4 results about "Drug/agent" patented technology

The utility model relates to the technical field of medicament mixing assistors, and discloses a double-component medicament opposite-extrusion mixing assistor which comprises a transverse plate, a transverse plate and a transverse plate, the two fixed seats are oppositely mounted on two sides of one end of the transverse plate; the extrusion roller is rotationally mounted between the two fixed seats through a rotating shaft; the clamping groove is formed in the outer wall of the extrusion roller in the axial direction of the extrusion roller; and the pressing mechanism is arranged in the clamping groove and used for pressing the bag tail in the clamping groove. According to the double-component medicament opposite-extrusion mixing assist device, the tail part of a medicament bag is fixed in the clamping groove, and when the extrusion roller rotates, the extrusion force generated when the bottom of the medicament bag penetrates through a gap between the extrusion roller and the transverse plate is utilized, so that the medicament bag can be uniformly extruded, time and labor are saved, and the mixing efficiency of the double-component medicament is improved.

The present disclosure describes a lipid-polymer hybrid nanoparticle and a method of synthesizing such a nanoparticle or a composition containing such a nanoparticle. These nanoparticles are made from a biodegradable polymer-based micellar core surrounded by a lipid-based shell, wherein a majority of the agent is present on the inner periphery of such nanoparticles due to physical adhesion to lipid molecules. Only a small amount of medicament is encapsulated in the micelle core. Thus, the lipid-based shell becomes the primary excipient part of the nanoparticle, and the core containing the biodegradable polymer becomes the secondary excipient part of the nanoparticle.

The present application relates to the technical field of biotechnology, and aims to provide a Bacteroides uniformis with activity against porcine epidemic diarrhea virus and application thereof. The strain is preserved in China Center for Type Culture Collection, and the preservation name is Bacteroides uniformis ZJNB01, the Latin name is Bacteroides uniformis, and the preservation number is CCTCC NO: M 20241757. The porcine-derived Bacteroides uniformis has significant probiotic properties; due to rapid growth, it has strong resistance to porcine epidemic diarrhea virus. The Bacteroides uniformis and / or its metabolites can be used as a drug active center to produce a drug agent, and have a wide application scenario in the prevention and treatment of porcine epidemic diarrhea virus.

This disclosure provides an iontophoresis drug delivery device. The iontophoresis drug delivery device includes: a power source for generating pulsed direct current required to penetrate a drug agent into a drug delivery area of ​​a biological organism, wherein the power source generates a positive pulsed direct current in a first time period and a reverse pulsed direct current in a second time period; a dielectric layer for contacting the drug delivery area, wherein the dielectric layer includes or has an active agent attached thereto, the active agent being used to penetrate into the drug delivery area via the pulsed direct current; and at least two electrodes for receiving the pulsed direct current output from the power source to provide the received pulsed direct current to the dielectric layer. The iontophoresis drug delivery device provided by this disclosure not only improves transdermal efficiency but also minimizes skin irritation or damage.