Chamber system

Abstract

The present invention provides a chamber system which is useful for studying the effects of contaminants, particularly contaminants in the form of aerosols, on living organisms.

Description

Chamber system

[0001] The present application relates to a chamber system, and more specifically, to a chamber system capable of analyzing the biological association between aerosols and living organisms.

[0002] In modern society, where technology is highly developed, interest in environmental protection and ecosystem restoration is increasing.

[0003] To protect the environment and restore the ecosystem, active research is being conducted on the effects of pollutants on living organisms, but useful equipment for such research has not yet been developed.

[0004] The present application aims to solve the problem of providing a chamber system useful for studying the effects of pollutants, particularly aerosol-type pollutants, on living organisms.

[0005] In order to solve the above problem, a chamber system is provided, which includes a chamber having a receiving space for receiving a living organism, a supply unit for supplying sample aerosol to the living organism in the receiving space, a monitoring unit for monitoring a change in motion or image of the living organism before and after supplying the sample aerosol, and an analysis unit for analyzing a biological correlation between the sample aerosol and the living organism based on the monitoring result.

[0006] Additionally, the sample aerosol may include at least one of solid particles, liquid particles, and composite particles comprising a combination of liquid particles and solid particles.

[0007] Additionally, the solid particles may include metallic or non-metallic particles.

[0008] Additionally, the liquid particles may include organic compounds, inorganic compounds, or mixtures thereof.

[0009] Additionally, the supply unit may include a manufacturing unit for manufacturing a sample aerosol.

[0010] In addition, the above-mentioned receiving space may further include a pollutant supply unit configured to supply gaseous pollutants to the organisms.

[0011] Additionally, the gaseous pollutants may include one or more selected from the group consisting of carbon monoxide, carbon dioxide, formaldehyde, nitrogen dioxide, sulfur dioxide, hydrogen sulfide, volatile organic compounds, aromatic hydrocarbons, methylene chloride, ethylene chloride, ammonia, ozone, naphthalene, and radon.

[0012] Additionally, it may include a sensor for measuring the air quality of the receiving space.

[0013] Additionally, the chamber may include a ventilation fan that supplies outside air to the receiving space and exhausts inside air of the receiving space to the outside, and a control unit that controls the operation of at least one of the ventilation fan, the supply unit, and the contaminant supply unit based on the measurement results of the sensor.

[0014] In addition, the control unit may include a first mode for turning on the operation of at least one of the ventilation fan, the supply unit, and the pollutant supply unit when the measurement result of the sensor exceeds a set reference value, and a second mode for turning off the operation of at least one of the ventilation fan, the supply unit, and the pollutant supply unit when the measurement result of the sensor does not exceed a set reference value.

[0015] Additionally, the chamber may include a collection unit for collecting a sample candidate comprising at least one of a sample aerosol and a gaseous contaminant supplied to the receiving space.

[0016] The chamber system according to the present application has the advantage of being useful for studying the effects of aerosol-type pollutants on living organisms.

[0017] FIG. 1 is a configuration diagram of a chamber system according to one embodiment of the present application.

[0018] Figures 2 and 3 are drawings to aid in understanding of a chamber system capable of studying the effects of sample aerosols on animals.

[0019] Figures 4 and 5 are drawings to help understand the chamber system that can study the effects of sample aerosols on plants.

[0020] The present application relates to a chamber system.

[0021] The chamber system according to the present application may be a device that can be used for research on the effects of contaminants on living organisms.

[0022] FIG. 1 is a configuration diagram of a chamber system according to one embodiment of the present application.

[0023] The chamber system according to the present application includes a chamber (100), a supply unit (200), a monitoring unit (300), and an analysis unit (400).

[0024] The chamber (100) has a space for accommodating a living organism. The types of living organisms are not limited to bacteria, insects, animals, plants, etc., and may also include human skin tissue or organ tissue that can respond to external stimuli. The chamber (100) may be designed to an appropriate size considering the size of the living organism.

[0025] Additionally, the chamber (100) may be made of a material with low reactivity with contaminants or coated with the material. The material may be, for example, Teflon.

[0026] The chamber (100) may include a heater for supplying heat to the receiving space, a dehumidifying device for removing moisture from the receiving space, and a temperature and humidity control unit for controlling the operation of the heater and dehumidifying device to control the temperature and humidity of the receiving space. In addition, the chamber (100) may additionally include a lighting device.

[0027] Additionally, the chamber (100) may be equipped with an alarm device that detects situations such as excessive temperature changes or gas leaks and notifies the outside.

[0028] Additionally, the chamber (100) may be made of a transparent material or may have a transparent window installed to facilitate observation of the receiving space from the outside.

[0029] The supply unit (200) supplies sample aerosol to the organism within the receiving space. The supply unit (200) is a sample aerosol supply unit. In the present invention, the sample aerosol refers to solid particles, liquid particles (also called droplets), or composite particles formed by combining liquid particles and solid particles suspended in the air.

[0030] In the present invention, a sample aerosol may mean an aerosol generated in an everyday environment (e.g., an aerosol generated during cooking) or an aerosol generated in a specific environment (e.g., an aerosol generated during welding) or one manufactured by simulating the same.

[0031] The above supply unit (200) can supply sample aerosol to living organisms in the receiving space through a mechanical atomizer, nebulizer, impinger, mechanical spray, ultrasonic spray, electrospray, or gas injection dust dispenser.

[0032] The above supply unit (200) may include a supply amount control unit that controls the supply amount of sample aerosol. The supply amount control unit can control the concentration of sample aerosol within the receiving space by controlling the supply amount of sample aerosol.

[0033] Additionally, the supply unit (200) can control the supply frequency of the sample aerosol. For example, the supply unit (200) can supply the sample aerosol a fixed number of times over a fixed period of time. By controlling the supply frequency of the sample aerosol, the analysis unit (400) can help identify the functional or adverse health effects of an organism due to acute, subchronic, or chronic exposure to the sample aerosol.

[0034] The monitoring unit (300) monitors changes in motion or image of a living organism before and after supplying a sample aerosol. For example, the monitoring unit (300) may include a camera that captures images of the living organism and a storage unit that stores images captured by the camera. The camera may use various types of cameras, such as a high-resolution camera or an infrared camera. In particular, an infrared camera can detect changes in the body temperature of a living organism.

[0035] In addition, the monitoring unit (300) includes various markers that detect changes in movement, heart rate, respiration rate, body temperature, etc. of a living organism, and the markers may be attached to the living organism.

[0036] The above monitoring unit (300) can monitor changes in the behavior of a living organism before and after exposure to a sample aerosol, or monitor changes in the body temperature of the living organism or changes in the shape or color of a surface area.

[0037] For example, the monitoring unit (300) can monitor changes in the behavior of an organism using a heat map. Specifically, the monitoring unit (300) can convert a chamber into a 2D or 3D map to create a virtual map, and display the movement path of the organism, the time spent at a specific location, etc. on the created virtual map to monitor changes in the behavior of the organism.

[0038] For example, the monitoring unit (300) can be linked to a cloud-based system, allowing users to remotely access and analyze data. This allows users to monitor the progress of the experiment anytime, anywhere and take immediate action if necessary.

[0039] The above analysis unit (400) analyzes the biological correlation between the sample aerosol and the organism based on the monitoring results. The biological correlation may include various analysis targets, such as physiological responses, genetic changes, and biochemical responses.

[0040] The above analysis unit (400) can analyze what pattern the motion change or image change of a living organism has before and after exposure to a sample aerosol, and can precisely analyze the influence of the particle size, type, chemical properties, exposure time, etc. of the sample aerosol on the behavior, growth, health status, etc. of the living organism through pattern analysis.

[0041] Additionally, the analysis unit (400) can analyze functional or adverse health effects according to the sample aerosol.

[0042] For example, the above analysis unit (400) can analyze acute, subchronic, and chronic types of diseases of a living organism due to exposure to a sample aerosol. Examples of the diseases include respiratory diseases, cardiovascular diseases, cerebrovascular diseases, pulmonary diseases, endocrine diseases, blood diseases, liver diseases, obesity diseases, mental diseases, urinary diseases, reproductive diseases, neurological diseases, autoimmune diseases, genetic diseases, skin diseases, eye diseases, periodontal diseases, and behavioral diseases.

[0043] The above analysis unit (400) can perform analysis by applying a deep-learning-based learning algorithm.

[0044] In addition, the above analysis unit (400) can analyze the effects on the behavior, growth, health status, etc. of an organism depending on the concentration of the sample aerosol.

[0045] In addition, the above analysis unit (400) can analyze the effect on the behavior, growth, health status, etc. of an organism according to the supply frequency of the sample aerosol.

[0046] In one example, the sample aerosol may include at least one of solid particles, liquid particles, and composite particles comprising a combination of liquid particles and solid particles. The sample aerosol may have the particles suspended in the air.

[0047] The solid particles may include, for example, metal particles or non-metal particles. Examples of the metal particles include iron particles, aluminum particles, lead particles, etc., and examples of the non-metal particles include silica particles, latex particles, carbon-based particles, etc.

[0048] The liquid particles may include, for example, organic compounds, inorganic compounds, or mixtures thereof. Examples of organic compounds include alcohols, ketones, and esters, while examples of inorganic compounds include sodium hydroxide, potassium hydroxide, and sulfuric acid.

[0049] For example, the liquid particles may include various natural substances found in daily life or their imitation substances. Here, the imitation substance refers to a substance artificially manufactured to resemble a natural substance. For example, the liquid particles may include oil droplets such as oil mist generated during cooking, volatile organic compound droplets formed by condensation after evaporation of volatile organic compounds, and water-soluble droplets formed by condensation of water-soluble substances such as nitrogen oxides and sulfur oxides dissolved in moisture in the air.

[0050] Additionally, the composite particles may have a core-shell structure in which liquid particles surround solid particles.

[0051] In one specific example, the supply unit (200) may include a first supply unit (210) for supplying a first sample aerosol including solid particles, a second supply unit (220) for supplying a second sample aerosol including liquid particles, and a third supply unit (230) for supplying a third sample aerosol including composite particles.

[0052] In one example, the supply unit (200) may include a manufacturing unit for manufacturing a sample aerosol. The manufacturing unit may be a separate device from the supply unit (200), or may be a device integrally combined with the supply unit (200). When the manufacturing unit and the supply unit (200) are integrally combined, a sample aerosol can be manufactured in a single device and then supplied to the receiving space using a living organism.

[0053] The first supply unit (210) may include a first production unit (210) for producing a first sample aerosol including solid particles, the second supply unit (220) may include a second production unit (220) for producing a second sample aerosol including liquid particles, and the third supply unit (230) may include a third production unit (230) for producing a third sample aerosol including composite particles. The first production unit (210) may include a spark ejection device, the second production unit (220) may include an atomizer or an atomizer, and the third production unit (230) may include a spark ejection device, an atomizer, or an atomizer.

[0054] In the present invention, the first to third supply units and the first to third manufacturing units are understood as equipment that is integrally combined and are represented by the same symbol, but are not limited thereto, and the first to third supply units and the first to third manufacturing units may be different equipment that are each separate from each other.

[0055] In addition, the first to third manufacturing units (210, 220, 230) may include a gas supply device that supplies a gas such as air, and the particles manufactured in the first to third manufacturing units (210, 220, 230) may be mixed with a gas supplied from the gas supply device to be manufactured in the form of an aerosol.

[0056] In the third manufacturing unit (230), solid particles manufactured by spark blasting can be combined with liquid particles generated through an atomizer or sprayer to form composite particles.

[0057] In addition, the third manufacturing unit (230) may include a photoirradiation device. The photoirradiation device may irradiate light to the composite particles, and through the photoirradiation, the bonding force between the components of the composite particles may be increased and the stiffening of the composite particles may be induced.

[0058] The above spark discharging device can produce metal nanoparticles from a metal electrode by spark discharge. Here, "spark discharge" means a high-frequency discharge method performed in a kV-mA mode at atmospheric pressure. In addition, the term "nano" in the present application may mean a size in nanometers (nm), for example, 1 to 1,000 nm, but is not limited thereto. In addition, the term "nanoparticle" in the present application may mean a particle having an average diameter in nanometers (nm), for example, 1 to 1,000 nm, but is not limited thereto.

[0059] The above spark generating device may include, for example, a discharge unit, an AC power supply unit, and an AC power control unit.

[0060] The above discharge unit is a unit that generates metal nanoparticles by spark discharge, and the discharge unit includes a pair of metal electrodes spaced apart from each other at a predetermined interval, and the pair of metal electrodes are spaced apart from each other to form a gap. For example, in the discharge unit, metal nanoparticles can be generated by a high temperature locally generated between the metal electrodes by spark discharge.

[0061] The metal material constituting the metal electrode is not particularly limited as long as it is a conductive material, and for example, the metal electrode may include one or more selected from the group consisting of aluminum, antimony, tin, bismuth, carbon nanotubes, cerium, copper, cobalt, fullerene, POSS (Polyhedral Oligomeric Silsesquioxane), graphene, iron, magnesium, manganese, lead, gold, silver, nickel, silicon, titanium, yttrium, zinc, and zirconium.

[0062] In addition, the metal nanoparticles generated from the metal electrodes may be transformed into oxides by reacting with oxygen gas passing between the metal electrodes. For example, the types of metal nanoparticles generated from between the metal electrodes may include at least one selected from the group consisting of aluminum, antimony, tin, bismuth, carbon nanotubes, cerium, copper, cobalt, fullerene, POSS (Polyhedral Oligomeric Silsesquioxane), graphene, iron, magnesium, manganese, lead, gold, silver, nickel, silicon, titanium, yttrium, zinc, zirconium, and oxides thereof.

[0063] The AC power supply may be a part that applies AC power or electric power to the metal electrode. The AC power supply may apply AC power as a pulse signal to the metal electrode. When applying AC power as described above, unlike a DC power supply, there is an advantage in that a separate circuit for frequency variation is not required, allowing for easy frequency control.

[0064] The frequency and voltage of the AC power generated from the AC power supply unit can be controlled by the AC power control unit. The AC power control unit controls the frequency and voltage of the AC power applied to the metal electrode within a specific range, thereby supplying a constant AC current to the metal electrode.

[0065] In the above AC power control unit, the frequency of the AC power can be controlled to 20 kHz or more, for example, 30 kHz or more or 40 kHz or more, and the upper limit of the frequency is not particularly limited, but can be, for example, 1 MHz or less.

[0066] In addition, the voltage of the AC power in the AC power control unit can be controlled to 2.2 to 5.0 kV, for example, 2.5 kV to 4.5 kV, 2.2 kV to 3.5 kV, 3.0 kV to 4.0 kV, or 3.5 kV to 5.0 kV, but is not limited thereto.

[0067] By controlling the frequency and voltage of the AC power applied to the metal electrode within the aforementioned range, even when metal nanoparticles are manufactured using a spark discharge rather than an arc discharge method, the particle size of the metal nanoparticles generated from the metal electrode can be maintained in the nanometer unit while the amount of metal nanoparticles manufactured per hour can be maximized.

[0068] Additionally, the spark ignition device may include a direct current power supply instead of an alternating current power supply.

[0069] In one example, the first to third supply units (210, 220, 230) (or the first to third manufacturing units) may be connected in series or in parallel with each other.

[0070] For example, in the case of serial connection, the sample aerosols produced in the first to third supply units (210, 220, 230) (or the first to third manufacturing units) can be applied to complex in a layer-by-layer form, and in the case of parallel connection, the sample aerosols produced in each supply unit can be applied to randomly aggregate.

[0071] The chamber system according to the present invention can produce a sample aerosol by simulating an aerosol generated in an everyday environment (e.g., an aerosol generated during cooking) or a specific environment (e.g., an aerosol generated during welding) through the first to third production sections (210, 220, 230).

[0072] In one example, the apparatus may further include a contaminant supply unit (500) configured to supply gaseous contaminants to living organisms within the receiving space.

[0073] The above analysis unit (400) can analyze the effects of gaseous pollutants on the behavior, growth, health, etc. of a living organism from changes in motion or image of the living organism before and after supplying the gaseous pollutants. In addition, the analysis unit (400) can analyze the effects of the sample aerosol and the gaseous pollutants on the behavior, growth, health, etc. of a living organism when the sample aerosol and the gaseous pollutants are supplied together.

[0074] For example, the gaseous pollutant may include, but is not limited to, one or more selected from the group consisting of carbon dioxide, formaldehyde, nitrogen dioxide, sulfur dioxide, hydrogen sulfide, volatile organic compounds, aromatic hydrocarbons, methylene chloride, ethylene chloride, ammonia, ozone, naphthalene, and radon, and may include various known gaseous pollutants.

[0075] In particular, carbon monoxide and nitrogen dioxide are suitable for studying air pollution in cities with high traffic volumes, while formaldehyde and volatile organic compounds are primarily used for studying indoor air quality. Radon can be used for studying human exposure to radon released from building materials in indoor air quality and from soil and other sources in air pollution.

[0076] Additionally, the present invention may include a data storage unit that stores monitoring and analysis results as data. Through the data stored in the data storage unit, a user can understand the reactions of organisms exposed to sample aerosols and immediately take follow-up measures.

[0077] In one specific example, the apparatus may further include a bioaerosol supply unit configured to supply bioaerosol to living organisms within the receiving space. The bioaerosol refers to viruses, bacteria, mold, pollen, etc. floating in the air.

[0078] The above bioaerosol supply unit can supply bioaerosol using a vibrating mesh spray to prevent damage to the bioaerosol.

[0079] In another example, the system may include a sensor (600) for measuring air quality in the receiving space. Examples of the sensor (600) include a temperature sensor, a humidity sensor, a carbon dioxide sensor, a fine dust sensor, a gas sensor, and the like. The measurement results of the sensor (600) may be transmitted to the monitoring unit (300) in real time. Users can check changes in the air quality within the receiving space in real time, as well as changes in the motion or image of the organism, thereby helping users identify the correlation between sample aerosol and air quality.

[0080] In one specific example, the chamber (100) may include a ventilation fan (700) that supplies outside air to the receiving space and discharges the inside air of the receiving space to the outside, and may include a control unit (800) that controls the operation of at least one of the ventilation fan (700), the supply unit (200), and the contaminant supply unit (500) based on the measurement results of the sensor (600).

[0081] The chamber system according to the present invention may further include a filter unit for purifying internal air discharged to the outside from the ventilation fan (700). The filter unit may include an air filter. The air filter may have the function of selectively removing specific gases. Since the performance of the air filter may deteriorate over time, an alarm unit may be provided to notify the filter replacement cycle.

[0082] For example, the control unit (800) may include a first mode that turns on the operation of at least one of the ventilation fan (700), the supply unit (200), and the pollutant supply unit (500) when the measurement result of the sensor (600) exceeds a set reference value, and a second mode that turns off the operation of at least one of the ventilation fan (700), the supply unit (200), and the pollutant supply unit (500) when the measurement result of the sensor (600) does not exceed a set reference value.

[0083] The above control unit (800) can control the rotation speed of the ventilation fan (700) through the first and second modes, or control the supply amount of the sample aerosol supplied from the supply unit (200) and the supply amount of the gaseous pollutant supplied from the pollutant supply unit (500). The first mode can increase or decrease the rotation speed of the ventilation fan (700), increase or decrease the supply amount of the gaseous pollutant, and increase or decrease the supply amount of the sample aerosol depending on the degree to which the measurement result of the sensor (600) exceeds a set reference value.

[0084] The above control unit (800) may include a user interface that allows the user to directly control the operation of the ventilation fan (700). This allows the user to adjust the environment of the receiving space to suit his or her research purposes.

[0085] In one example, the chamber (100) may include a collection unit (900) for collecting a sample candidate comprising at least one of a sample aerosol and a gaseous contaminant supplied to the receiving space.

[0086] The above collection unit (900) may be installed at least one of the front and rear ends of the chamber (100). In addition, the collection unit (900) may collect sample candidates in a gaseous or liquid state.

[0087] The above collection unit (900) can use various known equipment that can be used for gas or liquid collection without limitation, and examples thereof include a collection substrate, a gas bag sampling for gas collection, and a liquefaction device for liquid collection.

[0088] The above analysis unit (400) can perform physical, chemical and biological analysis of sample aerosols and gaseous pollutants through a sample candidate group collected from the collection unit.

[0089]

[0090] Below, a chamber system capable of studying the effects of sample aerosols on living organisms is briefly described with reference to the drawings.

[0091] Figures 2 and 3 are drawings to aid in understanding of a chamber system capable of studying the effects of sample aerosols on animals.

[0092] In one embodiment, the behavioral patterns of a live animal (P, e.g., a lizard, a rat, etc.) exposed to a sample aerosol were analyzed using a chamber system according to the present invention.

[0093] Referring to Fig. 2, a chamber (100) containing a living animal (P) was prepared, and a sample aerosol (S) was supplied to the receiving space of the chamber (100) through a supply unit (200). Then, as shown in Fig. 3, the receiving space of the chamber (100) was converted into 2D through a monitoring unit (300), and the starting position (A), movement path (B), and arrival position (C) of the living animal (P) were displayed on the converted 2D map.

[0094] Additionally, through the monitoring unit (300), the time that a living animal (P) stays at a specific location as well as its location is displayed on a 2D map. For example, a location where the animal stays for a relatively long time is displayed in a light color, and a location where the animal stays for a relatively short time is displayed in a dark color.

[0095] Additionally, the analysis unit (400) stores the movement patterns of living animals (P) and analyzes the toxicity of the sample aerosol (S) based on the tendencies of the stored movement patterns. For example, the analysis unit (400) analyzed that sample aerosols exhibiting similar movement pattern tendencies exhibit similar toxicity.

[0096]

[0097] Figures 4 and 5 are drawings to help understand the chamber system that can study the effects of sample aerosols on plants.

[0098] In another embodiment, the growth patterns of plants exposed to sample aerosols were analyzed using a chamber system according to the present invention.

[0099] Figure 4 (a) shows a chamber system that does not supply sample aerosol, Figure 4 (b) shows a chamber system that supplies sample aerosol, and Figure 5 shows the results of analyzing the growth patterns of plants grown in the chamber systems of Figures 4 (a) and (b).

[0100] First, as shown in (a) of Fig. 4, a chamber (100) containing plants as a control group was prepared, and no sample aerosol was supplied to the chamber (100).

[0101] As an experimental group, a chamber (100) containing plants was prepared as shown in (b) of Fig. 4, and sample aerosol (S) was supplied to the receiving space of the chamber (100) through a supply unit (200). Then, as shown in Fig. 5, changes in leaf length, leaf width, and leaf area over time were monitored through a monitoring unit (300).

[0102] The above analysis unit (400) analyzed that the sample aerosol supplied in (b) of FIG. 4 inhibits plant growth based on the results of FIG. 5. In addition, the analysis unit (400) stored the results of FIG. 5 and analyzed the toxicity of the sample aerosol (S) based on the trends of the stored graph.

[0103] For example, the above analysis unit (400) analyzed that sample aerosols showing similar graph trends exhibit similar toxicity.

[0104]

[0105] The preferred embodiments of the present invention described above are disclosed for the purpose of illustration, and those skilled in the art having ordinary knowledge of the present invention will be able to make various modifications, changes, and additions within the spirit and scope of the present invention, and such modifications, changes, and additions should be considered to fall within the scope of the following claims.

[0106] Description of the symbol

[0107] 100: Chamber

[0108] 200: Supply Department

[0109] 300: Monitoring Department

[0110] 400: Analysis Department

Claims

1. A chamber having a holding space for accommodating a living organism; A supply unit for supplying sample aerosol to a living organism within the receiving space; A monitoring unit for monitoring motion changes or image changes of a living organism before and after sample aerosol supply; and A chamber system including an analysis unit that analyzes the biological relevance of a sample aerosol and a living organism based on the monitoring results.

2. A chamber system in accordance with claim 1, wherein the sample aerosol comprises at least one of solid particles, liquid particles, and composite particles comprising a combination of liquid particles and solid particles.

3. A chamber system in the second paragraph, wherein the solid particles include metal particles or non-metal particles.

4. A chamber system in the second paragraph, wherein the liquid particles include an organic compound, an inorganic compound, or a mixture thereof.

5. A chamber system in accordance with claim 1, wherein the supply unit includes a production unit that produces a sample aerosol.

6. A chamber system according to claim 1, further comprising a contaminant supply unit configured to supply gaseous contaminants to living organisms within the receiving space.

7. A chamber system in accordance with claim 6, wherein the gaseous pollutant comprises at least one selected from the group consisting of carbon monoxide, carbon dioxide, formaldehyde, nitrogen dioxide, sulfur dioxide, hydrogen sulfide, volatile organic compounds, aromatic hydrocarbons, methylene chloride, ethylene chloride, ammonia, ozone, naphthalene, and radon.

8. A chamber system comprising a sensor for measuring air quality of the receiving space in accordance with paragraph 6.

9. In the 8th paragraph, the chamber includes a ventilation fan that supplies outside air to the receiving space and exhausts the inside air of the receiving space to the outside. A chamber system comprising a control unit that controls the operation of at least one of a ventilation fan, a supply unit, and a contaminant supply unit based on the measurement results of the above sensor.

10. In the 9th paragraph, the control unit is configured to: a first mode for turning on at least one of the ventilation fan, the supply unit, and the pollutant supply unit when the measurement result of the sensor exceeds a set reference value; and A chamber system comprising a second mode for turning off at least one of the ventilation fan and the contaminant supply unit if the measurement result of the above sensor does not exceed a set reference value.

11. A chamber system in accordance with claim 7, wherein the chamber includes a collection section for collecting a sample candidate group including at least one of a sample aerosol and a gaseous contaminant supplied to the receiving space.

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