The invention relates to the technical field of cortex phellodendri chinensis extraction, and provides an extraction process for optimizing
berberine hydrochloride in cortex phellodendri chinensis decoction pieces, the extraction process for optimizing
berberine hydrochloride in the cortex phellodendri chinensis decoction pieces comprises the following steps: taking the cortex phellodendri chinensis decoction pieces, naturally air-
drying, and sieving the crushed
powder to obtain
berberine hydrochloride powder; adding water into dilute sulphuric acid, beta-
glucanase and
cellulase, and mixing for later use; respectively loading the cortex phellodendri chinense
powder in the step 1 and
sulfuric acid into a feeding device, adding into different extraction tanks, and carrying out
reflux extraction; combining all filtrates, concentrating, and adjusting the pH with diluted
hydrochloric acid; and cooling, adding a saturated NaCl solution, preserving overnight at 4 DEG C, carrying out suction
filtration, and
drying. According to the optimized extraction process for
berberine hydrochloride in cortex phellodendri chinensis decoction pieces, the
enzyme activity is improved through dilute sulphuric acid,
plant cell walls are thoroughly damaged by beta-
glucanase and
cellulase, effective components are extracted more sufficiently, and therefore the effects of being capable of accelerating extraction, sufficient in extraction and high in extraction rate are achieved.