Multi-patient tomography apparatus

Abstract

The present invention relates to a positron emission tomography apparatus configured to generate tomography images of at least one subject placed in an examination region.

Description

[0001] MULTI-PA TOMOGRAPHY DEVICE

[0002] FIELD OF INVENTION

[0003] The present invention relates to medical imaging devices, more particularly to preclinical imaging using positron emission tomography (PET).

[0004] STATE OF THE ART

[0005] Conventional Positron Emission Tomography (PET) devices have long been used for medical imaging, but have some significant drawbacks that limit their accessibility.

[0006] In terms of cost, traditional PET scanners require significant investment for both acquisition and maintenance, which can be a financial barrier to their installation for many healthcare facilities. Furthermore, these scanners typically have lengthy acquisition times, leading to delays in the imaging process and limiting the number of patients that can be treated within a given period. These cost and time constraints can compromise the profitability and efficiency of medical imaging services, particularly in environments with high demand for PET scans.

[0007] This has the direct consequence that PET scans are difficult for patients to access, or only with long waiting times, while demand continues to rise. Indeed, there is a growing demand for PET scans in the evaluation and monitoring of radiotherapy, chemotherapy, and immunotherapy. Furthermore, the increasingly early detection of diseases such as cancer should lead to improved treatment outcomes and a growing demand for follow-up scans in the near future. For example, PET imaging after cancer screening can be expected for breast, lung, or prostate cancer. PET imaging is therefore no longer limited to tumor detection and monitoring its spread (as was previously the case), but is increasingly playing a crucial role in early diagnosis.

[0008] In order to keep up with this trend (and meet clinical needs) without further increasing healthcare costs, imaging services will need the capacity to scan more patients in a given period.

[0009] Therefore, there is a need for more efficient and economical PET devices, capable of meeting the growing needs for patient diagnosis and monitoring, enabling in particular an increase in patient throughput.

[0010] SUMMARY

[0011] The present invention relates to a positron emission tomography apparatus configured to generate tomographic images of at least one subject placed in an examination region, the apparatus comprising: a radiation detection device arranged to view the examination region and comprising an axial axis z running longitudinally through the center of the detection device, a radial axis x perpendicular to the axial axis z and a tangential axis y perpendicular to both the axial axis z and the radial axis x; an examination platform extending along the axial axis z and inside the detection device, the examination platform comprising an examination area opposite the examination region and a setup area extending outside the examination region, the examination platform being configured to simultaneously accommodate at least two subjects, of which at least one subject is in the examination area;an image generation device for generating 3D or 4D images from signals detected by the detection device in the examination area. In one embodiment, the examination platform further comprises: a fixed support; a sliding platform disposed on the fixed support and comprising at least two sections arranged side by side along an axis of the detection device and configured to each accommodate a subject, at least one first section being disposed in the examination area and at least one second section being disposed in the installation area or in the examination area; a device for moving the sliding platform along an axis of the detection device configured to move at least one section from the installation area to the examination area.

[0012] In one embodiment, the at least two sections are arranged side by side along the radial axis of the detection device, and the sliding plane movement device is configured to move the sliding plane along the axial axis of the detection device so that the examination tray is configured to simultaneously accommodate at least two subjects in the examination area. In another embodiment, the at least two sections are arranged side by side along the axial axis of the detection device, and the sliding plane movement device is configured to move the sliding plane along the axial axis of the detection device, so that the examination tray is configured to simultaneously accommodate one subject in the examination area and one subject in the setup area.In one embodiment, the at least two sections are arranged side by side along the radial axis of the detection device, and the sliding plane movement device is configured to move the sliding plane along the radial axis of the detection device, such that the examination tray is configured to simultaneously accommodate at least two subjects in the examination region or to simultaneously accommodate one subject in the examination region and one subject in the setup area. In one embodiment, the examination tray comprises at least two rows of at least two sections along an axis of the detection device, preferably along the radial or axial axis of the detection device. In one embodiment, the tomography unit comprises at least two examination trays arranged side by side along the radial axis of the detection device.In one embodiment, the examination platform further comprises a fixed support with at least two sections arranged side-by-side along an axis of the detection device and configured to accommodate a subject, with at least one section located in the examination area and at least one section located in the setup area or the examination area. In one embodiment, the detection device has an axial dimension between 50 cm and 3 m. In one embodiment, the detection device has a radial dimension between 50 cm and 10 m. In one embodiment, the detection device has a tangential dimension between 20 cm and 1 m. In one embodiment, the positron emission tomography (PET) scanner further comprises a subject identification system.In one embodiment, the examination platform (12) is configured to accommodate at least four subjects simultaneously, including at least two subjects in the examination area (121).

[0013] The invention also relates to a method for generating tomography images of at least one subject placed in an examination area of ​​a positron emission tomography device, comprising: providing a positron emission tomography device according to the invention; installing at least two subjects, at least one of whom is in the examination area; and generating tomography images of at least one subject placed in the examination area.

[0014] In one embodiment, the method includes: a step of moving at least one subject from the installation area to the examination area; generation of tomography images of the subject moved in the examination area.

[0015] In one embodiment, the movement of the subject from the installation area to the examination area is achieved by moving the sliding plane and / or the detection device along the axial axis. DEFINITIONS

[0016] In the present invention, the terms below are defined as follows:

[0017] The "axial axis" (or longitudinal axis) refers to the main axis of a PET scanner that runs longitudinally through the center of the radiation detection device, preferably in a ring. This axis is parallel to the direction of movement of the scan platform. Detectors arranged along this axis capture positron emission data emitted by the radiopharmaceutical in the subject's body.

[0018] The "radial axis" (or transaxial axis) refers to an axis that is perpendicular to the axial axis and passes radially through the center of the radiation detection device. This axis defines the lateral or horizontal directions in the transverse plane. Transaxial images are generated using data captured along this axis, showing a cross-sectional view of the subject's body.

[0019] The "tangential axis" (or azimuthal axis) refers to an axis that is perpendicular to both the axial and radial axes. This axis defines the angular directions around the subject. The PET scanner can rotate around this axis to capture images from different angles, allowing for three-dimensional reconstruction of the data.

[0020] DETAILED DESCRIPTION

[0021] The present invention relates to a positron emission tomography (PET) device configured to generate tomography images of at least one subject placed in an examination region.

[0022] The device comprises: a radiation detection device arranged to view the examination area and comprising an axial axis running longitudinally through the center of the detection device, a radial axis perpendicular to the axial axis and a tangential axis perpendicular to both the axial and radial axes; an examination platform extending along the axial axis and within the detection device, the examination platform comprising an examination area opposite the examination area and a setup area extending outside the examination area, the examination platform being configured to simultaneously accommodate at least two subjects, with at least one subject in the examination area; an image generation device for generating 3D or 4D images from signals detected by the detection device in the examination area.

[0023] The fundamental principle of a PET scanner (also commonly called a PET scan) is based on the detection of gamma photons emitted during the annihilation of positrons in a subject's body. When a radiotracer, such as 18F-FDG (fluorodeoxyglucose labeled with fluorine-18), is injected into the body, it concentrates in areas of high metabolic activity, such as tumors or inflamed tissues. The positrons emitted by the radiotracer interact with electrons in the surrounding tissues, resulting in their mutual annihilation. This annihilation produces two gamma photons emitted in opposite directions with a characteristic energy of 511 keV. The PET scanner uses detectors positioned around the subject to detect these gamma photons. These detectors are typically made of scintillation crystals that emit light when a gamma photon passes through them.Photons emitted by scintillation crystals are converted into electrical signals by photodetectors. When gamma photons are detected simultaneously by multiple detectors around a subject, this indicates positron emission that has occurred along the imaginary line connecting these detectors. By collecting information about positron emissions from different directions, the PET scanner can reconstruct a three-dimensional image of the radiotracer's distribution within the subject's body. This image allows physicians to identify areas of abnormal metabolic activity, such as cancerous tumors, infections, or inflammatory lesions, and to assess the response to treatment. The scan area is defined as the spatial region in which the radiation emitted by the administered radiopharmaceutical (or radiotracer) can be detected by the detection device.

[0024] The aim of the invention is to make cancer screening by positron emission tomography (PET) technology compatible with a large target population (people aged 40 to 75) and / or to enable whole-body tumor molecular mapping (3-10 molecules characterizing lesions are studied for a subject).

[0025] The examination platform is configured to simultaneously accommodate at least two subjects, with at least one subject in the examination area (i.e., one subject in the examination area and one subject in the setup area, or two subjects in the examination area, preferably positioned side-by-side). The multi-patient PET scanner allows, in some cases, for one subject to be positioned while another subject undergoes a PET scan and / or for simultaneous PET scans to be performed on two subjects. More specifically, the PET scanner described below optimizes resource utilization by efficiently sharing available time and equipment to perform parallel PET scans, while ensuring accurate and reliable data acquisition for each subject.

[0026] The PET scanner described here offers the advantage of sharing the detection area. By allowing at least two subjects to be scanned in the same area, each subject benefits from a larger detection area, contributing to increased detection sensitivity. The detection sensitivity is thus four to six times greater than a conventional LAFOV PET scanner, sixty times greater than a SAFOV digital PET scanner, and 240 times greater than a SAFOV analog PET scanner. This allows, in particular, for a corresponding reduction in the administered radiotracer dose, making the technique suitable for mass screening and potentially virtually radiation-free.

[0027] The PET scanner described here also offers the advantage of sharing detection time. Indeed, by allowing at least two subjects to be placed in the same examination area, the PET scanner enables the simultaneous acquisition of images for multiple subjects. For example, a 5-minute PET scan for five subjects simultaneously positioned in the examination area is equivalent to acquiring one subject per minute if a conventional PET scanner were used (which is not possible because it would require increasing the administered dose by a factor of 5 for the same image quality).

[0028] Preferably, the examination platform is configured to simultaneously accommodate at least two subjects, with at least one subject in the examination area and one in the setup area. The PET scanner described here thus advantageously allows for the sharing of setup time. Indeed, by allowing one subject to be simultaneously in the examination area and one in the setup area, the PET scanner enables ultra-fast subject setup. Thus, one (or more) subject(s) are removed and another (or more) are positioned while the acquisition time of another subject is being taken. The time the PET scanner dedicates to detection is advantageously and considerably improved. By comparison, setup takes six minutes for a conventional LAFOV PET scanner and three minutes for a CT scanner with five minutes of acquisition time.With the PET scanner described here, it will take less than a minute to move a subject, previously positioned in the setup area, into the examination area and to remove the subject whose PET scan has been performed. The PET scanner's "downtime," i.e., the time without subject imaging, is thus minimized.

[0029] The invention therefore aims to accelerate the entire detection process, from the installation of the patient to the simultaneous detection of several subjects in order to consequently increase the examination rate, making it possible to manage a large volume of patients simultaneously or in a highly optimized flow.

[0030] For comparison, a conventional SAFOV (small axial field of view) PET scanner can perform PET scans on 12 to 30 patients per day, while a standard LAFOV PET scanner can perform PET scans on 40 to 50 patients per day. The multi-patient PET scanner described here offers the advantage of further increasing the daily patient throughput by combining the detection area, detection time, and setup time. For example, a medical imaging center equipped with a multi-patient PET scanner could potentially perform between 300 and 3,000 PET scans per day, depending on the number of subjects that can be simultaneously positioned in the setup area and the scan area.

[0031] The ability to simultaneously image multiple subjects with a single PET scanner offers numerous significant advantages in the field of medical imaging. First, this approach allows for more efficient use of resources, maximizing scanner uptime and reducing patient wait times. By enabling the simultaneous examination of multiple patients, imaging throughput is considerably increased, allowing for faster responses to patients' diagnostic and follow-up needs. Furthermore, this multi-patient PET scanner helps reduce operational costs by streamlining the use of equipment and associated human resources. In addition, simultaneous imaging of multiple patients can be particularly beneficial in busy hospital environments, where the demand for PET scans is high and resources are often limited.In summary, the ability to image multiple patients simultaneously with a single PET scanner offers advantages in terms of operational efficiency, reduced costs, and improved patient care. For example, the detection area per subject is approximately 35% of that of a conventional LAFOV PET scanner.

[0032] The examination area can be configured to accommodate at least two subjects simultaneously and / or the installation area can be configured to accommodate at least two subjects simultaneously, preferably placed side by side along the radial axis.

[0033] This PET device can be used in a horizontal configuration in which subjects are lying on the examination platform, or in a vertical configuration in which subjects are standing against the examination platform.

[0034] In an alternative configuration, subjects are positioned sitting or semi-sitting. This configuration is not possible with traditional PET scanners because they require a scanner for attenuation correction. This position is psychologically more comfortable for the subject, as lying down is associated with the illness psychologically. This configuration also allows for the rapid setup of several subjects simultaneously on a flat surface: in the case of three subjects, the middle subject must position themselves on the surface much like a person would lie down in bed from the foot of the bed (which is not always easy when space is limited and other subjects are already positioned to the side). It therefore reduces acquisition, setup, and removal time compared to the lying or standing positions.

[0035] The detection device is preferably of the long axial field of view (LAFOV) type. A LAFOV detector advantageously allows for imaging of a large portion of a subject's body, or even the entire body. An LAFOV detector offers a combination of sensitivity, resolution, and functionality that makes it a valuable tool for the diagnosis, monitoring, and treatment of various medical conditions. Its high spatial and temporal resolution enables the detection of even small abnormalities or changes in tissues. Thanks to its high sensitivity, the LAFOV detector can detect diseases at an early stage, allowing for rapid and often more effective medical intervention. It also allows for the use of lower radiation doses, minimizing risks to patients.

[0036] The detection device is preferably a pixelated or monolithic device using scintillation crystals, such as, for example, BGO (bismuth germanium oxide), LYSO (lutetium yttrium orthosilicate), or LSO (lutetium oxide orthosilicate), which convert the photons emitted by positrons into detectable electrical signals and possess depth of interaction (DOI) capabilities that allow them to maintain a resolution of 1.2 mm regardless of the angle of coincidence, unlike pixelated detector technology. These crystals are often coupled to photodetectors, such as photomultiplier tubes (PMTs) or photodiode detectors, which amplify the light signals produced by the scintillation crystals and convert them into electrical signals for further analysis.These detectors are positioned around the subject to record positron emissions and reconstruct three-dimensional images of the radiotracer distribution within the body. Preferably, the detection system incorporates silicon photomultiplier (SiPM) detectors, a type of light-sensitive photodetector used to detect photons emitted by scintillators. Advantageously, these photodetectors offer high sensitivity and low background noise, allowing for better differentiation between useful and unwanted signals, thus contributing to improved image quality and greater detection accuracy. They can cover a wide dynamic range, meaning they can detect signals ranging from low to high intensity levels.These detectors also offer the advantage of fast response times, enabling rapid PET data acquisition. This reduces the time required for image acquisition. Finally, they are generally compact and energy-efficient, making them suitable for use in high-throughput PET scanners and facilitating the use of detectors with very fast times of flight, on the order of 50 ps to 10 ps, ​​allowing for real-time imaging.

[0037] The detection device is configured to allow whole-body imaging and / or targeted organ imaging, also known as neurological or cardiac imaging. For example, the detection device may have two configurations: a whole-body imaging configuration and a neurological and / or cardiac imaging configuration. The detection device may be able to switch between these configurations, notably through rotation and movement. This advantageously doubles the number of subjects that can be scanned for organ imaging, whereas currently, the numerous detectors of whole-body PET scans are not used for neurological or cardiac imaging.

[0038] The detection device may include at least one inner wall (i.e., the wall closest to the subject in the examination area) and one outer wall.

[0039] The radiation detection device may include a PET detection ring. In a specific configuration, the detection ring may have a circular, elliptical, oval, polygonal, square, rectangular, or D-shaped geometry. In the case of a detection ring, the ring comprises an inner and an outer wall; the diameter defined by the inner wall is between 20 cm and 10 m, preferably between 30 cm and 5 m, and more preferably between 35 cm and 5 m. This advantageous geometry, positioned close to the patient's body, increases the number of photon pairs detected due to the increased angles of incidence. Advantageously, the use of a PET detection ring also allows for three-dimensional detection, i.e., the capture of signals emitted in all directions around the subject, thus enabling three-dimensional image reconstruction.This provides a comprehensive view of the radioactive tracer's distribution within the body, enabling a more precise assessment of metabolic activity. It also allows for the collection of more data in a single acquisition, resulting in shorter examination times and more efficient use of scan time. The detection ring's geometry enables precise image reconstruction, leading to more reliable and accurate results in terms of lesion localization and metabolic activity quantification. Finally, with a detection ring, subjects can be positioned in various ways while still ensuring complete image acquisition. This allows for better adaptation to the subject's specific needs or certain examination requirements.

[0040] According to an alternative illustrated in Figure 5, the radiation detection device can comprise two parallel plates arranged on either side of the examination platform and extending along the axial axis. In the case of two parallel plates, the detection device includes two inner walls, i.e., the faces of the two plates opposite each other, and two outer walls, i.e., the faces of the two plates opposite each other. The distance between two inner walls is between 20 cm and 1 m, preferably between 30 cm and 75 cm, and more preferably between 35 cm and 50 cm. Advantageously, the use of two parallel plates allows for high spatial resolution, leading to better visualization of small structures and more precise localization of metabolic activity within the body. Finally, this configuration allows for rapid patient setup with a single entry and exit point.

[0041] The detection device is sized to accommodate the number of subjects it is designed to scan. Its dimensions (radial, tangential, and axial) are adjustable according to the size of the examination platform, not the other way around. Therefore, the size of the detection device does not limit the number of subjects it can scan, as is the case with current devices. The detection device can have an axial length (length) between 50 cm and 3 m, preferably between 60 cm and 250 cm, and even more preferably between 70 cm and 220 cm. This size advantageously allows the detection device to have a sufficient axial length to generate tomography images of a part or the entire body of a subject.

[0042] The detection device can have a radial dimension (width) ranging from 50 cm to 10 m, preferably from 60 cm to 7.5 m, and even more preferably from 70 cm to 5 m. This dimension advantageously allows the detection device to be very wide along the radial axis, enabling the examination platform to accommodate several subjects in the examination area for simultaneous PET scans. This radial dimension range thus allows for the accommodation of numerous subjects with the aim of an optimal examination throughput. This radial dimension range is not simply an increase for the comfort of the subjects, but a real improvement aimed at increasing the number of subjects that can be examined in a short period of time. A conventional PET scanner, optimized for a single patient, has a much more limited radial dimension designed to maximize sensitivity for a single individual.The need for a width of 5 to 10 meters is not self-evident and directly addresses the objective of being able to position a large number of patients simultaneously, thus paving the way for mass screening applications. A person skilled in the art would likely have sought to miniaturize or optimize for a single patient, or to duplicate scanners, but not necessarily to create a single detection chamber of such magnitude for PET. A large radial dimension, for example close to 10 meters, advantageously allows for accommodating about ten subjects side-by-side simultaneously in the examination area and / or the setup area, thus enabling mass screening.

[0043] The detection device can have a tangential dimension (thickness) between 20 cm and 1 m, preferably between 30 cm and 75 cm, and more preferably between 35 cm and 50 cm. This tangential dimension allows the detection device to be positioned very close to the subject. This advantageous geometry, close to the patient's body, increases the number of photon pairs detected due to the increased angles of incidence. The dimension ranges above accommodate most templates down to 20 cm, preferably 35-40 cm to fit the thinnest templates.

[0044] This small tangential dimension advantageously allows the detection device to be kept extremely close to multiple subjects imaged simultaneously. This is a critical geometric constraint for PET technology, as detection sensitivity decreases rapidly with the subject-detection device distance. Achieving increased sensitivity (allowing a drastic dose reduction, on the order of 4 to 240 times) for ten patients simultaneously, for example, is an advantageous effect of the present invention.

[0045] The detection device may have a non-homogeneous dimension along the tangential axis; that is, there may be a thickness gradient along the radial axis, with the thickness at one radial end being less than at the other. Advantageously, this allows for different template sizes along the radial axis while maintaining an optimal subject-detector distance. This geometry is best suited to the morphology of subjects with personalized acolinearity. In comparison, and to a disadvantage, a conventional PET scanner, i.e., one that can only accommodate a single patient, must have a geometry designed to accommodate larger subjects, at the expense of geometry and therefore requiring a large number of detectors (suboptimal fixed acolinearity).

[0046] The combination of radial and tangential dimensions described above allows for increased large-scale multi-patient capacity while maintaining high sensitivity, thus reducing the injected dose to subjects. This is an optimized and non-obvious geometric design aimed at solving the problem of mass PET imaging with improved efficiency and safety.

[0047] The detection device may include an upper module for placement above the examination platform at the level of the examination area, a lower module for placement below the examination platform at the level of the examination area, and at least one lateral module, preferably two lateral modules, for placement on either side of the examination platform along the radial axis. The upper and lower modules are assembled with the lateral modules to form the detection device. The lateral modules may be symmetrical (promoting versatility) or asymmetrical (geometry adapted to the subjects' morphology with personalized acolinearity). Preferably, the lateral modules are asymmetrical.

[0048] In a configuration specific to a side module, the detection device therefore includes a lateral opening allowing a subject to pass into the examination area. The side modules can be fixed or removable. At least one side module can be a door with an associated actuator for opening and closing the detection device.

[0049] As illustrated in Figures 5-6, the radiation detection device may include at least one opening located at one end of the examination platform along the radial axis of the detection device, the opening being configured to allow a subject to position themselves in the setup area and / or the examination area. In the case of a vertically arranged PET scanner, this opening (or these openings) allows the subject to easily position themselves in the examination area.

[0050] The detection device can be moved along the axial axis, allowing it to be aligned alternately with the examination area and then the setup area. In this configuration, the examination platform does not move to accommodate the detection device. The roles of the examination and setup areas are therefore reversed by the movement of the detection device along the axial axis, while the examination platform retains both areas.

[0051] In this configuration, the examination platform preferably includes a fixed surface.

[0052] In a preferred configuration of this embodiment, the detection device may comprise two parallel plates arranged on either side of the examination platform and extending along the axial axis, each plate being movable along the axial axis. This configuration advantageously allows coverage of the different anatomical segments of the subject(s) in the examination area and / or enables the detection device to position itself at the level of the active examination area. If the detection device comprises a lower detection module and an upper detection module, both preferably in the form of plates: the lower detection module may be configured to move longitudinally under the examination platform; and / or the upper detection module may be configured to move longitudinally over the examination platform in the same longitudinal motion as the lower detection module.This can be achieved by installing rails fixed to the ceiling of the room in which the device is located, or by using a gantry structure resting on lateral rails integrated into the device.

[0053] The detection device may also include at least one lateral module that is also movable about the axial axis, capable of moving at the same speed, or faster, than the lower and upper modules.

[0054] The detection device can also be mobile along the axial axis and / or the radial axis and / or the tangential axis, capable of rotating 180° around any one of these axes. This allows for modification of the acquisition configuration. In other words, if the detection device comprises a plurality of modules (upper, lower, and / or lateral), at least one of these modules is then configured to rotate around the axial axis and / or the radial axis and / or the tangential axis, preferably through an angle between 0° and 180°, more preferably an angle of 180°.

[0055] Due to the use of a sliding platform and / or a mobile detection device along the axial axis, the setup area and the examination area can advantageously switch roles. In other words, once the imaging of the subject(s) in the examination area is complete, the platform can slide and / or the detection device can move along the axial axis, allowing the setup area to become an examination area, where the subjects previously positioned can now be imaged. The examination area and / or the setup area can have an axial dimension between 50 cm and 3 m, preferably between 60 cm and 250 cm, and more preferably between 70 cm and 220 cm.

[0056] The examination area and / or the installation area may have a dimension along the radial axis between 50 cm and 10 m, preferably between 60 cm and 7.5 m, more preferably between 70 cm and 5 m.

[0057] The examination area can have a dimension along the tangential axis ranging from 20 cm to 1 m, preferably between 30 cm and 75 cm, and more preferably between 35 cm and 50 cm. This dimension corresponds in particular to the distance between the examination platform and the detection device along the tangential axis. Advantageously, the subject is thus positioned directly at the required height for optimal detection by the detection device, also reducing acolinearity.

[0058] The examination platform may further include: a fixed support; a sliding platform arranged on the fixed support and comprising at least two sections arranged side by side along an axis of the detection device and configured to accommodate each one subject, at least one first section being arranged in the examination area and at least one second section being arranged in the installation area or in the examination area; a device for moving the sliding platform along an axis of the detection device configured to move at least one section from the installation area to the examination area.

[0059] This configuration of the examination platform advantageously allows two subjects to be accommodated simultaneously in the examination area or one subject in the examination area and one subject in the installation area.

[0060] The combination of accommodating two subjects simultaneously, one in the examination area and one in the installation area, with a platform including a multi-section sliding plan, advantageously allows for optimized management of waiting time before imaging and a large flow of subjects.

[0061] In the case of the simultaneous reception of two subjects in the examination area, it is advantageously possible to simultaneously generate tomography images of two subjects placed in an examination region.

[0062] In the case of simultaneous placement of one subject in the examination area and another in the setup area, it is advantageous to place one subject in the setup area and perform a PET scan on the other subject simultaneously. Here, one subject can be positioned while the previous one is being examined. Once the scan of the subject in the examination area is complete, the sliding platform is moved so that the subject previously in the setup area is transferred to the examination area for examination.

[0063] This configuration of the examination platform therefore allows a considerable time saving for the operator, and a time saving for a patient since, with the patient throughput increased in a given period, the waiting time for an imaging appointment will be shorter.

[0064] The fixed support may include a tabletop supported by four legs. For example, the fixed support is a table.

[0065] The sliding surface can be a carbon plate. Advantageously, carbon exhibits low photon attenuation while being rigid, and a carbon sliding surface will be lightweight and therefore easier to move.

[0066] The sliding plan can include partition elements to isolate sections (or reception areas). This isolation can be advantageously physical, in order to preserve the privacy of each individual seated in a section of the plan.

[0067] The partitioning elements may include vertical partitions, i.e., extending along the tangential axis. These may consist of a textile screen, for example, made of imitation leather, and cables attached to poles located at the cranial and caudal ends of each section, with the screen being secured to these cables. The partitioning elements may also include horizontal partitions, i.e., extending along the radial axis at the examination table level. These partitions are intended to visually delineate the examination and setup areas.

[0068] A section can have a dimension along the axial axis between 50 cm and 3 m, preferably between 60 cm and 250 cm, more preferably between 70 cm and 220 cm.

[0069] A section can have a dimension along the radial axis between 40 cm and 70 cm.

[0070] The device for moving the sliding plane can be a rail.

[0071] The sliding plane movement device can also be configured to allow movement of the sliding plane along the radial axis, preferably by about 60 cm, to facilitate access and installation / reinstallation of subjects to be imaged.

[0072] As illustrated in Figure 3, the at least two sections can be arranged side by side along the radial axis of the detection device, and the sliding plane movement device is configured to move the sliding plane along the axial axis of the detection device so that the examination platform is configured to simultaneously accommodate at least two subjects in the examination area. Side-by-side sections along the radial axis of the detection device are defined as two adjacent sections along this radial axis, i.e., sharing their longest side along the axial axis. Such sections are referred to hereafter as "radial sections." Ideally, this configuration is used in the case of a horizontal floor examination platform, in which two subjects can each lie in a section, so as to be simultaneously positioned in the examination area.This configuration advantageously allows for the simultaneous generation of tomography images of two subjects positioned within the same examination area. This configuration results in considerable time savings for the operator, as subjects can be imaged two at a time, and for the patient, since the number of examinations is doubled, thus reducing the waiting time for an imaging appointment. As illustrated in Figures 1-3, the two or more sections can be positioned side-by-side along the axial axis of the detection device, and the sliding plane movement mechanism is configured to move the sliding plane along the axial axis of the detection device, so that the examination platform is configured to simultaneously accommodate one subject in the examination area and one subject in the setup area.Side-by-side sections along the axial axis of the detection device are defined as two adjacent sections along this axial axis, i.e., sharing their side along the radial axis. Such sections are referred to hereafter as "axial sections." Ideally, this configuration is used with a horizontal floor-mounted examination platform, in which two subjects can be positioned, each in a separate section, so that they are placed simultaneously on the platform, one subject in the examination area and the other in the setup area. This configuration advantageously allows for the simultaneous placement of one subject in the setup area and the PET scan of another subject. Such a configuration therefore results in considerable time savings for the operator. Indeed, in the case of a conventional PET scanner, the setup of a subject requires that the previous subject have vacated the space. Here, a subject can be positioned while the previous one is being examined.The removal and subsequent installation of a subject takes approximately 5-10 minutes, saving the operator valuable time. Once the scan of the subject in the examination area is complete, the sliding platform moves the subject from the installation area to the examination area for scanning. This also saves time for the patient, as this configuration allows for an increased number of examinations per day, thus reducing the wait time for an imaging appointment.

[0073] The at least two sections can be arranged side by side along the radial axis of the detection device, and the sliding plane movement device is configured to move the sliding plane along the radial axis of the detection device, so that the examination platform is configured to simultaneously accommodate at least two subjects in the examination area or to simultaneously accommodate one subject in the examination area and one subject in the setup area. Side-by-side sections along the radial axis of the detection device are defined as two adjacent sections along this radial axis, i.e., sharing their side along the axial axis. Such sections are hereinafter referred to as "radial sections."Ideally, this configuration is used with an examination platform perpendicular to the floor, allowing two subjects to stand in separate sections so they can be positioned simultaneously on the platform. One subject can be in the examination area and the other in the setup area, or both subjects can be in the examination area simultaneously. This configuration allows for the simultaneous setup of one subject in the setup area and the PET scan of another subject. This results in considerable time savings for the operator. Indeed, with a conventional PET scanner, positioning a new subject requires the previous subject to have vacated the space. Here, a subject can be positioned while the previous one is being examined. Since positioning a new subject takes approximately 5-10 minutes, this translates into significant time savings for the operator.When the scan of the subject positioned in the examination area is complete, the sliding platform moves so that the subject previously in the setup area is moved to the examination area for scanning. This also saves time for the patient, as this configuration allows for an increased number of examinations per day, thus reducing the wait time for an imaging appointment. Alternatively, this configuration allows for the simultaneous generation of tomography images of two subjects positioned in the same examination area. This configuration therefore offers considerable time savings for the operator, as subjects can be imaged two at a time, and for the patient, since the number of examinations is doubled, resulting in a shorter wait time for an imaging appointment.

[0074] The examination platform may comprise at least two rows of at least two sections along an axis of the detection device, preferably along the radial or axial axis of the detection device. Advantageously, this configuration allows for the simultaneous installation of several subjects and / or the performance of simultaneous PET scans on multiple subjects.

[0075] Alternatively, the examination platform may include a fixed support comprising at least two sections arranged side by side along an axis of the detection device and configured to accommodate each one subject, at least a first section being arranged in the examination area and at least a second section being arranged in the installation area or in the examination area.

[0076] The examination tray can be mistaken for the internal wall of the detection device.

[0077] In this configuration, the examination platform does not include a sliding surface; the subjects move themselves within the examination area.

[0078] As illustrated in Figures 4-6, the at least two sections can be arranged side by side along the radial axis of the detection device, and the sliding plane movement device is configured to move the sliding plane along the radial axis of the detection device, so that the examination platform is configured to simultaneously accommodate at least two subjects in the examination area or to simultaneously accommodate one subject in the examination area and one subject in the setup area. Side-by-side sections along the radial axis of the detection device are defined as two adjacent sections along this radial axis, i.e., sharing their side along the axial axis. Such sections are hereinafter referred to as "radial sections."Ideally, this configuration is used with an examination platform perpendicular to the floor, allowing two subjects to stand in separate sections so they can be positioned simultaneously on the platform. One subject can be in the examination area and the other in the setup area, or both subjects can be in the examination area simultaneously. This configuration advantageously allows for one subject to be positioned in the setup area while another subject undergoes a PET scan simultaneously. Alternatively, this configuration also allows for the simultaneous generation of tomography images of two subjects positioned in the same examination region. Such a configuration therefore offers considerable time savings for the operator, as the subjects can be imaged two at a time.This also represents a time saving for a patient since it will be possible, with this configuration, to increase the number of examinations per day, the waiting time for an imaging appointment will therefore be shorter.

[0079] The examination platform is configured to accommodate at least two subjects, for example, between 2 and 20 subjects, preferably between 2 and 12 subjects. As illustrated in Figure 3, the PET scanner can include at least two examination platforms arranged side-by-side along the radial axis of the detector. This allows for the adjustment of the number of radial and / or axial sections according to needs or the available space in the PET scanner's installation area. It is therefore possible to increase the number of sections available in the installation area and / or the examination area. This configuration thus allows for the simultaneous installation of several subjects and / or the performance of simultaneous PET scans on multiple subjects. This configuration also allows for significant modularity of the PET scanner according to needs and the possibility of its future development (increasing or decreasing the number of platforms over time).

[0080] Alternatively, as illustrated in Figures 2 and 4-6, the PET scanner may consist of a single examination platform comprising at least two subject reception sections. This "monoblock" or "single-platform" configuration advantageously allows for the simultaneous installation of multiple subjects and / or the performance of simultaneous PET scans on multiple subjects.

[0081] The examination platform may include a jack configured to elevate a subject. This is particularly advantageous in the vertical configuration of the PET scanner, as it becomes possible to elevate one or more subjects depending on the area of ​​the body of interest, for example, for leg imaging. This jack can be combined with a seat and / or headrest, allowing each subject to be centered in relation to the detector.

[0082] The image generation device is an image generation device configured to collect the signal by photoelectric effect, Compton effect or other effect known in the field of PET imaging.

[0083] The image generation device is configured to generate three-dimensional (3D), four-dimensional (4D), five-dimensional (5D) or six-dimensional (6D) images from signals detected by the detection device in the examination region.

[0084] In medical imaging, a 4D image is a three-dimensional (3D) representation that evolves over time (fourth dimension). Unlike a static image, which captures a snapshot, a 4D image allows visualization of a phenomenon or process in motion or changing over time. In Positron Emission Tomography (PET), for example, a 4D image can be used to observe the distribution and elimination of a radiotracer in the body over time after its injection. This capability allows for the dynamic study of the kinetics of a radiotracer in different organs or tissues, thus providing valuable information on metabolic processes, tissue perfusion, or organ function.

[0085] In medical imaging, a 5D image is a multidimensional representation that includes not only the three spatial dimensions (length, width, and depth) but also a temporal dimension (fourth dimension) and another additional dimension. This additional dimension can vary depending on the context and type of imaging, but it may include parameters such as heart rate, contrast variation, or other physiological or functional data. Acquiring 5D images can allow for a more complete and dynamic visualization of biological processes, anatomical changes, and responses to treatments.

[0086] In medical imaging, a 6D image comprises six dimensions, typically the three spatial dimensions (length, width, depth) plus three additional dimensions. These extra dimensions can represent temporal variations, functional data, physiological data, or other specific characteristics of the observed phenomenon. A 6D image thus integrates spatial, temporal, and functional information to provide an even more complete and detailed representation of an anatomical structure, biological process, or physiological function.

[0087] The image generation device can be configured to simultaneously generate tomography images of at least two subjects placed in an examination area.

[0088] The image generation device may further include: an image generation means for generating images from signals detected by the detection ring in the examination region; a tomography image generation means configured to reconstruct a series of tomoscintigraphic images, so as to generate tomography images of subjects placed in the examination region.

[0089] The CT scanner may also include a subject identification system, such as a QR code reader, preferably positioned at the top of each scan section, or a facial recognition system. This reader scans the subject's unique identifier (for example, from a wristband or card) and automatically associates it with the acquisition data and the physical position occupied during the examination, thus minimizing the risk of error and optimizing workflow. This effectively ensures reliable identification and rigorous traceability of the subject in relation to their specific position within the scanner.

[0090] The present invention also relates to a method for generating tomography images of at least one subject placed in an examination area, comprising providing a positron emission tomography apparatus according to the invention; installing at least one subject in the examination area of ​​the examination platform; and generating tomography images of at least one subject placed in the examination area.

[0091] In this method, two subjects can be simultaneously placed in the PET scanner: a first subject in the examination area and a second subject in the installation area, or two subjects in the examination area.

[0092] Advantageously, this method optimizes resource utilization by efficiently sharing available time and equipment to perform parallel PET scans, while ensuring accurate and reliable data acquisition for each subject.

[0093] In the case of a first subject in the examination area and a second subject in the installation area, the method may include simultaneously, at the step of generating tomography images of the first subject, the installation of the second subject in the installation area.

[0094] In the case of a first subject in the examination area and a second subject in the setup area, the method may include, following the tomography image generation step of the first subject, moving the second subject into the examination area and then generating tomography images of the second subject. This subject movement can be performed by moving the sliding plane and / or the detection device along the axial axis. The areas are thus reversed.

[0095] The present invention also relates to a method for simultaneously generating tomography images of at least two subjects placed in an examination region, comprising: providing a positron emission tomography apparatus according to the invention; simultaneous generation of tomography images of the subjects placed in the examination region.

[0096] Advantageously, this method optimizes resource utilization by efficiently sharing available time and equipment to perform parallel PET scans, while ensuring accurate and reliable data acquisition for each subject.

[0097] BRIEF DESCRIPTION OF THE FIGURES

[0098] Ligure 1 illustrates an examination platform 12 according to an embodiment of the invention.

[0099] Ligure 2 illustrates a PET 1 device according to a first embodiment of the invention.

[0100] Ligure 3 illustrates a PET 1 device according to a second embodiment of the invention.

[0101] Ligure 4 illustrates a PET 1 device according to a third embodiment of the invention.

[0102] Figure 5 illustrates a PET scanner 1 according to a fourth embodiment of the invention.

[0103] Figure 6 illustrates a PET device 1 according to a fifth embodiment of the invention.

[0104] Figure 7 illustrates a PET device 1 according to a sixth embodiment of the invention.

[0105] Figure 8 illustrates a PET device 1 according to a seventh embodiment of the invention.

[0106] Figure 9 illustrates a PET device 1 according to an eighth embodiment of the invention.

[0107] ILLUSTRATIVE METHODS OF IMPLEMENTING THE INVENTION

[0108] In an embodiment illustrated in Figure 1, the examination platform 12 comprises: an examination area 121 opposite the examination region; an installation area 122 extending outside the examination region; a fixed support 123; a sliding platform 124 disposed on the fixed support and comprising two sections 125 arranged side by side along the axial axis z of the detection device and configured to accommodate each one subject, a first section 125 being disposed in the examination area 121 and a second section 125 being disposed in the installation area 122.

[0109] In a first embodiment illustrated in Figure 2, the PET scanner 1 comprises: a radiation detection device 11, in the form of a ring, arranged to visualize the examination region and comprising an axial axis z passing longitudinally through the center of the detection device 11, a radial axis x perpendicular to the axial axis z, and a tangential axis y perpendicular to both the axial axis z and the radial axis x; an examination platform 12 extending along the axial axis z and within the detection device 11, the examination platform 12 comprising:

[0110] ■ an examination area 121 opposite the examination region;

[0111] ■ an installation area 122 extending outside the examination area;

[0112] ■ a fixed support 123; ■ a sliding plan 124 arranged on the fixed support and comprising two sections 125 arranged side by side along the axial axis z of the detection device and configured to accommodate each one subject, a first section 125 being arranged in the examination area 121 and a second section 125 being arranged in the installation area 122.

[0113] These two embodiments are particularly advantageous because they allow for the simultaneous placement of one subject in the examination area 121 and another in the setup area 122. It is therefore possible to position one subject in the setup area 121 and perform a PET scan on another subject simultaneously. Here, one subject can be positioned while the previous one is being examined. When the scan of the subject in the examination area 121 is complete, the sliding platform 124 is moved so that the subject previously positioned in the setup area 122 is moved into the examination area 121 for examination. This results in considerable time savings for both the operator and the patients.

[0114] In a second embodiment illustrated in Figure 3, the PET device 1 comprises: a radiation detection device 11, in the form of a ring, arranged to visualize the examination region and comprising an axial axis z passing longitudinally through the center of the detection device 11, a radial axis x perpendicular to the axial axis z, and a tangential axis y perpendicular to both the axial axis z and the radial axis x; six examination platforms 12 extending along the axial axis z and within the detection device 11, each examination platform 12 comprising:

[0115] ■ an examination area 121 opposite the examination region;

[0116] ■ an installation area 122 extending outside the examination area;

[0117] ■ a fixed support 123;

[0118] ■ a sliding plan 124 arranged on the fixed support and comprising two sections 125 arranged side by side along the axial axis z of the detection device and configured to accommodate each one subject, a first section 125 being arranged in the examination area 121 and a second section 125 being arranged in the installation area 122.

[0119] The six examination platforms 12 arranged side by side along the radial axis x of the detection device 11. The PET device 1 therefore comprises six radial sections 125 that can accommodate a total of six patients in the installation area 122 and six radial sections 125 that can accommodate a total of six patients in the examination area 122.

[0120] This embodiment is particularly advantageous because it allows for the simultaneous placement of six subjects in the examination area 121 and six subjects in the setup area 122. It is therefore possible to position six subjects in setup area 121 and perform PET scans on six other subjects simultaneously. This results in considerable time savings for both the operator and the patients, as the scanning time and setup time are combined. Indeed, tomographic images can be generated simultaneously for six patients during an acquisition time equivalent to that of a single PET scan, and six patients can be positioned while six patients are being examined.For comparison, a conventional LAFOV PET scanner requires six minutes of setup and three minutes of CT scanning for five minutes of acquisition per patient, i.e. 2h48min for 12 patients, whereas with the PET 1 device according to this method of implementation, it will take less than 20 minutes to perform the scans of the 12 patients.

[0121] In a third embodiment illustrated in Figure 4, the PET scanner 1, in a vertical configuration, comprises: a radiation detection device 11, arranged to visualize the examination region and comprising an axial axis z running longitudinally through the center of the detection device 11, a radial axis x perpendicular to the axial axis z, and a tangential axis y perpendicular to both the axial axis z and the radial axis x; the detection device 11 comprising an upper module 111, a lower module 112, and two lateral modules 113 which, when assembled, form the detection device 11; an examination platform 12 extending along the axial axis z and within the detection device 11; the examination platform 12 comprising:

[0122] ■ an examination area 121 opposite the examination region;

[0123] ■ a fixed support 123 comprising five sections 125 arranged side by side along the radial x axis and configured to accommodate each one subject, the sections 125 being arranged in the examination area 121.

[0124] In this case, the examination platform is confused with the internal wall of the lower module 112.

[0125] In a fourth embodiment illustrated in Figure 5, the PET scanner 1, in a vertical configuration, comprises: a radiation detection device 11, arranged to visualize the examination region and comprising an axial axis z passing longitudinally through the center of the detection device 11, a radial axis x perpendicular to the axial axis z, and a tangential axis y perpendicular to both the axial axis z and the radial axis x; the detection device 11 comprising two parallel detection plates 114; an examination platform 12 extending along the axial axis z and within the detection device 11; the examination platform 12 comprising:

[0126] ■ an examination area 121 opposite the examination region;

[0127] ■ a fixed support 123 comprising five sections 125 arranged side by side along the radial x axis and configured to accommodate each one subject, the sections 125 being arranged in the examination area 121.

[0128] In this case, the examination platform is confused with the inner wall of a detection plate 114.

[0129] In a fifth embodiment illustrated in Figure 6, the PET scanner 1, in a vertical configuration, comprises: a radiation detection device 11, arranged to visualize the examination region and comprising an axial axis z running longitudinally through the center of the detection device 11, a radial axis x perpendicular to the axial axis z, and a tangential axis y perpendicular to both the axial axis z and the radial axis x; the detection device 11 comprising an upper module 111, a lower module 112, and a lateral module 113, which together form the detection device 11; an examination platform 12 extending along the axial axis z and within the detection device 11; the examination platform 12 comprising:

[0130] ■ an examination area 121 opposite the examination region;

[0131] ■ a fixed support 123 comprising five sections 125 arranged side by side along the radial x axis and configured to accommodate each one subject, the sections 125 being arranged in the examination area 121.

[0132] In this case, the examination platform is confused with the internal wall of the lower module 112.

[0133] In a sixth embodiment illustrated in Figure 7, the PET scanner 1, in a vertical configuration, comprises: a radiation detection device 11, arranged to visualize the examination region and comprising an axial axis z extending longitudinally through the center of the detection device 11, a radial axis x perpendicular to the axial axis z, and a tangential axis y perpendicular to both the axial axis z and the radial axis x; the detection device 11 comprising an upper module 111, a lower module 112, and a lateral module 113, which together form the detection device 11; two examination platforms 12 extending along the axial axis z and within the detection device 11; the examination platform 12, each comprising:

[0134] ■ an examination area 121 opposite the examination region;

[0135] ■ a fixed vertical support 123 comprising six sections 125 (delimited by dotted lines in the figure) arranged side by side along the radial axis x and configured to accommodate each one subject, the sections 125 being arranged in the examination area 121; ■ a horizontal sliding plane 124 configured to move along the tangential axis y;

[0136] ■ each section 125 being equipped with a device for maintaining the patient in a semi-sitting position 127 equipped with a jack 128, a head support device 129 and a wrist support device (not shown).

[0137] In this particular embodiment, the detection device therefore includes a lateral opening allowing for the rapid passage and positioning of patients. The patient restraint devices (127, 128, 129) allow for precise positioning of patients relative to the radiation detection device 11 (centered, at the correct height) and ensure their immobility throughout the scan.

[0138] These vertical configurations are particularly advantageous because they allow for the simultaneous acquisition and generation of tomographic images for five subjects. This results in considerable time savings for both the operator and the patients, as the scanning time is shared.

[0139] In a seventh embodiment illustrated in Figure 8, the PET scanner 1 comprises: a radiation detection device 11 arranged to visualize the examination area and comprising an axial axis z extending longitudinally through the center of the detection device 11, a radial axis x perpendicular to the axial axis z, and a tangential axis y perpendicular to both the axial axis z and the radial axis x; the detection device 11 comprising an upper module 111, a lower module 112, and a lateral module 113 which, when assembled, form the detection device 11; and an examination platform 12 extending along the axial axis z and within the detection device 11; the examination platform 12 comprising

[0140] ■ an examination area 121 opposite the examination region configured to accommodate at least 2 subjects simultaneously;

[0141] ■ an installation area 122 configured to accommodate at least 2 subjects simultaneously; separation elements 130 arranged between each section accommodating a subject.

[0142] This embodiment represents a wide field PET scan and advantageously allows two subjects to be scanned simultaneously (e.g., cancer screening covering from head to mid-thigh) and accommodates four subjects in total.

[0143] The radiation detection device 11 is advantageously mobile, with the upper and lower modules (111, 112) able to move along the examination platform, thus allowing the examination and installation areas (121, 122) to be interchanged. Illustrated here is an example of the upper modules 111 being mobile; they are fixed to a plate configured to slide in a groove cut into two lateral panels.

[0144] In installation area 122, subjects who have finished their exams uninstall themselves (this area was previously the imaging area), then new subjects install themselves.

[0145] In the examination area 121, subjects receive whole-body imaging. The upper modules 111 move along the longitudinal axis from the previous area to this area and then adjust as close as possible to the subject. The lateral modules 113 also move along the longitudinal axis from the previous area to this area and then adjust as close as possible to the subject. In this configuration, on the outer side of the device facing the subject, there is a lateral module 113 to maintain the sensitivity of device 1 on the outer side of the subject; on the inner side of the device facing the subject, the detection sensitivity is ensured by the lateral module 113 of the second subject (detector sharing). The lower modules 112, of comparable size to the upper detectors 111, move as close as possible to the examination platform 12.

[0146] The subjects are separated by a thin partition (130) that absorbs few photons, thus preserving a degree of privacy. There is also a partition (130) separating the two areas at the patients' feet.

[0147] In an eighth embodiment illustrated in Figure 9, the PET device 1 comprises: a radiation detection device 11 arranged to visualize the examination area and comprising an axial axis z extending longitudinally through the center of the detection device 11, a radial axis x perpendicular to the axial axis z, and a tangential axis y perpendicular to both the axial axis z and the radial axis x; the detection device 11 comprising an upper module 111, a lower module 112, and a lateral module 113 which, assembled, form the detection device 11; and an examination platform 12 extending along the axial axis z and within the detection device 11; the examination platform 12 comprising

[0148] ■ an examination area 121 opposite the examination region configured to accommodate at least 2 subjects simultaneously;

[0149] ■ an installation zone 122 configured to accommodate at least 2 subjects simultaneously;

[0150] ■ 130 separation elements arranged between each section accommodating a subject.

[0151] This embodiment represents a small field PET scan and advantageously allows four subjects to be scanned simultaneously in a manner centered on the anatomical area to be studied (e.g. cardiac or neurological imaging) and to accommodate eight subjects in total.

[0152] The large detectors have rotated 180°, with each detector now covering two subjects.

[0153] In setup area 122, subjects who have finished their examinations unpack (this area was previously the imaging area), and then new subjects are set up. The tables slide radially to facilitate the setup and unpacking of subjects, then move closer together before becoming the imaging area.

[0154] In examination zone 121, subjects benefit from dedicated anatomical imaging (here, cardiac examination). The upper modules 111 move along the longitudinal axis from the previous zone to this zone and then adjust as close as possible to the subject. The lateral modules 113 move along the longitudinal axis from the previous zone to this zone and then adjust as close as possible to the subject. In this solution, to the left of patient 1 (on the left), there is a lateral detector to maintain the system's sensitivity on the patient's left side; to their right, detection sensitivity is ensured by patient 2's detector (detector sharing). The lower detectors, of comparable size to the upper detectors, move as close as possible to the thin carbon table.In this configuration, on the external side of the device facing the subject, there is a lateral module 113 to maintain the sensitivity of device 1 on the external side of the subject; on the internal side of the device facing the subject, detection sensitivity is ensured by the lateral module 113 of the second subject (shared detectors). The lower modules 112, of comparable size to the upper detectors 111, move as close as possible to the examination platform 12.

[0155] The subjects are separated by a thin partition (130) that absorbs few photons, thus preserving a degree of privacy. There is also a partition (130) separating the two areas at the patients' feet.

[0156] NUMERICAL REFERENCES

[0157] 1 - Positron Emission Tomography Unit / / 11 - Radiation Detection Device II 111 - Upper Module / / 112 - Lower Module / / 113 - Lateral Module / / 114 - Detection Plates / / Z - Axial Axis II X - Radial Axis / / Y - Tangential Axis II 12 - Examination Platform / / 121 - Examination Area / / 122 - Installation Area / / 123 - Fixed Support / / 124 - Sliding Plane / / 125 - Section / / 126 - Sliding Plane Movement Device / / 127 - Patient Holding Device in Semi-Sitting Position / / 128 - Jack / / 129 - Head Holding Device / / 130 - Separating Element

Claims

1. DEMANDS 1. A positron emission tomography device (1) configured to generate tomography images of at least one subject placed in an examination region, the device (1) comprising: a radiation detection device (11) arranged to view the examination region and comprising an axial axis (z) longitudinally passing through the center of the detection device (11), a radial axis (x) perpendicular to the axial axis (z) and a tangential axis (y) perpendicular to both the axial axis (z) and the radial axis (x); an examination platform (12) extending along the axial axis (z) and inside the detection device (11), the examination platform (12) comprising an examination area (121) opposite the examination region and an installation area (122) extending outside the examination region, the examination platform (12) being configured to simultaneously accommodate at least two subjects, of which at least one subject is in the examination area (121);an image generation device for generating 3D or 4D images from signals detected by the detection device (11) in the examination region.; 2. Positron emission tomography apparatus (1) according to claim 1, wherein the detection device (11) is movable along the axial axis (z).

3. Positron emission tomography apparatus (1) according to claim 2, wherein the detection device (11) is configured to perform a rotation about the axial axis (z) through an angle between 0° and 180°, preferably an angle of 180°.

4. Positron emission tomography apparatus (1) according to any one of claims 2 to 3, wherein the examination platform (12) further comprises: a fixed support (123); a sliding plane (124) disposed on the fixed support (123) and comprising at least two sections (125) arranged side by side along an axis of the detection device (x, y, z) and configured to accommodate each a subject, at least a first section (125) being disposed in the examination area (121) and at least a second section (125) being disposed in the installation area (122) or in the examination area (121); a sliding plane displacement device (124) along an axis of the detection device (x, y, z) configured to move at least one section (125) from the installation area (122) to the examination area (121).

5. Positron emission tomography apparatus (1) according to claim 4, wherein the at least two sections (125) are arranged side by side along the radial axis of the detection device (x), and the sliding plane displacement device (124) is configured to move the sliding plane (124) along the axial axis of the detection device (z) so that the examination tray (12) is configured to simultaneously accommodate at least two subjects in the examination region.

6. Positron emission tomography apparatus (1) according to any one of claims 4 to 5, wherein the at least two sections (125) are arranged side by side along the axial axis of the detection device (z), and the sliding plane displacement device (124) is configured to move the sliding plane (124) along the axial axis of the detection device (z), so that the examination tray (12) is configured to simultaneously accommodate a subject in the examination region and a subject in the setup area (122).

7. Positron emission tomography apparatus (1) according to any one of claims 4 to 6, wherein the at least two sections (125) are arranged side by side along the radial axis of the detection device (x), and the sliding plane displacement device (124) is configured to move the sliding plane (124) along the radial axis of the detection device (x), so that the examination tray (12) is configured to simultaneously accommodate at least two subjects in the examination region or simultaneously accommodate one subject in the examination region and one subject in the setup area (122).

8. Positron emission tomography apparatus (1) according to any one of claims 1 to 7, wherein the examination platform (12) comprises at least two rows of at least two sections (125) along an axis of the detection device (x, y, z), preferably along the radial axis (x) or the axial axis (z) of the detection device (11).

9. Positron emission tomography apparatus (1) according to any one of claims 1 to 8, comprising at least two examination platforms (12) arranged side by side along the radial axis of the detection device (x).

10. Positron emission tomography apparatus (1) according to any one of claims 1 to 3, wherein the examination platform (12) further comprises a fixed support (123) comprising at least two sections (125) arranged side by side along an axis of the detection device (x, y, z) and configured to accommodate each one subject, at least a first section (125) being disposed in the examination area (121) and at least a second section (125) being disposed in the installation area (122) or in the examination area (121).

11. Positron emission tomography apparatus (1) according to any one of claims 1 to 10, configured to accommodate a subject in a supine or standing position.

12. Positron emission tomography apparatus (1) according to any one of claims 1 to 11, configured to accommodate a subject in a seated or semi-seated position.

13. Positron emission tomography apparatus (1) according to any one of claims 1 to 12, wherein the detection device (11) has a dimension along the axial axis (z) of between 50 cm and 3 m.

14. Positron emission tomography apparatus (1) according to any one of claims 1 to 13, wherein the detection device (11) has a dimension along the radial axis (x) between 50 cm and 10 m.

15. Positron emission tomography apparatus (1) according to any one of claims 1 to 14, wherein the detection device (11) has a dimension along the tangential axis (y) of between 20 cm and 1 m.

16. Positron emission tomography apparatus (1) according to any one of claims 1 to 15, further comprising a subject identification system.

17. Positron emission tomography apparatus (1) according to any one of claims 1 to 16, wherein the examination platform (12) is configured to simultaneously accommodate at least four subjects, of which at least two subjects are in the examination area (121).

18. Method for generating tomography images of at least one subject placed in an examination region of a positron emission tomography device (1), said method comprising: supplying a positron emission tomography device (1) according to any one of claims 1 to 17; installing at least two subjects, at least one of whom is in the examination area (121); generating tomography images of at least one subject placed in the examination region.

19. Method according to claim 18 comprising: a step of moving at least one subject from the installation area (122) to the examination area (121); generation of tomography images of the subject moved in the examination area (121).

20. Method according to claim 19, wherein the movement of the subject from the installation area (122) to the examination area (121) is carried out by the movement of the sliding plane (124) and / or the detection device (11) along the axial axis (x).

Images