12 results about "Galactosides" patented technology

The invention belongs to the technical field of aquaculture, and particularly relates to a feed additive for aquaculture as well as a preparation method and application of the feed additive. The preparation method of the feed additive comprises the following steps: (1) weighing the raw material medicines, adding water for soaking, boiling with strong fire, then decocting with slow fire, and collecting first filtrate and first filter residues; (2) adding water into the first filter residue, boiling with strong fire, decocting with slow fire, collecting a second filtrate, and concentrating to obtain a traditional Chinese medicine composition extracting solution; (3) adding yeast powder, peptone, dipotassium phosphate, inositol galactoside and 1, 3-diphosphoglyceric acid into the traditional Chinese medicine composition extracting solution to obtain a fermentation culture medium; and (4) inoculating the lactobacillus fermentum liquid and the bacillus subtilis liquid into the fermentation culture medium for fermentation to obtain a fermentation mixture, and performing centrifugation and freeze drying to obtain the lactobacillus fermentum and bacillus subtilis compound feed. The feed additive for aquaculture is added into feed, so that the growth and development capability of animals can be effectively promoted, the immunocompetence of the animals is improved, and the feed additive has a wide application prospect.

This invention discloses a firming and wrinkle-reducing eye cream, comprising a moisturizer, a whitening agent, a skin repair additive composition, a thickener, a preservative, a film-forming agent, a skin moisturizer, and a surfactant. The weight ratio of the moisturizer, whitening agent, anti-aging additive composition, thickener, preservative, film-forming agent, skin moisturizer, and surfactant is 20:1:2:3:0.3:0.5:1:0.2. The moisturizer includes butylene glycol, glycerin, polydimethylsiloxane, and hydrogenated polyisobutylene. The skin-repairing additive composition includes hydroxypropyl tetrahydropyranotriol, adenosine, cell growth factors, ceramides, and salicylic acid, comprising olefins, betaine, trehalose, 1,2-hexanediol, hydrogenated lecithin, allantoin, and Euglena galactosides. The film-forming agents include polyacrylamide, cyclohexylsiloxane, and polydimethylsiloxane alcohol. The emollients include C13-14 isoparaffins, polydimethylsiloxane / vinyl dimethylsiloxane crosspolymers, and cyclopentamethoxysiloxane. This invention can repair cells and provide long-lasting anti-wrinkle and whitening protection for the corners of the eyes.

The invention discloses an intestinal tract hemostatic composition as well as a preparation method and application thereof, and relates to the field of hemostatic drugs. Wherein the catechin, the hyperoside, the isoquercitrin, the quercetin-3-O-glucuronide, the gallocatechin, the myricetin-3-O-galactoside, the proanthocyanidin B1, the proanthocyanidin B3, the syringe-3-O-glucoside and the astragalus smicus glycoside are flavonoid compounds; nuciferine, higenamine, N-methyl-higenamine and N-trans-feruloyl tyramine are taken as alkaloid compounds, and the compound is selected from the group consisting of higenamine, nuciferine, higenamine The composition has the advantages of simple preparation process, good hemostatic effect and the like, and provides a new raw material choice for the development of intestinal bleeding treatment medicines.

The present application relates to a kind of methods for synthesizing alkyl galactoside using immobilized cells with monosaccharide as glycosyl donor.The method comprises the following steps: (1) culturing beta-galactosidase-producing yeast; (2) treating the yeast cells with ethanol; (3) adding genipin to the ethanol-treated yeast cells to construct a cross-linking system; reacting the cross-linking system for 0.5-4 h, centrifuging to obtain immobilized cells; (4) mixing galactose and alkyl alcohol uniformly, adding the immobilized cells, reacting for 2-16 h, centrifuging to separate the solid and liquid, taking the supernatant to obtain alkyl galactoside. The present application provides a green and efficient method for synthesizing alkyl galactoside, which is the first time to use immobilized yeast cells to synthesize glycoside with monosaccharide as glycosyl donor. The reaction system only contains alkyl glycoside and residual substrate after completion, the product types are few, easy to purify, suitable for large-scale synthesis of alkyl glycoside, and has broad application prospects.

The invention relates to the technical field of microbial culture, in particular to a klebsiella pneumoniae chromogenic medium as well as a preparation method and application thereof. The klebsiella pneumoniae chromogenic medium is prepared from the following raw materials: a core nutrient component, a composite salt system, a synergistic compound chromogenic system, a targeted composite antibacterial agent, a function enhancer, agar and deionized water, the synergistic compound color developing system comprises a composite color developing agent and a color developing synergist, wherein the composite color developing agent is prepared from 5-bromo-4-chloro-3-indole-beta-D-galactoside, indole acetate and naphthol-AS-D-acetate according to the weight ratio of (3.5 to 4.5) to (2.5 to 3.5) to (2.5 to 3.5); the targeted composite antibacterial agent comprises penicillin antibiotics and erythromycin in a weight ratio of (5-8): (2-4). The comprehensive advantages of high separation positive rate, comprehensive infectious microbe inhibition, high color development specificity, outstanding anti-interference capability and excellent stability are realized.

The invention discloses a citron leaf scalp care solution as well as a preparation method and application thereof, and the citron leaf scalp care solution is prepared from the following components in percentage by weight: 2.5 to 3.5 percent of citron leaf extract, 0.8 to 1.2 percent of tea tree essential oil, 0.6 to 1.0 percent of rosemary extract, 0.5 to 0.8 percent of pyridinone zinc butyrate, 1.0 to 2.0 percent of panthenol, 1.5 to 2.5 percent of nicotinamide, 1.0 to 1.5 percent of trehalose, 0.2 to 0.5 percent of beta-glyceryl alcohol, 3.0 to 5.0 percent of phosphatidosome, 2.0 to 3.0 percent of galactoside, 1.5 to 2.5 percent of polysorbate-20 and the balance of water. According to the present invention, 100% of the perfumed soap comprises, by weight, 3.0-4.0% of plant glycerin, 2.0-3.0% of propylene glycol, 0.3-0.5% of xanthan gum, 0.05-0.1% of quercetin, 0.1-0.2% of vitamin E, 0.05-0.1% of EDTA disodium, a proper amount of citric acid to adjust the pH value to 5.0-5.5, and the balance purified water;

The invention discloses a liver-targeted sorafenib prodrug as well as a preparation method and application thereof, and relates to the field of chemical pharmacy, the liver-targeted sorafenib prodrug is simple to prepare, sorafenib is selected as a core drug component, and the sorafenib is covalently linked with beta-galactoside. Due to the hydrophilicity of the beta-galactoside and the existence of a plurality of hydroxyl groups, after the sorafenib which is originally poor in solubility in water is covalently connected with the beta-galactoside, the solubility of the sorafenib is greatly improved. Due to the characteristic, the preparation process of the medicine is simplified, and a good foundation is laid for application of subsequent medicine in a solution system and in-vivo transportation and absorption. The molecular structure of the prepared liver targeting sorafenib prodrug S-Gal contains a galactoside bond. When the S-Gal enters a body, the S-Gal can be actively taken by ASGPR on the surface of a hepatoma carcinoma cell, and is hydrolyzed under the action of beta-Gal over-expressed in the cell to release a sorafenib raw drug, so that the liver targeting of the drug is enhanced, and the systemic toxicity is reduced.

The present invention relates to compounds of Formula (I)wherein Ar1, A, R1 and R2 are as described in the description, their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of Formula (I), and especially to their use as Galectin-3 inhibitors.

The invention relates to the technical field of analysis and detection, and discloses a method for separating and detecting flavonoid components in chrysanthemum, which comprises the following steps: extracting a chrysanthemum sample to be detected by using a methanol aqueous solution to obtain an extracting solution; octadecylsilane chemically bonded silica is adopted as a chromatographic column filler, high performance liquid chromatography detection is performed on the extracting solution according to a specific elution procedure, and a chromatogram is obtained; and performing qualitative and / or quantitative analysis on the flavonoid components in the chrysanthemum sample to be detected according to the chromatogram. The method is used; according to the present invention, a variety of flavonoid components such as chlorogenic acid luteolin-7-O-beta-D-glucoside, quercetin-3-O-B-D-galactoside, isochlorogenic acid B, kaempferol-3-O-rutinoside, isochlorogenic acid A, isochlorogenic acid C, diosmetin-7-O-B-D-glucoside, luteolin and apigenin can be effectively separated from chrysanthemum, synchronous detection of the components is realized, interference of other components in the chrysanthemum can be prevented, and the method has relatively high detection accuracy.

The invention discloses naked hydroxyl urolithin A 8 O galactoside and its synthesis method and application, and belongs to the field of organic synthesis technology. The synthesis method of the urolithin A 8 O galactoside comprises the following steps: 3 hydroxy 6 bromo benzaldehyde reacts with benzyl bromide, and the product is oxidized by hydrogen peroxide and then coupled with resorcinol to obtain naked hydroxyl urolithin A; galactose is successively replaced by acetic anhydride and hydrogen bromide to obtain brominated galactose pentaacetate; naked hydroxyl urolithin A undergoes oxygen glycosidation reaction with brominated galactose pentaacetate, and the product removes the hydroxy protecting group to obtain naked hydroxyl urolithin A 8 O galactoside. The present invention is beneficial in that: the problem that urolithin A is insoluble in water is solved, and the product has good hypoglycemic and hypolipidemic abilities; the process route is rationally designed, easy to operate, and the basic raw materials used are low in cost and suitable for industrial production.

The present invention provides a high-reflectivity single-crystal silicon alkali polishing additive, an alkali polishing liquid, a preparation method, and uses. The high-reflectivity single-crystal silicon alkali polishing additive comprises the following components in parts by mass: 1-2 parts of a protective agent; 1-5 parts of a polishing agent; 0.1-1 parts of a surfactant; 0.5-2 parts of a corrosion inhibitor; and 60-80 parts of deionized water. The protective agent is a silyl ether compound; the polishing agent is a lithium-containing compound; the surfactant is one or more of dodecyl glucoside, decyl glucoside, pyranose glucoside, and o-nitrophenyl-β-D-pyranose galactoside; and the corrosion inhibitor is one or more of polyglutamic acid, polylysine, m-hydroxybenzoic acid, and p-hydroxybenzoic acid. The alkali polishing liquid to which the alkali polishing additive is added can improve the polishing effect of silicon wafers, achieve highly selective corrosion, and ultimately obtain single-crystal silicon wafers with a highly reflective back-polished surface, thereby improving the conversion efficiency of solar cells.