Microfluidic droplet apparatus and method

The droplet transfer module addresses inefficiencies in traditional multiwell systems by integrating droplet microfluidics for precise, scalable, and waste-reducing high-throughput screening.

WO2026115251A1PCT designated stage Publication Date: 2026-06-04ASSUREDROP LTD

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
ASSUREDROP LTD
Filing Date
2025-11-25
Publication Date
2026-06-04

AI Technical Summary

Technical Problem

Traditional multiwell substrate systems face inefficiencies due to large reagent volumes and variability introduced by manual pipetting, limiting scalability and accuracy in high-throughput screening.

Method used

A droplet transfer module integrated with multiwell substrates for precise manipulation of small sample volumes using droplet microfluidics, enabling efficient, scalable, and waste-reducing high-throughput screening.

Benefits of technology

Enables precise droplet handling and parallel testing with minimal sample and reagent use, reducing plastic waste and operational costs while supporting complex sample arrays and workflows.

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Abstract

Microfluidic Droplet Apparatus and Method Disclosed is a droplet transfer module configured to engage a multiwell substrate. The DTM comprises: transfer face; at least one primary channel; secondary channel portion at the transfer face, configured to form at least one secondary channel when the droplet transfer module is engaged with the MWP, comprising at least one secondary channel access portion to permit flow of droplet fluid in the secondary channel portion; and at least one transfer channel connected between the primary channel and the transfer face, the at least one transfer channel comprising: first transfer channel connection portion connected to the primary channel, configured to receive a droplet from the droplet fluid in the primary channel; and second transfer channel connection portion located at the transfer face and connected to the secondary channel portion, configured to allow exit of a droplet from transfer channel to corresponding well of the multiwell substrate engaged with the DTM.
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