67 results about "Galactosides" patented technology

Adjuvant combinations comprising at least one NKT activator, such as alpha-galactosylceramide (α-Gal-Cer) or iGb3, a CD40 agonist and optionally an antigen are disclosed. The use of these immune adjuvants for treatment of various chronic diseases such as cancers is also provided.

The invention relates to extractive of chickweed flavone glycoside, containing apigenin-6-C-Beta-D-galactose-8-C-Alpha-L-arabinoside and apigenin-6-C-Alpha-L-arabinoside-8-C-Beta-D-galactoside. The invention also relates to the extraction method of the chickweed flavone glycoside extraction, the drug compound containing the extractive and the purpose for preparing lipid lowering drug.

Compositions and methods are described in which a primary detergent or surfactant in an aqueous solution is removed by the addition of a secondary detergent or surfactant in concentrations that exceed the critical micellar concentration (CMC) of the secondary detergent or surfactant. These compositions and methods are particularly applicable to protein-containing solutions. Typical primary detergents / surfactants include polysorbate 20, polysorbate 80, and Triton X-100. Suitable secondary detergents or surfactants can be ionic, nonionic, or zwitterionic. Typical secondary detergents / surfactants include, but are not limited to, galactoside detergents (e.g. octyl-β-galactoside), glucamide detergents (e.g. MEGA 8, MEGA 9, MEGA 10), cholamide detergents (e.g. CHAPS, CHAPSO, BIGCHAPS), and sulfobetaine detergents (such as sulfobetaine 3-10).

The invention discloses an application of cornflower-3-O-galactoside in preparing foods or medicines for improving cognitive functions of old people. Results from animal experiments show that: compared with a control group (mice are fed with distilled water), the step-through latencies of animals fed with the cornflower-3-O-galactoside are all evidently prolonged; the escape latencies of mice in Morris water maze are evidently shortened; the duration time on a platform quadrant is evidently prolonged, and times of crossing the platform are evidently increased. The hint shows that the spatial memory ability of the old-aged mice compensated with the cornflower-3-O-galactoside can be evidently improved. Compared with an H2O2 model group, the LDH activity of hippocampal nerve cell supernate in the group fed with the cornflower-3-O-galactoside evidently decreases and the nerve cells apoptosis rate evidently decreases. The hint shows that the cornflower-3-O-galactoside can evidently suppress the hippocampal nerve cell apoptosis induced by H2O2 and play a protection role in the hippocampal nerve cells damaged by H2O2.

The invention discloses a detecting kit capable of fast, simply and simultaneously detecting 6 aquatic product pathogenic bacteria such as the pseudomonas aeruginosa and the like. The kit comprises an oxidase test paper, a hydrogen sulfide culture medium, a halophilic identifying reagent, an ortho-nitrophenol beta-D-galactoside culture medium, a pectinose culture medium, a lactobiose culture medium, saccharose culture medium, a glucose culture medium, a mannose culture medium, a cellobiose culture medium, a dextrose oxidation and fermentation identifying reagent, an arginine bi-hydrolytic enzyme identifying reagent, an ornithine identifying reagent, a lysine identifying reagent, an amino acid decarboxylation identifying reagent and an indol identifying reagent. The kit has simple reagent composition and preparation method and use method, has low cost, does not need expensive apparatuses and operators with mature technology, compared with a bacterium fast automatic identifying system and a detecting technology based on the nucleic acid. The detecting kit is suitable for initially detecting the normal pathogenic bacteria of aquatic animals, is particularly suitable for the use of aquatic product popularization staff at the production line, and immediately excludes the difficulty and the anxiety for fishing peasants.

The invention discloses application of delphinin 3-[2-(xyloside)galactoside] as active ingredient to preparation of lipid-lowering drugs, and provides application of delphinin 3-[2-(xyloside)galactoside] and cyaniding-3-O-glucoside as active ingredients to preparation of lipid-lowering drugs. According to the application, delphinin 3-[2-(xyloside)galactoside] is sinly adopted or delphinin 3-[2-(xyloside)galactoside] and cyaniding-3-O-glucoside are reasonably matched to obtain two active ingredients for a synergistic effect, and animal experiments prove that application is capable of significantly reducing the blood lipid levels in mice, thereby providing a new pharmaceutical composition for lipid lowering for people.

The invention belongs to the field of medicinal chemistry, and particularly relates to a new use and preparation method of a compound, namely the new use and preparation method of (3beta,5alpha,22alpha,25R)-spirosolane-3-O-beta-D-glucopyranosyl-(1->2)-O-[beta-D-xylopyranose-(1->3)]-O-beta-D-glucopyranosyl-(1->4)-beta-D-pyran galactoside; the compound can inhibit lung cancer cells, makes the growth period of the lung cancer cells arrested in the early stage and promotes apoptosis of the lung cancer cells. Therefore, the compound can be used in preparation of anticancer drugs, especially in preparation of anti-lung cancer drugs.

The invention discloses an alkyl 2,3,4,6-tetra-O-acetyl-beta-D-pyran galactosyl-(1->4)-2,3-di-O-acetyl-beta-D-pyran heteroside and a preparation method thereof. The raw material lactose is completely acetylized to react with alcohol to obtain alkyl-O-hepta-acetyl galactoside, and 6-acetyl on glucose group is selectively deacetylated to obtain the target compound. The synthesizing method provided in the invention has the advantages of simple, convenient and fast operation, low cost and the like. The invention also discloses an application of alkyl galactoside receptor in fast synthesizing non-natural oligosaccharide having antitumor activity.

The invention provides a method for preparing a probiotic additive for a yellow wine lees feed. The multi-functional probiotic additive for the yellow wine lees feed is prepared by compounding multiple probiotic strains, namely Clostridium butyricum, Lactobacillus fermentum ML7, Lactobacillus fermentum La-YI, and Bifidobacterium animalis subsp. lactis Qq08. The additive can regulate intestinal floras of animals and recover intestinal flora disturbance caused by antibiotics, has the functions of reducing emergency and heat-sensitive reactions, effectively degrades nutritional antagonists with heavy components such as alpha-galactosides and the like in cake feeds, remarkably improves feed conversion ratio, has the effect of degrading cholesterol, reduces the absorption of the cholesterol inintestines, and reduces the content of the cholesterol in animal products; and the additive can improve the palatability of the yellow wine lees feed, and increase the appetite of livestock so as to increase the feed intake.