The application discloses a primer group, a kit and application for screening
autism spectrum disorder patients, and belongs to the field of
disease diagnosis. The technical problem solved by the application is how to screen
autism spectrum disorder patients in
Chinese Han population. The primer group for screening
autism spectrum disorder patients disclosed by the application is directed to 132 autism susceptible
gene sites, and is composed of 264 single-stranded DNAs shown in SEQ ID No. 1 to SEQ ID No. 264. According to the 132 autism susceptible
gene sites, a
data model is established by SVM,
autism spectrum disorder patients can be screened, and the
data model has good accuracy, precision,
recall rate, F1
score and AUC value, can provide stable and efficient prediction performance between balanced
precision and recall rate, and has strong ability in distinguishing
autism spectrum disorder patients and
healthy individuals.