Neural stimulation device and optimal electrode search method for neural stimulation

Abstract

Disclosed are a method for searching for an optimal electrode with which to provide electrical stimulation to a target nerve, and a neural stimulation device for providing electrical stimulation by searching for the optimal electrode. The disclosed invention comprises: neural memory; at least one processor electrically connected to the memory; and a neural stimulation patch attached to the skin of a user and including a plurality of electrode pairs for providing electrical stimulation, wherein the processor collects biometric information of the user generated from the electrical stimulation and searches for an optimal electrode pair with which to provide the electrical stimulation to a target nerve among electrodes included among the plurality of electrode pairs.

Description

Neurostimulation device and method for finding optimal electrodes for neurostimulation

[0001] The present invention relates to a nerve stimulation device and an optimal electrode search method for nerve stimulation.

[0002]

[0003] Various attempts are being made to treat medical conditions in patients by electrically stimulating nerves.

[0004] Methods for stimulating nerves can be broadly categorized into invasive and non-invasive methods. Invasive methods involve inserting a device into the body to directly electrically stimulate nerves. These methods are used to alleviate major symptoms of conditions such as chronic obstructive pulmonary disease (COPD) and to treat various conditions by controlling breathing.

[0005] Non-invasive methods are methods that stimulate nerves by applying electrical stimulation to the skin of the human body using electrodes without inserting a device into the body. Since they can reduce the side effects that occur with invasive nerve stimulation methods, they are being actively developed recently.

[0006] However, since noninvasive electrical stimulation methods cannot directly apply electrical stimulation to the nerves under the skin, a method for finding the optimal location to apply electrical stimulation is required.

[0007]

[0008] The present invention provides a method for searching for an optimal electrode capable of effectively providing non-invasive electrical stimulation to a target nerve, and a nerve stimulation device for searching for an optimal electrode and providing electrical stimulation.

[0009] In particular, the present invention provides a method for searching for an optimal electrode capable of effectively providing non-invasive electrical stimulation to the phrenic nerve and a nerve stimulation device for searching for an optimal electrode and providing electrical stimulation.

[0010]

[0011] According to one embodiment of the present invention for achieving the above object, a nerve stimulation device is provided, comprising: a memory; at least one processor electrically connected to the memory; and a nerve stimulation patch attached to a user's skin and including a plurality of electrode pairs for providing electrical stimulation, wherein the processor collects the user's biometric information according to the electrical stimulation and searches for an optimal electrode pair for providing the electrical stimulation to a target nerve among the electrodes included in the plurality of electrode pairs.

[0012] In addition, according to another embodiment of the present invention for achieving the above-mentioned purpose, a method for searching for an optimal electrode for nerve stimulation is disclosed, including the steps of collecting a user's biometric information according to electrical stimulation provided by a plurality of electrode pairs in contact with the user's skin; and using the biometric information, searching for an optimal electrode pair for providing the electrical stimulation to a target nerve among electrodes included in the plurality of electrode pairs.

[0013]

[0014] According to one embodiment of the present invention, by monitoring bio-information according to electrical stimulation provided to a target nerve, an optimal electrode can be searched, and by searching for an optimal electrode that provides electrical stimulation to the target nerve, electrical stimulation can be efficiently provided to the target nerve.

[0015] In particular, according to one embodiment of the present invention, by monitoring bio-information about the diaphragm and respiration according to phrenic nerve stimulation, an optimal electrode capable of efficiently providing electrical stimulation to the phrenic nerve can be searched.

[0016]

[0017] FIG. 1 is a drawing for explaining an electrical stimulation system according to one embodiment of the present invention.

[0018] FIG. 2 is a drawing for explaining a nerve stimulation device according to one embodiment of the present invention.

[0019] FIG. 3 is a drawing for explaining a stimulus providing method for searching for an optimal electrode pair according to one embodiment of the present invention.

[0020] FIG. 4 is a diagram for explaining a stimulus providing method for searching for an optimal electrode pair according to another embodiment of the present invention.

[0021] FIG. 5 is a drawing for explaining an optimal electrode search method for nerve stimulation according to one embodiment of the present invention.

[0022]

[0023] The present invention is susceptible to various modifications and embodiments. Specific embodiments are illustrated in the drawings and described in detail in the detailed description. However, this is not intended to limit the present invention to specific embodiments, but rather to encompass all modifications, equivalents, and alternatives falling within the spirit and technical scope of the present invention. Throughout the description of each drawing, similar reference numerals have been used to designate similar components.

[0024] Hereinafter, embodiments according to the present invention will be described in detail with reference to the attached drawings.

[0025]

[0026] FIG. 1 is a drawing for explaining an electrical stimulation system according to one embodiment of the present invention.

[0027] Referring to FIG. 1, an electrical stimulation system according to one embodiment of the present invention includes a nerve stimulation device (110) and a monitoring device (120). In addition, depending on the embodiment, a ventilator (130) may be further included.

[0028] A nerve stimulation device (110) is attached to the user's skin and non-invasively provides electrical stimulation to the user's target nerve, and includes a plurality of electrode pairs that provide the electrical stimulation. Here, the target nerve may be, for example, the phrenic nerve. Since the phrenic nerve is connected to the diaphragm through the neck, the nerve stimulation device (110) may be attached to the user's neck. In addition, since a pair of phrenic nerves are connected to the diaphragm through the neck, two nerve stimulation devices (110) may be attached to the user's neck to provide electrical stimulation to each phrenic nerve.

[0029] The nerve stimulation device (110) can search for an optimal electrode pair that provides electrical stimulation to a user's target nerve among electrodes included in a plurality of electrode pairs, and then provide electrical stimulation to the target nerve using the optimal electrode pair.

[0030] The monitoring device (120) monitors the user's biometric information and can monitor information about the user's breathing or diaphragm movement generated by electrical stimulation of the phrenic nerve. When stimulation is applied to the phrenic nerve, the diaphragm contracts and relaxes, inducing the user's breathing.

[0031] The monitoring device (120) may be, for example, an electromyography sensor device that collects electromyography values ​​of the diaphragm, an ultrasound device that generates an ultrasound image of the diaphragm, a flow meter that collects information on the user's respiratory volume, or a microphone that measures respiratory sounds generated by the user's breathing. The electromyography sensor device or the ultrasound device may be attached to the abdomen where the user's diaphragm is located, and the flow meter may be installed in an artificial respirator (130) described below. In addition, the microphone may be installed in various locations that can measure the user's respiratory sounds, and as an example, it may be located on the neck to efficiently obtain biometric information such as respiratory sounds, and may be located in the same location as the nerve stimulation device (110).

[0032] As described above, the nerve stimulation device (110) performs an optimal electrode search process, and at this time, information about the monitored user's breathing or information about the movement of the diaphragm is provided from the monitoring device (120), and the optimal electrode pair can be searched. Through the optimal electrode pair search process, the nerve stimulation device (110) can determine an optimal electrode pair among electrodes included in a plurality of electrode pairs, and provide electrical stimulation to the phrenic nerve using the optimal electrode pair. Depending on the embodiment, the optimal electrode pair may be one or multiple, and a specific optimal electrode pair search method is described in more detail with reference to FIGS. 2 to 4.

[0033] A ventilator (130) can be used to facilitate the user's breathing when the user's breathing is induced by stimulation of the phrenic nerve. The ventilator (130) can be synchronized with the user's breathing cycle to provide the user with the air necessary for breathing.

[0034] Because user breathing induction through phrenic nerve stimulation can activate the lymphatic system and cerebrospinal fluid flow, it can be applied to degenerative brain diseases such as dementia and Parkinson's disease, stroke, brain edema, hydrocephalus, and other brain diseases, and can also be used as a treatment for lymphatic system and related immune diseases.

[0035]

[0036] FIG. 2 is a drawing for explaining a nerve stimulation device according to one embodiment of the present invention.

[0037] A neurostimulation device according to one embodiment of the present invention comprises a memory, at least one processor electrically connected to the memory, and a neurostimulation patch. The memory and processor may be designed to be incorporated into the neurostimulation patch.

[0038] Referring to FIG. 2, a nerve stimulation patch (210) according to one embodiment of the present invention includes a plurality of electrode pairs (220) that provide electrical stimulation and are attached to the user's skin. Each electrode pair (220) includes a positive electrode and a negative electrode and may be in a protruding shape so that pressure can be applied to the skin when the nerve stimulation patch (210) is attached to the skin. FIG. 2 illustrates an embodiment in which five electrode pairs are used, and the number of electrode pairs may vary depending on the embodiment.

[0039] The processor collects the user's biometric information based on electrical stimulation, and searches for an optimal electrode pair, consisting of an anode and a cathode electrode, among the electrodes included in a plurality of electrode pairs, to provide electrical stimulation to the target nerve. The processor can provide electrical stimulation to the target nerve using the electrode selected from the plurality of electrode pairs, and collect the user's biometric information. In one embodiment, the processor can receive biometric information collected by the monitoring device from the monitoring device.

[0040] The target nerve may be the phrenic nerve, and the nerve stimulation patch (210) may be attached to the user's neck. In order to stimulate a pair of phrenic nerves located in the neck, two nerve stimulation patches (210) may be attached to the user's neck, and each processor of the nerve stimulation patches may independently search for an optimal electrode pair. Furthermore, as described above, the bio-information may include diaphragmatic electromyography values, diaphragmatic movement information acquired through ultrasound, information on the user's respiratory volume acquired through a flow meter, or information on respiratory sounds generated by the user's breathing.

[0041] Depending on the location of the electrode providing the electrical stimulation, the electrical stimulation can be provided precisely to the phrenic nerve or near the phrenic nerve. If the electrical stimulation is provided near the phrenic nerve, the phrenic nerve is weakly stimulated, making it difficult to induce strong breathing in the user. Therefore, the processor searches for an optimal electrode pair that can provide the electrical stimulation to the exact location of the phrenic nerve through an optimal electrode pair search process.

[0042] As an example, the processor may determine an electrode pair in which a diaphragm EMG value exhibits a maximum value as an optimal electrode pair, or an electrode pair in which a diaphragm movement displacement exhibits a maximum value as an optimal electrode pair. When electrical stimulation is accurately provided to the phrenic nerve, the displacement of the diaphragm increases due to contraction and relaxation of the diaphragm, and when the displacement of the diaphragm increases, the diaphragm EMG value also increases. Therefore, the processor may determine the optimal electrode pair using the diaphragm EMG value or the movement displacement of the diaphragm. The movement displacement of the diaphragm may be calculated from diaphragm movement information acquired through ultrasound.

[0043] In addition, the processor may determine, as an example, an electrode pair indicating a maximum user's respiratory volume or an electrode pair indicating a maximum user's respiratory sound volume as the optimal electrode pair. As described above, when electrical stimulation is accurately provided to the phrenic nerve, the displacement of the diaphragm increases due to contraction and relaxation of the diaphragm, thereby increasing the respiratory volume. Therefore, the processor may determine the optimal electrode pair using the user's respiratory volume or respiratory sound volume. The user's respiratory volume may be calculated from the user's respiratory volume information obtained through a flow meter, and the respiratory sound volume may be calculated from information about the respiratory sound.

[0044] According to one embodiment of the present invention, by monitoring bio-information according to electrical stimulation provided to a target nerve, an optimal electrode can be searched, and by searching for an optimal electrode that provides electrical stimulation to the target nerve, electrical stimulation can be efficiently provided to the target nerve.

[0045] In particular, according to one embodiment of the present invention, by monitoring bio-information about the diaphragm and respiration according to phrenic nerve stimulation, an optimal electrode capable of efficiently providing electrical stimulation to the phrenic nerve can be searched.

[0046]

[0047] FIG. 3 is a drawing for explaining a stimulus providing method for searching for an optimal electrode pair according to one embodiment of the present invention, and FIG. 3 illustrates electrodes placed on a cross-section of the neck.

[0048] The processor of a nerve stimulation device according to one embodiment of the present invention can provide electrical stimulation to a target nerve using a pair of electrodes selected from among electrodes included in a plurality of electrode pairs to search for an optimal electrode pair as described above, and collect bio-information according to the electrical stimulation.

[0049] At this time, the processor can sequentially activate one of the plurality of electrode pairs according to a preset stimulus provision order to collect biometric information. The activated electrode pair provides electrical stimulation to the target nerve. For example, if the nerve stimulation patch includes the first to fifth electrode pairs, the processor can activate the electrode pairs in the order of the first to fifth electrode pairs to provide electrical stimulation to the target nerve.

[0050] Alternatively, the processor may collect biometric information by selectively activating one positive electrode and one negative electrode among the electrodes included in a plurality of electrode pairs. For example, if the first to fifth electrode pairs are included in the nerve stimulation patch, the processor may selectively activate one of the positive electrodes included in the first to fifth electrode pairs and one of the negative electrodes included in the first to fifth electrode pairs to provide electrical stimulation to the target nerve. Each of the electrodes (310 to 350) illustrated in FIG. 3 represents one of the positive electrodes and negative electrodes of the first to fifth electrode pairs.

[0051] Since the electrical stimulation signal that provides the electrical stimulation proceeds from the anode electrode through the neck (300) toward the cathode electrode, as shown in the dotted line in Fig. 3, when the electrodes are arranged as in Fig. 3, when the electrical stimulation is provided through the electrodes (320, 330) selected from each of the second and third electrode pairs, the electrical stimulation can be provided to the location of the phrenic nerve (301). Accordingly, the anode electrode selected from the second electrode pair and the cathode electrode (330) selected from the third electrode pair, or the cathode electrode (320) selected from the second electrode pair and the anode electrode selected from the third electrode pair, can be determined as the optimal electrode pair.

[0052] As described above, a pair of phrenic nerves are connected to the diaphragm through the neck. In FIG. 3, for convenience of explanation, a method for finding an optimal electrode pair for one phrenic nerve is described as an example, and the search for an optimal electrode pair for another phrenic nerve can also be performed in the same manner as the above-described example.

[0053] Meanwhile, according to an embodiment, the selected electrode can provide electrical stimulation by changing the intensity of the electrical stimulation at multiple stimulation intensity levels, and the processor can collect bio-information for each of the multiple stimulation intensity levels.

[0054]

[0055] FIG. 4 is a drawing for explaining a stimulus providing method for searching for an optimal electrode pair according to another embodiment of the present invention, in which first and second electrode pairs arranged on a cross-section of the neck are illustrated.

[0056] A processor of a nerve stimulation device according to an embodiment of the present invention can collect biometric information by selectively activating a first and a second electrode pair among electrodes included in a plurality of electrode pairs. That is, the processor can provide electrical stimulation to a target nerve using two pairs of electrodes selected from among the electrodes included in the plurality of electrode pairs. At this time, each of the first and second electrode pairs may be two electrode pairs selected from among the plurality of electrode pairs, or two electrode pairs including one positive electrode and one negative electrode selected from among the electrodes included in the plurality of electrode pairs.

[0057] The electrical stimulation provided by the first and second electrode pairs is an alternating current electrical stimulation, and the frequency of the electrical stimulation provided by the first electrode pair may be different from the frequency of the electrical stimulation provided by the second electrode pair. For example, the first electrode pair may provide an electrical stimulation of 2000 Hz, and the second electrode pair may provide an electrical stimulation of 2010 Hz.

[0058] The processor can search for the optimal electrode pair by utilizing the beat phenomenon between the electrical stimulations of different frequencies provided by the first and second electrode pairs. Since the amplitude of the electrical stimulation signal increases due to the beat, if the area where the electrical stimulation signals overlap corresponds to the location of the phrenic nerve, a strong stimulation can be provided to the phrenic nerve. In the example described above, a 10 Hz electrical stimulation can be applied to the phrenic nerve.

[0059] FIG. 4 illustrates an embodiment in which electrical stimulation is provided by a first electrode pair (411, 412) and a second electrode pair (421, 422) selected from among electrodes included in a plurality of electrode pairs. A dotted line connecting a pair of electrodes represents an electrical stimulation signal provided by the first and second electrode pairs (411, 412, 421, 422), and the direction in which the electrical stimulation signal propagates may vary depending on the positions of the electrodes included in the first and second electrode pairs (411, 412, 421, 422).

[0060] As illustrated in Fig. 4, the first and second electrode pairs when the area (430) where the electrical stimulation signals overlap corresponds to the location of the phrenic nerve (301) of the neck (300) can be determined as the optimal electrode pair.

[0061] According to an embodiment, at least one of the first and second electrode pairs can provide electrical stimulation by varying the intensity of the electrical stimulation at multiple stimulation intensity levels, and the processor can collect bio-information for each of the multiple stimulation intensity levels.

[0062] The position of the area (430) where the electrical stimulation signals overlap through the beat phenomenon corresponds to the position where the intensity of the electrical stimulation provided by the first and second electrode pairs (411, 412, 421, 422) is the same. For example, if the intensity of the electrical stimulation provided by the first electrode pair (411, 412) is greater than the intensity of the electrical stimulation provided by the second electrode pair (421, 422), the position of the area (430) where the electrical stimulation signals overlap moves to the right, and conversely, if the intensity of the electrical stimulation provided by the first electrode pair (411, 412) is greater than the intensity of the electrical stimulation provided by the second electrode pair (421, 422), the position of the area (430) where the electrical stimulation signals overlap moves to the left.

[0063] Accordingly, the processor can adjust the stimulation location of the phrenic nerve by changing the intensity of the electrical stimulation provided by at least one of the first and second electrode pairs, and can determine the intensity of the electrical stimulation for stimulating the phrenic nerve using the bio-information collected for each of a plurality of stimulation intensity levels.

[0064] Meanwhile, as described above, a pair of phrenic nerves are connected to the diaphragm through the neck. In FIG. 4, for convenience of explanation, a method for finding an optimal electrode pair for one phrenic nerve is described as an example, and the search for an optimal electrode pair for another phrenic nerve can also be performed in the same manner as the above-described example.

[0065]

[0066] FIG. 5 is a drawing for explaining an optimal electrode search method for nerve stimulation according to one embodiment of the present invention, and FIG. 5 explains an optimal electrode search method of the aforementioned nerve stimulation device as one embodiment.

[0067] Referring to FIG. 5, a nerve stimulation device according to an embodiment of the present invention collects user's bio-information based on electrical stimulation provided by a plurality of electrode pairs in contact with the user's skin (S510). Here, the target nerve may be the phrenic nerve, and the bio-information may include diaphragm electromyography values, diaphragm movement information acquired through ultrasound, user's respiratory volume information acquired through a flow meter, or information on breathing sounds generated by the user's breathing.

[0068] In step S510, the nerve stimulation device can provide electrical stimulation to the user by selecting one of a plurality of electrode pairs or selecting one positive electrode and one negative electrode from among the electrodes included in the plurality of electrode pairs according to a preset stimulation provision order.

[0069] Alternatively, the neurostimulation device may provide electrical stimulation to the user by selecting a first and second electrode pairs from among a plurality of electrode pairs. In this case, the frequency of the electrical stimulation provided by the first electrode pair may be different from the frequency of the electrical stimulation provided by the second electrode pair.

[0070] Additionally, each of the first and second electrode pairs may include one anode electrode and one cathode electrode selected from among the electrodes included in the plurality of electrode pairs, and at least one of the first and second electrode pairs may provide electrical stimulation by varying the intensity of the electrical stimulation at a plurality of stimulation intensity levels.

[0071] And the nerve stimulation device uses biometric information to search for an optimal electrode pair that will provide electrical stimulation to a target nerve among the electrodes included in a plurality of electrode pairs (S520).

[0072] The neurostimulation device may determine the electrode pair that exhibits the maximum diaphragm EMG value as the optimal electrode pair, or the electrode pair that exhibits the maximum diaphragm movement displacement as the optimal electrode pair. Alternatively, the neurostimulation device may determine the electrode pair that exhibits the maximum user's respiratory volume as the optimal electrode pair, or the electrode pair that exhibits the maximum user's respiratory sound volume as the optimal electrode pair.

[0073]

[0074] The technical contents described above may be implemented in the form of program commands that can be executed through various computer means and recorded on a computer-readable medium. The computer-readable medium may include program commands, data files, data structures, etc., alone or in combination. The program commands recorded on the medium may be those specially designed and configured for the embodiments, or may be those known to and available to those skilled in the art of computer software. Examples of computer-readable recording media include magnetic media such as hard disks, floppy disks, and magnetic tapes, optical media such as CD-ROMs and DVDs, magneto-optical media such as floptical disks, and hardware devices specially configured to store and execute program commands, such as ROMs, RAMs, and flash memories. Examples of program commands include not only machine language codes generated by a compiler, but also high-level language codes that can be executed by a computer using an interpreter, etc. The hardware devices may be configured to operate as one or more software modules to perform the operations of the embodiments, and vice versa.

[0075]

[0076] Although the present invention has been described with reference to specific details such as specific components and limited embodiments and drawings, these have been provided only to help a more general understanding of the present invention, and the present invention is not limited to the above embodiments, and those with ordinary skill in the art to which the present invention pertains can make various modifications and variations based on these descriptions. Therefore, the spirit of the present invention should not be limited to the described embodiments, and all things that are equivalent or equivalent to the following claims as well as the claims are considered to fall within the scope of the spirit of the present invention.

Claims

1. Memory; At least one processor electrically connected to the memory; and A neurostimulation patch that is attached to the user's skin and includes a plurality of electrode pairs that provide electrical stimulation, The above processor Collecting the user's bio-information according to the electrical stimulation, and searching for the optimal electrode pair that will provide the electrical stimulation to the target nerve among the electrodes included in the plurality of electrode pairs. Neurostimulation device.

2. In paragraph 1, The above target nerve is The phrenic nerve Neurostimulation device.

3. In paragraph 2, The above biometric information Includes diaphragm electromyography values, The above processor The electrode pair that shows the maximum value of the diaphragm electromyography value is determined as the optimal electrode pair. Neurostimulation device.

4. In paragraph 2, The above biometric information Contains diaphragm movement information acquired through ultrasound, The above processor The electrode pair that shows the maximum movement displacement of the diaphragm is determined as the optimal electrode pair. Neurostimulation device.

5. In paragraph 2, The above biometric information Contains the user's respiratory volume information obtained through a flow meter, The above processor, The electrode pair that shows the maximum breathing volume of the user is determined as the optimal electrode pair. Neurostimulation device.

6. In paragraph 2, The above biometric information Contains information about breathing sounds generated by the user's breathing, The above processor, The electrode pair that shows the maximum breathing sound volume of the user is determined as the optimal electrode pair. Neurostimulation device.

7. In paragraph 1, The above processor According to a preset stimulus provision order, one of the plurality of electrode pairs is sequentially activated to collect the bio-information. Neurostimulation device.

8. In paragraph 1, The above processor Collecting the bio-information by selectively activating one positive electrode and one negative electrode among the electrodes included in the plurality of electrode pairs Neurostimulation device.

9. In paragraph 1, The above processor Among the electrodes included in the plurality of electrode pairs, the first and second electrode pairs are selectively activated to collect the biometric information, The frequency of the electrical stimulation provided by the first electrode pair is A frequency different from the frequency of the electrical stimulation provided by the second electrode pair. Neurostimulation device.

10. In paragraph 9, Each of the first and second electrode pairs Among the electrodes included in the above plurality of electrode pairs, one positive electrode and one negative electrode are selected. Neurostimulation device.

11. A step of collecting the user's biometric information according to electrical stimulation provided by multiple electrode pairs in contact with the user's skin; and A step of searching for an optimal electrode pair that will provide the electrical stimulation to the target nerve among the electrodes included in the plurality of electrode pairs using the above biometric information. An optimal electrode search method for neural stimulation including .

12. In paragraph 11, The above target nerve is The phrenic nerve A method for finding optimal electrodes for nerve stimulation.

13. In paragraph 11, The above biometric information Includes diaphragm electromyography values, The step of searching for the above optimal electrode pair is The electrode pair that shows the maximum value of the diaphragm electromyography value is determined as the optimal electrode pair. A method for finding optimal electrodes for nerve stimulation.

14. In paragraph 11, The above biometric information Contains diaphragm movement information acquired through ultrasound, The step of searching for the above optimal electrode pair is The electrode pair that shows the maximum movement displacement of the diaphragm is determined as the optimal electrode pair. A method for finding optimal electrodes for nerve stimulation.

15. In paragraph 11, The above biometric information Contains the user's respiratory volume information obtained through a flow meter, The step of searching for the above optimal electrode pair is The electrode pair that shows the maximum breathing volume of the user is determined as the optimal electrode pair. A method for finding optimal electrodes for nerve stimulation.

16. In paragraph 11, The above biometric information Contains information about breathing sounds generated by the user's breathing, The step of searching for the above optimal electrode pair is The electrode pair that shows the maximum breathing sound volume of the user is determined as the optimal electrode pair. A method for finding optimal electrodes for nerve stimulation.

17. In paragraph 11, The step of collecting the user's biometric information is According to a preset stimulus provision order, one of the plurality of electrode pairs is selected to provide the electrical stimulation to the user. An optimal electrode search method for neural stimulation including:

18. In paragraph 11, The step of collecting the user's biometric information is Selecting one positive electrode and one negative electrode from among the electrodes included in the plurality of electrode pairs to provide the electrical stimulation to the user. A method for finding optimal electrodes for nerve stimulation.

19. In paragraph 11, The step of collecting the user's biometric information is Among the plurality of electrode pairs, the first and second electrode pairs are selected to provide the electrical stimulation to the user, The frequency of the electrical stimulation provided by the first electrode pair is A frequency different from the frequency of the electrical stimulation provided by the second electrode pair. A method for finding optimal electrodes for nerve stimulation.

20. In paragraph 19, Each of the first and second electrode pairs It comprises one anode electrode and one cathode electrode selected from among the electrodes included in the above plurality of electrode pairs, At least one of the first and second electrode pairs By changing the intensity of the electrical stimulation at multiple stimulation intensity levels, the electrical stimulation is provided. A method for finding optimal electrodes for nerve stimulation.

Images