51 results about "Carbohydrate derivative" patented technology

An antimicrobial composition, including a synergistic combination of three or more agents as an active ingredient. Each of the three or more potentiating agents can be selected from the following types of compounds: sequestering agents, carbohydrates and carbohydrate derivatives, terpenes/terpenoids, amines and amine derivatives, plant-derived oils, sulfonates, phenols, fatty acids, dibenzofuran derivatives, organo isothiocyanates, quaternary ammonium compounds, peroxides and peroxide donors, and macrolide polyenes. At least two of the three or more potentiating agents are not of the same type of compound. The antimicrobial composition can have strong antimicrobial efficacy in control of microorganisms having resistance to currently used antimicrobials.

The present invention relates to the use of a non-reducing carbohydrate or carbohydrate derivative and at least one agent which inhibits dimer formation in a freeze-dried composition comprising at least one peptide that contains a free cysteine residue, to provide a freeze-dried composition with improved long-term storage stability.

The invention relates to new etherified carbohydrate derivatives, a method for production thereof, pharmaceutical compositions containing the same and use for the production of a pharmaceutical preparation for treatment of conditions in which macrophages are stimulated or down-regulated. In an embodiment of the present invention, said carbohydrate derivatives comprise general formula (I) wherein n is an integer in the range from 3 to 98, and each group R independently represents a hydrogen atom or an aliphatic, saturated or unsaturated hydrocarbon chain having from 7 to 30 carbon atoms.

Provide is a cellulose acylate film, of which the environmental humidity-dependent retardation change is small and which, when stuck to a polarizer and used in high-temperature and high-humidity environments, is effective for preventing the polarizing element from being deteriorated. A cellulose acylate film, which contains a hydrogen-bonding compound satisfying the following requirements (A) to (C), and at least one hydrophobizing agent selected from a polyalcohol ester-base hydrophobizing agent, a polycondensate ester-base hydrophobizing agent and a carbohydrate derivative-base hydrophobizing agent: (A) the compound has both a hydrogen-bonding donor part and a hydrogen-bonding acceptor part in one molecule, (B) the value computed by dividing the molecular weight of the compound by the total number of the hydrogen-bonding donor number and the hydrogen-bonding acceptor number in the compound is from 30 to 65, and (C) the total number of the aromatic ring structures in the compound is from 1 to 3.

The invention discloses a making method of rhodium complex compound of imidazoline and coordination of carbohydrate derivant, which comprises the following steps: reacting N,N'-di (methyl 3-deoxygenation-4, 6-O-benzyl crossing base-alpha-D-altronic pyran glycoside-3-base) ethanediamine and 40 ml ammonium chloride in the triethoxymethane for 3-4. 2h; cooling; filtering; washing through petroleum ether to obtain chiral imidazoline ligand; blending the ligand and [RhCl(COD)]2 and NaOtBu to react in the 20ml THF for 48h at 45 deg. c; filtering; purifying through column chromatography to obtain the product as high-property catalyst.

Provided is an optical film, which is capable of fully keeping close cooperation between the active energy radial solidifying layer and the acylation cellulose membrane even exposed to sunlight for a long while. Even as polaroid protective film assembled to Polaroid and used for a long time at a high temperature, the optical film can still keep excellent polarization performance. Moreover, the thickness of the optical film is reduced. In addition, the invention also provides a polaroid and a liquid crystal display apparatus employing the optical film. The optical film of the invention is provided with an acylation cellulose membrane and an active energy radial solidifying layer. The acylation cellulose membrane comprises at least one plasticizer selected from the group consisting of a carbohydrate ramification, polyol ester, and contracting polyester. Moreover, the active energy radial solidifying layer comprises hindered amine compound.

The invention belongs to the field of chemical pharmaceutical technology, particularly relates to drug design of the traditional Chinese medicine extract shikonin serving as a lead compound and related research of anti-tumor activity. Carbohydrates are led into the framework molecule of the shikonin by means of chemical synthesis so as to obtain carbohydrate derivative with novel structure, and the research of in-vitro anti-tumor activity shows that the inhibition activity of the glycosyl shikonin on tumor cell A549 is obviously better than that of NCI-H460. From the activity result, the glycosyl shikonin can be prepared into anti-tumor medicament with high effect and low toxicity.

A method for the synthesis of a fucooligosaccharide glycosides by reacting a fucosyl donor with H-A-R₁ or a salt thereof, wherein A and R₁ are as defined herein, under the catalysis of an enzyme capable of transferring fucose is provided. The fucooligosaccharid glycoside compounds, or derivatives thereof, their use in the manufacture of human milk oligosaccharides, and a method of manufacture of human milk oligosaccharides, are also provided.

A cellulose acylate film containing a cellulose acylate and a carbohydrate derivative satisfying that the Clog P value thereof is from 0 to 5.5 and the maximum value of the molar extinction coefficient thereof in a wavelength range of from 230 nm to 700 nm is at most 50×10³, wherein the hydroxyl groups in the carbohydrate derivative are substituted with at least two types of substituents and at least one of the substituents has at least one aromatic ring, and wherein the carbohydrate derivative is contained in an amount of from 1 part by mass to 30 parts by mass relative to 100 parts by mass of the cellulose acylate therein has a low water content, capable of preventing the deterioration of polarizer when it is stuck to polarizer and aged in high-temperature and high-humidity environments, having good optical characteristics expressibility and having a low haze.

A binder for coating slips is disclosed comprising a first binder component, the first binder component providing the solids content of gelatine in the binder, one or more father binder components which are selected from the group consisting of vinyl alcohol polymers vinyl alcohol copolymers, carbohydrates, and carbohydrate derivatives, the one or more further binder components providing, summed together, the solids content of the one or more further binder components in the binder; the solids content of the gelatine in the binder being greater than the solids content of the one or more further binder components in the binder.

A composition comprising at least two glycoalkaloids of formula I:

wherein: either one or both of the dotted lines represents a double bond, and the other a single bond, or both represent single bonds;

A: represents a radical selected from the following radicals of general formulae (II) to (V):

• • each of R¹ is a radical separately selected from the group consisting of hydrogen, amino, oxo and OR⁴;
  • each of R² is a radical separately selected from the group consisting of hydrogen, amino and OR⁴;
  • each of R³ is a radical separately selected from the group consisting of hydrogen, carbohydrate and a carbohydrate derivative;
  • “X” is a radical selected from the group comprising —CH₂—, —O— and —NH₂—; and
  • wherein the compound includes at least one R⁴ group that is a carbohydrate or a derivative thereof selected from the group comprising glyceric aldehyde, glycerose, erythrose, threose, ribose, arabinose, xylose, lyxose, altrose, allose, gulose, mannose, glucose, idose, galactose, talose, rhamnose, dihydroxyactone, erythrulose, ribulose, xylulose, psicose, fructose, sorbose, tagatose, and other hexoses, heptoses, octoses, nanoses, decoses, deoxysugars with branched chains, (e.g. apiose, hamamelose, streptose, cordycepose, mycarose and cladinose), compounds wherein the aldehyde, ketone or hydroxyl groups have been substituted (e.g. N-acetyl, acetyl, methyl, replacement of CH₂OH), sugar alcohols, sugar acids, benzimidazoles, the enol salts of the carbohydrates, saccharinic acids, sugar phosphates; wherein the ratio of said glycoalkaloids is between 6:1 and 1:6 and on the proviso that when the glycoalkaloids are solamargine and solasonine and they are present in a 1:1 ratio the solamargine and solasonine are isolated.

A method of oxidising carbohydrates and/or carbohydrate derivatives having primary alcohol groups comprising contacting a reaction medium containing said carbohydrates and/or carbohydrate derivatives with a nitroxy radical mediator and a peroxidase enzyme, characterised in that the initial reaction medium contains at least 10% by weight carbohydrates and/or carbohydrate derivatives, in that the peroxidase enzyme is an oilseed peroxidase and in that a hydroperoxide and an alkali compound are gradually added to the reaction medium such that its pH is maintained at between 3.5 and 10.0 (pH-Stat); use of said method in a process for producing gluconic acid, glucaric acid and/or D-glucuronolactone.

The invention discloses a method for regenerating reducing sugar from a hydrazine chromophoric reagent derivative of the reducing sugar. The method comprises the following steps: 1) taking the reducing sugar, adding a hydrazine chromophoric reagent with an amount of a mole number being no less than 10 times of the reducing sugar, then dissolving the materials in a weak acid aqueous solution of anorganic solvent, uniformly shaking the materials, heating the materials for a reaction, after the reaction is completed, performing condensation drying; 2) adding water in a sample obtained in the step 1) for dissolving, then using the organic solvent for extraction, or passing the material through a C18 column and/or a PGC solid-phase extraction column for purification; 3) separating the sample obtained in the step 2) through a chromatography; and 4) separating a single carbohydrate derivative collected in the step 3) for drying, then dissolving the material in the weak acid aqueous solution,removing a hydrazine chromophoric reagent tag under heating condition, and regenerating a reducing sugar chain. The method has the beneficial effects that the operation is simple, the reaction is mild and fast, and the generated reducing sugar chain monomer has no generated side reaction products, and the recovery rate is high.

The invention discloses a carbohydrate derivant, complex compound and making method with coordination Pt complex compound of cancer resistant, which is characterized by the following: reacting primary diamine 2,3-anhydride-alpha-D-manna pyran glycoside to obtain the diamine; making the diamine and Pt salt to obtain the Pt complex compound of coordinated nitrogen atom; making single Pt complex compound coordinated by diamine and diPt complex compound coordinated by bridged diamine and alkali additional salt; fitting for the drug composition to treat cancer.

Disclosed are super-hydrophobic, super oleophilic membranes comprising a metal mesh comprising copper, a coating comprising a carbohydrate derivative, wherein the carbohydrate derivative is covalently or ionically bonded to a metal mesh surface and methods of preparation thereof. The disclosed membranes are useful for wastewater treatment in the oil industry, in particular for oil/water separation processes.