3 results about "Iodophenol" patented technology

This invention discloses a substrate solution formulation and preparation method for the Antu A2000 fully automated chemiluminescence immunoassay analyzer, belonging to the field of in vitro diagnostic reagent technology. The substrate solution includes solution A and solution B, wherein solution A consists of hydrogen peroxide, a buffer, and a hydrogen peroxide stabilizer; solution B consists of purified luminol, a luminescence enhancer, and a buffer. The hydrogen peroxide stabilizer is selected from HEDP, 8-hydroxyquinoline, urea, or sodium polyacrylate; the luminescence enhancer is selected from 4-morpholinopyridine, p-iodophenol, or imidazole; luminol is purified by ethanol-water gradient recrystallization and ether extraction. The preparation method includes: weighing and dissolving the components, adjusting the pH, stirring and filtering, and dispensing into opaque containers. This invention uses a stabilizer to improve the stability of hydrogen peroxide, an enhancer to increase the luminescence intensity, and reduces impurity interference, resulting in high sensitivity and low cost. It can completely replace the original reagents, exhibiting significant economic and social benefits.

The invention discloses preparation and stabilization methods of an INO3 solution and application of the INO3 solution. The preparation method comprises the following steps: dissolving silver nitrate in a first organic solvent to form a silver nitrate solution; dissolving an iodine elementary substance in a second organic solvent to form an iodine elementary substance solution; mixing the silver nitrate solution with an iodine simple substance solution, and carrying out a reaction according to a reaction equation AgNO3 + I2-AgI + INO3; and separating AgI precipitate generated by the reaction to obtain an INO3 solution. When a non-acetonitrile solvent is used, acetonitrile needs to be added as a stabilizer, so that the volume content of acetonitrile in the final solution is greater than or equal to 50%. The INO3 solution can be used as a bifunctional reagent for synchronous iodination and nitration reactions of aromatic compounds. The half-life period of the INO3 solution prepared by the method provided by the invention in an acetonitrile system under the dark condition of 25 DEG C reaches 48.5 days, the product stability is good, the INO3 solution has excellent activity on the bifunctionalization reaction of aromatic compounds such as phenol, and nitrophenol and iodo-phenol products can be generated at the same time.

This invention discloses an axially chiral bipyridine ligand, its preparation method, and its uses. The axially chiral bipyridine ligand has the structure of general formula (Ⅰ): the axially chiral bipyridine ligand contains a binaphthalene structure, wherein part A is selected from A-1, A-2, or A-3; part B is a hydrogen atom or is the same as part A. The complex catalyst formed in situ in the reaction system of the axially chiral bipyridine ligand and copper salt in this invention exhibits high catalytic activity, good to excellent enantioselectivity, and good substrate universality in the asymmetric ring-opening iodination, thioesterification, and hydrolysis of cyclic diaryliodonium salts to synthesize highly optically pure, diverse substituted 1,1'-bi-2-iodobenzene compounds, 1,1'-bi-2'-iodo-2-thioester compounds, and 1,1'-bi-2'-iodo-2-phenol compounds, respectively, showing great promise for industrial applications. This invention belongs to the field of asymmetric synthetic chemistry.