307 results about "Ammonium acetate" patented technology

The invention discloses a polybenzimidazole modified ion exchange membrane as well as preparation and application thereof. The polybenzimidazole modified ion exchange membrane comprises a polybenzimidazole-containing porous base membrane, the surface of the porous base membrane is grafted with a sulfonic acid modified layer, and the outer surface of the sulfonic acid modified layer is coated with an aluminum fluoride layer. The preparation method of the membrane comprises the following steps: immersing a polybenzimidazole-based membrane into an ammonium acetate aqueous solution for reaction, taking out the base membrane after the reaction, and drying to obtain a pretreated base membrane; immersing the pretreated base membrane into a sulfonic acid group grafting solution, heating for reaction, cleaning the base membrane after the reaction, and drying to obtain a sulfonic acid modified base membrane; and immersing the sulfonic acid modified base membrane into an ethanol solution of aluminum fluoride for reaction, taking out the membrane after the reaction, cleaning and drying to obtain the membrane. The membrane can be used for assembling a flow battery. According to the invention, the problem that a sulfonic acid modified layer is incompatible with metal fluoride is overcome, and a proper combination of a sulfonating agent and metal fluoride is screened, so that the high-performance ion exchange membrane which can be used for a flow battery is successfully obtained.

The present invention discloses a platinum electroplating solution, a preparation method thereof and an application in semiconductors, which comprises the following raw materials: 0.5-10 g / L of platinum salt PEP, 15-35 g / L of ethylenediamine sulfate, 5.0-29 g / L of malonic acid, 5.0-40 g / L of ammonium acetate, the balance being ultrapure water and ammonia water; the pH value of the platinum electroplating solution is adjusted to 7.0 with ammonia water; the method for preparing the coating comprises the following steps: S1, degreasing and pickling the semiconductor device to be processed; S2, selecting corresponding electroplating conditions and configuring a corresponding anode and its anode mask; S3, performing electroplating; S4, automatically adding the platinum salt PEP solution in a linked manner; S5, adjusting the pH value of the platinum electroplating solution; S6, stopping electroplating after reaching the target coating thickness or the preset electroplating time. The platinum metal film formed by the present invention has excellent morphology, uniform distribution, high wear resistance and excellent compactness.

The present invention relates to the technical field of antibiotic production, and in particular to a dalbavancin intermediate A40926 and a separation and purification method thereof, comprising the following steps: S1, filtering a fermentation broth containing the dalbavancin intermediate A40926 to obtain a collected liquid; S2, adsorbing the collected liquid through a macroporous adsorption resin, eluting with ethanol, and collecting an eluate a having an A40926 unit greater than 100 mg / L; S3, ultrafiltrating and concentrating the eluate a to obtain a concentrated liquid having an A40926 unit of 15,000 to 16,000 mg / L; S4, subjecting the concentrated liquid to a chromatography exchange resin, top-washing with pure water, and gradient eluting with an ammonium acetate-ethanol solution, to collect an eluate b having an A40926 purity greater than 95%; S5, adjusting the pH of the eluate b to 8.0±0.2, adding acetone, adjusting the feed liquid temperature to 2 to 8°C, stirring for 6 to 7 hours, performing crystallization, and filtering and drying to obtain the dalbavancin intermediate A40926.

A method for synthesizing mirogabalin besilate. The method comprises the following steps: subjecting a chiral ketene and cyanoacetate to a condensation reaction under the action of ammonium acetate to obtain an unsaturated cyano ester, then subjecting the unsaturated cyano ester and nitromethane to a condensation reaction to obtain a nitro ester, subjecting the nitro ester to high-temperature de-esterification to obtain a chiral nitronitrile, then subjecting same to nitroreduction to obtain a chiral aminonitrile, subsequently hydrolyzing the chiral aminonitrile to obtain a mirogabalin free alkali, and finally salifying the mirogabalin free alkali and benzenesulfonic acid to obtain mirogabalin besilate. In the present invention, a chiral cyclobutane quaternary carbon center is stereoscopically and specifically constructed to obtain a chiral nitro ester having a single stereoscopic configuration, thereby preventing chiral isomer waste generated by chiral isomer resolution, such that chiral column separation or chiral resolution is not required, the production cost is significantly reduced, and the residue of heavy-metal titanium in a product and environmental pollution caused by solid waste heavy-metal titanium are also prevented.

< TableDetails num = '0001' > < Title / > < tbl: tgroup cool = '2' > < tbl: colspec cool = 'c001' cool width = '50%' / > < tbl: colspec cool width = 'c002' cool width = '50%' / > < tbl: cool width = '1' > impurity < / tbl: cool > < tbl: cool width = '1' > HPLC percentage content < / tbl The mobile phase B is a 8mmol / L ammonium acetate solution, and the solvent is a mixed solvent of acetonitrile and water in a volume ratio of 95: 5; and carrying out gradient elution at a flow rate of 1.0 ml / min.

The invention discloses a platinum chemical plating solution and a preparation method and application thereof in semiconductors, the platinum chemical plating solution comprises the following raw materials: 0.5-10.0 g / L of platinum salt PEP, 2.1-10.0 g / L of ethylenediamine sulfate, 1.2-8.9 g / L of malonic acid, 5-50 g / L of ammonium acetate, 1.2-9.2 g / L of thiourea dioxide, and the balance of ultrapure water and ammonia water; and the pH value of the solution is adjusted to 7.0 by ammonia water. The platinum chemical plating solution disclosed by the invention is suitable for nano precision manufacturing and processing on the surface of an electronic element product of a semiconductor device, and a formed platinum metal film has excellent uniform distribution, compactness and high wear resistance; a semiconductor electronic component product with excellent plugging performance, corrosion resistance, high-precision conductivity and high-quality electronic signal transmission performance is obtained.

The invention provides a method for detecting a genotoxic impurity TG707 in a macassavir raw material medicine and an intermediate TG7, and relates to the technical field of medicine detection, and the method comprises the step of detecting the genotoxic impurity TG707 in the macassavir raw material medicine or the intermediate TG7 sample by adopting a high performance liquid chromatography and mass spectrometry combined method, the mobile phase A is an ammonium acetate solution, and the mobile phase B is methanol. By adopting a liquid chromatography-mass spectrometry method and utilizing the selectivity of mass spectrum multi-channel monitoring, main components and impurities enter mass spectrum at the same time, the interference of high-concentration main components on the mass spectrum detection sensitivity is avoided, good separation on the mass spectrum is realized, and the sensitivity is relatively high; an ammonium acetate solution and methanol are used as mobile phases, so that the peak pattern and sensitivity of TG707 are ensured. The technical problems that in the prior art, the peak of TG707 on a liquid phase is between two peaks of a main component TG7, and baseline separation is difficult to achieve by replacing a chromatographic column and optimizing the fluidity gradient are solved.

< TableDetails number = '0001' > < Title / > < tbl: tgroup cool = '2' > < tbl: colspec cool = 'c001' cool = '46%' / > < tbl: colspec cool = 'c002' cool = '54%' / > < tbl: cool > < tbl: cool = '1' > impurity < / tbl: cool > < tbl: cool = '1' > HPLC percentage content < / tbl The mobile phase B is a 8mmol / L ammonium acetate solution, and the solvent is a mixed solvent of acetonitrile and water in a volume ratio of 95: 5; and carrying out gradient elution at a flow rate of 1.0 ml / min.

The invention relates to the technical field of food safety detection, in particular to a method for detecting urea in bean sprouts and application thereof.The method comprises the following steps that smashed bean sprouts are subjected to two times of ultrasonic extraction and centrifugation, supernate is combined, and an extracting solution is obtained; fixing the volume and filtering to obtain a to-be-detected solution; detecting the liquid to be detected by using liquid chromatography-tandem mass spectrometry; an extraction solvent for ultrasonic extraction is a 5% formic acid-acetonitrile composite solution; the conditions of the liquid chromatography-tandem mass spectrometry are as follows: the chromatographic conditions are as follows: a chromatographic column is an HILIC column; the sample size is 10 [mu] L; a mobile phase is a mixed solution of a 0.02 mmol / L ammonium acetate buffer salt solution and acetonitrile, and isocratic elution is carried out; the flow rate is 0.3 mL / min; the column temperature is 40 DEG C; mass spectrum conditions are as follows: an electrospray ionization (ESI) positive ion mode, electrospray voltage of 4000 V, sheath gas pressure of 30 psi, auxiliary gas pressure of 5 psi, capillary heating temperature of 300 DEG C and scanning mode of MRM. The method disclosed by the invention is free from substance interference, high in sensitivity, accurate in result, low in cost and high in efficiency, and can be used as a standard detection method.

The present invention provides a lead-acid battery repair fluid, and its preparation and use methods. The repair fluid comprises the following raw materials: MXene, ammonium acetate, ammonium bicarbonate, sodium ethylenediaminetetraacetate (EDTA), montmorillonite, polymaleic anhydride, sodium polystyrene sulfonate, chloroethyl polyvinylpyridinium salt, polyvinylpyrrolidone (PVP), sodium alginate, and deionized water. The repair fluid can effectively dissolve lead sulfate crystals and form a durable and stable protective film on the electrode plates, thereby regenerating the lead-acid battery while effectively preventing further lead sulfate crystals from adhering to the electrode plates, thereby increasing the battery's service life. Furthermore, the raw materials used in the present invention are safe and harmless to the human body, and the preparation method is simple, efficient, and environmentally friendly.

The invention discloses a method for separating and enriching 24 perfluorinated compounds in a water environment. The method comprises the following steps: collecting a to-be-detected water sample, filtering, and adding an isotope labeled recovery rate indicator to obtain a pretreated water sample; activating a PWAX solid-phase extraction column by using a 0.1% ammonia water methanol solution, methanol and ultrapure water in sequence, and enriching a water sample through the column; leaching the PWAX solid-phase extraction column with a 25 mM ammonium acetate aqueous solution (pH = 4) to remove water-soluble interference impurities; carrying out vacuum freeze drying on the solid-phase extraction column, and eluting with methanol and 0.1% ammonia water methanol solution; and blowing the collected eluent to 200 L under nitrogen flow, adding 1: 1 methanol and aqueous solution into the obtained residue, redissolving to 1.00 mL, filtering with a filter membrane, and putting into a polypropylene sample injection bottle to complete separation and enrichment. The method disclosed by the invention is simple and convenient to operate, can enrich various types of perfluorinated compounds (including carboxylic acids, sulfonic acids, fluorosulfonic acids and the like) in water, and is wide in application range and relatively high in accuracy.

The invention relates to the technical field of detection, in particular to a kit for liquid phase detection of amino acid, a pretreatment method and a liquid phase detection method. The kit comprises a protective agent, an activating solution, a leacheate, an eluent and a resolvent, the protective agent comprises a first ammonium acetate solution; the activating solution comprises methanol and a second ammonium acetate solution; the leacheate comprises a formic acid aqueous solution and methanol; the eluent comprises a methanol solution with the pH value of 9 to 13. The detection method using the kit can meet the requirements of related laws and regulations on linearity, repeatability, batch-to-batch difference, accuracy and the like of cystine, lysine, ornithine and arginine, and has important reference significance for evaluating whether cystinuria exists or not.

The invention relates to the technical field of pharmaceutical analysis, in particular to a detection method of a compound sodium picosulfate oral solution, which is used for detecting sodium picosulfate and related substances. The detection method comprises the following steps: carrying out liquid chromatography detection on the compound sodium picosulfate oral solution; the conditions of the liquid chromatography detection are as follows: (1) a chromatographic column is a reverse C18 chromatographic column or an efficiency equivalent column thereof; (2) taking a mixed solution of an ammonium acetate buffer salt solution and methanol as a mobile phase A and acetonitrile as a mobile phase B; wherein the pH value of the ammonium acetate buffer salt solution is 4.9 to 5.2; and (3) gradient elution is adopted. The quality detection method disclosed by the invention can be used for the preparation process of the compound sodium picosulfate oral solution and the quality control of the final product, is good in specificity, good in separation degree, high in sensitivity and good in reproducibility, and has important significance for evaluating the advantages and disadvantages of synthesis and preparation processes, controlling the quality of the final product and detecting a stable sample.

The invention discloses a phototherapy reagent and a preparation method and application thereof. The preparation method comprises the following steps: 1-[4-(diethylamino) phenyl]-ethane-1-ketone and 4-methoxybenzaldehyde are subjected to a condensation reaction in a NaOH ethanol solution, and a product and nitromethane are subjected to addition; performing condensation and addition on the other groups of raw materials by the same method; cyclizing the two addition products with ammonium acetate, and coordinating with boron trifluoride diethyl etherate to obtain NHM; carrying out substitution reaction on the NHM and sodium nitrite to obtain NOO; and oxidizing NOO by m-chloroperoxybenzoic acid to obtain NNOO. The reagent can target a tumor hypoxia microenvironment, hypoxia monitoring is achieved, NO is released through photostimulation for tumor gas therapy, meanwhile, the secondary amplification photo-thermal therapy effect is achieved, preparation is controllable, diagnosis and treatment are integrated, and the reagent is sensitive, safe and suitable for biomedical research and clinical diagnosis.

The invention relates to the technical field of biological detection, in particular to a composition for protein precipitation, a protein precipitation agent containing the composition, a protein precipitation combined product, a detection kit and a preparation method and a detection method of a blood analysis sample. The composition for protein precipitation comprises zinc sulfate and ammonium acetate in a dosage ratio of (5-17) mg: (0.5-1) mmol. Compared with the prior art, the composition has the following beneficial effects that the zinc sulfate and the ammonium acetate are matched according to a specific proportion, so that the specific composition is formed, and hemoglobin in a blood sample can be effectively removed by taking the composition as a protein precipitation component.

The invention discloses a method for simultaneously determining N-sodium laureth sarcosinate and phenol red residues in an injection based on a UPLC-MS / MS (Ultra Performance Liquid Chromatography-Mass Spectrometry / Mass Spectrometry) method. According to the method, on the basis of an ultra-high performance liquid chromatography-tandem triple quadrupole mass spectrometer, a 5mM ammonium acetate solution (containing 10% acetonitrile) is taken as a phase A, a 0.2% acetic acid acetonitrile solution is taken as a phase B, a Waters Acquity UPLCBEH C18 column is selected, ESI is taken as a mass spectrometry detection ion source, and the two process residues in the injection are accurately quantified at the same time in a negative ion scanning and multi-reaction monitoring mode. The method is simple in pretreatment, high in detection sensitivity and good in reproducibility, and can be used for corresponding injection process residue identification and quality control.

The application discloses a detection method and application of a fingerprint spectrum and a mark characteristic effective component of compound tung oil for burns and a detection method of the fingerprint spectrum, and the detection method of the fingerprint spectrum comprises the following steps: preparing a sample solution and a standard control solution of the compound tung oil for burns, and adopting HPLC chromatography to construct the fingerprint spectrum of the compound tung oil for burns; the HPLC chromatography conditions for constructing the fingerprint spectrum of the compound tung oil for burns comprise the following steps: adopting an octadecyl silica water-resistant analysis column chromatographic column, adopting methanol (A) and 0.08-0.12% ammonium acetate (B) as a mobile phase, adopting a flow rate of 0.5-0.7 mL / min, and adopting a sample injection amount of 5-15 muL. The method system is reliable in results and provides a scientific screening method for quality control of the compound tung oil for burns.

The invention belongs to the technical field of glycine preparation, and particularly discloses a preparation method of glycine. The method comprises the following steps: controlling the reaction temperature, efficiently synthesizing ammonium chloroacetate from chloroacetic acid and liquid ammonia in a reactor, carrying out catalytic ammonolysis on the ammonium chloroacetate and ammonia gas in a reactor filled with a solid catalyst to realize continuity and reinforcement of the process, and carrying out alcohol precipitation crystallization, separation and purification to obtain glycine. The solid catalyst provided by the invention has the advantages of simple preparation, reproducibility, long service life, no metal pollution, easily available raw materials, controllable cost, long-acting cyclic utilization, high efficiency, simple recovery and the like; the method for preparing glycine by using the solid catalyst solves the problems of high consumption, high recovery cost, low production and purification efficiency and pollution caused by the traditional catalyst, and is a key technology for green and low-cost industrial production of glycine.

The invention discloses a novel metal-free iodine-based binary catalyst system, belongs to the technical field of organic catalysis and high polymer materials, and is characterized in that an iodine-based charge transfer compound composed of I2, tetrabutylammonium acetate (TBAAc) and other quaternary ammonium salts catalyzes and oxidizes heterobutane and cyclic anhydride for controlled alternate ring opening copolymerization. In addition, the method has been effectively applied to ring-opening copolymerization by combining an epoxide and a cyclic anhydride. The catalyst system in the preparation method disclosed by the invention has the advantages of low cost, easiness in obtaining, low potential toxicity and biodegradability, and has a great practical application value.

The invention discloses an in-situ leaching liquid injection system and method for high-altitude ionic rare earth ore, and belongs to the field of rare earth hydrometallurgy. The system is composed of a liquid injection well pattern, a layered liquid injection device, a first liquid supply system, a second liquid supply system and a collection system. Exploring the thickness of an ore body weathering crust and vertical distribution of rare earth / impurities; the liquid injection hole is vertically divided into an upper layer liquid injection area (1 / 3-1 / 2 of the upper part) and a lower layer liquid injection area (1 / 2-2 / 3 of the lower part); a 1.0-1.4 wt% low-concentration diethylenetriamine-ammonium acetate composite leaching agent is injected into the upper layer, and co-leaching of impurities such as aluminum and iron is reduced; 1.5-2.5 wt% of high-concentration diethylenetriamine-ammonium acetate composite leaching agent is injected into the lower layer to ensure efficient leaching of rare earth; and rare earth-rich leaching liquid is collected. Compared with a traditional full-layer high-concentration process, the method has the advantages that the use amount of a leaching agent is reduced by 20-40% while the rare earth leaching rate is kept to be larger than or equal to 90%, the aluminum ion concentration of the leachate is reduced by 30-60%, the agent cost and the follow-up impurity removal load are remarkably reduced, and the method is particularly suitable for the high-altitude, low-temperature, low-air-pressure and thick-weathered crust environment.

The invention relates to the technical field of catalyst preparation, in particular to a coal-fired catalyst and a preparation method and application thereof.The coal-fired catalyst is at least prepared from, by weight, 180-300 parts of organic salt solution, 200-350 parts of inorganic salt solution and 50-70 parts of water, the organic salt solution at least comprises pyridinium acetate or sodium benzoate, and the inorganic salt solution at least comprises ammonium acetate or sodium benzoate; the problems that an existing oxygen supply combustion-supporting additive is poor in using effect, coal cannot be fully combusted, and the combustion efficiency cannot be remarkably improved are solved, and the application requirement of the subsequent fire coal field is better met.

FIELD: pharmacology.SUBSTANCE invention can be used to determine the concentration of an anti-tuberculosis drug in blood serum. The method for determining the concentration of bedaquiline in the blood serum in patients with tuberculosis or mycobacteriosis is that whole blood samples are centrifuged at 3000 rpm for 20 minutes, then the blood plasma is collected in sterile 1.5 mL Eppendorf tubes, then 900 mcL of acetonitrile are added to 300 mcL of plasma and centrifuged at 13500g for 15 minutes, then 1 mL of the supernatant is transferred to a chromatographic vial and make the assay by UHPLC MS / MS using an Athena UHPLC C18, 1.8 mcM, 120A, 2.1×100 mm chromatography column, when using an aqueous solution containing 5 g / L of ammonium acetate, 25 ml / L of concentrated acetic acid, 2 ml / L trifluoroacetic acid as mobile phase A and 100% acetonitrile as mobile phase B, the concentration of bedaquiline is determined using a pre-plotted calibration curve.EFFECT: determination of bedaquiline in human blood plasma in a time not exceeding 6 minutes.1 cl, 9 dwg, 6 tbl

The invention discloses a method for detecting 5 '(E)-VPA phosphoramidite monomer related substances, and belongs to the technical field of liquid chromatography detection. Related substances comprise 5 '-(E)-VP-2'-OMe-A (Bz), 5 '(Z)-VPA, 5'-(E)-VP-2 '-OMe-A-CE-P and 5' (E)-VPA-OX, and chromatographic detection conditions comprise that the column temperature is 23-27 DEG C, a stationary phase of a chromatographic column is octadecyl bonded silica gel, a mobile phase A is an ammonium acetate solution, a mobile phase B is acetonitrile, gradient elution is performed, and the like. According to the method, four related substances in the 5 '(E)-VPA phosphoramidite monomer are effectively separated through specific liquid chromatography conditions, the system adaptability, specificity, linearity and range, detection limit, quantitation limit and accuracy verification of the method all meet acceptable standards of pharmacopoeia, and detection of multiple related substances can be completed within a short time; and a reliable means is provided for detecting and controlling the quality of the 5 '(E)-VPA phosphoramidite monomer.

The invention discloses a method for detecting related substances of a fumaric acid Vonoprasone intermediate product by applying a high performance liquid chromatography, and the chromatographic conditions are as follows: a chromatographic column filler uses high-purity porous spherical silica gel particles coated with charged nano polymer microspheres, an ammonium acetate-acetonitrile system is used as a mobile phase, an ultraviolet detector is used as a detector, and the chromatographic column filler is used for detecting the related substances of the fumaric acid Vonoprasone intermediate product. According to the method, the detection of intermediate products 1 related substances, namely 4-dimethylaminopyridine and pyridine-3-sulfonic acid, generated in the production process of the Vonorazan fumarate is accurately realized, and a simple and reliable method is provided for the detection of the intermediate products generated in the production process of the Vonorazan fumarate.

This invention relates to the field of high-purity material analysis technology, and discloses a method for simultaneously separating and enriching copper, cadmium, nickel, cobalt, zinc, lead, and barium in lithium carbonate. The steps are as follows: dissolving a lithium carbonate sample in nitric acid to obtain an acidified sample solution; adjusting the acidified sample solution to an alkaline pH range of 9.5-10.5 using an ammonia-ammonium acetate alkaline buffer solution; passing the alkaline solution through a solid-phase extraction column filled with iminodiacetic acid-type chelating resin, where copper, cadmium, nickel, cobalt, zinc, lead, and barium ions are selectively adsorbed onto the resin; and eluting the adsorbed heavy metal ions with acid to achieve separation and enrichment. This invention effectively overcomes the inhibition and interference of the lithium carbonate matrix on the detection of trace heavy metals, and in particular significantly improves the adsorption and recovery rate of elements such as barium. It achieves efficient separation and enrichment of multiple heavy metals in complex matrices, providing a reliable pretreatment solution for high-sensitivity and high-accuracy quality control analysis of lithium carbonate products.

The application discloses a kind of belongs to analytical detection technical field, specifically related to a kind of determination method of etomidate content in electronic cigarette oil, comprising the following steps: using step-by-step dilution method to pretreat the electronic cigarette oil to be measured to obtain test sample;Using high performance liquid chromatography tandem mass spectrometry technique to determine the content of etomidate in the test sample;The chromatographic conditions in the high performance liquid chromatography tandem mass spectrometry technique include: chromatographic column: n-octadecyl column;Mobile phase A phase: 4mmol / L-6mmol / L ammonium acetate+0.05% (v / v)-0.15% (v / v) formic acid aqueous solution;Mobile phase B phase: methanol.The determination method of etomidate content in the electronic cigarette oil can not only greatly save the solvent usage amount, but also can ensure the accuracy of detection, reduce the influence of matrix effect.

The invention belongs to the field of chemical analysis and testing, and particularly relates to a fluorescent probe for preparing a reagent for detecting elastase as well as a synthesis method and application of the fluorescent probe. The preparation method comprises the following steps: dissolving 2-dicyanomethylene-3-cyano-4, 5, 5-trimethyl-2, 5-dihydrofuran and 6-aminopyridine-3-formaldehyde in ethanol, and heating and refluxing a reaction solution at 50 DEG C under the acidic condition of ammonium acetate to obtain an intermediate TCF-N-NH2; and dissolving the intermediate TCF-N-NH2 and pentafluoropropionic anhydride in dichloromethane, stirring the reaction solution at the temperature of 0 DEG C to room temperature under the alkaline condition of pyridine, and separating and purifying the obtained crude product through thin layer chromatography to obtain the final orange product TCF-NF. The fluorescent probe obtained by the invention can quickly recognize elastase in deionized water.

The invention discloses a small molecular probe based on an imidazo [1, 5-a] pyridine skeleton, a preparation method and application, and belongs to the field of activatable small molecular fluorescent probes. The preparation method of the small molecular probe based on the imidazo [1, 5-a] pyridine skeleton comprises the following steps: dissolving 2-benzoylpyridine and ammonium acetate in acetic acid, adding salicylaldehyde, heating and stirring to generate a compound 3; and dissolving the compound 3 in dichloromethane, adding pyridine, stirring, adding 4-bromobutyryl chloride, and continuously stirring to obtain a compound 1, namely the small molecule probe. The small molecule probe can be used for detecting hydrazine in a biological system or drinking water.

The invention discloses a method for determining barium sulfate in fluorite mine. The method comprises hydrochloric acid, nitric acid, hydrofluoric acid, sulfuric acid-hydrochloric acid mixed acid, ammonium acetate and sulfuric acid. The determination method of barium sulfate in fluorite mine comprises the following steps: S1, reagent proportioning; s2, selecting an instrument; s3, preparing a sample; s4, step analysis; s5, calculating a result; and S6, matters needing attention. The invention belongs to the technical field of mineral composition analysis, and particularly relates to a method for measuring barium sulfate in fluorite mine, which comprises the following steps: firstly, treating a sample with hydrochloric acid, nitric acid and hydrofluoric acid, evaporating to be nearly dry, dissolving soluble salts with a hydrochloric acid-sulfuric acid mixed solution, then filtering, burning filter residues, and finally weighing to obtain the weight of barium sulfate. The method is simplified and optimized on the basis of a national standard method, the method is convenient and fast to operate, the time is greatly shortened, and the result is stable. The method is suitable for the fields of mine production, laboratory rapid detection and the like.

The invention discloses an imidazolyl BODIPY derivative viscosity fluorescent probe with an aggregation-induced fluorescence enhancement (AIEE) effect and application thereof, the imidazolyl BODIPY derivative viscosity fluorescent probe is realized by the following method: taking a 2-formaldehyde BODIPY derivative (I), diphenyl ethanedione and aniline as raw materials, and carrying out Debus-Radziszewski imidazole synthesis reaction under the catalytic action of ammonium acetate, and the chemical structural formula of the imidazolyl BODIPY derivative viscosity fluorescent probe is as shown in formula (II). The preparation method is simple in reaction step, mild in reaction condition, simple and convenient to separate and purify and high in yield; the fluorescent probe has an aggregation-induced fluorescence enhancement effect, has high responsiveness to viscosity, can be used for detecting viscosity change in a solution and cells, and can provide an effective detection method for researching physiological action of viscosity in cells.