Propolis virucidal oral spray

WO2025209614A8PCT designated stage Publication Date: 2025-10-30GR NANO AS
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Patent Information

Application Number
PCT/CZ2025/050027
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-03-31
Filing Date
2025-03-28
Publication Date
2025-10-30

AI Technical Summary

Technical Problem

Existing products do not effectively utilize the virucidal potential of propolis to protect the oral and nasal cavities from infections by coronavirus and other pathogens.

Method used

A propolis extract formulation containing 16.1-18.1% propolis, 72.5% ethanol enriched with menthol, and 0.01% quaternary ammonium salt, applied as a spray to form a protective film on mucous membranes, utilizing the virucidal properties of propolis.

Benefits of technology

The formulation provides a protective coating that neutralizes bacteria and viruses, offering effective protection against coronavirus and other pathogens by forming a shield on oral and nasal cavities.

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Abstract

The technical solution relates to a propolis virucidal oral spray, which contains 16.1 % to 18.1 % by weight of propolis extract, and 72.5 % by weight of ethanol enriched with menthol and the remainder up to 100 % by weight of the mixture is water. The preparation, applied in the form of a spray, forms a protective film (liquid veil) on the mucous membrane of the mouth and nose, which protects the user from infection.
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Description

[0001] Propolis virucidal oral spray

[0002] Technical field

[0003] The technical solution relates to a preparation which uses active substances of natural origin contained in propolis to provide protection from infection by coronavirus and other pathogens. The preparation, applied in the form of a spray, forms a protective film (liquid mask) on the mucous membrane of the mouth and nose which protects the user from infection.

[0004] Background art

[0005] Currently, numerous products and preparations are known, the basis of which is propolis and the substances contained in it. The positive effect on the human body, proven by many years of experience in the field of increasing the immune system, is used as a part of cosmetic products and in numerous other fields, without specifically using the potential of propolis extract in the field of virucidal effects aimed at protecting the oral and nasal cavities.

[0006] Principle of technical solution

[0007] The virucidal effects of propolis and the substances contained therein are utilized by the preparation according to this technical solution, which contains 16.1 % to 18.1 % by weight of propolis extract, and 72.5 % by weight of ethanol enriched with menthol, and the total mixture is supplemented to 100 % by weight with purified water, wherein the propolis extract contains 1.50 % by weight of propolis dissolved in 40.67 % by weight of ethanol enriched with menthol, supplemented to 100 % by weight with purified water.

[0008] In a preferred embodiment, the propolis extract further contains 0,01 % by weight of quaternary ammonium salt. Ethanol enriched with menthol contains a mixture of ethanol with a concentration of 96 % by volume, menthol and water in a ratio of 95 % by weight of ethanol, 1 % by weight of menthol, made up to 100% by weight with purified water.

[0009] Examples of embodiment of technical solution

[0010] Example 1

[0011] A propolis extract is mixed with ethanol enriched with menthol and the mixture thus prepared is supplemented with water (purified water). The mutual ratio of the individual components of the prepared mixture is shown in Table 1 and the composition of the propolis extract is shown in Table 2.

[0012] A CAS Registry Number is an internationally recognized unique identification number used in chemistry for chemical substances, polymers, biological sequences, mixtures and alloys.

[0013] Table 1 Table 2

[0014] Example 2

[0015] A propolis extract in an amount of 16.1 to 18.1 % by weight is mixed with ethanol enriched with menthol in an amount of 72.5 % by weight and the mixture thus obtained is supplemented with water (purified) to 100 % by weight. The mutual ratio of the individual components of the obtained mixture is shown in Table 3. The composition of the propolis extract is according to Table 2, or according to Table 4, where the propolis extract also contains a quaternary ammonium salt.

[0016] Table 3

[0017] Table 4 Industrial applicability

[0018] The technical solution has direct applicability for the purposes of prevention and protection of the human body from infection by coronavirus and other pathogenic organisms. It protects the user's oral and nasal cavities by creating a protective coating on the mucous membrane when applied, which has neutralizing effects and functions as a shield from bacteria and viruses.

Claims

CLAIMS1 . A propolis virucidal oral spray, characterized in that it contains 16.1 wt. % to 18.1 % by weight of a propolis extract, and 72.5 % by weight of ethanol enriched with menthol and the remainder up to 100 % by weight of the mixture is water, wherein the propolis extract contains 1 .50 % by weight of propolis dissolved in 40.67 % by weight of ethanol enriched with menthol, supplemented up to 100 % by weight with water.

2. The propolis virucidal oral spray according to claim 1 , wherein the propolis extract further contains 0.01 % by weight of quaternary ammonium salt.