1 results about "Amidinotransferases" patented technology

The application relates to the field of biological medicine, and discloses a use of indole-3-propionic acid in preparation of a medicine for preventing and treating acute-on-chronic liver failure. Experiments prove that the indole-3-propionic acid can effectively inhibit the formation of neutrophil-related extracellular traps, reduce the levels of alanine aminotransferase, aspartate aminotransferase, total bilirubin and inflammatory factors TNF-alpha, IL-6 and IL-1beta related to acute-on-chronic liver failure, reduce liver tissue necrosis and inflammatory infiltration, and improve the survival rate. Therefore, the indole-3-propionic acid can be used for preparing a medicine for preventing and / or treating acute-on-chronic liver failure, and provides a new small-molecule intervention strategy for acute-on-chronic liver failure.