Skin regeneration patch assembly and manufacturing method therefor

Abstract

A skin regeneration patch assembly is disclosed. The skin regeneration patch assembly according to one embodiment of the present invention comprises: a patch support including a patch support sheet, which has a sheet-shaped patch support sheet body, and a sheet-shaped patch knob, which is detachably coupled to the patch support sheet body; and a skin regeneration patch, which is detachably coupled to the patch knob and is detachably coupled to the patch support sheet, wherein the skin regeneration patch can include: a skin regeneration patch sheet having a lower surface, which is detachably coupled to the upper surface of the patch support sheet body and the upper surface of the patch knob; and a skin regeneration patch core, which is coupled to the lower surface of the skin regeneration patch sheet and is positioned in front of the patch knob.

Description

Skin regeneration patch assembly and method of manufacturing the same

[0001] The present invention relates to a skin regeneration patch assembly and a method for manufacturing the same.

[0002] A skin regeneration patch that promotes skin regeneration by attaching it to a user's affected area may take the form of a sheet or a film. The thinner the skin regeneration patch, the greater the user's convenience. In order for the skin regeneration patch to be used conveniently, the structure of the skin regeneration patch needs to be improved.

[0003] The convenience of the user of the skin regeneration patch may include, for example, the adhesive strength with which the skin regeneration patch adheres to the affected area, the cosmetic effect when the skin regeneration patch is adhered to the affected area, and the degree to which the skin regeneration patch adheres to the affected area when the affected area has a curved shape.

[0004] (Patent Document 1) KR 10-1241752 B1

[0005] The present invention aims to solve the aforementioned problems and other problems.

[0006] The present invention has another objective of providing a skin regeneration patch assembly comprising a thin skin regeneration patch and a method for manufacturing the same.

[0007] The present invention has another objective of providing a skin regeneration patch assembly that does not absorb exudate generated from the skin and a method for manufacturing the same.

[0008] According to one aspect of the present invention, a skin regeneration patch assembly may be provided, comprising: a patch support sheet having a sheet-shaped patch support sheet body and a sheet-shaped patch knob detachably coupled to the patch support sheet body; a skin regeneration patch detachably coupled to the patch knob and detachably coupled to the patch support sheet, wherein the skin regeneration patch comprises: a skin regeneration patch sheet having a lower surface detachably coupled to the upper surface of the patch support sheet body and the upper surface of the patch knob; and a skin regeneration patch core coupled to the lower surface of the skin regeneration patch sheet and positioned in front of the patch knob.

[0009] The patch support sheet may include a patch support knob opening, which is an opening formed in the patch support sheet body and where the patch knob is located.

[0010] The patch support sheet may include a patch support core opening, which is an opening formed in the patch support sheet body and in which the skin regeneration patch core is located.

[0011] The patch support core opening and the patch support knob opening can be connected to each other.

[0012] The patch support core opening may be located in front of the patch support knob opening.

[0013] The patch support sheet includes a patch support knob opening formed in the patch support sheet body, wherein the skin regeneration patch core is located therein, and the patch knob may be located in front of the patch support knob opening.

[0014] The rear end of the patch knob may be formed along a part of the patch support knob opening.

[0015] The patch support sheet body may include a patch attachment portion formed along the patch support knob opening and to which the skin regeneration patch sheet is attached.

[0016] The skin regeneration patch sheet may include: a skin regeneration patch sheet support area coupled to the patch attachment portion; a skin regeneration patch sheet core area coupled to the skin regeneration patch core; and a skin regeneration patch sheet knob area detachably coupled to the patch knob.

[0017] The skin regeneration patch sheet support area and the skin regeneration patch sheet knob area can be arranged along the outer circumference of the skin regeneration patch sheet core area.

[0018] A plurality of grooves may be formed on the lower surface of the above-mentioned skin regeneration patch core.

[0019] Each of the above plurality of grooves can form a shape extended in the front-rear direction.

[0020] The above plurality of grooves can be arranged sequentially in the left and right directions.

[0021] The above plurality of grooves can form irregularities in the left and right directions.

[0022] According to one aspect of the present invention, a method for manufacturing a skin regeneration patch assembly may be provided, comprising the steps of: forming a patch support including a patch support sheet body and a patch support core opening formed in the patch support sheet body; attaching a skin regeneration patch sheet to the patch support sheet body; and coupling a skin regeneration patch core to the skin regeneration patch sheet.

[0023] The above skin regeneration patch core may be located in the opening of the patch support core.

[0024] In the step of forming the patch support, a patch knob may be detachably coupled to the patch support sheet body.

[0025] The area of ​​the skin regeneration patch sheet may include: a skin regeneration patch core area coupled to the skin regeneration patch core; a skin regeneration patch sheet support area coupled to the patch support sheet body; and a skin regeneration patch sheet knob area coupled to the patch knob.

[0026] According to at least one of the embodiments of the present invention, a skin regeneration patch assembly comprising a thin skin regeneration patch and a method for manufacturing the same may be provided.

[0027] According to at least one of the embodiments of the present invention, a skin regeneration patch assembly that does not absorb exudate generated from the skin and a method for manufacturing the same may be provided.

[0028] FIG. 1 is a drawing showing a patch support among a skin regeneration patch assembly according to one embodiment of the present invention.

[0029] FIG. 2 is a drawing showing a skin regeneration patch sheet of a skin regeneration patch according to one embodiment of the present invention.

[0030] Figure 3 is an exploded perspective view of a skin regeneration patch.

[0031] Figure 4 is a drawing showing the skin regeneration patch sheet and skin regeneration patch core shown in Figure 3 combined with each other.

[0032] Figure 5 is a cross-sectional view of the skin regeneration patch shown in Figure 4, cut along A1-A2.

[0033] Figure 6 is a cross-section of the skin regeneration patch shown in Figure 4, cut along B1-B2.

[0034] Figure 7 is a diagram showing the combined state of the patch support shown in Figure 1 and the skin regeneration patch shown in Figure 4.

[0035] FIG. 8 is a cross-sectional view of the skin regeneration patch assembly shown in FIG. 7, cut along C1-C2.

[0036] Figure 9 is a drawing showing the appearance of the patch support after removing the skin regeneration patch module from the skin regeneration patch assembly shown in Figure 7.

[0037] <National R&D Project that supported this invention 1>

[0038] Project ID: 1345370809

[0039] Project No.: 2021RIS-002

[0040] Ministry Name: Ministry of Education

[0041] Project Management (Specialized) Agency Name: National Research Foundation of Korea

[0042] Research Project Name: Local Government-University Cooperation-Based Regional Innovation Project

[0043] Research Project Title: (Gwangju-Jeonnam Regional Innovation Platform) Chonnam National University

[0044] Project Performing Organization Name: Chonnam National University

[0045] Research Period: May 1, 2024 – November 30, 2024

[0046] <National R&D Project that supported this invention 2>

[0047] Project ID: 1415190197

[0048] Project Number: IRGJ2210

[0049] Ministry Name: Ministry of Trade, Industry and Energy

[0050] Project Management (Specialized) Agency Name: Korea Industrial Complex Corporation

[0051] Research Project Name: Strengthening Competitiveness of Industrial Clusters (R&D)

[0052] Research Project Title: Development of Nanostructured Wound Dressings for Promoting Skin Regeneration and Industrial

[0053] Karma

[0054] Project Performing Organization Name: Nanobiosystem Co., Ltd.

[0055] Research Period: 2022.10.01 ~ 2024.03.31

[0056] Hereinafter, embodiments disclosed in this specification will be described in detail with reference to the attached drawings. Identical or similar components regardless of drawing symbols will be assigned the same reference number, and redundant descriptions thereof will be omitted. The suffixes "module" and "part" used for components in the following description are assigned or used interchangeably solely for the ease of drafting the specification and do not inherently possess distinct meanings or roles. Furthermore, in describing embodiments disclosed in this specification, if it is determined that a detailed description of related prior art could obscure the essence of the embodiments disclosed in this specification, such detailed description will be omitted. Additionally, the attached drawings are intended only to facilitate understanding of the embodiments disclosed in this specification; the technical concept disclosed in this specification is not limited by the attached drawings, and it should be understood that they include all modifications, equivalents, and substitutions that fall within the spirit and technical scope of the present invention.

[0057] Terms including ordinal numbers, such as first, second, etc., may be used to describe various components, but said components are not limited by said terms. These terms are used solely for the purpose of distinguishing one component from another.

[0058] When it is stated that one component is "connected" or "connected" to another component, it should be understood that while it may be directly connected or connected to that other component, there may also be other components in between. On the other hand, when it is stated that one component is "directly connected" or "directly connected" to another component, it should be understood that there are no other components in between.

[0059] A singular expression includes a plural expression unless the context clearly indicates otherwise.

[0060] In this application, terms such as “comprising” or “having” are intended to specify the existence of the features, numbers, steps, actions, components, parts, or combinations thereof described in the specification, and should be understood as not precluding the existence or addition of one or more other features, numbers, steps, actions, components, parts, or combinations thereof.

[0061] In the drawings, the size of components may be exaggerated or reduced for convenience of explanation. For example, the size and thickness of each component shown in the drawings are depicted arbitrarily for convenience of explanation, so the present invention is not necessarily limited to what is illustrated.

[0062] Where an embodiment can be implemented differently, a specific process sequence may be performed differently from the order described. For example, two processes described consecutively may be performed substantially simultaneously or proceed in the reverse order of the description.

[0063] In the following embodiments, when it is stated that a membrane, region, component, etc. is connected, it includes not only cases where the membrane, region, or component is directly connected, but also cases where other membranes, regions, or components are interposed between them to form an indirect connection. For example, when it is stated in this specification that a membrane, region, component, etc. is electrically connected, it includes not only cases where the membrane, region, or component, etc. are directly electrically connected, but also cases where other membranes, regions, or components are interposed between them to form an indirect electrical connection.

[0064] The XYZ coordinate system may be used in this specification. The XYZ coordinate system may be a Cartesian coordinate system. For example, the XYZ coordinate system may be a right-handed Cartesian coordinate system.

[0065] For example, the positive X-axis direction can be rearward. For example, the negative X-axis direction can be forward. For example, the positive Y-axis direction can be right-direction. For example, the negative Y-axis direction can be left-direction. For example, the positive Z-axis direction can be upward. For example, the negative Z-axis direction can be downward.

[0066] FIG. 1 is a drawing showing a patch support among a skin regeneration patch assembly according to one embodiment of the present invention.

[0067] The skin regeneration patch assembly (10) may include a patch support (100). The patch support (100) may include a patch support sheet (110). The patch support sheet body (111) may form the shape of a film or a sheet.

[0068] For example, the patch support sheet (110) can form two sides. For example, the patch support sheet (110) can form an upper face and a lower face.

[0069] The upper surface of the patch support sheet (110) may face upward. The lower surface of the patch support sheet (110) may face downward. The thickness of the patch support sheet (110) may be the distance between the upper surface and the lower surface of the patch support sheet (110).

[0070] The patch support sheet (110) may include a patch support sheet body (111) and a patch knob (112). The patch knob (112) may be detachably coupled to the patch support sheet body (111). For example, the patch support sheet body (111) and the patch support knob (112) may be formed by processing a single sheet.

[0071] The patch support (100) may include a patch support core opening (120). The patch support core opening (120) may be an opening formed in the patch support sheet (110).

[0072] For example, the patch support core opening (120) can penetrate the upper and lower surfaces of the patch support sheet (110). For example, the patch support core opening (120) can be connected to the upper and lower surfaces of the patch support sheet (110).

[0073] The patch support core opening (120) can be formed by the patch support sheet body (111) and the patch knob (112). For example, part of the boundary of the patch support sheet body (111) and part of the boundary of the patch knob (112) can form the perimeter of the patch support core opening (120).

[0074] For example, a portion of the perimeter of the patch support core opening (120) may be connected to the patch support sheet body (111). For example, another portion of the perimeter of the patch support core opening (120) may be connected to the pad knob (112).

[0075] The patch support sheet body (111) may be divided into multiple regions. For example, the patch support sheet body (111) may be divided into a patch attachment portion (111A) and a patch non-attachment portion (111N). The patch non-attachment portion (111N) may be the remaining region of the patch support sheet body (111) excluding the patch attachment portion (111A).

[0076] The patch attachment portion (111A) may be an area adjacent to the patch support core opening (120) within the area of ​​the patch support sheet body (111). For example, the patch attachment portion (111A) may extend along the patch support core opening (120) from one side of the patch knob (112) and connect to the other side of the patch knob (112).

[0077] FIG. 2 is a drawing showing a skin regeneration patch sheet of a skin regeneration patch according to one embodiment of the present invention.

[0078] Referring to FIG. 2, a skin regeneration patch assembly (10, see FIG. 7) may include a skin regeneration patch (200). The skin regeneration patch (200) may include a skin regeneration patch sheet (210).

[0079] The skin regeneration patch sheet (210) can form the shape of a film or a sheet. For example, the skin regeneration patch sheet (210) can form an upper surface and a lower surface. In FIG. 2, the lower surface of the skin regeneration patch sheet (210) can be observed. The skin regeneration patch sheet (210) can be divided into a plurality of regions.

[0080] For example, the skin regeneration patch sheet (210) may include a skin regeneration patch sheet core region (210C). The skin regeneration patch sheet core region (210C) may be spaced apart from the perimeter of the skin regeneration patch sheet (210). For example, the skin regeneration patch sheet core region (210C) may form the center of the skin regeneration patch sheet (210).

[0081] For example, the skin regeneration patch sheet (210) may include a skin regeneration patch sheet knob region (210K). The skin regeneration patch sheet knob region (210K) may extend from part of the boundary of the skin regeneration patch sheet core region and connect to part of the perimeter of the skin regeneration pitch sheet (210).

[0082] For example, the skin regeneration patch sheet knob area (210K) and the skin regeneration patch sheet core area (210C) can be arranged side by side. For example, the skin regeneration patch sheet knob area (210K) can be located behind the skin regeneration pitch sheet core area (210C).

[0083] For example, the skin regeneration patch sheet (210) may include a skin regeneration patch sheet support area (210A). The skin regeneration patch sheet support area (210A) may be the remaining area of ​​the skin regeneration patch sheet (210) excluding the skin regeneration patch sheet core area (210C) and the skin regeneration patch sheet knob area (210K).

[0084] FIG. 3 is an exploded perspective view of a skin regeneration patch. FIG. 4 is a drawing showing the skin regeneration patch sheet and the skin regeneration patch core shown in FIG. 3 combined with each other. FIG. 5 is a drawing showing a cross-section of the skin regeneration patch shown in FIG. 4 cut along A1-A2. FIG. 6 is a drawing showing a cross-section of the skin regeneration patch shown in FIG. 4 cut along B1-B2.

[0085] Referring to FIGS. 3 through 6, the skin regeneration patch (200) may include a skin regeneration patch core (220). The skin regeneration patch core (220) may form the shape of a film or a sheet. For example, the skin regeneration patch core (220) may form an upper surface and a lower surface.

[0086] The skin regeneration patch core (220) may contain ingredients necessary for skin regeneration. For example, the skin regeneration patch core (220) may contain a biocompatible polymer. For example, the skin regeneration patch core (220) may contain a polycaprolactone (PCL) component.

[0087] For example, the skin regeneration patch core (220) may include a poly-lactide-co-glycolide-acid (PLGA) component. For example, the skin regeneration patch core (220) may include a hydrocolloid.

[0088] For example, the skin regeneration patch core (220) may include a collagen component. For example, the skin regeneration patch core (220) may include porcine collagen. For example, the skin regeneration patch core (220) may include porcine collagen type 1.

[0089] For example, the skin regeneration patch core (220) may contain polylactic acid (PLA). For example, the skin regeneration patch core (220) may contain polypropylene lactic acid (PDLLA). For example, the skin regeneration patch core (220) may contain chitosan.

[0090] Biocompatible materials are exemplified as materials included in the skin regeneration patch core (220), but are not limited thereto.

[0091] Polycaprolactone and polylactide coglycolic acid may be hydrophobic. For example, polycaprolactone and polylactide coglycolic acid may not absorb exudates from the skin.

[0092] Exudate from the skin can aid in the healing of the affected area. Therefore, since the skin regeneration patch core (220) does not absorb the exudate, the treatment of the affected area can be performed more effectively.

[0093] Additionally, if the skin regeneration patch core (220) absorbs exudate, the skin regeneration patch core (220) may swell. By not absorbing exudate, the beauty effect felt by the user may be enhanced.

[0094] For example, the ingredients required for skin regeneration may form one side of the skin regeneration patch core (220). For example, the ingredients required for skin regeneration may form at least a portion of the lower surface of the skin regeneration patch core (220).

[0095] The skin regeneration patch core (220) can be combined with or attached to the skin regeneration patch sheet (210). For example, the upper surface of the skin regeneration patch core (220) can be combined with or attached to the lower surface of the skin regeneration patch sheet (210).

[0096] For example, the skin regeneration patch core (220) may be joined to or attached to the skin regeneration patch sheet core region (210C). For example, the upper surface of the skin regeneration patch core (220) may be joined to or attached to the lower surface of the skin regeneration patch sheet core region (210C).

[0097] The skin regeneration patch core (220) can be positioned parallel to the skin regeneration patch knob area (210K). For example, the skin regeneration patch core (220) can be positioned in front of the skin regeneration patch knob area (210K).

[0098] A pattern may be formed on one side of the skin regeneration patch core (220). For example, a pattern may be formed on the lower surface of the skin regeneration patch core (220). For example, the pattern formed on the skin regeneration patch core (220) may include a plurality of grooves.

[0099] Each of the plurality of grooves formed in the skin regeneration patch core (220) can form a shape that extends in one direction. For example, the extension direction of each of the plurality of grooves formed in the skin regeneration patch core (220) may be the direction in which the skin regeneration patch core (220) and the skin regeneration patch sheet knob area (210K) are positioned.

[0100] The direction in which the skin regeneration patch core (220) and the skin regeneration patch sheet knob area (210K) are positioned may be the length direction of the skin regeneration patch (200). For example, the width direction of the skin regeneration patch (200) may intersect with the length direction of the skin regeneration patch (200). For example, the width direction of the skin regeneration patch (200) may be parallel to the Y-axis direction. For example, the width direction of the skin regeneration patch (200) may be the left-right direction.

[0101] A plurality of grooves formed in the skin regeneration patch core (220) can form irregularities. For example, a plurality of grooves formed in the skin regeneration patch core (220) can form irregularities in the left-right direction.

[0102] For example, the extension direction of each of the plurality of grooves formed in the skin regeneration patch core (220) may be parallel to the front-rear direction. For example, the extension direction of each of the plurality of grooves formed in the skin regeneration patch core (220) may be parallel to the X-axis direction.

[0103] For example, a plurality of grooves formed in the skin regeneration patch core (220) may be arranged sequentially in the width direction of the skin regeneration patch (200). For example, a plurality of grooves formed in the skin regeneration patch core (220) may be arranged sequentially in the left-right direction.

[0104] FIG. 7 is a drawing showing the combined state of the patch support shown in FIG. 1 and the skin regeneration patch shown in FIG. 4. FIG. 8 is a drawing showing a cross-section of the skin regeneration patch assembly shown in FIG. 7 cut along C1-C2. FIG. 9 is a drawing showing the appearance of the patch support after removing the skin regeneration patch module from the skin regeneration patch assembly shown in FIG. 7.

[0105] Referring to FIGS. 7 through 9, the skin regeneration patch module (20) may include a skin regeneration patch (200) and a patch knob (112). The skin regeneration patch (200) and the patch knob (112) may be combined with each other.

[0106] For example, the skin regeneration patch sheet (210) and the patch knob (112) can be combined with each other. For example, the skin regeneration patch sheet knob area (210K) and the patch knob (112) can be detachably combined or attached to each other. For example, the lower surface of the skin regeneration patch sheet knob area (210K) and the upper surface of the patch knob (112) can be detachably combined or attached to each other.

[0107] The skin regeneration patch (200) and the patch support (100) can be combined with each other. For example, the skin regeneration patch sheet (210) and the patch attachment portion (111A) can be combined with each other. For example, the skin regeneration patch sheet support area (210A) and the patch attachment portion (111A) can be combined or attached with each other. For example, the lower surface of the skin regeneration patch sheet support area (210A) can be detachably combined or attached to the upper surface of the patch attachment portion (111A).

[0108] The skin regeneration patch module (20) can be separated from the patch support sheet body (111). For example, a user can separate the patch knob (112) from the patch non-attachment portion (111N) and hold it.

[0109] For example, the user can separate the skin regeneration patch module (20) from the patch support sheet body (111) by lifting the patch knob (112) while holding the patch knob (112).

[0110] Before the skin regeneration patch module (20) is separated from the patch support sheet body (111), the skin regeneration patch core (220) may be positioned in the patch support core opening (120, see FIG. 1).

[0111] When the skin regeneration patch module (20) is separated from the patch support sheet body (111), a patch support knob opening (130) may be formed in the patch support body (111). Before the patch knob (112) is separated from the patch non-attached portion (111N), the patch knob (112) may be positioned in the patch support knob opening (130).

[0112] The patch support knob opening (130) may be an opening formed in the patch support sheet body (111). The patch support knob opening (130) may be connected to or communicate with the patch support core opening (120).

[0113] For example, the user can apply the skin regeneration patch core (220) to the affected area while holding the patch knob (112). In this process, the skin regeneration patch sheet support area (210A) can be attached around the affected area.

[0114] The longitudinal direction of the skin regeneration patch (200) attached to the affected area may intersect with the direction of the incision of the affected area. For example, the longitudinal direction of each of the plurality of grooves formed in the skin regeneration patch core (220) may intersect with the direction of the incision of the affected area. By doing so, the incision portion of the affected area can be effectively regenerated.

[0115] For example, the user can detach the patch knob (112) from the skin regeneration patch (200). The skin regeneration patch sheet knob area (210K) detached from the patch knob (112) can be attached around the affected area.

[0116] Referring to FIGS. 1 to 9, a method for manufacturing a skin regeneration patch assembly (10) can be considered.

[0117] For example, a method for manufacturing a skin regeneration patch assembly (10) may include the step of forming a patch support (100). In this step, a patch support core opening (120) may be formed in a patch support sheet body (111). In this step, a patch knob (112) may be positioned in a patch support knob opening (130) and detachably coupled to the patch support sheet body (111).

[0118] For example, a method for manufacturing a skin regeneration patch assembly (10) may include the step of attaching a skin regeneration patch sheet (210) to a patch support (100). In this step, the skin regeneration patch sheet support area (210A) may be detachably attached to a patch attachment portion (111A). In this step, the skin regeneration patch sheet knob area (210K) may be detachably attached to a patch knob (112).

[0119] For example, a method for manufacturing a skin regeneration patch assembly (10) may include the step of combining a skin regeneration patch core (220) with a skin regeneration patch sheet (210). In this step, the skin regeneration patch core (220) may be combined, attached, or applied to a skin regeneration patch sheet core area (210C). In this step, the skin regeneration patch core (220) may be positioned in a patch support core opening (120).

[0120] Some or other embodiments of the present invention described above are not exclusive or distinct from one another. Some or other embodiments of the present invention described above may be used in combination or combined, with their respective components or functions.

[0121] It is obvious to those skilled in the art that the present invention may be embodied in other specific forms without departing from the spirit and essential features of the invention. The foregoing detailed description should not be interpreted restrictively in any respect and should be considered exemplary. The scope of the invention shall be determined by a reasonable interpretation of the appended claims, and all modifications within the equivalent scope of the invention are included within the scope of the invention.

Claims

1. A patch support sheet having a sheet-shaped patch support sheet body and a patch support including a sheet-shaped patch knob detachably coupled to the patch support sheet body; and A skin regeneration patch comprising a patch detachably coupled to the patch knob and detachably coupled to the patch support sheet, The above skin regeneration patch is, A skin regeneration patch sheet having a lower surface that is detachably coupled to the upper surface of the patch support sheet body and the upper surface of the patch knob; and A skin regeneration patch core comprising, which is coupled to the lower surface of the skin regeneration patch sheet and positioned in front of the patch knob. Skin regeneration patch assembly.

2. In Paragraph 1, The above patch support sheet is, An opening formed in the patch support sheet body, comprising a patch support knob opening in which the patch knob is located. Skin regeneration patch assembly.

3. In Paragraph 2, The above patch support sheet is, A patch support core opening formed in the patch support sheet body, wherein the skin regeneration patch core is located therein. Skin regeneration patch assembly.

4. In Paragraph 3, The patch support core opening and the patch support knob opening are, Communicating with each other Skin regeneration patch assembly.

5. In Paragraph 3, The above patch support core opening is, Located in front of the patch support knob opening, Skin regeneration patch assembly.

6. In Paragraph 1, The above patch support sheet is, It includes a patch support knob opening formed in the patch support sheet body, wherein the skin regeneration patch core is located therein. The patch knob is located in front of the patch support knob opening. Skin regeneration patch assembly.

7. In Paragraph 6, The rear end of the patch knob is formed along a part of the patch support knob opening, Skin regeneration patch assembly.

8. In Paragraph 6, The above patch support sheet body is, A patch attachment portion formed along the patch support knob opening and to which the skin regeneration patch sheet is attached, comprising Skin regeneration patch assembly.

9. In Paragraph 8, The above skin regeneration patch sheet is, A skin regeneration patch sheet support area coupled to the patch attachment portion above; A skin regeneration patch sheet core region coupled to the above skin regeneration patch core; and A skin regeneration patch sheet knob region detachably coupled to the patch knob above, Skin regeneration patch assembly.

10. In Paragraph 9, The skin regeneration patch sheet support area and the skin regeneration patch sheet knob area are, Deployed along the outer circumference of the core area of ​​the above-mentioned skin regeneration patch sheet, Skin regeneration patch assembly.

11. In Paragraph 1, A plurality of grooves are formed on the lower surface of the above-mentioned skin regeneration patch core, Skin regeneration patch assembly.

12. In Paragraph 11, Each of the above plurality of grooves is, Forming a shape extended in the front-rear direction, Skin regeneration patch assembly.

13. In Paragraph 12, The above plurality of grooves are, Arranged sequentially in left and right directions, Skin regeneration patch assembly.

14. In Paragraph 13, The above plurality of grooves are, Forming irregularities in the above left and right directions, Skin regeneration patch assembly.

15. A step of forming a patch support including a patch support sheet body and a patch support core opening formed in the patch support sheet body; A step of attaching a skin regeneration patch sheet to the patch support sheet body; and A step comprising combining a skin regeneration patch core with the skin regeneration patch sheet, Method for manufacturing a skin regeneration patch assembly.

16. In Paragraph 15, The above skin regeneration patch core is located in the opening of the above patch support core, Method for manufacturing a skin regeneration patch assembly.

17. In Paragraph 16, In the step of forming the patch support above, A patch knob is detachably coupled to the patch support sheet body. Method for manufacturing a skin regeneration patch assembly.

18. In Paragraph 17, The area of ​​the above skin regeneration patch sheet is, A skin regeneration patch core region coupled to the above skin regeneration patch core; A skin regeneration patch sheet support area coupled to the patch support sheet body; and A skin regeneration patch sheet knob area coupled to the above patch knob, Method for manufacturing a skin regeneration patch assembly.

Images