8 results about "Growth stimulation" patented technology

A transport device for increasing biological activity within a patient includes a base including a first end, a second end, an upper surface located between the first end and the second end, and a lower surface located between the first end and the second end, a base anchor configured to statically couple the base to a first portion of a bone of a subject, a translatable anchor configured to engage a growth stimulator, a leadscrew dynamically coupling the base to the translatable anchor, wherein the leadscrew is configured to rotate about a leadscrew axis while substantially maintaining its longitudinal position along the leadscrew axis in relation to the base, such that the growth stimulator, when engaged with the translatable anchor, is capable of independent movement in relation to the base along a stimulation axis that includes at least some transverse displacement with respect to the bone when the base is coupled to the bone via the base anchor, and a screw drive rotatably coupled to the leadscrew and configured to couple to a rotatable mating tool that is configured to rotate the leadscrew via the screw drive.

The present disclosure relates to a kit for detecting a soluble growth stimulation expressed gene 2 protein. In particular, the present disclosure relates to a latex-enhanced turbidimetric immunoassay kit for detecting the concentration and / or content of the sST2 in human samples. The kit can be used in transmission immunoturbidimetry and scattering immunoturbidimetry. The kit comprises a buffer system, an anti-interference component, latex microspheres, an anti-sST2 antibody, etc. The latex-enhanced immunoturbidimetric agent of the present disclosure can detect sST2 proteins within a range of <400 ng / ml in a sample, with a sensitivity of up to 0.1 ng / ml and a high specificity, accuracy and precision. The kit is suitable for a fully automatic biochemical analyzer and a scattering analyzer, and has the advantages of convenient and fast use and low cost, and can be used clinically to detect the sST2 protein.

The application provides a molybdenum-rhenium alloy bone plate system with a growth stimulating function, and belongs to the technical field of trauma surgery instruments. The bone growth stimulating mechanism is arranged on one side of the bone plate body facing the bone surface through the micro self-adaptive lifting mechanism, and the pressure value between the bone growth stimulating mechanism and the bone surface is automatically adjusted by the control module, so that the electrode unit of the bone growth stimulating mechanism can be stably attached to the trauma surface without affecting the blood supply, the trauma bone surface is continuously and stably stimulated by direct current, the activity of osteoblast proliferation is promoted, and bone healing is accelerated.

The present invention relates to a combination of a CNP agonist and at least one further biologically active moiety or drug for use in a method for the treatment or prevention of disorders that benefit from growth stimulation, pharmaceutical compositions comprising at least one CNP agonist, preferably a controlled-release CNP agonist, wherein the pharmaceutical composition comprises at least one further biologically active moiety or drug, to the use of these pharmaceutical compositions as medicaments, to their use in the treatment of disorders that benefit from growth stimulation and to methods of preventing or treating a patient having a disorder that benefits from growth stimulation.

A system for increasing biological activity within a patient includes a housing, a drive carried within the housing, an indexing contour carried by the housing and configured to substantially stabilize the housing in relation to a transport device base of a transport device configured to move a growth stimulator in relation to a bone of a subject, a locking portion configured to releasably lock the housing to the transport device base, a rotatable mating tool carried by the housing, wherein the drive is configured to cause the rotatable mating tool to rotate, and wherein the rotatable mating tool is configured to be rotationally coupled to a screw drive of a leadscrew of the transport device when the housing is stabilized with the transport device base via the indexing contour and is locked to the transport device base via the locking portion, and a control unit configured to output a control signal configured to direct the drive to rotate the rotatable mating tool.

An interspinous fusion device is described. It includes a first member with a column of teeth, and a second member with a column of recesses adapted to mate with the column of teeth of the first member. The first member and the second member have opposing windows on their walls, such that when the first member is mated with the second member an unobstructed passage is formed through the opposing windows. The first member and the second member lock together when the teeth and recesses are mated, said locking occurring without the aid of a set screw, pin or other mechanical component.

In order to provide a new agent for actively controlling hair growth in subjects, the present invention suggests an active agent for use in hair growth regulation, particularly for use in the treatment of hair growth (stimulation or inhibition), wherein said active agent activates, enhances, inactivates, blocks or dampens the cellular response of the olfactory receptor OR10J1 or interferes with the expression of said receptor. Furthermore, the present invention is directed to compositions for use as a cosmetic or medicament or food supplement in the treatment of hair growth said composition comprising at least one of the aforementioned active agents and at least one auxiliary agent. In addition, a non-therapeutic method of hair growth regulation is disclosed, wherein an effective amount of at least one of the aforementioned active agents is administered to a subject.

The present disclosure relates to a kit for detecting a soluble growth stimulation expressed gene 2 protein. In particular, the present disclosure relates to a latex-enhanced turbidimetric immunoassay kit for detecting the concentration and / or content of the sST2 in human samples. The kit can be used in transmission immunoturbidimetry and scattering immunoturbidimetry. The kit comprises a buffer system, an anti-interference component, latex microspheres, an anti-sST2 antibody, etc. The latex-enhanced immunoturbidimetric agent of the present disclosure can detect sST2 proteins within a range of <400 ng / ml in a sample, with a sensitivity of up to 0.1 ng / ml and a high specificity, accuracy and precision. The kit is suitable for a fully automatic biochemical analyzer and a scattering analyzer, and has the advantages of convenient and fast use and low cost, and can be used clinically to detect the sST2 protein.