33 results about "Benzoic hydrazide" patented technology

The invention discloses self-adhesion-crosslinking double modified bamboo powder, a preparation method and application, and relates to the technical field of composites.The preparation method of the modified bamboo powder comprises the following steps that S1, bamboo powder, 2, 5-dihydroxyterephthalic acid, 4-aminobenzoyl hydrazine, N, N '-diisopropylcarbodiimide and tris (hydroxymethyl) aminomethane are mixed for a reaction; and S2, trimesic acid is added into the solution obtained after the reaction in the S1 for a reaction, filtering, washing and drying are conducted, and the self-adhesion-crosslinking double modified bamboo powder is obtained. The prepared modified bamboo powder is green and environmentally friendly, through a self-adhesion mechanism, a cross-linking mechanism, a branched-chain phenyl heterogeneous nucleation mechanism and the like, the interfacial compatibility of PBAT and the bamboo powder and the crystallinity of PBAT are improved, and therefore the mechanical property of PBAT / bamboo powder is enhanced.

The invention discloses an organic phosphorescent material intermediate for an OLED (Organic Light Emitting Diode) as well as a preparation method and application of the organic phosphorescent material intermediate, and relates to the field of organic phosphorescent materials. The intermediate is prepared through a Diels-Alder cycloaddition reaction between trans-cyclooctene and 3, 6-diphenyltetrazine, the reaction is carried out under the conditions that the temperature is 20-30 DEG C and the time is 10-30 minutes, and the mass ratio of the trans-cyclooctene to the 3, 6-diphenyltetrazine is 1: (1.0-2.5). Trans-cyclooctene is prepared by isomerizing cis-cyclooctene under the irradiation of 254nm ultraviolet light in the presence of a photosensitizer; the 2, 3, 6-diphenyl tetrazine is prepared by condensation, cyclization and purification of benzaldehyde and benzoyl hydrazine. The purity of the prepared intermediate reaches up to 99.2%, the yield reaches 82.4%, the intermediate serving as an OLED luminescent material has excellent thermal stability, and the quantum efficiency is still kept at 90.1% after HTHH treatment is conducted for 1000 h. The invention provides a new intermediate choice for developing a high-performance OLED (Organic Light Emitting Diode) material.

The present invention relates to a class of (R)-2-aryl-4,5-dihydrothiazole-4-carboxylic acid derivatives containing dihydrazide having fungicidal activity as shown in general formula (I), as well as preparation methods and applications thereof. A pesticide molecule design method of splicing active fragments is used to connect differently substituted (R)-2-aryl-4,5-dihydrothiazole-4-carboxylic acids with differently substituted benzoylhydrazides, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R 10 As defined in the specification. The technical effect of the present invention is: a class of (R)-2-aryl-4,5-dihydrothiazole-4-carboxylic acid derivatives containing dihydrazide with broad-spectrum fungicidal activity has been discovered, which is a fungicide with broad application prospects.

The present application relates to the technical field of forestry pest control, and discloses a pentacyclic triterpene derivative, a preparation method thereof and application of the pentacyclic triterpene derivative in pine wood nematode control. The pentacyclic triterpene derivative has a structure as shown in formula I and is prepared by the following steps: tea saponin is dissolved in ethanol, adsorbed by activated carbon, concentrated, adsorbed by macroporous resin, eluted, desorbed, hydrolyzed, crystallized, purified to obtain a pentacyclic triterpene compound, the hydroxyl group on the pentacyclic triterpene compound is protected to obtain an intermediate I, the double bond on the intermediate I is protected to obtain an intermediate II, 4-chlorobenzoyl hydrazine is added and reacted with the intermediate II to obtain an intermediate III, the double bond of the intermediate III is deprotected to obtain an intermediate IV, and the hydroxyl group of the intermediate IV is deprotected to finally obtain the pentacyclic triterpene derivative. The pentacyclic triterpene derivative has the effect of preventing and treating pine wood nematode disease and can be prepared into a pine wood nematode-killing pharmaceutical preparation.

The invention belongs to the technical field of preparation of oxadiazole derivatives. The invention provides a method for preparing a 2-amino-1, 3, 4-oxadiazole derivative through electro-catalysis, which comprises the following steps: adding 0.2 mmol of benzoyl hydrazine compound, 0.4 mmol of tetrabutylammonium iodide, 0.4 mmol of 1, 4-diazabicyclo [2.2. 2] octane, 0.4 mmol of sodium bicarbonate and 6 mL of acetonitrile into an electrolytic tank; then, 0.3 mmol of a phenyl isothiocyanate compound is added dropwise; the reaction is carried out under a direct-current constant current between the electrode anode and the electrode cathode. According to the method, benzoyl hydrazine and phenyl isothiocyanate are taken as reaction substrates through electro-catalysis, reagents such as acetonitrile which is low in price and low in toxicity are taken as solvents, an oxidizing agent in a conventional reaction is replaced by a mode of introducing current, and the oxadiazole compound is synthesized under mild and green conditions.

This application relates to a MALDI reactive matrix, 5-methoxy-2-hydroxybenzoyl hydrazine, for the analysis of reducing sugars, belonging to the field of sugar biochemical analysis technology. This application provides the application of 5-methoxy-2-hydroxybenzoyl hydrazine as a MALDI reactive matrix in combination with 2,5-dihydroxybenzoic acid in the analysis of reducing sugars. Specifically, 5-methoxy-2-hydroxybenzoyl hydrazine is the reactive matrix, possessing a hydrazine reactive group that can react with the hemiacetal terminus of reducing sugars. 2,5-dihydroxybenzoic acid acts as a catalyst, significantly promoting the efficient reaction between 5-methoxy-2-hydroxybenzoyl hydrazine and reducing sugars. The 5-methoxy-2-hydroxybenzoyl hydrazine / 2,5-dihydroxybenzoic acid composite matrix provided in this application can form a uniform co-crystallization with reducing sugars, exhibiting good signal reproducibility (RSD < 10%) and good linearity in the range of 0.2~20 pmol / μL (R0). 2 > 0.999).

The present invention belongs to the technical field of preparation of oxadiazole derivatives. The present invention provides a method for preparing 2-amino-1,3,4-oxadiazole derivatives by electrocatalysis, comprising the following steps: adding 0.2mmol of benzoylhydrazide compounds, 0.4mmol of tetrabutylammonium iodide, 0.4mmol of 1,4-diazabicyclo[2.2.2]octane, 0.4mmol of sodium bicarbonate, and 6mL of acetonitrile to an electrolytic cell; then adding 0.3mmol of phenyl isothiocyanate compounds dropwise; reacting under a DC constant current between an electrode anode and an electrode cathode. The present invention adopts electrocatalysis with benzoylhydrazide and phenyl isothiocyanate as reaction substrates, acetonitrile and other cheap and less toxic reagents as solvents, and passing current to replace the oxidant in conventional reactions, thereby synthesizing oxadiazole compounds under mild and green conditions.

The invention provides an anti-neuroinflammation medicine as well as a preparation method and application thereof. The anti-neuroinflammation medicine comprises an active component and lipidosome, the active component is an inhibitor 4-aminobenzoyl hydrazine of myeloperoxidase; the liposome is prepared from phospholipid, cholesterol and distearoyl phosphatidyl ethanolamine-thioketal-polyethylene glycol; the method comprises the following steps: weighing lipidosome and 4-aminobenzoyl hydrazine, dissolving, and carrying out rotary evaporation to obtain a lipid membrane; adding a phosphate buffer solution into the lipid membrane, stirring in a water bath, performing ultrasonic treatment, filtering, centrifuging and purifying to obtain the medicine, according to the active oxygen response-based liposome delivery system disclosed by the invention, 4-aminobenzoyl hydrazine is encapsulated in liposome to form a drug, and after the drug enters a brain inflammation microenvironment area of the Alzheimer's disease, the active oxygen can break a thioketal bond, so that local release of 4-aminobenzoyl hydrazine is triggered, targeted inhibition of myeloperoxidase is realized, and the drug delivery effect is improved. The oxidative stress level is reduced, the neuroinflammation is relieved, and the cognitive impairment is effectively improved.

The invention relates to a separation and purification method and application of an azastine hydrochloride benzoyl hydrazone intermediate, and the separation and purification method comprises the following steps: mixing methylhexahydroazepine-4-one hydrochloride, sodium bicarbonate and benzoyl hydrazine, reacting, carrying out post-treatment, and recrystallizing to obtain the azastine hydrochloride benzoyl hydrazone intermediate. According to the method, a benzoyl hydrazone intermediate separation and purification process is provided, quality control points are increased, and the quality risk of a final product is reduced.

The invention discloses a synthesis method of 4-(3-hydrazide oxopropyl) benzoyl hydrazine, and belongs to the field of organic synthesis. According to the invention, 4-(3-ester oxopropyl) methyl benzoate is used as a raw material, and is subjected to a hydrazide reaction with hydrazine hydrate in a reaction solvent to obtain the product 4-(3-hydrazide oxopropyl) benzoyl hydrazine. And under optimal reaction conditions, after the reaction liquid is recycled for multiple times, the comprehensive yield can reach 87%, and the product purity is relatively high.

The present invention provides a class of benzoyl hydrazide compounds, belonging to the technical field of pharmaceutical chemistry. The structure of the benzoyl hydrazide compounds is shown in general formula I. The benzoyl hydrazide compounds of the present invention have the effect of killing Schistosoma japonicum. The emergence of new drugs overcomes the problem of drug resistance caused by long-term use of existing anti-schistosomiasis drugs, and has important scientific value and research value for finding new anti-schistosomiasis drugs.

The invention discloses a polyaspartic acid derivative based on hydroxybenzoyl hydrazine modification and a preparation method and application thereof.The hydroxybenzoyl hydrazine is introduced into a peptide chain of polyaspartic acid through a graft copolymerization method, three derivatives are synthesized, the derivatives can be combined with metal ions such as Ca < 2 + > to generate water-soluble complexes, and the water-soluble complexes can be used for preparing the polyaspartic acid derivative based on hydroxybenzoyl hydrazine modification and the preparation method and application of the polyaspartic acid derivative based on hydroxybenzoyl hydrazine modification. The scale inhibitor has good scale inhibition and antibacterial properties, and also has a certain corrosion inhibition effect. In addition, the derivative has a good inhibition effect on escherichia coli, and the escherichia coli is a main pollution source in circulating cooling water. The derivative also has better optical properties, and is convenient to cooperate with a fluorescence monitor in industrial production to monitor the concentration of the derivative in a circulating cooling water pipeline in real time, so that the industrial production process is optimized. Therefore, the scale inhibition performance, the corrosion inhibition performance and the antibacterial performance of the polyaspartic acid derivative are remarkably improved by modifying the polyaspartic acid derivative through the hydroxybenzoyl hydrazine, meanwhile, application of phosphorus-containing compounds is avoided, and the negative influence on the environment is effectively relieved.

The invention relates to the technical field of degradable materials, in particular to a degradable polyester resin material and a preparation method thereof. The polyester resin material is mainly prepared from PBAT, PBS, a chitosan stearoyl graft, a chitosan stearoyl catechol double graft, sebacyl dibenzoyl hydrazine, a chain extender containing an epoxy functional group, anhydrous zinc acetate and an antioxidant according to a specific proportion, and a multi-stage reaction extrusion and special heat treatment process is adopted. Through grafting and introduction of a reversible coordination network, the thermal deformation temperature of the polyester material is greatly improved, a heat-sealing window is remarkably widened, and collaborative optimization of mechanical properties and degradation properties is realized. The obtained resin material has excellent film-forming property, thermal and mechanical properties and environmental friendliness, and is suitable for the fields of green packaging and the like.

The invention relates to a novel compound as well as a preparation method and an application thereof, in particular to an N '-aryl-4-[5-(trifluoromethyl)-1, 2, 4-oxadiazole-3-yl] benzoyl hydrazine compound as well as a preparation method and an application of the N'-aryl-4-[5-(trifluoromethyl)-1, 2, 4-oxadiazole-3-yl] benzoyl hydrazine compound. The structural formula of the N '-aryl-4-[5-(trifluoromethyl)-1, 2, 4-oxadiazole-3-yl] benzoyl hydrazine compound is as shown in a formula I: # imgabs0 #, and the structural formula of the N'-aryl-4-[5-(trifluoromethyl)-1, 2, 4-oxadiazole-3-yl] benzoyl hydrazine compound is as shown in a formula II, wherein R is selected from hydrogen, methyl, naphthyl, chlorine, bromine, trifluoromethyl, 2, 4-dichloro and 2-fluoro-4-chlorine. The compound disclosed by the invention particularly shows relatively good antifungal activity on botryosphaeria dothidea, pythium aphanidermatum and soybean rust, more choices can be provided for research and development of antifungal drugs, and the compound disclosed by the invention has a wide application prospect.

The invention discloses a vanillin-based flame retardant as well as a preparation method and application thereof, and belongs to the technical field of flame retardance. In the preparation process of the vanillin-based flame retardant, due to the fact that biomass raw material vanillin is selected to react with hexachlorocyclotriphosphazene containing nitrogen and phosphorus, nitrogen and phosphorus elements are introduced, PLA can be rapidly dehydrated and carbonized, oxygen and heat can be isolated, release of combustible gas and toxic smoke can be effectively reduced, and the flame retardant has the advantages of being high in flame retardant property, good in flame retardant property and the like. The flame retardant property of the PLA is improved. Meanwhile, benzoyl hydrazine is introduced, so that the flame retardant and the PLA can form an intermolecular force, and the mechanical property of the PLA is improved. In addition, dipole-dipole interaction is generated between imino groups in the flame retardant and carbonyl groups in PLA molecules, so that the crystallinity of PLA is improved.

The application provides an A,A'-dihydroxynaphthaldehyde hydrazone functionalized conjugated pillar[5]arene and a synthesis method thereof. First, a di-m-benzoic acid methyl ester functionalized conjugated pillar[5]arene and hydrazine hydrate are used as substrates to react in anhydrous ethanol solvent to obtain a di-m-benzoic acid hydrazine functionalized conjugated pillar[5]arene; then the di-m-benzoic acid hydrazine functionalized conjugated pillar[5]arene and 2-hydroxy-1-naphthaldehyde are used as substrates to react in anhydrous methanol to obtain the A,A'-dihydroxynaphthaldehyde hydrazone functionalized conjugated pillar[5]arene HGP5. The sensor molecule HGP5 in the application can detect Arg in a "colorimetric fluorescence" dual-channel mode, and can also detect Al 3+ in a super-sensitive mode under fluorescence. In addition, the chemical sensor has potential application in cell imaging, and can detect Al 3+ and Arg in cells. The application provides a new idea for developing a novel supramolecular fluorescent material for detecting Arg and Al 3+ in an aqueous solution.

The invention discloses 3-(1-(2, 4-dichlorobenzyl)-1H-indazole-3-yl) benzoyl hydrazine with a chemical formula of C21H16Cl2N4O, and also discloses a preparation method of the 3-(1-(2, 4-dichlorobenzyl)-1H-indazole-3-yl) benzoyl hydrazine and an application of the 3-(1-(2, 4-dichlorobenzyl)-1H-indazole-3-yl) benzoyl hydrazine in synthesis of male contraceptive drugs. The 3-(1-(2, 4-dichlorobenzyl)-1H-indazole-3-yl) benzoyl hydrazine compound disclosed by the invention can cause the reduction of sperm concentration of male SD (Sprague Dawley) rats and ICR (Induced Cyclic Resonance) mice and the disorder of arrangement of testicular spermatogenic cells, and has a spermatogenic inhibition effect.

The invention provides a preparation method of an isoxazole-oxadiazole compound, which comprises the following steps: reacting 4-chloro-2-fluoro-3-vinylbenzoic acid with tert-butyloxycarboryl hydrazine in the presence of a condensing agent and a catalyst, then removing a protecting group under an acidic condition to obtain an intermediate 4-chloro-2-fluoro-3-vinylbenzoyl hydrazine, and then reacting with N, N-dimethylformamide to obtain the isoxazole-oxadiazole compound. The method comprises the following steps: cyclizing N, N '-carbonyldiimidazole in the presence of alkali, carrying out an O-alkylation reaction with an alkylation reagent R1-X in the presence of alkali, and carrying out an olefin dihydroxylation-sodium periodate oxidation cleavage reaction in the presence of an oxidant and a catalyst; reacting with hydroxylamine in the presence of alkali, and finally carrying out 1, 3-dipolar cycloaddition reaction with an acrylate compound in the presence of alkali and an oxidizing agent. The method is carried out at room temperature, has the advantages of mild conditions, simplicity in operation and the like, is wider in application range compared with a traditional synthesis method, and has important synthesis application value.

The application discloses a polyaspartic acid derivative modified by hydroxybenzoyl hydrazine, a preparation method and application thereof, and adopts a graft copolymerization method to introduce the hydroxybenzoyl hydrazine into a peptide chain of polyaspartic acid, and synthesizes three derivatives. 2+ The derivatives can be combined with Ca 2+ Metal ions to generate water-soluble complexes, have good scale inhibition and bacteriostatic performance, and have certain corrosion inhibition effect. In addition, the derivatives have good inhibition effect on escherichia coli, which is the main pollution source in circulating cooling water. The derivatives also have good optical properties, which are convenient for real-time monitoring of the concentration of the derivatives in the circulating cooling water pipeline in cooperation with a fluorescence monitor in industrial production, and optimization of the industrial production process. Therefore, the polyaspartic acid derivative modified by the hydroxybenzoyl hydrazine significantly improves the scale inhibition, corrosion inhibition and bacteriostatic performance, avoids application of a phosphorus-containing compound, and effectively reduces negative influence on the environment.

The invention belongs to the field of medicines, and particularly relates to a novel benzoyl hydrazine antitumor compound as well as a preparation method and application thereof. The benzoyl hydrazine compound with a novel structure is prepared by adopting a simple and efficient synthesis method, and the specific structural general formula of the benzoyl hydrazine compound is as follows: imgabs0 #. The research on the in-vitro anti-tumor activity of the compound shows that the novel benzoyl hydrazine compound has an obvious inhibition effect on the growth of human hepatoma cells (HepG-2), human gastric cancer cells (SGC-7901) and human breast cancer cells (MDA-MB-231); therefore, the benzoyl hydrazine compound can be used as a lead compound or a candidate compound for the development of antitumor drugs.

The invention provides an aluminum ion complex for detecting trace water, a preparation method of the aluminum ion complex and application of a fluorescence sensor, and belongs to the technical field of fluorescence sensors. According to the invention, pyridine-2-formaldehyde and benzoyl hydrazine are subjected to a one-step reaction to synthesize a ligand, the ligand is complexed with aluminum ions to prepare the aluminum ion complex capable of detecting trace water, the preparation method is simple, the raw materials are low in price, and the complex is good in stability. The complex can be used as a fluorescence sensor to show better responsiveness and higher sensitivity to water, the detection process is simple and rapid, and visual qualitative detection can be performed on water; the moisture in the food can be quantitatively detected by utilizing a good linear relationship between the fluorescence emission intensity and the water content. Therefore, the complex prepared by the invention has potential application prospects in the aspect of quantitative analysis of water.

The application discloses a copper-loaded nano self-assembly and a preparation method and application thereof, and the copper-loaded nano self-assembly is formed by self-assembly of a compound N'-linolenoyl-N-methyl thiobenzoyl hydrazine or a pharmaceutically acceptable salt thereof after coordination with copper ions. The N'-linolenoyl-N-methyl thiobenzoyl hydrazine is prepared by acylation reaction of linolenoyl chloride and N-methyl thiobenzoyl hydrazine, and then the N'-linolenoyl-N-methyl thiobenzoyl hydrazine is co-dissolved with DSPE-PEG in an organic solvent and injected into a copper-containing aqueous phase to form nanoparticles by self-assembly. The obtained copper-loaded nano self-assembly has uniform particle size (about 108 nm), is spherical, has good stability, has a significant killing effect on MC38 cells in vitro, can effectively inhibit the growth of a subcutaneous tumor of a mouse in vivo and has good safety. The application overcomes the problems of low solubility and poor copper ion delivery efficiency of existing copper ion carriers, and provides a novel nano delivery platform for copper death-mediated tumor treatment.

The invention discloses thiazole-2-yl benzoyl hydrazine derivatives as well as a preparation method and application thereof, and belongs to the field of medicinal chemistry. The thiazole-2-yl benzoyl hydrazine derivative shows an excellent broad-spectrum plant pathogenic bacterium resisting effect, has the advantage of being simple in synthesis method, and has important significance on discovery of novel bactericides and overcoming of drug resistance of plant pathogenic fungi.

The invention discloses a 2-(difluoromethyl)-1, 3, 4-oxadiazole derivative as well as a synthesis method and application thereof, and the 2-(difluoromethyl)-1, 3, 4-oxadiazole derivative is obtained by cyclizing benzoyl hydrazine by using economical and efficient (trifluoromethyl) trimethylsilane (TMSCF3) as a bifunctional C1 synthesis source and a difluoromethylation reagent and elemental sulfur as a sustainable sulfur source. The method is mild in reaction condition, does not contain precious metal and harmful byproducts, shows wide compatibility with various functional groups and substrates, and can be used for efficiently preparing derivatives with complex structures at medium to high yield. The strategy of the 1, 2, 4-oxadiazole derivative can provide a modular path for oriented synthesis of fluorine-containing heterocyclic molecules with highly functionalized structures or complex structures.

The invention belongs to the technical field of biological inorganic chemistry, and particularly relates to an imidazolyl Schiff base acylhydrazone ligand, a preparation method of the imidazolyl Schiff base acylhydrazone ligand, an imidazolyl Schiff base acylhydrazone metal drug and application. The invention provides a brand new imidazolyl Schiff base acylhydrazone ligand, the imidazolyl Schiff base acylhydrazone ligand is N '-(5-bromo-2-hydroxybenzylidene)-4-(1-imidazole) benzoyl hydrazine, then the imidazolyl Schiff base acylhydrazone ligand is coordinated with zinc nitrate or europium nitrate, and the imidazolyl Schiff base acylhydrazone metal drug is obtained. A new ligand is obtained by adopting the method disclosed by the invention, a new drug with a clear structure, low toxicity and anticancer activity is prepared by adopting the ligand, and the technical defects of metal drugs and Schiff base drugs in the prior art are overcome.

The invention discloses application of a pyrimidyl hydrazide compound in detection of copper ions or mercury ions and a method for detecting the copper ions or the mercury ions. The pyrimidinyl hydrazide compound has a structural formula shown in the specification. The pyrimidinyl hydrazide compound N '-(2-pyrimidinyl) benzoyl hydrazine prepared by the invention is a dual-optical probe and can be used for detecting low-concentration bivalent copper ions or bivalent mercury ions in a water body.

The invention relates to the technical field of passivators, and discloses a preparation method of a novel passivator, 4-chloromethyl benzoyl hydrazine is prepared from methyl 4-chloromethyl benzoate and hydrazine hydrate, 4-bromomethyl benzoyl hydrazine is prepared through a bromination reaction, and 4-bromomethyl benzoyl hydrazine and acrylamide are subjected to a bromination reaction in cuprous bromide and 2, 2, 6-trimethyl-1, 3-pentanediol monoisobutyrate to prepare the novel passivator. Generating polyacrylamide grafted benzoyl hydrazine under the action of 2, 2 '-dipyridyl; the dialdehyde nano-cellulose is prepared according to the bamboo pulp board raw material, and finally the polyacrylamide grafted benzoyl hydrazine and the dialdehyde nano-cellulose are cross-linked to obtain the passivator with excellent corrosion resistance. According to the novel passivator prepared in the invention, the corrosion resistance can be improved, and the adsorption capacity and the heavy metal ion fixing capacity of the novel passivator are enhanced.

The present invention provides an improved process for the preparation of indometacin of formula (I) by precipitation, crystallization, recrystallization or reslurrying of the intermediate 4-chloro-n-(4-methoxyphenyl) benzohydrazide in a mixture comprising tetrahydrofuran and a C1-C4 linear or branched alkyl alcohol, # imgabs0 #

The application discloses a kind of super-sensitive aluminum ion detection fluorescent probe preparation and application, it is related to converter station valve internal cooling water system aluminum ion fluorescent probe technical field.Probe structure formula is: preparation method is: 4-amino benzhydrazide and 2-hydroxy-1-naphthaldehyde are dissolved in anhydrous ethanol, then reflux, product solution is filtered under vacuum to obtain filtrate, and under the condition of reduced pressure, rotary evaporation dry solvent, obtain benzhydrazide compound based on Schiff base functional group.The application of probe is used to detect the concentration of aluminum ion in sample.The aluminum ion fluorescent probe of the application can be reacted with aluminum ion, and the change of fluorescence spectrum is generated, so that the quantitative detection of aluminum ion is realized.The probe of the application is very sensitive to aluminum ion reaction, so as to facilitate the rapid detection of aluminum ion.The stability of fluorescent probe is good, and then it can be stored for a long time.

The invention relates to a fluorescent molecular probe, a preparation method thereof and application of a complex of the fluorescent molecular probe and zinc ions in glyphosate sensing detection. The invention belongs to the field of fluorescent molecular probes. The method overcomes the defects that glyphosate detection in the prior art is time-consuming, cumbersome, expensive, only qualitative and the like. The fluorescent molecular probe HMB prepared by the invention is a Schiff base type probe taking dicyanoisophorone and benzoyl hydrazine as fluorophores, and the fluorescent molecular probe has the advantages of easily available raw materials and simple operation. The invention further provides a complex HMB-Zn < 2 + > of the fluorescent molecular probe and zinc ions, HMB and HMB-Zn < 2 + > both have a chromogenic sensing function and can show color changes under sunlight and ultraviolet light, and HMB-Zn < 2 + > has a specific recognition function on glyphosate and can be used as a specific indicator for existence of glyphosate in a real water sample and rice roots. And the sensor can also be used for detecting glyphosate in a water body environment and plant tissues.