Intraoral device and arrangement

Abstract

The invention relates to an intraoral device (100) for placement in an oral cavity (110), comprising an active substance container (3) for receiving an active substance, an active substance dispensing unit (6) which is configured to dispense an active substance received in the active substance container (3), and a control unit (2) which is configured to control the active substance dispensing unit (6), wherein the intraoral device (100) has a radio interface (5) which is connected to the control unit (2) for data exchange, wherein the radio interface (5) is configured to receive control commands and to transmit them to the control unit (2). The invention further relates to an arrangement (300).

Description

[0001] INTRAORAL DEVICE AND ARRANGEMENT

[0002] TECHNICAL AREA

[0003] The present disclosure relates to an intraoral device for placement within the oral cavity. The disclosure further relates to an arrangement comprising an intraoral device and a user device. The intraoral device may, for example, be suitable for the controlled delivery of active substances within the oral cavity.

[0004] BACKGROUND

[0005] In the field of intraoral devices, it is common to use various devices for administering drugs or stimulating nerves and muscles within the oral cavity. Well-known devices typically include simple mechanical devices such as dental splints or mouthpieces, which are used for the passive release of drugs or for mechanical assistance in orthodontic treatment. These conventional devices are often limited in their functionality and do not offer the possibility of actively controlling or adjusting drug release or nerve stimulation.

[0006] This creates a need in the field of intraoral devices for devices that enable precise and individually adjustable drug release and / or targeted nerve and muscle stimulation.

[0007] Therefore, one of the technical problems underlying the present invention is to provide an intraoral device and arrangement that at least partially overcomes the disadvantages of known devices and systems.

[0008] SUMMARY

[0009] An object of the present invention is to provide an intraoral device according to claim 1 and an arrangement according to claim 31 that overcome one or more of the disadvantages of known devices. Advantageous embodiments are the subject of the respective dependent claims. A first aspect of the invention relates to an intraoral device for placement in the oral cavity, comprising an active ingredient reservoir for holding an active ingredient, an active ingredient delivery unit configured to deliver an active ingredient contained in the active ingredient reservoir, and a control unit configured to control the active ingredient delivery unit, wherein the intraoral device has a radio interface connected to the control unit for data exchange, the radio interface being configured to receive control commands and transmit them to the control unit.

[0010] This allows the release of the active ingredient to be controlled by control commands, which can be received, for example, via the radio interface.

[0011] A second aspect of the invention relates to an intraoral device for placement in the oral cavity, comprising a nerve stimulation unit and a control unit, wherein the nerve stimulation unit is configured to stimulate one or more nerves in the oral cavity when the intraoral device is placed in the oral cavity, wherein the control unit is configured to control the nerve stimulation unit, wherein the intraoral device has a radio interface that is connected to the control unit for data exchange, wherein the radio interface is configured to receive control commands and transmit them to the control unit.

[0012] This allows nerve stimulation to be controlled by control commands, which can be received, for example, via the radio interface.

[0013] In some versions, the nerve stimulation unit can be designed to stimulate nerves, nerve endings and / or muscles of the tongue.

[0014] A third aspect of the invention relates to an intraoral device comprising at least one sensor and a control unit, wherein the sensor is configured to detect one or more physical quantities of the oral cavity and / or one or more physical quantities within the oral cavity when the intraoral device is placed in the oral cavity, wherein the control unit is configured to receive a measured value from the sensor, wherein the intraoral device has a radio interface connected to the control unit for data exchange, and wherein the radio interface is configured to wirelessly transmit measured values ​​and / or values ​​calculated or determined by the control unit.

[0015] This allows measurements taken inside the mouth, and / or derived quantities or values, to be wirelessly transmitted to an external device.

[0016] It may be provided that the intraoral device according to the first aspect, the intraoral device according to the second aspect and / or the intraoral device according to the third aspect may have at least one, several or all features of at least one other aspect.

[0017] The intraoral device's wireless interface enables communication with the control unit, allowing for precise, real-time transmission of commands for drug delivery and / or nerve stimulation. This facilitates flexible and customizable control of drug delivery and / or nerve stimulation, tailored to the individual needs of the user. Wireless communication also enhances ease of use, eliminating the need for physical connections or cables, thus simplifying device handling.

[0018] The wireless interface enables communication with external devices, which, depending on the design, can facilitate remote control and monitoring of drug delivery and / or nerve stimulation. This can be particularly beneficial for patients requiring continuous or on-demand medication, as control commands for adjusting drug delivery can be received and transmitted to the control unit in real time.

[0019] The external device can include or be a user device. Alternatively or additionally, the external device can be or be a terminal device and / or a mobile device. The external device can be or be a smartphone, a tablet, a computer, and / or a server.

[0020] The radio interface can be configured to receive and / or transmit data in real time. For example, the radio interface can be configured to transmit data in real time to the control unit and / or to external devices. For example, the radio interface can be configured to receive data in real time from the control unit and / or from one or more external devices.

[0021] The radio interface can be configured to receive and / or transmit data via, for example, Bluetooth, WLAN, NFC, LTE, narrowband IoT, ANT+, ZigBee, and / or another suitable protocol. The radio interface can be configured for directional communication.

[0022] The wireless interface can, for example, enable or facilitate the integration of the intraoral device into existing healthcare systems and / or healthcare applications.

[0023] The wireless interface can enable remote monitoring and / or control, either as an alternative or additional feature. This can be particularly useful in clinical trials or for long-term patient monitoring, as it allows for detailed analysis of oral conditions, drug release, and / or nerve stimulation. Alternatively or additionally, it can also enable the diagnosis and detection of intraoral abnormalities, such as inflammation or infection. The wireless interface can facilitate diagnosis, potentially including remote diagnosis, and / or telemedicine.

[0024] The control unit can be configured to receive data from and / or transmit data to the radio interface. It can be designed to receive data and / or measurements from at least one sensor. It can also be designed to receive data from at least one camera.

[0025] The control unit can be configured to exchange data with the drug delivery unit. The control unit can be configured to exchange data with the nerve stimulation unit. The control unit can be configured to control the drug delivery unit and / or transmit control commands to the drug delivery unit. The control unit can be configured to control the nerve stimulation unit and / or transmit control commands to the nerve stimulation unit.

[0026] The control unit can create and / or generate control commands. The control unit can change, adapt, and / or modify control commands. The control unit can receive control commands from the radio interface and change, modify, and / or adapt the control commands received from the radio interface. The control unit can be configured to create and / or generate, and / or change, adapt, and / or modify control commands based on at least one measured value received from at least one sensor.

[0027] The control unit can be configured to combine, aggregate, and / or determine and / or calculate derived quantities from received data, control commands, and / or measured values.

[0028] The control unit can be or include a computer unit. The control unit can comprise one or more components such as a CPU, microcontroller, logic chip, transistor, FPGA, integrated circuit, or the like.

[0029] The intraoral device may include an energy storage device. The energy storage device may provide energy for the control unit, the radio interface, and / or, depending on the embodiment, the drug delivery unit, nerve stimulation unit, and / or sensors.

[0030] The active ingredient may be a medicinal substance or contain a medicinal substance. The active ingredient may be a therapeutic substance or contain a therapeutic substance. The active ingredient may be a drug or contain a drug. The active ingredient may be liquid and / or comprise a fluid. The active ingredient may be an ointment and / or have an ointment-like form. The active ingredient may be ionized and / or at least partially ionized. The active ingredient may be contained in a carrier fluid.

[0031] According to at least one embodiment, the intraoral device can be foil-shaped and / or include a foil. A foil-shaped intraoral device can flexibly adapt to the contours of the oral cavity, which can significantly increase wearing comfort and / or improve user acceptance. In some embodiments, this flexible adaptation can facilitate or evenly distribute the active ingredient within the oral cavity, leading to more efficient and targeted drug delivery. Furthermore, the foil-shaped structure can allow for discreet placement of the intraoral device in the mouth, which is particularly advantageous in social settings, as the device may be barely visible and the user's speech may be unaffected or only minimally impaired.Using a film can also reduce manufacturing costs, as film materials are generally less expensive and easier to process than rigid materials. In some designs, the film can also be impregnated or coated with various active ingredients, increasing the versatility of the intraoral device and allowing it to be adapted to different therapeutic needs. Integrating the wireless interface and control unit into a film-like structure ensures that the device's technological components remain compact and discreet despite their complexity. The film design can also improve hygiene, as it is easy to clean or can be designed as a disposable product, minimizing the risk of infection or contamination.

[0032] According to at least one embodiment, the intraoral device can be designed to be positioned on the tongue within the oral cavity. This specific arrangement can enable precise and controlled delivery of the active ingredient directly onto or over the tongue, which can promote rapid absorption of the active ingredient into the bloodstream. Placing the device on the tongue allows for more efficient and faster absorption of the active ingredient, as the tongue is, for example, well-vascularized and / or offers a large surface area for absorption. Furthermore, positioning on the tongue can improve usability, as the device may be less intrusive and may have less impact on normal oral function. Positioning the device on the tongue can also enhance the discretion of its use, as it may be less visible and thus allow for inconspicuous use in social situations.Furthermore, placing the device on the tongue can increase dosing accuracy, as it allows the device to be held in a stable position and the active ingredient to be released precisely. In some embodiments, a tongue-based arrangement can also increase application safety, as the device sits firmly on the tongue, minimizing the risk of swallowing or misplacement.

[0033] In at least one embodiment, the intraoral device can be or include a dental splint. The dental splint can have or form a support structure that facilitates the integration of various components such as the drug delivery unit, the control unit, and / or the wireless interface, as well as, depending on the embodiment, the drug delivery unit, the nerve stimulation unit, and / or the sensor. Using a dental splint can optimize and / or facilitate the positioning of the intraoral device within the oral cavity, which can, for example, ensure precise and controlled drug delivery. The dental splint can enable stable and secure placement in the mouth, which, depending on the embodiment, can improve the functionality of the drug delivery unit, the nerve stimulation unit, the sensor, and / or the control unit.One advantage of integrating the medication into a dental splint is increased user-friendliness, as the device can be worn discreetly and comfortably without interfering with normal mouth closure or speech. Furthermore, the splint can ensure an even distribution of the medication within the oral cavity, potentially enhancing treatment effectiveness. The splint can be made of biocompatible materials suitable for long-term oral use, increasing user safety and comfort. Integrating the various components into the splint can reduce the overall size of the intraoral device, improving patient acceptance and compliance. In some designs, the splint can be individually adapted to the user's dental structure, ensuring an optimal fit and stability.The dental splint can also be designed to be easy to clean and maintain, which can promote the hygiene and longevity of the intraoral device.

[0034] According to at least one embodiment, the intraoral device includes at least one sensor connected to the control unit and / or the radio interface for data exchange. For example, the sensor can acquire various types of data relevant to controlling and monitoring drug delivery and / or nerve stimulation. For instance, the sensor can measure the user's physiological parameters such as salivary flow, temperature, or pH. This data can then be transmitted to the control unit, which can adjust the drug delivery and / or nerve stimulation accordingly. Integrating the sensor into the intraoral device enables more precise and individualized drug dosing and / or nerve stimulation control, potentially leading to improved therapeutic efficacy.The sensor can also be used to monitor the condition of the intraoral device itself, such as the fill level of the drug container or the battery status, and to transmit this information to an external device via the wireless interface. This can enable proactive maintenance and prevent or at least reduce unexpected failures of the intraoral device.

[0035] Alternatively or additionally, the sensor can be configured to record diagnostic or therapeutic values ​​and / or physical quantities of the oral cavity and / or within the oral cavity. The recorded values ​​can then be transmitted, for example, via a wireless interface to an external device. This enables remote diagnostics.

[0036] The sensor can, for example, continuously and / or at regular intervals acquire measured values, and / or continuously and / or at regular intervals transmit data and / or measured values ​​to the control unit.

[0037] Connecting the sensor to the control unit and / or the wireless interface ensures that the collected data can be processed and used in real time, further increasing the efficiency and reliability of drug delivery and / or nerve stimulation. An advantage of this configuration is the ability for healthcare professionals to remotely monitor and control the intraoral device, which can be particularly important in cases of chronic disease or during postoperative care. The wireless interface enables the secure and efficient transmission of collected data to an external device, such as a smartphone, tablet, computer, or server, thus ensuring seamless integration into existing healthcare systems and applications.Another advantage is the potential use of data analysis algorithms based on collected sensor data to generate personalized treatment recommendations. This can further improve the adaptation of therapy to the individual needs and current health status of the user.

[0038] In at least one embodiment, the sensor may include a pressure sensor and / or be a pressure sensor itself. The pressure sensor may be integrated as a separate sensor and / or function as part of a multifunctional sensor system. In some embodiments, the pressure sensor may be configured to detect tongue contact when the intraoral device is inserted into the oral cavity. Alternatively or additionally, the pressure sensor may be configured to detect oral cavity closure when the intraoral device is inserted into the oral cavity. The pressure sensor can detect physical interactions within the oral cavity, which may enable more precise control of drug delivery and / or nerve stimulation.By detecting tongue contact, the pressure sensor can recognize when the tongue touches the intraoral device, which can trigger the delivery of the drug and / or nerve stimulation. This enables, for example, on-demand and / or user-initiated drug delivery and / or nerve stimulation. The pressure sensor may also be configured to register when the mouth is closed. This function can be used to ensure that drug delivery only occurs when the mouth is closed, increasing the likelihood of correct drug absorption and avoid waste. Similarly, nerve stimulation may only occur when the mouth is closed. In some embodiments, information and / or measurements acquired by the pressure sensor may be transmitted to the control unit.

[0039] According to at least one embodiment, the sensor can include and / or be a contact sensor. The contact sensor can, for example, be integrated as a separate sensor and / or function as part of a multifunctional sensor system. The contact sensor can be configured to detect a closed contact of the oral cavity when the intraoral device is inserted into the oral cavity. The contact sensor can, for example, respond to physical contact. The contact sensor can monitor the state of the oral cavity, in particular whether the device is correctly positioned and the mouth is closed. The contact sensor can be contacted when the mouth is closed or becomes closed. For example, when the mouth is closed, the contact sensor can be contacted by teeth in the oral cavity.It can be designed so that the control unit, drug delivery unit, and / or nerve stimulation unit can only be activated when the contact sensor detects a closed position of the oral cavity, particularly when the device is correctly positioned and the mouth is closed. This can minimize the risk of inadvertent drug delivery. For example, it can ensure that the drug is released only under optimal conditions. Furthermore, the contact sensor can improve the usability of the device by providing feedback to the user or the control unit that the device has been inserted correctly. This can be especially useful in medical applications where precise dosage and placement are critical.

[0040] In at least one embodiment, the sensor may include a temperature sensor and / or be a temperature sensor itself. The temperature sensor may be integrated as a separate sensor and / or function as part of a multifunctional sensor system. The temperature sensor may be configured to detect the temperature of the oral cavity when the intraoral device is inserted. The temperature sensor can enable more precise monitoring of the oral environment, which can be crucial for optimal drug release and / or nerve stimulation. The temperature of the oral cavity can influence the solubility and release rate of the drug. By continuously monitoring the temperature, the control unit of the intraoral device can adjust drug delivery in real time to ensure consistent and effective dosing.Furthermore, the temperature sensor can contribute to increased comfort and safety of the intraoral device. For example, the device can be configured to trigger alarms and / or stop drug delivery and / or nerve stimulation when certain temperature limits are reached to prevent overheating or undercooling. Additionally, the temperature sensor can enable more comprehensive data collection, which can be used for treatment analysis and optimization. The collected temperature data can be transmitted wirelessly to external devices or systems for remote monitoring and / or control. This can be particularly useful in clinical trials or long-term patient monitoring, as it allows for detailed analysis of oral conditions and drug release.Furthermore, temperature measurement can also contribute to the diagnosis and detection of abnormalities in the oral cavity, such as inflammation or infections, which can be signaled by temperature changes.

[0041] In at least one embodiment, the sensor can include a pH sensor and / or be a pH sensor itself. The pH sensor can be integrated as a separate sensor and / or function as part of a multifunctional sensor system. The pH sensor can be configured to measure the pH value in the oral cavity when the intraoral device is inserted. This enables pH monitoring, which can be beneficial for various medical and dental applications. The oral pH value can provide important information about the patient's health, such as the risk of caries or other oral diseases. By integrating a pH sensor, the intraoral device can continuously or at regular intervals measure the pH value and transmit this data to the control unit.Based on the received data, the control unit can send appropriate control commands to the drug delivery unit to regulate, for example, the release of an active ingredient. For instance, the active ingredient may be particularly effective at a specific pH level, and it may be designed so that the drug is only released when the pH is within a certain range. Similarly, a physical property of the drug may depend on the pH level in the oral cavity, and it may be designed so that the drug is only released when the pH is within a specific range. Furthermore, continuous pH monitoring can help detect early signs of problems and allow for timely countermeasures.

[0042] In at least one embodiment, the sensor may include a motion sensor and / or be a motion sensor itself. The motion sensor may be integrated as a separate sensor and / or function as part of a multifunctional sensor system. The motion sensor may be configured to detect tongue movements within the oral cavity when the intraoral device is inserted. The motion sensor can enable monitoring and / or detection of tongue movements, which can offer a variety of advantages. For one, detecting tongue movements can help optimize the dosage and release of the drug by the drug delivery unit. For example, it may be possible to ensure that the drug is released precisely when the tongue is in a specific position, which can increase the efficiency of drug absorption.For example, it may be planned to perform nerve stimulation when the tongue is in a certain position.

[0043] The motion sensor enables interaction between the intraoral device and the user's tongue. For example, a patient can control drug delivery, such as initiating or stopping it, by making a predefined tongue movement. Similarly, a patient can control nerve stimulation, such as initiating or stopping it, by making a predefined tongue movement.

[0044] Another advantage of using a motion sensor is the ability to transmit the data it captures in real time to the control unit and, if necessary, to external devices via the wireless interface. This allows for continuous monitoring and adjustment of treatment, leading to improved patient safety and satisfaction. Furthermore, the motion sensor can help extend the lifespan and efficiency of the intraoral device by preventing or at least reducing unnecessary drug delivery and / or optimizing drug consumption.

[0045] In at least one embodiment, the sensor may include a flow sensor and / or be a flow sensor itself. The flow sensor may be configured to detect fluid and / or airflow within the oral cavity when the intraoral device is inserted. The flow sensor may, for example, be integrated as a separate sensor and / or function as part of a multifunctional sensor system. Detecting fluid and / or airflow within the oral cavity can offer several advantages. One advantage is the precise monitoring of the intraoral environment, which can enable more accurate control of drug delivery and / or nerve stimulation. In some embodiments, the flow sensor may, for example, detect whether the user is currently drinking liquids, providing relevant information for adjusting drug delivery.In some embodiments, the flow sensor can detect, for example, a user's respiratory rate and / or volumetric or mass flow rate of exhaled air. Furthermore, the flow sensor can contribute to increasing the safety of the intraoral device by detecting potentially hazardous situations such as aspiration or airway obstruction. The data acquired by the flow sensor can be transmitted to the control unit, which can then control the drug delivery unit and / or nerve stimulation accordingly. It may also be possible to transmit the data acquired by the flow sensor to an external device via the wireless interface.

[0046] According to at least one embodiment, the intraoral device may include a camera. The camera may be configured to capture mouth movements when the intraoral device is positioned inside the mouth. Alternatively or additionally, the camera may be configured to capture lip and / or tongue movements when the intraoral device is positioned inside the mouth. Alternatively or additionally, the camera may be configured to capture tongue movements when the intraoral device is positioned inside the mouth.

[0047] The camera can monitor and analyze movements within the oral cavity, enabling improved control and adjustment of drug delivery and / or nerve stimulation. Capturing mouth, lip, and / or tongue movements can help optimize drug delivery in real time, ensuring, for example, that the drug is released at the optimal times and locations in the mouth. This can be particularly beneficial for treating conditions requiring targeted and precisely timed drug delivery. Furthermore, the camera can be used to monitor the correct positioning of the intraoral device, further enhancing treatment effectiveness.Integrating a camera into the intraoral device can provide visual data that can be processed by the control unit to precisely control drug delivery and / or nerve stimulation. This visual feedback can also enhance the device's usability by allowing the user or healthcare professional to monitor its operation and make adjustments as needed. The data captured by the camera can be used to analyze and document treatment, providing valuable insights into treatment progress and therapy effectiveness. The camera can also be used to detect anomalies or changes in the oral cavity that might indicate potential complications or the need for treatment adjustments.By providing this additional data source, the intraoral device can become an even more powerful and versatile tool in medical treatment. The device's wireless interface can transmit the data captured by the camera to external devices, enabling seamless integration with existing medical monitoring systems and easy data sharing with medical professionals. This can lead to an improvement in the overall quality of patient care and support personalized and precise medical treatment.

[0048] According to at least one embodiment, the intraoral device may include a nerve stimulation unit. The nerve stimulation unit may be configured to stimulate a nerve. Alternatively or additionally, the nerve stimulation unit may be configured to stimulate a nerve ending. Alternatively or additionally, the nerve stimulation unit may be configured to stimulate a muscle. The nerve may be a nerve of the oral cavity and / or a nerve within the oral cavity, for example, a nerve of the tongue. The nerve ending may be a nerve ending of the oral cavity and / or a nerve ending within the oral cavity, for example, a nerve ending of the tongue. The muscle may be a muscle of the oral cavity and / or a muscle within the oral cavity, for example, a muscle of the tongue.

[0049] The nerve stimulation unit may have an electrode that can stimulate a nerve, nerve ending and / or muscle by means of an electrical current.

[0050] This nerve stimulation unit can be used for therapeutic and / or diagnostic purposes. It can generate electrical impulses that can be targeted to specific nerves or muscles to influence their activity. This can be used, for example, for pain relief, treatment of muscle tension, or to support rehabilitation after injuries. Integrating the nerve stimulation unit into the intraoral device allows for precise and controlled stimulation. The control unit can regulate the intensity, duration, and / or frequency of the electrical impulses. Furthermore, the wireless interface allows the nerve stimulation unit to be remotely controlled, enabling flexible and user-friendly operation.One advantage of the nerve stimulation unit is the ability to individually tailor the stimulation to the user's needs, which can increase the effectiveness of the treatment. Another advantage is the minimization of side effects, as the stimulation can be targeted and precisely dosed. Combining drug delivery with nerve stimulation can, for example, integrate pharmacological and physical therapy. This can be particularly beneficial in complex conditions where a multimodal therapeutic approach may be necessary. The nerve stimulation unit can also be used to diagnose nerve and muscle function by measuring and / or analyzing the response to electrical impulses. This can provide valuable information about the condition and functionality of the nerves and muscles, which can be used for planning and monitoring treatment measures.The nerve stimulation unit can expand the therapeutic and diagnostic capabilities of the intraoral device and, for example, contribute to improved patient care. According to at least one embodiment, the nerve stimulation unit can be configured to stimulate one or more nerves and / or nerve endings of the tongue within the oral cavity when the intraoral device is inserted. The nerve stimulation unit can generate electrical impulses or other forms of stimulation that can specifically target the nerves and / or nerve endings of the tongue. The nerve stimulation unit can be configured to be activated and / or controlled by commands from the control unit.The nerve stimulation unit can be configured to be activated or activated depending on the control commands received via the radio interface and the control unit.

[0051] This allows for precise and controlled stimulation of the lingual nerves, which can lead to various therapeutic or diagnostic benefits. One advantage of the nerve stimulation unit is the ability to selectively stimulate specific nerves to, for example, increase saliva production, improve swallowing reflexes, or influence sensory and motor functions of the tongue. This can be particularly beneficial for patients with neurological disorders or swallowing difficulties. Alternatively or additionally, nerve stimulation can be used to generate and / or simulate taste.

[0052] Another advantage is the non-invasive nature of the stimulation, as the intraoral device can be easily inserted into the oral cavity without the need for surgery. By using a wireless interface to transmit control commands to the control unit, the nerve stimulation unit can be flexibly and individually adjusted, enabling personalized therapy. This can increase treatment effectiveness and improve patients' quality of life. The nerve stimulation unit can also work in conjunction with the drug delivery unit to achieve synergistic effects, such as simultaneously delivering medication and stimulating nerves to enhance drug absorption and efficacy.

[0053] In at least one design, the nerve stimulation unit can be configured to generate and / or simulate a taste through targeted nerve stimulation. This nerve stimulation unit can interact with the nerves in the oral cavity to generate sensory signals that the brain interprets as specific tastes. The unit's functionality can be based on the precise application of electrical impulses that target taste buds. These impulses can be modulated to elicit various tastes such as sweet, salty, sour, bitter, or umami. One advantage is the ability to create taste sensations without the need to introduce any physical substances into the mouth, which can be particularly beneficial for individuals with dietary restrictions or allergies.Furthermore, this technology can be used in therapeutic applications to stimulate or regulate appetite, which could be beneficial for patients with eating disorders or loss of appetite. Another advantage is its potential application in the food industry, where it can be used to develop new taste experiences or improve existing products. The ability to simulate flavors precisely and reproducibly can open up new possibilities for personalized taste experiences.

[0054] The nerve stimulation unit can be connected to the control unit of the intraoral device. The control unit can regulate and / or control the intensity, duration, and / or frequency of the electrical impulses. The control unit can receive commands via the radio interface, enabling wireless communication with external devices. This allows for flexible and user-friendly control of taste stimulation by the user or by automated systems.

[0055] In at least one version, the nerve stimulation unit can be configured to alleviate pain through nerve stimulation. The nerve stimulation unit can generate various types of electrical impulses that can target specific nerves in the oral cavity to modulate or block pain signals. This targeted nerve stimulation can achieve or result in pain relief, which can be beneficial, for example, in the treatment of acute or chronic pain in the oral cavity. The ability to control the nerve stimulation via a wireless interface can offer increased user-friendliness and adaptability, as the intensity and / or frequency of the stimulation can be individually adjusted. This can be particularly useful in situations where the user experiences varying degrees of pain and flexible adjustment of the stimulation is required.A combination of drug delivery and nerve stimulation in a single device can offer a comprehensive pain management solution by integrating both pharmacological and non-pharmacological methods. This can increase the effectiveness of pain treatment and reduce the need for systemic analgesics, which in turn can lower the risk of side effects.

[0056] The nerve stimulation unit can interact with the device's control unit. The control unit can be operated, for example, via the wireless interface. This interface allows control commands to be received and transmitted wirelessly to the control unit, ensuring precise and flexible control of the nerve stimulation unit.

[0057] Another advantage of wireless control is that the intraoral device can be operated without a physical connection to external control units, which can increase the user's comfort and mobility.

[0058] In at least one version, the nerve stimulation unit can be configured to be controlled by the control unit. This nerve stimulation unit can be configured to selectively stimulate nerves within the oral cavity to achieve therapeutic or diagnostic effects. Control of the nerve stimulation unit by the control unit enables precise and controlled application of the nerve stimulation. This can be supported, for example, by the wireless interface, which can receive and / or transmit control commands to the control unit. The ability to control the nerve stimulation unit via the control unit allows for individual adjustment of stimulation parameters such as intensity, frequency, and / or duration, which can optimize the effectiveness of the treatment.Furthermore, the wireless interface can be used to monitor and adjust the stimulation parameters in real time, enabling flexible and dynamic adaptation to the user's needs. Another advantage of the described embodiment is its potential application in various therapeutic areas, such as pain therapy, the treatment of neurological disorders, or the promotion of wound healing in the oral cavity. Control of the nerve stimulation unit by the control unit also ensures high precision and safety during application, as the stimulation parameters can be precisely monitored and adjusted.

[0059] In some embodiments, the control unit can create, adapt, and / or modify one or more control commands. The control command can be created, adapted, and / or modified based on values ​​acquired by at least one sensor. The control command can be received from the radio interface, and / or control commands received from the radio interface can be adapted and / or modified by the control unit. It may be provided that a control command received from the radio interface can instruct the control unit, for example, to create, change, and / or modify a control command for the nerve stimulation unit. The control unit may be configured to adapt and / or modify a control command received from the radio interface based on one or more values ​​acquired by at least one sensor.

[0060] The control command can be transmitted from the control unit to the nerve stimulation unit in order to control the nerve stimulation unit.

[0061] According to at least one embodiment, the drug delivery unit can include a membrane. The membrane can be fluidically connected to the drug container. Alternatively or additionally, the membrane can be located within the drug container. The membrane can be designed to respond to specific control commands, which are received, for example, via the radio interface and forwarded to the control unit, and / or which are generated, changed, and / or modified by the control unit. This can enable flexible and demand-based delivery of the drug, particularly when different dosages or schedules may be required. Another advantage of the membrane is its ability to act as a barrier, protecting the drug from external influences. This can, for example, improve the stability and shelf life of the drug.

[0062] According to at least one embodiment, the drug delivery unit can include a membrane adjustment unit. This membrane adjustment unit can be configured to adjust the membrane's permeability to the drug contained in the drug reservoir. The membrane adjustment unit can enable precise control of drug release by adjusting the membrane's permeability. This allows, for example, individualized and / or needs-based dosing of the drug. This can be advantageous in therapeutic applications where accurate dosing is crucial for the efficacy and safety of the treatment. By adjusting the membrane permeability, the drug release rate can be dynamically adapted to the patient's specific needs, potentially leading to improved therapeutic efficacy and a reduction in side effects.The drug delivery can also be adapted in real time to the patient's physiological conditions. A further advantage of this embodiment is the ability to use different drugs with varying physicochemical properties in the same intraoral device and / or to include them in the drug container, since the membrane adjustment unit can adapt the membrane's permeability accordingly. This can increase the flexibility and versatility of the intraoral device and / or expand the range of possible applications.

[0063] In at least one embodiment, the membrane adjustment unit can be configured to set the membrane temperature, whereby the membrane's permeability can be temperature-dependent. The membrane adjustment unit allows for precise control of the membrane temperature, which can directly affect the membrane's permeability. This allows the membrane's permeability to the active ingredient to be varied. This can be particularly advantageous for controlling the release rate of the active ingredient and adapting it to the individual needs of the user. For example, a higher temperature can increase the membrane's permeability and thus enable a faster release of the active ingredient, while a lower temperature can decrease the permeability and slow the release, depending on the membrane material.Alternatively, for some membrane materials, a higher temperature can, for example, decrease the membrane's permeability and thus slow down the release of the drug, while a lower temperature can increase permeability and accelerate release. This allows for flexible and dynamic adjustment of drug delivery, which can be particularly advantageous in situations requiring precise dosing and timed control of drug release. The ability to influence membrane permeability through temperature control can also help maintain the stability and efficacy of the drug by ensuring release under optimal conditions.The control unit can be configured to continuously adjust temperature conditions based on received control commands, values ​​received from at least one sensor, and / or the user's current needs. The wireless interface can enable communication between external devices and the control unit, allowing for remote control and monitoring of drug delivery.

[0064] According to at least one embodiment, the membrane adjustment unit can be configured to generate an electromagnetic field that acts on a membrane. In some embodiments, the permeability of the membrane can be adjusted by means of this electromagnetic field. The membrane can then allow the controlled release of the active ingredient from the drug container into the oral cavity. The electromagnetic field allows for dynamic and precise control of the membrane's permeability. This offers the advantage that the release rate of the active ingredient can be adapted to the individual needs of the user, which can lead to an optimized therapeutic effect. Controlling the permeability via an electromagnetic field provides a contactless and rapid adjustment method, thereby minimizing, for example, mechanical wear and potential contamination risks.Furthermore, this allows for finer control of drug delivery compared to conventional mechanical control mechanisms. Another advantage is the ability to monitor and adjust membrane permeability in real time, enabling precise dosing and timely drug release. This is particularly beneficial in applications where precise control of drug delivery is crucial for treatment efficacy.

[0065] According to at least one embodiment, a drug delivery unit can include a sealing film. The sealing film can be fluidically connected to the drug container. Alternatively or additionally, the sealing film can be fluidically connected to the membrane. Alternatively or additionally, the sealing film can close the drug container. In some embodiments, the sealing film can be designed to dissolve at least partially when the intraoral device is inserted into the oral cavity. For example, the sealing film can be water-soluble and / or be at least partially dissolved by saliva. The sealing film can serve as a protective barrier that can keep the drug isolated in the container until actual use. This can, for example, improve the stability and shelf life of the drug.The fluidic connection between the sealing film and the drug container and / or membrane ensures that the drug is released in a controlled and efficient manner once the film dissolves. This allows for precise dosing and release of the drug, which can be particularly important for the efficacy and safety of administration. The ability of the sealing film to dissolve within the oral cavity offers the advantage of simple and convenient application, as manual removal of the film is not required. This can improve the usability and acceptance of the intraoral device, especially for patients who have difficulty handling complex medical devices. Furthermore, the dissolvable sealing film can minimize the risk of drug contamination, as it can form a sterile barrier until the time of administration.Integrating the sealing foil into the drug delivery unit can ensure that the drug is only released when the device is positioned inside the mouth, which can support the targeted and timely delivery of the drug.

[0066] In at least one embodiment, the drug delivery unit can have at least one electrode. The electrode can be designed to contact the skin and / or mucous membrane when the intraoral device is inserted into the oral cavity. The electrode can perform various functions, such as releasing the drug through electrical stimulation or improving drug absorption through the mucous membrane by means of iontophoresis and / or electroporation. The electrode can enable controlled and metered delivery of the drug, which can lead to improved efficacy and efficiency of the treatment. Furthermore, the electrode can help prolong the residence time of the drug at the application site by enabling continuous or pulsed release.This can be advantageous in the treatment of diseases or conditions requiring prolonged drug exposure. The intraoral device's wireless interface allows control commands to be received wirelessly and transmitted to the control unit, ensuring flexible and user-friendly control of drug delivery. The ability to regulate drug delivery via an external device can offer additional benefits in terms of tailoring treatment to the individual needs of the patient.

[0067] It may be provided that the drug delivery unit can be configured to introduce and / or transport the drug into the skin and / or mucous membrane by means of iontophoresis.

[0068] The drug delivery unit can have one or more electrodes. In iontophoresis, electric currents are used to introduce charged drugs through the skin and / or mucous membranes into underlying tissue. The charged drugs can be ionized, and / or an ionized drug can be a charged drug. Ionized drugs can move under the influence of an electric field.

[0069] Two electrodes can make contact with the skin and / or mucous membranes. The active ingredient can be contained in a gel or solution within the drug container. When an electric current is activated, the ions of the active ingredient can move towards the electrode with the opposite charge, and in doing so, can be transported, for example, through the skin and / or mucous membranes. This movement of the ions through the skin barrier can promote the absorption of the active ingredient into the tissue. The strength and duration of the current can be adjusted and / or controlled to achieve the desired effect. Iontophoresis can enable targeted and painless drug delivery.

[0070] According to at least one embodiment of the invention, the electrode can be configured to conduct an electric current to generate an electric field and deliver an ionized active ingredient from the active ingredient container into the skin and / or mucous membrane. The electrode conducting the electric current can generate an electric field that efficiently transports the ionized active ingredient through the skin or mucous membrane. This can offer the advantage of targeted and controlled drug delivery, which can be further optimized by controlling electrical parameters such as current intensity and the duration of the electric field. Another advantage of this embodiment is the minimization of drug losses and the maximization of drug efficacy, since the ionized active ingredient can be delivered directly to the desired site.Integrating the electrode into the intraoral device expands the functionality and increases the versatility of the device, as it can be suitable for transdermal or transmucosal application.

[0071] In at least one embodiment, the drug delivery unit can have a cathode and an anode. This specific configuration of the drug delivery unit enables precise and controlled delivery of the drug through electrochemical mechanisms. The cathode and anode work together to conduct an electric current through the medium containing the drug. The drug can be ionized. The ionized drug can be suspended in a carrier fluid. The current can control the release of the drug from the container into the user's oral cavity. This allows for precise dosing of the drug, as the amount of drug delivered can be precisely regulated by controlling the electric current. Furthermore, for example...The delivery of the active ingredient can be precisely timed, which can be particularly useful when the drug needs to be released at specific times or intervals. Furthermore, the stability of the drug can be improved by creating a controlled delivery environment. In addition, the delivery of the drug can be monitored and adjusted by the control unit of the intraoral device, enabling flexible and adaptable treatment. The wireless interface allows control commands to be received wirelessly and transmitted to the control unit, which in turn can control the drug delivery unit. This enables remote monitoring and / or control of drug delivery, which can be particularly advantageous in telemedicine applications or when treating patients who require continuous monitoring and adjustment of their medication.

[0072] It may be provided that the drug delivery unit can be configured to introduce and / or transport the drug into the skin and / or mucous membrane by electroporation.

[0073] The drug delivery unit may include an electrode. An electrode may contact the skin and / or mucous membrane, for example, at the site where electroporation is to be performed. The drug may be present in a suitable form, often as a solution or gel, within the drug container.

[0074] An electric field can be generated by the drug delivery unit and / or the electrode. For example, short, high-frequency electrical pulses can be passed through the electrode. These pulses can temporarily destabilize the cell membranes of the surrounding cells. The voltage and duration of the pulses can be controlled, for example, to ensure that the cells open without being damaged. During this period, microscopic pores can form in the cell membranes, allowing drugs to diffuse through or into the cell membrane. After the electrical pulses are switched off, the pores can close again, and the cells can resume their normal function. Direct delivery into the cells eliminates the need for the drug to first be absorbed into the bloodstream.This can often lead to a faster and more effective response to treatment.

[0075] Depending on the design, the drug delivery unit can be configured to generate an electric field that increases the permeability of the cell membrane, skin, and / or mucous membrane in the oral cavity. For example, the electric field can be generated by an electrode. This increased permeability can allow an active ingredient contained in the drug reservoir to penetrate the cell membrane, mucous membrane, and / or skin more efficiently. The drug delivery unit can also be configured to induce electroporation and / or introduce the active ingredient into the skin and / or mucous membrane via electroporation. This can, for example, lead to faster and greater absorption of the active ingredient into the target tissue, resulting in an improved therapeutic effect.The ability to modulate the permeability of cell membranes and other tissues in the oral cavity can provide precise control over drug delivery and / or enable targeted and dosed release of the active ingredient. This can be advantageous, for example, in the treatment of conditions requiring rapid and direct drug absorption. Some versions may incorporate control commands received by the control unit and / or via the wireless interface, allowing for flexible and adaptable application tailored to the individual needs of the user. Wireless communication allows parameters such as the intensity and duration of the electric field to be adjusted in real time, enabling personalized and optimized therapy.This can minimize or reduce side effects in some formulations by ensuring precise dosage and targeted delivery of the active ingredient.

[0076] In at least one embodiment, the drug delivery unit can be additionally configured to generate an electrical pulse when the electric field is created. Generating an electrical pulse can modulate and / or enhance the release of the drug. The electrical pulse can offer various advantages, such as improved penetration of the drug into tissue or targeted stimulation of specific nerves or cells in the oral cavity. This can be particularly useful for treating conditions that require precise and controlled drug delivery, such as local pain management or hormone delivery. The generation of an electrical pulse by the drug delivery unit can synchronize and optimize drug release, potentially leading to more efficient drug utilization.

[0077] According to at least one embodiment of the invention, the drug delivery unit can be configured to open a pore in the cell membrane, mucous membrane, and / or skin, allowing the drug to penetrate through or into the pore. The drug delivery unit can be configured to perform electroporation. This specific function of the drug delivery unit can ensure that the drug is delivered efficiently and precisely to the desired locations within the oral cavity. The ability to open pores can enable improved absorption of the drug, leading to a faster and more effective therapeutic effect. The control unit can monitor and / or regulate the drug delivery. The control unit can control the drug delivery unit to ensure that the drug is delivered in the correct dosage and at the correct time. The ability of the drug delivery unit to open pores can, for example,This can be particularly advantageous for the delivery of active ingredients that are normally difficult to penetrate through cell membranes, mucous membranes, or skin. This can increase the effectiveness of medications intended for the treatment of oral diseases or systemic conditions requiring oral administration.

[0078] It may be provided that the drug delivery unit can be configured to introduce and / or transport the drug into the skin and / or mucous membrane by or with sonophoresis.

[0079] A sound generator can be used to produce a sound wave, particularly ultrasound. The drug delivery unit can include a suitable sound generator. The active ingredient can be present in the drug container in a suitable form, e.g., as a solution or gel.

[0080] The sound waves can, for example, penetrate tissue and generate micro-vibrations that can temporarily loosen cell membranes. This can create small pores in the cell membrane, allowing the active ingredient to penetrate the cells more effectively. The intensity, frequency, and duration of the sound application can be precisely controlled to achieve the desired effects while simultaneously preventing cell damage. The active ingredient can then penetrate the opened pores, allowing it to enter the bloodstream or directly into the target cells more quickly and effectively, thus enhancing the therapeutic effect.

[0081] Depending on the design, the drug delivery unit can be configured to generate sound waves. These sound waves can be, for example, ultrasound, or the drug delivery unit can be configured to generate ultrasound or ultrasonic waves. The sound waves can lead to the formation of cavitation, particularly cavitation bubbles, within the drug. This mechanism can increase the permeability of cell membranes, skin, and / or mucous membranes in the oral cavity. The generation of sound waves, especially ultrasound, can enable precise and controlled delivery of the drug, as the cavitation bubbles can cause microscopic movement and mixing of the drug. This can improve the absorption of the drug by tissues in the oral cavity.One advantage of this method can be the increased efficiency of drug delivery, as the sound waves can make cell membranes more permeable, leading to improved bioavailability of the drug. Another advantage is the ability to precisely control the dosage and delivery of the drug, minimizing the risk of overdosing or underdosing. The use of sound waves, such as ultrasound, to generate cavitation and / or cavitation bubbles can ensure that the drug is distributed evenly and reaches deeper layers of the mucous membrane. This can be beneficial, for example, in the treatment of oral diseases. The drug delivery unit can be configured to perform sonophoresis. It may be designed to deliver the drug into the skin and / or mucous membrane via sonophoresis.

[0082] In at least one embodiment, the sound waves can be applied to the skin and / or mucous membrane of the oral cavity, causing it to vibrate. This specific design can enable improved drug delivery through the vibration of the skin and / or mucous membrane, which can increase tissue permeability. The vibrations can expand the intercellular spaces and promote blood circulation, leading to more efficient absorption of the active ingredient.

[0083] The sound waves can be generated, for example, by an integrated transducer, which may be built into the intraoral device. The drug delivery unit may include one or more of these transducers. The transducer can, for example, convert electrical signals from the control unit into mechanical vibrations that can then be transmitted to the skin and / or mucous membranes. The use of sound waves can, for example, reduce the need for higher drug doses, which can increase the safety and tolerability of the treatment.

[0084] Another aspect of the disclosure concerns an arrangement comprising an intraoral device according to one aspect of the disclosure and a user device, wherein the user device has a data transmission unit configured for wireless data exchange with the radio interface of the intraoral device.

[0085] The user device enables wireless communication with the intraoral device, facilitated by the device's data transmission unit. This wireless communication allows for flexible and user-friendly control of the intraoral device, as the user does not need to interact directly with the device but can do so via the user device. Furthermore, wireless communication can ensure precise and timely drug delivery, as control commands can be transmitted in real time. Additionally, the wireless connection can allow the intraoral device to be paired with other systems or devices, enabling enhanced functionality and adaptability.For example, the user device could be a smartphone or other portable device that may have an app or dedicated software to facilitate control of the intraoral device. For instance, the device could also enable the collection and analysis of data on drug delivery and the user's use of the intraoral device, leading to improved monitoring and treatment adjustment. One advantage of wireless communication could be the ability to remotely monitor and control the intraoral device, which can be particularly useful if the user requires assistance from healthcare professionals. The wireless data transmission unit of the user device could utilize Bluetooth, Wi-Fi, LTE, GSM, narrowband IoT, ANT+, ZugBee, or other suitable wireless communication protocols.

[0086] In some implementations, a control command can be created or generated by the user device and transmitted to the radio interface of the intraoral device via the data transmission unit.

[0087] According to at least one embodiment, the user device can include or be a head device. The head device can be designed to be positioned and / or attached to a head. For example, the head device can be a headband, goggles, or a helmet. The head device can be equipped with additional sensors or communication modules. These sensors could, for example, capture biometric data such as heart rate, respiratory rate, or temperature and transmit this information to the control unit via the data transmission unit. Wireless communication allows control commands and sensor data to be transmitted in real time, which can significantly improve the flexibility and adaptability of the intraoral device.Another advantage of the head device is its ability to be individually adjusted to the user's anatomy, which can increase comfort and user acceptance. According to at least one embodiment, the user device can include a data processing unit that can be connected to a data transmission unit for data exchange. The data processing unit can perform complex calculations and analyses to optimize the efficiency and precision of drug delivery. The data processing unit can be a computer unit, specifically a CPU. The connection to the data transmission unit ensures that the processed data can be transmitted quickly and reliably to the control unit of the intraoral device.This seamless communication enables control commands to be adjusted and executed in real time, leading to more precise control of drug delivery. The data processing unit can implement pattern recognition and prediction algorithms to optimize drug delivery, for example, based on historical data and current measurements. This can lead to personalized and needs-based treatment, increasing therapy effectiveness and minimizing potential side effects.

[0088] According to at least one embodiment, the user device can include a microphone and / or a loudspeaker. These additional components can enable enhanced interaction between the user and the intraoral device. The microphone can be used to capture the user's voice commands, which can then be transmitted to the control unit of the intraoral device via the data transmission unit and the radio interface. This can offer the advantage that the user can control the drug delivery by simple voice commands without having to perform any manual intervention, which can be particularly useful, for example, in situations where the user's hands are occupied or a quick response is required. The loudspeaker can be used to transmit acoustic feedback or warnings to the user.This could be, for example, confirmation that a voice command has been successfully received and executed, or a warning that the medication container needs refilling. Integrating a microphone and speaker into the user device thus enables bidirectional communication, which can significantly improve the usability and interactivity of the intraoral device. Using voice commands makes operating the device more intuitive and user-friendly, which can increase user acceptance and satisfaction. Furthermore, the acoustic feedback from the speaker can help increase application safety by immediately informing the user about the status of the intraoral device. These communication mechanisms can be advantageous, for example, in medical applications where precise and timely drug delivery is crucial.The ability to control the intraoral device via voice commands can also increase the accessibility of the device by making it more accessible to users with limited manual dexterity or visual acuity.

[0089] In at least one embodiment, the user device may include a display unit. The display unit may be configured to provide the user with visual information related to the function of the intraoral device. The display unit may show various types of information, such as the drug delivery status, warnings, battery level, or other relevant data that may be of interest to the user. Integrating a display unit into the user device can offer the advantage of providing the user with real-time information about the operating status and functionality of the intraoral device. This can improve the usability and safety of the application, as the user can be immediately alerted to any problems or necessary actions. The display unit may also include interactive functions, such as…The ability to change settings or enter specific commands further enhances the flexibility and adaptability of the intraoral device. Furthermore, the display unit can be implemented in various formats and technologies, including LCD, OLED, or E-Ink, to meet diverse needs and preferences. Visual feedback from the display unit can also optimize drug delivery efficiency by ensuring the user is always informed of the current status and can react accordingly. Such an arrangement can be particularly advantageous in medical applications where precise and reliable information about drug delivery can be crucial.The ability to transmit visual information directly to the user can also reduce the need for additional external devices or interfaces, which can decrease the overall complexity and cost of the setup.

[0090] According to at least one embodiment, the user device can include a communication unit for exchanging data with an end device. The communication unit can support various wireless communication protocols such as Bluetooth, WLAN, NFC, LTE, GSM, narrowband IoT, Zigbee, ANT+, or the like to enable a seamless connection between the user device and the end device. The end device can be an external device, such as a smartphone, tablet, computer, and / or server. By integrating such a communication unit, the user device can also receive updates and configuration changes without requiring a physical connection. This can significantly improve usability and increase the flexibility in using the intraoral device.Furthermore, the communication unit can be used to send diagnostic data and usage statistics to the end device, enabling continuous monitoring and analysis of the effectiveness and condition of the intraoral device. This can be particularly beneficial for medical applications, as it allows for precise therapy monitoring and rapid adaptation to changing conditions. The ability to pair the user device with an end device can also facilitate integration into existing healthcare systems and electronic health records, further improving the efficiency and accuracy of medical care. The communication unit also offers the advantage of bidirectional communication, allowing data to be both sent and received. This can further enhance the interactivity and adaptability of the intraoral device.For example, the user device can automatically make adjustments based on the received data to optimize drug delivery or control the stimulation unit according to the user's individual needs. Overall, integrating a communication unit into the user device can significantly expand the functionality and versatility of the entire setup, thus making a significant contribution to improving therapeutic efficacy and user satisfaction.

[0091] BRIEF DESCRIPTION OF THE FIGURES

[0092] The invention is further explained using the following exemplary figures.

[0093] Figure 1 shows an exemplary embodiment of an intraoral device that is arranged in the interior of the mouth.

[0094] Figure 2 shows an exemplary embodiment of an intraoral device, wherein a nerve stimulation unit can stimulate different areas of the oral cavity to simulate different tastes. Figure 3 shows another exemplary embodiment of an intraoral device arranged within the oral cavity.

[0095] Figure 4 shows one embodiment of an arrangement comprising a user device and an intraoral device.

[0096] DETAILED DESCRIPTION OF THE EXECUTION FORMS

[0097] The embodiments shown in and / or described with reference to the figures are merely examples. The invention is not necessarily limited to the embodiments and / or features shown in and / or described with reference to the figures. Embodiments shown in and / or described with reference to the figures can be combined with one another without the combination necessarily having to include every feature of the respective combined embodiments.

[0098] Figure 1 shows a schematic representation of an intraoral device 100 in the oral cavity 110. The intraoral device 100 can be arranged on a tongue 120.

[0099] The embodiment of an intraoral device 100 shown in Figure 1 may have one, several, or all of the features and / or advantages of an intraoral device 100 according to the present disclosure, even if these are not necessarily explicitly described below or shown in Figure 1. Not all features need to be shown in Figure 1. The embodiment shown in Figure 1 may not include features shown in Figure 2. One, several, or all of the features shown in Figure 1 and / or described below may, but need not, be essential to the invention. One, several, or all of the features may be optional.

[0100] The intraoral device 100 may include a drug container 3. The drug container 3 may serve to hold a drug. The intraoral device 100 may have a drug delivery unit 6. The drug delivery unit 6 may be configured to deliver a drug contained in the drug container 3. The intraoral device 100 may have a nerve stimulation unit 4. The nerve stimulation unit 4 may be configured to stimulate a nerve, a nerve ending, and / or a muscle.

[0101] The intraoral device 100 can have at least one sensor 7. The sensor 7 can be configured to acquire measurements on, in or near the oral cavity 110.

[0102] The intraoral device 100 can include a control unit 2. The control unit 2 can be configured to control the drug delivery unit 6. Alternatively or additionally, the control unit 2 can control the nerve stimulation unit 4. Alternatively or additionally, the control unit 2 can be configured to receive measured values ​​and / or data from the sensor 7.

[0103] In some embodiments, the control unit 2 can control the drug delivery unit 6 and / or the nerve stimulation unit 4 taking into account measured values ​​received from at least one sensor 7.

[0104] The intraoral device 100 can have a radio interface 5. The radio interface 5 can be connected to the control unit 2 for data exchange. The radio interface 5 can receive control commands and transmit them to the control unit 2. The radio interface 5 can exchange data with an external device, for example, receive data from the external device and / or transmit it to the external device. The external device can, for example, be or include a user device 200. Alternatively or additionally, the external device can be or include an end device. Alternatively or additionally, the external device can be a mobile device, e.g., a smartphone or tablet, a computer, and / or a server. The radio interface 5 can be configured to exchange data wirelessly.

[0105] The intraoral device 100 can be a foil or have a foil component. Alternatively, the intraoral device 100 can be foil-shaped. The intraoral device 100 can include a dental splint 16 or have a dental splint 16 component.

[0106] The intraoral device 100 can have at least one sensor 7. A sensor 7 can be integrated into the intraoral device 100. The sensor 7 can be connected to the control unit 2 and / or the radio interface 5 for data exchange. The sensor 7 can be a pressure sensor 21. The intraoral device 100 can be configured to have a pressure sensor 21. The pressure sensor 21 can be configured to detect tongue contact and / or a closing contact of the oral cavity 110.

[0107] Alternatively or additionally, the sensor 7 can be a contact sensor 17, or have a contact sensor 17. The intraoral device 100 may be provided with a contact sensor 17. The contact sensor 17 may be configured to detect a closing contact of the oral cavity 110.

[0108] Alternatively or additionally, the sensor 7 can be a temperature sensor 9, or may include a temperature sensor 9. The intraoral device 100 may be provided with a temperature sensor 9. The temperature sensor 9 may be configured to detect the temperature of the oral cavity 110.

[0109] Alternatively or additionally, the sensor 7 can be a motion sensor, or may include a motion sensor. The intraoral device 100 may be provided with a motion sensor. The motion sensor may be configured to detect movement of the tongue 120 within the oral cavity 110.

[0110] Alternatively or additionally, the sensor 7 can be a flow sensor, or may include a flow sensor. The intraoral device 100 may be provided with a flow sensor. The flow sensor may be configured to detect a fluid flow and / or an air flow in the oral cavity 110.

[0111] The intraoral device 100 can include a camera 8. The camera 8 can be configured to detect mouth movement, lip movement and / or tongue movement.

[0112] The intraoral device 100 may include a nerve stimulation unit 4. The nerve stimulation unit 4 may be configured to stimulate a nerve or a muscle. For example, a nerve, nerve ending, and / or a muscle may be stimulated by an electrical current, which may be delivered to or into tissue via an electrode of the intraoral device 100 and / or the nerve stimulation unit 4. The nerve stimulation unit 4 may be configured to stimulate one or more nerves of the tongue 120. The nerve stimulation unit 4 may be configured to produce and / or simulate a taste by nerve stimulation. Alternatively or additionally, the nerve stimulation unit 4 may be configured to alleviate pain by nerve stimulation. The nerve stimulation unit 4 may be controlled by the control unit 2.

[0113] The drug delivery unit 6 may include a membrane. The membrane may be fluidically connected to the drug container 3 and / or arranged within the drug container 3. The drug delivery unit 6 may include a membrane adjustment unit. The membrane adjustment unit may be configured to adjust the permeability of the membrane for the drug contained in the drug container 3. The membrane may be a semipermeable membrane. The membrane may be configured to allow the drug to pass through at least partially in at least one state and / or operating point of the membrane, and to retain at least one other substance.

[0114] The intraoral device 100 may be provided with an active ingredient outlet through which the active ingredient can be dispensed and / or exit the device. In some embodiments, the active ingredient outlet, when the intraoral device 100 is positioned in the oral cavity 110, may contact a tissue of the oral cavity 110, for example, skin and / or mucous membrane. The drug delivery unit 6 may be configured to transport and / or draw active ingredient from the drug container through the drug delivery outlet.

[0115] The active ingredient reservoir 3 can be fluidically connected to the active ingredient outlet. In some embodiments, the membrane can be fluidically arranged between the active ingredient outlet and the active ingredient reservoir 3. It can be provided that the active ingredient must flow through the membrane when it is transported from the active ingredient reservoir 3 to the active ingredient outlet. In some embodiments, the active ingredient reservoir 3 can include the active ingredient outlet. The membrane adjustment unit can be configured to adjust the membrane temperature. The permeability of the membrane can be temperature-dependent and / or dependent on the membrane temperature. The permeability of the membrane with respect to the active ingredient can be temperature-dependent and / or dependent on the membrane temperature. The membrane adjustment unit can, for example, include a temperature adjustment unit, such as a heating coil, that can adjust the membrane temperature.

[0116] Alternatively or additionally, the membrane adjustment unit can be configured to generate an electromagnetic field acting on the membrane. The membrane's permeability can be adjusted by, and / or depend on, the electromagnetic field. The membrane's permeability with respect to the active ingredient can also be adjusted by, and / or depend on, the electromagnetic field. The electromagnetic field can be generated, for example, by an electrode and / or coil of the membrane adjustment unit and / or the drug delivery unit.

[0117] The drug delivery unit 6 may include a sealing film. This sealing film may be fluidically connected to the drug container 3 and / or the membrane. The sealing film may close the drug container 3 and / or the drug outlet. The sealing film may be designed to dissolve, at least partially, when the intraoral device 100 is inserted into the oral cavity 110. Alternatively or additionally, the sealing film may be removed before the intraoral device 100 is positioned in the oral cavity 110.

[0118] The intraoral device 100 may have one or more electrodes. For example, the drug delivery unit 6 may include at least one electrode. For example, the nerve stimulation unit 4 may include at least one electrode. If the intraoral device 100 has a drug delivery unit 6 and a nerve stimulation unit 4, it may be provided that at least one, several, or all electrodes of the drug delivery unit 6 and at least one, several, or all electrodes of the nerve stimulation unit 4 are different from each other.

[0119] The drug delivery unit 6 may comprise at least one electrode and / or coil. The electrode, e.g., an electrode of the drug delivery unit, may in some embodiments be configured to contact skin and / or mucous membrane when an intraoral device 100 is inserted into the oral cavity 110. The electrode may be configured to conduct an electric current and / or generate an electric field. Alternatively or additionally, the drug delivery unit 6 may have a coil that can generate an electric field and / or an electromagnetic field, and / or may be used in generating an electric field and / or an electromagnetic field.

[0120] The drug delivery unit 6 can be configured to perform iontophoresis and / or to introduce the drug by iontophoresis. An ionized drug can be introduced from the drug container 3 into the skin and / or mucous membrane.

[0121] The drug delivery unit 6 can comprise a cathode and an anode. The drug delivery unit 6 can be configured to generate an electric field. For example, an electric field can be generated when current flows between the cathode and the anode. For example, an ionized drug can be transported due to the current flowing between the cathode and the anode. The electric field can increase the permeability of a cell membrane, skin, and / or mucous membrane of the oral cavity 110. A drug contained in the drug reservoir 3 can penetrate the cell membrane, mucous membrane, and / or skin.

[0122] The drug delivery unit 6 can alternatively or additionally be configured to perform an electrical operation and / or to introduce the drug by electrical operation.

[0123] The drug delivery unit 6 can be configured to generate an electric field, for example, with an electrode and / or coil. An electric pulse may be generated during the generation of the electric field. The drug delivery unit 6 can be configured to open a pore in the cell membrane, mucous membrane, and / or skin. For example, the pore may be opened, at least temporarily, by the electric pulse. The drug can then penetrate through or into the pore.

[0124] The drug delivery unit 6 can be configured to perform sonophoresis and / or introduce the drug by sonophoresis.

[0125] The drug delivery unit 6 may include a sound generator. The drug delivery unit 6 may be configured to generate sound waves. The sound waves may preferably be ultrasound. Cavitation and / or a bubble may be created in the drug. The permeability of a cell membrane, skin, and / or mucous membrane of the oral cavity 110 may be increased by the cavitation, thus enabling more efficient absorption of the drug. The sound waves may be applied to the skin and / or mucous membrane of the oral cavity 110, which may generate vibrations and / or cause the corresponding tissue to vibrate, further improving the absorption of the drug.

[0126] Figure 2 shows an intraoral device 100 arranged in an oral cavity 110. The intraoral device 100 can be placed on the tongue 120. The tongue 120 can be divided into different regions, including the first tongue region 120.1, the second tongue region 120.2, the third tongue region 120.3, the fourth tongue region 120.4, and the fifth tongue region 120.5.

[0127] The embodiment of an intraoral device 100 shown in Figure 2 may have one, several, or all of the features and / or advantages of an intraoral device 100 according to the present disclosure, even if these are not necessarily explicitly described below or shown in Figure 2. Not all features need to be shown in Figure 2. The embodiment shown in Figure 2 may include features not shown in Figure 2. One, several, or all of the features shown in Figure 2 and / or the features described below may, but need not, be essential to the invention. One, several, or all of the features may be optional and / or facultative.

[0128] As exemplified in Figure 2, the intraoral device 1 and / or the nerve stimulation unit 4 can be designed to stimulate nerves, nerve endings and / or muscles of various areas in the oral cavity, e.g. tongue areas, e.g. tongue areas 120.1, 120.2, 120.3, 120.4, 120.5.

[0129] In some embodiments, it may be provided that, for example, a taste that can be or may be simulated by stimulation can be assigned to a specific tongue area. For example, it may be provided that the intraoral device 1 and / or the nerve stimulation unit 4 can be configured to simulate a sour taste in a first tongue area 120.1 by stimulating nerves in the first tongue area 120.1, as indicated, for example, by the jagged arrows and the lemon in Figure 2. For example, it may be provided that the intraoral device 1 and / or the nerve stimulation unit 4 can be configured to simulate an umami taste in a second tongue area 120.2 by stimulating nerves in the second tongue area 120.2, as indicated, for example, by the jagged arrows and the tomato in Figure 2.

[0130] For example, the intraoral device 1 and / or the nerve stimulation unit 4 may be configured to simulate a salty taste in a third tongue area 120.3 by stimulating nerves in the third tongue area 120.3, as indicated, for example, by the jagged arrows and the salt in Figure 2.

[0131] For example, the intraoral device 1 and / or the nerve stimulation unit 4 may be configured to simulate a sweet taste in a fourth tongue area 120.4 by stimulating nerves in the fourth tongue area 120.4, as indicated, for example, by the jagged arrows and the candy in Figure 2.

[0132] For example, the intraoral device 1 and / or the nerve stimulation unit 4 may be configured to simulate a spicy taste in a fifth tongue area 120.5 by stimulating nerves in the fifth tongue area 120.5, as indicated, for example, by the jagged arrows and the chili pepper in Figure 2.

[0133] Alternatively or additionally, it may be provided that the intraoral device 1 and / or the nerve stimulation unit 4 can stimulate different areas in the oral cavity, e.g. tongue areas, e.g. tongue areas 120.1, 120.2, 120.3, 120.4, 120.5, in order to, for example, relieve pain.

[0134] Figure 3 shows an intraoral device 100 arranged in an oral cavity 110. The intraoral device 100 may include a dental splint 16. The dental splint 16 may be configured to rest on the teeth of the upper and lower jaw.

[0135] The embodiment of an intraoral device 100 shown in Figure 3 may have one, several, or all of the features and / or advantages of an intraoral device 100 according to the present disclosure, even if these are not necessarily explicitly described below or shown in Figure 3. Not all features need to be shown in Figure 3. The embodiment shown in Figure 3 may include features not shown in Figure 3. One, several, or all of the features shown in Figure 3 and / or described below may, but need not, be essential to the invention. One, several, or all of the features may be optional.

[0136] In some embodiments, the intraoral device 100 shown in Figure 3 may differ from an embodiment shown in and / or described with reference to Figure 1 only in that the intraoral device 100 has a toothed rail 16 instead of a foil 1. In some embodiments, the intraoral device 100 shown in Figure 3 may differ from an embodiment shown in and / or described with reference to Figure 1 by the absence of at least one feature. In some embodiments, the intraoral device 100 shown in Figure 3 may differ from an embodiment shown in and / or described with reference to Figure 1 by at least one added feature.

[0137] The intraoral device 100 can include a drug container 3. The drug container 3 can serve to hold a drug. The intraoral device 100 can further comprise a drug delivery unit 6. The drug delivery unit 6 can be configured to deliver the drug contained in the drug container 3.

[0138] The intraoral device 100 may include a nerve stimulation unit 4. The nerve stimulation unit 4 may be configured to stimulate a nerve, a nerve ending and / or a muscle.

[0139] The intraoral device 100 can have at least one sensor 7. The sensor 7 can be configured to acquire measurements on, in or near the oral cavity 110.

[0140] The intraoral device 100 can include a control unit 2. The control unit 2 can control the drug delivery unit 6. The control unit 2 can control the nerve stimulation unit 4. A radio interface 5 can be connected to the control unit 2 for data exchange. The radio interface 5 can be configured to receive control commands and transmit them to the control unit 2. The radio interface 5 can exchange data with an external device, for example, receive data from the external device and / or transmit data to the external device. In some embodiments, the control unit 2 can control the drug delivery unit 6 and / or the nerve stimulation unit 4 taking into account measured values ​​received from at least one sensor 7.

[0141] The intraoral device 100 can have at least one sensor 7. The sensor 7 can be connected to the control unit 2 and / or the radio interface 5 for data exchange. The sensor 7 can be a pressure sensor 21. The pressure sensor 21 can be configured to detect tongue contact and / or a closing contact of the oral cavity 110.

[0142] Alternatively or additionally, the intraoral device 100 can include a nerve stimulation unit 4. The nerve stimulation unit 4 can be configured to stimulate a nerve and / or a muscle. The nerve stimulation unit 4 can be controlled by the control unit 2.

[0143] The intraoral device 100 can include a camera 8. The camera 8 can be configured to detect mouth movement, lip movement, and / or tongue movement. The camera 8 can be connected to the control unit 2 for data exchange.

[0144] The intraoral device 100 can include a membrane 17. The membrane 17 can be fluidically connected to the drug container 3 and / or arranged within the drug container 3. A membrane adjustment unit can adjust the permeability of the membrane 17 to the drug contained in the drug container 3.

[0145] The intraoral device 100 may have a sealing film 19. The sealing film 19 may close the drug container 3. The sealing film 19 may be designed to dissolve, at least partially, when the intraoral device 100 is inserted into the oral cavity 110.

[0146] Figure 4 shows an arrangement 300 comprising a user device 200. The arrangement 300 includes an intraoral device 100 (not shown in Figure 4). The arrangement 300 and / or the intraoral device 100 may have one, several, or all of the features and / or advantages of an intraoral device 100 according to the present disclosure, even if these are not necessarily explicitly described below or shown in Figure 4. Not all features need to be shown in Figure 4. The embodiment shown in Figure 4 may include features not shown in Figure 4. One, several, or all of the features shown in Figure 4 and / or described below may, but need not, be essential to the invention. One, several, or all of the features may be optional.

[0147] The user device 200 can have a mounting tuning band 25. The mounting tuning band 25 can be configured to attach the user device 200 to a head.

[0148] The user device 200 can include an energy storage device 26. The energy storage device 26 can be configured to provide electrical energy to the user device 200.

[0149] The user device 200 may include a data processing unit 27. The data processing unit 27 may be configured to process data, e.g., data received by the user device 200. The data processing unit 27 may be or include a computer unit. The data processing unit 27 may comprise one or more CPUs, microcontrollers, integrated circuits, FPGAs, or the like.

[0150] The user device 200 can include a data transmission unit 28. The data transmission unit 28 can be configured to transmit data wirelessly. The data transmission unit 28 can be configured to exchange data with the radio interface 5 of the intraoral device 100. The data processing unit 27 can be connected to the data transmission unit 28 for data exchange.

[0151] The data transmission unit 28 can be configured to receive and / or send data via, for example, Bluetooth, NFC, LTE, narrowband-IoT, GSM, WLAN, ANT+, ZigBee or another suitable protocol.

[0152] The data processing unit 27 may be able to create, modify, and / or change a control command. The control command may be transmitted via the data transmission unit 28 to the radio interface 5 of the intraoral device 100.

[0153] The data processing unit 27 may be able to receive data, such as information, measurement data, condition data, status data, warnings, diagnoses, or the like, from the intraoral device 100 via the radio interface 5 and the data transmission unit 28. The data processing unit 27 may be able to process, combine, aggregate, and / or manipulate the received data. The data processing unit 27 may also be able to generate further data based on the received data, such as information, control commands, condition data, status data, warnings, diagnoses, or the like.

[0154] The user device 200 may include a loudspeaker 29. The loudspeaker 29 may be configured to emit acoustic signals. The loudspeaker 29 may be connected to the data processing unit 27 for data exchange. The data processing unit 27 may be able to communicate and / or convey an instruction, directive, information, warning, status message, diagnosis, or the like via the loudspeaker 29.

[0155] The user device 200 may include a communication unit 30. The communication unit 30 may be configured to exchange data with an external device and / or terminal. The communication unit 30 may be connected to the data processing unit 27 for data exchange. The communication unit 30 may be combined with and / or identical to the data transmission unit 28. Alternatively, the data transmission unit 28 and the communication unit 30 may be different units. The data processing unit 27 may be able to exchange data with the external device and / or terminal via the communication unit 30. The external device and / or terminal may, for example, be a mobile device, such as a smartphone or tablet, and / or a computer and / or server.For example, this could enable or allow remote control and / or remote maintenance of the intraoral device. For example, this could enable or allow remote diagnosis and / or telemedicine.

[0156] The communication unit 30 can be configured to exchange data wirelessly. The communication unit 30 can be configured to receive and / or send data via, for example, Bluetooth, NFC, LTE, narrowband IoT, GSM, WLAN, ANT+, ZigBee, or another suitable protocol. The user device 200 can have a microphone 32. The microphone 32 can be configured to record acoustic signals. The microphone 32 can be connected to the data processing unit 27 for data exchange. It can be provided that the data processing unit 27 can receive instructions and / or control commands from a user via the microphone 32.

[0157] The user device 200 can include a frame 33. The frame 33 can be configured to carry and support the various components of the user device 200.

[0158] The user device 200 can include an odor transponder. The odor transponder 34 can be configured to generate or simulate odors. The odor transponder 34 can be connected to the data processing unit 27 for data exchange. The data processing unit 27 can be configured to receive data and / or measurements acquired by the odor transponder 35. The data processing unit 27 can be configured to control the odor transponder 35 to emit an odor.

[0159] The user device 200 can include a display unit 35. The display unit 35 can be configured to display visual information. The display unit 35 can be connected to the data processing unit 27 for data exchange. It can be provided that the data processing unit 27 can display and / or communicate information, control commands, condition data, status data, warnings, diagnoses, or the like to a user via the display unit 35, for example, but not necessarily to the intraoral device 100.

[0160] The features shown in the claims, the description and / or the figures may be essential, individually or in combination, for the realization of the invention. List of reference numerals

[0161] : Slide

[0162] : Control unit

[0163] : Active ingredient container

[0164] : Nerve stimulation unit

[0165] : Wireless interface

[0166] : Drug delivery unit

[0167] : Sensor

[0168] Camera

[0169] : Temperature sensor

[0170] 6: Dental splint

[0171] 7: Contact sensor

[0172] 9: Sealing foil

[0173] 1: Pressure sensor

[0174] 5: Attachment strap

[0175] 6: Energy storage

[0176] 7: Data processing unit

[0177] 8: Data transmission unit

[0178] 9: Speakers

[0179] 0: Communication unit

[0180] 2: Microphone

[0181] 3: Frame

[0182] 4: Odor transponder

[0183] 5: Display

[0184] 00: Intraoral device

[0185] 10: Inside of the mouth

[0186] 20: Tongue

[0187] 20.1: first tongue area

[0188] 20.2: second tongue area

[0189] 20.3: third tongue area

[0190] 20.4: fourth tongue region .5: fifth tongue region

[0191] : User device : Arrangement

Claims

Claims:

1. Intraoral device (too) for placement in the oral cavity (no), comprising an active ingredient container (3) for holding an active ingredient, an active ingredient delivery unit (6) configured to deliver an active ingredient contained in the active ingredient container (3), and a control unit (2) configured to control the active ingredient delivery unit (6), wherein the intraoral device (100) has a radio interface (5) connected to the control unit (2) for data exchange, wherein the radio interface (5) is configured to receive control commands and transmit them to the control unit (2).

2. Intraoral device (100) according to claim 1, wherein the intraoral device (100) is or comprises a film (1), and / or wherein the intraoral device (100) is film-shaped.

3. Intraoral device (100) according to claim 1 or 2, wherein the intraoral device (100) is configured to be arranged on a tongue (120) in the oral cavity (110).

4. Intraoral device (100) according to any of the preceding claims, wherein the intraoral device (100) is or comprises a toothed splint (16).

5. Intraoral device (100) according to one of the preceding claims, wherein the intraoral device (100) has at least one sensor (7) which is connected to the control unit (2) and / or the radio interface (5) for data exchange.

6. Intraoral device (100) according to claim 5, wherein the sensor (7) has a pressure sensor (21) or is a pressure sensor (21), wherein preferably the pressure sensor (21) is configured to detect tongue contact and / or a closing contact of the oral cavity (110) when the intraoral device (100) is received in the oral cavity (110).

7. Intraoral device (100) according to claim 5 or 6, wherein the sensor (7) comprises a pH sensor or is a pH sensor, preferably the pH sensor being configured to measure the pH value of the oral cavity (110) and / or in the to capture the oral cavity (no) when the intraoral device (100) is received in the oral cavity (110).

8. Intraoral device (too) according to any one of the preceding claims 5 to 7, wherein the sensor (7) has a contact sensor (17) or is a contact sensor (17), wherein preferably the contact sensor (17) is configured to detect a closing contact of the oral cavity (110) when the intraoral device (100) is received in the oral cavity (110).

9. Intraoral device (100) according to any one of the preceding claims 5 to 8, wherein the sensor (7) has a temperature sensor (9) or is a temperature sensor (9), wherein preferably the temperature sensor (9) is configured to detect a temperature of the oral cavity (110) when the intraoral device (100) is placed in the oral cavity (110).

10. Intraoral device (100) according to any one of the preceding claims 5 to 9, wherein the sensor (7) has a motion sensor or is a motion sensor, wherein preferably the motion sensor is configured to detect a movement of a tongue (120) in the oral cavity (110) when the intraoral device (100) is received in the oral cavity (110).

11. Intraoral device (100) according to any one of the preceding claims 5 to 10, wherein the sensor (7) has a flow sensor or is a flow sensor, wherein preferably the flow sensor is configured to detect a fluid flow and / or an air flow in the oral cavity (110) when the intraoral device (100) is received in the oral cavity (110).

12. Intraoral device (100) according to one of the preceding claims, wherein the intraoral device (100) has a camera (8), wherein the camera (8) is preferably configured to capture one or more movements of the mouth, lip and / or tongue when the intraoral device (100) is placed in the oral cavity (110).

13. Intraoral device (100) according to one of the preceding claims, wherein the intraoral device (100) comprises a nerve stimulation unit (4) configured to stimulate a nerve, in particular a nerve end, and / or a muscle.

14. Intraoral device (100) according to claim 13, wherein the nerve stimulation unit (4) is configured to stimulate one or more nerves of a tongue (120) in the oral cavity (110) when the intraoral device (100) is received in the oral cavity (110).

15. Intraoral device (100) according to claim 13 or 14, wherein the nerve stimulation unit (4) is configured to produce and / or simulate a taste by nerve stimulation.

16. Intraoral device (100) according to any one of the preceding claims 13 to 15, wherein the nerve stimulation unit (4) is configured to relieve pain by nerve stimulation.

17. Intraoral device (100) according to any one of the preceding claims 13 to 16, wherein the nerve stimulation unit (4) is configured to be controlled by the control unit (2).

18. Intraoral device (100) according to one of the preceding claims, wherein the drug delivery unit (6) has a membrane which is fluidically connected to the drug container (3) and / or is arranged in the drug container (3).

19. Intraoral device (100) according to claim 18, wherein the drug delivery unit (6) has a membrane adjustment unit configured to adjust the permeability of the membrane for the drug contained in the drug container (3).

20. Intraoral device (100) according to claim 19, wherein the membrane adjustment unit is configured to adjust the temperature of the membrane, wherein the permeability of the membrane is dependent on the temperature.

21. Intraoral device (100) according to claim 19 or 20 wherein the membrane adjustment unit is configured to generate an electromagnetic field acting on the membrane, wherein the permeability is adjustable by the electromagnetic field.

22. Intraoral device (100) according to one of the preceding claims, wherein the drug delivery unit (6) has a sealing film (19) which is fluidically connected to the drug container (3) and / or the membrane, and / or which seals the drug container (3), wherein preferably the sealing film (19) is designed to dissolve at least partially when the intraoral device (100) is inserted into the oral cavity (110).

23. Intraoral device (100) according to one of the preceding claims, wherein the drug delivery unit (6) has at least one electrode which is configured to contact skin and / or mucous membrane when the intraoral device (100) is inserted into the oral cavity (110).

24. Intraoral device (100) according to claim 23, wherein the electrode is configured to conduct an electric current to generate an electric field and to introduce an ionized active ingredient from the active ingredient container (3) into the skin and / or mucous membrane.

25. Intraoral device (100) according to claim 23 or 24, wherein the drug delivery unit (6) has a cathode and an anode.

26. Intraoral device (100) according to one of the preceding claims, wherein the drug delivery unit (6) is configured to generate an electric field and to increase the permeability of a cell membrane, skin and / or mucous membrane of the oral cavity (110) through the electric field, so that an active ingredient contained in the drug container (3) can penetrate into the cell membrane, mucous membrane and / or skin.

27. Intraoral device (100) according to claim 26, wherein the drug delivery unit (6) is configured to generate an electric pulse when generating the electric field.

28. Intraoral device (100) according to claim 26 or 27, wherein the drug delivery unit (6) is configured to open a pore of the cell membrane, mucous membrane and / or skin so that the drug can penetrate through or into the pore.

29. Intraoral device (100) according to one of the preceding claims, wherein the drug delivery unit (6) is configured to generate sound waves, preferably ultrasound, so that cavitation and / or a bubble is generated in the drug and the permeability of a cell membrane, skin and / or mucous membrane of the oral cavity (110) is increased.

30. Intraoral device (100) according to claim 29, wherein the sound waves are applied to the skin and / or mucous membrane of the oral cavity (110) so that the skin and / or mucous membrane vibrates.

31. Arrangement (300) comprising an intraoral device (100) according to one of the preceding claims and a user device (200), wherein the user device (200) comprises a data transmission unit (28) which is configured for wireless data exchange with the radio interface (5).

32. Arrangement (300) according to claim 31, wherein the user device (200) is or comprises a head device which is configured to be arranged and / or attached to a head.

33. Arrangement (300) according to claim 31 or 32, wherein the user device (200) has a data processing unit (27) which is connected to the data transmission unit (28) for data exchange.

34. Arrangement (300) according to any one of the preceding claims 31 to 33, wherein the user device (200) comprises a microphone and / or a loudspeaker (29).

35. Arrangement (300) according to any one of the preceding claims 31 to 34, wherein the user device (200) comprises a display unit.

36. Arrangement (300) according to any one of the preceding claims 31 to 35, wherein the user device (200) has a communication unit (30) for data exchange with an end device.

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