83 results about "Metal Chelating Agents" patented technology

Laundry additive compositions that include a metal sequestration agent and that may be characterized by an acidic pH. Related methods of treating a fabric, for example with a wash liquor and a rinse liquor, with such compositions and / or agents. Uses of such laundry additive compositions.

The invention belongs to the field of daily chemicals, and particularly relates to a body cleaning composition containing folium artemisiae argyi extract and a preparation method of the body cleaning composition. 14%-20% of a surfactant; 0.5-5% of a skin conditioner; 0.01%-0.1% of a metal chelating agent; 0.01%-1.2% of a preservative; 0.01%-1% of a pH regulator; 1 to 1.5 percent of flavoring agent; 0.01%-1% of a viscosity modifier; and the balance of deionized water. The plant functional composition comprises a folium artemisiae argyi extract and a rosa canina fruit extract. The folium artemisiae argyi extract and the rosa canina fruit extract in the composition can achieve a synergistic effect, free radicals can be effectively removed, release of cell factors and inflammatory mediators can be inhibited, and the composition has anti-inflammatory and soothing effects, can relieve uncomfortable symptoms such as skin redness and itching and has a certain whitening effect.

The invention discloses an inflorescence gene silencing method which comprises the following steps: firstly, synthesizing a specific nucleotide fragment according to a target gene, and constructing the specific nucleotide fragment to a plant virus vector; introducing the constructed plant virus vector and the corresponding helper plasmid into the inflorescence; soaking the inflorescence in a metal chelating agent salt solution; and finally, screening to obtain plants with inflorescences subjected to target gene silencing. The chrysanthemum capitulum is selected as an infection object, the silencing method is optimized, the target gene silencing efficiency is remarkably improved, the phenotype detection period after infection is remarkably shortened, and the method is efficient, convenient and high in operability. Meanwhile, the method can effectively avoid the cross protection phenomenon of plants, overcomes the obstacle of limited transmission range of viral vectors, does not need to consider the problems of death and growth cycle of tissue culture seedlings or seedlings after infection, and provides a feasible means for rapid identification of chrysanthemum gene functions and large-scale development of chrysanthemum gene function research.

The application discloses a preparation method of a thermal gradient self-adaptive hybrid modified retarder, and the method comprises the following steps: dissolving a metal chelating agent monomer and a hydroxide into water and stirring to obtain a first solution; adding an organic small molecule into the first solution to react and obtain a second solution; adding a reaction agent dropwise into the second solution to react and obtain a third solution; and filtering the third solution to obtain the retarder. The thickening time of the cement slurry added with the retarder can meet the construction requirements of high temperature and high pressure, and the cement slurry still has good early strength and other characteristics under the condition of lower temperature, so that the purpose of temperature self-adaptation is achieved, and the construction safety and quality of the ultra-deep well cementing are ensured.

A method for inhibiting or preventing polymerization of a polymerization composition comprises: adding at least one inhibitor(s) to the polymerization composition to stabilize and inhibit the polymerization of the polymerization composition, wherein the polymerization composition contains disilacyclobutane monomers, wherein the inhibitor is selected from amine compounds, quaternary ammonium salts or metal chelating agents.

Disclosed herein is method for conjugating a metal chelating agent to a functionalized dextran by reacting a chelator with an aminated dextran backbone, where the chelator comprises a one, and only one, derivatized carboxylic acid group to form a chelator-dextran complex. In certain aspects, the dextran-chelator complex is substantially free of intra- or intermolecular crosslinking. In certain aspects, the functionalized dextran is an amine dextran, an alkynyl dextran, or a thiol dextran. In exemplary implementations, the functionalized dextran is an amine dextran. In further embodiments, one and only one carboxylic acid group on the chelating agent is derivatized as a N-hydroxysuccinimide (NHS) ester.

The invention relates to a cleaning agent and a preparation method thereof, the cleaning agent comprises bioactive hydrolase, polyol, a metal chelating agent, an alkaline pH regulator, a nonionic surfactant and water, and the polyol contains at least four hydroxyl groups. A dense hydrogen bond network and a space wrapping effect are formed by a polyhydroxy structure of polyhydric alcohol and enzyme molecules, so that the stability of enzyme in an alkaline environment and a high-temperature condition is remarkably improved, and the applicable temperature and pH range of the cleaning agent is greatly widened due to the characteristic; the problem that the use condition of a traditional enzymatic cleaning agent is limited due to the fact that enzyme is prone to inactivation is solved.

A method and gel buffer for capillary electrophoresis (CE) separation of proteins. The gel buffer solution comprises a buffer component, a hydrophilic polymer, an organic additive, a detergent and a metal chelating agent. By adopting a gel buffer solution, the separation degree of a main peak and an acromion can be improved when protein is separated by capillary electrophoresis (CE).

The invention belongs to the technical field of refined cotton production processes, and particularly relates to a cooking aid for controlling cotton linter cooking polymerization reduction and a production process. The cooking auxiliary agent is prepared from the following components in percentage by mass: 0.35%-1.1% of magnesium chloride, 61.2%-87.7% of a reducing agent and 11.8%-37.7% of a metal chelating agent, totaling 100%. By means of the synergistic effect of the cooking auxiliaries, disordered degradation of cellulose can be effectively blocked in the cotton linter cooking process, the polymerization degree of alkalized cotton is greatly improved, and the polymerization degree can stably reach 3,250 DP or above; the purpose of removing impurities can be achieved; therefore, a guarantee can be provided for obtaining refined cotton with qualified impurity indexes and higher polymerization degree.

The invention discloses an HRP chemiluminescent substrate system, a kit and a preparation method, the HRP chemiluminescent substrate system is composed of a liquid A and a liquid B which are physically isolated and stored; the solution A is an alkaline buffer system with the pH value of 9.0-9.6, and comprises isoluminol or a salt substrate thereof, a cationic surface active agent CTAC and a metal chelating agent diethylene triamine pentaacetic acid; and the solution B is an acidic solution with the pH value of 4.5-5.5, and comprises an oxidizing agent and a reinforcing agent N-(3-chloro-4-hydroxyphenyl) acetanilide. According to the invention, the reinforcing agent N-(3-chloro-4-hydroxyphenyl) acetanilide is placed in the acidic liquid B, when the acidic liquid B is mixed with the alkaline liquid A, the mixed system is maintained at a specific pH value of 8.3-8.6, and the reinforcing agent is rapidly dissociated into phenoxy anions; and carrying out in-situ capture and enrichment on a micelle interface by CTAC cationic micelles with positive charges, which exist in the solution A in advance, through electrostatic attraction. And in cooperation with a low-ion-strength environment brought by no buffer salt in the liquid B, the system ensures the high activity of the HRP enzyme, realizes directional interface catalysis of the enhancer, and significantly improves the luminous efficiency and stability.

The application discloses a heavy metal chelating agent and a preparation method thereof. The heavy metal chelating agent is obtained by controlling the synthesis of melamine formaldehyde resin prepolymer and introducing a dithiocarbamate salt group with a chelating function into the structure of the melamine formaldehyde resin prepolymer. The heavy metal chelating agent has the characteristics of high efficiency and stability, high heavy metal removal rate, fast settling speed of chelation products, low leaching, and low cost, and is suitable for industrialized treatment of heavy metal pollution in fly ash and industrial wastewater.

A polymer breaking solution usable in fracking and other downhole applications comprises a solution of aqueous hydrogen peroxide, an anionic surfactant, a metal chelating agent, an acidic pH buffer, a soluble zinc compound, and in some embodiments, a viscosifying agent. In other embodiments, the solution may additionally comprise a linear hydrophobic surfactant. At treatment concentrations of between 500 ppm to 1,500 ppm, the solution is non-toxic and usable at a wide range of downhole temperatures (32° C. to 82° C.).

The present invention provides a cleaning agent composition for hard surfaces that exhibits excellent sustained effectiveness in suppressing the occurrence of urine scale stains and yellow stains derived from urine on hard surfaces, and a method for cleaning hard surfaces using the same. [Solution] A cleaning agent composition for hard surfaces, comprising the following components (a), (b), (c), and water, wherein the mass ratio (c) / [(a)+(b)] of the content of component (c) to the total content of components (a) and (b) is 0.005 or more and 0.3 or less. (a) Ingredients: Metal chelating agent (b) Component: Foaming surfactant (c) Component: Water-soluble polymer

The invention relates to the technical field of soil heavy metal remediation, in particular to a humic acid slow-release fertilizer for improving the remediation efficiency of barbadosnut on cadmium-contaminated soil and a preparation method of the humic acid slow-release fertilizer. The fertilizer specifically comprises the following components: polyvinyl alcohol, span 80, urea, calcium hydrophosphate, potassium sulfate, magnesium oxide, humic acid, DA-6, IAA, IBA, EGTA, corn straw compost and the like. The humic acid slow-release fertilizer and the application method thereof, provided by the invention, have remarkable beneficial effects in the aspect of improving the remediation efficiency of the barbadosnut on the cadmium-polluted soil. According to the slow-release fertilizer, humic acid, plant hormones, a metal chelating agent and nutrient elements are scientifically proportioned, and corn straw compost is combined as an organic carrier, so that slow release and efficient utilization of nutrients are realized. The high-activity extraction process of humic acid ensures the strong complexing ability of rich functional groups and heavy metals, and significantly enhances the cadmium absorption and transport ability of jatropha curcas.

The invention discloses an experimental kit for chloroplast pigment extraction and separation and application, and belongs to the technical field of photosynthetic pigment extraction and separation, a surfactant and EDTA sodium are added during extraction, and an efficient aluminum foil silica gel thin layer and a composite chromatographic solution are adopted during separation; the chromatography medium is an efficient silica gel thin layer. In the process of extracting and separating the photosynthetic pigment, a surfactant and an EDTA (Ethylene Diamine Tetraacetic Acid) sodium metal chelating agent are added, the ratio of a chromatography medium to a chromatography liquid is optimized, a filtering and chromatography device is simplified, the extraction rate and the separation degree of the pigment are remarkably improved, the operation is simpler and safer, and finally 6-8 kinds of the photosynthetic pigment can be separated from fresh spinach leaves. 13 chloroplast pigments are separated from the leaf dry powder.

The application discloses a substation oil-filled equipment live extinguishing medium, and the mass concentration ratio of raw materials of the extinguishing medium is as follows: 5-35% of ethylene glycol, 5-20% of non-ionic foaming emulsifier, 3-8% of ethylene glycol butyl ether, 2-5% of non-ionic film-forming spreading agent, 0.2-0.6% of xanthan gum, 0.15-0.5% of non-ionic organic corrosion inhibitor and 0.5-1.5% of metal chelating agent, and the rest is deionized water with conductivity lower than 10 mu s / cm. The product formula uses non-ionic raw materials, and after being mixed with water in a proportion, the conductivity is lower than 200 mu s / cm. The conductivity of the extinguishing agent is prevented from being improved under long-term storage by adding a corrosion inhibitor / chelating agent compound, and the extinguishing agent can be used in combination with a water quality monitoring and processing device to realize spraying and extinguishing for live equipment within the effective period of the extinguishing agent. The extinguishing medium uses a new type of fluorosilicon / fluoroether structure film-forming agent, which can be naturally degraded in the environment on the basis of ensuring hydrophobicity, oleophobicity, film forming and spreading. Meanwhile, by adding a new type of high-efficiency cooling and emulsifying aid, the ability of the product to quickly extinguish and prevent re-ignition is ensured.

The present invention relates to a conjugate for use in the treatment of cancer, the conjugate comprising a first moiety A selected from metal chelating agents, a second moiety B selected from lysosomotropic agents; and a linker L that binds moieties A and B together. The invention also relates to their use in the pharmaceutical field, in particular in a method for the treatment of cancer.

The invention discloses a rapidly crystallized anti-aging polylactic acid composition as well as a preparation method and application thereof. The rapidly crystallized anti-aging polylactic acid composition comprises the following components: 70-95 parts of poly-L-lactic acid; 5 to 20 parts of multi-arm D-polylactic acid; 0.1 to 5 parts of acetylated cellulose nanocrystal; 0.05-1 part of a metal chelating agent; the multi-arm dextro polylactic acid is prepared by initiating ring opening polymerization of D-lactide by a polyol initiator, and the polyol initiator is selected from two or more of glycerol, 1, 1, 1-trimethylolpropane, pentaerythritol, erythritol, dipentaerythritol and sorbitol. The metal chelating agent is used for inhibiting hydrolysis of ester bonds, formation of stereocrystals is promoted under the action of the nucleating agent through the multi-arm right-handed polylactic acid of a branched structure, high transparency and heat resistance are obtained, and a blister product prepared from the composition has the advantages of being transparent, resistant to heat, rapid in demolding, stable in size and the like.

The invention belongs to the technical field of inhalation preparations and pulmonary drug delivery, and particularly relates to an atomization preparation for vitamin K inhalation drug delivery and preparation and application thereof. According to the preparation, dipalmitoyl phosphatidylcholine, cholesterol and optional anionic phospholipid are adopted to construct a bionic lung surface activity liposome skeleton LA1, an MK-7 organic phase is intercalated into a liposome double-layer hydrophobic area under the condition of controlling temperature and an energy path, and a continuous phase containing sodium chloride, propylene glycol and a pH regulator is matched to form an isotonic near-neutral environment; a neutral oil phase, a fat-soluble antioxidant, an optional metal chelating agent and a viscosity modifier can be introduced to synergistically optimize the atomization performance. The apparent viscosity of the prepared atomization preparation at 25 DEG C is 1.0-2.5 mPa.s, the osmotic pressure is 280-320 mOsm / kg, the average particle size of lipidosome Z is 80-150 nm, the PDI is not larger than 0.25, the mass median diameter of fog drops atomized by a vibration net type atomizer is 2.0-3.0 microns, the fine particle fraction is not smaller than 60%, and the MK-7 content retention rate is not lower than 90% after 6 months of accelerated storage at 25-40 DEG C.

The application discloses a preparation method of a heavy metal chelating agent composite material, and the method comprises the following steps: S1, montmorillonite is placed in a dilute acid solution for treatment, and then the montmorillonite is washed, dried, crushed, and ground to obtain montmorillonite powder; S2, polyvinyl acetate is dissolved in a solvent to obtain a blending liquid, the montmorillonite powder is added and stirred uniformly, then ionic monomers and an initiator are added and continuously stirred, and then polyvinylpyrrolidone is added and stirred uniformly; after the stirring is completed, the blending liquid is left to stand, and then the blending liquid is filtered; the obtained product is washed and dried to obtain a modified montmorillonite copolymer composite; S3, the modified montmorillonite is placed in a urea solution for heat treatment, and then the modified montmorillonite is filtered; the obtained product is sequentially washed, freeze-dried, and sieved to obtain the heavy metal chelating agent composite material. The chelating agent composite material can effectively remove heavy metal ions in polluted water.

The invention relates to a nadifloxacin emulsifiable paste and a preparation method thereof, the nadifloxacin emulsifiable paste comprises an active component nadifloxacin and pharmaceutic adjuvants, and is a water-in-oil or oil-in-water external emulsifiable paste preparation. The chemical and physical stability of the product is remarkably improved by adopting a buffer type alkaline hydrotropy system formed by sodium hydroxide and diethanol amine in a synergistic manner, an edetate disodium metal chelating agent and a specifically-formed composite oil phase matrix and combining a vacuum emulsification and double homogenization process; and the preparation process parameters are clear, the industrial amplification can be realized, and the technical problems of poor stability, large quality fluctuation, limited curative effect and the like of the existing nadifloxacin external preparation are solved.

The invention provides a composite admixture for red mud-based filling paste, which comprises the following components in percentage by mass: 35-55% of an acid-base regulator which comprises phosphate, organic acid and neutral salt; 30-45% of a rheology modifier, wherein the rheology modifier comprises a water reducing agent, a retarder and an air entraining agent; and 10-25% of a metal anti-leaching agent, wherein the metal anti-leaching agent comprises a metal chelating agent and a waterproof agent. The composite additive is used in the red-mud-based filling paste, the flowing property of the paste can be improved, the compressive strength of the red-mud-based paste can be improved, leaching of metal ions such as aluminum and sodium is reduced, and the requirement for environmental protection is met.

The present invention addresses the problem of providing a photosensitive resin composition which, when formed into a cured film, has high transparency and chemical resistance, has low film stress, and has high adhesion to a metal layer containing molybdenum, aluminum, or nickel. In order to solve this problem, a photosensitive resin composition is provided which contains a siloxane resin having a radical-polymerizable group, a metal chelating agent, and a photo-radical polymerization initiator, and in the siloxane resin having a radical-polymerizable group, the amount of the metal chelating agent in the siloxane resin having a radical-polymerizable group is 100 mol% per 100 mol% of all organosilane units, and the amount of the photo-radical polymerization initiator in the siloxane resin having a radical-polymerizable group is 100 mol% per 100 mol% of all organosilane units. The content of an organosilane unit (D unit) represented by (R) 2SiO2 / 2 (R is an organic group) is 30 mol% or more and 85 mol% or less.

The present invention provides a reducing agent composition for iron oxide and / or iron hydroxide, and a method for reducing iron oxide and / or iron hydroxide by contacting the reducing agent composition with iron oxide and / or iron hydroxide, the reducing agent composition for iron oxide and / or iron hydroxide being a reducing agent composition containing components (A) to (C) and having a pH in the range of 7 to 11, the oxidation-reduction potential when dissolving component (A) in an aqueous solution containing components (B) and (C) becoming -600 mV or less within 20 minutes after the start of dissolving component (A), and the rate of change of the oxidation-reduction potential becoming a value of 0 mV / minute or more within 60 minutes. (A) reducing agent; (B) water-soluble metal chelating agent; (C) amine compound.

Radiopharmaceuticals and conjugates targeting GPC3, as well as their compositions and uses, are provided herein. In one embodiment, a conjugate comprising a peptide having avidity to GPC3 and a metal chelating agent configured to bind to a radionuclide is provided herein. The conjugate described herein may further comprise a linker connecting the chelating agent and the peptide. The conjugate described herein may further comprise a radionuclide. In one embodiment, a radiopharmaceutical comprising a peptide and a metal chelating agent binding to a radionuclide is provided herein. The conjugate described herein may further comprise a linker connecting the chelating agent and the peptide. Methods for treating cancer by administering the radiopharmaceuticals, conjugates, and compositions thereof are further provided herein.

The invention relates to the field of biological detection, in particular to a nucleic acid releasing agent and a preparation method and application thereof. The invention provides a nucleic acid releasing agent. The nucleic acid releasing agent comprises chaotropic salt, polyethylene glycol, a surfactant, an antifreeze agent, a penetrant, a metal chelating agent, an antioxidant and a buffer solution. According to the invention, the extraction-free rapid nucleic acid releasing agent is researched and developed, and an ultrasonic treatment scheme is introduced to carry out rapid pretreatment on the sample, so that the problems of tedious nucleic acid extraction process, long time consumption and low efficiency in the prior art are successfully solved, and an efficient, convenient and low-cost nucleic acid releasing and detecting scheme is provided for clinical detection and scientific research.

The invention relates to a salt-spray-resistant single-component silicone structural sealant and a preparation method thereof. The anti-corrosion silicone sealant is prepared from the following components in parts by weight: 100 parts of alpha, omega-dihydroxy polydimethylsiloxane, 35 to 60 parts of silane coupling agent modified nano active calcium carbonate, 3 to 8 parts of a cross-linking agent, 1 to 3 parts of an adhesion promoter, 0.05 to 0.3 part of a catalyst and 5 to 15 parts of silane coupling agent modified modified anti-corrosion filler, the adhesion promoter comprises amino silane and a composite metal chelating agent, and the mass ratio of the amino silane to the composite metal chelating agent is 1: (0.2-0.5). The invention aims to provide the salt-fog-resistant single-component silicone structural sealant and the preparation method thereof, so as to solve the technical problems that a material is exposed in a high-humidity salt-fog environment for a long time, chloride ions have strong permeability, can longitudinally permeate along a microscopic channel and destroy colloid, so that the colloid is hardened and cracked, and finally a bonding interface loses efficacy.

The invention relates to the technical field of industrial cleaning agents, and provides an extremely pure solvent type cleaning agent and a nitrogen sealing preparation process, and the cleaning agent is composed of an isoparaffin solvent, a metal chelating agent, a fluorocarbon surfactant, a photocatalyst, a metallic soap lubricant, an ether solvent and a terpene stabilizer according to a specific ratio. The dirt permeating and dissolving capacity is enhanced through an intermolecular synergistic effect, and micron-sized pore deep cleaning is achieved; a fluorocarbon chain and a lubricant cooperate to construct an anti-wear and anti-corrosion film, and a terpene structure blocks an oxidation chain reaction. Nitrogen protection is adopted in the whole preparation process, a gradient filtering system is combined with an eddy current steady flow nitrogen curtain and a nitrogen pre-filling packaging process to guarantee the cleanliness of the terminal, and the process stability is guaranteed through closed-loop regulation and control of parameters such as the oxygen content, the particle size and the temperature. The cleaning agent has super-strong permeability and broad-spectrum detergency, micron-sized pore pollutants can be thoroughly removed, and a zero-corrosion protective layer is formed on the metal surface; a nitrogen protection process inhibits oxidative deterioration of components, and the storage stability of the product is greatly improved.

The invention discloses an environment-friendly multi-layer lubricating ultra-fine liquid which comprises the following components in percentage by mass: 42-43% of nanoscale polyether ester and 12-13% of modified silicate are adopted to construct a multi-layer lubricating structure, and a self-repairing lubricating film is formed through intermolecular hydrogen-bond interaction; a compact passive film is formed on the surface of a workpiece by applying a gradient slow release system of organic ammonium carboxylate and a metal chelating agent, and the organic ammonium carboxylate accounts for 6%-7%, and the metal chelating agent accounts for 3.5%-4.5%; the immobilized lipase is adopted for catalytic synthesis of the special ester compound, green synthesis of key components is achieved, and Novozym435 is selected as the immobilized lipase; a sodium dihydrogen phosphate-disodium hydrogen phosphate buffer system is adopted as a pH buffer agent, and the sodium dihydrogen phosphate accounts for 1.8%-2.2%, and the disodium hydrogen phosphate accounts for 1.3%-1.7%; the lubricating oil is formed by a multi-layer lubricating structure and a compact passive film, equipment abrasion and corrosion are effectively reduced, and the service life of equipment is prolonged.

The invention discloses an application of a surfactant and / or a chelating agent in extraction of chloroplast pigments, and belongs to the technical field of photosynthetic pigment extraction. On one hand, the solubility of pigments such as beta-carotene, phaeophytin, chlorophyll a ', chlorophyll a, chlorophyll b', chlorophyll b, xanthophyll, violaxanthin and neoxanthin can be remarkably increased, and on the other hand, oxidation of ROS molecules to the pigments can be inhibited. In addition, a small amount of metal chelating agent is added into the extraction unit, so that oxidative damage of oxidizing metal ions such as Fe < 3 + >, Ag < + > and Cu < 2 + > which are possibly released from grinding equipment during extraction to pigments can be effectively inhibited.