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30 results about "Cycloalliin" patented technology

Post-modified imine-COF adsorbent as well as preparation method and application thereof

The invention relates to the technical field of adsorption materials, and discloses a post-modified imine-COF adsorbent and a preparation method and application thereof, the adsorbent comprises the following structural units: a COF skeleton, which is a two-dimensional or three-dimensional porous skeleton formed by an aromatic aldehyde monomer and an amino monomer through a Schiff base reaction; the imine group is formed in a COF skeleton through a post-modification reaction, and the imine group is-C = NR, r is selected from one or more of a substituted or unsubstituted alkyl group, a substituted or unsubstituted cycloalkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted cycloalkenyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted heterocyclic group and a hydrogen atom. The adsorbent retains excellent structural characteristics of the COF material, realizes high density and uniform distribution of functional groups, and avoids interference of functional monomers on crystal nucleation and growth, so that the adsorption performance of the adsorbent is improved, and the adsorbent can efficiently capture rare earth when being applied to a rare earth-containing solution.
Owner:NANCHANG UNIV

Polymer, photoresist composition containing the same, and pattern forming method

[Problem] To provide a polymer, a photoresist composition containing the same, and a pattern forming method. [Solution] A polymer comprising a first repeating unit containing a sulfone group directly bonded to a group of formula -C(Ra)(Rb)-, and a second repeating unit containing an acid-unstable group, a base-degradable group, a polar group, or a combination thereof, wherein Ra and Rb in the formula are each independently hydrogen, halogen, substituted or unsubstituted C1-30 alkyl, substituted or unsubstituted C3-30 cycloalkyl, substituted or unsubstituted C3-30 heterocycloalkyl, substituted or unsubstituted C2-30 alkenyl, substituted or unsubstituted C3-30 cycloalkenyl, substituted or unsubstituted C3-30 heterocycloalkenyl, substituted or unsubstituted C6-30 aryl, substituted or unsubstituted C7-30 arylalkyl, substituted or unsubstituted C7-30 alkylaryl, substituted or unsubstituted C2-30 heteroaryl, substituted or unsubstituted C3-30 heteroarylalkyl, or substituted or unsubstituted C3-30 alkylheteroaryl, but at least one of Ra and Rb is hydrogen.
Owner:DUPONT ELECTRONIC MATERIALS INT LLC

Pyridyl-substituted heterocyclic compound, preparation method thereof, insecticidal composition and application of pyridyl-substituted heterocyclic compound

The invention belongs to the technical field of pesticides, and particularly relates to a pyridyl-substituted heterocyclic compound, a preparation method thereof, an insecticidal composition and application. The compound is shown as a general formula I, wherein Q1 represents NR7 or O; q2 represents N, CH or C-halogen; x represents a cycloalkyl group, a cycloalkenyl group, an aryl group or a heterocyclic group; y represents an alkyl group, an alkenyl group, an alkynyl group, a haloalkyl group or the like; r1 represents hydrogen, halogen, alkyl, alkenyl or the like; r2 and R3 each independently represent hydrogen, halogen, cyano, or the like; and n represents 0, 1 or 2. The compound has excellent prevention and treatment effects on spodoptera frugiperda, armyworms and the like.
Owner:QINGDAO KINGAGROOT CHEM COMPOUNDS CO LTD

Use of a merocyanine to photostabilize resveratrol and / or a derivative thereof

The invention therefore relates to the use of (i) one or more merocyanine(s) of formula (3) below and also the E / E or E / Z geometric isomer forms thereof, and the tautomers thereof, the salts thereof, and the solvates thereof such as hydrates, in which formula (3): A is -O- or -NH; R is a C1-C22 alkyl group, a C2-C22 alkenyl group, a C2-C22 alkynyl group, a C3-C22 cycloalkyl group or a C3-C22 cycloalkenyl group, it being possible for said groups to be interrupted by one or more O; for (photo)stabilizing (ii) resveratrol, a derivative thereof and also the geometric isomer forms thereof, the salts thereof and the solvates thereof such as hydrates, or mixtures thereof.
Owner:LOREAL SA

Silicon compound and method of manufacturing integrated circuit device using the same

A silicon compound, a composition, and associated methods, the silicon compound being represented by Chemical Formula (1):R1m(OR2)n(OR3)3-m-nSi—O—SiR4p(OR5)q(OR6)3-p-q,  Chemical Formula (1)wherein, in Chemical Formula (1), m, n, p, and q are each independently an integer of 0 to 3, and satisfy the following relations m+p≥1, m+n≤3, and p+q≤3, R1 is a heterocyclic group, R4 is a heterocyclic group, a carbon saturated group, or a carbon unsaturated group, and R2, R3, R5, and R6 are each independently a hydrogen atom, a C1-C7 alkyl group, a C2-C7 alkenyl group, a C3-C7 cycloalkyl group, or a C3-C7 cycloalkenyl group.
Owner:SAMSUNG ELECTRONICS CO LTD +1

Ionizable lipids, stereoisomers or pharmaceutically acceptable salts thereof, and uses thereof

The application provides an ionizable lipid, a stereoisomer or a pharmaceutically acceptable salt thereof and application thereof and application thereof in preparation of a lipid nanoparticle, an mRNA drug, and has the structure shown in the following formula: wherein X is a 4-10 membered heterocycle containing one or more heteroatoms of nitrogen, sulfur and oxygen; Y is selected from -C- or N; G1, G2, G3, G4 and G5 are each independently a single bond, -O(C=O)- or the like; L1, L2, L3, L4, L5, L6 and L7 are each independently a divalent linking group or null, and the divalent group has the structure of - (L a -L b -L c ) -, wherein L a and L c are the same or different and are each independently a substituted or unsubstituted C1-C 12 alkylene or the like; R1, R2 and R3 are each independently H, a 4-10 membered heterocycle containing one or more heteroatoms of nitrogen, sulfur and oxygen, a substituted or unsubstituted C1-C 24 alkylene containing or not containing one or more heteroatoms of nitrogen, sulfur and oxygen, C2-C 24 alkenylene, C3-C8 cycloalkylene or C3-C8 cycloalkenylene, wherein the substituent is a hydrocarbon group, a carboxyl group, an acyl group or an alkoxy group. The technical scheme of the application has the characteristics of high delivery efficiency, high transfection efficiency, low toxicity, safety and effectiveness.
Owner:SHANGHAI INST OF CERAMIC CHEM & TECH CHINESE ACAD OF SCI +1

New boron derivatives, their preparation process and their use

The invention relates to a compound of the following formula (I): in which i+j+k+l = 3, i = 0 or 1, j = 0 or 1, k = 0 or 1 and l = 0 or 1, in which R1 and R2, identical or different, independently represent in particular: an alkyl group of 1 to 8 carbon atoms, a cycloalkyl or cycloalkenyl group of 3 to 8 carbon atoms, in which R3 and R4, identical or different, independently represent in particular: an alkyl group of 1 to 8 carbon atoms, a cycloalkyl or cycloalkenyl group of 3 to 8 carbon atoms, in which the groups R1 and R2 or the groups R3 and R4 or the groups R1 and R4 are optionally covalently linked together, and in which at least one of the groups R3 or R4 is photolabile.
Owner:UNIVERSITE DE BORDEAUX +2

Substituted pyridine compound, preparation method thereof, insecticidal composition and application

The invention belongs to the technical field of pesticides, and particularly relates to a substituted pyridine compound, a preparation method thereof, an insecticidal composition and application. The compound is shown as a general formula I, wherein X1 represents COR1,-S-alkylene-Q,-N (R2)-alkylene-Q or-O-alkylene-Q; x2 represents halogen; q represents a cycloalkyl group, a cycloalkenyl group, an aryl group or a heterocyclic group; r1 represents OR9, SR9 or NR7R8; r2 represents hydrogen or alkyl; m represents an aryl group or a heterocyclic group; y1 and Y2 each independently represent hydrogen, halogen, cyano, or the like; r7 and R8 each independently represent hydrogen, an alkyl group, an alkenyl group, or the like; r9 each independently represents hydrogen, an alkyl group, an alkenyl group, or the like; the compound has excellent prevention and treatment effects on brown planthopper, sogatella furcifera and the like.
Owner:QINGDAO KINGAGROOT CHEM COMPOUNDS CO LTD

Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element

The invention provides a liquid crystal alignment agent, a liquid crystal alignment film and a liquid crystal display element, and relates to the technical field of liquid crystal display materials. The liquid crystal aligning agent comprises (a) a polymer, wherein the polymer is selected from one or more of polyamic acid and imidization polymer; (b) a crosslinking agent having one or more groups selected from the group consisting of an epoxy group, a urea group, a hydroxyl group, and a polymerizable unsaturated bond; (c) the low-temperature curing accelerator has a general formula represented by a structural formula (1), in the structural formula (1), R1 and R3 are respectively and independently an amino group, a hydroxyl group, a sulfydryl group, a carboxyl group and a sulfo group, and R2 is a single bond, an unsubstituted or substituted C1-C6 alkyl group, an unsubstituted or substituted C2-C6 alkenyl group, an unsubstituted or substituted C2-C6 alkynyl group, a C3-C8 cycloalkyl group, a C3-C8 cycloalkenyl group, a C1-C6 alkoxy group and a C1-C6 alkylamino group. According to the liquid crystal alignment agent provided by the invention, the release speed of residual charges can be effectively increased, and the hardness of a liquid crystal alignment film is improved.
Owner:WUHAN ROUXIAN SCIENCE & TECHNOLOGY CO LTD +2

Biodegradable chelating agents and methods for fabric care

Biodegradable chelating agents comprising tropolone, derivatives of tropolone, and combinations and salts thereof can be incorporated into various fabric care compositions and delivery formats. A fabric care composition may comprise at least one component according to Formula 7, and combinations and salts thereof. (7) In Formula 7, R1 is a hydroxyl, C1-C6 carboxyl, linear or branched C1-C6 alkyl, linear or branched C2-C6 alkenyl, or linear or branched C2-C6 alkynyl group, a is 0-5, R2 is a condensed C1-C6 cycloalkyl, condensed C1-C6 cycloalkoxy, or condensed C1-C6 cycloalkenyl, b is 0-4, R3 is oxygen or hydroxyl, and c is 0-4. [Formula 1] JPEG2026520978000044.jpg34169
Owner:PROCTER & GAMBLE CO

Primary alkali metal cells with cyano-cycloalkenes additives

The present invention is related to a primary cell comprising at least one anode, with an alkali metal as active anode material, at least one cathode and an electrolyte comprising at least one additive. The aim to be achieved with the additive is comprising at least one additive is amongst other to prevent depositions of the active anode material on inner surfaces of the cell effectively. This is achieved by employing a cyano-cycloalkene with a ring comprising carbon atoms ranging from 3 to 15.
Owner:LITRONIK BATTERIETECHNOLOGIE GMBH

Modified poly(phenylene ether) copolymers, compositions, and methods thereof

ActiveUS12668663B2MethacrylatePolymer science
A poly(phenylene ether) copolymer comprising first repeating units comprising a C1-6alkyl(C6-30cycloalkenyl) pendant group; second repeating units different from the first repeating units; a copolymer of Formula (3); and optionally, at least one terminal functional group comprising (meth)acrylate, styrene, —CH2—(C6H4)—CH═CH2, allyl, cyanate ester, glycidyl ether, anhydride, aniline, maleimide, an activated ester, or a combination thereof.
Owner:SHPP GLOBAL TECH BV

Thiazolidine compounds for corrosion inhibition

The present invention relates to the use of a thiazolidine compound of the formula (I) for reducing or inhibiting surfaces corrosion, for example in applications such as water treatment, industrial cleaning and especially in automatic dishwashing (ADW). Moreover, the present invention also relates to a method for reducing or inhibiting surfaces corrosion using said thiazolidine compound. Furthermore, the present invention relates to specific thiazolidine compounds and to a process for producing these compounds. (I) wherein R1 is selected from the group consisting of hydrogen and C1-4-alkyl; R2 is selected from the group consisting of hydrogen, carboxyl, C1-10- alkoxycarbonyl, C1-20-alkyl, C2-10-alkenyl, where C1-20-alkyl and C2-10-alkenyl are unsubstituted or substituted by 1 or 2 of the groups Ra, etc.; R3 is selected from the group consisting of hydrogen and C1-4-alkyl; R4 is selected from the group consisting of hydrogen, NH-C(=O)-NH2 and C1-4- alkyl; X is selected from the group consisting of hydrogen, alkali metal ions, C1-20- alkyl, C2-10-alkenyl and C6-12-aryl-C1-4-alkyl, where C6-12-aryl is unsubstituted or substituted by 1, 2 or 3 substituents Rc; Ra is selected from the group consisting of COOH, OH, C1-10-alkoxycarbonyl, C1-10-alkylcarbonyl, C2-10-alkenyl, NHC(=O)Rd, C3-10-cycloalkyl, C6-10-bicyclo- alkyl, C5-10-cycloalkenyl, 5-or 6-membered heterocyclyl bearing 1 or 2 heteroatoms selected from O, S and N, where C3-10-cycloalkyl, C6-10-bicycloalkyl, C5-10-cycloalkenyl and heterocyclyl are unsubstituted or substituted by 1, 2 or 3 substituents Rb, C6-12-aryl, such as phenyl, and 5- or 6-membered hetaryl, such as furyl and pyridyl, where C6-12-aryl and hetaryl are unsubstituted or substituted by 1, 2 or 3 substituents Rc; Rb is C1-4-alkyl, OH or two groups Rb bound to the same carbon atom are =O; Rc is selected from the group consisting of OH, C1-4-alkyl and O-C1-4-alkyl; and Rd is selected from the group consisting of H and C1-4-alkyl.
Owner:BASF SE

Substituted pyridine compound and preparation method therefor, insecticidal composition, and use

The present invention relates to the technical field of pesticides, and particularly to a substituted pyridine compound and a preparation method therefor, an insecticidal composition, and a use. The compound is as represented by general formula I: formula I, wherein X1 represents COR1, -S-alkylene-Q, -N(R2)-alkylene-Q, or -O-alkylene-Q; X2 represents halogen; Q represents cycloalkyl, cycloalkenyl, aryl or heterocyclyl; R1 represents OR9, SR9, or NR7R8; R2 represents hydrogen or alkyl; M represents aryl or heterocyclyl; Y1 and Y2 each independently represent hydrogen, halogen, cyano, etc.; R7 and R8 each independently represent hydrogen, alkyl, alkenyl, etc.; and R9 each independently represents hydrogen, alkyl, alkenyl, etc. The compound has an excellent control effect on Nilaparvata lugens, Sogatella furcifera, etc.
Owner:QINGDAO KINGAGROOT CHEM COMPOUNDS CO LTD

Substituted pyridine compound, preparation method thereof, insecticidal composition and application

The invention belongs to the technical field of pesticides, and particularly relates to a substituted pyridine compound, a preparation method thereof, an insecticidal composition and application. The compound is shown as a general formula I, wherein L represents a direct bond,-O-,-S-,-NR8-, alkylene, alkenylene or alkynylene; r8 represents hydrogen or alkyl; q represents a cycloalkyl group or a cycloalkenyl group; m represents an aryl group or a heterocyclic group; x represents halogen; y1 and Y2 each independently represent hydrogen, halogen, cyano, or the like. The compound has excellent prevention and treatment effects on brown planthopper, sogatella furcifera and the like.
Owner:QINGDAO KINGAGROOT CHEM COMPOUNDS CO LTD

Use of a merocyanin to photostabilize resveratrol and / or one of its derivatives

Use of a merocyanin for photostabilizing resveratrol and / or one of its derivatives. The invention therefore relates to the use of (i) one or more merocyanins of the following formula (3) and their isomeric geometric forms E / E or E / Z, and their tautomers, salts, and solvates such as hydrates: [Formula 3] Formula 3 wherein: A is –O- or –NH; R is a C1-C22 alkyl group, a C2-C22 alkenyl group, a C2-C22 alcinyl group, a C3-C22 cycloalkyl group, or a C3-C22 cycloalkenyl group, said groups being able to be interrupted by one or more O groups, for (photo)stabilizing (ii) resveratrol, one of its derivatives, and their isomeric geometric forms, salts, and solvates such as hydrates or their mixtures.
Owner:LOREAL SA

A method for removing potassium from activated carbon by alkali based on copolymer gel

This invention discloses a method for potassium removal from alkaline activated carbon based on copolymer gel, belonging to the field of activated carbon technology. First, alkaline activated carbon and copolymer gel are mixed, and a surfactant is added for ultrasonic treatment to obtain a pretreated solution. The pretreated solution is then reacted at 20-30°C for 1.5-2.5 hours, followed by a reaction at 30-40°C for 45-65 minutes. Finally, CO2 is introduced until the pH reaches 7-7.5, and the system temperature is raised to 45-50°C for desorption. After desorption, CO2 is stopped, and the system is allowed to stand at 8-12°C to separate the precipitate. The precipitate is then washed and dried to obtain potassium-removed activated carbon. This invention creatively designs a copolymer gel that integrates crown ether and cycloene recognition sites and possesses temperature- and pH-responsive properties, enabling deep and selective removal of residual potassium ions from alkaline activated carbon under mild conditions, while avoiding damage to the carbon skeleton caused by strong acids and high temperatures.
Owner:广东韩研活性炭科技股份有限公司

Substituted aryl amide compound and application thereof

The invention belongs to the technical field of pesticides, and particularly relates to a substituted aryl amide compound and application thereof. The compound is shown as a formula I, wherein P is O or S; q is O, S, SO or SO2; x is an aryl group, a heterocyclic group, a cycloalkyl group or a cycloalkenyl group; r2 and R8 are each independently hydrogen, an alkyl group, an alkenyl group, an alkynyl group, or the like; r1, R3, R4, R5, R6, and R7 are each independently a hydrogen atom, a halogen atom, an alkyl group, an alkenyl group, or the like. The compound has an excellent bactericidal effect.
Owner:QINGDAO KINGAGROOT CHEM COMPOUNDS CO LTD

Pyridyl-substituted heterocyclic compound and preparation method therefor, insecticidal composition and use

PCT designated stageWO2026026182A1BiocideOrganic chemistryArylChemical compound
The present invention belongs to the technical field of pesticides, and specifically relates to a pyridyl-substituted heterocyclic compound and a preparation method therefor, an insecticidal composition and the use. The compound is represented by general Formula (I), wherein Q1represents NR7 or O; Q2 represents N, CH or C-halogen; X represents a cycloalkyl group, a cycloalkenyl group, an aryl group or a heterocyclic group; Y represents an alkyl group, an alkenyl group, an alkynyl group, a haloalkyl group, etc.; R1 represents hydrogen, halogen, an alkyl group, an alkenyl group, etc.; R2 and R3 each independently represent hydrogen, halogen, a cyano group, etc.; and n represents 0, 1 or 2. The compound has a good control effect on fall armyworms, armyworms, etc.
Owner:QINGDAO KINGAGROOT CHEM COMPOUNDS CO LTD

Use of a merocyanin to photostabilize resveratrol and / or one of its derivatives

Use of a merocyanin for photostabilizing resveratrol and / or one of its derivatives. The invention therefore relates to the use of (i) one or more merocyanins of the following formula (3) and their isomeric geometric forms E / E or E / Z, and their tautomers, salts, and solvates such as hydrates: [Formula 3] Formula 3 wherein: A is –O- or –NH; R is a C1-C22 alkyl group, a C2-C22 alkenyl group, a C2-C22 alcinyl group, a C3-C22 cycloalkyl group, or a C3-C22 cycloalkenyl group, said groups being able to be interrupted by one or more O groups, for (photo)stabilizing (ii) resveratrol, one of its derivatives, and their isomeric geometric forms, salts, and solvates such as hydrates or their mixtures.
Owner:LOREAL SA

A method for preparing barley alcohol-soluble protein particles and a method for preparing an oil-in-water emulsion.

This invention provides barley prolysin particles and their preparation method, as well as a method for preparing an oil-in-water emulsion, belonging to the field of food science and engineering technology. This invention employs proline endonuclease to enzymatically hydrolyze barley prolysin at a pH of 5.5-5.8, breaking it down into small-molecule barley prolysin polypeptides, thus reducing the size of the particles. Calcium ions in calcium chloride aqueous solution form coordination bonds with negatively charged groups such as carboxyl and hydroxyl groups on the barley prolysin polypeptide chain, regulating the charge distribution on the surface of the barley prolysin molecules and improving the dispersibility of the particles in water. Furthermore, the cycloalkenyl ether ketone active group in genipin molecules forms stable Schiff base covalent bonds with the free primary amino groups on the barley prolysin polypeptide chain, constructing a stable three-dimensional network structure and improving the thermal stability of the emulsion obtained from the barley prolysin particles.
Owner:INST OF AGRI PROD DEV & FOOD SCI TIBET ACAD OF AGRI & ANIMAL HUSBANDRY SCI LHASA PEOPLES REPUBLIC OF CHINA

ERK2 degraders

The present disclosure relates to compounds according to Formula I or a pharmaceutically acceptable salt and / or solvate thereof, as well as compositions including such compounds and uses thereof, where R1 is alkyl, cycloalkyl, cycloalkenyl, heterocyclyl, aryl, or heteroaryl; R2 is H, alkyl, halo, amino, amide, hydroxyl, or O-R5; R3 is alkyl, cycloalkyl, heterocyclyl, aryl, or heteroaryl; R4 is H or alkyl; R5 is alkyl, cycloalkyl, cycloalkenyl, heterocyclyl, aryl, or heteroaryl; Z1 is CH, N, or C-R6; Z2 is CH, N, or C-R7; Z3 is CH, N, or C-R8; and R6, R7, and R8 are each independently alkyl, cycloalkyl, halo, amino, amide, hydroxy, or alkoxy. As evidenced by this application, these compounds and compositions are suitable for, among other things, treating cancer.
Owner:MEMORIAL SLOAN KETTERING CANCER CENT +2

Iridoid glycoside crop yield increasing and efficiency improving fertilizer, and preparation method and application thereof

This invention provides a cyclohexene glycoside-based fertilizer for increasing crop yield and efficiency, its preparation method, and its application. The method first prepares an aqueous solution of the cyclohexene glycoside substrate, and then prepares a nutrient matrix consisting of at least two of nitrogen, phosphorus, and potassium components mixed with an organic carrier. Next, nutrient-converting functional bacteria and cyclohexene glycoside-activating functional bacteria are separately cultured and then compounded to form a synthetic bacterial agent with specific β-glucosidase activity and an effective viable count. The cyclohexene glycoside substrate is then loaded onto diatomaceous earth particles with high open porosity to obtain a stabilized carrier. Subsequently, the carrier, nutrient matrix, and synthetic bacterial agent are mixed, and granulated under the condition of adding a binder to obtain wet granules. Finally, the granules are dried at low temperature in two stages until the moisture content is ≤8 wt%, and then granulated to obtain the finished fertilizer. This fertilizer integrates the active components of cyclohexene glycosides, compound nutrients, and functional microorganisms, which can synergistically promote crop growth and nutrient utilization, and is suitable for a variety of crops, achieving increased yield and efficiency.
Owner:HUBEI FUYINGMEN SPECIAL FERTILIZER CO LTD

Substituted pyridine compound and preparation method therefor, insecticidal composition and use

In the technical field of pesticides, specifically relating to a substituted pyridine compound and a preparation method therefor, an insecticidal composition, and a use. The compound is represented by the general formula (I); L represents a direct bond, -O-, -S-, -NR8-, an alkylene group, an alkenylene group, or an alkynylene group; R8 represents hydrogen or an alkyl group; Q represents a cycloalkyl group or a cycloalkenyl group; M represents an aryl group or a heterocyclic group; X represents a halogen; and Y1 and Y2 each independently represent hydrogen, a halogen, a cyano group, or the like. The compound exhibits excellent control effects against brown planthoppers, white-backed planthoppers, and the like.
Owner:QINGDAO KINGAGROOT CHEM COMPOUNDS CO LTD

A traditional Chinese medicine lycium fruit extract, a preparation method and use thereof

PendingCN122624563ABiotechnologyLycium
The application discloses a traditional Chinese medicine extract of Ligustrum lucidum and a preparation method and application thereof. The traditional Chinese medicine extract of Ligustrum lucidum contains total flavones, total iridoid glycosides and total phenylethanoid glycosides, and the content of each of them is greater than or equal to 3% in mass. The application adopts supercritical extraction or subcritical extraction to obtain a Ligustrum lucidum extract which is different from main components of a related product of Ligustrum lucidum which has been marketed at present. The extract has a significant prevention and treatment effect on an animal model related to MASLD, and can be developed into a new traditional Chinese medicine for effectively preventing and treating MASLD.
Owner:SICHUAN ACAD OF CHINESE MEDICINE SCI

Novel spiro compound

The present invention provides a novel spiro compound or a pharmacologically acceptable salt thereof that has a TRH-DE inhibitory activity and is useful for preventing or treating various diseases associated with TRH and / or symptoms associated therewith, a method for producing the same, a use thereof, and a pharmaceutical composition containing the compound or the pharmacologically acceptable salt thereof as an active ingredient.There is provided a compound represented by the following Formula [I]:wherein,a ring A represents an aryl group which may be substituted, a heteroaryl group which may be substituted, or an aliphatic heterocyclyl group which may be substituted, andR1 and R2 represent, independently, an alkyl group which may be substituted, a cycloalkyl group which may be substituted, an alkenyl group which may be substituted, a cycloalkenyl group which may be substituted, an alkynyl group which may be substituted, an aryl group which may be substituted, a heteroaryl group which may be substituted, an aliphatic heterocyclyl group which may be substituted and may have a double bond in a part of a ring, an amino group which may be substituted, an alkoxy group which may be substituted, or an alkylthio group which may be substituted, or a group in which R1 and R2 together form a ring,or a pharmacologically acceptable salt thereof.
Owner:TANABE PHARMA CORP

Polymer, photoresist compositions including the same, and pattern formation methods

ActiveUS12675045B2ArylPolymer science
A polymer, including a first repeating unit comprising a sulfone group, wherein the sulfone group is directly bonded to a group of formula —C(Ra)(Rb)—; and a second repeating unit comprising an acid labile group, a base-decomposable group, a polar group, or a combination thereof, wherein Ra and Rb are each independently hydrogen, halogen, substituted or unsubstituted C1-30 alkyl, substituted or unsubstituted C3-30 cycloalkyl, substituted or unsubstituted C3-30 heterocycloalkyl, substituted or unsubstituted C2-30 alkenyl, substituted or unsubstituted C3-30 cycloalkenyl, substituted or unsubstituted C3-30 heterocycloalkenyl, substituted or unsubstituted C6-30 aryl, substituted or unsubstituted C7-30 arylalkyl, substituted or unsubstituted C7-30 alkylaryl, substituted or unsubstituted C2-30 heteroaryl, substituted or unsubstituted C3-30 heteroarylalkyl, or substituted or unsubstituted C3-30 alkylheteroaryl, provided that at least one of Ra and Rb is hydrogen.
Owner:DUPONT ELECTRONIC MATERIALS INT LLC

Compounds

A compound of formula (I), or a pharmaceutically acceptable salt or hydrate thereof, is provided, wherein X-Y is -NHSO₂-. A is selected from C₄-C₈ cycloalkyl, bicyclic C₅-C₁₂ cycloalkyl, or a C₄-C₈ cy
Owner:GREY WOLF THERAPEUTICS LTD

Flavor substance directional regulation and control enzymolysis method for rehmannia and Chinese yam fermented beverage

The invention discloses a flavor substance directional regulation and control enzymolysis method for a rehmannia and Chinese yam fermented beverage, which comprises the following steps: S1, gelatinizing rehmannia and Chinese yam at high temperature; s2, cooling the gelatinized slurry, putting the gelatinized slurry into an enzymolysis bin of fermentation equipment, adjusting the gelatinized slurry to be acidic, and adding beta-glucosidase for enzymolysis; s3, conveying the enzymolysis slurry to a fermentation bin of fermentation equipment, and then adding lactic acid bacteria for anaerobic fermentation; s4, after the acidity of the fermentation liquor is further reduced, saccharomycetes are added, and double-bacterium anaerobic fermentation is carried out at low temperature; and S5, after fermentation is completed, performing pasteurization, filtration and aging, and then performing filling. The beta-glucosidase is used for performing directional enzymolysis on iridoid glycoside flavor substances such as catalpol and the like, the problem that the fermented beverage has bitter taste is solved, double-bacterium combined aeration is subsequently used for fermentation, breeding of infectious microbes is inhibited, and the taste of the beverage is enriched by generated various lipid substances.
Owner:CHINA PHARM UNIV

Substituted aryl amide compound and use thereof

PCT designated stageWO2026046181A1BiocideSilicon organic compoundsArylHalogen
The present invention belongs to the technical field of pesticides. Provided are a substituted aryl amide compound and the use thereof. The compound is as shown in formula I: (I), wherein P is O or S; Q is O, S, SO or SO2; X is an aryl, heterocyclyl, cycloalkyl or cycloalkenyl; R2 and R8 are each independently hydrogen, an alkyl, an alkenyl, an alkynyl, etc.; and R1, R3, R4, R5, R6 and R7 are each independently hydrogen, halogen, an alkyl, an alkenyl, etc. The compound has an excellent bactericidal effect.
Owner:QINGDAO KINGAGROOT CHEM COMPOUNDS CO LTD