3 results about "Fructosamine" patented technology

This disclosure relates to a method for evaluating the efficacy of treatment with ranifibranol in patients with liver disease, the method comprising: a) measuring in vitro the levels of a combination of biomarkers consisting of CK18M65, hyaluronic acid, fructosamine, and ALT in a biological sample obtained from a patient; and b) evaluating the efficacy of treatment with ranifibranol according to the levels measured in step a).

The invention provides an extraction composition of camellia oleifera flowers, camellia oleifera shells and camellia oleifera seed shells and application of the extraction composition in anti-aging. The extraction composition comprises the camellia oleifera flower alcohol extract, the camellia oleifera shell alcohol extract and the camellia oleifera seed shell alcohol extract according to the mass ratio of (1-4): (1-4): 1, hyaluronidase can be remarkably inhibited, the excellent anti-aging effect is achieved, generation of initial-stage product fructosamine and final-stage product AGEs of protein non-enzymatic glycosylation can be remarkably inhibited, and the anti-aging effect is good. The whole-process anti-aging effect from early prevention to later repair is realized. In addition, the extracted composition is analyzed by applying a medium effect principle, and the three components in the extracted composition are found to play a synergistic effect in the anti-aging aspect.

The invention relates to the technical field of biological detection, and discloses a glycosylated protein fluid, a preparation method and application thereof and a fructosamine detection kit.The preparation method comprises the following steps that human serum albumin, bovine serum albumin and glucose with the mass ratio being (70-80): (20-30) are added into a buffer solution with the pH ranging from 7.0 to 8.0, incubation is conducted for 14 days to 28 days at the temperature of 36 DEG C to 38 DEG C in a dark place, an obtained reaction solution is purified, and the glycosylated protein fluid is obtained. A glycosylated protein solution is obtained; the ratio of the total protein mass to the glucose mass is 2: 1. The specific proportion of the human serum albumin and the bovine serum albumin can generate a synergistic effect, and an optimal balance is achieved between reduction of a heterologous matrix effect and improvement of stability, so that a calibrator prepared from the glycosylated protein liquid can simultaneously and remarkably improve the correction capability on reagent batch difference and instrument difference. Meanwhile, by controlling the pH value, the temperature and the time and adopting a purification process, the glycosylated protein fluid can have good stability.