The present invention discloses novel dual prodrug compositions of Formula 1,
wherein A is a single bond, —O—, or —CH2—; m and n vary from 0 to 15; p and q vary from 0 to 4; B is a single bond or —CR3R4; D is selected from the group consisting —CO2R5, —OR6, —OCOR7, —SO3R8, —SO2NH2, —OPO(OR9)(OR10), —OPO(OR9)(NH2), —OPO(OR9)—O—PO(OR10)(OR11),
R1 to R11 are various substituents selected to optimize the physicochemical and biological properties such as, lipophilicity, toxicity, bioavailability, and pharmacokinetics of compounds of Formula 1. These compounds are useful for the treatment of various cardiovascular and neurological disorders.