Composition
Patent Information
- Application Number
- PCT/JP2024/027291
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-08-01
- Filing Date
- 2024-07-31
- Publication Date
- 2025-02-06
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Figure JPOXMLDOC01-APPB-T000001 
Figure JPOXMLDOC01-APPB-T000002 
Figure JPOXMLDOC01-APPB-T000003
Abstract
Description
composition
[0001] The present technology relates to a composition containing stearyl glycyrrhetinate and niacinamide or tranexamic acid, and also to an odor improving agent and method for improving the odor of stearyl glycyrrhetinate.
[0002]
[0003] Stearyl glycyrrhetinate, an oil-soluble drug, is a derivative of glycyrrhetinic acid, which is the aglycone of glycyrrhizic acid found in large quantities in plants such as Glycyrrhiza Glabra of the Leguminosae family. Stearyl glycyrrhetinate has anti-inflammatory and anti-allergic effects, and is known to be highly safe for the human body. For this reason, stearyl glycyrrhetinate is used in a wide variety of cosmetics and topical skin preparations. For example, a topical cream containing a cream base, fucoidan, stearyl glycyrrhetinate, and water, and containing 0.2% by weight or more of the fucoidan in terms of fucose, is disclosed (see Patent Document 1).
[0003] Niacinamide, also known as nicotinamide, is a water-soluble vitamin (vitamin B3). Niacinamide is generally known to have anti-wrinkle and antioxidant properties. For this reason, niacinamide is used in a wide variety of cosmetics and topical skin preparations. For example, Patent Document 2 discloses a technology for an oil-in-water emulsion cosmetic that contains a specific amount of an ultraviolet absorber that is solid at 25°C, a polar oil that is liquid at 25°C, polyoxyethylene hydrogenated castor oil and / or polyoxyethylene sorbitan fatty acid ester, a specific amount of nicotinamide, and a partially crosslinked organopolysiloxane polymer.
[0004] Tranexamic acid is a type of amino acid artificially synthesized from lysine, an essential amino acid that is a component of proteins. Tranexamic acid is generally known to have anti-inflammatory and whitening effects. For this reason, tranexamic acid is used in a wide variety of cosmetics and topical skin preparations. For example, Patent Document 3 discloses a technology for an oil-in-water emulsion-type cosmetic or topical skin preparation that contains tranexamic acid, lysophospholipids, phospholipids, and a specific oil that is liquid at 25°C and has excellent sensory properties and stability over time.
[0005] JP 2016-88859 A JP 2018-172379 A JP 2016-88874 A
[0006] Conventionally, oil-soluble compounds such as oils have a unique oily odor, and there is a concern that the odor may change over time. On the other hand, stearyl glycyrrhetinate, an oil-soluble drug, is known as a component that has almost no odor, and the concern that the odor may change over time has not been considered. Therefore, the present inventor has focused on the concern that stearyl glycyrrhetinate may change its odor over time, and as a result of intensive research, has newly discovered that stearyl glycyrrhetinate may change its odor over time, generating an unpleasant odor (unpleasant odor). However, regarding the odor change of stearyl glycyrrhetinate, there has been insufficient knowledge about what components are suitable for improving the odor change.
[0007] The main object of the present invention is to provide a technology capable of improving the offensive odor of stearyl glycyrrhetinate, particularly, to provide a technology capable of improving the offensive odor of stearyl glycyrrhetinate promoted by niacinamide or tranexamic acid.
[0008] The present inventors have conducted research focusing on concerns about the offensive odor of stearyl glycyrrhetinate. As a result, they have found that the incorporation of niacinamide or tranexamic acid exacerbates the offensive odor of stearyl glycyrrhetinate over time compared to when niacinamide or tranexamic acid is not incorporated, resulting in the generation of an unpleasant odor (unpleasant odor). This represents a new and unknown problem for stearyl glycyrrhetinate, which has traditionally been considered to have almost no odor and little odor concern. Therefore, the present inventors have conducted extensive trial and error to find components that can improve the offensive odor of stearyl glycyrrhetinate exacerbated by the incorporation of niacinamide or tranexamic acid. As a result, they have found that certain fragrance components have excellent masking effects on the offensive odor of stearyl glycyrrhetinate and excellent matching effects with the offensive odor of stearyl glycyrrhetinate, thereby completing the present invention.
[0009] That is, the present invention provides the following [1] to
[17] . [1] A method for improving the odor of a composition containing stearyl glycyrrhetinate and niacinamide or tranexamic acid, comprising adding an anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), or methylparaben (MPA) to the composition. Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate, Muscenone, Benzyl Acetate, Phenylethyl Alcohol alcohol), phenylethyl acetate,[2] A method for improving the odor of a composition containing stearyl glycyrrhetinate and tranexamic acid, comprising adding to the composition anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexanol, linalool, cedryl acetate, Iso E Super (Iso E Super), or methylparaben. Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate, Muscenone, Benzyl Acetate, Phenylethyl Alcohol alcohol), phenylethyl acetate,[3] A method for improving the odor of a composition containing stearyl glycyrrhetinate and niacinamide, comprising adding to the composition anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexanol, linalool, cedryl acetate, Iso E Super (Iso E Super), or niacinamide. Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Geraniol, Geranyl acetate Acetate), Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate, Muscenone, Benzyl Acetate,The method for improving an offensive odor comprises adding at least one selected from the group consisting of phenylethyl alcohol, phenylethyl acetate, heliotropine, damascone, benzyl alcohol, and methyl 2-octynoate. [4] An odor improving agent for improving the odor of a composition containing stearyl glycyrrhetinate and niacinamide or tranexamic acid, the odor improving agent comprising anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate), damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol,The odor improving agent contains at least one active ingredient selected from the group consisting of bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, and heliotropine. [5] An odor improving agent for improving the odor of a composition containing stearyl glycyrrhetinate and tranexamic acid, the odor improving agent comprising anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate), damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol,The odor improving agent contains at least one active ingredient selected from the group consisting of bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, and heliotropine. [6] An odor improving agent for improving the odor of a composition containing stearyl glycyrrhetinate and niacinamide, the odor improving agent comprising anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), and / or niacinamide. Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Geraniol, Geranyl acetate Acetate), Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal,The offensive odor improving agent contains, as an active ingredient, at least one selected from the group consisting of nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, heliotropine, damascone, benzyl alcohol, and methyl 2-octynoate. [7] The following ingredients (A) to (C): (A) stearyl glycyrrhetinate, (B) niacinamide or tranexamic acid, (C) anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate), damascenone, anisaldehyde, benzaldehyde,At least one selected from the group consisting of Magnolan, Mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, and heliotropine. [8] A composition for improving odors of stearyl glycyrrhetinate and niacinamide or tranexamic acid, comprising the following components (A) to (C): (A) stearyl glycyrrhetinate, (B) tranexamic acid, (C) anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate), damascenone, anisaldehyde,At least one selected from the group consisting of benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, and heliotropine. [9] A composition for improving odors of stearyl glycyrrhetinate and tranexamic acid, comprising the following components (A) to (C): (A) stearyl glycyrrhetinate, (B) niacinamide, (C) anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Geraniol, Geranyl acetate acetate),Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate, Muscenone, Benzyl Acetate, Phenylethyl Alcohol The present invention relates to a composition for improving an offensive odor, which comprises stearyl glycyrrhetinate and niacinamide, and which contains at least one member selected from the group consisting of phenylalanine, phenylethyl acetate, heliotropin, damascone, benzyl alcohol, and methyl 2-octynoate.
[10] The following ingredients (A) to (C): (A) stearyl glycyrrhetinate, (B) niacinamide or tranexamic acid, and (C) anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol,Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethyl Benzyl Carbinol The composition contains at least one selected from the group consisting of benzophenone, benzoyl benzoate, ...
[11] The following ingredients (A) to (C): (A) stearyl glycyrrhetinate, (B) tranexamic acid, (C) anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol,Ethyl vanillin, maltol, linalyl acetate, α-terpineol, benzyl benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol The composition contains at least one selected from the group consisting of benzophenone, benzoyl benzoate, ...
[12] The following ingredients (A) to (C): (A) stearyl glycyrrhetinate, (B) niacinamide, (C) anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol,Ethyl vanillin, maltol, linalyl acetate, α-terpineol, geraniol, geranyl acetate, benzyl benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethylbenzyl carbinol The composition contains at least one selected from the group consisting of benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, heliotropine, damascone, benzyl alcohol, and methyl 2-octynoate.
[13] The composition according to any one of
[10] to
[12] , wherein the mass ratio (A) / (C) of the component (A) to the component (C) is 5 to 2000.
[14] The composition according to
[11] , wherein the mass ratio (A) / (B) of the component (A) to the component (B) is 1 or less.
[15] The composition according to
[12] , wherein the mass ratio (A) / (B) of the component (A) to the component (B) is 10 or less.
[16] A cosmetic or topical skin preparation comprising the composition according to any one of
[10] to
[12] .
[17] The cosmetic or topical skin preparation according to
[16] , wherein the cosmetic or topical skin preparation contains at least an oily agent, and the content of the oily agent is 2 to 20 mass%.
[0010] The composition of the present invention can improve the bad odor caused by stearyl glycyrrhetinate while exhibiting various skin effects of stearyl glycyrrhetinate and niacinamide or tranexamic acid.The effect of improving the bad odor caused by stearyl glycyrrhetinate includes, for example, a masking effect, a matching effect, a lasting effect, etc., and the present invention is excellent in these effects.The effects described here are not necessarily limited, and may be any of the effects described in this specification.
[0011] Preferred embodiments for carrying out the present invention will be described below. Note that the embodiment described below shows one example of a typical embodiment of the present invention, and the scope of the present invention should not be construed narrowly by this. Furthermore, percentages in this specification are expressed by mass unless otherwise specified. Furthermore, the upper limit (or less) and the lower limit (or more) of each numerical range (to) can be arbitrarily combined as desired. In this specification, the range "X to Y" includes X and Y and means "X or more and Y or less."
[0012] In the present invention, the "off-odor" of stearyl glycyrrhetinate refers to a sensory unpleasant odor (hereinafter sometimes abbreviated as "unpleasant odor") that develops over time and is derived from stearyl glycyrrhetinate, and is particularly an unpleasant odor that is enhanced by combined use with niacinamide or tranexamic acid. In the present invention, the unpleasant odor of stearyl glycyrrhetinate is not particularly limited, but is usually an oily odor. Furthermore, from the viewpoint of being able to more effectively experience the masking effect, matching effect, and lasting effect of the present invention, it is more preferable to target off-odor under high-temperature conditions (e.g., 50°C) where there is a high risk of off-odor.
[0013] In the present invention, the "masking effect" refers to the effect of relatively improving an unpleasant odor by making a strong, pleasant fragrance (aroma, fragrance) compete with the unpleasant odor.
[0014] In the present invention, the "matching effect" refers to the effect of improving an unpleasant odor by mixing a scent (aroma, fragrance) that harmonizes with the unpleasant odor, incorporating the unpleasant odor as a component of a pleasant scent, and harmonizing the unpleasant odor as a whole into a pleasant scent.
[0015] In the present invention, the term "lasting effect" refers to the effect of improving unpleasant odors by maintaining a pleasant fragrance for a long time.
[0016] In the present invention, "improving strange odors (unpleasant odors)" means preventing the unpleasant odor from being perceived by the senses (eliminating the unpleasant odor) or alleviating the unpleasant odor. Furthermore, in the present invention, "deodorization" is synonymous with "improving strange odors (unpleasant odors)" unless otherwise specified.
[0017] The composition according to the first embodiment of the present invention will be described. The composition according to the first embodiment contains component (A) stearyl glycyrrhetinate, component (B) niacinamide, and component (C) a fragrance component.
[0018] <Component (A)> Stearyl glycyrrhetinate, component (A) used in the present invention, is a compound obtained by esterifying stearic acid to the hydroxyl group of glycyrrhetinic acid obtained by hydrolysis of glycyrrhetinic acid contained in licorice and the like. The systematic name is octadecyl (20S)-3β-hydroxy-11-oxo-5α-olean-12-en-29-oate. The molecular formula is C 48 H 82 O 4 and its molecular weight is 723.16. The molecular structure of glycyrrhetinic acid is planar, and since the 3- and 11-positions are similar to cortisone, it has anti-inflammatory, anti-allergic, and whitening effects. Since the safety of stearyl glycyrrhetinate is enhanced by the addition of stearic acid, it is widely used in technical fields such as cosmetics and topical skin preparations, which require safety.
[0019] The stearyl glycyrrhetinate used in the present invention is contained as a component that imparts anti-inflammatory, anti-allergic, whitening effects, etc., and there are no particular restrictions on the manufacturing method or purity as long as it is one that is used in ordinary cosmetics, topical skin preparations, etc., but it is preferable that it conforms to the "stearyl glycyrrhetinate" listed in the standards for quasi-drug ingredients, for example.
[0020] The content of component (A) in the present invention is not particularly limited, but is preferably 0.01% by mass (hereinafter simply referred to as %) or more, more preferably 0.05% or more, and even more preferably 0.1% or more, based on the total amount of the composition. Also, it is preferably 10% or less, more preferably 5% or less, and even more preferably 2% or less. By setting it in this range, various skin effects of stearyl glycyrrhetinate are excellent, and the masking effect and matching effect are more excellent, so it is more preferable.
[0021] The content of component (A) in the present invention is not particularly limited, but is preferably 0.01 to 10%, more preferably 0.05 to 5%, and even more preferably 0.1 to 2%, based on the total amount of the composition. This range is more preferable because it provides excellent skin effects of stearyl glycyrrhetinate, as well as excellent masking and matching effects.
[0022] <Component (B)> The component (B) niacinamide used in the present invention is an amide compound of nicotinic acid (vitamin B3 / niacin). Niacinamide is a water-soluble vitamin and a known substance that is a member of the B vitamin family. It can be extracted from natural products (such as rice bran) or synthesized by known methods. Specifically, those listed in the 17th edition of the Japanese Pharmacopoeia can be used.
[0023] The content of component (B) in the present invention is not particularly limited, but is preferably 0.005 to 10%, more preferably 0.01 to 10%, even more preferably 0.1 to 10%, even more preferably 1 to 8%, and particularly preferably 2 to 6%, based on the total amount of the composition. This range is more preferable because it ensures good masking and matching effects while providing excellent skin benefits of niacinamide.
[0024] In the present invention, the content mass ratio (A) / (B) of component (A) to component (B) is not particularly limited, but is preferably 10 or less, more preferably 5 or less, even more preferably 1 or less, even more preferably 0.5 or less, particularly preferably 0.3 or less, and more preferably 0.1 or less. In addition, the content mass ratio (A) / (B) is preferably 0.001 or more, more preferably 0.005 or more, and even more preferably 0.01 or more. By setting it within this range, various skin effects of niacinamide are excellent while ensuring good masking effect and matching effect, so it is more preferable.
[0025] In the present invention, the mass ratio (A) / (B) of component (A) to component (B) is preferably 0.001 to 10, more preferably 0.005 to 5, even more preferably 0.005 to 1, even more preferably 0.01 to 0.5, particularly preferably 0.01 to 0.3, and more preferably 0.01 to 0.1. By setting it within this range, various skin effects of niacinamide are excellent while ensuring good masking effect and matching effect, and this is more preferable.
[0026] <Component (C)> Component (C) used in the present invention is a fragrance component for improving the offensive odor of component (A), stearyl glycyrrhetinate. Component (C) includes anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super, sandalore, ambroxan, γ-terpinene, ambrettolide, β-ionone, borneol, and isobutylquinoline. Quinoline), Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl AcetateAcetate), α-Terpineol, Geraniol, Geranyl Acetate, Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate The component (C) is at least one selected from the group consisting of methyl methacrylate, ...
[0027]
[0028] Component (C) is a hydrocarbon such as α-pinene or γ-terpinene; an alcohol such as linalool, geraniol, citronellol, α-terpineol, farnesol, borneol, patchouli alcohol, cedrol, anise alcohol, 1-hexanol, eugenol, guaiacol, sandalore, mayol, nerol, dimethylbenzylcarbinol, bacdanol, phenylethyl alcohol, or benzyl alcohol; or an ether such as ambroxan, magnol, or phenylacetaldehyde dimethyl acetal. These fragrance components are classified into aldehydes such as citral, ethyl vanillin, anisaldehyde, benzaldehyde, and heliotropin; ketones such as β-ionone, maltol, Iso-E-Super, damascenone, and damascone; esters such as cedryl acetate, geranyl acetate, linalyl acetate, benzyl benzoate, methyl anthranilate, benzyl acetate, phenylethyl acetate, and methyl 2-octynoate; synthetic musks such as ambretride and muscenone; and nitrogen-containing compounds such as isobutylquinoline.
[0029] In the present invention, from the viewpoint of excellent masking effect against the offensive odor of component (A), component (C) is preferably at least one selected from the group consisting of components (1) to (4), (6) to (20), (23) to (33), (35) to (41), (44), and (45) in Table 1, and more preferably at least one selected from the group consisting of components (2), (8), (10), (11), (18), (27), (29), (33), (38), (39), and (45) in Table 1.
[0030] In the present invention, from the viewpoint of achieving an excellent matching effect against the odor of component (A), component (C) is preferably at least one selected from the group consisting of components (1) to (45) in Table 1, and more preferably at least one selected from the group consisting of components (1), (9), (10), (15), (18), (20), (25), (27), (30), (36), (38), and (45) in Table 1.
[0031] In the present invention, from the viewpoint of achieving a superior masking effect and matching effect against the odor of component (A), it is more preferable that component (C) be at least one selected from the group consisting of components (10), (18), (27), (38), and (45) in Table 1.
[0032] The content of component (C) in the present invention is not particularly limited, but is preferably 0.0001% or more, more preferably 0.0005% or more, and even more preferably 0.001% or more, based on the total amount of composition.Moreover, it is preferably 1% or less, more preferably 0.5% or less, and even more preferably 0.2% or less.By making it in this range, it is more preferable because it has better masking effect and matching effect against the odor of component (A).
[0033] The content of component (C) in the present invention is not particularly limited, but is preferably 0.0001 to 1%, more preferably 0.0005 to 0.5%, and even more preferably 0.001 to 0.2%, based on the total amount of the composition. This range is more preferable because it provides a better masking effect and matching effect against the offensive odor of component (A).
[0034] In the present invention, the mass ratio (A) / (C) of component (A) to component (C) is not particularly limited, but is preferably 5 or more, more preferably 10 or more. Furthermore, the mass ratio (A) / (C) is preferably 2000 or less, more preferably 1000 or less. By setting it in this range, excellent masking effects and matching effects against the offensive odor of stearyl glycyrrhetinate are achieved, and this is more preferred.
[0035] In the present invention, the mass ratio (A) / (C) of component (A) to component (C) is preferably 5 to 2000, more preferably 10 to 1000. This range is more preferable because it provides excellent masking effects and matching effects against the offensive odor of stearyl glycyrrhetinate.
[0036] In addition to the above-mentioned components, the composition of the present invention may contain components used in ordinary cosmetics and topical skin preparations, etc., namely, water (purified water, hot spring water, deep sea water, etc.), surfactants, oils, gelling agents, powders, water-soluble alcohols, water-soluble polymers, film-forming agents, resins, welding compounds, moisturizers, antibacterial agents, fragrances other than component (C), deodorants, salts, chelating agents, ultraviolet absorbers, pH adjusters, cooling agents, plant extracts, vitamins, beauty ingredients, etc., within qualitative and quantitative ranges that do not impair the effects of the present invention.
[0037] The water is not particularly limited, but examples thereof include purified water, distilled water, ion-exchanged water, tap water, hot spring water, deep sea water, etc. In the present invention, the content of water in the composition is not particularly limited, but is preferably 20 to 95%, more preferably 30 to 90%.
[0038] Surfactants include anionic surfactants, cationic surfactants, amphoteric surfactants, and nonionic surfactants (lipophilic and hydrophilic).
[0039] Examples of anionic surfactants include fatty acid soaps (e.g., sodium laurate, sodium palmitate, etc.); higher alkyl sulfates (e.g., sodium lauryl sulfate, potassium lauryl sulfate, etc.); alkyl ether sulfates (e.g., POE-lauryl triethanolamine sulfate, sodium POE-lauryl sulfate, etc.); N-acyl sarcosinates (e.g., sodium lauroyl sarcosinate, etc.); higher fatty acid amide sulfonates (e.g., sodium N-myristoyl-N-methyl taurate, sodium coconut oil fatty acid methyl taurate, sodium stearoyl methyl taurate, sodium lauryl methyl taurate, etc.); sulfosuccinates (e.g., sodium di-2-ethylhexyl sulfosuccinate, sodium monolauroyl monoethanolamide polyoxyethylene sulfosuccinate, sodium lauryl polypropylene glycol ... alkylbenzenesulfonates (for example, linear dodecylbenzenesulfonate sodium, linear dodecylbenzenesulfonate triethanolamine, linear dodecylbenzenesulfonic acid, etc.); higher fatty acid ester sulfate salts (for example, hydrogenated coconut oil fatty acid glycerin sodium sulfate, etc.); N-acylglutamates (for example, N-lauroylglutamic acid monosodium, N-stearoylglutamic acid disodium, N-myristoyl-L-glutamic acid monosodium, etc.); POE-alkyl ether carboxylic acids; POE-alkyl allyl ether carboxylates; α-olefin sulfonates; higher fatty acid ester sulfonates; secondary alcohol sulfate salts; higher fatty acid alkylolamide sulfate salts; lauroylmonoethanolamide sodium succinate; N-palmitoyl aspartic acid ditriethanolamine; sodium caseinate, etc.
[0040] Examples of cationic surfactants include alkyltrimethylammonium salts (e.g., stearyltrimethylammonium chloride, lauryltrimethylammonium chloride, etc.); alkylpyridinium salts (e.g., cetylpyridinium chloride, etc.); dialkyldimethylammonium chloride salts (e.g., distearyldimethylammonium chloride, etc.); poly(N,N'-dimethyl-3,5-methylenepiperidinium) chloride; alkyl quaternary ammonium salts; alkyldimethylbenzylammonium salts; alkylisoquinolinium salts; dialkylmorphonium salts; POE-alkylamines; alkylamine salts; polyamine fatty acid derivatives; amyl alcohol fatty acid derivatives; benzalkonium chloride; benzethonium chloride, etc.
[0041] Examples of amphoteric surfactants include imidazoline-based amphoteric surfactants (e.g., 2-undecyl-N,N,N-(hydroxyethylcarboxymethyl)-2-imidazoline sodium, 2-cocoyl-2-imidazolinium hydroxide-1-carboxyethyloxy disodium salt, etc.); betaine-based surfactants (e.g., 2-heptadecyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, lauryldimethylaminoacetic acid betaine, alkyl betaine, amido betaine, sulfobetaine, etc.); and phospholipids (e.g., lecithin, hydrogenated lecithin, etc.). Lecithin can be derived from soybeans, eggs, etc.
[0042] Examples of lipophilic nonionic surfactants include sorbitan fatty acid esters (e.g., sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, sorbitan trioleate, diglycerol sorbitan penta-2-ethylhexylate, diglycerol sorbitan tetra-2-ethylhexylate, etc.); polyglycerin fatty acid esters (e.g., polyglyceryl-2 triisostearate, polyglyceryl-2 diisostearate, polyglyceryl-3 diisostearate); propylene glycol fatty acid esters (e.g., propylene glycol monostearate, etc.); hydrogenated castor oil derivatives; and glycerin alkyl ethers.
[0043] Examples of hydrophilic nonionic surfactants include POE-sorbitan fatty acid esters (e.g., POE-sorbitan monooleate, POE-sorbitan monostearate, POE-sorbitan tetraoleate, etc.); POE sorbit fatty acid esters (e.g., POE-sorbitan monolaurate, POE-sorbitan monooleate, POE-sorbitan pentaoleate, POE-sorbit monostearate, etc.); POE-glycerin fatty acid esters (e.g., POE-glycerin monostearate, POE-glycerin monoisostearyl ester); POE-monooleates such as POE-glycerol triisostearate, etc.); POE-fatty acid esters (for example, POE-distearate, POE-monodioleate, ethylene glycol distearate, etc.); POE-alkyl ethers (for example, POE-lauryl ether, POE-oleyl ether, POE-stearyl ether, POE-behenyl ether, POE-2-octyldodecyl ether, POE-cholestanol ether, POE-phytosterol ether, etc.); Pluronic types (for example, Pluronic (registered trademark) registered trademark), etc.); POE·POP-alkyl ethers (for example, POE·POP-cetyl ether, POE·POP-2-decyltetradecyl ether, POE·POP-monobutyl ether, POE·POP-hydrogenated lanolin, POE·POP-glycerin ether, etc.); tetraPOE·tetraPOP-ethylenediamine condensates (for example, Tetronic, etc.); POE-castor oil hydrogenated castor oil derivatives (for example, POE-castor oil, POE-hydrogenated castor oil, POE-hydrogenated castor oil monoisostearate, POE-hydrogenated castor oil triisostearate, Examples of the esters include POE-hydrogenated castor oil monopyroglutamic acid monoisostearate diester, POE-hydrogenated castor oil maleic acid, etc.; POE-beeswax / lanolin derivatives (for example, POE-sorbitol beeswax, etc.); alkanolamides (for example, coconut oil fatty acid diethanolamide, lauric acid monoethanolamide, fatty acid isopropanolamide, etc.); POE-propylene glycol fatty acid esters; POE-alkylamines; POE-fatty acid amides; sucrose fatty acid esters; alkylethoxydimethylamine oxide; and trioleyl phosphate.
[0044] As the oil agent, oily components such as higher alcohols, hydrocarbon oils, ester oils, fats and oils, silicones, etc., can be used. For example, higher alcohols such as lauryl alcohol, myristyl alcohol, palmityl alcohol, stearyl alcohol, behenyl alcohol, hexadecyl alcohol, oleyl alcohol, isostearyl alcohol, hexyldodecanol, octyldodecanol, cetostearyl alcohol, 2-decyltetradecynol, cholesterol, phytosterol, sitosterol, lanosterol, monostearyl glycerin ether (batyl alcohol), fatty acids such as isostearic acid and oleic acid, ozokerite, etc. hydrocarbons such as cereals, squalane, squalene, ceresin, paraffin, paraffin wax, liquid paraffin, pristane, polyisobutylene, microcrystalline wax, and petrolatum; diisobutyl adipate, 2-hexyldecyl adipate, di-2-heptylundecyl adipate, N-alkyl glycol monoisostearate, isocetyl isostearate, trimethylolpropane triisostearate, cetyl tri-2-ethylhexanoate, ethylene glycol di-2-ethylhexanoate, and 2-ethylhexanoic acid; Cetyl, trimethylolpropane tri-2-ethylhexanoate, pentaerythritol tetra-2-ethylhexanoate, cetyl octanoate, octyldodecyl gum ester, oleyl oleate, octyldodecyl oleate, decyl oleate, neopentyl glycol dicaprate, triethyl citrate, 2-ethylhexyl succinate, isocetyl stearate, butyl stearate, diisopropyl sebacate, di-2-ethylhexyl sebacate, cetyl lactate, myristyl lactate, isopropyl palmitate, palmitic ester oils such as 2-ethylhexyl myristate, 2-hexyldecyl palmitate, 2-heptylundecyl palmitate, cholesteryl 12-hydroxystearate, dipentaerythritol fatty acid esters, isopropyl myristate, octyldodecyl myristate, 2-hexyldecyl myristate, myristyl myristate, hexyldecyl dimethyloctanoate, ethyl laurate, hexyl laurate, diisostearyl malate, and glyceryl tri-2-ethylhexanoate; beeswax, carnauba wax, candelilla wax;Waxes such as spermaceti, vegetable oils and fats typified by palm oil, palm kernel oil, olive oil, safflower oil, soybean oil, cottonseed oil, etc., animal oils such as beef tallow, beef leg fat, beef bone fat, hardened beef tallow, hardened oil, turtle oil, lard, horse fat, mink oil, liver oil, egg yolk oil, etc., lanolin, liquid lanolin, reduced lanolin, lanolin alcohol, hard lanolin, lanolin acetate, lanolin fatty acid isopropyl, etc., methylpolysiloxane, methylphenylpolysiloxane, decamethylcyclopentasiloxane, octamethylcyclopentasiloxane, etc. Examples of the silicone include polyisotetrasiloxane, polyether-modified polysiloxane, polyoxyalkylene-alkylmethylpolysiloxane-methylpolysiloxane copolymer, alkoxy-modified polysiloxane, alkyl-modified polysiloxane, crosslinked organopolysiloxane, fluorine-modified polysiloxane, amino-modified polysiloxane, glycerin-modified polysiloxane, higher alkoxy-modified silicone, higher fatty acid-modified silicone, silicone resin, silicone rubber, and silicone resin.
[0045] Examples of gelling agents include dextrin fatty acid esters such as dextrin palmitate, dextrin stearate, and dextrin 2-ethylhexanoate palmitate; sucrose fatty acid esters such as sucrose palmitate and sucrose stearate; benzylidene derivatives of sorbitol such as monobenzylidene sorbitol and dibenzylidene sorbitol; inulin derivatives such as inulin stearate; and organically modified clay minerals such as dimethylbenzyldodecylammonium montmorillonite clay and dimethyldioctadecylammonium montmorillonite clay.
[0046] As the powder, any powder used in ordinary cosmetics can be used regardless of its shape (spherical, acicular, plate-like, etc.), particle size (aerosol, fine particles, pigment-grade, etc.), or particle structure (porous, non-porous, etc.). For example, examples of inorganic powders include magnesium oxide, barium sulfate, calcium sulfate, magnesium sulfate, calcium carbonate, magnesium carbonate, talc, synthetic mica, mica, kaolin, sericite, muscovite, synthetic mica, phlogopite, lepidolite, biotite, lepidolite, silicic acid, silicic anhydride, aluminum silicate, magnesium silicate, aluminum silicate, and the like. Examples of organic powders include polyamide powder, polyester powder, polyethylene powder, polypropylene powder, polystyrene powder, polyurethane powder, benzoguanamine powder, polymethylbenzoguanamine powder, tetrafluoroethylene powder, polymethyl methacrylate powder, cellulose powder, silk powder, nylon powder, nylon 12 powder, nylon 6 powder, styrene-acrylic acid copolymer powder, divinylbenzene-styrene copolymer powder, vinyl resin powder, urea resin powder, phenolic resin powder, fluororesin powder, silicon resin powder, acrylic resin powder, melamine resin powder, epoxy resin powder, polycarbonate resin powder, microcrystalline fiber powder, lauroyl lysine, and examples of color pigments include Inorganic red pigments such as iron oxide, iron hydroxide, and iron titanate, inorganic brown pigments such as gamma-iron oxide, inorganic yellow pigments such as yellow iron oxide and ochre, inorganic black pigments such as black iron oxide and carbon black, inorganic purple pigments such as manganese violet and cobalt violet, inorganic green pigments such as chromium hydroxide, chromium oxide, cobalt oxide, and cobalt titanate, inorganic blue pigments such as iron blue and ultramarine, lakes of tar-based pigments, lakes of natural pigments, and composite powders of these powders; pearl pigments include titanium dioxide-coated mica, titanium dioxide-coated mica, bismuth oxychloride,Titanium oxide-coated bismuth oxychloride, titanium oxide-coated talc, fish scale foil, titanium oxide-coated colored mica, etc.; metal powder pigments such as aluminum powder, copper powder, and stainless steel powder; tar dyes such as Red No. 3, Red No. 104, Red No. 106, Red No. 201, Red No. 202, Red No. 204, Red No. 205, Red No. 220, Red No. 226, Red No. 227, Red No. 228, Red No. 230, Red No. 401, Red No. 505, Yellow No. 4, Yellow No. 5, and Yellow 202 No. 203, Yellow No. 204, Yellow No. 401, Blue No. 1, Blue No. 2, Blue No. 201, Blue No. 404, Green No. 3, Green No. 201, Green No. 204, Green No. 205, Orange No. 201, Orange No. 203, Orange No. 204, Orange No. 206, Orange No. 207, etc. Natural pigments include powders selected from carminic acid, laccaic acid, carthamine, brazilian, crocin, etc., and may be composites of these powders or powders surface-treated with oils, silicones, fluorine compounds, etc.
[0047] Examples of water-soluble alcohols include lower alcohols such as ethanol and isopropanol, and polyhydric alcohols such as glycerin, diglycerin, ethylene glycol, diethylene glycol, triethylene glycol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, and polyethylene glycol.
[0048] Examples of water-soluble polymers include mucopolysaccharides selected from chondroitin sulfate, hyaluronic acid, mucin, dermatan sulfate, heparin, and keratan sulfate, and salts thereof; plant-based polymers such as gum arabic, tragacanth, galactan, carob gum, guar gum, karaya gum, carrageenan, pectin, agar, quince seed, algae colloid, toranth gum, locust bean gum, and galactomannan; microbial polymers such as xanthan gum, dextran, succinoglucan, and pullulan; starch-based polymers such as starch, carboxymethyl starch, and methylhydroxypropyl starch; methylcellulose, ethylcellulose, and the like. Examples of anionic polymers include cellulose, methylhydroxypropyl cellulose, carboxymethyl cellulose, hydroxymethyl cellulose, hydroxypropyl cellulose, nitrocellulose, sodium cellulose sulfate, sodium carboxymethyl cellulose, crystalline cellulose, and cellulose; alginate polymers, such as sodium alginate and propylene glycol alginate; vinyl polymers, such as polyvinyl methyl ether; polyoxyethylene polymers, polyoxyethylene-polyoxypropylene copolymer polymers; and inorganic water-soluble polymers, such as bentonite, laponite, and hectorite. Examples of anionic polymers include carboxyvinyl polymers, acrylic acid / alkyl methacrylate copolymers, sodium acrylate / sodium acryloyldimethyl taurate copolymers, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymers, (acrylates / beheneth-25 methacrylate) copolymers, acrylic acid / ethyl acrylate / N-tert-butylacrylamide copolymers, acrylic resin alkanolamines, vinyl methyl ether / ethyl maleate copolymers, vinyl methyl ether / butyl maleate copolymers, and vinyl acetate / crotonic acid copolymers.Examples of amphoteric polymers include N-methacryloylethyl N,N-dimethylammonium-α-N-methylcarboxybetaine-alkyl methacrylate copolymers, hydroxypropyl acrylate-butylaminoethyl methacrylate-octyl acrylate copolymers, acrylic acid-dimethyldiallylammonium chloride-acrylamide copolymers, and dimethyldiallylammonium chloride-acrylic acid copolymers. Examples of cationic polymers include vinylpyrrolidone-N,N-dimethylaminoethyl methacrylate copolymer diethyl sulfate, diallyldimethylammonium chloride-hydroxyethylcellulose, glycidyltrimethylammonium chloride-hydroxyethylcellulose, dimethyldiallylammonium chloride polymers, and dimethyldiallylammonium chloride-acrylamide copolymers. Examples of nonionic polymers include polyvinylpyrrolidone, vinylpyrrolidone-vinyl acetate copolymers, polyvinyl alcohol, and polyurethane.
[0049] Examples of antibacterial agents include benzoic acid, sodium benzoate, salicylic acid, carbolic acid, sorbic acid, potassium sorbate, parachlormetacresol, hexachlorophene, benzalkonium chloride, chlorhexidine chloride, trichlorocarbanilide, photosensitizers, zinc bis(2-pyridylthio-1-oxide), isopropylmethylphenol, and glyceryl caprylate. Examples of preservatives include parahydroxybenzoate and phenoxyethanol.
[0050] Examples of vitamins include vitamin A and derivatives thereof, vitamin B and derivatives thereof, vitamin C and derivatives thereof, vitamin E and derivatives thereof, vitamin F such as linoleic acid and derivatives thereof, vitamin K such as phytonadione, menaquinone, menadione, and menadiol, vitamin P such as eriocitrin and hesperidin, biotin, carnitine, and ferulic acid.
[0051] The form of the composition of the present invention is not particularly limited, and examples thereof include liquid, gel, emulsion, cream, semi-solid, and solid forms.
[0052] The formulation of the composition is not particularly limited, and examples thereof include water-based, oil-based, solubilized, oil-in-water, water-in-oil, water-in-oil-in-water, oil-in-water-in-oil, and multi-layer formulations.
[0053] The composition of the present invention may be used as a final preparation as it is, or may be a part of the composition and further mixed with other ingredients to form a final preparation.Here, examples of the final preparation include cosmetics, external skin preparations, pharmaceutical preparations, etc.Specific examples include hair cosmetics such as hair tonic, hair cream, shampoo, rinse, conditioner, hair styling agent, etc.; skin care cosmetics such as lotion, emulsion, cream, serum, lip balm, hand cream, face wash, cleanser, solid perfume, etc.; makeup cosmetics such as foundation, makeup base, blusher, eye shadow, mascara, eyeliner, eyebrow, overcoat, lipstick, lip gloss, etc.; fragrance cosmetics such as perfume, solid perfume, eau de parfum, eau de toilette, eau de cologne, light cologne, fresh cologne, perfume lotion, etc.; external skin preparations such as dispersion, ointment, lotion, aerosol, patch, cataplasm, liniment, etc.; pharmaceutical preparations such as mouthwash, nasal drops, cold medicine, etc. In the present invention, the final formulation is preferably a cosmetic or an external skin preparation.
[0054] The content of the composition of the present invention contained in the cosmetic or external skin preparation is not particularly limited, but is preferably 0.001 to 90%.
[0055] Furthermore, in cosmetics or topical skin preparations containing component (A) stearyl glycyrrhetinate, the cosmetics or topical skin preparations preferably contain at least an oily agent, from the viewpoint of being able to more effectively exhibit odor-improving effects (masking effect, matching effect, lasting effect, etc.). The content of the oily agent in the cosmetics or topical skin preparations is not particularly limited, but is preferably 2% or more, more preferably 5% or more. The upper limit of the oily agent content is not particularly limited, but is usually preferably 20% or less.
[0056] In addition to the above-mentioned components, the cosmetic or topical skin preparation may contain components that are commonly used in cosmetic or topical skin preparations, etc., within qualitative and quantitative ranges that do not impair the effects of the present invention. Although details of each component will be omitted as appropriate, the explanations for the composition above also apply to the cosmetic or topical skin preparation and can be adopted as appropriate.
[0057] The form of the cosmetic or external skin preparation is not particularly limited, and examples include liquid, gel, emulsion, cream, semi-solid, and solid forms.
[0058] Furthermore, the formulation of the cosmetic or topical skin preparation is not particularly limited, and examples thereof include water-based, oil-based, solubilized, oil-in-water, water-in-oil, water-in-oil-in-water, oil-in-water-in-oil, and multi-layered formulations, with solubilized, oil-in-water, and water-in-oil formulations being preferred, and oil-in-water formulations being more preferred.
[0059] In the cosmetic or topical skin preparation containing component (A) of the present invention, component (C) is more preferably at least one selected from the group consisting of components (1) to (3), (7) to (12), (14) to (16), (23) to (27), (29) to (33), (35) to (40), (44), and (45) in Table 1. By setting it within this range, it is more preferable because it has a better masking effect against the offensive odor of component (A), a better matching effect, and a better lasting effect.
[0060] In the cosmetic or topical skin preparation containing component (A) of the present invention, from the viewpoint of achieving a more excellent masking effect, component (C) is more preferably at least one selected from the group consisting of components (1), (2), (10) to (12), (14), (23), (27), (29) to (32), (36), (38), (39), and (45) in Table 1.
[0061] In the cosmetic or topical skin preparation containing component (A) of the present invention, from the viewpoint of achieving a more excellent matching effect, component (C) is more preferably at least one selected from the group consisting of components (1), (9), (10), (15), (25), (27), (30), (36), (38), and (45) in Table 1.
[0062] In the cosmetic or topical skin preparation containing component (A) of the present invention, from the viewpoint of achieving a more excellent lasting effect, component (C) is more preferably at least one selected from the group consisting of components (1), (2), (9) to (12), (14) to (16), (30), (31), (35), (37), and (39) in Table 1.
[0063] In the cosmetic or topical skin preparation containing component (A) of the present invention, from the viewpoint of achieving a superior masking effect and matching effect, component (C) is more preferably at least one selected from the group consisting of components (1), (10), (27), (30), (36), (38), and (45) in Table 1.
[0064] In the cosmetic or topical skin preparation containing component (A) of the present invention, from the viewpoint of achieving a more excellent masking effect and lasting effect, component (C) is more preferably at least one selected from the group consisting of components (1), (2), (10) to (12), (14), (30), (31), and (39) in Table 1.
[0065] In the cosmetic or topical skin preparation containing component (A) of the present invention, from the viewpoint of achieving superior matching and lasting effects, component (C) is more preferably at least one selected from the group consisting of components (1), (9), (10), (15), and (30) in Table 1.
[0066] In the cosmetic or topical skin preparation containing component (A) of the present invention, component (C) is more preferably at least one selected from the group consisting of components (1), (10), and (30) in Table 1, from the viewpoint of achieving superior masking effect, matching effect, and lasting effect.
[0067] In the cosmetic or external skin preparation, the content of component (A) of the present invention is not particularly limited, but is preferably 0.01% or more, more preferably 0.05% or more, based on the total amount of the cosmetic or external skin preparation.Moreover, it is preferably 5% or less, more preferably 1% or less, and even more preferably 0.5% or less.By making it in this range, it is more preferable because it can exhibit various skin effects of stearyl glycyrrhetinate, and also has better masking effect, matching effect and lasting effect.
[0068] In the cosmetic or topical skin preparation, the content of component (A) of the present invention is not particularly limited, but is preferably 0.01 to 5%, more preferably 0.05 to 1%, and even more preferably 0.05 to 0.5%, based on the total amount of the cosmetic or topical skin preparation. This range is more preferable because it allows the various skin benefits of stearyl glycyrrhetinate to be exerted while also providing superior masking effect, matching effect, and lasting effect.
[0069] In cosmetics or topical skin preparations, the content of component (B) of the present invention is not particularly limited, but is preferably 0.005% or more, more preferably 0.01% or more, even more preferably 0.1% or more, even more preferably 0.5% or more, particularly preferably 1% or more, and more preferably 2% or more, based on the total amount of cosmetics or topical skin preparations.Moreover, it is preferably 10% or less, more preferably 8% or less, and even more preferably 6% or less.By making it in this range, it can ensure good masking effect, matching effect and lasting effect, and can be excellent in various skin effects of niacinamide, so it is more preferable.
[0070] In the cosmetic or topical skin preparation, the content of component (B) of the present invention is not particularly limited, but is preferably 0.005 to 10%, more preferably 0.01 to 10%, even more preferably 0.1 to 10%, even more preferably 0.5 to 8%, particularly preferably 1 to 8%, and more preferably 2 to 6%, based on the total amount of the cosmetic or topical skin preparation. This range is more preferable because it ensures good masking effect, matching effect, and lasting effect while providing various excellent skin effects of niacinamide.
[0071] In the cosmetic or topical skin preparation, the content mass ratio (A) / (B) of component (A) to component (B) is not particularly limited, but is preferably 10 or less, more preferably 5 or less, even more preferably 1 or less, even more preferably 0.5 or less, particularly preferably 0.3 or less, and more preferably 0.1 or less. The content mass ratio (A) / (B) is preferably 0.001 or more, more preferably 0.005 or more, and even more preferably 0.01 or more. By setting it within this range, various skin effects of niacinamide are excellent while ensuring good masking effect, matching effect, and lasting effect, and is therefore more preferable.
[0072] In the cosmetic or topical skin preparation, the mass ratio (A) / (B) of component (A) to component (B) is preferably 0.001 to 10, more preferably 0.005 to 5, even more preferably 0.005 to 1, even more preferably 0.01 to 0.5, particularly preferably 0.01 to 0.3, and more preferably 0.01 to 0.1. By setting the mass ratio within this range, various skin effects of niacinamide are excellent while ensuring a good masking effect, matching effect, and lasting effect, and this is more preferable.
[0073] In cosmetics or topical skin preparations, the content of component (C) of the present invention is not particularly limited, but is preferably 0.00001% or more, more preferably 0.00005% or more, based on the total amount of cosmetics or topical skin preparations.Moreover, it is preferably 1% or less, more preferably 0.5% or less, even more preferably 0.1% or less, and even more preferably 0.05% or less.By making it in this range, it is more preferable because it can exhibit various skin effects of stearyl glycyrrhetinate, and also has better masking effect, matching effect and lasting effect.
[0074] In the cosmetic or topical skin preparation, the content of component (C) of the present invention is not particularly limited, but is preferably 0.00001 to 1%, more preferably 0.00005 to 0.5%, even more preferably 0.00005 to 0.1%, and even more preferably 0.00005 to 0.05%, based on the total amount of the cosmetic or topical skin preparation. By setting the content within this range, the various skin effects of stearyl glycyrrhetinate can be exhibited while the masking effect, matching effect, and lasting effect are more excellent, which is more preferable.
[0075] In the cosmetic or topical skin preparation, the mass ratio (A) / (C) of component (A) to component (C) is preferably 5 to 2000, more preferably 10 to 1000. By setting it within this range, the various skin effects of stearyl glycyrrhetinate can be exhibited while the masking effect, matching effect, and lasting effect are more excellent, which is more preferable.
[0076] (Production Method) The composition of the present embodiment is not particularly limited and can be prepared by a conventional method. For example, it can be obtained by dissolving component (A) in a solvent such as dipropylene glycol, and then adding and mixing component (C) and component (B) dissolved in water.
[0077] In another aspect of the present invention, there is provided a method for improving the offensive odor of a composition containing component (A) stearyl glycyrrhetinate and component (B) niacinamide, the method comprising the step of: Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetateAcetate), α-Terpineol, Geraniol, Geranyl Acetate, Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate and a method for improving an offensive odor, which uses at least one selected from the group consisting of methyl 2-octynoate, ...
[0078] In the explanation of the above-mentioned method for improving odors, explanations of components (A) to (C), their respective contents, their respective mass proportions, manufacturing methods, respective configurations, respective methods, respective terms, etc. will be omitted as appropriate, but the explanations for the composition described above also apply to this method and can be adopted as appropriate.
[0079] The odor improving method of the present invention is preferably a method for deodorizing a composition containing component (A) and component (B), and more preferably a method for deodorizing component (A) enhanced by the incorporation of component (B).
[0080] In another aspect of the present invention, there is provided an odor improving agent for improving the odor of a composition containing component (A) stearyl glycyrrhetinate and component (B) niacinamide, the odor improving agent including component (C) anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetateAcetate), α-Terpineol, Geraniol, Geranyl Acetate, Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate The present invention can be used as an odor improving agent containing at least one active ingredient selected from the group consisting of methyl 2-octynoate, ...
[0081] In the description of the odor improving agent, explanations of the components (A) to (C), their respective contents, their respective mass proportions, manufacturing methods, respective configurations, respective methods, respective terms, etc. will be omitted as appropriate, but the explanations of the composition described above also apply to this agent and can be adopted as appropriate.
[0082] The odor improving agent of the present invention is preferably a deodorizing agent of a composition containing component (A) and component (B), and more preferably a deodorizing agent of component (A) enhanced by the incorporation of component (B).
[0083] A composition according to a second embodiment of the present invention will now be described. The composition according to the second embodiment contains component (A) stearyl glycyrrhetinate, component (B) tranexamic acid, and component (C) a fragrance component. In the description of the second embodiment, the description of the first embodiment will be used to refer to aspects similar to those of the first embodiment, and the description may be omitted.
[0084] <Component (A)> In the composition according to the second embodiment, component (A) is the same as in the first embodiment.
[0085] <Component (B)> Tranexamic acid, the component (B) used in the present invention, is a type of amino acid with the chemical name trans-4-(aminomethyl)cyclohexane-1-carboxylic acid, and is known as a component that has skin-whitening and anti-inflammatory effects as described above, and is also sometimes used as a hemostatic agent.
[0086] The content of component (B) in the present invention is not particularly limited, but is preferably 0.1% or more, more preferably 0.5% or more, and even more preferably 1% or more, based on the total amount of the composition. It is also preferably 10% or less, more preferably 5% or less, and even more preferably 3% or less. This range is more preferable because it ensures good masking and matching effects while providing excellent skin benefits of tranexamic acid.
[0087] The content of component (B) in the present invention is not particularly limited, but is preferably 0.1 to 10%, more preferably 0.5 to 5%, and even more preferably 1 to 3%, of the total amount of the composition. This range is more preferable because it ensures good masking and matching effects while providing excellent skin benefits of tranexamic acid.
[0088] In the present invention, the mass ratio (A) / (B) of component (A) to component (B) is not particularly limited, but is preferably 1 or less, more preferably 0.5 or less, and even more preferably 0.3 or less. Furthermore, the mass ratio (A) / (B) is preferably 0.001 or more, more preferably 0.005 or more, even more preferably 0.01 or more, and particularly preferably 0.02 or more. By setting it within this range, the various skin effects of tranexamic acid are excellent while ensuring good masking and matching effects, and this is more preferable.
[0089] In the present invention, the mass ratio (A) / (B) of component (A) to component (B) is preferably 0.001 to 1, more preferably 0.005 to 0.5, even more preferably 0.01 to 0.5, even more preferably 0.01 to 0.3, and particularly preferably 0.02 to 0.3. This range is more preferable because it ensures good masking and matching effects while providing excellent skin benefits of tranexamic acid.
[0090] <Component (C)> Component (C) used in the present invention is a fragrance component for improving the offensive odor of component (A), stearyl glycyrrhetinate.Component (C) includes anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super, sandalore, ambroxan, γ-terpinene, ambrettolide, β-ionone, borneol, and isobutylquinoline. Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal The masking agent is at least one selected from the group consisting of benzyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, and heliotropine, and has excellent masking, matching, and lasting effects (see Table 2).In the following, the component name of component (C) may be indicated by the number shown in Table 1.
[0091]
[0092] Component (C) may be hydrocarbons such as α-pinene and γ-terpinene, alcohols such as linalool, citronellol, α-terpineol, farnesol, borneol, patchouli alcohol, cedrol, anise alcohol, 1-hexanol, eugenol, guaiacol, sandaloa, mayol, nerol, dimethylbenzylcarbinol, bacdanol, and phenylethyl alcohol, ambroxan, magnolan, and phenylacetaldehyde dimethyl acetal. ethers, aldehydes such as citral, ethyl vanillin, anisaldehyde, benzaldehyde, and heliotropin; ketones such as β-ionone, maltol, Iso-E-Super, damascenone, and mucenone; esters such as cedryl acetate, linalyl acetate, benzyl benzoate, methyl anthranilate, benzyl acetate, and phenylethyl acetate; synthetic musks such as ambretride; and nitrogen-containing compounds such as isobutylquinoline.
[0093] In the present invention, from the viewpoint of excellent masking effect against the offensive odor of component (A), component (C) is more preferably at least one selected from the group consisting of components (1) to (20), (23) to (31), and (33) to (39) in Table 2, and more preferably at least one selected from the group consisting of components (2), (3), (8) to (11), (15), (18), (25), (27), (31), (36), and (37) in Table 2.
[0094] In the present invention, from the viewpoint of achieving an excellent matching effect against the odor of component (A), component (C) is preferably at least one selected from the group consisting of components (1) to (40) in Table 2, and more preferably at least one selected from the group consisting of components (1), (3), (9), (10), (15), (18), (20), (25), (28), (34), and (36) in Table 2.
[0095] In the present invention, from the viewpoint of achieving a superior masking effect and matching effect against the odor of component (A), it is more preferable that component (C) be at least one selected from the group consisting of components (3), (9), (10), (15), (18), (25), and (36) in Table 2.
[0096] The content of component (C) in the present invention is not particularly limited, but is preferably 0.0001% or more, more preferably 0.0005% or more, and even more preferably 0.001% or more, based on the total amount of composition.Moreover, it is preferably 1% or less, more preferably 0.5% or less, and even more preferably 0.2% or less.By making it in this range, it is more preferable because it has better masking effect and matching effect against the odor of component (A).
[0097] The content of component (C) in the present invention is not particularly limited, but is preferably 0.0001 to 1%, more preferably 0.0005 to 0.5%, and even more preferably 0.001 to 0.2%, based on the total amount of the composition. This range is more preferable because it provides a better masking effect and matching effect against the offensive odor of component (A).
[0098] In the present invention, the mass ratio (A) / (C) of component (A) to component (C) is not particularly limited, but is preferably 5 or more, more preferably 10 or more. Furthermore, the mass ratio (A) / (C) is preferably 2000 or less, more preferably 1000 or less. By setting it in this range, excellent masking effects and matching effects against the offensive odor of stearyl glycyrrhetinate are achieved, and this is more preferred.
[0099] In the present invention, the mass ratio (A) / (C) of component (A) to component (C) is preferably 5 to 2000, more preferably 10 to 1000. This range is more preferable because it provides excellent masking effects and matching effects against the offensive odor of stearyl glycyrrhetinate.
[0100] In addition to the above components, the composition of the present invention may contain components used in ordinary cosmetics and topical skin preparations, etc., within qualitative and quantitative ranges that do not impair the effects of the present invention, namely, water (purified water, hot spring water, deep sea water, etc.), surfactants, oils, gelling agents, powders, water-soluble alcohols, water-soluble polymers, film-forming agents, resins, welding compounds, moisturizers, antibacterial agents, fragrances other than component (C), deodorants, salts, chelating agents, UV absorbers, pH adjusters, cooling agents, plant extracts, vitamins, cosmetic ingredients, etc. Specific examples and contents of each of the above components are the same as those in the first embodiment.
[0101] The form of the composition of the present invention is not particularly limited, and examples thereof include liquid, gel, emulsion, cream, semi-solid, and solid forms.
[0102] The formulation of the composition is not particularly limited, and examples thereof include water-based, oil-based, solubilized, oil-in-water, water-in-oil, water-in-oil-in-water, oil-in-water-in-oil, and multi-layer formulations.
[0103] The composition of the present invention may be used as a final preparation as it is, or may be a part of the composition and further mixed with other ingredients to form a final preparation.Here, examples of the final preparation include cosmetics, external skin preparations, pharmaceutical preparations, etc.Specific examples include hair cosmetics such as hair tonic, hair cream, shampoo, rinse, conditioner, hair styling agent, etc.; skin care cosmetics such as lotion, emulsion, cream, serum, lip balm, hand cream, face wash, cleanser, solid perfume, etc.; makeup cosmetics such as foundation, makeup base, blusher, eye shadow, mascara, eyeliner, eyebrow, overcoat, lipstick, lip gloss, etc.; fragrance cosmetics such as perfume, solid perfume, eau de parfum, eau de toilette, eau de cologne, light cologne, fresh cologne, perfume lotion, etc.; external skin preparations such as dispersion, ointment, lotion, aerosol, patch, cataplasm, liniment, etc.; pharmaceutical preparations such as mouthwash, nasal drops, cold medicine, etc. In the present invention, the final formulation is preferably a cosmetic or an external skin preparation.
[0104] The content of the composition of the present invention contained in the cosmetic or external skin preparation is not particularly limited, but is preferably 0.001 to 90%.
[0105] Furthermore, in cosmetics or topical skin preparations containing component (A) stearyl glycyrrhetinate, the cosmetics or topical skin preparations preferably contain at least an oily agent, from the viewpoint of being able to more effectively exhibit odor-improving effects (masking effect, matching effect, lasting effect, etc.). The content of the oily agent in the cosmetics or topical skin preparations is not particularly limited, but is preferably 2% or more, more preferably 5% or more. The upper limit of the oily agent content is not particularly limited, but is usually preferably 20% or less.
[0106] In addition to the above-mentioned components, the cosmetic or topical skin preparation may contain components that are commonly used in cosmetic or topical skin preparations, etc., within qualitative and quantitative ranges that do not impair the effects of the present invention. Although details of each component will be omitted as appropriate, the explanations for the composition above also apply to the cosmetic or topical skin preparation and can be adopted as appropriate.
[0107] The form of the cosmetic or external skin preparation is not particularly limited, and examples include liquid, gel, emulsion, cream, semi-solid, and solid forms.
[0108] Furthermore, the formulation of the cosmetic or topical skin preparation is not particularly limited, and examples thereof include water-based, oil-based, solubilized, oil-in-water, water-in-oil, water-in-oil-in-water, oil-in-water-in-oil, and multi-layered formulations, with solubilized, oil-in-water, and water-in-oil formulations being preferred, and oil-in-water formulations being more preferred.
[0109] In the cosmetic or topical skin preparation containing component (A) of the present invention, component (C) is more preferably at least one selected from the group consisting of components (1) to (3), (5), (7) to (12), (14) to (16), (23) to (25), (27) to (31), and (33) to (39) in Table 2. This range is more preferable because it provides superior masking effects, matching effects, and lasting effects against the offensive odor of component (A).
[0110] In the cosmetic or topical skin preparation containing component (A) of the present invention, from the viewpoint of achieving a more excellent masking effect, component (C) is more preferably at least one selected from the group consisting of components (1), (2), (8) to (11), (16), (25), (27) to (31), and (35) to (38) in Table 2.
[0111] In the cosmetic or topical skin preparation containing component (A) of the present invention, from the viewpoint of achieving a more excellent matching effect, component (C) is more preferably at least one selected from the group consisting of components (1), (9), (10), (15), (24), (27), (34), and (36) in Table 2.
[0112] In the cosmetic or topical skin preparation containing component (A) of the present invention, from the viewpoint of achieving a more excellent lasting effect, component (C) is more preferably at least one selected from the group consisting of components (1), (2), (8) to (12), (14), (15), (24), (25), (29), (30), (34), (36), and (38) in Table 2.
[0113] In the cosmetic or topical skin preparation containing component (A) of the present invention, component (C) is more preferably at least one selected from the group consisting of components (1), (9), (10), (27), and (36) in Table 2, from the viewpoint of achieving superior masking and matching effects.
[0114] In the cosmetic or topical skin preparation containing component (A) of the present invention, from the viewpoint of achieving a more excellent masking effect and lasting effect, component (C) is more preferably at least one selected from the group consisting of components (1), (2), (8) to (11), (25), (29), (30), (36), and (38) in Table 2.
[0115] In the cosmetic or topical skin preparation containing component (A) of the present invention, from the viewpoint of achieving superior matching and lasting effects, it is more preferable that component (C) be at least one selected from the group consisting of components (1), (9), (10), (15), (24), (34), and (36) in Table 2.
[0116] In the cosmetic or topical skin preparation containing component (A) of the present invention, component (C) is more preferably at least one selected from the group consisting of components (1), (9), (10), and (36) in Table 2, from the viewpoint of achieving superior masking effect, matching effect, and lasting effect.
[0117] In the cosmetic or external skin preparation, the content of component (A) of the present invention is not particularly limited, but is preferably 0.01% or more, more preferably 0.05% or more, based on the total amount of the cosmetic or external skin preparation.Moreover, it is preferably 5% or less, more preferably 1% or less, and even more preferably 0.5% or less.By making it in this range, it is more preferable because it can exhibit various skin effects of stearyl glycyrrhetinate, and also has better masking effect, matching effect and lasting effect.
[0118] In the cosmetic or topical skin preparation, the content of component (A) of the present invention is not particularly limited, but is preferably 0.01 to 5%, more preferably 0.05 to 1%, and even more preferably 0.05 to 0.5%, based on the total amount of the cosmetic or topical skin preparation. This range is more preferable because it allows the various skin benefits of stearyl glycyrrhetinate to be exerted while also providing superior masking effect, matching effect, and lasting effect.
[0119] In the cosmetic or topical skin preparation, the content of component (B) of the present invention is not particularly limited, but is preferably 0.1% or more, more preferably 0.5% or more, and even more preferably 1% or more, based on the total amount of the cosmetic or topical skin preparation. Also, it is preferably 10% or less, more preferably 5% or less, and even more preferably 3% or less. By setting it in this range, various skin effects of tranexamic acid are excellent while ensuring good masking effect, matching effect, and lasting effect, and it is more preferable.
[0120] In the cosmetic or topical skin preparation, the content of component (B) of the present invention is not particularly limited, but is preferably 0.1 to 10%, more preferably 0.5 to 5%, and even more preferably 1 to 3%, based on the total amount of the cosmetic or topical skin preparation. This range is more preferable because it ensures good masking effect, matching effect, and lasting effect while providing excellent skin effects of tranexamic acid.
[0121] In the cosmetic or topical skin preparation, the mass ratio (A) / (B) of component (A) to component (B) is not particularly limited, but is preferably 1 or less, more preferably 0.5 or less, and even more preferably 0.3 or less. Furthermore, the mass ratio (A) / (B) is preferably 0.001 or more, more preferably 0.005 or more, even more preferably 0.01 or more, and particularly preferably 0.02 or more. By setting it within this range, the various skin effects of tranexamic acid are excellent while ensuring good masking effect, matching effect, and lasting effect, and is therefore more preferable.
[0122] In the cosmetic or topical skin preparation, the mass ratio (A) / (B) of component (A) to component (B) is preferably 0.001 to 1, more preferably 0.005 to 0.5, even more preferably 0.01 to 0.5, even more preferably 0.01 to 0.3, and particularly preferably 0.02 to 0.3. This range is more preferable because it ensures good masking effect, matching effect, and lasting effect while providing various excellent skin effects of tranexamic acid.
[0123] In cosmetics or topical skin preparations, the content of component (C) of the present invention is not particularly limited, but is preferably 0.00001% or more, more preferably 0.00005% or more, based on the total amount of cosmetics or topical skin preparations.Moreover, it is preferably 1% or less, more preferably 0.5% or less, even more preferably 0.1% or less, and even more preferably 0.05% or less.By making it in this range, it is more preferable because it can exhibit various skin effects of stearyl glycyrrhetinate, and also has better masking effect, matching effect and lasting effect.
[0124] In the cosmetic or topical skin preparation, the content of component (C) of the present invention is not particularly limited, but is preferably 0.00001 to 1%, more preferably 0.00005 to 0.5%, even more preferably 0.00005 to 0.1%, and even more preferably 0.00005 to 0.05%, based on the total amount of the cosmetic or topical skin preparation. By setting the content within this range, the various skin effects of stearyl glycyrrhetinate can be exhibited while the masking effect, matching effect, and lasting effect are more excellent, which is more preferable.
[0125] In the cosmetic or topical skin preparation, the mass ratio (A) / (C) of component (A) to component (C) is not particularly limited, but is preferably 5 or more, more preferably 10 or more. The mass ratio (A) / (C) is preferably 2000 or less, more preferably 1000 or less. By setting it in this range, the various skin effects of stearyl glycyrrhetinate can be exhibited while the masking effect, matching effect, and lasting effect are more excellent, which is more preferable.
[0126] In the cosmetic or topical skin preparation, the mass ratio (A) / (C) of component (A) to component (C) is preferably 5 to 2000, more preferably 10 to 1000. By setting it within this range, the various skin effects of stearyl glycyrrhetinate can be exhibited while the masking effect, matching effect, and lasting effect are more excellent, which is more preferable.
[0127] (Production Method) The composition of the present embodiment is not particularly limited and can be prepared by a conventional method. For example, it can be obtained by dissolving component (A) in a solvent such as dipropylene glycol, and then adding and mixing component (C) and component (B) dissolved in water.
[0128] In another aspect of the present invention, there is provided a method for improving the offensive odor of a composition containing component (A) stearyl glycyrrhetinate and component (B) tranexamic acid, the method comprising the step of: Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate, Muscenone, Benzyl Acetate, Phenylethyl Alcohol alcohol), phenylethyl acetate,and heliotropine.
[0129] In the explanation of the above-mentioned method for improving odors, explanations of components (A) to (C), their respective contents, their respective mass proportions, manufacturing methods, respective configurations, respective methods, respective terms, etc. will be omitted as appropriate, but the explanations for the composition described above also apply to this method and can be adopted as appropriate.
[0130] The odor improving method of the present invention is preferably a method for deodorizing a composition containing component (A) and component (B), and more preferably a method for deodorizing component (A) enhanced by the incorporation of component (B).
[0131] In another aspect of the present invention, there is provided an odor improving agent for improving the odor of a composition containing component (A) stearyl glycyrrhetinate and component (B) tranexamic acid, the odor improving agent including component (C) anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate, Muscenone, Benzyl Acetate, Phenylethyl Alcohol alcohol), phenylethyl acetate,and heliotropine as an active ingredient, and can be used as an odor improving agent.
[0132] In the description of the odor improving agent, explanations of the components (A) to (C), their respective contents, their respective mass proportions, manufacturing methods, respective configurations, respective methods, respective terms, etc. will be omitted as appropriate, but the explanations of the composition described above also apply to this agent and can be adopted as appropriate.
[0133] The odor improving agent of the present invention is preferably a deodorizing agent of a composition containing component (A) and component (B), and more preferably a deodorizing agent of component (A) enhanced by the incorporation of component (B).
[0134] The present invention can also employ the following configurations: <1> A method for improving the odor of a composition containing stearyl glycyrrhetinate and niacinamide or tranexane, comprising adding an anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), or a combination thereof to the composition. Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate, Muscenone, Benzyl Acetate, Phenylethyl Alcohol alcohol), phenylethyl acetate,<2> A method for improving the odor of a composition containing stearyl glycyrrhetinate and tranexamic acid, comprising adding an anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexanol, linalool, cedryl acetate, Iso E Super (Iso E Super), or methylparaben. Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate, Muscenone, Benzyl Acetate, Phenylethyl Alcohol alcohol), phenylethyl acetate,<3> A method for improving the odor of a composition containing stearyl glycyrrhetinate and niacinamide, comprising adding an anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), or niacinamide to the composition. Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Geraniol, Geranyl acetate Acetate), Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate, Muscenone, Benzyl Acetate,The method for improving an offensive odor comprises adding at least one selected from the group consisting of phenylethyl alcohol, phenylethyl acetate, heliotropine, damascone, benzyl alcohol, and methyl 2-octynoate. <4> An odor improving agent for improving the odor of a composition containing stearyl glycyrrhetinate and niacinamide or tranexamic acid, the odor improving agent comprising anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexanol, linalool, cedryl acetate, Iso E Super (Iso E Super), Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate), damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol,The odor improving agent contains at least one active ingredient selected from the group consisting of bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, and heliotropine. <5> An odor improving agent for improving the odor of a composition containing stearyl glycyrrhetinate and tranexamic acid, the odor improving agent comprising anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate), damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol,The odor improving agent contains at least one active ingredient selected from the group consisting of bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, and heliotropine. <6> An odor improving agent for improving the odor of a composition containing stearyl glycyrrhetinate and niacinamide, the odor improving agent comprising anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Geraniol, Geranyl acetate Acetate), Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal,The offensive odor improving agent contains, as an active ingredient, at least one selected from the group consisting of nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, heliotropine, damascone, benzyl alcohol, and methyl 2-octynoate. <7> The following ingredients (A) to (C): (A) stearyl glycyrrhetinate, (B) niacinamide or tranexamic acid, (C) anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate), damascenone, anisaldehyde, benzaldehyde,At least one selected from the group consisting of Magnolan, Mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, and heliotropine. <8> A composition for improving an odor containing stearyl glycyrrhetinate and niacinamide or tranexamic acid, comprising the following components (A) to (C): (A) stearyl glycyrrhetinate, (B) tranexamic acid, and (C) anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, and Iso E Super (Iso E Super). Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate Benzoate), damascenone, anisaldehyde,At least one selected from the group consisting of benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, and heliotropine. <9> A composition for improving an odor containing stearyl glycyrrhetinate and tranexamic acid, comprising the following components (A) to (C): (A) stearyl glycyrrhetinate, (B) niacinamide, (C) anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, and Iso E Super (Iso E Super). Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Geraniol, Geranyl acetate acetate),Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate, Muscenone, Benzyl Acetate, Phenylethyl Alcohol The present invention relates to a composition for improving an offensive odor, which comprises stearyl glycyrrhetinate and niacinamide, and which contains at least one member selected from the group consisting of phenylalanine, phenylethyl acetate, heliotropin, damascone, benzyl alcohol, and methyl 2-octynoate. <10> The following ingredients (A) to (C): (A) stearyl glycyrrhetinate, (B) niacinamide or tranexamic acid, (C) anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol,Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethyl Benzyl Carbinol The composition contains at least one selected from the group consisting of benzophenone, benzoyl benzoate, ... <11> The following ingredients (A) to (C): (A) stearyl glycyrrhetinate, (B) tranexamic acid, (C) anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol,Ethyl vanillin, maltol, linalyl acetate, α-terpineol, benzyl benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol The composition contains at least one selected from the group consisting of benzophenone, benzoyl benzoate, ... <12> The following ingredients (A) to (C): (A) stearyl glycyrrhetinate, (B) niacinamide, (C) anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-ionone, Borneol, Isobutylquinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol,Ethyl vanillin, maltol, linalyl acetate, α-terpineol, geraniol, geranyl acetate, benzyl benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethylbenzyl carbinol The composition contains at least one selected from the group consisting of benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, heliotropine, damascone, benzyl alcohol, and methyl 2-octynoate. <13> The composition according to any one of <10> to <12>, wherein the mass ratio (A) / (C) of the component (A) to the component (C) is 5 to 2,000. <14> The composition according to any one of <10> to <13>, wherein the mass ratio (A) / (B) of the component (A) to the component (B) is 1 or less. <15> The composition according to any one of <10> to <13>, wherein the mass ratio (A) / (B) of the component (A) to the component (B) is 10 or less. <16> A cosmetic or topical skin preparation comprising the composition according to any one of <10> to <15>. <17> The cosmetic or topical skin preparation according to <16>, wherein the cosmetic or topical skin preparation contains at least an oily agent, and the content of the oily agent is 2 to 20 mass%.
[0135] Hereinafter, the present technology will be described in further detail based on examples, etc. Note that the examples, etc. described below are examples of typical examples, etc. of the present technology, and the scope of the present technology will not be construed as being narrow.
[0136] <Reference Examples 1 to 3> Test for odor change of stearyl glycyrrhetinate with or without niacinamide: Each sample of Reference Examples 1 to 3 in Table 3 was prepared by the following method, and the odor change of stearyl glycyrrhetinate was evaluated and judged according to the evaluation method and criteria shown below. The results are also shown in Table 3.
[0137]
[0138] (Production method) A: Components (1) and (2) were mixed and dissolved. B: Components (3) and (4) were mixed and dissolved. C: After mixing A and B, component (5) was added and mixed to prepare each sample.
[0139] (Evaluation Method 1: Degree of Off-odor of Stearyl Glycyrrhetinate (50°C / 1M)) Regarding the degree of off-odor of stearyl glycyrrhetinate, each sample was stored in a thermostatic chamber at 50°C for one month (1M), and then cooled to room temperature and the fragrance release was evaluated. Using the degree of off-odor confirmed in Reference Example 1 (50°C / 1M) as the standard, six fragrance expert evaluators gave a four-level rating in accordance with the following evaluation criteria, and the average score of all evaluators was calculated and judged. In judging, if the value to the first decimal place of the average score was 5 or less, the decimal points were rounded down, and if it was 6 or more, the decimal points were rounded up. The values shown in Table 3 are as follows:
[0140] [4-level evaluation and judging criteria] (Score and average score): (Evaluation and judging results) 0 points: An oily odor derived from stearyl glycyrrhetinate was detected. -1 point: Compared to 0 point, the oily odor derived from stearyl glycyrrhetinate was slightly stronger. -2 points: Compared to 0 point, the oily odor derived from stearyl glycyrrhetinate was stronger. -3 points: Compared to 0 point, the oily odor derived from stearyl glycyrrhetinate was very stronger.
[0141] As is clear from Table 3, in Reference Example 3 containing stearyl glycyrrhetinate and niacinamide, the offensive odor of stearyl glycyrrhetinate was stronger than in Reference Examples 1 and 2. This result suggests that niacinamide promotes the offensive odor of stearyl glycyrrhetinate. Furthermore, when the niacinamide content was 1% or 2%, the results were similar to those of Reference Example 3.
[0142] Each sample of Examples 1 to 45 and Comparative Examples 1 to 19 in Tables 4 and 5 was prepared by the following method, and the masking effect and matching effect were evaluated according to the evaluation method and criteria shown below. The results are also shown in Tables 4 and 5.
[0143]
[0144]
[0145] (Manufacturing Method) A: Dissolve 1 part by mass of stearyl glycyrrhetinate in 10 parts by mass of dipropylene glycol. B: Dissolve and mix 2 parts by mass of niacinamide in 30 parts by mass of water. C: Mix A and B. D: Adjust the concentration so that the scent of each fragrance component is the same intensity, then add to C and mix. E: Add dipropylene glycol as a correction component to D to make 100 parts by mass, then fill into a glass bottle to obtain each sample. The amount of each fragrance component added shown in Tables 4 and 5 is the mass contained in 100 parts by mass of each sample (composition).
[0146] (Evaluation Method) Six fragrance expert evaluators performed a sensory evaluation of the aroma of each sample at the bottle neck, and verified the masking effect and matching effect of each fragrance component.
[0147] (Evaluation Method 2: Masking Effect (50°C / 1M)) For the masking effect, each sample was stored in a thermostatic chamber at 50°C for one month (1M), and then cooled to room temperature, after which the fragrance release was evaluated. Six fragrance expert evaluators rated the samples on a 5-point scale according to the following evaluation criteria, and the average score of all the evaluators was calculated and judged. The values rounded to the nearest whole number are shown in Tables 4 and 5.
[0148] [5-point rating and judging criteria] (Score and average score): (Rating and judging results) 4 points: Almost no oily odor from stearyl glycyrrhetinate was detected 3 points: A slight oily odor from stearyl glycyrrhetinate was detected 2 points: A slightly strong oily odor from stearyl glycyrrhetinate was detected 1 point: A strong oily odor from stearyl glycyrrhetinate was detected 0 points: A very strong oily odor from stearyl glycyrrhetinate was detected
[0149] (Evaluation Method 3: Matching Effect (50°C / 1M)) The matching effect was examined to see whether the unpleasant odor (oily odor) of stearyl glycyrrhetinate was combined with the fragrance ingredients in Tables 4 and 5 to create a harmonious fragrance. Each sample was stored in a thermostatic chamber at 50°C for one month (1M), and then cooled to room temperature, after which the fragrance release was evaluated. Six fragrance expert evaluators rated the samples on a 5-point scale according to the following evaluation criteria, and the average score of all evaluators was calculated and judged. The values rounded to the nearest whole number are shown in Tables 4 and 5.
[0150] [5-point rating and judging criteria] (Rating and average score): (Rating and judging results) +2 points: The scent blended well with the oily smell from stearyl glycyrrhetinate, creating a pleasant fragrance +1 point: The scent blended well with the oily smell from stearyl glycyrrhetinate, eliminating the unpleasant smell 0 points: There was no change in the unpleasant smell of the oily smell from stearyl glycyrrhetinate -1 point: The unpleasant smell was stronger than the oily smell from stearyl glycyrrhetinate -2 points: The unpleasant smell was worse than the oily smell from stearyl glycyrrhetinate
[0151] From the results in Tables 4 and 5, it can be seen that the contents of anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super, Sandalore, Ambroxan, γ-terpinene, ambrettolide, β-ionone, borneol, and isobutylquinoline in Examples 1 to 45 were significantly higher than those in Examples 1 to 45. Quinoline), Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl AcetateAcetate), α-Terpineol, Geraniol, Geranyl Acetate, Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal, Nerol, Dimethylbenzyl Carbinol, Bacdanol, Methyl Anthranilate It was confirmed that the following compounds have excellent masking and / or matching effects: benzophenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, heliotropine, damascone, benzyl alcohol, and methyl 2-octynoate.On the other hand, allyl caproate, Verdox, phenylacetaldehyde, cis-3-hexenyl acetate, dimethylbenzylcarbinyl acetate, aurantiol, bourgeonal, dihydromycenol, citronellyl acetate, and the like of Comparative Examples 1 to 19 are not included. As for the following aldehydes, γ-decalactone, γ-coumarin, γ-dodecalactone, benzyl salicylate, methyl salicylate, calone, cyclamen aldehyde, hexyl cinnamic aldehyde, acetylcedrene, and anethole, both the masking effect and the matching effect were insufficient.
[0152] Examples 46 to 75, Comparative Examples 20 to 22: Emulsion (oil-in-water type) In order to confirm the effects of cosmetics or topical skin preparations, the emulsions (oil-in-water type) shown in Tables 6 and 7 below were prepared by the production method described below, and the masking effect, matching effect, and lasting effect were evaluated using the evaluation methods and criteria described below. The results are also shown in Tables 6 and 7.
[0153]
[0154] Note 1: CARBOPOL 1382 (manufactured by LUBRIZOL) Note 2: SIMULGEL EG QD (essential content 37.5%, manufactured by SEPPIC) Note 3: CARNATION (manufactured by SONNEBORN) Note 4: KF-96-10CS (manufactured by Shin-Etsu Chemical Co., Ltd.)
[0155] (Manufacturing method) A: Mix and dissolve component (2) and a portion of component (3). B: Heat and mix the remainder of component (3) and components (4) to (6) at 75°C. C: Mix component (1) and components (7) to (15) and heat to 75°C. D: Add C to B and emulsify. E: Cool D to 40°C, then add A and components (16) to (48) and fill into a glass bottle to obtain an emulsion (oil-in-water type).
[0156] (Evaluation Method) Six fragrance expert evaluators performed a sensory evaluation of the scent release of the sample at the bottle opening for masking effect and on the skin for lasting effect, verifying the masking effect, matching effect and lasting effect of each emulsion (oil-in-water type).
[0157] (Evaluation Item 4: Masking Effect (50°C / 1M)) For the masking effect, each sample was stored in a thermostatic chamber at 50°C for one month (1M), and then cooled to room temperature, after which the fragrance release was evaluated. Six fragrance expert evaluators gave a 5-point rating according to the following rating criteria, and the average score of all evaluators was judged according to the following 4-point rating criteria.
[0158] [5-point rating scale] (Rating): (Rating result) 4 points: Almost no oily odor from stearyl glycyrrhetinate was detected 3 points: A slight oily odor from stearyl glycyrrhetinate was detected 2 points: A slightly strong oily odor from stearyl glycyrrhetinate was detected 1 point: A strong oily odor from stearyl glycyrrhetinate was detected 0 points: A very strong oily odor from stearyl glycyrrhetinate was detected
[0159] [4-level evaluation criteria] (Evaluation): (Average score) ◎ (Excellent): Over 3.5 points 〇 (Good): Over 3.0 points, 3.5 points or less △ (Slightly unsatisfactory): Over 2.0 points, 3.0 points or less × (Unsatisfactory): 2.0 points or less
[0160] (Evaluation Method 5: Matching Effect (50°C / 1M)) The matching effect was examined to see whether the unpleasant odor (oily odor) of stearyl glycyrrhetinate was combined with the fragrance component to create a harmonious scent. Each sample was stored in a thermostatic chamber at 50°C for one month (1M), and then cooled to room temperature, after which the fragrance release was evaluated. Six fragrance expert evaluators gave a five-point rating according to the following evaluation criteria, and the average score of all evaluators was judged according to the following four-point rating criteria.
[0161] [5-point rating and judging criteria] (Rating and average score): (Rating and judging results) 4 points: The scent blended well with the oily smell from stearyl glycyrrhetinate, creating a pleasant fragrance 3 points: The scent blended well with the oily smell from stearyl glycyrrhetinate, eliminating the unpleasant smell 2 points: There was no change in the unpleasant smell of the oily smell from stearyl glycyrrhetinate 1 point: The unpleasant smell was stronger than the oily smell from stearyl glycyrrhetinate 0 point: The unpleasant smell was worse than the oily smell from stearyl glycyrrhetinate
[0162] [4-level evaluation criteria] (Evaluation): (Average score) ◎ (Excellent): 3.5 points or more 〇 (Good): 3.0 points or more, less than 3.5 points △ (Slightly unsatisfactory): 2.0 points or more, less than 3.0 points × (Unsatisfactory): Less than 2.0 points
[0163] (Evaluation Method 6: Lasting Effect) For lasting effect, each sample was applied to the skin and the ability to retain the scent on the skin was examined. Six fragrance expert evaluators applied each sample to the skin of their upper arms, and after three hours of absorption, the scent of the target compound on the skin was evaluated on a four-point scale according to the following evaluation criteria, and the average score of all evaluators was evaluated according to the following four-point scale.
[0164] [4-point rating scale] (Rating): (Average rating) 4 points: The fragrance lingers, and the oily smell of stearyl glycyrrhetinate and the oily smell derived from the base were not detected. 3 points: The fragrance lingers, and the oily smell of stearyl glycyrrhetinate and the oily smell derived from the base were barely detected. 2 points: The fragrance lingers, but the oily smell of stearyl glycyrrhetinate and the oily smell derived from the base were detected. 1 point: The fragrance did not linger, and the oily smell of stearyl glycyrrhetinate and the oily smell derived from the base were detected.
[0165] [4-level evaluation criteria] (Evaluation): (Average score) ◎ (Excellent): 3.5 points or more 〇 (Good): 3.0 points or more, less than 3.5 points △ (Slightly unsatisfactory): 2.0 points or more, less than 3.0 points × (Unsatisfactory): Less than 2.0 points
[0166] As is clear from the results in Tables 6 and 7, the emulsions of Examples 46 to 75, which contained compounds with excellent effects in Table 1, were excellent in masking effect, matching effect, and lasting effect. On the other hand, Comparative Example 20, which used phenylacetaldehyde, had insufficient masking effect and lasting effect. Furthermore, Comparative Examples 21 and 22, which used methyl salicylate and Calone, were insufficient in all effects.
[0167] Example 76 Medicated daytime emulsion (oil-in-water type) (Ingredients) (% by weight) 1. Purified water balance 2. Acrylic acid / alkyl methacrylate copolymer (Note 1) 0.25 3. Sodium acryloyldimethyltaurate (Note 2) 0.15 4. Xanthan gum 0.05 5. Polyoxyethylene hydrogenated castor oil (Note 5) 0.1 6. Glycerin fatty acid ester 0.5 7. Dipropylene glycol 5 8. Tripropylene glycol 2 9. 2-ethylhexyl paramethoxycinnamate 3 10. 2,4-bis-[{4-(2-ethylhexyloxy)-2-hydroxy}-phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine (Note 6) 1.5 11. Component Ingredients: Alkyl benzoate (C12-15) 4 12. Liquid paraffin (Note 3) 1 13. Stearyl glycyrrhetinate Component (A) 1 14. Niacinamide Component (B) 5 15. Purified water 15 16. Ethanol 7 17. Linalool Component (C) 0.1 Note 5: Nikkol HCO-60 (molar number 60 E.O., manufactured by Nippon Surfactant Kogyo Co., Ltd.) Note 6: TINOSORB S (manufactured by BASF)
[0168] (Manufacturing method) A: Heat and mix ingredients (1) to (8) at 75°C. B: Mix ingredients (9) to (13) and heat to 75°C. C: Add B to A and emulsify. D: Mix and dissolve ingredients (14) and (15). E: Cool C to 40°C, then add and mix D, ingredients (16) and (17) to obtain a daytime emulsion (oil-in-water type).
[0169] The obtained medicated daytime emulsion (oil-in-water type) had excellent masking effect against the unpleasant odor of stearyl glycyrrhetinate, matching effect, and lasting effect.
[0170] Example 77 Medicinal Cream (Oil-in-Water Type) (Ingredients) (% by mass) 1. Purified water balance 2. Disodium edetate 0.1 3. Erythritol 3 4. 1,3-Butylene glycol 0.15 5. Acrylic acid / alkyl methacrylate copolymer (Note 1) 0.2 6. Hydroxyethyl cellulose 0.15 7. Glycerin 5 8. Polyoxyethylene glycol monostearate (Note 7) 3 9. Behenyl alcohol 2 10. Isostearic acid 1 11. Petrolatum 1.5 12. α-Tocopherol 0.001 12. Squalane 3 13. Stearyl glycyrrhetinate Component (A) 1.5 14. Niacinamide Component (B) 3 15. Purified water 10 16. Ethanol 7 17. γ-Terpinene Component (C) 0.075 Note 7: NIKKOL MYS-40V (manufactured by Nikko Chemicals Co., Ltd.)
[0171] (Manufacturing method) A: Heat and mix ingredients (1) to (7) at 75°C. B: Mix ingredients (8) to (13) and heat to 75°C. C: Add B to A and emulsify. D: Mix and dissolve ingredients (14) and (15). E: Cool C to 40°C, add D, ingredients (16) and (17) and mix to obtain a medicated cream (oil-in-water type).
[0172] The obtained medicated cream (oil-in-water type) had excellent masking effect against the unpleasant odor of stearyl glycyrrhetinate, matching effect, and lasting effect.
[0173] Example 78 Lotion (oil-in-water type) (Ingredients) (% by mass) 1. Purified water balance 2. Disodium edetate 0.1 3. Sodium monohydrogen phosphate 0.1 4. Sodium dihydrogen phosphate 0.1 5. 1,3-butylene glycol 15 6. Polyoxyethylene glycerin (26 E.O.) 5 7. Polyoxyethylene polyoxypropylene decyl tetradecyl ether (Note 8) 0.3 8. N-lauroyl-L-glutamic acid di(phytosteryl 2-octyl dodecyl) (Note 9) 0.05 9. Squalane 0.5 10. Glycyrrhetinic acid stearyl Component (A) 0.5 11. Niacinamide Component (B) 0.5 12. Phenoxyethanol 0.3 13. Ethanol 7 14. Benzyl benzoate Component (C) 0.005 Note 8: NIKKOL SG-DTD620 (Nikko Chemicals Co., Ltd.) Note 9: ELDEW PS-203 (Ajinomoto Co., Inc.)
[0174] (Manufacturing method) A: Mix components (1) to (6) and component (11). B: Mix components (7) to (10). C: Add B to A and emulsify. D: Add components (12) to (14) to C and mix to obtain a lotion (oil-in-water type).
[0175] The obtained lotion (oil-in-water type) had excellent masking effect against the unpleasant odor of stearyl glycyrrhetinate, matching effect, and lasting effect.
[0176] Example 79 Pharmaceutical Cream (Oil-in-Water Type) (Ingredients) (% by mass) 1. Purified water balance 2. Disodium edetate 0.1 3. Dipropylene glycol 5 4. 1,3-butylene glycol 5 5. Hydroxypropyl methylcellulose 0.2 6. Polyoxyethylene sorbitan monooleate (20 E.O.) 0.7 7. Methyl parahydroxybenzoate 0.1 8. Glycerin fatty acid ester 3 9. Behenyl alcohol 1.5 10. Heparinoid 0.3 11. White petrolatum 1.5 12. Beeswax 1 12. Squalane 3 13. Stearyl glycyrrhetinate Component (A) 1.0 14. Niacinamide Component (B) 2.5 15. Purified water 10 16. Ethanol 5 17. Geranyl acetate Component (C) 0.1
[0177] (Manufacturing method) A: Heat and mix ingredients (1) to (5) at 75°C. B: Mix ingredients (6) to (13) and heat to 75°C. C: Add B to A and emulsify. D: Mix and dissolve ingredients (14) and (15). E: Cool C to 40°C, add D, ingredients (16) and (17) and mix to obtain a medicated cream (oil-in-water type).
[0178] The obtained medicinal cream (oil-in-water type) had excellent masking effect against the unpleasant odor of stearyl glycyrrhetinate, matching effect, and lasting effect.
[0179] <Reference Examples 4 to 6> Test for odor change of stearyl glycyrrhetinate with or without tranexamic acid: Each sample of Reference Examples 4 to 6 in Table 8 was prepared in the same manner as in Reference Examples 1 to 3, and the odor change of stearyl glycyrrhetinate was evaluated and judged using the same evaluation method and criteria as in Reference Examples 1 to 3. The results are also shown in Table 8.
[0180]
[0181] As is clear from Table 8, in Reference Example 6, which contained stearyl glycyrrhetinate and tranexamic acid, the offensive odor of stearyl glycyrrhetinate was stronger than in Reference Examples 4 and 5. This result suggests that tranexamic acid promotes the offensive odor of stearyl glycyrrhetinate. Note that when the tranexamic acid content was 5% or 10%, the results were similar to those of Reference Example 6.
[0182] Examples 80 to 119, Comparative Examples 23 to 44 Samples of Examples 80 to 119 and Comparative Examples 23 to 44 in Tables 9 and 10 were prepared by the following methods. The masking effect and matching effect were evaluated and judged using the same evaluation methods and criteria as in Examples 1 to 45 and Comparative Examples 1 to 19, and the results are also shown in Tables 9 and 10.
[0183]
[0184]
[0185] (Manufacturing Method) A: Dissolve 1 part by mass of stearyl glycyrrhetinate in 10 parts by mass of dipropylene glycol. B: Dissolve and mix 2 parts by mass of tranexamic acid in 30 parts by mass of water. C: Mix A and B. D: Adjust the concentration so that the scent of each fragrance component is the same intensity, then add to C and mix. E: Add dipropylene glycol as a correction component to D to make 100 parts by mass, then fill into a glass bottle to obtain each sample. The amount of each fragrance component added shown in Tables 9 and 10 is the mass contained in 100 parts by mass of each sample (composition).
[0186] From the results in Tables 9 and 10, it can be seen that the anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super, Sandalore, Ambroxan, γ-terpinene, ambrettolide, β-ionone, borneol, and isobutylquinoline of Examples 80 to 119 are Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Benzyl Benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde Dimethyl Acetal It was confirmed that the following compounds have excellent masking and / or matching effects: Benzyl acetate, Benzyl acetal, Nerol, Dimethyl benzyl carbinol, Bacdanol, Methyl anthranilate, Muscenone, Benzyl acetate, Phenylethyl alcohol, Phenylethyl acetate, and Heliotropine.On the other hand, geranyl acetate and anethole in Comparative Examples 23 and 24 had insufficient masking effects, and geraniol, allyl caproate, Verdox, phenylacetaldehyde, cis-3-hexenyl acetate, and dimethyl benzyl carbinyl acetate in Comparative Examples 25 to 44 had insufficient masking effects. Acetate), Aurantiol, Bourgeonal, Dihydromycenol, Citronellyl Acetate, γ-Decalactone, Damascone, Coumarin, γ-Dodecalactone, Benzyl Salicylate, Methyl Salicylate, Calone, Cyclamen Aldehyde, Hexyl Cinnamic Aldehyde As for acetyl cedrene, both the masking effect and the matching effect were insufficient.
[0187] Examples 120 to 147, Comparative Examples 45 to 47: Emulsions (oil-in-water type) To confirm the effects as cosmetics or topical skin preparations, the emulsions (oil-in-water type) shown in Tables 11 and 12 were prepared by the following production method. The masking effect, matching effect, and lasting effect were evaluated using the same evaluation methods and criteria as in Examples 46 to 75 and Comparative Examples 20 to 22, and the results are also shown in Tables 11 and 12.
[0188]
[0189]
[0190] (Manufacturing method) A: Mix and dissolve component (2) and a portion of component (3). B: Heat and mix the remainder of component (3) and components (4) to (6) at 75°C. C: Mix component (1) and components (7) to (14) and heat to 75°C. D: Add C to B and emulsify. E: Cool D to 40°C, then add A and components (15) to (45) and fill into a glass bottle to obtain an emulsion (oil-in-water type).
[0191] As is clear from the results in Tables 11 and 12, the emulsions of Examples 120 to 147, which contained compounds with excellent effects in Table 2, were excellent in masking effect, matching effect, and lasting effect. On the other hand, Comparative Example 45, which used phenylacetaldehyde, had insufficient masking effect and matching effect. Furthermore, Comparative Example 46, which used methyl salicylate, and Comparative Example 47, which used Calone, were insufficient in all effects.
[0192] Example 148 Beauty Essence (oil-in-water type) (Ingredients) (% by mass) 1. Purified water balance 2. Acrylic acid / alkyl methacrylate copolymer (Note 1) 0.2 3. Carboxyvinyl polymer (Note 10) 0.2 4. Xanthan gum 0.1 5. Polyoxyethylene hydrogenated castor oil (Note 11) 0.1 6. Cholesterol 0.001 7. 2-ethylhexyl paramethoxycinnamate 5 8. N-stearoyldihydrosphingosine 0.01 9. N-stearoylphytosphingosine 0.01 10. 2-ethylhexyl hexanoate 3 11. Behenyl alcohol 0.3 12. Stearyl glycyrrhetinate Component (A) 0.5 13. Tranexamic acid Component (B) 3 14. 15. Sodium pyrosulfite 0.01 16. Purified water 10 17. Ethanol 5 18. Linalyl acetate Component (C) 0.05 Note 10: CARBOPOL 980 (manufactured by LUBRIZOL) Note 11: Nikkol HCO-80 (mol number 80 E.O. manufactured by Nippon Surfactant Kogyo Co., Ltd.)
[0193] (Manufacturing Method) A: Heat and mix components (1) to (4) at 75°C. B: Mix components (5) to (12) and heat to 100°C. C: Add B to A and emulsify. D: Mix and dissolve components (13) to (15). E: Cool C to 40°C, then add D, components (16) and (17) and mix to obtain a cosmetic serum (oil-in-water type).
[0194] The obtained beauty serum (oil-in-water type) had excellent masking effect against the unpleasant odor of stearyl glycyrrhetinate, matching effect, and lasting effect.
[0195] Example 149 Medicinal daytime emulsion (oil-in-water type) (Ingredients) (% by weight) 1. Purified water balance 2. Acrylic acid / alkyl methacrylate copolymer (Note 1) 0.2 3. Sodium acryloyldimethyltaurate (Note 2) 0.2 4. Xanthan gum 0.1 5. Polyoxyethylene hydrogenated castor oil (Note 5) 0.1 6. Behenyl alcohol 0.7 7. Dipropylene glycol 3 8. Glycerin 3 9. Tripropylene glycol 1 10. Sodium metabisulfite 0.01 11. 12. 2,4-bis-[{4-(2-ethylhexyloxy)-2-hydroxy}-phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine (Note 6) 1.5 13. Dipropylene glycol 5 14. Liquid paraffin (Note 3) 1 15. Stearyl glycyrrhetinate Component (A) 1 16. Tranexamic acid Component (B) 2.5 17. Purified water 15 18. Ethanol 8 19. Citronellol Component (C) 0.1
[0196] (Manufacturing method) A: Heat and mix ingredients (1) to (10) at 75°C. B: Mix ingredients (11) to (15) and heat to 75°C. C: Add B to A and emulsify. D: Mix and dissolve ingredients (16) and (17). E: Cool C to 40°C, then add D, ingredients (18) and (19) and mix to obtain a medicated daytime emulsion (oil-in-water type).
[0197] The obtained medicated daytime emulsion (oil-in-water type) had excellent masking effect against the unpleasant odor of stearyl glycyrrhetinate, matching effect, and lasting effect.
[0198] Example 150 Primer (water-in-oil type) (Components) (% by mass) 1. Purified water balance 2. Disodium edetate 0.1 3. Sodium monohydrogen phosphate 0.1 4. Sodium dihydrogen phosphate 0.1 5. Sodium chloride 0.5 6. Sodium metabisulfite 0.02 7. Butylene glycol 1 8. Tranexamic acid Component (B) 4 9. Titanium oxide 1 10. Zinc oxide 3 11. Dimethyl distearyl ammonium hectorite 0.3 12. Zinc oxide 3 13. 2-ethylhexyl paramethoxycinnamate 5 14. Isotridecyl isononanoate 3 15. Methylpolysiloxane 2 16. Methylphenylpolysiloxane 1 17. 18. PEG-9 polydimethylsiloxyethyl dimethicone 3 19. Sorbitan sesquioleate 0.5 20. Sorbitan sesquiisostearate 0.5 21. Stearyl glycyrrhetinate (Component (A)) 1.5 22. Ethanol 5 23. β-ionone (Component (C)) 0.015
[0199] (Manufacturing method) A: Mix components (1) to (8). B: Mix components (9) to (21) in a super mixer. C: Add A to B and emulsify. D: Add components (22) and (23) to C and mix to obtain a base (water-in-oil type).
[0200] The obtained base (water-in-oil type) had excellent masking effect against the unpleasant odor of stearyl glycyrrhetinate, matching effect, and lasting effect.
[0201] Example 151 Medicinal hand cream (oil-in-water type) (Ingredients) (% by mass) 1. Purified water balance 2. Disodium edetate 0.1 3. Acrylic acid / alkyl methacrylate copolymer (Note 1) 0.2 4. Carboxyvinyl polymer (Note 10) 0.5 5. 1,3-butylene glycol 3 6. Sodium metabisulfite 0.05 7. Glyceryl monostearate 2 8. Polyoxyethylene glycol monostearate (Note 7) 2 9. Behenyl alcohol 2 10. Astaxanthin 0.001 11. Petrolatum 1.5 12. α-tocopherol 0.001 13. Tri(caprylic / capric acid)glyceryl 3 14. Stearyl glycyrrhetinate Component (A) 2 15. Tranexamic acid component (B) 3.5 16. Purified water 10 17. Ethanol 7 18. Citronellol component (C) 0.2
[0202] (Manufacturing method) A: Heat and mix ingredients (1) to (6) at 75°C. B: Mix ingredients (7) to (14) and heat to 75°C. C: Add B to A and emulsify. D: Mix and dissolve ingredients (15) and (16). E: Cool C to 40°C, add D, ingredients (17) and (18) and mix to obtain a medicated hand cream (oil-in-water type).
[0203] The obtained medicated hand cream (oil-in-water type) had excellent masking effect against the unpleasant odor of stearyl glycyrrhetinate, matching effect, and lasting effect.
[0204] Example 152 Pharmaceutical cream (oil-in-water type) (Ingredients) (% by mass) 1. Purified water balance 2. Disodium edetate 0.1 3. Dipropylene glycol 3 4. 1,3-butylene glycol 7 5. Heparinoid 0.4 6. Sodium metabisulfite 0.03 7. Hydroxyethyl cellulose 0.5 8. Polyoxyethylene hydrogenated castor oil (Note 5) 0.8 9. Methyl parahydroxybenzoate 0.1 10. Glycerin fatty acid ester 3 11. Squalane 2 12. White petrolatum 1.2 13. Microcrystalline wax 0.8 14. Light liquid paraffin 4 15. Stearyl glycyrrhetinate Component (A) 1 16. Tranexamic acid Component (B) 3 17. Purified water 10 18. Ethanol 5 19. Linalyl acetate Component (C) 0.1
[0205] (Manufacturing method) A: Heat and mix ingredients (1) to (7) at 75°C. B: Mix ingredients (8) to (15) and heat to 75°C. C: Add B to A and emulsify. D: Mix and dissolve ingredients (16) and (17). E: Cool C to 40°C, add D, ingredients (18) and (19) and mix to obtain a pharmaceutical cream (oil-in-water type).
[0206] The obtained medicinal cream (oil-in-water type) had excellent masking effect against the unpleasant odor of stearyl glycyrrhetinate, matching effect, and lasting effect.
Claims
1. A method for improving the odor of a composition containing stearyl glycyrrhetinate and niacinamide or tranexamic acid, comprising adding anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), glycyrrhetinic acid, niacinamide, tranexamic acid, ... Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutyl Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Benzyl Benzoate Benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol At least one selected from the group consisting of alcohol, phenylethyl acetate, and heliotropine.A method of improving odors by adding 2. A method for improving the odor of a composition containing stearyl glycyrrhetinate and tranexamic acid, comprising adding anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexanol, linalool, cedryl acetate, Iso E Super (Iso E Super), glycyrrhetinic acid, ... Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutyl Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Benzyl Benzoate Benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol A method for improving an odor by adding at least one selected from the group consisting of alcohol, phenylethyl acetate, and heliotropine.
3. A method for improving the odor of a composition containing stearyl glycyrrhetinate and niacinamide, comprising adding anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexanol, linalool, cedryl acetate, Iso E Super (Iso E Super), glycyrrhetinic acid stearyl, niacinamide, ... Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutyl Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Geraniol, Geranyl Acetate acetate, benzyl benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate acetate), phenylethyl alcohol, phenylethyl acetate,A method for improving an odor by adding at least one selected from the group consisting of heliotropine, damascone, benzyl alcohol, and methyl 2-octynoate.
4. An odor improving agent for improving the odor of a composition containing stearyl glycyrrhetinate and niacinamide or tranexamic acid, comprising anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super, Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutyl Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Benzyl Benzoate Benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol At least one selected from the group consisting of alcohol, phenylethyl acetate, and heliotropine.An odor improving agent containing as an active ingredient.
5. An odor improving agent for improving the odor of a composition containing stearyl glycyrrhetinate and tranexamic acid, comprising an anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexanol, linalool, cedryl acetate, Iso E Super, Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutyl Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Benzyl Benzoate Benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol The odor improving agent contains at least one active ingredient selected from the group consisting of alcohol, phenylethyl acetate, and heliotropine.
6. An odor improving agent for improving the odor of a composition containing stearyl glycyrrhetinate and niacinamide, comprising anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexanol, linalool, cedryl acetate, Iso E Super, Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutyl Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Geraniol, Geranyl Acetate acetate, benzyl benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate acetate), phenylethyl alcohol, phenylethyl acetate, heliotropine,An odor improving agent comprising at least one active ingredient selected from the group consisting of damascone, benzyl alcohol, and methyl 2-octynoate.
7. The following ingredients (A) to (C): (A) stearyl glycyrrhetinate (B) niacinamide or tranexamic acid (C) anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexanol, linalool, cedryl acetate, Iso E Super (Iso E Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutyl Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Benzyl Benzoate Benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol At least one selected from the group consisting of alcohol, phenylethyl acetate, and heliotropine.The composition for improving an odor containing stearyl glycyrrhetinate and niacinamide or tranexamic acid contains the above formula:
8. The following components (A) to (C):(A) Stearyl glycyrrhetinate (B) Tranexamic acid (C) Anise alcohol, Farnesol, Eugenol, Citronellol, α-Pinene, 1-Hexanol, Linalool, Cedryl acetate, Iso E Super, Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutylquinoline Quinoline, Citral, Guaiacol, Patchouli alcohol, Cedrol, Ethyl vanillin, Maltol, Linalyl acetate, α-Terpineol, Benzyl benzoate, Damascenone, Anisaldehyde, Benzaldehyde, Magnolan, Mayol, Phenylacetaldehyde dimethyl acetal A composition for improving an odor of stearyl glycyrrhetinate and tranexamic acid, containing at least one member selected from the group consisting of dimethyl benzyl carbinol, acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, and heliotropine.
9. The following ingredients (A) to (C): (A) stearyl glycyrrhetinate (B) niacinamide (C) anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexanol, linalool, cedryl acetate, Iso E Super (Iso E Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutyl Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Geraniol, Geranyl Acetate acetate, benzyl benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate acetate), phenylethyl alcohol, phenylethyl acetate, heliotropine,A composition for improving odors, comprising stearyl glycyrrhetinate and niacinamide, and containing at least one member selected from the group consisting of damascone, benzyl alcohol, and methyl 2-octynoate.
10. The following ingredients (A) to (C): (A) stearyl glycyrrhetinate (B) niacinamide or tranexamic acid (C) anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super (Iso E Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutyl Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Benzyl Benzoate Benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol A composition comprising at least one selected from the group consisting of alcohol, phenylethyl acetate, and heliotropine.
11. The following ingredients (A) to (C): (A) stearyl glycyrrhetinate (B) tranexamic acid (C) anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutyl Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Benzyl Benzoate Benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate, phenylethyl alcohol A composition comprising at least one selected from the group consisting of alcohol, phenylethyl acetate, and heliotropine.
12. The following ingredients (A) to (C): (A) stearyl glycyrrhetinate (B) niacinamide (C) anise alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexen-1-ol, linalool, cedryl acetate, Iso E Super Super), Sandalore, Ambroxan, γ-Terpinene, Ambrettolide, β-Ionone, Borneol, Isobutyl Quinoline, Citral, Guaiacol, Patchouli Alcohol, Cedrol, Ethyl Vanillin, Maltol, Linalyl Acetate, α-Terpineol, Geraniol, Geranyl Acetate acetate, benzyl benzoate, damascenone, anisaldehyde, benzaldehyde, magnolan, mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, bacdanol, methyl anthranilate, muscenone, benzyl acetate acetate), phenylethyl alcohol, phenylethyl acetate, heliotropine,A composition comprising at least one member selected from the group consisting of damascone, benzyl alcohol, and methyl 2-octynoate.
13. The composition according to any one of claims 10 to 12, wherein the mass ratio (A) / (C) of the component (A) to the component (C) is 5 to 2,000.
14. The composition according to claim 11, wherein the mass ratio (A) / (B) of the component (A) to the component (B) is 1 or less.
15. The composition according to claim 12, wherein the mass ratio (A) / (B) of the component (A) to the component (B) is 10 or less.
16. A cosmetic or topical skin preparation comprising the composition according to any one of claims 10 to 12.
17. The cosmetic or topical skin preparation according to claim 16, which contains at least an oily agent, and the content of the oily agent is 2 to 20 mass %.
Citation Information
Patent Citations
Antioxidative perfume composition and skin care preparation containing the same
JP2007291031A
Solubilized cosmetic
JP2015174838A
Skin external composition
JP2019019077A
Aqueous cosmetic preparation
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Composition
WO2024135645A1
Cited By
Composition
JPWO2024135645A1