol, or a specific alkanediol, or a mixture of two or more different specific alkanediols, to improve the solubility of a specific lipophilic active ingredient in a cosmetic or pharmaceutical composition. Finally, the present invention relates to the use of 1,2-heptanediol and / or 2,3-heptanediol, or a specific alkanediol, or a mixture of two or more different specific alkanediols, as a solubilizer supplement in a cosmetic or pharmaceutical composition or home care product.
Need to check novelty before this filing date? Find Prior Art

Description

[Technical Field]

[0001] The present invention relates to cosmetic, pharmaceutical, preferably dermatological, compositions or home care products comprising or consisting of a specific lipophilic active ingredient and an effective amount of 1,2-heptanediol and / or 2,3-heptanediol, or a specific alkanediol or a mixture of two or more different specific alkanediols, and the use of said compositions for cosmetics, personal care, pharmaceuticals, animal care, or home care. Furthermore, the present invention relates to the use of 1,2-heptanediol and / or 2,3-heptanediol, or a specific alkanediol or a mixture of two or more different specific alkanediols, to improve the solubility of a specific lipophilic active ingredient in a cosmetic or pharmaceutical composition. Finally, the present invention relates to the use of 1,2-heptanediol and / or 2,3-heptanediol, or a specific alkanediol or a mixture of two or more different specific alkanediols, as a solubilizer supplement in a cosmetic or pharmaceutical composition or home care product. [Background technology]

[0002] Cosmetics, personal care, dermatological pharmaceutical preparations, or home care products are complex mixtures intended for external application to the human body or for laundry, washing, and cleaning purposes. Among the long list of ingredients, lipophilic active ingredients are included. A wide range of lipophilic active ingredients are widely used in a wide range of cosmetics, personal care, or pharmaceutical preparations to fulfill various functions, such as anti-inflammatory, anti-itch, anti-redness, anti-dandruff, antimicrobial, antiperspirant, anti-cellulite, antiviral, antioxidant, anti-wrinkle, skin whitening, skin tanning, pain reduction, edema reduction, skin barrier strengthening, antifungal, anti-sagging, deodorizing, and skin soothing properties.

[0003] The drawback of these lipophilic active ingredients is their low water solubility. Due to this low water solubility, it is difficult to incorporate these ingredients into aqueous, aqueous / alcoholic, or aqueous / glycolic formulations, such as gels, liquid soaps, shampoos, gels, and even emulsions. The incorporation of these ingredients becomes even more difficult as the water content of the aqueous, aqueous / alcoholic, or aqueous / glycolic formulation increases. Due to this low water solubility, it is particularly difficult to prepare clear, non-cloudy formulations such as wet wipe solutions, micellar waters, mouthwashes, aftershaves, cleansing liquids, hair tonics, hair and body mists, facial serums, facial lotions, and deodorants.

[0004] Solubilizers are widely used to improve the solubility of lipophilic active components or ingredients in cosmetic and pharmaceutical compositions or home care products.Solubilizers are components that help solubilize or make soluble the components that are otherwise insoluble in the medium.The most suitable and most widespread use of solubilizers is to solubilize lipophilic components such as essential oils, and make them uniformly incorporated or dissolved in aqueous formulations.

[0005] Solubilizers are neither dispersants nor emulsifiers, although all three belong to the surfactant system. Emulsifiers help blend two immiscible components into an emulsion, for example, to create an O / W or W / O emulsion. The resulting emulsion usually has particle sizes in the micrometer range and appears milky white. With an emulsifier, the dispersed phase has a concentration of 1-80% (depending on the emulsifier). The two immiscible components are usually water and vegetable oil, fatty ester, wax, or fatty acid.

[0006] Solubilizer is similar to emulsifier in that it has both hydrophilic and lipophilic properties, but solubilizer is often completely water-soluble and only slightly oil-soluble.In practice, this means that they can suspend a relatively small amount of oil.When solubilizer is used, the particle size of dispersed phase is in the nanometer range, and only a small amount of lipophilic active substance is solubilized, so the whole solution may still appear transparent or thin and hazy.

[0007] Typically, essential oils, fragrance oils, or preservatives containing oil-soluble components (such as benzyl alcohol) or other lipophilic active substances are solubilized in water (or a hydrosol). The concentration of the solubilized component is typically 0.01-5.0%.

[0008] Dispersants are intermediate between solubilizers and emulsifiers. Dispersants can disperse very low concentrations of oil (such as vitamin E or triglycerides) in water. However, they do not completely solubilize the oil, so the product is not completely clear. Dispersants disperse the oil into a translucent to milky solution that remains stable for a reasonable period of time.

[0009] Aside from appearance, such formulations present safety and functionality issues. In a homogeneously solubilized product, the lipophilic active ingredient is dispersed uniformly throughout the product as very small droplets, and its concentration remains exactly the same throughout the entire solution, from the first drop to the last ml, until the bottle is completely empty. Without a solubilizer, the distribution of the lipophilic active ingredient in the solution becomes highly disordered and varies depending on the application.

[0010] Solubilizers are commonly used in aqueous formulations such as aqueous, hydroalcoholic, and hydroglycolic preparations, gels, liquid soaps, shampoos, but also in products such as bath oils, tonics, and room sprays. They are also used to stabilize suspensions and prepare colloids and gels.

[0011] However, solubilizers have various negative side effects, such as increasing foam formation.This behavior is undesirable in non-surfactant-based formulations.In most cases, they are based on ethoxylated fatty alcohols, which increase skin penetration, and therefore have negative side effects on skin.

[0012] Furthermore, the recent interest in "natural" cosmetics has refocused the attention of cosmetic chemists towards improved versions of classic ingredients or natural and renewable raw materials, i.e., sustainable raw materials.

[0013] For this reason, there remains a continuing need to provide further substances that are able to improve the solubility of lipophilic active ingredients in topical compositions and thus increase their availability in the compositions, and that do not have the above-mentioned negative aspects of commonly used solubilizers.

[0014] When searching for agents that improve solubility, it must be taken into account that substances used in the cosmetic or pharmaceutical field must be toxicologically acceptable, well tolerated by the skin, stable in particular in conventional cosmetic and / or pharmaceutical formulations, substantially and preferably odorless, and inexpensive to prepare, i.e., using standard methods.

[0015] However, the search for suitable substances is made more difficult by the lack of a clear dependency between the chemical structure of a substance on the one hand and its ability to improve solubility on the other hand. Furthermore, there is no predictable relationship between improved solubility, toxicological acceptability, tolerability and substance stability.

[0016] It is therefore an object of the present invention to provide a cosmetic or pharmaceutical composition, in particular a dermatological composition or a home care product, comprising or consisting of a lipophilic active component which has improved solubility in the cosmetic or pharmaceutical composition or home care product.

[0017] A further object of the present invention is to provide a cosmetic or pharmaceutical composition or home care product which is stable, i.e. the lipophilic active component remains solubilized and which prevents undesired crystallization or precipitation of the lipophilic active component or undesired cloudiness of the composition even when stored for extended periods of time.

[0018] Another object of the present invention is to provide substances that improve the solubility of lipophilic active ingredients in cosmetic or pharmaceutical compositions or home care products.

[0019] It is a further object of the present invention to provide substances that allow the application amount of solubilizers in cosmetic or pharmaceutical compositions or home care products to be reduced, i.e. substances that are suitable as solubilizer supplements.

[0020] It has surprisingly been found that the addition of an effective amount of 1,2-heptanediol or 2,3-heptanediol, or a mixture comprising 1,2-heptanediol and 2,3-heptanediol, or a specific alkanediol as defined herein, or a mixture of two or more different specific alkanediols, to a topical composition comprising a lipophilic active component significantly improves the solubility of said lipophilic active component.

[0021] It has been observed that the overall amount of solubilizer in a topical composition containing a lipophilic active component can be significantly reduced by adding an effective amount of 1,2-heptanediol or 2,3-heptanediol, or a mixture of 1,2-heptanediol and 2,3-heptanediol, or a specific alkanediol or a mixture of two or more different specific alkanediols as defined herein.

[0022] Furthermore, it has been found that the addition of an effective amount of 1,2-heptanediol or 2,3-heptanediol, or a mixture of 1,2-heptanediol and 2,3-heptanediol, or a specific alkanediol as defined herein, or a mixture of two or more different specific alkanediols, to a topical composition containing a lipophilic active component reduces foam formation. Summary of the Invention

[0023] In order to achieve the above object, the present invention provides, in a first aspect, (a1) 1,2-heptanediol, (b1) at least one lipophilic active component, and (c1) optionally at least one active substance and / or additive for cosmetic or pharmaceutical compositions or home care products different from the lipophilic active component (b1); or (a2) 2,3-heptanediol, (b2) at least one lipophilic active component, and (c2) optionally at least one active substance and / or additive for cosmetic or pharmaceutical compositions or home care products different from the lipophilic active component (b2); or (a3) a mixture comprising 1,2-heptanediol and 2,3-heptanediol; (b3) at least one lipophilic active component, and (c3) optionally at least one active substance and / or additive for cosmetic or pharmaceutical compositions or home care products different from the lipophilic active component (b3); The present invention provides a cosmetic or pharmaceutical composition or home care product comprising or consisting of:

[0024] In a second aspect, the present invention provides a method for producing a medicament for the treatment of a pulmonary arthritis, comprising: (a) at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or a mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols different from the first linear alkanediol having a carbon chain of 5 to 14 carbon atoms; (b) at least one lipophilic active component, and (c) optionally at least one active substance and / or additive for cosmetic or pharmaceutical compositions or home care products different from the lipophilic active component (b); The present invention provides a cosmetic or pharmaceutical composition or home care product comprising or consisting of:

[0025] In a further aspect, the present invention provides the use of a cosmetic or pharmaceutical composition as a cosmetic, for personal care, in particular for skin care, hair care, scalp care and nail care, as a pharmaceutical, for animal care or home care.

[0026] In a further aspect, the present invention provides the use of 1,2-heptanediol or 2,3-heptanediol, or a mixture comprising 1,2-heptanediol and 2,3-heptanediol, or at least one linear alkanediol, or a mixture comprising at least one first linear alkanediol and one or more second linear alkanediols, for improving the solubility of a lipophilic active component as defined herein in a cosmetic or pharmaceutical composition or home care product, and / or for increasing the availability of a lipophilic active component as defined herein, and / or for reducing foam formation in a cosmetic or pharmaceutical composition or home care product comprising a solubilizer.

[0027] In a final aspect, the present invention provides the use of 1,2-heptanediol or 2,3-heptanediol, or a mixture comprising 1,2-heptanediol and 2,3-heptanediol, or at least one linear alkanediol, or a mixture comprising at least one first linear alkanediol and one or more second linear alkanediols, as a solubilizer supplement in a cosmetic or pharmaceutical composition or a home care product. [Brief explanation of the drawings]

[0028] [Figure 1] 1 is a photograph showing the solubility of samples of bisabolol in combination with different 1,2-alkanediols.

[0029] [Figure 2] FIG. 1 is a diagram of nephelometric turbidity units of samples of bisabolol in combination with different 1,2-alkanediols.

[0030] [Figure 3] 1 is a photograph showing the solubility of samples of hydrocortisone in combination with different 1,2-alkanediols.

[0031] [Figure 4] 1 is a photograph showing the solubility of samples of ethylhexylglycerin in combination with different 1,2-alkanediols.

[0032] [Figure 5] FIG. 1 is a diagram of nephelometric turbidity units of samples of ethylhexylglycerin in combination with different 1,2-alkanediols.

[0033] [Figure 6] 1 is a photograph showing the solubility of samples of o-cymen-5-ol in combination with different 1,2-alkanediols.

[0034] [Figure 7]FIG. 1 is a diagram of nephelometric turbidity units of samples of o-cymen-5-ol in combination with different 1,2-alkanediols.

[0035] [Figure 8] 1 is a photograph showing the solubility of samples of propanediol caprylate in combination with different 1,2-alkanediols.

[0036] [Figure 9] FIG. 1 is a diagram of nephelometric turbidity units of samples of propanediol caprylate in combination with different 1,2-alkanediols.

[0037] [Figure 10] 1 is a photograph showing the solubility of samples of retinol palmitate in combination with different 1,2-alkanediols.

[0038] [Figure 11] FIG. 1 is a diagram of nephelometric turbidity units of samples of retinol palmitate in combination with different 1,2-alkanediols.

[0039] [Figure 12] 1 is a photograph showing the solubility of samples of glyceryl caprylate in combination with different 1,2-alkanediols.

[0040] [Figure 13] FIG. 1 is a diagram of nephelometric turbidity units of samples of glyceryl caprylate in combination with different 1,2-alkanediols.

[0041] [Figure 14] 1 is a photograph showing the solubility of samples of hydroxyacetophenone in combination with different 1,2-alkanediols.

[0042] [Figure 15]FIG. 1 is a diagram of nephelometric turbidity units for samples containing bisabolol and 1,2-heptanediol, 2,3-heptanediol, and a mixture containing 1,2-heptanediol and 2,3-heptanediol.

[0043] [Figure 16] FIG. 1 is a diagram of nephelometric turbidity units for samples containing ethylhexylglycerin and 1,2-heptanediol, 2,3-heptanediol, and a mixture containing 1,2-heptanediol and 2,3-heptanediol.

[0044] [Figure 17] FIG. 1 is a diagram of nephelometric turbidity units for samples containing ethylhexylglycerin and 1,2-octanediol, 2,3-octanediol, and a mixture containing 1,2-octanediol and 2,3-octanediol.

[0045] [Figure 18] FIG. 1 is a diagram of nephelometric turbidity units for samples containing propanediol caprylate and 1,2-heptanediol, 2,3-heptanediol, and a mixture containing 1,2-heptanediol and 2,3-heptanediol.

[0046] [Figure 19] FIG. 1 is a diagram of nephelometric turbidity units for samples containing propanediol caprylate and 1,2-heptanediol, 2,3-heptanediol, and a mixture containing 1,2-heptanediol and 2,3-heptanediol.

[0047] [Figure 20] 1 is a photograph showing the solubility of samples containing O-cymen-5-ol in combination with 1,2-heptanediol, 2,3-heptanediol, and a mixture containing 1,2-heptanediol and 2,3-heptanediol. DETAILED DESCRIPTION OF THE INVENTION

[0048] The invention is defined in the appended claims, but the invention itself, together with preferred modifications thereof, further objects and advantages thereof, will become apparent from the following detailed description taken in conjunction with the accompanying examples and drawings.

[0049] In a first aspect, the present invention provides a method for producing a medicament for the treatment of a pulmonary arthritis, comprising: (a1) 1,2-heptanediol, (b1) at least one lipophilic active component, and (c1) optionally at least one active substance and / or additive for cosmetic or pharmaceutical compositions or home care products different from the lipophilic active component (b1); The present invention relates to a cosmetic or pharmaceutical composition or home care product comprising or consisting of

[0050] Alternatively, in the first aspect, the present invention provides a method for producing a pharmaceutical composition comprising: (a2) 2,3-heptanediol, (b2) at least one lipophilic active component, and (c2) optionally at least one active substance and / or additive for cosmetic or pharmaceutical compositions or home care products different from the lipophilic active component (b2); The present invention relates to a cosmetic or pharmaceutical composition or home care product comprising or consisting of

[0051] In a further alternative, the present invention provides in a first aspect a method for producing a composition comprising: (a3) a mixture comprising 1,2-heptanediol and 2,3-heptanediol; (b3) at least one lipophilic active component, and (c3) optionally at least one active substance and / or additive for cosmetic or pharmaceutical compositions or home care products different from the lipophilic active component (b3); The present invention relates to a cosmetic or pharmaceutical composition or home care product comprising or consisting of

[0052] In a preferred variant of the first aspect of the invention, component (b) is different from component (a) in the three options defined above.

[0053] In a second aspect, the present invention provides a method for producing a medicament for the treatment of a pulmonary arthritis, comprising: (a) at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or a mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols different from the first linear alkanediol having a carbon chain of 5 to 14 carbon atoms; (b) at least one lipophilic active component, and (c) optionally at least one active substance and / or additive for cosmetic or pharmaceutical compositions or home care products different from the lipophilic active component (b); The present invention relates to a cosmetic or pharmaceutical composition or home care product comprising or consisting of

[0054] In a preferred variant of the second aspect of the invention, component (b) is different from component (a).

[0055] In a more preferred variation of the second aspect, the present invention provides a method for manufacturing a semiconductor device comprising: (a') a mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms, wherein the first alkanediol and the second alkanediols have the same or different numbers of carbon atoms; (b') at least one lipophilic active component, and (c') optionally at least one active substance and / or additive for cosmetic or pharmaceutical compositions or home care products different from the lipophilic active component (b); The present invention relates to a cosmetic or pharmaceutical composition or home care product comprising or consisting of

[0056] The term "comprising" means that the listed components are essential, but other components may be added and still be encompassed by the present invention.

[0057] The term "consisting of" as used in accordance with the present invention means that the total amount of components (a) to (c) is up to 100% by weight, based on the total weight of the cosmetic or pharmaceutical composition or home care product, and indicates that the subject matter is closed-ended and can include only those limitations that are expressly stated.

[0058] Whenever "comprises" is mentioned, unless the context dictates otherwise, it is intended to encompass both meanings as alternatives, i.e. the meaning may be either "comprises" or "consists of."

[0059] The term "at least one..." means that the cosmetic or pharmaceutical composition or home care product according to the present invention may contain either one of the respective components that follow the term, or a mixture of two, three, four, five, six or more different ones.

[0060] The term "optionally" means that the subsequently described compound may, but need not, be present in the composition, and that the description includes variations in which the compound is included or in which the compound is not present.

[0061] Component (a) in the cosmetic or pharmaceutical composition according to the first aspect of the present invention is either 1,2-heptanediol or 2,3-heptanediol, or a mixture of both heptanediols.

[0062] Alkanediols are any of a class of organic compounds belonging to the glycol, or alcohol, family, in which two hydroxyl (-OH) groups are attached to different carbon atoms or carbon chains.

[0063] Component (a) in the cosmetic or pharmaceutical composition or home care product according to the first aspect of the present invention is either 1,2-heptanediol (a1) or 2,3-heptanediol (a2) or a mixture containing both heptanediols, i.e. 1,2-heptanediol and 2,3-heptanediol (a3).

[0064] 1,2-heptanediol belongs to the class of alkanediols and has the general formula: [ka] It is a straight-chain alkanediol with a carbon chain containing seven carbon atoms, and the two functional OH groups of the alkanediol are in the alpha and beta positions, chemically bonded to the C1 and C2 carbon atoms of the alkanediol chain.

[0065] 2,3-Heptanediol belongs to the class of alkanediols and has the general formula: [ka] It is a straight-chain alkanediol with a carbon chain containing seven carbon atoms, and the two functional OH groups of the alkanediol are chemically bonded to the C2 and C3 carbon atoms of the alkanediol chain in the beta and gamma positions.

[0066] Linear 1,2-alkanediols have been used as multifunctional surfactants for over 15 years. Short-chain 1,2-alkanediols are amphiphilic compounds, so they are soluble in both water and cosmetic oils, such as 1,2-pentanediol and 1,2-hexanediol. In contrast, 1,2-octanediol tends to precipitate or recrystallize in oily solutions. On the other hand, 1,2-decanediol is solid and only soluble in cosmetic oils. In addition to moisturizing, some 1,2-alkanediols are used as viscosity modifiers.

[0067] Component (a) in the cosmetic or pharmaceutical composition according to the second aspect of the present invention is, in a first alternative, at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms.

[0068] Further, in a second alternative of this second aspect, component (a) can include a first linear alkanediol in combination with a second linear alkanediol, preferably at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and at least one second linear alkanediol having a carbon chain of 5 to 14 carbon atoms. Thus, the present invention also encompasses mixtures of the first and second alkanediols described herein.

[0069] Since the first linear alkanediol of the present invention can be selected from the same list and type of compounds as the linear alkanediol according to the first option of the second aspect, hereinafter, reference will be made generally to a linear alkanediol that can also be the first linear alkanediol. In a mixture of first and second linear alkanediols, the specific terms "first" and "second" are used to distinguish between the two alkanediol components, if they are particularly different.

[0070] As used herein, the phrase "at least one linear alkanediol" or "at least one first linear alkanediol" means that the composition can include one linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or can include one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or can include more than one linear alkanediol, or can include more than one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms, i.e., two, three, four or more different linear alkanediols or first linear alkanediols having a carbon chain of 5 to 14 carbon atoms.

[0071] The linear alkanediol or first linear alkanediol consists of a chain of 5 to 14 carbon atoms linked together by single covalent bonds, with two OH functional groups attached to two different carbon atoms in the chain.

[0072] The at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or the at least one first linear alkanediol, in the cosmetic or pharmaceutical composition or home care product according to the second aspect of the present invention is preferably selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, tridecanediol and tetradecanediol.

[0073] In a preferred variant, the at least one linear alkanediol or the at least one first linear alkanediol is selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol and tridecanediol.

[0074] In a more preferred variant, the at least one linear alkanediol or the at least one first linear alkanediol is selected from the group consisting of alkanediols having an odd number of carbon atoms from 5 to 13, i.e., pentanediol, heptanediol, nonanediol, undecanediol, tridecanediol and mixtures thereof.

[0075] In an even more preferred variant, the at least one linear alkanediol or the at least one first linear alkanediol is selected from the group consisting of alkanediols having an odd number of carbon atoms of 7, 9, 11 and 13, i.e., heptanediol, nonanediol, undecanediol and tridecanediol, or selected from the group consisting of alkanediols having an odd number of carbon atoms of 9 and 11, i.e., nonanediol and undecanediol, or selected from the group consisting of alkanediols having an odd number of carbon atoms of 9 and 13, i.e., nonanediol and tridecanediol, or selected from the group consisting of alkanediols having an odd number of carbon atoms of 11 and 13, i.e., undecanediol and tridecanediol.

[0076] In an even more preferred variant, the at least one linear alkanediol or the at least one first linear alkanediol is either a pentanediol, a hexanediol, a heptanediol or an octanediol.

[0077] In a most preferred variant, the at least one linear alkanediol or at least the first linear alkanediol is heptanediol.

[0078] In one alternative, the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention comprises a mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first linear alkanediol.

[0079] This means that the alkanediol mixture is a mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more, i.e., two, three, four or more, second linear alkanediols having carbon chains of 5 to 14 carbon atoms. In this alternative, the first linear alkanediol may be any of the alkanediols described herein for linear alkanediols in general, and for the first alternative of the second aspect in particular.

[0080] For example, a mixture can include one first linear alkanediol and one, two, three or more second linear alkanediols, or a mixture can include two first linear alkanediols and one, two, three or more second linear alkanediols, etc., provided that the first linear alkanediol and the second linear alkanediol in each mixture are different from each other.

[0081] The phrase "different from each other" means that the first linear alkanediol and the second linear alkanediol in the mixture differ with respect to the length of their carbon chains, i.e., the number of carbon atoms, and / or with respect to their structural isomerism or with respect to their stereoisomerism.

[0082] Similarly, the first and second linear alkanediols in the mixture may also have the same number of carbon atoms, for example, the first and second linear alkanediols have carbon chains of 7 carbon atoms, but the first and second linear alkanediols differ in terms of their constitutional isomerism or their stereoisomerism.

[0083] The second linear alkanediol preferably consists of a chain of 5 to 14 carbon atoms linked together by single covalent bonds, with two OH functional groups attached to two different carbon atoms in the chain.

[0084] The at least one second linear alkanediol having a carbon chain of 5 to 14 carbon atoms in the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention is selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, tridecanediol and tetradecanediol.

[0085] In a preferred variation, the at least one second linear alkanediol is selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, and tridecanediol. When both the first and second alkanediols are, for example, heptanediol, the second linear alkanediol, heptanediol, is a different structural or stereoisomer from the first linear alkanediol.

[0086] In a more preferred variant, the at least one second linear alkanediol is selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol and nonanediol, most preferably heptanediol, octanediol and nonanediol.

[0087] The term "alkanediol" in the context of this invention also includes its structural or positional isomers. Structural isomers are compounds with the same molecular formula but different bonding properties. Positional isomers, a specific form of structural isomerism, are structural isomers that can be considered to differ only in the position of functional groups on the parent structure, in this case the positions of the two alcohol functional groups.

[0088] Depending on the number of carbon atoms in the carbon chain of the alkanediol, there are various positional isomers of alkanediols: (x,x+1) structural isomers, (x,x+2) structural isomers, (x,x+3) structural isomers, etc., and alpha, omega structural isomers when the alcohol functional group is at the end of the carbon chain, where x represents the number of carbon atoms in the alkanediol chain to which the OH groups of the alkanediol are chemically bonded. For example, if x is 1, the two OH groups of the alkanediol are chemically bonded to the C1 and C2 carbon atoms of the alkanediol chain, if x is 2, the two OH groups of the alkanediol are chemically bonded to the C2 and C3 carbon atoms of the alkanediol chain, etc.

[0089] In the (x,x+1) structural isomer, the two OH functional groups are vicinal, meaning they are closely bonded to two different adjacent carbon atoms in the chain. In the (x,x+2) structural isomer, the two OH functional groups are bonded to two different carbon atoms in the chain, where the two carbon atoms are separated by one C atom. In the (x,x+3) structural isomer, the two OH functional groups are bonded to two different carbon atoms in the chain, where the two carbon atoms are separated by two C atoms. In the alpha,omega structural isomer, the two functional groups are bonded to the initial and terminal C atoms.

[0090] In a preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the linear alkanediol having a carbon chain of 5 to 14 carbon atoms is a vicinal (x,x+1)diol, preferably an alpha, beta 1,2 structural isomer, preferably selected from the group consisting of 1,2-diols, 2,3-diols, 3,4-diols, 4,5-diols, further (x,x+1)diols and mixtures thereof.

[0091] In a preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the first linear alkanediol and / or the second linear alkanediol having a carbon chain of 5 to 14 carbon atoms is a vicinal (x,x+1)-diol, preferably an alpha, beta 1,2 structural isomer, selected from the group consisting of 1,2-diols, 2,3-diols, 3,4-diols, 4,5-diols, further (x,x+1)-diols, and mixtures thereof.

[0092] In a further preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the linear alkanediol having a carbon chain of 5 to 14 carbon atoms is a non-vicinal (x,x+2) diol, preferably an alpha, gamma 1,3 structural isomer, preferably selected from the group consisting of 1,3-diols, 2,4-diols, 3,5-diols, further (x,x+2) diols, and mixtures thereof.

[0093] In a preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the first linear alkanediol and / or the second linear alkanediol having a carbon chain of 5 to 14 carbon atoms is a non-vicinal (x,x+2)-diol, preferably an alpha, gamma 1,3-structural isomer, selected from the group consisting of 1,3-diols, 2,4-diols, 3,5-diols, 4,6-diols, further (x,x+2)-diols, and mixtures thereof.

[0094] In a further preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the linear alkanediol having a carbon chain of 5 to 14 carbon atoms is a non-vicinal (x,x+3) diol, preferably an alpha, delta 1,4 structural isomer, preferably selected from the group consisting of 1,4 diols, 2,5 diols, further (x,x+3) diols, and mixtures thereof.

[0095] In a preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the first linear alkanediol and / or the second linear alkanediol having a carbon chain of 5 to 14 carbon atoms is a non-vicinal (x,x+3) diol, preferably an alpha,delta 1,4 structural isomer, selected from the group consisting of 1,4 diols, 2,5 diols, further (x,x+3) diols and mixtures thereof.

[0096] In a preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the linear alkanediol or the first linear alkanediol and / or the second linear alkanediol is preferably an alpha,omega alkanediol, more preferably 1,7-heptanediol or 1,8-octanediol.

[0097] According to the present invention, vicinal (x, x+1) diols such as alpha, beta or beta, gamma or gamma, delta are most preferred.

[0098] In a further preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the linear alkanediol, in particular the first linear alkanediol and / or the second linear alkanediol, is a 1,2-alkanediol, a 2,3-alkanediol, a 3,4-alkanediol or a mixture thereof, more preferably a 2,3-alkanediol.

[0099] The 1,2-alkanediol of the linear alkanediol, in particular the first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and / or the second linear alkanediol having a carbon chain of 5 to 14 carbon atoms, may preferably be represented by the following formula: 1,2-Pentanediol [ka] 1,2-Hexanediol [ka] 1,2-heptanediol [ka] 1,2-octanediol [ka] 1,2-Nonanediol [ka] 1,2-Decanediol [ka] 1,2-Undecanediol [ka] 1,2-Dodecanediol [ka] 1,2-Tridecanediol [ka] 1,2-Tetradecanediol [ka]

[0100] The 2,3-alkanediol of the linear alkanediol of the present invention, in particular the first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and / or the second linear alkanediol having a carbon chain of 5 to 14 carbon atoms, may preferably be represented by the following formula: 2,3-Pentanediol [ka] 2,3-Hexanediol [ka] 2,3-heptanediol [ka] 2,3-octanediol [ka] 2,3-Nonanediol [ka] 2,3-Decanediol [ka] 2,3-Undecanediol [ka] 2,3-Dodecanediol [ka] 2,3-Tridecanediol [ka] 2,3-Tetradecanediol [ka]

[0101] The 3,4-alkanediol of the linear alkanediol, preferably the first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and / or the second linear alkanediol having a carbon chain of 5 to 14 carbon atoms, may preferably be represented by the following formula: 3,4-Hexanediol [ka] 3,4-heptanediol [ka] 3,4-octanediol [ka] 3,4-Nonanediol [ka] 3,4-Decanediol [ka] 3,4-Undecanediol [ka] 3,4-Dodecanediol [ka] 3,4-Tridecanediol [ka] 3,4-Tetradecanediol [ka]

[0102] In a preferred variant, the cosmetic or pharmaceutical composition according to the second aspect of the invention comprises a mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms, the first and second alkanediols having the same or different number of carbon atoms.

[0103] When both the first alkanediol and the second alkanediol have the same number of carbon atoms, such a combination of alkanediols is also referred to herein as a "homoalkanediol mixture" or "homocombination." For example, the first linear alkanediol and the second linear alkanediol have carbon chains of 7 carbon atoms, but the first linear alkanediol and the second linear alkanediol differ in terms of their structural isomerism or their stereoisomerism.

[0104] When the first alkanediol and the second alkanediol have different numbers of carbon atoms, such a combination of alkanediols is also referred to herein as a "heteroalkanediol mixture" or "heterocombination." For example, the first linear alkanediol has a carbon chain of 7 carbon atoms, and the second linear alkanediol has a carbon chain of 8 carbon atoms. However, the first linear alkanediol and the second linear alkanediol may also differ in terms of their structural isomerism or their stereoisomerism.

[0105] In a preferred variant of the cosmetic or pharmaceutical composition according to the second aspect of the invention, the linear alkanediol or first linear alkanediol is selected from the group consisting of: 1,2-pentanediol, 2,3-pentanediol, 3,4-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 3,4-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-undecanediol, 2,3-undecanediol, 3,4-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 3,4-dodecanediol, 1,2-tridecanediol, 2,3-tridecanediol, 3,4-tridecanediol, and mixtures thereof.

[0106] Among the aforementioned linear alkanediols or first linear alkanediols, alpha-beta structural isomers are preferred: 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or mixtures thereof. The alkanediols are liquids with a purity of 90 to 99%.

[0107] Among the aforementioned liquid alkanediols, 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol or mixtures of said liquid alkanediols are particularly preferred, as they can be easily incorporated into semi-finished or finished products.

[0108] In a more preferred variant, the at least one linear alkanediol or the at least one first linear alkanediol is selected from the group consisting of 1,2-alkanediols having an odd number of carbon atoms from 5 to 13, i.e. 1,2-pentanediol, 1,2-heptanediol, 1,2-nonanediol, 1,2-undecanediol, 1,2-tridecanediol and mixtures thereof.

[0109] In a more preferred variant, the linear alkanediol or first linear alkanediol is selected from the group consisting of 1,2-alkanediols having an odd number of carbon atoms of 7, 9, 11 and 13, namely 1,2-heptanediol, 1,2-nonanediol, 1,2-undecanediol or 1,2-tridecanediol, or from the group consisting of 1,2-alkanediols having an odd number of carbon atoms of 9 and 11, namely 1,2-nonanediol and 1,2-undecanediol, or from the group consisting of 1,2-alkanediols having an odd number of carbon atoms of 9 and 13, namely 1,2-nonanediol and 1,2-tridecanediol, or from the group consisting of 1,2-alkanediols having an odd number of carbon atoms of 11 and 13, namely 1,2-undecanediol and 1,2-tridecanediol.

[0110] In a more preferred variant, the at least one linear alkanediol or the at least one first linear alkanediol is selected from the group consisting of 2,3-alkanediols having an odd number of carbon atoms from 5 to 13, i.e. 2,3-pentanediol, 2,3-heptanediol, 2,3-nonanediol, 2,3-undecanediol, 2,3-tridecanediol and mixtures thereof.

[0111] In an even more preferred variant, the linear alkanediol or first linear alkanediol is selected from the group consisting of 2,3-alkanediols having an odd number of carbon atoms of 7, 9, 11 and 13, namely 2,3-heptanediol, 2,3-nonanediol, 2,3-undecanediol or 2,3-tridecanediol, or selected from the group consisting of 2,3-alkanediols having an odd number of carbon atoms of 9 and 11, namely 2,3-nonanediol and 2,3-undecanediol, or selected from the group consisting of 2,3-alkanediols having an odd number of carbon atoms of 9 and 13, namely 2,3-nonanediol and 2,3-tridecanediol, or selected from the group consisting of 2,3-alkanediols having an odd number of carbon atoms of 11 and 13, namely 2,3-undecanediol and 2,3-tridecanediol.

[0112] In a further preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the linear alkanediol or first linear alkanediol is selected from the group consisting of: 1,2-pentanediol, 2,3-pentanediol, 3,4-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 3,4-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol and mixtures thereof.

[0113] More preferably, in the cosmetic or pharmaceutical composition or home care product according to the second aspect of the present invention, the linear alkanediol or first linear alkanediol is selected from the group consisting of 1,2-pentanediol, 2,3-pentanediol, 3,4-pentanediol, and mixtures thereof, or from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, and mixtures thereof, but the linear alkanediol or first linear alkanediol may also be preferably selected from the group consisting of 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, and mixtures thereof.

[0114] Even more preferably, in the cosmetic or pharmaceutical composition or home care product according to the second aspect of the present invention, the linear alkanediol or first linear alkanediol is an alpha, beta, or beta, gamma diol, such as 1,2-heptanediol, 2,3-heptanediol, or a mixture thereof. However, the linear alkanediol or first linear alkanediol may also be an alpha, beta, or beta, gamma diol, such as 1,2-octanediol, 2,3-octanediol, or a mixture thereof. Also possible are mixtures comprising 1,2-heptanediol and 2,3-octanediol, or mixtures comprising 1,2-octanediol and 2,3-heptanediol.

[0115] Most preferably, the linear alkanediol or first linear alkanediol is 1,2-heptanediol or 1,2-octanediol.

[0116] Likewise, in a further preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the linear alkanediol or first linear alkanediol is selected from the group consisting of: 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-undecanediol, 2,3-undecanediol, 3,4-undecanediol and mixtures thereof.

[0117] More preferably, in the cosmetic or pharmaceutical composition or home care product according to the second aspect of the present invention, the linear alkanediol or first linear alkanediol is selected from the group consisting of 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol and mixtures thereof, or preferably also selected from the group consisting of 1,2-decanediol, 2,3-decanediol, 3,4-decanediol and mixtures thereof, or preferably also selected from the group consisting of 1,2-undecanediol, 2,3-undecanediol, 3,4-undecanediol and mixtures thereof.

[0118] Even more preferably, in the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the linear alkanediol or first linear alkanediol is an alpha, beta or beta, gamma diol, either as 1,2-nonanediol, 2,3-nonanediol or a mixture thereof, but the linear alkanediol or first linear alkanediol may also preferably be 1,2-decanediol, 2,3-decanediol or a mixture thereof.

[0119] Furthermore, the linear alkanediol or first linear alkanediol may also preferably be 1,2-undecanediol, 2,3-undecanediol or a mixture thereof. A mixture of 1,2-nonanediol and / or 2,3-decanediol and / or 2,3-undecanediol, or a mixture of 1,2-decanediol and / or 2,3-nonanediol and / or 2,3-undecanediol, or a mixture of 1,2-undecanediol and / or 2,3-nonanediol and / or 2,3-decanediol, or a mixture of 1,2-undecanediol and / or 2,3-nonanediol and 2,3-decanediol, is also possible.

[0120] In a preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the second linear alkanediol is selected from the group consisting of: 1,2-pentanediol, 2,3-pentanediol, 3,4-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 3,4-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-undecanediol, 2,3-undecanediol, 3,4-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 3,4-dodecanediol, 1,2-tridecanediol, 2,3-tridecanediol, 3,4-tridecanediol and mixtures thereof.

[0121] Among the second linear alkanediols, the following (x, x+1) structural isomers are preferred: 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, or 2,3-tridecanediol. The alkanediols are liquids with a purity of 90 to 99%.

[0122] Among the aforementioned liquid alkanediols, 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol or mixtures of said liquid alkanediols are particularly preferred, as they can be easily incorporated into semi-finished or finished products.

[0123] In a more preferred variant, the second linear alkanediol is selected from the group consisting of 1,2-alkanediols having an odd number of carbon atoms from 5 to 13, namely 1,2-pentanediol, 1,2-heptanediol, 1,2-nonanediol, 1,2-undecanediol, 1,2-tridecanediol and mixtures thereof.

[0124] In a more preferred variant, the second linear alkanediol is selected from the group consisting of 1,2-alkanediols having an odd number of carbon atoms of 7, 9, 11 and 13, namely 1,2-heptanediol, 1,2-nonanediol, 1,2-undecanediol and 1,2-tridecanediol, or from the group consisting of 1,2-alkanediols having an odd number of carbon atoms of 9 and 11, namely 1,2-nonanediol and 1,2-undecanediol, or from the group consisting of 1,2-alkanediols having an odd number of carbon atoms of 9 and 13, namely 1,2-nonanediol and 1,2-tridecanediol, or from the group consisting of 1,2-alkanediols having an odd number of carbon atoms of 11 and 13, namely 1,2-undecanediol and 1,2-tridecanediol.

[0125] In a more preferred variant, the second linear alkanediol is selected from the group consisting of 2,3-alkanediols having an odd number of carbon atoms from 5 to 13, namely 2,3-pentanediol, 2,3-heptanediol, 2,3-nonanediol, 2,3-undecanediol, 2,3-tridecanediol and mixtures thereof.

[0126] In an even more preferred variant, the second linear alkanediol is selected from the group consisting of 2,3-alkanediols having an odd number of carbon atoms of 7, 9, 11 and 13, namely 2,3-heptanediol, 2,3-nonanediol, 2,3-undecanediol and 2,3-tridecanediol, or selected from the group consisting of 2,3-alkanediols having an odd number of carbon atoms of 9 and 11, namely 2,3-nonanediol and 2,3-undecanediol, or selected from the group consisting of 2,3-alkanediols having an odd number of carbon atoms of 9 and 13, namely 2,3-nonanediol and 2,3-tridecanediol, or selected from the group consisting of 2,3-alkanediols having an odd number of carbon atoms of 11 and 13, namely 2,3-undecanediol and 2,3-tridecanediol.

[0127] In a more preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the second linear alkanediol is selected from the group consisting of: 1,2-pentanediol, 2,3-pentanediol, 3,4-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 3,4-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol and mixtures thereof.

[0128] More preferably, in the cosmetic or pharmaceutical composition or home care product according to the second aspect of the present invention, the second linear alkanediol is selected from the group consisting of 1,2-pentanediol, 2,3-pentanediol, 3,4-pentanediol, and mixtures thereof. However, the second linear alkanediol may also be preferably selected from the group consisting of 1,2-hexanediol, 2,3-hexanediol, 3,4-hexanediol, and mixtures thereof, or preferably selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, and mixtures thereof.

[0129] Even more preferably, in the cosmetic or pharmaceutical composition or home care product according to the second aspect of the present invention, the second linear alkanediol is an alpha, beta, or beta, gamma diol, either as 1,2-pentanediol, 2,3-pentanediol, or a mixture thereof. However, the second linear alkanediol may also preferably be 1,2-hexanediol or 2,3-hexanediol, or a mixture thereof. Mixtures comprising 1,2-pentanediol and 2,3-hexanediol, or mixtures comprising 2,3-pentanediol and 1,2-hexanediol are also possible.

[0130] Most preferably, the second linear alkanediol is 1,2-pentanediol or 2,3-pentanediol, or 1,2-hexanediol or 2,3-hexanediol, or 1,2-heptanediol or 2,3-heptanediol, or 2,3-octanediol or 2,3-octanediol, or 1,2-nonanediol or 2,3-nonanediol.

[0131] In a particularly preferred variant, the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention comprising a mixture or combination comprising at least one first linear alkanediol and one or more second linear alkanediols comprises any one of the following mixtures / combinations: mixtures containing 1,2-pentanediol and 2,3-pentanediol, mixtures containing 1,2-hexanediol and 2,3-hexanediol, mixtures containing 1,2-heptanediol and 2,3-heptanediol, mixtures containing 1,2-octanediol and 2,3-octanediol, mixtures containing 1,2-nonanediol and 2,3-nonanediol, mixtures containing 1,2-decanediol and 2,3-decanediol, mixtures containing 1,2-undecanediol and 2,3-undecanediol, a mixture containing 1,2-dodecanediol and 2,3-dodecanediol, or Mixtures containing 1,2-tridecanediol and 2,3-tridecanediol.

[0132] In the homoalkanediol mixture, the first linear alkanediol and the second linear alkanediol have the same number of carbon atoms.

[0133] Particularly preferred are mixtures comprising 1,2-heptanediol in combination with 2,3-heptanediol and / or 3,4-heptanediol, or mixtures comprising 1,2-octanediol in combination with 2,3-octanediol and / or 3,4-octanediol.

[0134] The specific alkanediol mixtures according to the second aspect of the present invention, which contain either a 1,2-alkanediol or a 2,3-alkanediol having the same number of carbon atoms, are characterized by significantly improved solubility of lipophilic active components compared to the respective single 1,2-alkanediol or 2,3-alkanediol substances, which have low solubility for lipophilic active components. This effect is observed in aqueous / glycolic formulations and emulsions, even at high water contents. The lipophilic active components remain solubilized and do not crystallize or precipitate during storage, resulting in stable cosmetic or pharmaceutical formulations or home care products.

[0135] The effect or action of improving the solubility of lipophilic active components is found in homomixtures containing 1,2-pentanediol and 2,3-pentanediol, where the mixture of the alkanediol mixture with the lipophilic active component results in a clear solution, and the lipophilic component does not crystallize or precipitate during storage.

[0136] The solubility-improving effect can also be observed in homomixtures containing 1,2-hexanediol and 2,3-hexanediol. The mixtures of the alkanediol mixture and the lipophilic active component exhibit high transparency, and the lipophilic active component does not crystallize or precipitate during storage.

[0137] Homomixtures containing 1,2-heptanediol and 2,3-heptanediol are advantageous because they have a specific solubility-improving effect on lipophilic active components, and the resulting solutions of the alkanediol mixture and lipophilic active components are clear, and the lipophilic active components do not crystallize or precipitate during storage.

[0138] Alkanediol mixtures containing 1,2-octanediol and 2,3-octanediol or 1,2-nonanediol and 2,3-nonanediol are particularly advantageous because they improve the solubility of lipophilic active ingredients, and solutions of the alkanediol mixture and lipophilic active ingredient do not exhibit turbidity, and the lipophilic active ingredient does not crystallize or precipitate during storage.

[0139] Additionally, alkanediol mixtures containing 1,2-decanediol and 2,3-decanediol, or 1,2-undecanediol and 2,3-undecanediol, significantly improve the solubility of lipophilic active substances. The mixtures of alkanediol mixtures and lipophilic active components provide stable, clear solutions during storage, i.e., the lipophilic active component remains solubilized in the formulation.

[0140] The solubility-enhancing effect also applies to alkanediol mixtures containing 1,2-dodecanediol and 2,3-dodecanediol, or 1,2-tridecanediol and 2,3-tridecanediol, which mixtures of alkanediol mixtures with lipophilic active components result in clear, non-cloudy solutions in which the lipophilic active component does not precipitate during storage.

[0141] The above-identified homoalkanediol mixtures containing a 1,2-alkanediol and the corresponding 2,3-alkanediol exhibit significantly improved solubility for lipophilic active substances, clearly superior to the corresponding individual 1,2-alkanediols or 2,3-alkanediols at the same concentration but with lower solubility. Solutions of the 1,2-alkanediol and 2,3-alkanediol mixtures with lipophilic active components are all clear and stable, and the lipophilic active substances do not precipitate even during storage.

[0142] Furthermore, by blending even a small amount of a liquid 2,3-alkanediol corresponding to the solid 1,2-alkanediol, the solid 1,2-alkanediol, such as 1,2-octanediol or 1,2-nonanediol, can be dissolved to obtain a liquid alkanediol mixture. The 2,3-alkanediol functions as a solvent for the solid 1,2-alkanediol. This liquid mixture has the advantages of, first, improving the availability of the solid 1,2-alkanediol in the mixture and, second, facilitating its incorporation into semi-finished or final products. This effect is particularly advantageous for emulsions in which lipophilic 1,2-alkanediols with carbon chains of 8 or more carbon atoms tend to migrate to the oil phase or precipitate or recrystallize when used alone.

[0143] Solutions of solid 1,2-octanediol in liquid 2,3-octanediol or solid 1,2-nonanediol in liquid 2,3-nonanediol can similarly improve the availability of the 1,2-octanediol or 1,2-nonanediol in end uses.

[0144] Due to their better solubility, the availability of lipophilic active substances or components in cosmetic or pharmaceutical compositions is increased by the above-mentioned alkanediol mixtures containing 1,2-alkanediols and 2,3-alkanediols.Furthermore, due to their better solubility, lipophilic active substances may be provided at higher or lower concentrations in the final formulation compared to compositions containing lipophilic active components with lower solubility and no added alkanediol.

[0145] Due to its better solubility, lipophilic active components can be uniformly dissolved in the product, and the homogeneous solubilized product can be obtained.Therefore, the concentration of lipophilic active components is exactly the same throughout the entire formulation, from the first drop to the last ml, until the bottle is completely empty.If the alkanediol defined herein is not used, the distribution of lipophilic active components in the formulation will be very disordered and will vary depending on application.

[0146] Furthermore, the above alkanediol mixtures comprising a 1,2-alkanediol and the corresponding 2,3-alkanediol allow for the low-temperature preparation of cosmetic or pharmaceutical formulations or home care products, ie, no heating is required during preparation.

[0147] Thus, the aforementioned properties of certain alkanediol mixtures containing 1,2-alkanediols and respective 2,3-alkanediols can improve processability in formulations.

[0148] Therefore, a good compromise can be achieved by combining mixtures in a way that maintains the solubility-improving effect while improving processability in formulations. Combinations of the aforementioned 1,2-alkanediols with the corresponding 2,3-alkanediols solve this balancing problem better than either the 1,2-alkanediol or 2,3-alkanediol materials alone. This is achieved satisfactorily by combinations including 1,2-pentanediol and 2,3-pentanediol, but also by 1,2-hexanediol and 2,3-hexanediol. Combinations including 1,2-heptanediol and 2,3-heptanediol, as well as 1,2-octanediol and 2,3-octanediol, also exhibit this effect. This also applies to 1,2-nonanediol in combination with 2,3-nonanediol, as well as 1,2-decanediol in combination with 2,3-decanediol.

[0149] The homoalkanediol mixtures described above, which contain a 1,2-alkanediol and the corresponding 2,3-alkanediol, exhibit significantly synergistic activity and are clearly superior to the corresponding 1,2-alkanediol or 2,3-alkanediol individually at the same concentration.

[0150] Thus, in a particularly preferred variant, the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention comprising a mixture or combination comprising at least one first linear alkanediol and one or more second linear alkanediols comprises any one of the following mixtures / combinations: 1,2-pentanediol in combination with one of 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol, 1,2-hexanediol in combination with one of 1,2-pentanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol, 1,2-heptanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol, 1,2-octanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol, 1,2-nonanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol, 1,2-decanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol, 1,2-undecanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-dodecanediol or 1,2-tridecanediol, 1,2-dodecanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol or 1,2-tridecanediol, 1,2-tridecanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol or 1,2-dodecanediol, 2,3-pentanediol in combination with one of the following: 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol; 2,3-hexanediol in combination with one of 1,2-pentanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol, 2,3-heptanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol, 2,3-octanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol, 2,3-nonanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol, 2,3-decanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol, 2,3-undecanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-dodecanediol or 1,2-tridecanediol, 2,3-dodecanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol or 1,2-tridecanediol, or 2,3-tridecanediol in combination with one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol or 1,2-dodecanediol, 2,3-pentanediol in combination with one of 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol or 2,3-tridecanediol, 2,3-hexanediol in combination with one of 2,3-pentanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol or 2,3-tridecanediol, 2,3-heptanediol in combination with one of 2,3-pentanediol, 2,3-hexanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol or 2,3-tridecanediol, 2,3-octanediol in combination with one of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol or 2,3-tridecanediol, 2,3-nonanediol in combination with one of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol or 2,3-tridecanediol, 2,3-decanediol in combination with one of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-undecanediol, 2,3-dodecanediol or 2,3-tridecanediol, 2,3-undecanediol in combination with one of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-dodecanediol or 2,3-tridecanediol, 2,3-dodecanediol in combination with one of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol or 2,3-tridecanediol, or 2,3-Tridecanediol in combination with one of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol or 2,3-dodecanediol.

[0151] Thus, in certain preferred variants, the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, comprising a mixture or combination comprising at least one first linear alkanediol and one or more second linear alkanediols, may comprise any of the following mixtures / combinations: a mixture containing 1,2-heptanediol and 1,2-pentanediol, or a mixture containing 1,2-heptanediol and 1,2-hexanediol, or a mixture containing 1,2-heptanediol and 1,2-octanediol, or a mixture containing 1,2-heptanediol and 1,2-nonanediol, or a mixture containing 1,2-heptanediol and 1,2-decanediol, or a mixture containing 1,2-heptanediol and 1,2-undecanediol, or a mixture containing 1,2-heptanediol and 1,2-dodecanediol, or A mixture containing 1,2-heptanediol and 1,2-tridecanediol.

[0152] Thus, in certain preferred variants, the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, comprising a mixture or combination comprising at least one first linear alkanediol and one or more second linear alkanediols, may comprise any of the following mixtures / combinations: a mixture containing 1,2-heptanediol and 2,3-heptanediol, or a mixture containing 1,2-heptanediol and 2,3-pentanediol, or a mixture containing 1,2-heptanediol and 2,3-hexanediol, or a mixture containing 1,2-heptanediol and 2,3-nonanediol, or a mixture containing 1,2-heptanediol and 2,3-decanediol, or a mixture containing 1,2-heptanediol and 2,3-undecanediol, or a mixture containing 1,2-heptanediol and 2,3-dodecanediol, or A mixture containing 1,2-heptanediol and 2,3-tridecanediol.

[0153] Thus, in certain preferred variants, the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, comprising a mixture or combination comprising at least one first linear alkanediol and one or more second linear alkanediols, may comprise any of the following mixtures / combinations: mixtures containing 1,2-pentanediol and 2,3-pentanediol, mixtures containing 1,2-pentanediol and 2,3-hexanediol, mixtures containing 1,2-pentanediol and 2,3-heptanediol, mixtures containing 1,2-pentanediol and 2,3-octanediol, mixtures containing 1,2-pentanediol and 2,3-nonanediol, mixtures containing 1,2-pentanediol and 2,3-decanediol, mixtures containing 1,2-pentanediol and 2,3-undecanediol, mixtures containing 1,2-pentanediol and 2,3-dodecanediol, mixtures containing 1,2-pentanediol and 2,3-tridecanediol, mixtures containing 1,2-hexanediol and 2,3-pentanediol, mixtures containing 1,2-hexanediol and 2,3-hexanediol, mixtures containing 1,2-hexanediol and 2,3-heptanediol, mixtures containing 1,2-hexanediol and 2,3-octanediol, mixtures containing 1,2-hexanediol and 2,3-nonanediol, mixtures containing 1,2-hexanediol and 2,3-decanediol, mixtures containing 1,2-hexanediol and 2,3-undecanediol, mixtures containing 1,2-hexanediol and 2,3-dodecanediol, mixtures containing 1,2-hexanediol and 2,3-tridecanediol, mixtures containing 1,2-heptanediol and 2,3-pentanediol, mixtures containing 1,2-heptanediol and 2,3-hexanediol, mixtures containing 1,2-heptanediol and 2,3-heptanediol, mixtures containing 1,2-heptanediol and 2,3-octanediol, mixtures containing 1,2-heptanediol and 2,3-nonanediol, mixtures containing 1,2-heptanediol and 2,3-decanediol, mixtures containing 1,2-heptanediol and 2,3-undecanediol, mixtures containing 1,2-heptanediol and 2,3-dodecanediol, mixtures containing 1,2-heptanediol and 2,3-tridecanediol, mixtures containing 1,2-octanediol and 2,3-pentanediol, mixtures containing 1,2-octanediol and 2,3-hexanediol, mixtures containing 1,2-octanediol and 2,3-heptanediol, mixtures containing 1,2-octanediol and 2,3-octanediol, mixtures containing 1,2-octanediol and 2,3-nonanediol, mixtures containing 1,2-octanediol and 2,3-decanediol, mixtures containing 1,2-octanediol and 2,3-undecanediol, mixtures containing 1,2-octanediol and 2,3-dodecanediol, mixtures containing 1,2-octanediol and 2,3-tridecanediol, mixtures containing 1,2-nonanediol and 2,3-pentanediol, mixtures containing 1,2-nonanediol and 2,3-hexanediol, mixtures containing 1,2-nonanediol and 2,3-heptanediol, mixtures containing 1,2-nonanediol and 2,3-octanediol, mixtures containing 1,2-nonanediol and 2,3-nonanediol, mixtures containing 1,2-nonanediol and 2,3-decanediol, mixtures containing 1,2-nonanediol and 2,3-undecanediol, mixtures containing 1,2-nonanediol and 2,3-dodecanediol, mixtures containing 1,2-nonanediol and 2,3-tridecanediol, mixtures containing 1,2-decanediol and 2,3-pentanediol, mixtures containing 1,2-decanediol and 2,3-hexanediol, mixtures containing 1,2-decanediol and 2,3-heptanediol, mixtures containing 1,2-decanediol and 2,3-octanediol, mixtures containing 1,2-decanediol and 2,3-nonanediol, mixtures containing 1,2-decanediol and 2,3-decanediol, mixtures containing 1,2-decanediol and 2,3-undecanediol, mixtures containing 1,2-decanediol and 2,3-dodecanediol, mixtures containing 1,2-decanediol and 2,3-tridecanediol, mixtures containing 1,2-undecanediol and 2,3-pentanediol, mixtures containing 1,2-undecanediol and 2,3-hexanediol, mixtures containing 1,2-undecanediol and 2,3-heptanediol, mixtures containing 1,2-undecanediol and 2,3-octanediol, mixtures containing 1,2-undecanediol and 2,3-nonanediol, mixtures containing 1,2-undecanediol and 2,3-decanediol, mixtures containing 1,2-undecanediol and 2,3-undecanediol, mixtures containing 1,2-undecanediol and 2,3-dodecanediol, mixtures containing 1,2-undecanediol and 2,3-tridecanediol, mixtures containing 1,2-dodecanediol and 2,3-pentanediol, mixtures containing 1,2-dodecanediol and 2,3-hexanediol, mixtures containing 1,2-dodecanediol and 2,3-heptanediol, mixtures containing 1,2-dodecanediol and 2,3-octanediol, mixtures containing 1,2-dodecanediol and 2,3-nonanediol, mixtures containing 1,2-dodecanediol and 2,3-decanediol, mixtures containing 1,2-dodecanediol and 2,3-undecanediol, a mixture containing 1,2-dodecanediol and 2,3-dodecanediol, or A mixture containing 1,2-dodecanediol and 2,3-tridecanediol.

[0154] Thus, in certain preferred variants, the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, comprising a mixture or combination comprising at least one first linear alkanediol and one or more second linear alkanediols, may comprise any of the following mixtures / combinations: mixtures containing 2,3-pentanediol and 2,3-hexanediol, mixtures containing 2,3-pentanediol and 2,3-heptanediol, mixtures containing 2,3-pentanediol and 2,3-octanediol, mixtures containing 2,3-pentanediol and 2,3-nonanediol, mixtures containing 2,3-pentanediol and 2,3-decanediol, mixtures containing 2,3-pentanediol and 2,3-undecanediol, mixtures containing 2,3-pentanediol and 2,3-dodecanediol, mixtures containing 2,3-pentanediol and 2,3-tridecanediol, mixtures containing 2,3-hexanediol and 2,3-pentanediol, mixtures containing 2,3-hexanediol and 2,3-heptanediol, mixtures containing 2,3-hexanediol and 2,3-octanediol, mixtures containing 2,3-hexanediol and 2,3-nonanediol, mixtures containing 2,3-hexanediol and 2,3-decanediol, mixtures containing 2,3-hexanediol and 2,3-undecanediol, mixtures containing 2,3-hexanediol and 2,3-dodecanediol, mixtures containing 2,3-hexanediol and 2,3-tridecanediol, mixtures containing 2,3-heptanediol and 2,3-pentanediol, mixtures containing 2,3-heptanediol and 2,3-hexanediol, mixtures containing 2,3-heptanediol and 2,3-octanediol, mixtures containing 2,3-heptanediol and 2,3-nonanediol, mixtures containing 2,3-heptanediol and 2,3-decanediol, mixtures containing 2,3-heptanediol and 2,3-undecanediol, mixtures containing 2,3-heptanediol and 2,3-dodecanediol, mixtures containing 2,3-heptanediol and 2,3-tridecanediol, mixtures containing 2,3-octanediol and 2,3-pentanediol, mixtures containing 2,3-octanediol and 2,3-hexanediol, mixtures containing 2,3-octanediol and 2,3-heptanediol, mixtures containing 2,3-octanediol and 2,3-nonanediol, mixtures containing 2,3-octanediol and 2,3-decanediol, mixtures containing 2,3-octanediol and 2,3-undecanediol, mixtures containing 2,3-octanediol and 2,3-dodecanediol, mixtures containing 2,3-octanediol and 2,3-tridecanediol, mixtures containing 2,3-nonanediol and 2,3-pentanediol, mixtures containing 2,3-nonanediol and 2,3-hexanediol, mixtures containing 2,3-nonanediol and 2,3-heptanediol, mixtures containing 2,3-nonanediol and 2,3-octanediol, mixtures containing 2,3-nonanediol and 2,3-decanediol, mixtures containing 2,3-nonanediol and 2,3-undecanediol, mixtures containing 2,3-nonanediol and 2,3-dodecanediol, mixtures containing 2,3-nonanediol and 2,3-tridecanediol, mixtures containing 2,3-decanediol and 2,3-pentanediol, mixtures containing 2,3-decanediol and 2,3-hexanediol, mixtures containing 2,3-decanediol and 2,3-heptanediol, mixtures containing 2,3-decanediol and 2,3-octanediol, mixtures containing 2,3-decanediol and 2,3-nonanediol, mixtures containing 2,3-decanediol and 2,3-undecanediol, mixtures containing 2,3-decanediol and 2,3-dodecanediol, mixtures containing 2,3-decanediol and 2,3-tridecanediol, mixtures containing 2,3-undecanediol and 2,3-pentanediol, mixtures containing 2,3-undecanediol and 2,3-hexanediol, mixtures containing 2,3-undecanediol and 2,3-heptanediol, mixtures containing 2,3-undecanediol and 2,3-octanediol, mixtures containing 2,3-undecanediol and 2,3-nonanediol, mixtures containing 2,3-undecanediol and 2,3-decanediol, mixtures containing 2,3-undecanediol and 2,3-dodecanediol, mixtures containing 2,3-undecanediol and 2,3-tridecanediol, mixtures containing 2,3-dodecanediol and 2,3-pentanediol, mixtures containing 2,3-dodecanediol and 2,3-hexanediol, mixtures containing 2,3-dodecanediol and 2,3-heptanediol, mixtures containing 2,3-dodecanediol and 2,3-octanediol, mixtures containing 2,3-dodecanediol and 2,3-nonanediol, mixtures containing 2,3-dodecanediol and 2,3-decanediol, 2,3-dodecanediol and mixtures containing 2,3-dodecanediol, A mixture containing 2,3-dodecanediol and 2,3-tridecanediol.

[0155] Particularly preferred are mixtures comprising 2,3-hexanediol and 2,3-heptanediol, or mixtures comprising 2,3-hexanediol and 2,3-octanediol, or mixtures of 2,3-heptanediol and 2,3-octanediol.

[0156] In the heteroalkanediol mixture described above, the first linear alkanediol and the second linear alkanediol have different numbers of carbon atoms.

[0157] The above-described alkanediol mixtures according to the second aspect of the present invention, comprising 1,2-alkanediols and 2,3-alkanediols, are characterized by significantly improved solubility of lipophilic active components compared to the respective individual 1,2-alkanediol or 2,3-alkanediol substances, which have only low solubility in lipophilic active components. This effect is observed in aqueous / glycolic formulations and emulsions, even at high water contents. The lipophilic active components remain solubilized and do not crystallize or precipitate during storage, resulting in stable cosmetic or pharmaceutical formulations or home care products.

[0158] Of the above-mentioned alkanediol mixtures or combinations comprising at least one first linear alkanediol and one or more second linear alkanediols according to the second aspect of the invention, particularly preferred are heteromixtures or combinations of alkanediols according to the second aspect of the invention comprising 1,2-hexanediol and 2,3-octanediol, or mixtures or combinations of alkanediols comprising 2,3-octanediol and 2,3-hexanediol, or mixtures or combinations of alkanediols comprising 1,2-octanediol and 2,3-heptanediol.

[0159] These particular heteroalkanediol mixtures according to the second aspect of the invention exhibit a synergistically enhanced effect, i.e., they improve the solubility of lipophilic active ingredients in cosmetic or pharmaceutical preparations or home care products compared to their corresponding single 1,2-alkanediol or 2,3-alkanediol substances, i.e., 1,2-hexanediol or 1,2-octanediol or 2,3-octanediol or 2,3-hexanediol or 2,3-heptanediol, resulting in clear, non-cloudy formulations.

[0160] The alkanediol mixture containing 1,2-hexanediol and 2,3-octanediol improves the solubility of lipophilic active substances, and the mixture of the alkanediol mixture and lipophilic active substance exhibits high transparency and does not crystallize or precipitate out of the lipophilic active component even during storage.

[0161] The solubility-improving effect can also be observed in heteromixtures containing 1,2-octanediol and 2,3-hexanediol. The resulting mixtures of the alkanediol mixture and lipophilic active substances are clear and transparent, and the lipophilic active components do not crystallize or precipitate even during storage.

[0162] The solubility-improving effect on lipophilic active substances can also be observed in heteroalkanediol mixtures containing 1,2-octanediol and 2,3-heptanediol.

[0163] The above mixtures are evident in aqueous / glycolic formulations, even at high water contents, as well as emulsions.

[0164] Furthermore, by blending solid 1,2-octanediol with 2,3-hexanediol or 2,3-heptanediol, the solid 1,2-octanediol is dissolved, resulting in a liquid alkanediol mixture. The 2,3-hexanediol or 2,3-heptanediol acts as a solvent for the solid 1,2-octanediol. This liquid mixture has the advantages of, first, improving the availability of the 1,2-octanediol in the mixture and, second, facilitating its incorporation into semi-finished or final products. This effect is particularly advantageous for emulsions where lipophilic 1,2-alkanediols with carbon chains of 8 or more carbon atoms tend to migrate to the oil phase or recrystallize or precipitate when used alone.

[0165] Furthermore, a clear improvement in solubility can be observed in alkanediol mixtures or combinations as defined below comprising at least one first linear alkanediol and one or more second linear alkanediols according to the second aspect of the invention, namely mixtures of alkanediols comprising 1,2-pentanediol and 2,3-hexanediol, or mixtures comprising 1,2-pentanediol and 1,2-heptanediol, or mixtures comprising 1,2-pentanediol and 2,3-heptanediol, or mixtures comprising 1,2-pentanediol and 2,3-octanediol, or mixtures comprising 1,2-pentanediol and 1,2-nonanediol, or mixtures comprising 1,2-pentanediol and 2,3-nonanediol.

[0166] The above-mentioned heteroalkanediol mixtures containing 1,2-alkanediols and 2,3-alkanediols significantly improve the solubility of lipophilic active substances, resulting in clear solutions, which are significantly superior to the corresponding individual 1,2-alkanediols or 2,3-alkanediols.

[0167] The alkanediol mixture containing 1,2-pentanediol and 2,3-hexanediol clearly improves the solubility of lipophilic active ingredients, and the resulting solution of the alkanediol mixture and lipophilic active ingredient is clear, and the lipophilic active ingredient does not crystallize or precipitate during storage.

[0168] Additionally, the alkanediol mixture containing 1,2-pentanediol and 1,2-heptanediol synergistically improves the solubility of lipophilic active ingredients. The resulting solution does not exhibit turbidity, i.e., crystallization, and is stable during storage.

[0169] The solubility-improving effect can also be observed with alkanediol mixtures containing 1,2-pentanediol and 2,3-heptanediol. Similarly, with alkanediol mixtures containing 1,2-pentanediol and 2,3-octanediol. The resulting solutions of the alkanediol mixtures and lipophilic active ingredients are clear, without crystallization or precipitation, even during storage.

[0170] In addition, alkanediol mixtures containing 1,2-pentanediol and 1,2-nonanediol, or 1,2-pentanediol and 2,3-nonanediol, are effective in improving the solubility of lipophilic active ingredients, resulting in stable formulations, i.e., formulations in which the lipophilic active ingredient remains solubilized and storage of the mixture does not result in undesired crystallization or precipitation of the lipophilic active ingredient.

[0171] Improved solubility of lipophilic active components can significantly improve the shelf life of cosmetic or pharmaceutical preparations or home care products containing such alkanediol / lipophilic active component mixtures.

[0172] Furthermore, significant improvements in the solubility of lipophilic active ingredients can also be observed in heteroalkanediol mixtures, i.e., mixtures of alkanediols comprising 1,2-heptanediol and 1,2-octanediol, or mixtures of alkanediols comprising 1,2-heptanediol and 2,3-octanediol, or mixtures of alkanediols comprising 1,2-heptanediol and 1,2-nonanediol, or mixtures or combinations of alkanediols comprising 1,2-heptanediol and 2,3-nonanediol.

[0173] In particular, an alkanediol mixture containing 1,2-heptanediol and 1,2-octanediol, or an alkanediol mixture containing 1,2-heptanediol and 2,3-octanediol, has a significant effect of improving the solubility of lipophilic active components, and no or little recrystallization or precipitation of the lipophilic active components can be observed even during storage.

[0174] Good solubility of lipophilic active ingredients can be observed not only with alkanediol mixtures containing 1,2-heptanediol and 1,2-nonanediol, but also with alkanediol mixtures containing 1,2-heptanediol and 2,3-nonanediol, both of which are effective in better solubilizing lipophilic active ingredients, resulting in clear, non-cloudy formulations that remain free of undesired crystallization or precipitation of the lipophilic active ingredients even during storage.

[0175] The heteroalkanediol mixtures described above exhibit significantly improved solubility of lipophilic active substances, clearly superior to the corresponding 1,2-alkanediols or 2,3-alkanediols at the same concentration but with lower solubility. Solutions of the heteroalkanediol mixtures with lipophilic active components are all clear and stable, and the lipophilic active substances do not precipitate even during storage.

[0176] As a result, by improving the solubility of lipophilic active substances, the storage stability and thus the shelf life of cosmetic or pharmaceutical preparations or home care products can be significantly extended.

[0177] Due to its better solubility, the availability of lipophilic active substances or components in cosmetic or pharmaceutical compositions is increased. Furthermore, due to its better solubility, the lipophilic active substances may be provided at higher concentrations in the final formulation or at lower concentrations in the final formulation compared to compositions containing lipophilic active components that are less soluble and do not have an alkanediol added.

[0178] Due to its better solubility, lipophilic active components can be uniformly dissolved in the product, and the homogeneous solubilized product can be obtained.Therefore, the concentration of lipophilic active components is exactly the same throughout the entire formulation, from the first drop to the last ml, until the bottle is completely empty.If the alkanediol defined herein is not used, the distribution of lipophilic active components in the formulation will be very disordered and will vary depending on application.

[0179] Furthermore, the heteroalkanediol mixture containing 2,3-alkanediol allows for the low-temperature preparation of cosmetic or pharmaceutical formulations or home care products, i.e., no heating is required during preparation, thereby improving the processability of the formulations.

[0180] Therefore, a good compromise can be achieved by combining active mixtures in a manner that improves solubility for lipophilic active components while improving processability in formulations. The above-described alkanediol combinations, including a first linear alkanediol and a second linear alkanediol, solve this balancing problem better than each of the 1,2-alkanediol or 2,3-alkanediol materials alone.

[0181] As a result, improving the solubility of lipophilic active substances can significantly improve the storage stability and shelf life of cosmetic or pharmaceutical preparations or home care products.

[0182] In a preferred variant according to the second aspect of the invention in a cosmetic or pharmaceutical composition or home care product, the linear alkanediol is selected from the group consisting of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol and mixtures thereof.

[0183] In a more preferred variant of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention, the linear alkanediol is selected from the group consisting of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol and mixtures thereof.

[0184] Surprisingly, the addition of other 2,3-alkanediols, such as 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, as well as 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, and 2,3-tridecanediol, improves the solubility of lipophilic active substances, resulting in less or no precipitation or crystallization during storage.

[0185] As mentioned above, by using 2,3-alacanediol to improve the solubility of lipophilic active substances, stable formulations can be obtained, significantly improving the shelf life of cosmetic or pharmaceutical preparations or home care products.

[0186] Furthermore, the above-mentioned 2,3-alkanediols have the advantage of being liquid, which may facilitate their incorporation into semi-finished or finished products and may improve their availability in said products. Furthermore, in emulsions, the 2,3-alkanediols remain in the aqueous phase and can exert their antimicrobial activity directly where microbial contamination occurs, without tending to migrate to the oil phase.

[0187] Therefore, a good compromise can be achieved by combining the active 2,3-alkanediol / lipophilic active mixture in a manner that improves the solubility of the lipophilic active while improving processability in the formulation. The 2,3-alkanediols described above solve this balancing problem better than solid 1,2-alkanediol materials.

[0188] In a particularly advantageous variant according to the second aspect of the invention, the linear alkanediol or the first alkanediol or the second alkanediol is a liquid alkanediol.

[0189] The term "liquid alkanediol" in the context of the present invention means an alkanediol component that is liquid at room or ambient temperature and normal pressure, i.e., under standard RTP conditions.

[0190] In a highly preferred variant according to the second aspect of the invention, the linear alkanediol or the first alkanediol or the second alkanediol is a liquid alkanediol selected from the group consisting of 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol and mixtures thereof.

[0191] Of the aforementioned alkanediols, 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol or mixtures thereof are most preferred.

[0192] In a particularly advantageous variant according to the second aspect of the invention, the linear alkanediol or the first alkanediol or the second alkanediol is characterized in that it has a maximum water solubility of 10% by weight or less. In a preferred variant, the maximum water solubility of the linear alkanediol or the first alkanediol or the second alkanediol is 10% by weight or less and 1.2% by weight or more. More preferably, the maximum water solubility of the linear alkanediol or the first linear alkanediol or the second linear alkanediol is 5% by weight or less and 1.4% by weight or more.

[0193] Preferably, the water-soluble alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 2,3-octanediol, and mixtures thereof.

[0194] The water solubility of a substance is the saturated mass concentration of the substance in water at a given temperature. The determination of water solubility refers to essentially pure substances that are stable and non-volatile in water. The determination of the water solubility of alkanediols is further described in Example 2 below.

[0195] The term "alkanediol" in the context of the present invention also includes its stereoisomers. Stereoisomers are molecules that have the same molecular formula and differ only in how their atoms are arranged in three-dimensional space. In accordance with the above definition, the linear alkanediols of the present invention, and the first alkanediol having a carbon chain of 5 to 14 carbon atoms or the second linear alkanediol having a carbon chain of 5 to 14 carbon atoms described in detail above, encompass the following stereoisomers:

[0196] Stereoisomers of 1,2-alkanediols: (2S)-pentane-1,2-diol, (2S)-hexane-1,2-diol, (2S)-heptane-1,2-diol, (2S)-octane-1,2-diol, (2S)-nonane-1,2-diol, (2S)-decane-1,2-diol, (2S)-undecane-1,2-diol, (2S)-dodecane-1,2-diol, (2S)-tridecane-1,2-diol, (2S)-tetradecane-1,2-diol, (2R)-pentane-1,2-diol, (2R)-hexane-1,2-diol, (2R)-heptane-1,2-diol, (2R)-octane-1,2-diol, (2R)-nonane-1,2-diol, (2R)-decane-1,2-diol, (2R)-undecane-1,2-diol, (2R)-dodecane-1,2-diol, (2R)-tridecane-1,2-diol, (2R)-tetradecane-1,2-diol,

[0197] Stereoisomers of 2,3-alkanediols: (2S,3S)-pentane-2,3-diol, (2S,3S)-hexane-2,3-diol, (2S,3S)-heptane-2,3-diol, (2S,3S)-octane-2,3-diol, (2S,3S)-nonane-2,3-diol, (2S,3S)-decane-2,3-diol, (2S,3S)-undecane-2,3-diol, (2S,3S)-dodecane-2,3-diol, (2S,3S)-tridecane-2,3-diol, (2S,3S)-tetradecane-2,3-diol, (2R,3R)-pentane-2,3-diol, (2R,3R)-hexane-2,3-diol, (2R,3R)-heptane-2,3-diol, (2R,3R)-octane-2,3-diol, (2R,3R)-nonane-2,3-diol, (2R,3R)-decane-2,3-diol, (2R,3R)-undecane-2,3-diol, (2R,3R)-dodecane-2,3-diol, (2R,3R)-tridecane-2,3-diol, (2R,3R)-tetradecane-2,3-diol, (2S,3R)-pentane-2,3-diol, (2S,3R)-hexane-2,3-diol, (2S,3R)-heptane-2,3-diol, (2S,3R)-octane-2,3-diol, (2S,3R)-nonane-2,3-diol, (2S,3R)-decane-2,3-diol, (2S,3R)-undecane-2,3-diol, (2S,3R)-dodecane-2,3-diol, (2S,3R)-tridecane-2,3-diol, (2S,3R)-tetradecane-2,3-diol, (2R,3S)-pentane-2,3-diol, (2R,3S)-hexane-2,3-diol, (2R,3S)-heptane-2,3-diol, (2R,3S)-octane-2,3-diol, (2R,3S)-nonane-2,3-diol, (2R,3S)-decane-2,3-diol, (2R,3S)-undecane-2,3-diol, (2R,3S)-dodecane-2,3-diol, (2R,3S)-tridecane-2,3-diol, and (2R,3S)-Tetradecane-2,3-diol.

[0198] Stereoisomers of 3,4-alkanediols: (3R,4R)-hexane-3,4-diol, (3R,4R)-heptane-3,4-diol, (3R,4R)-octane-3,4-diol, (3R,4R)-nonane-3,4-diol, (3R,4R)-decane-3,4-diol, (3R,4R)-undecane-3,4-diol, (3R,4R)-dodecane-3,4-diol, (3R,4R)-tridecane-3,4-diol, (3R,4R)-tetradecane-3,4-diol, (3S,4S)-hexane-3,4-diol, (3S,4S)-heptane-3,4-diol, (3S,4S)-octane-3,4-diol, (3S,4S)-nonane-3,4-diol, (3S,4S)-decane-3,4-diol, (3S,4S)-undecane-3,4-diol, (3S,4S)-dodecane-3,4-diol, (3S,4S)-tridecane-3,4-diol, (3S,4S)-tetradecane-3,4-diol, (3R,4S)-hexane-3,4-diol, (3R,4S)-heptane-3,4-diol, (3R,4S)-octane-3,4-diol, (3R,4S)-nonane-3,4-diol, (3R,4S)-decane-3,4-diol, (3R,4S)-undecane-3,4-diol, (3R,4S)-dodecane-3,4-diol, (3R,4S)-tridecane-3,4-diol, (3R,4S)-tetradecane-3,4-diol, (3S,4R)-hexane-3,4-diol, (3S,4R)-heptane-3,4-diol, (3S,4R)-octane-3,4-diol, (3S,4R)-nonane-3,4-diol, (3S,4R)-decane-3,4-diol, (3S,4R)-undecane-3,4-diol, (3S,4R)-dodecane-3,4-diol, (3S,4R)-tridecane-3,4-diol, and (3S,4R)-Tetradecane-3,4-diol.

[0199] In the context of this document, the terms "1,2-diol", "2,3-diol" or "3,4-diol" include both the corresponding S-configured enantiomers as well as the R-enantiomers, as well as any mixture of these S- and R-configured enantiomers, i.e., racemic mixtures of the respective diols.

[0200] The alkanediol mixture of the cosmetic or pharmaceutical composition or home care product according to the first aspect of the present invention comprises 1,2-heptanediol and 2,3-heptanediol in a ratio in the range of 50:50 to 99.9:0.1, preferably in a ratio in the range of 75:25 to 99:1, more preferably in a ratio in the range of 80:20 to 98:2, and even more preferably in a ratio in the range of 90:10 to 95:5.

[0201] In the cosmetic or pharmaceutical composition according to the first aspect of the present invention, 1,2-heptanediol and 2,3-heptanediol are preferably contained in the mixture in a ratio ranging from 98:2 to 99.9:0.1.

[0202] In the home care product according to the first aspect of the invention, 1,2-heptanediol and 2,3-heptanediol are preferably contained in the alkanediol mixture in a ratio ranging from 95:5 to 99.9:0.1.

[0203] Preferably, 1,2-heptanediol and 2,3-heptanediol are present in the cosmetic or pharmaceutical composition or home care product mixture according to the first aspect of the invention in a ratio of ≧95:≦5, more preferably in a ratio of ≧96:≦4, even more preferably in a ratio of ≧97:≦3, and most preferably in a ratio of ≧98:≦2.

[0204] Most of all mixtures of cosmetic or pharmaceutical compositions or home care products according to the first aspect of the invention contain 1,2-heptanediol and 2,3-heptanediol in a ratio of ≧95:≦5, including ratios of ≧95.5:≦4.5, ≧96:≦4, ≧96.5:≦3.5, ≧97:≦3, ≧97.5:2.5 and ≧98.0:≦2.0.

[0205] Even more preferably, the alkanediol mixture of the cosmetic or pharmaceutical composition or home care product according to the first aspect of the invention comprises 1,2-heptanediol and 2,3-heptanediol in a ratio of ≥98:≤2, such as ≥98.1:≤1.9, ≥98.2:≤1.8, ≥98.3:≤1.7, ≥98.4:≤1.6, ≥98.5:≤1.5, ≥98.6:≤1.6, ≥98.7:≤1.7, ≥98.8:≤1.8, ≥98.9:≤1.9, ≥98.10:≤1.9, ≥98.11:≤1.9, ≥98.22:≤1.8, ≥98.33:≤1.7, ≥98.44:≤1.6, ≥98.55:≤1.5, ≥98.66:≤1.8, ≥98.77:≤1.8, ≥98.88:≤1.8, ≥98.99:≤1.8, ≥98.109:≤1.9, ≥98.111:≤1.9, ≥98.12:≤1.9, ≥98.13:≤1.9, ≥98.14:≤1.9, ≥98.15:≤1.9, ≥98.16:≤1.9, ≥98.17:≤1.9, ≥98.18:≤1.9, ≥98.19:≤1.9, ≥98.20:≤1.8, ≥98.21:≤1.8, ≥98.22:≤1.8, ≥98.23:≤1.8, ≥98.24:≤1.8, ≥98.25:≤1. These include ratios of 6:≦1.4, ≧98.7:≦1.3, ≧98.8:≦1.2, ≧98.9:≦1.1, ≧99:≦1.0, ≧99.1:≦0.9, ≧99.2:≦0.8, ≧99.3:≦0.7, ≧99.4:≦0.6, ≧99.5:≦0.5, ≧99.6:≦0.4, ≧99.7:≦0.3, ≧99.8:≦0.2 and ≧99.9:≦0.1.

[0206] The first linear alkanediol and the second linear alkanediol as defined in detail above are present in the alkanediol mixture according to the second aspect of the invention in a ratio ranging from 50:50 to 99.9:0.1, preferably in a ratio ranging from 75:25 to 99:1, more preferably in a ratio ranging from 80:20 to 98:2, and even more preferably in a ratio ranging from 90:10 to 95:5.

[0207] In the cosmetic or pharmaceutical preparation according to the second aspect of the invention, the first linear alkanediol and the second linear alkanediol are preferably contained in the mixture in a ratio ranging from 98:2 to 99.9:0.1.

[0208] In the home care product according to the second aspect of the present invention, the first linear alkanediol and the second alkanediol are preferably contained in the alkanediol mixture in a ratio ranging from 95:5 to 99.9:0.1.

[0209] Preferably, the first linear alkanediol and the second alkanediol are present in the cosmetic or pharmaceutical composition or home care product mixture according to the second aspect of the present invention in a ratio in the range of ≧95:≦5, more preferably in a ratio of ≧96:≦4, even more preferably in a ratio of ≧97:≦3, and most preferably in a ratio of ≧98:≦2.

[0210] Most of all mixtures of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention comprise a first linear alkanediol and a second linear alkanediol in a ratio of ≧95:≦5, including ratios of ≧95.5:≦4.5, ≧96:≦4, ≧96.5:≦3.5, ≧97:≦3, ≧97.5:2.5 and ≧98.0:≦2.0.

[0211] Even more preferably, the alkanediol mixture of the cosmetic or pharmaceutical composition or home care product according to the second aspect of the invention comprises a first linear alkanediol and a second alkanediol in a ratio in the range of ≧98:≦2, with the following ranges being possible: ≧98.1:≦1.9, ≧98.2:≦1.8, ≧98.3:≦1.7, ≧98.4:≦1.6, ≧98.5:≦1.5, ≧98.6:≦1.6, ≧98.7:≦1.6, ≧98.8:≦1.6, ≧98.9:≦1.6, ≧98.10:≦1.6, ≧98.11:≦1.6, ≧98.12:≦1.6, ≧98.13:≦1.6, ≧98.14:≦1.6, ≧98.15:≦1.6, ≧98.16:≦1.6, ≧98.17:≦1.6, ≧98.18:≦1.6, ≧98.19 ... These include ratios of 8.6:≦1.4, ≧98.7:≦1.3, ≧98.8:≦1.2, ≧98.9:≦1.1, ≧99:≦1.0, ≧99.1:≦0.9, ≧99.2:≦0.8, ≧99.3:≦0.7, ≧99.4:≦0.6, ≧99.5:≦0.5, ≧99.6:≦0.4, ≧99.7:≦0.3, ≧99.8:≦0.2 and ≧99.9:≦0.1.

[0212] Alternatively, the above ratio ranges for the first and second alkanediols are reversed so that the second alkanediol is the major component and the first alkanediol is the minor component.

[0213] In an advantageous variant according to the second aspect of the invention, the mixture comprises as the first linear alkanediol a 1,2-alkanediol, such as 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol, and as the second linear alkanediol a corresponding 2,3-alkanediol, such as For example, 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol or 2,3-tridecanediol in a ratio ranging from 50:50 to 99.9:0.1, preferably in a ratio ranging from 75:25 to 99:1, more preferably in a ratio ranging from 80:20 to 98:2, and even more preferably in a ratio ranging from 90:10 to 95:5.

[0214] Similarly, the above-mentioned first linear alkanediol:second alkanediol ratios or ratio ranges are also applicable to the mixture.

[0215] In yet another variant according to the second aspect of the invention, the mixture comprises as the first linear alkanediol a 2,3-alkanediol, such as 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol or 2,3-tridecanediol, and as the second linear alkanediol a corresponding 1,2-alkanediol , for example 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol in a ratio in the range of 50:50 to 99.9:0.1, preferably in a ratio in the range of 75:25 to 99:1, more preferably in a ratio in the range of 80:20 to 98:2, even more preferably in a ratio in the range of 90:10 to 95:5.

[0216] In a more advantageous variant according to the second aspect of the invention, a combination of a 1,2-alkanediol as the first linear alkanediol and a corresponding 2,3-alkanediol as the second linear alkanediol, e.g. 1,2-pentanediol and 2,3-pentanediol, or 1,2-hexanediol and 2,3-hexanediol, or 1,2-heptanediol and 2,3-heptanediol, or 1,2-octanediol and 2,3-octanediol, or 1,2-nonanediol and 2,3-nonanediol, or 1,2-decanediol and 2,2-decanediol, or 1,2-undecanediol and 2,3-undecanediol, or 1,2-dodecanediol and 2,3-dodecanediol, or 1,2-Tridecanediol and 2,3-Tridecanediol In the mixture comprising the first linear alkanediol and the second linear alkanediol, the first linear alkanediol and the second linear alkanediol are present in a ratio ranging from 50:50 to 99.9:0.1, preferably from 75:25 to 99:1, more preferably from 80:20 to 98:2, and even more preferably from 90:10 to 95:5.

[0217] Similarly, the above-mentioned first linear alkanediol:second alkanediol ratios or ratio ranges are also applicable to the mixture.

[0218] With these mixing ratios, the aforementioned mixtures exhibit improved solubility for lipophilic active substances in direct comparison with the corresponding individual substances, as will be explained and demonstrated in the experimental part.

[0219] In a more advantageous variant according to the second aspect of the invention, a mixture comprising a 2,3-alkanediol as the first linear alkanediol and the corresponding 1,2-alkanediol as the second linear alkanediol, e.g. 2,3-pentanediol and 1,2-pentanediol, or 2,3-hexanediol and 1,2-hexanediol, or 2,3-heptanediol and 1,2-heptanediol, or 2,3-octanediol and 1,2-octanediol, or 2,3-nonanediol and 1,2-nonanediol, or 2,3-decanediol and 1,2-decanediol, or 2,3-undecanediol and 1,2-undecanediol, or 2,3-dodecanediol and 1,2-dodecanediol, or 2,3-Tridecanediol and 1,2-Tridecanediol In the mixture comprising the first linear alkanediol and the second linear alkanediol, the first linear alkanediol and the second linear alkanediol are present in a ratio ranging from 50:50 to 99.9:0.1, preferably from 75:25 to 99:1, more preferably from 80:20 to 98:2, and even more preferably from 90:10 to 95:5.

[0220] Similarly, the above-mentioned first linear alkanediol:second alkanediol ratios or ratio ranges are also applicable to the mixture.

[0221] With these mixing ratios, the aforementioned mixtures exhibit improved solubility for lipophilic active substances in direct comparison with the corresponding individual substances, as will be explained and demonstrated in the experimental part.

[0222] Preferred variations according to the second aspect of the present invention include mixtures comprising 1,2-hexanediol as the first linear alkanediol and 2,3-octanediol as the second linear alkanediol, or mixtures comprising 1,2-octanediol as the first linear alkanediol and 2,3-hexanediol as the second linear alkanediol, or mixtures comprising 1,2-octanediol as the first linear alkanediol and 2,3-heptanediol as the second linear alkanediol, in any of ratios in the range of 50:50 to 99.9:0.1, preferably in the range of 75:25 to 99:1, more preferably in the range of 80:20 to 98:2, and even more preferably in the range of 90:10 to 95:5.

[0223] Similarly, the above first linear alkanediol:second alkanediol ratios or ratio ranges are also applicable to the mixture.

[0224] With these mixing ratios, the aforementioned mixtures exhibit improved solubility for lipophilic active substances in direct comparison with the corresponding individual substances, as will be explained and demonstrated in the experimental part.

[0225] In a further advantageous variant according to the second aspect of the invention, the mixture comprises a first linear alkanediol and a second linear alkanediol, for example 1,2-pentanediol and 2,3-hexanediol, or 1,2-pentanediol and 1,2-heptanediol, or 1,2-pentanediol and 2,3-heptanediol, or 1,2-pentanediol and 2,3-octanediol, or 1,2-pentanediol and 1,2-nonanediol, or 1,2-Pentanediol and 2,3-Nonanediol wherein the first linear alkanediol and the second linear alkanediol are present in a ratio ranging from 50:50 to 99.9:0.1, preferably from 75:25 to 99:1, more preferably from 80:20 to 98:2, and even more preferably from 90:10 to 95:5.

[0226] Similarly, the above-mentioned first linear alkanediol:second alkanediol ratios or ratio ranges are also applicable to the mixture.

[0227] With these mixing ratios, the aforementioned mixtures exhibit improved solubility for lipophilic active substances in direct comparison with the corresponding individual substances, as will be explained and demonstrated in the experimental part.

[0228] Particularly preferred variants according to the second aspect of the invention are mixtures comprising 1,2-heptanediol as the first linear alkanediol and 1,2-octanediol as the second linear alkanediol, or mixtures comprising 1,2-heptanediol as the first linear alkanediol and 2,3-octanediol as the second linear alkanediol, or mixtures comprising 1,2-heptanediol as the first linear alkanediol and 1,2-octanediol as the second linear alkanediol. Also encompassed are mixtures comprising nonanediol, or mixtures comprising 1,2-heptanediol as a first linear alkanediol and 2,3-nonanediol as a second linear alkanediol, wherein the first linear alkanediol and the second linear alkanediol are present in a ratio ranging from 50:50 to 99.9:0.1, preferably from 75:25 to 99:1, more preferably from 80:20 to 98:2, or even more preferably from 90:10 to 95:5.

[0229] Similarly, the above-mentioned first linear alkanediol:second alkanediol ratios or ratio ranges are also applicable to the mixture.

[0230] With these mixing ratios, the aforementioned mixtures exhibit improved solubility for lipophilic active substances in direct comparison with the corresponding individual substances, as will be explained and demonstrated in the experimental part.

[0231] Alkanediols can be obtained from petrochemical or other fossil fuel sources by known methods such as olefin bishydroxylation, hydrolysis from epoxides, or various chemical conversions, or from bio-derived feedstocks by fermentation, or by synthesis from bio-based natural and renewable feedstocks such as biomass by catalytic synthesis, as described in US 2019 / 0241491 A1 and US 2020 / 0189995 A1. The alkanediols used in the present invention include both petrochemical-derived and bio-based natural and renewable feedstock-derived alkanediols. Preferably, the alkanediol is from a bio-based source and is therefore a bioalkanediol.

[0232] The compound (b) of the cosmetic or pharmaceutical composition or home care product according to the first or second aspect of the present invention relates to a lipophilic active component used in many cosmetic compositions, in particular skin care, hair care or body care, or pharmaceutical compositions.

[0233] The term "lipophilic" or "lipophilicity" refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene. Such non-polar solvents are lipophilic themselves. Therefore, lipophilic substances tend to dissolve in other lipophilic substances, while hydrophilic substances tend to dissolve in water and other hydrophilic substances. Therefore, a "lipophilic" substance is defined by the present invention in that it is not soluble in water at RTP at a concentration higher than 0.01% by weight. The water solubility of a substance is the saturation mass concentration of the substance in water at ambient temperature.

[0234] The term "active component" in the context of the present invention means a component or substance that confers, functions or operates to provide one or more benefits through one or more modes of action, such as anti-inflammatory, anti-itch, anti-redness, anti-dandruff, anti-microbial, antiperspirant, deodorizing, hair growth enhancing, anti-blemish, anti-cellulite, anti-viral, antioxidant, anti-wrinkle, skin lightening, skin tanning, pain reducing, edema reducing, skin barrier strengthening, anti-fungal, anti-sagging and skin soothing properties.

[0235] The lipophilic active components according to the first and second aspects of the present invention have a log P of ≧0 to 25.00. O / W Preferably, the lipophilic active component has a log P calculated by EPISuite v4.40 (US Environmental Protection Agency, calculated by KOWWIN v1.68) of ≥ 0 to 20.00. O / W A log P value range, more preferably ≥ 0 to 16.00 O / W A log P value range, particularly preferably ≧0 to 5.00 O / W It has a range of values. O / W The higher the value, the less soluble the lipophilic active component is in aqueous systems such as aqueous, aqueous / alcoholic, or aqueous / glycolic solutions. More preferred is a log P of the lipophilic active component of ≧1.00 to ≦4.00. O / W It is a range of values.

[0236] In general, the log P value is a constant defined as follows: log P = log10 (partition coefficient). The partition coefficient, P = [organic] / [aqueous], where [] indicates the concentration of the solute in the organic and aqueous partition, in this case, 1-octane and water. A negative log P value indicates that the compound has a higher affinity for the aqueous phase (is more hydrophilic). When log P = 0, the compound partitions equally between the lipid and aqueous phases. A positive log P value indicates a higher concentration in the lipid phase (i.e., the compound is more lipophilic). A log P = 1 indicates a 10:1 organic:aqueous partition. Log P values ​​are important to many industries and research fields in determining chemical delivery methods. In the pharmaceutical / biotechnology industry, log P is used to understand the behavior of drug molecules in the body. Drug candidates are often screened according to log P, among other criteria, to help guide drug selection and analog optimization. This is because lipophilicity is a major determinant in a compound's absorption, biodistribution, penetration across biological membranes and barriers, metabolism, and excretion (ADME properties). O / W The value should preferably be ≧0, more preferably in the range of ≧0.50 to 16.00.

[0237] The lipophilic active component in the cosmetic or pharmaceutical composition or home care product according to the first or second aspect of the invention is either a lipophilic cosmetic active component or a lipophilic pharmaceutical active component.

[0238] The lipophilic active component in the cosmetic or pharmaceutical composition or home care product according to the invention is tocopherol (log P O / W :12.18), bisabolol (log P O / W : 5.63), ethylhexylglycerin (log P O / W :2.22), o-cymen-5-ol (log P O / W : 3.52), propanediol caprylate (log P O / W :2.84), glyceryl caprylate (log PO / W :1.71), retinol palmitate (log P O / W :15.51), retinol (log P O / W :7.62), farnesol (log P O / W :5.77), glyceryl laurate (log P O / W :3.67), polyglyceryl-2 caprylate (log P O / W :>1), hydroxyacetophenone (log P O / W :1.19), caffeine (log P O / W : 0.16), undecylenoylphenylanine (log P O / W :5.31), phenylethyl resorcinol (log P O / W :3.19), hydroxymethoxyphenyldecanone (log P O / W :4.62), Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3 (log P O / W :>1), palmitoyl tripeptide-1 (log P O / W :>1), palmitoyl tetrapeptide-7 (log P O / W :>1), palmitoyl pentapeptide-4 (log P O / W :>1), retinoic acid hydroxypinacolone (log P O / W :8.93), Isochrysis Galbana Extract, Sclareolide (log P O / W : 3.86), vanillyl butyl ether (log P O / W :2.59), hydroxyphenylpropamidobenzoic acid (log P O / W : 3.71), 4-t-butylcyclohexanol (log P O / W :3.42), ubiquinone-10 (log P O / W :23.40), climbazole (log P O / W :3.72), decylene glycol (log P O / W :2.66), and at least one lipophilic cosmetically active component selected from the group consisting of a mixture of two or more of the aforementioned lipophilic cosmetically active components. The lipophilic cosmetically active component has a log P in the range of ≧0 to 24.00.O / W It is characterized by its value.

[0239] The lipophilic active component in the cosmetic or pharmaceutical composition or home care product according to the invention is tocopherol (log P O / W :12.18), ethylhexylglycerin (log P O / W :2.22), o-cymen-5-ol (log P O / W : 3.52), propanediol caprylate (log P O / W :2.84), glyceryl caprylate (log P O / W :1.71), retinol palmitate (log P O / W :15.51), retinol (log P O / W :7.62), farnesol (log P O / W :5.77), glyceryl laurate (log P O / W :3.67), polyglyceryl-2 caprylate (log P O / W :>1), hydroxyacetophenone (log P O / W :1.19), caffeine (log P O / W : 0.16), undecylenoylphenylalanine (log P O / W :5.31), phenylethyl resorcinol (log P O / W :3.19), hydroxymethoxyphenyldecanone (log P O / W :4.62), Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3 (log P O / W :>1), palmitoyl tripeptide-1 (log P O / W :>1), palmitoyl tetrapeptide-7 (log P O / W :>1), palmitoyl pentapeptide-4 (log P O / W :>1), retinoic acid hydroxypinacolone (log P O / W :8.93), Isochrysis Galbana Extract, Sclareolide (log P O / W : 3.86), vanillyl butyl ether (log P O / W:2.59), hydroxyphenylpropamidobenzoic acid (log P O / W : 3.71), 4-t-butylcyclohexanol (log P O / W :3.42), ubiquinone-10 (log P O / W :23.40), climbazole (log P O / W :3.72), decylene glycol (log P O / W :2.66) and a mixture of two or more of the aforementioned lipophilic cosmetically active components. The lipophilic cosmetically active component has a log P in the range of ≧0 to 24.00. O / W It is characterized by its value.

[0240] In an alternative variant, the lipophilic active component of the cosmetic or pharmaceutical composition or home care product of the present invention is erythromycin (log P O / W :2.48), betamethasone (log P O / W :1.72), ibuprofen (log P O / W :3.79), ketoprofen (log P O / W :3.00), diclofenac (log P O / W :0.57), metronidazole (log P O / W :0.00), imiquimod (log P O / W :3.06), celecoxib (log P O / W :3.47), indomethacin (log P O / W :4.23), caffeine (log P O / W :0.16), minoxidil (log P O / W : 0.27), hydrocortisone (log P O / W :1.62), dimethindene (log P O / W : 4.98) and a mixture of two or more of the aforementioned lipophilic pharmaceutically active components. The pharmaceutically active component has a log P in the range of ≧0 to 4.50. O / W It is characterized by its value.

[0241] In a particularly preferred variant, the lipophilic pharmaceutically active component of the cosmetic or pharmaceutical composition according to the invention is selected from the group consisting of minoxidil, dimethindene, caffeine, hydrocortisone and mixtures of two or more of the aforementioned lipophilic pharmaceutically active components.

[0242] The aforementioned lipophilic active components can be used as the sole component or in combination with one or more further lipophilic active components described above.

[0243] In a preferred variant, component (b) is different from component (a) of the cosmetic or pharmaceutical composition or home care product according to the invention.

[0244] In a preferred and advantageous variant, the cosmetic or pharmaceutical composition or home care product according to the first or second aspect of the invention comprises one of the following combinations of components (a) and (b): 1,2-Pentanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 1,2-Hexanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 1,2-Heptanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 1,2-Octanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 1,2-Nonanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 1,2-Decanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 1,2-Undecanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 1,2-Dodecanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 1,2-Tridecanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 2,3-Hexanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 2,3-Hexanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 2,3-Heptanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 2,3-Octanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 2,3-Nonanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 2,3-Decanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 2,3-Undecanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 2,3-Dodecanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 2,3-Tridecanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 2,3-Heptanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or One or more of 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, or 1,2-tridecanediol with tocopherol, bisabolol, ethylhexylglycerin, o-cymen-5-ol, propanediol caprylate, glyceryl caprylate, retinol palmitate, retinol, farnesol, glyceryl laurate, polyglyceryl-2 caprylate, hydroxyacetophenone, caffeine, undecylenoyl phenylalanine, phenylethyl resorcinol, hydroxymethoxyphenyl decanone, Zingiber officinale 1,2-heptanediol in combination with one or more lipophilic active ingredients selected from the group consisting of Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana Extract, Sclareolide, Vanillyl Butyl Ether, Hydroxyphenylpropamidobenzoic Acid, 4-t-Butylcyclohexanol, Ubiquinone-10, and Climbazole; or One or more of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, or 2,3-tridecanediol with tocopherol, bisabolol, ethylhexylglycerin, o-cymen-5-ol, propanediol caprylate, glyceryl caprylate, retinol palmitate, retinol, farnesol, glyceryl laurate, polyglyceryl-2 caprylate, hydroxyacetophenone, caffeine, undecylenoyl phenylalanine, phenylethyl resorcinol, hydroxymethoxyphenyl decanone, Zingiber officinale 1,2-heptanediol in combination with one or more lipophilic active ingredients selected from the group consisting of Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana Extract, Sclareolide, Vanillyl Butyl Ether, Hydroxyphenylpropamidobenzoic Acid, 4-t-Butylcyclohexanol, Ubiquinone-10, and Climbazole; or 2,3-Pentanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Hexanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Octanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Nonanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Decanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Undecanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Dodecanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Tridecanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Octanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Hexanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Heptanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Hexanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 1,2-Heptanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Heptanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Octanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 1,2-Nonanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Nonanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 1,2-Octanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Octanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 1,2-Nonanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Nonanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10 and climbazole in combination with one or more lipophilic active ingredients.

[0245] A more preferred combination of components (a) and (b) in a cosmetic or pharmaceutical composition or home care product according to the first or second aspect of the present invention is: 1,2-Heptanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 2,3-Heptanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole; or 2,3-Heptanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or One or more of 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, or 1,2-tridecanediol with tocopherol, bisabolol, ethylhexylglycerin, o-cymen-5-ol, propanediol caprylate, glyceryl caprylate, retinol palmitate, retinol, farnesol, glyceryl laurate, polyglyceryl-2 caprylate, hydroxyacetophenone, caffeine, undecylenoyl phenylalanine, phenylethyl resorcinol, hydroxymethoxyphenyl decanone, Zingiber officinale 1,2-heptanediol in combination with one or more lipophilic active ingredients selected from the group consisting of Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana Extract, Sclareolide, Vanillyl Butyl Ether, Hydroxyphenylpropamidobenzoic Acid, 4-t-Butylcyclohexanol, Ubiquinone-10, and Climbazole; or One or more of 2,3-pentanediol, 2,3-hexanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, or 2,3-tridecanediol with tocopherol, bisabolol, ethylhexylglycerin, o-cymen-5-ol, propanediol caprylate, glyceryl caprylate, retinol palmitate, retinol, farnesol, glyceryl laurate, polyglyceryl-2 caprylate, hydroxyacetophenone, caffeine, undecylenoyl phenylalanine, phenylethyl resorcinol, hydroxymethoxyphenyl decanone, Zingiber officinale 1,2-heptanediol in combination with one or more lipophilic active ingredients selected from the group consisting of Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana Extract, Sclareolide, Vanillyl Butyl Ether, Hydroxyphenylpropamidobenzoic Acid, 4-t-Butylcyclohexanol, Ubiquinone-10, and Climbazole; or 2,3-Pentanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Hexanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Octanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Nonanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Decanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Undecanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Dodecanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, and climbazole in combination with one or more lipophilic active components, or 2,3-Tridecanediol, Tocopherol, Bisabolol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10 and climbazole in combination with one or more lipophilic active components.

[0246] Even more preferred is the combination of components (a) and (b) in a cosmetic or pharmaceutical composition or home care product according to the first aspect of the invention: 1,2-Heptanediol, Tocopherol, Ethylhexylglycerin, o-Cymen-5-ol, Propanediol Caprylate, Glyceryl Caprylate, Retinol Palmitate, Retinol, Farnesol, Glyceryl Laurate, Polyglyceryl-2 Caprylate, Hydroxyacetophenone, Caffeine, Undecylenoyl Phenylalanine, Phenylethyl Resorcinol, Hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, Myristoyl Nonapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Pentapeptide-4, Retinoic Acid Hydroxypinacolone, Isochrysis Galbana (Isochrysis) Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10 and climbazole.

[0247] In further particularly advantageous variants, the cosmetic or pharmaceutical composition or home care product according to the first or second aspect of the invention comprises one of the following combinations of components (a) and (b): 1,2-pentanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-hexanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-heptanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-octanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-nonanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-decanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-undecanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-dodecanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-tridecanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 2,3-pentanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 2,3-hexanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 2,3-heptanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 2,3-octanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 2,3-nonanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 2,3-decanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 2,3-undecanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 2,3-dodecanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 2,3-tridecanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-heptanediol in combination with 2,3-heptanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-heptanediol in combination with one or more of 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol and one or more lipophilic active components selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-heptanediol in combination with one or more of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol or 2,3-tridecanediol and one or more lipophilic active components selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-pentanediol in combination with 2,3-pentanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-hexanediol in combination with 2,3-hexanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-octanediol in combination with 2,3-octanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-nonanediol in combination with 2,3-nonanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-decanediol in combination with 2,3-decanediol and one or more lipophilic active components selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-undecanediol in combination with 2,3-undecanediol and one or more lipophilic active components selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-dodecanediol in combination with 2,3-dodecanediol and one or more lipophilic active components selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-tridecanediol in combination with 2,3-tridecanediol and one or more lipophilic active components selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-hexanediol in combination with 2,3-octanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-octanediol in combination with 2,3-hexanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-octanediol in combination with 2,3-heptanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-pentanediol in combination with 2,3-hexanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-pentanediol in combination with 1,2-heptanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-pentanediol in combination with 2,3-heptanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-pentanediol in combination with 2,3-octanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-pentanediol in combination with 1,2-nonanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-pentanediol in combination with 2,3-nonanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-heptanediol in combination with 1,2-octanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-heptanediol in combination with 2,3-octanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-heptanediol in combination with 1,2-nonanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone, or 1,2-heptanediol in combination with 2,3-nonanediol and one or more lipophilic active ingredients selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil and hydrocortisone.

[0248] In a highly preferred and advantageous variant, the cosmetic or pharmaceutical composition or home care product according to the first or second aspect of the invention comprises one of the following combinations of components (a) and (b): 1,2-pentanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-hexanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-heptanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-octanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-nonanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-decanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-undecanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-dodecanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-tridecanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 2,3-pentanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 2,3-hexanediol and one or more lipophilic active ingredients selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 2,3-heptanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 2,3-octanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 2,3-nonanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 2,3-decanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 2,3-undecanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 2,3-dodecanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 2,3-tridecanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-heptanediol in combination with 2,3-heptanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-heptanediol in combination with one or more of 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-heptanediol in combination with one or more of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol or 2,3-tridecanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-pentanediol in combination with 2,3-pentanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-hexanediol in combination with 2,3-hexanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-octanediol in combination with 2,3-octanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-nonanediol in combination with 2,3-nonanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-decanediol in combination with 2,3-decanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-undecanediol in combination with 2,3-undecanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-dodecanediol in combination with 2,3-dodecanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-tridecanediol in combination with 2,3-tridecanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-hexanediol in combination with 2,3-octanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-octanediol in combination with 2,3-hexanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-octanediol in combination with 2,3-heptanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-pentanediol in combination with 2,3-hexanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-pentanediol in combination with 1,2-heptanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-pentanediol in combination with 2,3-heptanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-pentanediol in combination with 2,3-octanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-pentanediol in combination with 1,2-nonanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-pentanediol in combination with 2,3-nonanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-heptanediol in combination with 1,2-octanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-heptanediol in combination with 2,3-octanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-heptanediol in combination with 1,2-nonanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone, or 1,2-heptanediol in combination with 2,3-nonanediol and one or more lipophilic active components selected from the group consisting of minoxidil, dimethindene, caffeine and hydrocortisone.

[0249] In the most preferred variants, the cosmetic or pharmaceutical composition or home care product according to the first or second aspect of the invention comprises one of the following combinations of components (a) and (b): 1,2-pentanediol and caffeine, or 1,2-hexanediol and caffeine, or 1,2-heptanediol and caffeine, or 1,2-octanediol and caffeine, or 1,2-nonanediol and caffeine, or 1,2-decanediol and caffeine, or 1,2-undecanediol and caffeine, or 1,2-dodecanediol and caffeine, or 1,2-tridecanediol and caffeine, or 2,3-pentanediol and caffeine, or 2,3-hexanediol and caffeine, or 2,3-heptanediol and caffeine, or 2,3-octanediol and caffeine, or 2,3-nonanediol and caffeine, or 2,3-decanediol and caffeine, or 2,3-undecanediol and caffeine, or 2,3-dodecanediol and caffeine, or 2,3-tridecanediol and caffeine, or 1,2-heptanediol in combination with 2,3-heptanediol and caffeine, or 1,2-heptanediol in combination with one or more of 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol or 1,2-tridecanediol and caffeine, or 1,2-heptanediol in combination with one or more of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol or 2,3-tridecanediol and caffeine, or 1,2-pentanediol in combination with 2,3-pentanediol and caffeine, or 1,2-hexanediol in combination with 2,3-hexanediol and caffeine, or 1,2-octanediol in combination with 2,3-octanediol and caffeine, or 1,2-nonanediol in combination with 2,3-nonanediol and caffeine, or 1,2-decanediol in combination with 2,3-decanediol and caffeine, or 1,2-undecanediol in combination with 2,3-undecanediol and caffeine, or 1,2-dodecanediol in combination with 2,3-dodecanediol and caffeine, or 1,2-tridecanediol in combination with 2,3-tridecanediol and caffeine, or 1,2-hexanediol in combination with 2,3-octanediol and caffeine, or 1,2-octanediol in combination with 2,3-hexanediol and caffeine, or 1,2-octanediol in combination with 2,3-heptanediol and caffeine, or 1,2-pentanediol in combination with 2,3-hexanediol and caffeine, or 1,2-pentanediol in combination with 1,2-heptanediol and caffeine, or 1,2-pentanediol in combination with 2,3-heptanediol and caffeine, or 1,2-pentanediol in combination with 2,3-octanediol and caffeine, or 1,2-pentanediol in combination with 1,2-nonanediol and caffeine, or 1,2-pentanediol in combination with 2,3-nonanediol and caffeine, or 1,2-heptanediol in combination with 1,2-octanediol and caffeine, or 1,2-heptanediol in combination with 2,3-octanediol and caffeine, or 1,2-heptanediol in combination with 1,2-nonanediol and caffeine, or 1,2-heptanediol in combination with 2,3-nonanediol.

[0250] Among the above combinations, the combination of 1,2-heptanediol or 2,3-alkanediol, particularly 2,3-heptanediol or 2,3-octanediol, or an alkanediol mixture containing 1,2-alkanediol and 2,3-alkanediol, provides excellent solubility properties, i.e., lipophilic active ingredients can be solubilized in ready-to-use compositions or formulations, particularly aqueous, aqueous / alcoholic, or aqueous / glycolic solutions or emulsions, without crystallizing or precipitating from the compositions or formulations. This effect is demonstrated by the following examples.

[0251] The particular combinations of components (a) and (b) defined above can be recombined with one or more further components as described below.

[0252] In order to further increase the solubility of lipophilic active substances, the cosmetic or pharmaceutical compositions or home care products defined herein are advantageously combined with at least one solubilizer and / or at least one hydrophilic solvent.

[0253] In the context of the present invention, a solubilizer is a substance that helps solubilize an ingredient (solute) in a medium in which it would otherwise be insoluble.This definition is clear and excludes cosolubility, i.e., the use of mixed solvents such as alcohol and water in clear fragrance products.It also excludes changes in solubility caused by pH adjustment, such as the dissolution of lauric acid in aqueous ammonium hydroxide solution.The solubilization process generally requires the solute to become part of the micelles formed by the solubilizer.

[0254] Preferred solubilizers that can be used in the cosmetic or pharmaceutical compositions or home care products according to the first and second aspects of the invention, but which are of course not limited to: PEG-40 hydrogenated castor oil, polysorbate-20, 60 and 80, PEG-8, PEG-7 glyceryl cocoate, decyl glucoside, ceteareth-20, cetearyl glucoside, PEG-60 hydrogenated castor oil, steareth-2, steareth-20, PPG-26-buteth-26, PPG-5-laureth-5, steareth-21, trideceth-9, PEG-32, glycereth-26, polyglyceryl-3 distearate, methyl gluceth -20, PEG-12 laurate, polyglyceryl-4 caprylate, oleth-20, oleth-2, polyglyceryl-4 caprate, PPG-1-PEG-9 lauryl glycol ether, polyglyceryl-2 caprate, isocedeth-20, PPG-13-decyltetradeceth-24, 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, or a mixture of two or more of the foregoing solubilizers.

[0255] In a more preferred variant, the cosmetic or pharmaceutical composition or home care product according to the invention comprises a combination with one or more solubilizers selected from the group consisting of PEG-40 hydrogenated castor oil, polysorbates 20, 60 and 80, PEG-8, PEG-7 glyceryl cocoate, decyl glucoside, ceteareth-20, cetearyl glucoside, PEG-60 hydrogenated castor oil, steareth-2, steareth-20, PPG-26-buteth-26, PPG-5-laureth-5, steareth-21, trideceth-9 and mixtures of two or more of the aforementioned solubilizers.

[0256] Preferred hydrophilic solvents that can be used in the cosmetic or pharmaceutical compositions or home care products according to the first and second aspects of the invention include, but are not limited to: glycerin, propylene glycol, butylene glycol, isopropyl alcohol, propanediol, dipropylene glycol, propylene carbonate, ethanol, hexylene glycol, glycerin carbonate, methylpropanediol, butylene carbonate, dimethyl isosorbide, or a mixture of two or more of the aforementioned hydrophilic solvents.

[0257] The solubiliser and / or hydrophilic solvent is different from component (a) of the cosmetic or pharmaceutical composition or home care product according to the first and second aspects of the invention.

[0258] The cosmetic or pharmaceutical, in particular dermatological, compositions or home care products defined herein are preferably based on a carrier comprising at least one oil phase, although preparations based solely on water or water / alcohol or water / glycol are equally possible or preferred.

[0259] The oil phase or oil component in the cosmetic or pharmaceutical composition or home care product according to the invention that may be suitable is, for example, a vegetable oil, a hydrocarbon, a fatty alcohol, a fatty acid ester, a liquid UV filter, or a mixture of two or more of the aforementioned liquid oil components.

[0260] The oil phase or oil component in the cosmetic or pharmaceutical composition or home care product according to the invention is preferably a vegetable oil, even more preferably a liquid vegetable oil. It may also advantageously be a mixture of two or more vegetable oil components, in particular a mixture of liquid vegetable oils.

[0261] Vegetable oils or plant oils are oils extracted from seeds or, less commonly, from other parts of fruits. Like animal fats, vegetable oils are mixtures of triglycerides. Soybean oil, rapeseed oil, and cocoa butter are examples of vegetable oils derived from seeds. Olive oil, palm oil, and rice bran oil are examples of oils derived from other parts of fruits. In common usage, vegetable oil or plant oil may refer only to vegetable fats that are liquid at room temperature or at skin temperature of 35-37°C. Vegetable oils are generally edible.

[0262] The term "vegetable oil" also includes unsaturated vegetable oils. Unsaturated or vegetable oils can be converted to higher melting point oils by partial or complete "hydrogenation." The hydrogenation process involves "sparging" the oil with hydrogen at high temperature and pressure in the presence of a catalyst, typically a powdered nickel compound. Each carbon-carbon double bond is chemically reduced to a single bond, with two hydrogen atoms forming single bonds with two carbon atoms. The removal of double bonds by adding hydrogen atoms is called saturation, and as the degree of saturation increases, the oil progresses toward a fully hydrogenated state. Oils may be hydrogenated to increase their resistance to rancidity (oxidation) or to change their physical properties. As the degree of saturation increases, the viscosity and melting point of the oil increase.

[0263] In a preferred variant, the vegetable oil is selected from the group consisting of Persea Gratissima (Avocado Oil), Abies Alba (European Fir) Seed Oil, Acacia Victoriae (Elegant Wattle) Seed Oil, Actinidia Chinensis (Kiwi) Seed Oil, Amaranthus Hypochondriacus (Amaranth) Seed Oil, Arachis Hypogaea (Peanut) Oil, Astrocaryum Murumuru (Astrocaryum Murumuru) Seed Oil, Astrocaryum Tucuma (Astrocaryum Tucuma) Seed Oil, Astrocaryum Vulgare (Astrocaryum Vulgare) Fruit Oil, Astrocaryum Vulgare Kernel Oil, Avena Sativa (Oat) Kernel Oil, Brassica Alba Seed Oil, Brassica Campestris (Rapeseed) Seed Oil, Butyrospermum Parkii (Shea) Butter, Butyrospermum Parkii (Shea) Oil, Calendula Officinalis (Calendula) Seed Oil, Calophyllum Inophyllum (Calliflower) Seed Oil, Calophyllum Tacamahaca (Calophyllum Takanahaca) Seed Oil, Camellia Oleifera (Camellia) Seed Oil, Camellia Reticulata (Camellia) Seed Oil, Camellia Sinensis (Tea Plant) Seed Oil, Cannabis Sativa (Cannabis Sativa) Seed / Stem Oil, Canola Oil, Carthamus Tinctorius (Safflower) Seed Oil, Chlorella Vulgaris (Chlorella) Oil, Citrullus Lanatus (Watermelon) Seed Oil, Citrus Aurantifolia (Lime) Seed Oil, Citrus Aurantium Dulcis (Orange) Seed Oil, Citrus Grandis (Grapefruit) Seed Oil, Cocos Nucifera (Palm) Oil, Cocos Nucifera (Palm) Seed Butter, Coffea Arabica (Coffee) Seed Oil, Chlorella Oil (Biotechnology), CorylusAmericana (Hazelnut) Seed Oil, Corylus Avellana (Hazelnut) Seed Oil, Cucumis Melo (Melon) Seed Oil, Cucumis Sativus (Cucumber) Seed Oil, Cucurbita Pepo (Pumpkin) Seed Oil, Elaeis Guineensis (Palm) Oil, Elaeis (Palm) Fruit Oil, Glycine Soja (Soybean) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Gossypium Hirsutum (Cotton) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil, Macadamia Integrifolia Seed Oil, Macadamia Ternifolia Seed Oil, Mangifera Indica (Mango) Seed Oil, Mangifera Indica (Mango) Seed Oil, Melissa Officinalis (Lemon Balm) Seed Oil, Microalgae Oil, Moringa Oleifera (Moringa) Seed Oil, Moringa Peregrina (Moringa Peregrina) Seed Oil, Oenothera Biennis (Evening Primrose) Oil, Olea Europaea (Olive) Fruit Oil, Orus Oil, Orbignya Oleifera (Orbignya Oleifera) Seed Oil, Orbignya Speciosa (Orbignya Speciosa) Kernel Oil, Oryza Sativa (Rice) Bran / Germ Oil, Oryza Sativa (Rice) Bran Oil, Oryza Sativa (Rice) Germ Oil, Oryza Sativa (Rice) Lipid, Oryza Sativa (Rice) Seed Oil, Papaver Somniferum (Poppy) Seed Oil, Passiflora Edulis (Passion Fruit) Seed Oil, Persea Gratissima (Avocado) Fat, Persea Gratissima (Avocado) Oil, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Prunus Armeniaca (Apricot) Kernel Oil, Prunus Persica (Peach) Kernel Oil, Punica Granatum (Pomegranate) Seed Oil, Pyrus Malus (Apple) Seed Oil, Ricinoleic / Caproic / Caprylic / Capric Triglyceride, Ricinus Communis (Castor) Seed Oil, Rosa Canina (Dog Rose) Fruit Oil, RosaMoschata (Rosa Moschata) Seed Oil, Rubus Idaeus (Raspberry) Seed Oil, Sesamum Indicum (Sesame) Seed Butter, Soybean Glycerides, Theobroma Cacao (Cocoa) Seed Butter, Theobroma Grandiflorum (Theobroma Grandiflorum) Seed Butter, Triticum Vulgare (Wheat) Bran Lipid, Triticum Vulgare (Wheat) Germ Oil, Vitis Vinifera (Grape) Seed Oil, Zea Mays (Corn) Germ Oil, and Zea Mays (Corn) Oil.

[0264] In a particularly preferred variant, the cosmetic or pharmaceutical composition or home care product according to the first or second aspect of the invention comprises, as an oil component, a vegetable oil selected from the group consisting of caprylic capric triglyceride, Helianthus Annuus (Sunflower) seed oil, Simmondsia Chinensis (Jojoba) seed oil, Olea Europaea (Olive) fruit oil, Argania spinosa kernel oil (Argan oil), Prunus Amygdalus Dulcis (Sweet Almond) oil, Persea Gratissima (Avocado oil), Butyrospermum Parkii (Shea) butter, Cocos Nucifera (Palm) oil, Theobroma Cacao (Cocoa) seed butter, and mixtures of two or more of the aforementioned vegetable oils. The vegetable oil can be used either as a single component or in a mixture with one or more further different vegetable oils as mentioned above.

[0265] Hydrocarbons (mineral oils) are organic compounds generally composed only of hydrogen and carbon. When defined by IUPAC nomenclature or organic chemistry, the classification of hydrocarbons is as follows: 1. Saturated hydrocarbons are the simplest of the hydrocarbon species. They consist of only single bonds and are saturated with hydrogen. The formula for acyclic saturated hydrocarbons (i.e., alkanes) is C n H 2n+2 The most common form of saturated hydrocarbon is C n H2n+2(1-r) where r is the number of rings. Those with exactly one ring are cycloalkanes. Saturated hydrocarbons are the main components of petroleum fuels and are found in either linear or branched species. 2. Unsaturated hydrocarbons have one or more double or triple bonds between carbon atoms. Those with double bonds are called alkenes. Those with one double bond have the formula C n H 2n (assuming an acyclic structure). Those containing a triple bond are called alkynes. Those with one triple bond have the formula C n H 2n-2 It has. 3. Aromatic hydrocarbons, also known as arenes, are hydrocarbons that contain at least one aromatic ring.

[0266] Hydrocarbons may be liquids (e.g., hexane and benzene), waxes, or low-melting solids (e.g., paraffin wax and naphthalene), among others. The term "aliphatic" refers to non-aromatic hydrocarbons. Saturated aliphatic hydrocarbons are sometimes referred to as "paraffins." Mineral oils and waxes are mixtures of saturated hydrocarbons, primarily consisting of linear, branched, and cyclic structures with carbon chain lengths greater than C14. Mineral oils and waxes are chemicals prepared from naturally occurring petroleum crude oil. They are primarily composed of mineral saturated hydrocarbons (MOSH) and mineral aromatic hydrocarbons (MOAH). Hydrocarbons have been used for decades in skin care and lip care cosmetics due to their excellent skin tolerance, high protection and cleansing performance, and a wide range of viscosity options. In contrast to vegetable oils, mineral oils are highly stable and less susceptible to oxidation or rancidity, making them non-allergenic.

[0267] In a preferred variant, the hydrocarbons as oil constituents of the cosmetic or pharmaceutical composition or home care product of the invention are undecane, tridecane, mineral oil, petrolatum, squalane, isohexadecane, C7-C8 isoparaffins, C8-C9 isoparaffins, C9-C11 isoparaffins, C9-C12 isoparaffins, C9-C13 isoparaffins, C9-C14 isoparaffins, C9-C16 isoparaffins, C10-C11 isoparaffins, C10-C The hydrocarbons are selected from the group consisting of C12 isoparaffins, C10-C13 isoparaffins, C11-C12 isoparaffins, C11-C13 isoparaffins, C11-C14 isoparaffins, C12-C14 isoparaffins, C12-C15 isoparaffins, C12-C20 isoparaffins, C13-C14 isoparaffins, C13-C16 isoparaffins, C14-C16 isoparaffins, C15-C19 isoparaffins and C18-C70 isoparaffins. The hydrocarbons can be used either as a single component or in a mixture with one or more further different hydrocarbons as mentioned above.

[0268] In a particularly preferred variant, the oil component of the cosmetic or pharmaceutical composition or home care product of the invention is a hydrocarbon selected from the group consisting of hydrocarbons, petrolatum, squalane, isohexadecane, C13-C14 isoparaffins, and mixtures of two or more of the aforementioned hydrocarbons.

[0269] Fatty alcohols (or long-chain alcohols) are generally high-molecular-weight, straight-chain primary alcohols derived from natural fats and oils, but can range from low-carbon (4-6) to high-carbon (22-26). The exact chain length varies depending on the source. Some commercially important fatty alcohols are lauryl, stearyl, and oleyl alcohol. They are colorless, oily liquids (if they have fewer carbon atoms) or waxy solids, although impure samples may appear yellow. Fatty alcohols typically have an even number of carbon atoms and a single alcohol group (-OH) attached to a terminal carbon. Some are unsaturated, and some are branched. Most natural fatty alcohols are found as waxes, which are esters containing fatty acids and fatty alcohols. The traditional source of fatty alcohols is primarily various vegetable oils, which remain a large source of supply. Alcohols are obtained from triglycerides (fatty acid triesters), which make up the majority of oils. The process involves transesterifying triglycerides to produce methyl esters, which are then hydrogenated to obtain the fatty alcohols. Fatty alcohols are also prepared from petrochemical sources. In the Ziegler process, ethylene is oligomerized using triethylaluminum, followed by air oxidation. Alternatively, ethylene can be oligomerized to give a mixture of alkenes, which are subjected to hydroformylation, a process that produces odd-numbered aldehydes, which are then hydrogenated. Fatty alcohols are primarily used in the production of detergents and surfactants. They are also components of cosmetic solvents. They are used in cosmetics as co-emulsifiers, emollients, and thickeners.

[0270] In a preferred variant, the fatty alcohol as oil component of the cosmetic or pharmaceutical composition or home care product of the invention is selected from the group consisting of phenylpropanol, dimethylphenylbutanol, hexyldecanol, octyldodecanol, octyldodecanol, tridecyl alcohol, isostearyl alcohol, phenylisohexanol, phenylpropanol, trimethylbenzenepropanol, isoamyl alcohol, isostearyl alcohol and isotridecyl alcohol. The fatty alcohol can be used either as a single component or in a mixture with one or more further different fatty alcohols mentioned above.

[0271] Fatty acid esters are a type of ester resulting from the combination of fatty acids and alcohols. When the alcohol component is glycerol, the resulting fatty acid esters may be monoglycerides, diglycerides, or triglycerides. Fatty acid esters have conditioning effects that soften the skin and provide a smooth feel. They are also added to cosmetics to dissolve highly polar active ingredients and UV absorbers. Esters of straight-chain fatty acids and lower alcohols are effective in dissolving slightly soluble oil components with a light touch during application. Isostearic acid and other liquid oils containing branched and unsaturated fatty acids are commonly used as emollients. Esters of higher fatty acids and higher alcohols with relatively high melting points are added to skin creams to adjust the application feel.

[0272] In a preferred variant, the fatty acid esters as oil components of the cosmetic or pharmaceutical composition or home care product of the invention are C12-C15 alkyl benzoates, caprylic / lauric / myristic / oleic triglycerides, caprylic / capric triglycerides, caprylic / capric / lauric triglycerides, caprylic / capric / linoleic triglycerides, caprylic / capric / myristic / stearic Acid Triglyceride, Caprylic / Capric / Palmitic / Stearic Triglyceride, Caprylic / Capric / Stearic Triglyceride, Caprylic / Capric / Succinic Triglyceride, Caprylyl Caprylate, Cetearyl Ethylhexanoate, Cetearyl Isononanoate, Cetearyl Nonanoate, Coco-Caprylate, Decyl Cocoate, Decyl Oleate, Dicaprylyl Carbonate, Diethyl Succinate, Diethylhexyl 2,6-Naphthalate, Diethylhexyl Carbonate, Dibutyl Adipate, Diisopropyl Adipate, Dipropylheptyl Carbonate, Ethyl Laurate, Ethylhexyl Isononanoate, Ethylhexyl Palmitate, Ethylhexyl Stearate, Glyceryl Caprylate Caprate, Glyceryl Caprylate, Glyceryl Laurate, Glyceryl Triacetylhydroxystearate, Glyceryl Triacetylricinoleate, Hexyl Laurate, Isoamyl Acetate, Isoamyl Cocoate, Isopropyl Palmitate, Isosorbide Dicaprylate, Isopropyl Myristate, Myristyl Myristate, Oleic / Linoleic Triglyceride, Oleic / Palmitic Triglyceride, Oleic / Palmitic The hydroxybenzoates are selected from the group consisting of oleic / lauric / myristic / linoleic triglyceride, caprylic / propanediol, ricinoleic / caproic / caprylic / capric triglyceride, oleostearin, oleyl erucate, palmitic / stearic triglyceride, dicaprylic / capric propanediol, propylheptyl caprylate, stearyl heptanoate / stearyl caprylate, triheptanoin, trihydroxystearin, triisononanoin, triisopalmitin, triisostearin, trilaurin, trilinolein, trilinolenin, trimyristin, triolein, tripalmitin, tripalmitolein, tripelargonin, triricinolein, and tristearin.

[0273] In certain preferred variants, the oil component of the cosmetic or pharmaceutical composition or home care product of the invention is selected from the group consisting of C12-C15 alkyl benzoate, caprylic / capric triglyceride, caprylyl caprylate, cetearyl ethylhexanoate, cetearyl isononanoate, cetearyl nonanoate, coco-caprylate, decyl cocoate, decyl oleate, dicaprylyl carbonate, diethylhexyl 2,6-naphthalate, dibutyl adipate, diisopropyl adipate, ethyl laurate, ethylhexyl isononanoate, ethylhexyl palmitate. The fatty acid esters are selected from the group consisting of ethylhexyl stearate, glyceryl caprylate, glyceryl laurate, hexyl laurate, isoamyl cocoate, isopropyl palmitate, isopropyl myristate, myristyl myristate, propanediol caprylate, oleyl erucate, palmitic / stearic triglyceride, propanediol dicaprylate caprate, trihydroxystearin, triisostearin, triisononanoin, tristearin, and mixtures of two or more of the aforementioned fatty acid esters. The fatty acid esters can be used either as a single component or in a mixture with one or more additional different fatty acid esters described above.

[0274] UV filters are compounds or mixtures of compounds that block or absorb ultraviolet (UV) radiation. Because excessive UV radiation can cause sunburn, photoaging, and skin cancer, skin care products such as sunscreens generally include classifications for the specific wavelengths they filter. UV classifications include UVA (320-400 nm), UVB (290-320 nm), and UVC (200-280 nm). UV-absorbing compounds are used not only in sunscreens but also in other personal care products such as lipstick, shampoo, hairspray, body wash, toilet soap, and insect repellent. Chemical filters protect against UV radiation by absorbing, reflecting, or scattering. Reflection and scattering are achieved by inorganic physical UV filters such as titanium dioxide (TiO2) and zinc oxide (ZnO). Absorption of UVB radiation is primarily achieved by organic UV filters, also known as chemical UV filters.

[0275] In a preferred variant, the liquid UV filter as oil component of the cosmetic or pharmaceutical composition or home care product according to the invention is selected from the group consisting of octocrylene, ethylhexyl salicylate, homosalate, ethylhexyl methoxycinnamate, isoamyl p-methoxycinnamate, camphor benzalkonium methosulfate, polyarylamidomethylbenzylidene camphor, isooctyl methoxycinnamate, ethylhexyl triazone, drometrizole trisiloxane, diethylhexyl butamido triazone, 3-benzylidene camphor, octyl salicylate, ethylhexyl dimethyl PABA, bisethylhexyloxyphenol methoxyphenyl triazine, polysilicone-15, diethylamino hydroxybenzoylhexyl benzoate, N,N,N-trimethyl-4-(2-hydroxybenzoyl) ... 2-Ethylhexyl Ester / Octocrylene, 2-Ethylhexyl-4-Methoxycinnamate / Octinoxate, Ethoxylated Ethyl-4-aminobenzoate, 2-Ethylhexyl Salicylate / Octisalate, 2-Ethylhexyl-4-(dimethylamino)benzoate / Padimate O (USAN:BAN), 2,2'-Methylene-bis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethyl-butyl)phenol) / Bisoctrizole, and Dimethicodiethyl Benzalmalonate. The UV filters can be used either as single components or in mixtures with one or more further different UV filters as mentioned above.

[0276] In certain preferred variants, the oil component of the cosmetic or pharmaceutical composition or home care product of the invention is selected from the group consisting of octocrylene, ethylhexyl salicylate, homosalate, ethylhexyl methoxycinnamate, isoamyl p-methoxycinnamate, N,N,N-trimethyl-4-(2-oxoborn-3-ylidenemethyl)anilinium methyl sulfate, benzoic acid-2-hydroxy-3,3,5-trimethylcyclohexyl ester / homosalate, 2-cyano-3,3-diphenylacrylic acid, 2-ethylhexyl ester / octocrylene, 2-ethylhexyl and liquid UV filters selected from the group consisting of 2,2'-methylene-bis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethyl-butyl)phenol) / bisoctrizole, dimethicone diethyl benzalmalonate, 2,2'-methyl-4-methoxycinnamate / octinoxate, ethoxylated ethyl-4-aminobenzoate, 2-ethylhexyl salicylate / octisalate, 2-ethylhexyl-4-(dimethylamino)benzoate / padimate O (USAN:BAN), 2,2'-methylene-bis(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethyl-butyl)phenol) / bisoctrizole, dimethicone diethyl benzalmalonate, and mixtures of two or more of the foregoing UV filters.

[0277] In addition to the oil phase or oil component defined above, the cosmetic or pharmaceutical composition or home care product according to the invention preferably comprises one or more further oils. Suitable oils forming a constituent of the O / W emulsion are, for example, Guerbet alcohols based on fatty alcohols having 6 to 18, preferably 8 to 10, carbon atoms, esters of linear C5 to C22 fatty acids with linear or branched C5 to C22 fatty alcohols, or esters of branched C1 to C13 carboxylic acids with linear or branched C6 to C22 fatty alcohols, such as myristyl myristate, myristyl palmitate, myristyl stearate, myristyl isostearate, myristyl oleate, myristyl behenate, myristyl erucate, cetyl myristate, cetyl palmitate, cetyl stearate, cetyl isostearate, cetyl oleate, cetyl behenate, cetyl erucate, stearyl myristate, stearyl palmitate, stearyl stearate, stearyl isostearate, Examples of suitable oleic acid esters include stearyl oleate, stearyl behenate, stearyl erucate, isostearyl myristate, isostearyl palmitate, isostearyl stearate, isostearyl isostearate, isostearyl oleate, isostearyl behenate, isostearyl oleate, oleyl myristate, oleyl palmitate, oleyl stearate, oleyl isostearate, oleyl oleate, oleyl behenate, oleyl erucate, behenyl myristate, behenyl palmitate, behenyl stearate, behenyl isostearate, behenyl oleate, behenyl behenate, behenyl erucate, erucyl myristate, erucyl palmitate, erucyl stearate, erucyl isostearate, erucyl oleate, erucyl behenate, and erucyl erucate.Also included are esters of linear C6 to C22 fatty acids with branched alcohols, in particular 2-ethylhexanol, esters of C18 to C38 alkylhydroxycarboxylic acids with linear or branched C6 to C22 fatty alcohols, in particular dioctyl malate, esters of linear and / or branched fatty acids with polyhydric alcohols (such as propylene glycol, dimerdiol or trimertriol) and / or Guerbet alcohols, triglycerides based on C6 to C10 fatty acids, liquid mono- / di- / triglyceride mixtures based on C6 to C18 fatty acids, C6 to C22 fatty alcohols and / or Guerbet alcohols. Esters of alcohols with aromatic carboxylic acids, in particular benzoic acid, esters of C2-C12 dicarboxylic acids with linear or branched alcohols having 1 to 22 carbon atoms or polyols having 2 to 10 carbon atoms and 2 to 6 hydroxyl groups, vegetable oils, branched primary alcohols, substituted cyclohexanes, linear and branched CC-C22 fatty alcohol carbonates based on fatty alcohols having 6 to 18, preferably 8 to 10, carbon atoms, such as, for example, dicaprylyl carbonate (Cetiol® CC), Guerbet carbonate, benzoic acid with linear and / or branched C6-C 22 Esters of alcohols (e.g., Finsolv® TN), linear or branched, symmetrical or asymmetrical dialkyl ethers having 6 to 22 carbon atoms per alkyl group, such as dicaprylyl ether (Cetiol® OE), ring-opening products of epoxidized fatty acid esters and polyols, silicone oils (cyclomethicone, silicone methicone grades, etc.) and / or aliphatic or naphthenic hydrocarbons, such as squalane, squalene or dialkylcyclohexanes.

[0278] In the context of the present invention, it is also possible, and in some cases advantageous, to combine a cosmetic or pharmaceutical, in particular a dermatological composition or a home care product according to the first or second aspect of the invention with other active substances, adjuvants or additives different from the lipophilic active component (b) of the cosmetic or pharmaceutical composition according to the invention.

[0279] Active agents and / or adjuvants and / or additives commonly used in cosmetic or pharmaceutical compositions or home care products differ from the lipophilic active component (b) and in some cases provide one or more benefits or act via more than one mode of action.

[0280] Thus, optionally, other conventional active substances, adjuvants or additives for cosmetic or pharmaceutical compositions or home care products, as further described below, can be added as component (c), i.e. to obtain a ready-to-use cosmetic or pharmaceutical composition or formulation or home care product.

[0281] The cosmetic or pharmaceutical compositions according to the invention may advantageously contain other cosmetic or pharmaceutical active agents and / or adjuvants and / or additives or auxiliaries as are customarily used in such compositions, such as abrasives, anti-acne agents, agents against skin ageing, anti-cellulitis agents, anti-dandruff agents, anti-inflammatory agents, antimicrobial agents, anti-irritation agents, irritation suppressants, antioxidants, astringents, deodorants, antiperspirants, preservatives, antistatic agents, binders, buffers, carrier substances, chelating agents, cell stimulants, cleansing agents, depilatories, as further described below. , surfactants, deodorants, antiperspirants, fabric softeners, emulsifiers, enzymes, enzyme inhibitors, essential oils, fibers, film formers, fixatives, foam formers, foam stabilizers, anti-foaming substances, foam promoters, gelling agents, gel-forming agents, hair care products, hair styling products, hair styling products, moisturizers, moisturizing substances, moisture-retaining substances, bleaching agents, strengthening agents, stain removers, optical brighteners, impregnating agents, stain resistant agents, dyes, friction reducers, lubricants, moisturizing creams, ointments, opacifying agents, plasticizers, coatings, polishing agents, preservatives, glossing agents, green and synthetic polymers, powders, proteins , re-oiling agents, abrasives, silicones, skin soothing agents, skin cleansing agents, skin care agents, skin healing agents, skin lightening agents, skin protectants, skin emollients, hair promoters, cooling agents, skin cooling agents, heat retaining agents, skin heat retaining agents, stabilizers, surfactants, UV absorbers, UV filters, primary sun protection factors, secondary sun protection factors, detergents, fabric conditioning agents, suspending agents, skin tanning agents, active agents that regulate skin or hair pigmentation, matrix metalloproteinase inhibitors, skin moisturizers, glycosaminoglycan stimulators, TRPV1 antagonists, desquamating agents, anti-cellulite or fat-enhancing agents, hair growth activators or inhibitors, thickeners, rheological additives, vitamins, oils, waxes, pearlescent waxes, fats, phospholipids, saturated fatty acids, mono- or polyunsaturated fatty acids, alpha-hydroxy acids, polyhydroxy fatty acids, liquefying agents, dyes, color protectants, pigments, rust inhibitors, fragrances or perfume oils, aromas, flavoring substances, odorous substances, polyols, electrolytes, organic solvents, etc., and mixtures of two or more of the foregoing substances may be combined.

[0282] Of the above-mentioned cosmetic or pharmaceutical active agents and / or adjuvants and / or additives or auxiliaries, agents against skin ageing, antimicrobial agents, antioxidants, chelating agents, emulsifiers, surfactants, preservatives, green and synthetic polymers, skin cooling agents, rheological additives, oils, fragrances or perfume oils and polyols are particularly preferred for the preparation of cosmetic and pharmaceutical compositions.

[0283] As dermatological conditions or diseases are often accompanied by dry skin, scratchy skin, skin lesions or inflammation, the cosmetic or pharmaceutical composition according to the invention advantageously contains an active compound such as, preferably, an anti-inflammatory, antibacterial or antifungal substance, a substance with redness-reducing or itching-reducing action, an analgesic substance, a moisturizer and / or cooling agent, an osmotic agent, a keratolytic substance, a nutritional substance, an anti-inflammatory, antibacterial or antifungal substance, a substance with redness-reducing or itching-reducing action, an analgesic substance, an antidandruff substance, or a solvent, fragrance, antioxidant, preservative, (metal) chelating agent, penetration enhancer, as further described below, or a mixture of two or more of the aforementioned agents.

[0284] Anti-aging active agents: The cosmetic or pharmaceutical compositions according to the invention preferably contain one or more anti-aging active agents. In the context of the present invention, anti-aging or bioactive agents are, for example, antioxidants, matrix metalloproteinase inhibitors (MMPIs), skin moisturizers, glycosaminoglycan stimulators, anti-inflammatory agents, TRPV1 antagonists and plant extracts.

[0285] Antioxidants: Preferred cosmetic or pharmaceutical compositions according to the present invention comprise one or more antioxidants. Suitable antioxidants include amino acids (preferably glycine, histidine, tyrosine, tryptophan) and derivatives thereof, imidazole (preferably urocanic acid) and derivatives thereof, peptides, preferably D,L-carnosine, D-carnosine, L-carnosine and derivatives thereof (preferably anserine), carnitine, creatine, matrikine peptides (preferably lysyl-threonyl-threonyl-lysyl-serine) and palmitoylated pentapeptides, carotenoids, carotenes (preferably alpha-carotene, beta-carotene, lycopene) and derivatives thereof, lipoic acid and derivatives thereof (preferably dihydrolipoic acid), aurothioglucose, propylthiouracil and other thiols (preferably thioredoxin, glutathione, cysteine, cystine, cystamine and glycosyl, N-acetyl, methyl, ethyl, propyl, amyl, butyl and lauryl, palmitoyl, oleyl, gamma-linoleyl, cholesteryl, glyceryl and its oligoglyceryl esters) and salts thereof, dilauryl thiodipropionate, thio Distearyl thiodipropionate, thiodipropionic acid and derivatives thereof (preferably esters, ethers, peptides, lipids, nucleotides, nucleosides and salts), as well as very small tolerable amounts (e.g., pmol to μmol / kg) of sulfoximine compounds (preferably buthionine sulfoximine, homocysteine ​​sulfoximine, buthionine sulfone, penta-, hexa-, heptathionine sulfoximine), and (metal) chelating agents (preferably alpha-hydroxy fatty acids, palmitic acid, phytic acid, lactate). Feline, alpha-hydroxy acids (preferably citric acid, lactic acid, malic acid), humic acid, bile acids, bile extract, tannins, bilirubin, biliverdin, EDTA, EGTA and derivatives thereof, unsaturated fatty acids and derivatives thereof (preferably gamma-linolenic acid, linoleic acid, oleic acid), folic acid and derivatives thereof, ubiquinone and derivatives thereof, ubiquinol and derivatives thereof, vitamin C and derivatives (preferably ascorbyl palmitate, magnesium ascorbyl phosphate, ascorbyl acetate, ascorbyl glucoside),Tocopherols and derivatives (preferably vitamin E acetate), vitamin A and derivatives (vitamin A palmitate), and coniferyl benzoate of benzoic acid resin, rutinic acid and derivatives, flavonoids and their glycosylated precursors, in particular quercetin and its derivatives, preferably alpha-glucosylrutin, rosmarinic acid, carnosol, carnosolic acid, resveratrol, caffeic acid and derivatives, sinapic acid and derivatives, ferulic acid and derivatives, curcuminoids, chlorogenic acid and derivatives, retinoids, preferably retinol palmitate, retinol or tretinoin, ursolic acid, levulinic acid, butylhydroxytoluene, butylhydroxyanisole, nordihydroguaiac acid, nordihydroguaiaretic acid, trihydroxybutyric acid, ... These include tyrophenone, uric acid and its derivatives, mannose and its derivatives, zinc and its derivatives (preferably ZnO, ZnSO), selenium and its derivatives (preferably selenomethionine), superoxide dismutase, stilbene and its derivatives (preferably stilbene oxide, trans-stilbene oxide), as well as derivatives of these listed active ingredients (salts, esters, ethers, sugars, nucleotides, nucleosides, peptides and lipids) that are suitable according to the invention, or plant extracts or fractions with antioxidant action, preferably green tea, rooibos, honeybush, grape, rosemary, sage, melissa, thyme, lavender, olive, oat, cocoa, ginkgo, ginseng, licorice, honeysuckle, sophora, pueraria, pine, citrus fruits, Phyllanthus emblica or St. John's wort, grape seed, wheat germ, Phyllanthus emblica, coenzymes, preferably coenzyme Q10, plastoquinone and menaquinone. Preferred antioxidants are selected from the group consisting of vitamin A and derivatives, vitamin C and derivatives, tocopherol and derivatives, preferably tocopheryl acetate and ubiquinone. When vitamin E and / or its derivatives are used as antioxidants, it is advantageous to select their concentration from the range of about 0.001 to about 10% by weight based on the total weight of the composition. Vitamin A or vitamin A derivatives,Alternatively, when carotene or a derivative thereof is used as an antioxidant, the concentration thereof is advantageously selected from the range of about 0.001 to about 10% by weight based on the total weight of the composition.

[0286] Matrix-metalloproteinase inhibitors (MMPI): A preferred cosmetic or pharmaceutical composition according to the invention comprises ursolic acid, retinol palmitate, propyl gallate, precocene, 6-hydroxy-7-methoxy-2,2-dimethyl-1(2H)-benzopyran, 3,4-dihydro-6-hydroxy-7-methoxy-2,2-dimethyl-1(2H)-benzopyran, benzamidine hydrochloride, the cysteine ​​proteinase inhibitor N-ethylmalemide, and the serine protease inhibitor epsilon-amino-n-caproic acid; phenylmethylsulfonylfluoride, colhibin (Pentapharm, INCI: Hydrolyzed Rice Protein), oenotherol (Soliance, INCI: Propylene Glycol, Aqua, Oenothera biennis root extract (e.g., ellagic acid and ellagitannins from pomegranate), phosphoramidon hinokitiol, EDTA, galardin, EquiStat (Collaborative Group, Apple fruit extract, Soybean seed extract, Ursolic acid, Soy isoflavones and Soy protein), Sage extract, MDI (Atrium, INCI: glycosaminoglycans), Fermiskin (Silab / Mawi, INCI: water and Lentinus edodes extract), actimp 1.9.The active ingredients include one or more matrix metalloproteinase inhibitors selected from the group consisting of: 3 (Expanscience / Rahn, INCI: Hydrolyzed Lupin Proteins), Lipobersoyaglycone (Mibelle, INCI: Alcohol, Polysorbate 80, Lecithin, and Soy Isoflavones), extracts from green and black tea, and further plant extracts, proteins or glycoproteins from soybeans, hydrolyzed proteins from rice, pea, or lupin, plant extracts that inhibit MMPs, preferably extracts from Shiitake mushrooms, extracts from leaves of the Rosaceae family, subfamily Rosoideae, and most particularly extracts of blackberry leaves, such as SymMatrix (Symrise, INCI: Maltodextrin, Rubus Fruticosus (Blackberry) Leaf Extract), particularly those that inhibit matrix metalloproteinases that enzymatically cleave collagen. Preferred active agents are selected from the group consisting of retinol palmitate, ursolic acid, extracts from leaves of the Rosaceae family, subfamily Rosaceae, genistein, and daidzein.

[0287] Skin moisturizers: Preferred cosmetic or pharmaceutical compositions according to the present invention comprise one or more skin moisturizers. Preferred skin moisturizers are alkanediols or alkanetriols containing 3 to 12 carbon atoms, preferably C3-C6 10 -Alkanediols and C3-C 10 More preferably, the skin moisturizer is selected from the group consisting of glycerol, 1,2-propylene glycol, 1,2-butylene glycol, 1,3-butylene glycol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, and 1,2-decanediol.

[0288] Glycosaminoglycan stimulators: Preferred cosmetic or pharmaceutical compositions according to the invention contain one or more substances stimulating the synthesis of glycosaminoglycans selected from the group consisting of hyaluronic acid and derivatives or salts, Subliskin (Sederma, INCI: Sinorhizobium Meliloti Ferment Filtrate, Cetyl Hydroxyethylcellulose, Lecithin), Hyalufix (BASF, INCI: Water, Butylene Glycol, Alpinia Galanga Leaf Extract, Xanthan Gum, Caprylic / Capric Triglyceride), Stimulhyal (Soliance, INCI: Calcium Ketogluconate), Syn-Glycan (DSM, INCI: Tetradecylaminobutyroylvalylaminobutyric Urea Trifluoroacetate, Glycerin, Magnesium Chloride), Kalpariane (Biotech Marine), DC Upregulex (Distinctive Cosmetic Ingredients (INCI: Water, Butylene Glycol, Phospholipids, Hydrolyzed Sericin), Glucosamine, N-acetylglucosamine, Retinoids, preferably Retinol and Vitamin A, Arctium lappa Fruit Extract, Eriobotrya japonica Extract, Genkwanin, N-Methyl-L-Serine, (-)-alpha-bisabolol or synthetic alpha-bisabolol such as Dragosantol and Dragosantol 100 from Symrise, Oat Glucan, Echinacea purpurea Extract and Soy Protein Hydrolysate. Preferred active agents are selected from the group consisting of hyaluronic acid and derivatives or salts, retinol and derivatives, (-)-alpha-bisabolol or synthetic alpha-bisabolol, such as Dragosantol and Dragosantol 100 from Symrise, oat glucan, Echinacea purpurea (Echinacea purpurea) extract, Sinorhizobium Meliloti (Alfalfa) ferment broth, calcium ketogluconate, Alpinia galanga (Panthera alba) leaf extract, and tetradecylaminobutyroylvalylaminobutyric acid urea trifluoroacetate.

[0289] TRPV1 Antagonists: Preferred cosmetic or pharmaceutical compositions according to the present invention comprise one or more TRPV1 antagonists. Suitable compounds that reduce the hypersensitivity of skin nerves by acting as TRPV1 antagonists include, for example, trans-4-tert-butylcyclohexanol, or indirect modulators of TRPV1 by activating the μ receptor, such as acetyl tetrapeptide-15, are preferred.

[0290] Plant extracts: Preferred cosmetic or pharmaceutical compositions according to the present invention comprise one or more plant extracts. Plant extracts, special highly active plant extract fractions, and even highly purified active substances isolated from plant extracts can be used in cosmetic or pharmaceutical compositions according to the present invention. Extracts, fractions, and active substances from chamomile, aloe vera, Commiphora, Rubia, willow, willowherb, ginger, marigold, arnica, Glycyrrhiza, Echinacea, and Rubus are particularly preferred, as well as pure substances such as bisabolol, apigenin, apigenin-7-glucoside, gingerols such as [6]-gingerol, paradols such as [6]-paradol, boswellic acid, plant sterols, glycyrrhizin, glabridin, or licochalcone A.

[0291] Anti-inflammatory agents: The cosmetic or pharmaceutical compositions according to the invention preferably also contain anti-inflammatory and / or redness and / or itching relieving ingredients, in particular steroid substances of the corticosteroid type selected from the group consisting of hydrocortisone, dexamethasone, dexamethasone phosphate, methylprednisolone or cortisone are advantageously used as anti-inflammatory active ingredients or active ingredients that relieve redness and itching, the list of which can be expanded by adding other steroidal anti-inflammatory agents. Non-steroidal anti-inflammatory agents can also be used. More particularly: (i) steroidal anti-inflammatory substances of the corticosteroid type, in particular hydrocortisone, hydrocortisone derivatives such as hydrocortisone 17-butyrate, dexamethasone, dexamethasone phosphate, methylprednisolone or cortisone; (ii) nonsteroidal anti-inflammatory substances, in particular oxicams such as piroxicam or tenoxicam, salicylates such as aspirin, disalcid, solprin or fendosal, acetic acid derivatives such as diclofenac, fenclofenac, indomethacin, sulindac, tolmetin or clindanac, fenamic acids such as mefenam, meclofenam, flufenam or niflumic acid, propionic acid derivatives such as ibuprofen, naproxen or benoxaprofen, pyrazoles such as phenylbutazone, oxyphenylbutazone, febrazone or azapropazone, (iii) natural or naturally occurring anti-inflammatory substances or substances that reduce redness and / or itching, in particular extracts or fractions from chamomile, aloe vera, Commiphora, Rubia, willow, willow herb, oat, calendula, arnica, St. John's wort, honeysuckle, rosemary, Passiflora incarnata, witch hazel, ginger or echinacea, or single active compounds thereof; (iv) histamine receptor antagonists, serine protease inhibitors (e.g., soybean extracts), TRPV1 antagonists (e.g., 4-t-butylcyclohexanol), NK1 antagonists (e.g., aprepitant, hydroxyphenylpropamidobenzoic acid), cannabinoid receptor agonists (e.g., palmitoylethanolamine), and TRPV3 antagonists.

[0292] Examples that may be mentioned here are oxicams such as piroxicam or tenoxicam, salicylates such as aspirin, disalcid, solprin or fendosal, acetic acid derivatives such as diclofenac, fenclofenac, indomethacin, sulindac, tolmetin or clindanac, fenamic acids such as mefenamic acid, meclofenamic acid, flufenamic acid or niflumic acid, propionic acid derivatives such as ibuprofen, naproxen, benoxaprofen, or pyrazoles such as phenylbutazone, oxyphenylbutazone, febrazone or azapropazone. Anthranilic acid derivatives are preferred antipruritic ingredients in the compositions according to the invention.

[0293] Also useful are mixtures of natural or naturally occurring anti-inflammatory substances or mixtures of substances that reduce redness and / or itching, in particular extracts or fractions of chamomile, aloe vera, Commiphora species, Rubia species, willow, willow herb, oat, calendula, arnica, St. John's wort, honeysuckle, rosemary, Passiflora incarnata (passionflower), witch hazel, ginger or echinacea, preferably extracts or fractions of chamomile, aloe vera, oat, calendula, arnica, honeysuckle, rosemary, witch hazel, ginger or echinacea, and / or pure substances, preferably alpha-bisabolol, apigenin, apigenin-7-glucoside, gingerol, shogaol, gingerdiol, dehydrogingerdione, paradol, natural or naturally occurring avena avenanthramides, preferably tranilast, avenanthramide A, avenanthramide B, avenanthramide C, non-naturally occurring or non-naturally occurring avenanthramides, preferably dihydroavenanthramide D, dihydroavenanthramide E, avenanthramide D, avenanthramide E, avenanthramide F, boswellic acid, plant sterols, glycyrrhizin, glabridin and licochalcone A, preferably alpha-bisabolol, natural avenanthramides, non-natural avenanthramides, preferably dihydroavenanthramide D (WO 2004 047833A1), boswellic acid, plant sterols, glycyrrhizin and licochalcone A, and / or allantoin, panthenol, lanolin, (pseudo)ceramides [preferably ceramide 2, hydroxypropyl bispalmitamide MEA, cetyloxypropyl glyceryl methoxypropyl myristamide, N-(1-hexadecanoyl)-4-hydroxy-L-proline (1-hexadecyl) ester, hydroxyethyl palmityloxyhydroxypropyl palmitamide], glycosphingolipids, plant sterols, chitosan, mannose, lactose and β-glucans, in particular 1,3->1,4-β-glucan from oat.

[0294] When used in the context of the present invention, bisabolol may be of natural or synthetic origin, preferably "alpha-bisabolol." Preferably, the bisabolol used is synthetically prepared or natural (-)-alpha-bisabolol and / or synthetic mixed isomer alpha-bisabolol. When natural (-)-alpha-bisabolol is used, it can also be used as a component of essential oils or plant extracts or fractions thereof, for example, as a component (fraction) of oils or extracts of chamomile or Vanillosmopsis (particularly Vanillosmopsis erythropappa or Vanillosmopsis arborea). Synthetic alpha-bisabolol is available, for example, from Symrise under the name "Dragosantol."

[0295] When ginger extract is used in the context of the present invention, preferably an extract of fresh or dried ginger root is used, prepared by extraction with methanol, ethanol, isopropanol, acetone, ethyl acetate, carbon dioxide (CO2), hexane, methylene chloride, chloroform or other solvents or solvent mixtures of comparable polarity. The extract is characterized by the presence of active skin irritation-reducing amounts of components such as gingerols, shogaols, gingerdiols, dehydrogingerdione and / or paradols.

[0296] Physiological cooling agents: The cosmetic or pharmaceutical compositions according to the invention can be particularly advantageously combined with one or more physiological cooling agents. The use of cooling agents can alleviate itching. Preferred individual cooling agents for use within the framework of the present invention are listed below. Those skilled in the art can add many other cooling agents to this list. The listed cooling agents can also be used in combination with one another, which are preferably selected here from the following list: menthol and menthol derivatives (e.g. L-menthol, D-menthol, racemic menthol, isomenthol, neoisomenthol, neomenthol), menthyl ethers (e.g. (l-menthoxy)-1,2-propanediol, (l-menthoxy)-2-methyl-1,2-propanediol, l-menthyl-methyl ether), menthone glyceryl acetal, menthone glyceryl ketal or a mixture of both, menthyl esters (e.g. menthyl formiate, menthyl acetate, menthyl isobutyrate, menthyl hydroxyisobutyrat, methyl lactate, methyl methyl ether ... Menthyl, L-menthyl-L-lactate, L-menthyl-D-lactate, menthyl-(2-methoxy)acetate, menthyl-(2-methoxyethoxy)acetate, menthyl pyroglutamate), menthyl carbonates (e.g., menthyl propylene glycol carbonate, menthyl ethylene glycol carbonate, menthyl glycerol carbonate or mixtures thereof), half esters of menthol with dicarboxylic acids or derivatives thereof (e.g., monomenthyl succinate, monomenthyl glutarate, monomenthyl malonate, O-menthyl succinic acid ester-N,N-(dimethyl)amide, O-menthyl succinic acid ester amide), menthanecarboxylic acid amides (in this case, preferably menthanecarboxylic acid-N-ethylamide [WS3] or N-methyl-N ... α-(menthanecarbonyl)glycine ethyl ester [WS5], menthanecarboxylic acid-N-(4-cyanophenyl)amide or menthanecarboxylic acid-N-(4-cyanomethylphenyl)amide, menthanecarboxylic acid-N-(alkoxyalkyl)amide, menthone and menthone derivatives (e.g., L-menthone glycerol ketal), 2,3-dimethyl-2-(2-propyl)-butyric acid derivatives (e.g., 2,3-dimethyl-2-(2-propyl)-butyric acid-N-methylamide [WS23]), isopulegol or its esters (l(-)-isopulegol, l(-)-isopulegol acetate), menthane derivatives (e.g., p-menthane-3,8-diol), cubebol or synthetic or synthetic compounds containing cubebol or natural mixtures, pyrrolidone derivatives of cycloalkyldione derivatives (e.g. 3-methyl-2(1-pyrrolidinyl)-2-cyclopenten-1-one) or tetrahydropyrimidin-2-ones (e.g. icilin or related compounds described in WO 2004 / 026840), further carboxamides (e.g. N-(2-(pyridin-2-yl)ethyl)-3-p-menthanecarboxamide or related compounds), (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(1-isopropyl)cyclohexane-carboxamide [WS12], oxamate and [(1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl]2-(ethylamino)-2-oxo-acetate (X Cool). Preferred cooling agents due to their particular synergistic effects are l-menthol, d-menthol, racemic menthol, menthone glycerol acetal (trade name: Frescolat® MGA), menthyl lactate (preferably l-menthyl lactate, especially l-menthyl l-lactate (trade name: Frescolat® ML)), substituted menthyl-3-carboxamides (such as menthyl-3-carboxylic acid N-ethylamide), 2-isopropyl-N-2,3-trimethylbutanamide, substituted cyclohexanecarboxamides, 3-menthoxypropane-1,2-diol, 2-hydroxyethyl menthyl carbonate, 2-hydroxypropyl menthyl carbonate, and isopulegol.Particularly preferred cooling agents are l-menthol, racemic menthol, menthone glycerol acetal (trade name: Frescolat® MGA), menthyl lactate (preferably l-menthyl lactate, in particular l-menthyl l-lactate (trade name: Frescolat® ML)), 3-menthoxypropane-1,2-diol, 2-hydroxyethyl menthyl carbonate and 2-hydroxypropyl menthyl carbonate. Very particularly preferred cooling agents are l-menthol, menthone glycerol acetal (trade name: Frescolat® MGA) and menthyl lactate (preferably l-menthyl lactate, in particular l-menthyl l-lactate (trade name: Frescolat® ML)).

[0297] Moisturizing and / or hydrating substances: Itching is particularly severe when the skin is dry. The use of moisturizing and / or hydrating substances can significantly reduce itching. Thus, the cosmetic or pharmaceutical composition according to the invention may advantageously also contain one or more of the following moisturizing and / or hydrating substances: sodium lactate, urea, urea derivatives, alcohols, diols such as glycerol, propylene glycol, hexylene glycol, collagen, elastin or hyaluronic acid, diacyladipates, petrolatum, urocanic acid, lecithin, panthenol, phytantriol, lycopene, (pseudo)ceramides, glycosphingolipids, cholesterol, phytosterols, chitosan, chondroitin sulfate, lanolin, lanolin esters, amino acids, alpha-hydroxy acids (such as citric acid, lactic acid, malic acid) and derivatives thereof, mono-, di- and oligosaccharides such as glucose, galactose, fructose, mannose, fructose, lactose, polysaccharides, for example R-glucans, in particular 1,3-1,4-β-glucan from oat, alpha-hydroxy fatty acids, triterpene acids such as betulinic acid or ursolic acid and algae extracts.

[0298] Analgesic substances: The cosmetic or pharmaceutical compositions according to the invention may also advantageously contain one or more analgesic substances, and any analgesic substance suitable or customary in cosmetic or pharmaceutical applications can be used, such as alpha-bisabolol, azulene, guaiazulene, 18-beta-glycyrrhetinic acid, allantoin, aloe vera juice or gel, Hamamelis virginiana (witch hazel), Echinacea, Centella asiatica, chamomile, Arnica monatana, Glycyrrhiza, algae, seaweed and Calendula officinalis (calendula), as well as vegetable oils such as sweet almond oil, baobab oil, olive oil, and panthenol, laureth-9, trideceth-9 and 4-t-butylcyclohexanol.

[0299] Antibacterial or antifungal active substances: Antibacterial or antifungal active substances can also be used particularly advantageously in the cosmetic or pharmaceutical compositions according to the invention, where any antibacterial or antifungal active substance suitable or customary for cosmetic or pharmaceutical, especially dermatological, applications can be used. In addition to the large group of conventional antibiotics, other products that are advantageous here include those relevant to cosmetics, such as, inter alia, triclosan, climbazole, octoxyglycerin, Octirox® (1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone 2-aminoethanol salt), chitosan, farnesol, glycerol monolaurate or combinations of said substances, which are used, inter alia, against body odor, foot odor or dandruff.

[0300] Antimicrobial agents: The cosmetic or pharmaceutical compositions according to the invention preferably contain one or more antimicrobial agents. Suitable antimicrobial agents are in principle all substances that are effective against gram-positive bacteria, such as 4-hydroxybenzoic acid and its salts and esters, N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea, 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), 4-chloro-3,5-dimethyl-phenol, 2,2'-methylenebis(6-bromo-4-chlorophenol), 3-methyl-4-(1-methylethyl)phenol, 2-benzyl-4-chloro-phenol, 3-(4-chlorophenoxy)-1,2- propanediol, 3-iodo-2-propynyl butylcarbamate, chlorhexidine, 3,4,4'-trichlorocarbanilide (TTC), antibacterial fragrance, thymol, thyme oil, eugenol, clove oil, menthol, mint oil, farnesol, phenoxyethanol, glycerol monocaprate, glycerol monocaprylate, glycerol monolaurate (GML), diglycerol monocaprate (DMC), salicylic acid N-alkylamides such as n-octyl salicylamide or n-decyl salicylamide.

[0301] Desquamating agents: The cosmetic or pharmaceutical composition according to the invention preferably contains one or more desquamating agents. The expression "desquamating agent" is understood to mean any compound capable of: - direct desquamating action by promoting exfoliation, for example beta-hydroxy acids, in particular salicylic acid and its derivatives (including 5-n-octanoylsalicylic acid), alpha-hydroxy acids, such as glycolic acid, citric acid, lactic acid, tartaric acid, malic acid or mandelic acid, urea, gentisic acid, oligofucose, cinnamic acid, Sophora japonica (Japanese pagoda) extract, resveratrol and some derivatives of jasmonic acid, - or action on enzymes involved in desquamation or degradation of corneodesmosomes, glycosidases, stratum corneum chymotryptic enzyme (SCCE) or other proteases (trypsin, chymotrypsin-like). Mention may also be made of agents that chelate inorganic salts: EDTA, N-acyl-N,N',N'-ethylenediaminetriacetic acid, aminosulfone compounds, in particular (N-2-hydroxyethylpiperazine-N-2-ethane)sulfonic acid (HEPES), derivatives of 2-oxothiazolidine-4-carboxylic acid (procysteine), derivatives of alpha-amino acids of the glycine type (such as sodium methylglycine diacetate, as described in EP-0 852 949 and sold by BASF under the trade name TRILON M), honey, sugar derivatives such as O-octanoyl-6-D-maltose and N-acetylglucosamine, chestnut extract, for example sold under the name Recoverine® by the company SILAB, prickly pear extract, for example sold under the name Exfolactive® by the company SILAB, or Phytosphingosine, sold by the company Degussa. SLC® (phytosphingosine grafted with salicylic acid).

[0302] Desquamating agents suitable for the present invention may in particular be selected from the group comprising sulfonic acids, calcium chelating agents, α-hydroxy acids such as glycolic acid, citric acid, lactic acid, tartaric acid, malic acid or mandelic acid, ascorbic acid and its derivatives such as ascorbyl glucoside and magnesium ascorbyl phosphate, nicotinamide, urea, (N-2-hydroxyethylpiperidine-N-2-ethane)sulfonic acid (HEPES), β-hydroxy acids such as salicylic acid and its derivatives, retinoids such as retinol and its esters, retinal, retinoic acid and its derivatives, chestnut or prickly pear extract, in particular commercially available from the company SILAB, reducing compounds such as cysteine ​​or cysteine ​​precursors.

[0303] Desquamating agents that can be used are also nicotinic acid and its esters, nicotinamide, also called vitamin B3 or vitamin PP, and ascorbic acid and its precursors.

[0304] Anti-dandruff substances: Furthermore, the cosmetic or pharmaceutical compositions according to the invention can also be used advantageously in combination with one or more anti-dandruff substances including triclosan, climbazole, octoxyglycerin, Octirox® (1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone 2-aminoethanol salt), chitosan, farnesol, glycerol monolaurate, propanedione monocaprylate or combinations of said substances, which are used especially against dandruff.

[0305] Further suitable antidandruff agents are piroctone olamine (1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-(1H)-pyridinone monoethanolamine salt), Baypival® (climbazole), Ketoconazol® (4-acetyl-1-{4-[2-(2,4-dichlorophenyl)r-2-(1H-imidazol-1-ylmethyl)-1,3-dioxiran-c-4-ylmethoxyphenyl}-piperazine, ketoconazole, Elbio The active ingredients are: ethanol, selenium disulfide, colloidal sulfur, sulfur polyethylene glycol sorbitan monooleate, sulfur ricinol polyethoxylate, sulfur tar distillate, salicylic acid (or in combination with hexachlorophene), undecylenic acid, monoethanolamide sulfosuccinate Na salt, Lamepon® UD (protein / undecylenic acid condensate), zinc pyrithione, aluminum pyrithione, and magnesium pyrithione / dipyrithione magnesium sulfate.

[0306] (Metal) chelating agents: The cosmetic or pharmaceutical compositions according to the present invention can be advantageously used in combination with one or more (metal) chelating agents, and any suitable or conventional metal chelating agent for cosmetic or pharmaceutical applications can be used. Preferred (metal) chelating agents include α-hydroxy fatty acids, phytic acid, lactoferrin, α-hydroxy acids, such as, inter alia, gluconic acid, glyceric acid, glycolic acid, isocitric acid, citric acid, lactic acid, malic acid, mandelic acid, tartaric acid, as well as humic acid, bile acids, bile extracts, bilirubin, biliverdin, or EDTA, EGTA, and derivatives thereof. The use of one or more chelating agents improves the stability of the compositions according to the present invention.

[0307] Emulsifiers: Furthermore, the cosmetic or pharmaceutical compositions according to the invention may advantageously also contain one or more emulsifiers, including, for example: - Linear C of 2 to 30 mol of ethylene oxide and / or 0 to 5 mol of propylene oxide 8~22 Fatty alcohol, C 12~22 Addition products of fatty acids and alkylphenols containing 8 to 15 carbon atoms in the alkyl group, - C of the adduct of 1 to 30 mol of ethylene oxide to glycerol 12 / 18 fatty acid monoesters and diesters, - glycerol mono- and diesters and sorbitan mono- and diesters of saturated and unsaturated fatty acids containing 6 to 22 carbon atoms, and their ethylene oxide adducts; - adducts of 15 to 60 mol of ethylene oxide onto castor oil and / or hydrogenated castor oil, - polyol esters, in particular polyglycerol esters, such as polyglycerol polyricinoleate, polyglycerol poly-12-hydroxystearate or polyglycerol dimerate isostearate. Mixtures of compounds from several of these classes are also suitable. - adducts of 2 to 15 mol of ethylene oxide onto castor oil and / or hydrogenated castor oil, - Linear, branched, unsaturated or saturated C 6 / 22 partial esters based on fatty acids, ricinoleic acid and 12-hydroxystearic acid, and glycerol, polyglycerol, pentaerythritol, dipentaerythritol, sugar alcohols (e.g. sorbitol), alkyl glucosides (e.g. methyl glucoside, butyl glucoside, lauryl glucoside) and polyglucosides (e.g. cellulose); mono-, di- and tri-alkyl phosphates and mono-, di- and / or tri-PEG-alkyl phosphates and salts thereof; - wool wax alcohol, - polysiloxane / polyalkylpolyether copolymers and corresponding derivatives, - Pentaerythritol, fatty acids, citric acid and fatty alcohols and / or C 6~22 mixed esters of fatty acids, methyl glucose and polyols, preferably glycerol or polyglycerol; polyalkylene glycols, and - Glycerol carbonate.

[0308] The addition products of ethylene oxide and / or propylene oxide to fatty alcohols, fatty acids, alkylphenols, glycerol mono- and diesters and sorbitan mono- and diesters of fatty acids, or to castor oil, are known commercially available products. These are homolog mixtures whose average degree of alkoxylation corresponds to the ratio between the amount of ethylene oxide and / or propylene oxide and the amount of substrate with which the addition reaction is carried out. The C of the addition of ethylene oxide to glycerol 12 / 18 Fatty acid mono- and diesters are known as lipid layer enhancers in cosmetic formulations. Preferred emulsifiers are described in more detail below.

[0309] Partial glycerides: Typical examples of suitable partial glycerides are hydroxystearic acid monoglyceride, hydroxystearic acid diglyceride, isostearic acid monoglyceride, isostearic acid diglyceride, oleic acid monoglyceride, oleic acid diglyceride, ricinoleic acid monoglyceride, ricinoleic acid diglyceride, linoleic acid monoglyceride, linoleic acid diglyceride, linolenic acid monoglyceride, linolenic acid diglyceride, erucic acid monoglyceride, erucic acid diglyceride, tartaric acid monoglyceride, tartaric acid diglyceride, citric acid monoglyceride, citric acid diglyceride, malic acid monoglyceride, malic acid diglyceride, and technical mixtures thereof which may further contain small amounts of triglycerides from the production process. Also suitable are addition products of 1 to 30, preferably 5 to 10, mol of ethylene oxide onto the mentioned partial glycerides.

[0310] Sorbitan esters: Suitable sorbitan esters include sorbitan monoisostearate, sorbitan sesquiisostearate, sorbitan diisostearate, sorbitan triisostearate, sorbitan monooleate, sorbitan sesquioleate, sorbitan dioleate, sorbitan trioleate, sorbitan monoerucate, sorbitan sesquierucate, sorbitan dierucate, sorbitan trierucate, sorbitan monoricinoleate, sorbitan sesquiricinoleate, sorbitan diricinoleate, sorbitan triricinoleate, sorbitan esters ... Suitable sorbitan esters include sorbitan monohydroxystearate, sorbitan sesquihydroxystearate, sorbitan dihydroxystearate, sorbitan trihydroxystearate, sorbitan monotartrate, sorbitan sesquitartrate, sorbitan ditartrate, sorbitan tritartrate, sorbitan monocitrate, sorbitan sesquicitrate, sorbitan dicitrate, sorbitan tricitrate, sorbitan monomaleate, sorbitan sesquimaleate, sorbitan dimaleate, sorbitan trimaleate, and technical mixtures thereof. Also suitable are addition products of 1 to 30, preferably 5 to 10, mol of ethylene oxide onto the aforementioned sorbitan esters.

[0311] Polyglycerol esters: Representative examples of suitable polyglycerol esters are polyglyceryl-2 dipolyhydroxystearate (Dehymuls® PGPH), polyglycerin-3-diisostearate (Lameform® TGI), polyglyceryl-4 isostearate (Isolan® GI 34), polyglyceryl-3 oleate, diisostearoyl polyglyceryl-3 diisostearate (Isolan® PDI), polyglyceryl-3 methylglucose distearate (Tego Care® 450), polyglyceryl-3 beeswax (Cera Bellina®), polyglyceryl-4 caprate (Polyglycerol Caprate T2010 / 90), polyglyceryl-3 cetyl ether (Chimexane® NL), polyglyceryl-3 distearate (Cremophor® GS32), polyglyceryl polyricinoleate (Admul® WOL1403), polyglyceryl dimerate isostearate and mixtures thereof. Examples of other suitable polyol esters are the mono-, di- and triesters of trimethylolpropane or pentaerythritol with lauric acid, coconut fatty acids, tallow fatty acids, palmitic acid, stearic acid, oleic acid, behenic acid, etc., optionally reacted with 1 to 30 mol of ethylene oxide.

[0312] Anionic emulsifiers: Representative anionic emulsifiers are aliphatic C12-C22 fatty acids, such as palmitic acid, stearic acid or behenic acid, and C12-C22 dicarboxylic acids, such as azelaic acid or sebacic acid.

[0313] Amphoteric emulsifiers: Other suitable emulsifiers are amphoteric or zwitterionic surfactants. Zwitterionic surfactants are surface-active compounds containing at least one quaternary ammonium group and at least one carboxylate group and one sulfonate group in the molecule. Particularly suitable zwitterionic surfactants are so-called betaines, such as N-alkyl-N,N-dimethylammonium glycinates, e.g., cocoalkyldimethylammonium glycinate, N-acylaminopropyl-N,N-dimethylammonium glycinates, e.g., cocoacylaminopropyldimethylammonium glycinate, and 2-alkyl-3-carboxymethyl-3-hydroxyethyl imidazolines containing 8 to 18 carbon atoms in the alkyl or acyl group, and cocoacylaminoethyl hydroxyethyl carboxymethyl glycinate. Fatty acid amide derivatives of cocamidopropyl betaine, known by the CTFA name, are particularly preferred. Amphoteric surfactants are also suitable emulsifiers. Amphoteric surfactants include C 8 / 18 These surfactants are surfactants that contain, in addition to alkyl or acyl groups, at least one free amino group and at least one -COOH- or -SO3H- group in the molecule and are capable of forming an intramolecular salt. Examples of suitable amphoteric surfactants are N-alkylglycines, N-alkylpropionic acids, N-alkylaminobutyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidopropylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids, and alkylaminoacetic acids containing about 8 to 18 carbon atoms in the alkyl group. Particularly preferred amphoteric surfactants are N-cocoalkylaminopropionates, cocoacylaminoethylaminopropionates, and C 12 / 18 It is an acyl sarcosine.

[0314] Surfactants: The cosmetic or pharmaceutical composition according to the invention preferably comprises one or more anionic and / or amphoteric or zwitterionic surfactants. Typical examples include: almondamidopropylamine oxide, almondamidopropyl betaine, aminopropyl lauryl glutamine, C12-15 ammonium alkyl sulfate, C12-16 ammonium alkyl sulfate, ammonium capryleth sulfate, coco monoglyceride ammonium sulfate, ammonium coco-sulfate, ammonium cocoyl isethionate, ammonium cocoyl sarcosinate, C12-15 ammonium pareth sulfate, C9-10 ammonium perfluoroalkyl sulfonate, ammonium dinonyl sulfosuccinate, ammonium dodecylbenzenesulfonate, ammonium isostearate, ammonium laureth-6 carboxylate, ammonium laureth-8 carboxylate, ammonium laureth sulfate, ammonium laureth-5 sulfate, ammonium laureth-7 sulfate, ammonium laureth-9 sulfate, ammonium laureth-12 sulfate, ammonium lauroyl sarcosinate, ammonium lauryl sulfate, ammonium lauryl sulfosuccinate, ammonium myreth sulfate, myreth sulfate, myristate ... Ammonium stearate, nonoxynol-4 ammonium sulfate, nonoxynol-30 ammonium sulfate, ammonium oleate, ammonium palm kernel sulfate, ammonium stearate, ammonium tallow, AMPD-isostearoyl hydrolyzed collagen, AMPD-rosin hydrolyzed collagen, AMP-isostearoyl hydrolyzed collagen, AMP-isostearoyl hydrolyzed keratin, AMP-isostearoyl hydrolyzed soy protein, AMP-isostearoyl hydrolyzed wheat protein Ingredients: Apricotamidopropyl Betaine, Arachidic Acid, Arginine Hexyldecyl Phosphate, Avocadoamidopropyl Betaine, Avocado Oil Glycereth-8 Ester, Babassu Acid, Babassuamidopropylamine Oxide, Babassuamidopropyl Betaine, Beeswax Acid, Behenamidopropyl Betaine, Behenamine Oxide, Beheneth-25, Beheneth-30, Behenic Acid, Behenyl Betaine, Bis-Butyl Dimethicone Polyglyceryl-3, Butoxynol-5 Carboxylic Acid, Butoxynol-19 Carboxylic Acid,Butyldimonium Hydroxypropyl Butylglucoside Chloride, Butyldimonium Hydroxypropyl Laurylglucoside Chloride, Butyl Glucoside, Butyl Glucoside Caprate, Butyl Glucoside Hydroxypropyltrimonium Chloride, Butyloctanoic Acid, C18-36 Acids, C20-40 Acids, C30-50 Acids, C16-22 Acid Amide MEA, Calcium Dodecylbenzenesulfonate, Calcium Lauroyl Taurate, C9-16 Alkane / Cycloalkane, C10-14 Alkylbenzenesulfonic Acid, C12-14 Alkyldiaminoethylglycine HCl, C9-15 Alkylphosphate, Candida Bombicola / Glucose / Rapeseed Oil Methyl Ferment, Canolamidopropyl Betaine, Capric Acid, Caproic Acid, Caproyl Ethyl Glucoside, Caprylic / Capramidopropyl Betaine, Capryleth-4 Carboxylic Acid, Capryleth-6 Carboxylic Acid, Capryleth-9 Carboxylic Acid, Capryloyl Collagen Amino Acids, Capryloyl Glycine, Capryloyl Hydrolyzed Collagen, Capryloyl Hydrolyzed Keratin, Capryloyl Keratin Amino Acids, Capryloyl Silk Amino Acids, Caprylyl / Capryl Glucoside, Caprylyl / Capryl Wheat Bran / Strawberry Glycoside, Caprylyl Glucoside, Caprylyl Glyceryl Ether, Caprylyl Pyrrolidone, Carnitine, Ceteareth-20, Ceteareth-23, Ceteareth-24, Se Teareth-25, Ceteareth-27, Ceteareth-28, Ceteareth-29, Ceteareth-30, Ceteareth-33, Ceteareth-34, Ceteareth-40, Ceteareth-50, Ceteareth-55, Ceteareth-60, Ceteareth-80, Ceteareth-100, Ceteareth-25 carboxylic acid, Ceteareth-2 phosphate, Ceteareth-4 phosphate, Ceteareth-5 phosphate Phosphate, Ceteareth-10 Phosphate, Ceteth-20, Ceteth-23, Ceteth-24, Ceteth-25, Ceteth-30, Ceteth-40, Ceteth-45, Ceteth-150, Ceteth-8 Phosphate, Ceteth-10 Phosphate, Ceteth-20 Phosphate, Cetoleth-22, Cetoleth-24, Cetoleth-25, Cetoleth-30, Cetyl Betaine, Chrysanthemum Sinense Flower Extract, C12-14 Hydroxyalkyl Hydroxyethyl Beta-Alanine,, C12-14 Hydroxyalkyl Hydroxyethyl Sarcosine, Cocamidoethyl Betaine, Cocamidopropyl Amine Oxide, Cocamidopropyl Betaine Amide MEA Chloride, Cocamidopropyl Betaine, Cocamidopropyl Hydroxysultaine, Cocamine Oxide, Cocaminobutyric Acid, Cocaminopropionic Acid, Coceth-7 Carboxylic Acid, Coceth-4 Glucoside, Cocoamphodipropionic Acid, Cocobetaine Amido Amphopropionate, Cocobetaine, Cocodimonium Hydroxypropyl Hydrolyzed Rice Protein, Cocodimonium Hydroxypropyl Hydrolyzed Hydrolyzed Soy Protein, Cocodimonium Hydroxypropyl Hydrolyzed Wheat Protein, Coco-Glucoside, Coco-Glucoside Hydroxypropyltrimonium Chloride, Coco-Hydroxysultaine, Coco-Morpholine Oxide, Coconut Fatty Acids, Coconut Oil Glycereth-8 Esters, Coco / Oleamidopropyl Betaine, Coco-Sultaine, Coco / Sunflower Amidopropyl Betaine, Cocoyl Choline Methosulfate, Cocoyl Glutamic Acid, Cocoyl Hydrolyzed Collagen, Cocoyl Hydrolyzed Keratin, Cocoyl Hydrolyzed Oat Protein, Cocoyl Hydrolyzed Cometa Protein, cocoyl hydrolyzed silk, cocoyl hydrolyzed soy protein, cocoyl hydrolyzed wheat protein, cocoyl sarcosine, corn acid, cottonseed acid, cottonseed oil glyceryl-8 ester, C10-16 Pareth-1, C10-16 Pareth-2, C11-13 Pareth-6, C11-13 Pareth-9, C11-13 Pareth-10, C11-15 Pareth-30, C11-15 Pareth-40, C12-13 Pareth-1, C12-13 Pareth-23, C12-14 Pareth-5, C12-14 Pareth-9, C13-15 Pareth-21, C14-15 Pareth-8, C20- 22 Palace-30, C20~40 Palace-40, C20~40 Palace-95, C22~24 Palace-33, C30~50 Palace-40, C9~11 Palace-6 carboxylic acid, C9~11 Palace-8 carboxylic acid, C11~15 Palace-7 carboxylic acid, C12~13 Palace-5 carboxylic acid, C12~13 Palace-7 carboxylic acid, C12~13 Palace-8 carboxylic acid, C12~13 Palace-12 carboxylic acid, C12~15 Palace-7 carboxylic acid, C12~15 Palace-8 carboxylic acid, C12~15 Palace-12 carboxylic acid, C14~15 Palace-8 carboxylic acid,C6~10 Pareth-4 phosphate, C12~13 Pareth-2 phosphate, C12~13 Pareth-10 phosphate, C12~15 Pareth-6 phosphate, C12~15 Pareth-8 phosphate, C12~15 Pareth-10 phosphate, C12~16 Pareth-6 phosphate, C4~18 perfluoroalkylethylthiohydroxypropyltrimonium chloride, cupuasamidopropyl betaine, DEA-C12~13 alkyl sulfate, DEA-C12~15 alkyl sulfate, DEA-ceteareth-2 phosphate, DEA-Cetyl Sulfate, DEA-Cocoamphodipropionate, DEA-C12-13 Pareth-3 Sulfate, DEA-Cyclocarboxypropyloleate, DEA-Dodecylbenzenesulfonate, DEA-Isostearate, DEA-Laureth Sulfate, DEA-Lauryl Sulfate, DEA-Linoleate, DEA-Methylmyristate Sulfonate, DEA-Myreth Sulfate, DEA-Myristate, DEA-Myristyl Sulfate, DEA-Oleth-5 Phosphate, DEA-Oleth-20 Phosphate, DEA PG-oleate, deceth-7 carboxylic acid, deceth-7 glucoside, deceth-9 phosphate, decylamine oxide, decyl betaine, decyl glucoside, decyltetradeceth-30, decyltetradecylamine oxide, diammonium lauramide-MEA sulfosuccinate, diammonium lauryl sulfosuccinate, diammonium oleamide PEG-2 sulfosuccinate, dibutoxymethane, di-Cl 2~15 pareth-2 phosphate, di-Cl 2~15 pareth-4 phosphate, di-Cl 2~15 pareth-6 phosphate, di-C12~15 pareth-8 phosphate, di-Cl 2-15 Pareth-10 Phosphate, Didodecyl Butane Tetracarboxylate, Diethylamine Laureth Sulfate, Diethylhexyl Sodium Sulfosuccinate, Dihydroxyethyl C8-10 Alkoxypropylamine Oxide, Dihydroxyethyl C9-11 Alkoxypropylamine Oxide, Dihydroxyethyl C12-15 Alkoxypropylamine Oxide, Dihydroxyethyl Cocamine Oxide, Dihydroxyethyl Lauramine Oxide, Dihydroxyethyl Stearamine Oxide,Dihydroxyethyl tallow amine oxide, dimethicone PEG-7 phosphate, dimethicone PEG-10 phosphate, Dimethicone PEG / PPG-7 / 4 Phosphate, Dimethicone PEG / PPG-12 / 4 Phosphate, Dimethicone / Polyglycerin-3 Crosspolymer, Dimethicone Propyl PG-Betaine, Dimyristyl Phosphate, Dioleoylamidoethyl Hydroxyethylmonium Methosulfate, DIPA-Hydrogenated Cocoate, DIPA-Lanolate, DIPA-Myristate, Dipotassium Capryloyl Glutamate, Dipotassium Lauryl Sulfosuccinate, Undecylenoyl Glutamate Dipotassium Sulfosuccinate, Babassuamide MEA-Disodium Sulfosuccinate, Disodium Caproamphodiacetate, Disodium Caproamphodipropionate, Disodium Capryloamphodiacetate, Disodium Capryloamphodipropionate, Disodium Capryloyl Glutamate, Disodium Cetearyl Sulfosuccinate, Disodium Cetyl Phenyl Ether Disulfonate, Disodium Cetyl Sulfosuccinate, Cocamide MEA-Disodium Sulfosuccinate, Cocamide MIPA PEG-4 Disodium Sulfosuccinate, Cocamide MIPA-Disodium Sulfosuccinate, Cocamide PEG-3 Disodium Sulfosuccinate, Coceth-3 Disodium Sulfosuccinate, Cocoamphocarboxyethyl Hydroxypropyl Sulfonate Disodium, Cocoamphodiacetate Disodium, Cocoamphodipropionate Disodium, Coco-Glucoside Sulfosuccinate Disodium, Coco-Sulfosuccinate Disodium, Cocoyl Butyl Gluceth-10 Sulfosuccinate Disodium, Cocoyl Glutamate Disodium, C12-14 Pareth-1 Disodium Sulfosuccinate, C12-14 Pareth-2 Disodium Sulfosuccinate, C12-15 Pareth-3 Disodium Sulfosuccinate, C12-14 Sec-Pareth-5 Disodium Sulfosuccinate, C12-14 Disodium Sec-Palace-7 Sulfosuccinate, Disodium C12-14 Sec-Palace-9 Sulfosuccinate, Disodium C12-14 Sec-Palace-12 Sulfosuccinate, Disodium Deceth-5 Sulfosuccinate, Disodium Deceth-6 Sulfosuccinate, Disodium Decyl Phenyl Ether Disulfonate, Disodium Dihydroxyethyl Sulfosuccinylundecylenate,Ethylenedicocamide PEG-15 disodium disulfate, hydrogenated cottonseed glyceride disodium sulfosuccinate, hydrogenated beef tallow disodium glutamate, hydroxydecyl sorbitol disodium citrate, isodecyl disodium sulfosuccinate, isostearamide MEA disodium sulfosuccinate, isostearamide MIPA disodium sulfosuccinate, isostearoamphodiacetate disodium, isostearoamphodipropionate disodium, isostearyl disodium sulfosuccinate, Laneth-5 disodium sulfosuccinate, lauramide Disodium MEA-Sulfosuccinate, Lauramide MIPA Glycol Sulfosuccinate, Disodium Lauramide PEG-2 Sulfosuccinate, Disodium Lauramide PEG-5 Sulfosuccinate, Disodium Laureth-5 Carboxyamphodiacetate, Disodium Laureth-7 Citrate, Disodium Laureth Sulfosuccinate, Disodium Laureth-6 Sulfosuccinate, Disodium Laureth-9 Sulfosuccinate, Disodium Laureth-12 Sulfosuccinate, Disodium Lauriminobishydroxypropylsulfonate, Disodium Lauriminobisacetic Acid Disodium Lauryl Phosphate, Disodium Lauryl Phosphate, Disodium Lauryl Phosphate, Disodium Lauroamphodiacetate, Disodium Lauroamphodipropionate, Disodium N-Lauroyl Aspartate, Disodium Lauroyl Glutamate, Disodium Lauryl Phenyl Ether Disulfonate, Disodium Lauryl Sulfosuccinate, Disodium Myristamide MEA-Sulfosuccinate, Disodium Nonoxynol-10 Sulfosuccinate, Disodium Oleamide MEA-Sulfosuccinate, Disodium Oleamide Disodium MIPA-Sulfosuccinate, Oleamide PEG-2 Sulfosuccinate, Disodium Oleoamphodipropionate, Disodium Oleth-3 Sulfosuccinate, Disodium Oleyl Phosphate, Disodium Oleyl Sulfosuccinate, Palmitamide PEG-2 Sulfosuccinate, Disodium Palmitreamide PEG-2 Sulfosuccinate, PEG-4 Cocamide MIPA Sulfosuccinate, Disodium PEG-12 Dimethicone Sulfosuccinate, Disodium Palm Fatty Acid PEG-8 Glycerides Sulfosuccinate,PPG-2-Isodeceth-7 Carboxyamphodiacetate Disodium, Ricinoleamide MEA Sulfosuccinate Disodium, Sitostereth-14 disodium sulfosuccinate, soy amphodiacetate disodium, stearamide MEA disodium sulfosuccinate, stearimidinone dipropionate disodium, stearoamphodiacetate disodium, stearoyl glutamate disodium, stearyl sulfosuccinamic acid disodium, stearyl sulfosuccinamic acid disodium, 2-sulfolauric acid disodium, 2-sulfopalmitic acid disodium, talamide MEA disodium sulfosuccinate, tallowamide MEA disodium sulfosuccinate, tallowamphodiacetate disodium, tallowiminodipropionate disodium, tallow sulfosuccinamic acid disodium, tridecyl sulfosuccinate disodium, undecylenamide MEA disodium sulfosuccinate, undecylenamide PEG-2 disodium sulfosuccinate, undecylenamide Disodium Decylenoyl Glutamate, Wheat Germ MEA Sulfosuccinate Disodium, Wheat Germ PEG-2 Sulfosuccinate Disodium, Wheat Germ Amphodiacetate Disodium, Di-TEA-Cocamide Diacetate, Di-TEA-Oleamide PEG-2 Sulfosuccinate, Di-TEA-Palmitoyl Aspartate, Sodium Ditridecyl Sulfosuccinate, Dodecyl Benzene Sulfonic Acid, Erucamidopropyl Hydroxysultaine, Ethylhexyl-3 Carboxylate, Ethyl PEG-15 Cocamine Sulfate, Glyceryl Caprylyl Ether, Hexyldecanoic Acid, Hydrogenated Coconut Fatty Acid, Hydrogenated Laneth-25, Hydrogenated Menhaden Acid, Hydrogenated Palm Acid, Hydrogenated Palm Kernel Amine Oxide, Hydrogenated Tallow Fatty Acid, Hydrogenated Tallow Amine Oxide, Hydrogenated Tallow Betaine, Hydrogenated Tallow Wes-25, Hydrogenated Tallow Oil Glutamic Acid, Hydrolyzed Candida Bombicola Extract, Hydroxyceteth-60, Hydroxyethylacetemonium PG-Dimethicone, Hydroxyethylbutylamine Laureth Sulfate, Hydroxyethylcarboxymethylcocamidopropylamine, Hydroxyethylhydroxypropyl C12-15 Alkoxypropylamine Oxide, Hydroxylauryl / Hydroxymyristyl Betaine, Hydroxystearic Acid, Hydroxysuccinimidyl C10-40 Isoalkyl Acidate, Hydroxysuccinimidyl C21-22 Isoalkyl Acidate, HydroxysultaineIPDI / PEG-15 Soyamine Oxide Copolymer, IPDI / PEG-15 Soyethonium Ethosulfate Copolymer, IPDI / PEG-15 Soy Glycinate Copolymer, Isoceteth-30, Isolaureth-4 Phosphate, Isopolyglyceryl-3 Dimethicone, Isopolyglyceryl-3 Dimethiconol, Isopropanolamine Lanolate, Isopropylamine Dodecylbenzenesulfonate, Isostearamidopropylamine Oxide, Isostearamidopropyl Betaine, Isostearamidopropyl Morpholine Oxide, Isostearamidopropyl Isosteareth-8, Isosteareth-16, Isosteareth-22, Isosteareth-25, Isosteareth-50, Isostearic Acid, Isostearoyl Hydrolyzed Collagen, Jojoba Oil PEG-150 Ester, Jojoba Wax PEG-80 Ester, Jojoba Wax PEG-120 Ester, Laneth-20, Laneth-25, Laneth-40, Laneth-50, Laneth-60, Laneth-75, Lanolinic Acid, Lauramidopropylamine Oxide, Lauramidopropyl Betaine, Lauramidopropyl Hydroxysultaine, Lauramine Oxide, Lauraminopropionic Acid, La Urdimonium hydroxypropyl decyl glucoside chloride, laurdimonium hydroxypropyl lauryl glucoside chloride, laureth-16, laureth-20, laureth-21, laureth-23, laureth-25, laureth-30, laureth-38, laureth-40, laureth-3 carboxylic acid, laureth-4 carboxylic acid, laureth-5 carboxylic acid, laureth-6 carboxylic acid, laureth-8 carboxylic acid, laureth-10 carboxylic acid, laureth-11 carboxylic acid, laureth-12 carboxylic acid, laureth-13 carboxylic acid, laureth-14 carboxylic acid, Laureth-17 Carboxylic Acid, Laureth-6 Citric Acid, Laureth-7 Citric Acid, Laureth-1 Phosphate, Laureth-2 Phosphate, Laureth-3 Phosphate, Laureth-4 Phosphate, Laureth-7 Phosphate, Laureth-8 Phosphate, Laureth-7 Tartaric Acid, Lauryl Acid, Lauriminobispropanediol, Lauriminodipropionic Acid, Lauroamphodipropionic Acid, Lauroyl Beta-Alanine, Lauroyl Collagen Amino Acids, Lauroyl Ethyltrimonium Methosulfate, Lauroyl Hydrolyzed Collagen, Lauroyl Hydrolyzed Elastin, Lauroyl Methylglucamide,Lauroyl Sarcosine, Lauroyl Silk Amino Acids, Lauryl Betaine, Lauryl Dimethicone / Polyglycerin-3 Crosspolymer, Lauryldimonium Hydroxypropyl Coco-Glucoside Chloride, Lauryl Glucoside, Lauryl Glucoside Hydroxypropyltrimonium Chloride, Lauryl Glycol Hydroxypropyl Ether, Lauryl Hydroxysultaine, Lauryl Malamide, Lauryl Methyl Glucamide, Lauryl / Myristyl Glycol Hydroxypropyl Ether, Lauryl / Myristyl Wheat Bran / Straw Glycoside, Lauryl Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Lauryl Pyrrolidone, Lauryl Sultaine, Linoleic Acid, Linolenic Acid, Flaxseed Acid, Coco-Lysine, Macadamia Seed Oil Glycereth-8 Esters, Magnesium Coceth Sulfate, Magnesium Coco-Sulfate Magnesium, Magnesium Isododecylbenzenesulfonate, Magnesium Laureth-11 Carboxylate, Magnesium Laureth Sulfate, Magnesium Laureth-5 Sulfate, Magnesium Laureth-8 Sulfate, Magnesium Laureth-16 Sulfate, Magnesium Laureth-3 Sulfosuccinate, Magnesium Lauryl Hydroxypropyl Sulfonate, Magnesium Lauryl Sulfate, Magnesium Methyl Cocoyl Taurate, Magnesium Myreth Sulfate, Magnesium Oleth Sulfate, Magnesium / TEA-Cocosulfate, Maniquagang Clay, MEA-Cocoate, MEA-Laureth-6 Carboxylate, MEA-Laureth Sulfate, MEA-Lauryl Sulfate, MEA PPG-6 laureth-7 carboxylate, MEA-PPG-8-steareth-7 carboxylate, MEA-undecylenate, meroxapol 108, meroxapol 174, meroxapol 178, meroxapol 254, meroxapol 255, meroxapol 258, meroxapol 314, methoxy PEG-450 amido glutaroyl succinimide, methoxy PEG-450 amido hydroxysuccinimidyl succinamate, methoxy PEG-450 maleimide, methylmorpholine oxide, milk amidopropylamine oxide, milk amidopropyl betaine, mincamidopropylamine oxide, mincamidopropyl betaine, MIPA C12-15 pareth sulfate, MIPA-dodecylbenzenesulfonate, MIPA-laureth sulfate, MIPA-lauryl sulfate, mixed isopropanolamine lanolate,Mixed isopropanolamine lauryl sulfate, mixed isopropanolamine myristate, morpholine oleate, morpholine stearate, myreth-3 carboxylic acid, myreth-5 carboxylic acid, myristalkonium chloride, myristamidopropylamine oxide, myristamidopropyl betaine, myristamidopropyl dimethylamine phosphate, myristamidopropyl hydroxysultaine, myristamidopropyl PG-dimonium chloride phosphate, myristaminopropionic acid, myristic acid, myristoyl ethoxylate Tyltrimonium methosulfate, myristoyl glutamic acid, myristoyl hydrolyzed collagen, myristoyl sarcosine, myristyl betaine, myristyl / cetylamine oxide, myristyldimonium hydroxypropyl cocoglucoside chloride, myristyl glucoside, myristyl phosphate, nonoxynol-20, nonoxynol-23, nonoxynol-25, nonoxynol-30, nonoxynol-35, nonoxynol-40, nonoxynol-44, nonoxynol-50, nonoxynol-100, nonoxynol-12 0, nonoxynol-5 carboxylic acid, nonoxynol-8 carboxylic acid, nonoxynol-10 carboxylic acid, nonoxynol-3 phosphate, nonoxynol-4 phosphate, nonoxynol-6 phosphate, nonoxynol-9 phosphate, nonoxynol-10 phosphate, nonylnonoxynol-30, nonylnonoxynol-49, nonylnonoxynol-100, nonylnonoxynol-150, nonylnonoxynol-7 phosphate, nonylnonoxynol-8 phosphate, nonylnonoxynol-9 phosphate, nonylnonoxynol Noxynol-10 phosphate, nonylnonoxynol-11 phosphate, nonylnonoxynol-15 phosphate, nonylnonoxynol-24 phosphate, oat maltodextrin, octoxynol-16, octoxynol-25, octoxynol-30, octoxynol-33, octoxynol-40, octoxynol-70, octoxynol-20 carboxylic acid, octyldodeceth-20, octyldodeceth-25, octyldodeceth-30, oleamidopropylamine oxide, oleamidopropyl betaine,Oleamidopropyl hydroxysultaine, oleamine oxide, oleic acid, oleoyl hydrolyzed collagen, oleoyl sarcosine, oleth-20, Oleth-23, Oleth-24, Oleth-25, Oleth-30, Oleth-35, Oleth-40, Oleth-44, Oleth-50, Oleth-3 Carboxylic Acid, Oleth-6 Carboxylic Acid, Oleth-10 Carboxylic Acid, Oleyl Betaine, Olivamidopropylamine Oxide, Olivamidopropyl Betaine, Olivoyl Hydrolyzed Wheat Protein, Ophiopogon Extract Stearate, Ozonated Oleth-10, Ozonated PEG-10 Oleate, Ozonated PEG-14 Oleate, Ozonated Polysorbate 80, Palm Acid, Palmamidopropyl Betaine , Palmeth-2 Phosphate, Palmitamidopropylamine Oxide, Palmitamidopropyl Betaine, Palmitamine Oxide, Palmitic Acid, Palmitoyl Collagen Amino Acids, Palmitoyl Glycine, Palmitoyl Hydrolyzed Collagen, Palmitoyl Hydrolyzed Milk Protein, Palmitoyl Hydrolyzed Wheat Protein, Palmitoyl Keratin Amino Acids, Palmitoyl Oligopeptide, Palmitoyl Silk Amino Acids, Palm Nucleic Acid, Palmamidopropyl Betaine, Peach Kernel Oil Glycereth-8 Esters, Peanut Acid, PEG-10 Castor Oil, PEG- 40 Castor Oil, PEG-44 Castor Oil, PEG-50 Castor Oil, PEG-54 Castor Oil, PEG-55 Castor Oil, PEG-60 Castor Oil, PEG-80 Castor Oil, PEG-100 Castor Oil, PEG-200 Castor Oil, PEG-11 Cocamide, PEG-6 Cocamide Phosphate, PEG-4 Cocamine, PEG-8 Cocamine, PEG-12 Cocamine, PEG-150 Dibehenate, PEG-90 Diisostearate, PEG-75 Dilaurate, PEG-150 Dilaurate, PEG-75 Dioleate, PEG-150 Dioleate, PEG-75 Distearate Alkyl Acetate, PEG-120 Distearate, PEG-150 Distearate, PEG-175 Distearate, PEG-190 Distearate, PEG-250 Distearate, PEG-30 Glyceryl Cocoate, PEG-40 Glyceryl Cocoate, PEG-78 Glyceryl Cocoate, PEG-80 Glyceryl Cocoate, PEG-30 Glyceryl Isostearate, PEG-40 Glyceryl Isostearate, PEG-50 Glyceryl Isostearate, PEG-60 Glyceryl Isostearate, PEG-90 Glyceryl Isostearate,PEG-23 Glyceryl Laurate, PEG-30 Glyceryl Laurate, PEG-25 Glyceryl Oleate, PEG-30 Glyceryl Oleate, PEG-30 Glyceryl Soyate, PEG-25 Glyceryl Stearate, PEG-30 Glyceryl Stearate, PEG-40 Glyceryl Stearate, PEG-120 Glyceryl Stearate, PEG-200 Glyceryl Stearate, PEG-28 Glyceryl Tallowate, PEG-80 Glyceryl Tallowate, PEG-82 Glyceryl Tallowate, PEG-130 Glyceryl Tallowate, Beef Fat PEG-200 Glyceryl Acetate, PEG-45 Hydrogenated Castor Oil, PEG-50 Hydrogenated Castor Oil, PEG-54 Hydrogenated Castor Oil, PEG-55 Hydrogenated Castor Oil, PEG-60 Hydrogenated Castor Oil, PEG-80 Hydrogenated Castor Oil, PEG-100 Hydrogenated Castor Oil, PEG-200 Hydrogenated Castor Oil, PEG-30 Hydrogenated Lanolin, PEG-70 Hydrogenated Lanolin, PEG-50 Hydrogenated Palmamide, PEG-2 Isostearate, PEG-3 Isostearate, PEG-4 Isostearate, PEG-6 Isostearate, PEG-8 Isostearate, PEG-10 Isostearate, PEG- 12 Isostearate, PEG-20 Isostearate, PEG-30 Isostearate, PEG-40 Isostearate, PEG-26 Jojoba Acid, PEG-40 Jojoba Acid, PEG-15 Jojoba Alcohol, PEG-26 Jojoba Alcohol, PEG-40 Jojoba Alcohol, PEG-35 Lanolin, PEG-40 Lanolin, PEG-50 Lanolin, PEG-55 Lanolin, PEG-60 Lanolin, PEG-70 Lanolin, PEG-75 Lanolin, PEG-85 Lanolin, PEG-100 Lanolin, PEG-150 Lanolin, PEG-75 Lanolin Oil, PEG -2 Lauramide, PEG-3 Lauramine Oxide, PEG-20 Laurate, PEG-32 Laurate, PEG-75 Laurate, PEG-150 Laurate, PEG-70 Mango Seed Oil Glycerides, PEG-20 Mannitan Laurate, PEG-8 Methyl Ether Dimethicone, PEG-120 Methyl Glucose Dioleate, PEG-80 Methyl Glucose Laurate, PEG-120 Methyl Glucose Trioleate, PEG-4 Montanate, PEG-30 Oleamine, PEG-20 Oleate, PEG-23 Oleate, PEG-32 Oleate,PEG-36 oleate, PEG-75 oleate, PEG-150 oleate, PEG-20 palmitate, PEG-150 Polyglyceryl-2 Tristearate, PEG / PPG-28 / 21 Acetate Dimethicone, PEG / PPG-24 / 18 Butyl Ether Dimethicone, PEG / PPG-3 / 17 Copolymer, PEG / PPG-5 / 35 Copolymer, PEG / PPG-8 / 55 Copolymer, PEG / PPG-10 / 30 Copolymer, PEG / PPG-10 / 65 Copolymer, PEG / PPG-12 / 35 Copolymer, PEG / PPG-16 / 17 Copolymer, PEG / PPG-20 / 9 Copolymer, PEG / PPG-20 / 20 Copolymer, PEG / PP G-20 / 60 copolymer, PEG / PPG-20 / 65 copolymer, PEG / PPG-22 / 25 copolymer, PEG / PPG-28 / 30 copolymer, PEG / PPG-30-35 copolymer, PEG / PPG-30 / 55 copolymer, PEG / PPG-35 / 40 copolymer, PEG / PPG-50 / 40 copolymer, PEG / PPG-150 / 35 copolymer, PEG / PPG-160 / 30 copolymer, PEG / PPG-190 / 60 copolymer, PEG / PPG-200 / 40 copolymer, PEG / PPG-300 / 55 copolymer, PEG / PPG-20 / 22 Methyl Ether Dimethicone, PEG-26-PPG-30 Phosphate, PEG / PPG-4 / 2 Propylheptyl Ether, PEG / PPG-6 / 2 Propylheptyl Ether, PEG-7 / PPG-2 Propylheptyl Ether, PEG / PPG-8 / 2 Propylheptyl Ether, PEG / PPG-10 / 2 Propylheptyl Ether, PEG / PPG-14 / 2 Propylheptyl Ether, PEG / PPG-40 / 2 Propylheptyl Ether, PEG / PPG-10 / 2 Ricinoleate, PEG / PPG-32 / 3 Ricinoleate PEG-55 Propylene Glycol Oleate, PEG-25 Propylene Glycol Stearate, PEG-75 Propylene Glycol Stearate, PEG-120 Propylene Glycol Stearate, PEG-5 Rapeseed Seed Sterol, PEG-10 Rapeseed Seed Sterol, PEG-40 Ricinoleamide, Shea Butter PEG-75 Glycerides, Shorea Butter PEG-75 Glycerides, PEG-20 Sorbitan Cocoate, PEG-20 Sorbitan Isostearate, PEG-40 Sorbitan Lanolate, PEG-75 Sorbitan Lanolate,PEG-10 Sorbitan Laurate, PEG-40 Sorbitan Laurate, PEG-44 Sorbitan Laurate, PEG-75 Sorbitan Laurate, PEG-80 Sorbitan Laurate, PEG-20 Sorbitan Oleate, PEG-80 Sorbitan Palmitate, PEG-40 Sorbitan Stearate, PEG-60 Sorbitan Stearate, PEG-160 Sorbitan Triisostearate, PEG-40 Soy Sterol, PEG-2 Stearamido Carboxylic Acid, PEG-9 Stearamido Carboxylic Acid, PEG-20 Stearate, PEG-23 Stearamido Carboxylic Acid Stearate, PEG-25 Stearate, PEG-30 Stearate, PEG-32 Stearate, PEG-35 Stearate, PEG-36 Stearate, PEG-40 Stearate, PEG-45 Stearate, PEG-50 Stearate, PEG-55 Stearate, PEG-75 Stearate, PEG-90 Stearate, PEG-100 Stearate, PEG-120 Stearate, PEG-150 Stearate, PEG-45 Stearate Phosphate, PEG-20 Stearate, PEG-50 Tallowamide, PEG-2 Tallowamide DEA, Beef Tallow PEG-20 Trihydroxystearin, PEG-66 Trihydroxystearin, PEG-200 Trihydroxystearin, Camellia Oil PEG-60 Glycerides, Pelargonic Acid, Pentadoxyl-200, Phenes-6 Phosphate, Poloxamer 105, Poloxamer 108, Poloxamer 182, Poloxamer 183, Poloxamer 184, Poloxamer 188, Poloxamer 217, Poloxamer 234, Poloxamer 235, Poloxamer 237, Poloxamer 238, Poloxamer 288, Poloxamer 334, Poloxamer 335, Poloxamer 338, Poloxamine 908, Poloxamine 1508, Polydimethylsiloxy PEG / PPG-24 / 19 Butyl Ether Silsesquioxane, Polydimethylsiloxy PPG-13 Butyl Ether Silsesquioxane, Polyglyceryl-6 Caprate, Polyglyceryl-10 Dilaurate, Polyglyceryl-20 Heptacaprylate, Polyglyceryl-20 Hexacaprylate, Polyglyceryl-2 Lauryl Ether, Polyglyceryl-10 Lauryl Ether, Polyglyceryl-20 Octaisononanoate, Polyglyceryl-6 Pentacaprylate,Polyglyceryl-10 Pentacaprylate, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Polyglyceryl-6 Tetracaprylate, Polyglyceryl-10 Tetralaurate, Polyglyceryl-6 Tricaprylate, Polyglyceryl-10 Trilaurate, Polyquaternium-77, Polyquaternium-78, Polyquaternium-79, Polyquaternium-80, Polyquaternium-81, Polyquaternium-82, Pomaderris Kumerahou Flower / Leaf Extract, Poria Cocos extract, potassium abitoyl hydrolyzed collagen, potassium babassuate, potassium behenate, potassium C9-15 alkyl phosphate, potassium C11-15 alkyl phosphate, potassium C12-13 alkyl phosphate, potassium C12-14 alkyl phosphate, potassium caprate, potassium capryloyl glutamate, potassium capryloyl hydrolyzed rice protein, potassium castor oil fatty acid, potassium coconut oil fatty acid, potassium cocoyl glutamate, potassium cocoyl glycinate, potassium cocoyl hydrolyzed casein, potassium cocoyl hydrolyzed collagen, potassium cocoyl hydrolyzed corn protein, potassium cocoyl hydrolyzed keratin, potassium cocoyl hydrolyzed oat protein, potassium cocoyl hydrolyzed potato protein, potassium cocoyl hydrolyzed rice bran protein, potassium cocoyl hydrolyzed rice protein, potassium cocoyl hydrolyzed silk, potassium cocoyl hydrolyzed soy protein Ingredients: Potassium cocoyl hydrolyzed wheat protein, potassium cocoyl hydrolyzed yeast protein, potassium cocoyl PCA, potassium cocoyl sarcosinate, potassium cocoyl taurate, potassium corn oil fatty acid, potassium cyclocarboxypropyl oleate, potassium dihydroxyethyl cocamine oxide phosphate, dimethicone PEG-7 potassium phosphate, potassium dodecylbenzenesulfonate, potassium hemp seed fatty acid, potassium hydrogenated coconut oil fatty acid, potassium hydrogenated palm fatty acid, potassium hydrogenated beef tallow fatty acid, potassium hydroxystearate, potassium isostearate, potassium lanolate, potassium laurate, potassium laureth-3 carboxylate, potassium laureth-4 carboxylate, potassium laureth-5 carboxylate, potassium laureth-6 carboxylate, potassium laureth-10 carboxylate, potassium laureth phosphate, potassium lauroyl collagen amino acids, potassium lauroyl glutamatePotassium lauroyl hydrolyzed collagen, potassium lauroyl hydrolyzed pea protein, potassium lauroyl hydrolyzed soy protein, potassium lauroyl PCA, potassium lauroyl pea amino acids, potassium lauroyl sarcosinate, potassium lauroyl silk amino acids, potassium lauroyl wheat amino acids, potassium lauryl phosphate, potassium lauryl sulfate, potassium linoleate, potassium metaphosphate, potassium methyl cocoyl taurate, potassium myristate, potassium myristoyl glutamate, potassium myristoyl hydrolyzed collagen, potassium octoxynol-12 phosphate, potassium oleate, potassium oleoyl hydrolyzed collagen, potassium olive oil fatty acids, potassium olivoyl hydrolyzed oat protein, potassium olivoyl hydrolyzed wheat protein, potassium olivoyl / lauroyl wheat amino acids, potassium olivoyl PCA, potassium palm fatty acids, potassium palmitate, potassium palmitoyl hydrolyzed corn protein, potassium palmitoyl hydrolyzed oat protein, potassium palmitoyl hydrolyzed palm Hydrolyzed rice protein potassium, palmitoyl hydrolyzed sweet almond protein potassium, palmitoyl hydrolyzed wheat protein potassium, potassium palm kernel acid, potassium peanut acid, rapeseed oil fatty acid potassium, potassium ricinoleate, safflower fatty acid potassium, potassium soyate, potassium stearate, stearoyl hydrolyzed collagen potassium, potassium tallate, beef tallow fatty acid potassium, potassium taurate, taurine potassium laurate, trideceth-3 carboxylic acid potassium, trideceth-4 carboxylic acid potassium, Potassium trideceth-7 carboxylate, potassium trideceth-15 carboxylate, potassium trideceth-19 carboxylate, potassium trideceth-6 phosphate, potassium trideceth-7 phosphate, potassium camellia acid, potassium undecylenate, potassium undecylenoyl hydrolyzed collagen, potassium undecylenoyl hydrolyzed rice protein, PPG-30-buteth-30, PPG-36-buteth-36, PPG-38-buteth-37, PPG-30-capryleth-4 phosphate, PPG-10 cetyl ether phosphate, PPG-2 C9~11 pareth-8, PPG-1-deceth-5, PPG-3-deceth-2 carboxylic acid,PPG-30 Ethylhexyl-4 Phosphate, PPG-20 Glycereth-30, PPG-2 Hydroxyethyl Coco / Isostearamide, PPG-2-Isodeceth-8, PPG-2-Isodeceth-10, PPG-2-Isodeceth-18, PPG-2-Isodeceth-25, PPG-4-Isodeceth-10, Propyltrimonium Hydrolyzed Collagen, Quaternium-24, Quaternium-52, Quaternium-87, Rapeseed Oil Fatty Acids, Rice Bran Acid, Rice Oil Glycereth-8 Ester, Ricinoleamidopropyl Betaine, Ricinoleic Acid, Ricinoleth-40, Safflower Acid, Sapindus Oahuensis Fruit Extract, Saponaria Officinalis Root Powder, Saponin, Soap-K, Soap-Na / K, Soap Base, Soap Base-K, Sesame Oil Glycereth-8 Ester, Sesamidopropylamine Oxide, Sesamidopropyl Betaine, Shea Butter Amidopropyl Betaine, Shea Butter Glycereth-8 Ester, Sodium Arachidate, Argan Sodium Amphoacetate, Astropotamus Murumuru Oil Sodium Fatty Acids, Sodium Avocado Acid, Babassu Sodium Amphoacetate, Sodium Babassuate, Babassu Sulfate, Sodium Behenate, Sodium Bisglycolicinosulfosuccinate, Sodium Bishydroxyethylglycinate Coco-glucoside Crosspolymer, Sodium Bishydroxyethylglycinate Lauryl-glucoside Crosspolymer, Borageamidopropyl PG-Dimonium Chloride Phosphate, Sodium Butoxynol-12 Sulfate, Butyl Gluconate Sodium cocoyl hydroxypropyl phosphate, sodium C13-17 alkane sulfonate, sodium C14-18 alkane sulfonate, sodium C12-15 alkoxypropyliminodipropionate, sodium C10-16 alkyl sulfate, sodium C11-15 alkyl sulfate, sodium C12-13 alkyl sulfate, sodium C12-15 alkyl sulfate, sodium C12-18 alkyl sulfate, sodium C16-20 alkyl sulfate, sodium C9-22 alkyl sec sulfonate, sodium C14-17 alkyl sec sulfonate, sodium caprate, sodium caproamphoacetate, sodium caproamphohydroxypropylsulfonate, sodium caproamphopropionate, sodium caproyl methyl taurate, sodium caprylate, sodium capryleth-2 carboxylate, sodium capryleth-9 carboxylateSodium capryloamphoacetate, sodium capryloamphohydroxypropylsulfonate, sodium capryloamphopropionate, sodium capryloyl glutamate, sodium capryloyl hydrolyzed wheat protein, sodium caprylyl PG-sulfonate, sodium caprylyl sulfonate, sodium castor oil, sodium ceteareth-13 carboxylate, sodium cetearyl sulfate, sodium ceteth-13 carboxylate, sodium cetyl sulfate, sodium cocamidopropyl PG-dimonium chloride phosphate, sodium cocaminopropionate, sodium coceth sulfate, sodium coceth-30 sulfate, sodium cocoamphoacetate, sodium cocoamphohydroxypropylsulfonate Sodium Cocoamphopropionate, Sodium Cocoate, Coco / Babasu / Andiloba Sulfate, Sodium Coco / Babasu Sulfate, Sodium Coco-Glucoside Hydroxypropyl Phosphate, Sodium Coco-Glucoside Hydroxypropyl Sulfonate, Sodium Coco-Glucoside Tartrate, Sodium Coco-Glyceryl Ether Sulfonate, Sodium Coco / Hydrogenated Tallow Sulfate, Sodium Cocoiminodiacetate, Sodium Coco Monoglyceride Sulfate, Sodium Coco Monoglyceride Sulfonate, Sodium Coco PG-Dimonium Chloride Phosphate, Sodium Coco Sulfate, Sodium Coco Sulfoacetate, Sodium Cocoyl Alanine Acid, Sodium Cocoyl Amino Acids, Sodium Cocoyl Collagen Amino Acids, Sodium Cocoyl Glutamate Cocoyl Glutamate, Sodium Cocoyl Glutamate, Sodium Cocoyl Glycinate, Cocoyl / Hydrogenated Beef Tallow Sodium Glutamate, Sodium Cocoyl Hydrolyzed Collagen, Sodium Cocoyl Hydrolyzed Keratin, Sodium Cocoyl Hydrolyzed Rice Protein, Sodium Cocoyl Hydrolyzed Silk, Sodium Cocoyl Hydrolyzed Soy Protein, Sodium Cocoyl Hydrolyzed Sweet Almond Protein, Sodium Cocoyl Hydrolyzed Wheat Protein, Sodium Cocoyl Hydrolyzed Wheat Protein Glutamate, Sodium Cocoyl Isethionate, Sodium Cocoyl Methylaminopropionate,Sodium cocoyl oat amino acids, sodium cocoyl / palmoyl / sunfloweroyl glutamate, sodium cocoyl proline, Sodium cocoyl sarcosinate, sodium cocoyl taurate, sodium cocoyl threonate, sodium cocoyl wheat amino acids, sodium C12-14 olefin sulfonate, sodium C14-16 olefin sulfonate, sodium C14-18 olefin sulfonate, sodium C16-18 olefin sulfonate, sodium corn amphopropionate, sodium cottonseed amphoacetate, sodium C13-15 pareth-8 butyl phosphate, sodium C9-11 pareth-6 carboxylate, sodium C11-15 pareth-7 carboxylate , C12~13 Pareth-5 Sodium Carboxylate, C12~13 Pareth-8 Sodium Carboxylate, C12~13 Pareth-12 Sodium Carboxylate, C12~15 Pareth-6 Sodium Carboxylate, C12~15 Pareth-7 Sodium Carboxylate, C12~15 Pareth-8 Sodium Carboxylate, C14~15 Pareth-8 Sodium Carboxylate, C12~14 Sec-Pareth-8 Sodium Carboxylate, C14~15 Pareth-PG Sodium Sulfonate, C12~13 Pareth-2 Sodium Phosphate, C13~15 Pareth-8 Sodium Phosphate, C9~1 5 Pareth-3 Sodium Sulfate, C10-15 Pareth-2 Sodium Sulfate, C10-16 Pareth-2 Sodium Sulfate, C12-13 Pareth-3 Sodium Sulfate, C12-15 Pareth-3 Sodium Sulfate, C12-15 Pareth-3 Sodium Sulfate, C13-15 Pareth-3 Sodium Sulfate, C12-14 Sec-Pareth-3 Sodium Sulfate, C12-15 Pareth-3 Sodium Sulfonate, C12-15 Pareth-7 Sodium Sulfonate, C12-15 Pareth-15 Sodium Sulfonate, Deceth-2 Sodium Carbonate, Deceth Sulfate, Decyl Benzene Sulfate Sodium benzoate, Sodium decyl glucoside hydroxypropyl phosphate, Sodium decyl glucoside hydroxypropyl sulfonate, Sodium dilaureth-7 citrate, Sodium dilaureth-10 phosphate, Sodium dilinoleate, Sodium dilinoleate, Sodium dioleth-8 phosphate, Sodium dodecylbenzenesulfonate, Sodium ethyl 2-sulfolaurate, Sodium glyceryl oleate phosphate, Sodium grapeseed amidopropyl PG-dimonium chloride phosphate,Sodium grapeseed amphoacetate, sodium grapeseed oil fatty acid, sodium hemp seed amphoacetate, sodium hexeth-4 carboxylate, hydrogenated sodium coconut oil fatty acid, hydrogenated sodium cocoyl methyl isethionate, hydrogenated sodium palm oil fatty acid, hydrogenated sodium tallow oil fatty acid, hydrogenated sodium tallow oil glutamate, sodium hydroxylauryldimonium ethyl phosphate, sodium hydroxypropyl palm kernel acid sulfonate, sodium hydroxypropyl phosphate decyl glucoside crosspolymer, sodium hydroxypropyl phosphate lauryl glucoside crosspolymer, sodium hydroxypropyl sulfonate coco-glucoside crosspolymer, sodium hydroxypropyl sulfonate decyl glucoside crosspolymer, sodium hydroxypropyl sulfonate lauryl glucoside crosspolymer, sodium hydroxypropyl sulfonate sodium lauryl glucoside crosspolymer, sodium hydroxystearate, sodium isostearate, sodium isosteareth-6 carboxylate, sodium isosteareth-11 carboxylate, sodium isostearoamphoacetate, sodium isostearoamphopropionate, N-isostearoyl methyl taurate Sodium, Sodium Laneth Sulfate, Sodium Lanolinate, Sodium Lardate, Sodium Lauramide Diacetate, Sodium Lauraminopropionate, Sodium Laurate, Sodium Laureth-3 Carboxylate, Sodium Laureth-4 Carboxylate, Sodium Laureth-5 Carboxylate, Sodium Laureth-6 Carboxylate, Sodium Laureth-8 Carboxylate, Sodium Laureth-11 Carboxylate, Sodium Laureth-12 Carboxylate, Sodium Laureth-13 Carboxylate, Sodium Laureth-14 Carboxylate, Sodium Laureth-16 Carboxylate, Sodium Laureth-17 Carboxylate, Sodium Laureth Sulfate, Sodium Laureth-5 Sulfate, Sodium Laureth-7 Sulfate, Sodium Laureth-8 Sulfate, Sodium Laureth-12 Sulfate, Sodium Laureth-40 Sulfate, Sodium Laureth-7 Tartrate, Sodium Lauraminodipropionate, Sodium Lauroamphoacetate, Sodium Lauroamphohydroxypropylsulfonate, Sodium Lauroampho PG-Acetate Phosphate, Sodium Lauroamphopropionate, Sodium Lauroyl AspartateSodium lauroyl collagen amino acids, sodium lauroyl glycine propionate, Sodium lauroyl hydrolyzed collagen, sodium lauroyl hydrolyzed silk, sodium lauroyl hydroxypropyl sulfonate, sodium lauroyl isethionate, sodium lauroyl methylaminopropionate, sodium lauroyl methyl isethionate, sodium lauroyl millet amino acid, sodium lauroyl / myristoyl aspartate, sodium lauroyl oat amino acid, sodium lauroyl sarcosinate, sodium lauroyl silk amino acid, sodium lauroyl taurate, sodium lauroyl wheat amino acid, sodium lauryl diethylenediaminoglycinate, sodium lauryl glucose carboxylate, sodium lauryl glucoside hydroxypropyl phosphate, sodium lauryl glucoside hydroxypropyl sulfonate, sodium lauryl glycol carboxylate, sodium lauryl hydroxyacetamide sulfate, sodium lauryl phosphate, sodium lauryl sulfate, sodium lauryl sulfoacetate, sodium linoleate, sodium macadamia seed oil fatty acid, sodium mango amphoacetate, sodium mango seed oil fatty acid Sodium / MEA Laureth-2 Sulfosuccinate, Sodium Methoxy PPG-2 Acetate, Sodium Methyl Cocoyl Taurate, Sodium Methyl Lauroyl Taurate, Sodium Methyl Myristoyl Taurate, Sodium Methyl Oleoyl Taurate, Sodium Methyl Palmitoyl Taurate, Sodium Methyl Stearoyl Taurate, Sodium Methyl 2-Sulfolaurate, Sodium Methyl 2-Sulfopalmitate, Sodium Methyl Taurate Isopalmitamide, Sodium Methyl Taurine Cocoyl Methyl Taurate, Sodium Myreth Sulfate, Sodium Myristate, Sodium Myristoamphoacetate, Sodium Myristoyl Glutamate, Sodium Myristoyl Hydrolyzed Collagen, Sodium Myristoyl Isethionate, Sodium Myristoyl Sarcosinate, Sodium Myristyl Sulfate, Sodium Nonoxynol-6 Phosphate, Sodium Nonoxynol-9 Phosphate, Sodium Nonoxynol-1 Sulfate, Sodium Nonoxynol-3 Sulfate, Sodium Nonoxynol-4 Sulfate, Sodium Nonoxynol-6 Sulfate, Sodium Nonoxynol-8 SulfateSodium nonoxynol-10 sulfate, sodium nonoxynol-25 sulfate, sodium octoxynol-2 ethanesulfonate, sodium octoxynol-2 sulfate, sodium octoxynol-6 sulfate, sodium octoxynol-9 sulfate, sodium oleate, sodium oleoamphoacetate, sodium oleoamphohydroxypropylsulfonate, sodium oleoamphopropionate, sodium oleoyl hydrolyzed collagen, sodium oleoyl isethionate, sodium oleth sulfate, sodium oleyl methyl isethionate, sodium oleyl sulfate, sodium oliveamphoacetate, sodium olive fatty acid, sodium olivoyl glutamate, sodium palmamphoacetate, sodium palm fatty acid, sodium palm glyceride sulfonate, sodium palmitate, sodium palmitoyl hydrolyzed collagen, sodium palmitoyl hydrolyzed wheat protein, sodium palmitoyl sarcosinate, sodium palm kernel acid, sodium palm carnelol isethionate, sodium palmoyl glutamate, Passiflora Edulis oil fatty acid sodium, peanut sodium amphoacetate, peanut sodium fatty acid sodium, PEG-6 cocamide carboxylate sodium, PEG-8 cocamide carboxylate sodium, PEG-4 cocamide sulfate sodium, PEG-3 lauramide carboxylate sodium, PEG-4 lauramide carboxylate sodium, palm fatty acid PEG-8 glycerides sodium carboxylate, pentaerythrityl hydroxypropyliminodiacetic acid dendrimer sodium, propoxylated PPG-2 acetate sodium, rapeseed oil fatty acid sodium, rice bran amphoacetate sodium, Sodium ricinoleate, sodium ricinoleoamphoacetate, sodium rosehip amphoacetate, sodium rosinate, sodium safflower oil fatty acid, sodium safflower oil hydrolyzed soy protein, sodium sesame seed oil fatty acid, sodium sesame amphoacetate, sodium shea butter amphoacetate, sodium soybean oil fatty acid, sodium soybean hydrolyzed collagen, sodium stearate, sodium stearoamphoacetate, sodium stearoamphohydroxypropylsulfonate, sodium stearoamphopropionate, sodium stearoyl caseinate,Sodium stearoyl glutamate, sodium stearoyl hyaluronate, sodium stearoyl hydrolyzed collagen, Sodium stearoyl hydrolyzed corn protein, sodium stearoyl hydrolyzed silk, sodium stearoyl hydrolyzed soy protein, sodium stearoyl hydrolyzed wheat protein, sodium stearoyl lactalbumin, sodium stearoyl methyl isethionate, sodium stearoyl oat protein, sodium stearoyl pea protein, sodium stearoyl soy protein, sodium stearyl dimethylglycinate, sodium stearyl sulfate, sunflower seed sodium amphoacetate, sodium surfactin, sweet almond sodium amphoacetate, sweet almond sodium fatty acid, sodium tallamphopropionate, sodium tallate, beef tallow sodium amphoacetate, beef tallow Sodium Fatty Acids, Sodium Tallow Sulfate, Sodium Tamanu Seed Oil Fatty Acids, Sodium Taurate, Sodium Taurine Methyl Cocoyl Taurate, Sodium Taurine Laurate, Sodium / TEA-Lauroyl Collagen Amino Acids, Sodium / TEA-Lauroyl Hydrolyzed Collagen, Sodium / TEA-Lauroyl Hydrolyzed Keratin, Sodium / TEA-Lauroyl Keratin Amino Acids, Sodium / TEA-Undecylenoyl Collagen Amino Acids, Sodium / TEA-Undecylenoyl Hydrolyzed Collagen, Sodium / TEA-Undecylenoyl Hydrolyzed Corn Protein, Sodium / TEA-Undecylenoyl Hydrolyzed Soy Protein, Sodium / TEA-Undecylenoyl Hydrolyzed Wheat Protein, Theobroma Grandiflorum seed acid sodium, trideceth-3 carboxylate, trideceth-4 carboxylate, trideceth-6 carboxylate, trideceth-7 carboxylate, trideceth-8 carboxylate, trideceth-12 carboxylate, trideceth-15 carboxylate, trideceth-19 carboxylate, trideceth sulfate, tridecylbenzenesulfonate, tridecyl sulfate, trimethylolpropane hydroxypropyliminodiacetic acid sodium dendrimer, undeceth-5 carboxylate, undecylenate, undecylenoamphoacetate, undecylenoamphopropionateSodium undecylenoyl glutamate, wheat germ sodium amphoacetate, sorbeth-160 tristearate, soy acid, soyamidopropylamine oxide, soyamidopropyl betaine, soybean oil glycereth-8 ester, stearamidopropylamine oxide, stearamidopropyl betaine, stearamine oxide, steareth-15, steareth-16, steareth-20, steareth-21, steareth-25, steareth-27, steareth-30, steareth-40, steareth-50, steareth-80, steareth-100, Steareth-2 Phosphate, Steareth-3 Phosphate, Stearic Acid, Stearoxypropyltrimonium Chloride, Stearoyl Glutamic Acid, Stearoyl Sarcosine, Stearyl Betaine, Stearyldimonium Hydroxypropyl Butylglucoside Chloride, Stearyldimonium Hydroxypropyl Decylglucoside Chloride, Stearyldimonium Hydroxypropyl Laurylglucoside Chloride, Sulfated Castor Oil, Sulfated Coconut Oil, Sulfated Glyceryl Oleate, Sulfated Olive Oil, Sulfated Peanut Oil, Sunflower Oil, MEA, Castor Oil Watercress seed acid, sunflower seed amidopropyl hydroxyethyldimonium chloride, sunflower seed oil glycereth-8 ester, tall oil acid, tallow acid, tallow amidopropylamine oxide, tallow amidopropyl betaine, tallow amidopropyl hydroxysultaine, tallow amine oxide, tallow betaine, tallow dihydroxyethyl betaine, tallow oil ethyl glucoside, TEA-abietoyl hydrolyzed collagen, TEA-C12-14 alkyl phosphate, TEA-C10-15 alkyl sulfate, TEA-C11-15 alkyl sulfate, TEVA TEA-C12~13 alkyl sulfate, TEA-C12~14 alkyl sulfate, TEA-C12~15 alkyl sulfate, TEA-C14~17 alkyl Sec sulfonate, TEA-carboxylate, TEA-cocamide diacetate, TEA-cocoate, TEA-coco-sulfate, TEA-cocoyl alaninate, TEA-cocoyl glutamate, TEA-cocoyl glutaminate, TEA-cocoyl glycinate, TEA-cocoyl hydrolyzed collagen, TEA-cocoyl hydrolyzed soy protein, TEA-cocoyl sarcosinate,TEA-Dimethicone PEG-7 Phosphate, TEA-Dodecylbenzenesulfonate, TEA-Hydrogenated Cocoate, TEA-Hydrogenated Beef Tallow Oil Glutamate, TEA-Isostearate, TEA-Isostearoyl Hydrolyzed Collagen, TEA-Lauraminopropionate, TEA-Laurate, TEA-Laurate / Myristate, TEA-Laureth Sulfate, TEA-Lauroyl Collagen Amino Acid, TEA-Lauroyl Glutamate, TEA-Lauroyl Hydrolyzed Collagen, TEA-Lauroyl Keratin Amino Acid, TEA-Lauroyl Methylaminopropionate, TEA-Lauroyl / Myristoyl Aspartate, TEA-Lauroyl Sarcosinate, T EA-Lauryl Phosphate, TEA-Lauryl Sulfate, TEA-Myristaminopropionate, TEA-Myristate, TEA-Myristoyl Hydrolyzed Collagen, TEA-Oleate, TEA-Oleoyl Hydrolyzed Collagen, TEA-Oleoyl Sarcosinate, TEA-Oleyl Sulfate, TEA-Palmitate, TEA-Palm Kernel Sarcosinate, TEA-PEG-3 Cocamide Sulfate, TEA-Rosinate, TEA-Stearate, TEA-Thorate, TEA-Tridecylbenzenesulfonate, TEA-Undecylenate, TEA-Undecylenoyl Hydrolyzed Collagen, Tetramethyldecynediol, Tetrasodium Dicarboxyethylstearyl Sulfosuccinamate, TIPA-Laureth Sulfate, TIPA-Lauryl Sulfate, TIPA-Myristate, TIPA-Stearate, Tocopheryl Phosphate, Trehalose Undecylenoate, TM-C12~15 Pareth-2 Phosphate, TM-C12~15 Pareth-6 Phosphate, TM-C12~15 Pareth-8 Phosphate, TM-C12~15 Pareth-10 Phosphate, Trideceth-20, Trideceth- 50, trideceth-3 carboxylic acid, trideceth-4 carboxylic acid, trideceth-7 carboxylic acid, trideceth-8 carboxylic acid, trideceth-15 carboxylic acid, trideceth-19 carboxylic acid, trideceth-10 phosphate, tridecylbenzenesulfonic acid, trilaureth-9 citric acid, trimethylolpropane hydroxypropyl bis-hydroxyethylamine dendrimer, lauroampho PG acetate chloride trisodium phosphate, undecanoic acid, undeceth-5 carboxylic acid, undecylenamidopropylamine oxide, undecylenamidopropyl betaine,Undecylenic Acid, Undecylenoyl Collagen Amino Acid, Undecylenoyl Glycine, Undecylenoyl Hydrolyzed Collagen, Undecylenoyl Wheat Amino Acid, Undecyl Glucoside, Wheat Germ Acid, Wheat Germ Amidopropylamine Oxide, Wheat Germ Amidopropyl Betaine, Yucca Schidigera Leaf / Root / Stem Extract, Yucca Schidigera Stem Extract, Zinc Coceth Sulfate and Zinc Cocos Sulfate.

[0315] Preservatives: For preservation purposes, the cosmetic or pharmaceutical composition according to the invention preferably comprises one or more preservatives suitable or customary for cosmetic or pharmaceutical compositions. Suitable and advantageous preservatives are, for example, phenoxyethanol, formaldehyde solution, parabens, pentanediol or sorbic acid.

[0316] Greens and synthetic polymers: The cosmetic or pharmaceutical composition according to the invention preferably comprises one or more polymers. Suitable cationic polymers are, for example, cationic cellulose derivatives, such as quaternized hydroxyethylcellulose available from Amerchol under the name Polymer JR400®, cationic starch, copolymers of diallylammonium salts and acrylamide, quaternized vinylpyrrolidone / vinylimidazole polymers, such as Luviquat® (BASF), condensation products of polyglycols and amines, such as quaternized collagen polypeptides, for example lauryldimonium hydroxypropyl hydrolyzed collagen (Lamequat® L, Grünau), quaternized wheat polypeptides, polyethyleneimine, cationic silicone polymers, such as amodimethicone, copolymers of adipic acid and dimethylaminohydroxypropyldiethylenetriamine (Cartaretine®, Sandoz), copolymers of acrylic acid and dimethyldiallylammonium chloride (Cartaretine®, Sandoz), copolymers of chitin (Merquat® 550, Chemviron), polyaminopolyamides and their crosslinked water-soluble polymers, for example cationic chitin derivatives such as quaternized chitosan, condensation products of dihaloalkyls, for example dibromobutane, with bisdialkylamines, for example bis-dimethylamino-1,3-propane, optionally in microcrystalline distribution, cationic guar gums, such as Jaguar® CBS, Jaguar® C-17, Jaguar® C-16 from Celanese, quaternized ammonium salt polymers, such as Mirapol® A-15, Mirapol® AD-1, Mirapol® AZ-1 from Miranol, and the various polyquaternium types (for example 6, 7, 32 or 37) that can be found on the market under the trade names Rheocare® CC or Ultragel® 300.Suitable anionic, zwitterionic, amphoteric and nonionic polymers are, for example, vinyl acetate / crotonic acid copolymers, vinylpyrrolidone / vinyl acrylate copolymers, vinyl acetate / butyl maleate / isobornyl acrylate copolymers, methyl vinyl ether / maleic anhydride copolymers and esters thereof, uncrosslinked and polyol-crosslinked polyacrylic acids, acrylamidopropyltrimethylammonium chloride / acrylate copolymers, octylacrylamide / methyl methacrylate / tert-butylaminoethyl methacrylate / 2-hydroxypropyl methacrylate copolymers, polyvinylpyrrolidone, vinylpyrrolidone / vinyl acetate copolymers, vinylpyrrolidone / dimethylaminoethyl methacrylate / vinyl caprolactam terpolymers, and optionally derivatized cellulose ethers and silicones. In a preferred variant, the cosmetic or pharmaceutical composition according to the invention preferably comprises uncrosslinked or polyol-crosslinked polyacrylic acid as the polymer component.

[0317] Thickeners and / or rheological additives: The cosmetic or pharmaceutical composition according to the invention preferably comprises one or more thickeners and / or rheological additives. Suitable thickeners are polymeric thickeners such as Aerosil® type (hydrophilic silicas), polysaccharides, more particularly xanthan gum, guar guar, agar, alginates and tylose, carboxymethylcellulose and hydroxyethylcellulose, as well as relatively high molecular weight polyethylene glycol monoesters and diesters of fatty acids, polyacrylates (e.g. Carbopols® [Goodrich] or Synthalens® [Sigma]), polyacrylamides, polyvinyl alcohols and polyvinylpyrrolidones, surfactants such as ethoxylated fatty acid glycerides, esters of fatty acids and polyols, such as pentaerythritol or trimethylolpropane, narrow-range fatty alcohol ethoxylates, and electrolytes such as sodium chloride and ammonium chloride.

[0318] Perfume oils and / or fragrances: The cosmetic or pharmaceutical compositions according to the invention preferably comprise one or more perfume oils and / or fragrances. Suitable perfume oils are mixtures of natural and synthetic fragrances. Natural fragrances include flower extracts (lily, lavender, rose, jasmine, neroli, ylang-ylang), stems and leaves (geranium, patchouli, petitgrain), fruits (anise, coriander, caraway, juniper), peels (bergamot, lemon, orange), roots (nutmeg, angelica, celery, cardamom, costus, iris, calamus), woods (pine, sandalwood, guaiacwood, cedarwood, rosewood), herbs and grasses (tarragon, lemongrass, sage, thyme), needles and branches (spruce, fir, pine, pumice), resins and balsams (galbanum, elemi, benzoin, myrrh, olibanum, opoponax). Animal-derived materials, such as civet and beaver, can also be used. Representative synthetic fragrance compounds are products of the ester, ether, aldehyde, ketone, alcohol, and hydrocarbon types. Examples of ester-type fragrance compounds are benzyl acetate, phenoxyethyl isobutyrate, p-tert-butylcyclohexyl acetate, linalyl acetate, dimethylbenzyl carbinyl acetate, phenylethyl acetate, linalyl benzoate, benzyl formate, ethylmethylphenylglycinate, allyl cyclohexylpropionate, styrallyl propionate, and benzyl salicylate. Ethers include, for example, benzyl ethyl ether, while aldehydes include, for example, linear alkanals containing 8 to 18 carbon atoms, such as citral, citronellal, citronellyloxyacetaldehyde, cyclamen aldehyde, hydroxycitronellal, lilial, and bourgeonal. Examples of suitable ketones are the ionones, beta-isomethylionone, and methyl cedryl ketone. Suitable alcohols are anethole, citronellol, eugenol, isoeugenol, geraniol, linalool, phenylethyl alcohol, and terpineol. Hydrocarbons include primarily terpenes and balsams. However, it is preferable to use mixtures of various fragrance compounds that together produce a pleasant scent.Other suitable perfume oils are essential oils of relatively low volatility that are primarily used as aroma components, examples being sage oil, chamomile oil, clove oil, melissa oil, mint oil, cinnamon leaf oil, lime blossom oil, juniper berry oil, vetiver oil, olibanum oil, galbanum oil, ladanum oil and lavandin oil. The following are preferably used individually or in mixtures: bergamot oil, dihydromyrcenol, lilial, lyral, citronellol, phenylethyl alcohol, hexyl cinnamaldehyde, geraniol, benzyl acetone, cyclamen aldehyde, linalool, boisambrene forte, ambroxan, indole, hedione, sandelice, citrus oil, mandarin oil, orange oil, allyl amyl glycolate, cyclovertal, lavandin oil, salvia oil, damascone, geranium oil bourbon, cyclohexyl salicylate, vertifex coeur, Iso-E-Super, Fixolide NP, evernyl, iraldein gamma, phenylacetic acid, geranyl acetate, benzyl acetate, rose oxide, romilate, irotyl and floramate.

[0319] Anti-cellulite agents: The cosmetic or pharmaceutical compositions according to the present invention preferably contain one or more anti-cellulite agents. The anti-cellulite agents and lipolytic agents are preferably selected from the group consisting of beta-adrenergic receptor agonists, such as synephrine and its derivatives, and cyclohexylcarbamates. Agents that enhance or increase the activity of the anti-cellulite agents, in particular agents that stimulate and / or depolarize C nerve fibers, are preferably selected from the group consisting of capsaicin and its derivatives, vanillyl-nonylamide and its derivatives, L-carnitine, coenzyme A, isoflavonoids, soybean extract, ananas extract, and conjugated linoleic acid.

[0320] Fat-enhancing agents: The cosmetic or pharmaceutical compositions according to the present invention preferably comprise one or more fat-enhancing agents and / or adipogenic agents, as well as an agent that enhances or increases the activity of the fat-enhancing agent. An example of a fat-enhancing agent is hydroxymethoxyphenylpropylmethylmethoxybenzofuran (trade name: Sym3D®).

[0321] Superfatting agents and / or consistency factors: The cosmetic or pharmaceutical compositions according to the present invention preferably contain one or more superfatting agents and / or consistency factors. Superfatting agents can be selected from substances such as lanolin and lecithin, as well as polyethoxylated or acylated lanolin and lecithin derivatives, polyol fatty acid esters, monoglycerides, and fatty acid alkanolamides, which also function as foam stabilizers. The most commonly used consistency factors are fatty alcohols or hydroxy fatty alcohols containing 12 to 22, preferably 16 to 18, carbon atoms, as well as partial glycerides, fatty acids, or hydroxy fatty acids. Combinations of these substances with alkyl oligoglucosides and / or fatty acid N-methylglucamides and / or polyglycerol poly-12-hydroxystearates of the same chain length are preferably used.

[0322] Pearlescent Waxes: The cosmetic or pharmaceutical composition according to the invention preferably comprises one or more pearlescent waxes. Suitable pearlescent waxes are, for example, alkylene glycol esters, in particular ethylene glycol distearate, fatty acid alkanolamides, in particular coco fatty acid diethanolamide, partial glycerides, in particular stearic acid monoglyceride, esters of optionally hydroxy-substituted polycarboxylic acids with fatty alcohols containing 6 to 22 carbon atoms, in particular long-chain esters of tartaric acid, fatty compounds such as fatty alcohols, fatty ketones, fatty aldehydes, fatty ethers and fatty carbonates, all containing at least 24 carbon atoms, in particular laurone and distearyl ether, fatty acids such as stearic acid, hydroxystearic acid or behenic acid, ring-opening products of olefin epoxides containing 12 to 22 carbon atoms with fatty alcohols containing 12 to 22 carbon atoms and / or polyols containing 2 to 15 carbon atoms and 2 to 10 hydroxyl groups, and mixtures thereof.

[0323] Silicones: In order to impart a silky, smooth and luxurious texture, to make the skin look and feel smoother, and to improve processability (anti-foaming), the cosmetic or pharmaceutical composition according to the invention preferably comprises one or more silicones or silicone derivatives. Suitable silicones are acefylline methylsilanol mannuronate, acetylmethionylmethylsilanol elastinate acrylates / behenyl, acrylates / dimethicone methacrylate copoly...

Claims

1. (a) a mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols different from the first linear alkanediol having a carbon chain of 5 to 14 carbon atoms; (b) at least one lipophilic active component having a log P O / W value of ≧0 to 25.00; and (c) optionally a cosmetic or pharmaceutical composition or a home care product comprising or consisting of at least one active substance and / or additive for the cosmetic or pharmaceutical composition or home care product different from the lipophilic active component (b), wherein the mixture comprising at least one first linear alkanediol and one or more second linear alkanediols is a mixture comprising 1,2-pentanediol and 2,3-pentanediol; a mixture comprising 1,2-hexanediol and 2,3-hexanediol; a mixture comprising 1,2-heptanediol and 2,3-heptanediol; a mixture comprising 1,2-octanediol and 2,3-octanediol; a mixture comprising 1,2-nonanediol and 2,3-nonanediol; A cosmetic or pharmaceutical composition or home care product selected from the group consisting of:

2. 2. The cosmetic or pharmaceutical composition or home care product according to claim 1, wherein the mixture comprising at least one first linear alkanediol and one or more second linear alkanediols comprises the first linear alkanediol and the second alkanediol in a ratio ranging from 50:50 to 99.9:0.

1.

3. A cosmetic or pharmaceutical composition or home care product according to claim 1 or 2, At least one lipophilic active component is selected from the group consisting of tocopherol, bisabolol, ethylhexylglycerin, o-cymen-5-ol, propanediol caprylate, glyceryl caprylate, retinol palmitate, retinol, farnesol, glyceryl laurate, polyglyceryl-2 caprylate, hydroxyacetophenone, caffeine, undecylenoyl phenylalanine, phenylethyl resorcinol, hydroxymethoxyphenyldecanone, Zingiber Officinale (Ginger) Root Extract, myristoyl nonapeptide-3, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, palmitoyl pentapeptide-4, hydroxypinacolone retinoic acid, Isochrysis galbana (Isochrysis galbana) root extract, hydroxypinacolone retinoic acid, hydroxyisothiazolinone ...

1. A cosmetic or pharmaceutical composition or home care product, comprising a lipophilic cosmetic active ingredient selected from the group consisting of Galbana extract, sclareolide, vanillyl butyl ether, hydroxyphenylpropamidobenzoic acid, 4-t-butylcyclohexanol, ubiquinone-10, climbazole and mixtures of two or more of the aforementioned active ingredients, and / or wherein at least one lipophilic active ingredient is a lipophilic pharmaceutically active ingredient selected from the group consisting of erythromycin, betamethasone, ibuprofen, ketoprofen, diclofenac, metronidazole, imiquimod, celecoxib, indomethacin, caffeine, minoxidil, hydrocortisone and mixtures of two or more of the aforementioned lipophilic pharmaceutically active ingredients.

4. at least one solubilizing agent, such as PEG-40 hydrogenated castor oil, polysorbate-20, 60 and 80, PEG-8, PEG-7 glyceryl cocoate, decyl glucoside, ceteareth-20, cetearyl glucoside, PEG-60 hydrogenated castor oil, steareth-2, steareth-20, PPG-26-buteth-26, PPG-5-laureth-5, steareth-21, trideceth-9, PEG-32, glycereth- 26, polyglyceryl-3 distearate, methyl gluceth-20, PEG-12 laurate, polyglyceryl-4 caprylate, oleth-20, oleth-2, polyglyceryl-4 caprate, PPG-1-PEG-9 lauryl glycol ether, polyglyceryl-2 caprate, isocedeth-20, PPG-13-decyltetradeceth-24 or a mixture of two or more of the aforementioned solubilizers.

4. The cosmetic or pharmaceutical composition or home care product according to claim 1, further comprising a solubilizer and / or at least one hydrophilic solvent different from the compounds contained in mixture (a), selected from the group consisting of glycerin, propylene glycol, butylene glycol, isopropyl alcohol, propanediol, dipropylene glycol, propylene carbonate, ethanol, hexylene glycol, glycerin carbonate, methylpropanediol, butylene carbonate, dimethyl isosorbide, 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, or a mixture of two or more of the aforementioned hydrophilic solvents.

5. At least one active substance and / or additive for a cosmetic or pharmaceutical composition or home care product other than the lipophilic active component (b) is selected from the group consisting of agents against skin aging, antimicrobial agents, antioxidants, chelating agents, emulsifiers, surfactants, green and synthetic polymers, skin cooling agents, rheological additives, oils, fragrances or perfume oils, and mixtures of two or more of the aforementioned substances, and the antimicrobial agent is selected from the group consisting of 4-hydroxybenzoic acid and its salts and esters, N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea, 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), 4-chloro-3,5-dimethyl-phenol, 2,2'-methylenebis(6-bromo-4-chlorophenol), 3-methyl-4- 5. The cosmetic or pharmaceutical composition or home care product according to any one of claims 1 to 4, wherein the active ingredient is selected from the group consisting of (1-methylethyl)phenol, 2-benzyl-4-chlorophenol, 3-(4-chlorophenoxy)-1,2-propanediol, 3-iodo-2-propynyl butylcarbamate, chlorhexidine, 3,4,4'-trichlorocarbanilide (TTC), antibacterial fragrance, thymol, thyme oil, eugenol, clove oil, menthol, mint oil, farnesol, phenoxyethanol, glycerol monocaprate, glycerol monocaprylate, glycerol monolaurate (GML), diglycerol monocaprate (DMC), salicylic acid N-alkylamide, n-octyl salicylamide, or n-decyl salicylamide.

6. a mixture comprising at least one first linear alkanediol and one or more second linear alkanediols in an amount of 0.001 to 15.0 wt. %, based on the total weight of the composition or home care product; and / or and / or comprising a 2,3-alkanediol of a mixture comprising at least one first linear alkanediol and one or more second linear alkanediols in an amount of 0.001 to 15.0 wt. %, based on the total weight of the composition or home care product. A cosmetic or pharmaceutical composition or home care product according to any one of claims 1 to 5, comprising at least one lipophilic active component in an amount of 0.001 to 5.0% by weight, based on the total weight of the composition.

7. - in the form of a dispersion, an emulsion selected from the group consisting of an O / W emulsion, a W / O emulsion, a multiple emulsion, a water-dispersed gel, a balm, a water-in-oil (W / O / W) or oil-in-water (O / W / O) multiple emulsion, a PIT emulsion, a Pickering emulsion, a microemulsion, a liquid, a lotion, a suspension, a milk, an ointment, a paste, a gel, a cream-based, an oil-based or a liposome-based formulation, comprising an oil component in an amount of ≥ 1% by weight, or - in the form of a liquid surfactant formulation, or - in the form of a solid surfactant formulation, or in aqueous or aqueous / alcoholic form, containing alcohol or glycol in an amount of 0.1% to ≦50% by weight, based on the total weight of the solution; A cosmetic or pharmaceutical composition or home care product according to any one of claims 1 to 6, wherein the cosmetic or pharmaceutical composition is a cold-blended preparation.

8. 8. Cosmetic non-therapeutic use of a cosmetic composition according to any one of claims 1 to 7 for personal care in skin protection, skin care, scalp protection, scalp care, hair care, nail care, for treating skin conditions, skin ageing, wrinkle formation, loss of skin volume, loss of skin elasticity, pigmentation spots, dryness, peeling, oiliness, skin moisturising or for animal care.

9. 9. The pharmaceutical composition according to any one of claims 1 to 8, for use as a medicament for the prevention and / or treatment of intolerant or sensitive skin, skin irritation, skin redness, wheals, pigmentation disorders, skin hypo- and / or hyperpigmentation, dysfunction of human hair, skin and / or nails, dermatological or keratological diseases, wherein the dermatological or keratological disease is selected from the group consisting of atopic dermatitis (neurodermatitis), psoriasis, acneiform rash, asteatosis, xeroderma, eczema, hyper- and hyposeborrhea, dermatitis, rosacea, erythema, wheals, pruritus (itching), inflammation, irritation, fibrosis, lichen planus, pityriasis rosea, tinea versicolor, autoimmune bullous diseases, urticaria, angioedema, allergic skin reactions, wound healing, tissue regeneration, and for the treatment of inflammation or pain.

10. - to increase the solubility of lipophilic active ingredients in cosmetic or pharmaceutical compositions or home care products compared to cosmetic or pharmaceutical compositions or home care products containing lipophilic active ingredients without the use of alkanediols, and / or - to increase the concentration of lipophilic active ingredients in cosmetic or pharmaceutical compositions or home care products compared to cosmetic or pharmaceutical compositions or home care products containing lipophilic active ingredients without the use of alkanediols, and / or - use of a mixture comprising at least one first linear alkanediol and one or more second linear alkanediols to reduce or prevent foam formation in a cosmetic or pharmaceutical composition or home care product comprising a solubilizer compared to foam formation in a cosmetic or pharmaceutical composition or home care product comprising a solubilizer without an alkanediol, wherein the mixture comprises at least one first linear alkanediol and one or more second linear alkanediols a mixture comprising 1,2-pentanediol and 2,3-pentanediol; a mixture comprising 1,2-hexanediol and 2,3-hexanediol; a mixture comprising 1,2-heptanediol and 2,3-heptanediol; a mixture comprising 1,2-octanediol and 2,3-octanediol; a mixture comprising 1,2-nonanediol and 2,3-nonanediol; The use of any one of the following:

11. 1. Use of a mixture comprising at least one first linear alkanediol and one or more second linear alkanediols as a solubilizer supplement in a cosmetic or pharmaceutical composition or a home care product, wherein the mixture comprising at least one first linear alkanediol and one or more second linear alkanediols comprises: a mixture comprising 1,2-pentanediol and 2,3-pentanediol; a mixture comprising 1,2-hexanediol and 2,3-hexanediol; a mixture comprising 1,2-heptanediol and 2,3-heptanediol; a mixture comprising 1,2-octanediol and 2,3-octanediol; a mixture comprising 1,2-nonanediol and 2,3-nonanediol; The use of any one of the following:

Citation Information

Patent Citations

  • Sedative

    JP2012171961A

  • Cosmetic Blend

    JP2020502082A

  • Compounds for skin improvement / treatment

    WO2018154145A2