136 results about "Calcium concentration" patented technology

An intracellular calcium concentration increase inhibitor containing as the active ingredient (1) a boron compound represented by the formula (I).

The compound represented by the formula (I) inhibits the increase of the intracellular calcium concentration, and therefore it is deemed to be useful as an agent for the prophylaxis and/or treatment of platelet aggregation, ischemic diseases in hearts and brains, immune deficiency diseases, allorgosis, bronchial asthma, hypertension, cerebrovascular spasm, various renal diseases, pancreatitis, Alzheimer's disease, etc.

A crystal constituting a dielectric porcelain, comprised of a first crystal group composed of crystal grains of 0.2 atomic % or less calcium concentration and a second crystal group composed of crystal grains of 0.4 atomic % or more calcium concentration, wherein the ratio of concentration of each of magnesium and a first rare earth element contained in a center portion to that contained in a surface layer portion of crystal grains constituting the first crystal group is greater than the corresponding concentration ratio of crystal grains constituting the second crystal group, and wherein on a polished surface resulting from polishing of the surface of the dielectric porcelain, when the area of crystal grains of the first crystal group is referred to as a and the area of crystal grains of the second crystal group referred to as b, the ratio of b/(a+b) is in the range of 0.5 to 0.8.

A medium for culturing stem cell. The stem cell medium of the invention comprises a fetal bovine serum, one or plurality of amino acid, one or plurality of vitamin, one or plurality of growth factor, one or plurality of inorganic salt, one or plurality of antioxidant, wherein the stem cell medium has a calcium concentration of less than about 1.8 mM, and the fetal bovine serum is present in an amount of less than about 10% by volume of the medium. The stem cell medium of the invention can maintain the proliferative and self-renewal capacity of the stem cells and keep stem cells at a steady stage.

According to a method and device for modulating intracellular calcium concentration in biological tissue, a stimulation probe is applied to the tissue, a non-excitatory stimulation pulse is generated, and the pulse is conveyed to the stimulation probe. In one embodiment concerning cardiac tissue, a stimulation probe is applied to a patient's heart, a signal is received from at least one sensor responsive to the patient's cardiac muscle activity, a non-excitatory stimulation pulse responsive to the signal is generated, and the pulse is conveyed to the stimulation probe.

The invention relates to application of collagen chelate in the preparation of medicament or food for enhancing bone quality. The medicament or food can enhance bone strength, can enhance bone strength and bone density at the same time and can be used for curing and/or preventing osteoporosis. The collagen chelate is a metalloprotein conjugate; compared with calcium carbonate (CaCO3) with the same calcium concentration, the collagen chelate can enhance the bone density by 4.4 percent and enhance the bone strength by 9.9 percent; and compared with a mixture of collagen and calcium carbonate (CaCO3) with the same concentration of collagen and calcium carbonate, the collagen chelate has a more obvious effect.

A method of performing regional citrate anticoagulant dialysis of a patient's blood includes flowing blood from and back to the patient through an extracorporeal circuit including a dialyzer having semi-permeable dialysis membranes and a dialysate chamber surrounding the membranes. The method further includes flowing a dialysate containing calcium and citrate through the dialysate chamber of the dialyzer and introducing citrate into the patient's blood upstream of the dialyzer, whereby the patient's blood is dialyzed. The method can further include predicting the concentration of systemic ionized calcium in the blood of the patient at any point in the dialysis treatment or post-dialysis, such as by a mathematical model. The method can further include statistically correcting the preliminary predicted post-dialysis concentration of systemic ionized calcium in the patient's blood to provide a final predicted post-dialysis systemic ionized calcium concentration. The method can further include statistically correcting the preliminary predicted systemic ionized calcium concentration for any time point during the dialysis treatment to provide a final predicted systemic ionized calcium concentration for that time point.

A Hebbian synapse emulation circuit models the conductance of a synapse circuit. In one embodiment, the circuit includes a counter that provides control signals determining the conduction states of electrical pathways, which define the conductance level of the synapse. The counter can increment, decrement, or leave the same, the synapse conductance value based upon potentiation and depression signals that are derived from a voltage that corresponds to the calcium concentration in the synapse. The counter can be coupled to a plurality of synapse circuits on a time-shared basis.

This invention provides a method for treating sewage containing high concentration of calcium and organic compounds, comprising the following procedures: (1) remove the floating oil of the sewage through the regulating tank and oil separating tank and then send to the anaerobic reactor for treatment; (2)adjust the pH value of the anaerobic outlet water to 6-9, and then add in decalcifying and desferri softening agent for settling separation; (3)send the softened outlet water to the second-stage aeration biological filtration tank to decrease the COD to the required value. This method is characterized of a high organic compound treatment load, a high decalcifying and desferri efficiency and a small need for land area, Besides, it can decrease the CODcr concentration, calcium concentration, iron concentration of the original sewage from 10000-20000mg/L, 500-6000mg/L and 0-500mg/L respectively to below 800mg/L, 200mg/L and 10mg/L, respectively.

The invention is directed to a method of determining a dosage of phosphorus binder for a patient undergoing dialysis treatment to achieve a pre-dialysis serum phosphorus concentration within a desired concentration range while achieving a desired net accumulation of calcium. The method includes determining the dosage of phosphorus binder that will achieve pre-dialysis serum phosphorus concentration of the patient that is within the desired concentration range while accounting for the change in the amount of phosphorus removed by the dialysis treatment when the pre-dialysis serum phosphorus concentration of the patient is within the desired concentration range, determining a dialysate calcium concentration that will result in the desired net accumulation of calcium over a complete dialysis cycle, and dialyzing the patient with a dialysate containing a calcium concentration based upon that determination.

The invention discloses an oral solid lipid nano-particle preparation of calcitonin, which is a particle suspension containing 0.01 percent sodium cholate in a water phase, wherein lipid nano-particles comprise an active medicament component and a lipid material forming the particles. Simultaneously, the preparation method comprises the following steps: dissolving or melting a medicament and a carrier in an organic solvent phase together; quickly infusing the organic phase into the water phase stirred at a low temperature to form a lipid nano-particle dispersion liquid; standing, melting and performing high-speed centrifugal separation on the lipid nano-particle dispersion liquid to obtain a nano-particle deposition; and dispersing the deposition to obtain a target oral calcitonin lipid nano-particle dispersion liquid. The oral solid lipid nano-particle preparation uses the lipid material as a structural matrix material, and the oral solid lipid nano-particle preparation of the calcitonin is prepared through reasonable component proportion to prevent the medicament from leaking in an aqueous medium and release the medicament in modes of in vivo esterase degradation and the like, thus the aim that the medicament contained in a nano-carrier can adjust the serum calcium concentration more reasonably and more safely through biomembranes of mammals is achieved.

A cariostatic food is provided. The food comprises: (1) (i) a phosphorylated saccharide calcium salt; or (ii) a combination of a phosphorylated saccharide salt other than a phosphorylated saccharide calcium salt or a phosphorylated saccharide, and a water-soluble calcium salt other than a phosphorylated saccharide calcium salt; (2) a fluoride; and (3) a polyphenol; wherein the phosphorylated saccharide is composed of a saccharide moiety and phosphate group(s); the content of the component (1) in the food is in an amount suitable to make the calcium concentration in saliva in the oral cavity to be 1 mM to 12 mM when the food exists in the oral cavity; and the content of fluoride in the food is in an amount suitable to make the fluoride concentration in saliva in the oral cavity to be 0.2 ppm to 100 ppm when the food exists in the oral cavity.

Methods for in vivo measurement of lead or other trace elements in bone by x-ray fluorescence (XRF) without independent measurement of underlying tissue thickness are disclosed. In one method, the lead concentration is calculated based on the intensity of a first characteristic fluoresced peak and a function having as an argument the intensity ratio of first and second characteristic fluoresced peaks, with at least one parameter of the function being empirically determined by measurements of calibration phantoms having differing thicknesses of tissue surrogate material. In another method, the lead concentration is measured by estimating tissue thickness based on the intensity of the Compton scattering peak, or ratio of Compton/Rayleigh intensities, and the intensity of a characteristic fluoresced x-ray peak corrected for attenuation by tissue of the estimated thickness. Also disclosed is a method for determining the calcium concentration and density of bone based on XRF spectrum data.

The invention relates to a method for measuring trace calcium in steel. The method is used for measuring the trace calcium in steel by combining a microwave digestion method with an inductive coupling plasma atomic emission spectrograph. The method comprises the following steps: a sample solution which is digested by microwave is cooled and is subjected to constant volume in a measuring flask; standard solutions with different calcium concentrations are prepared and added with acid accordant with the pre-processed sample, and are subjected to constant volume in measuring flasks of the same size; the calcium spectral line intensities in the standard solutions with different calcium concentrations are respectively measured in the inductive coupling plasma atomic emission spectrograph, and a working curve is drawn by taking the element calcium concentrations as the abscissa and taking the spectral line intensities as the ordinate; under the same conditions with the steps, the calcium concentration in the sample solution is measured, and the volume concentration of the calcium element in the sample is calculated according to the working curve. The method has the advantages of simple and fast operation and accurate and reliable measuring result.

The invention relates to a method used for directly precipitating vanadium from an acid multi-impurity vanadium-containing solution. According to the technical scheme, the method includes the steps that an oxidizing agent is added into the vanadium-containing solution at first, oxidation is performed, and accordingly an oxidized vanadium solution is obtained; the addition amount of the oxidizing agent accounts for 1.0-2.5 times of the theoretical molar weight of an oxidizing agent required when low valent vanadium in the vanadium-containing solution is completely oxidized into pentavalent vanadium; then urea is added into the oxidized vanadium solution to be stirred according to the mass ratio of the urea to vanadium pentoxide in the oxidized vanadium solution being (3-20):1, solid-liquid separation is performed, and accordingly ammonium polyvanadate and vanadium precipitation mother liquor can be obtained; and afterwards, the ammonium polyvanadate is calcined for 0.5-3.0h at the temperature condition of 450-650 DEG C, and accordingly the vanadium pentoxide can be obtained. According to the chemical composition of the vanadium-containing solution, the vanadium concentration is larger than 6g/L, the aluminum concentration is smaller than 20g/L, the ferrum concentration is smaller than 1.0g/L, the sodium concentration is smaller than 30g/L, the potassium concentration is smaller than 2.0g/L, and the calcium concentration is smaller than 1.0g/L. The pH value of the vanadium-containing solution is smaller than 0.5. The method has the advantages that the technological process is short, the vanadium precipitating rate is high and the purity of the vanadium pentoxide product is also high.

The present invention proposes an aqueous pectin solution comprising Ca-reactive low-methoxylated-amidated fruit having a degree of methoxylation of 5% to 25% and a degree of amidation of 10% to 30%. Glue, the aqueous pectin solution has a calcium concentration of 9ppm or less, the viscosity of the aqueous pectin solution at 25°C is 1 to 30mPa.s, 100mL of the aqueous pectin solution contains 10mmol/L of calcium chloride, and 0.2mol/L of sodium citrate. The mixed solution of 200 mL of calcium/sodium aqueous solution in 1 L has a stable gel viscosity of 700-10000 mPa.S at 25° C., and the stable gel formation time is less than 3 minutes. In addition to all the advantages of the original pectin solution, the pectin solution also has higher calcium reactivity, higher anti-ionic strength damage, and more importantly, shorter reaction time and higher safety.

One aspect of this invention relates to a method and digester for reducing the deposition of calcium-based scale in a wood chip digester including extraction from the digester of first and second quantities of cooking liquor having respective first and second calcium concentrations, treating the extracted cooking liquors to produce a cooking liquor having a calcium concentration less that the calcium concentration of the either of the first and second extracted cooking liquors, and, reintroducing the treated cooking liquor to the digester. Another aspect of this invention relates to a method and digester in which through put through the digester is increased by the continuous addition of process liquor into the digester preferably at an upper region of the digester.

The present invention relates to a pharmaceutical composition or a kit comprising, a first substance capable of raising intracellular cAMP levels, and a second substance capable of modulating intracellular calcium concentration.

Likewise, the present invention relates to methods of treating patients suffering from autism spectrum disorder (ASD) phenotype 1 by administering an effective amount of a substance capable of raising intracellular cAMP levels and, optionally, an effective amount of a substance capable of modulating intracellular calcium concentration.

A method for preparing a vegetable nutriment includes the following steps: 1 fresh vegetables are chosen, washed, peeled and made into vegetable puree; 2 alginic acid solutions or alginate solutions and protein solutions are prepared and added into the vegetable puree prepared in step 1 for mixing to form the slurry; 3 coagulant solutions are made of soluble calcium salt and the calcium concentration is controlled between 0.12 percent and 1.03 percent; 4 the slurry and coagulant are mixed, stirred uniformly, then put into a mold of a mold making machine, pressure is added then the food with different shapes are formed; and 5 the food obtained in step 4 is processed through ultraviolet sterilization, then sealed, thus forming a product. The advantages are that the content of vitamins is high due to the main prepared materials which are vegetables; by using the protein of vegetables and animals which are extracted from the animals of cattle and marine lives and beans, the nutritive value is high and the use of chemical materials are reduced, thus reducing the cost and having high nutritive value.