233 results about "Metal Chelating Agents" patented technology

The invention relates to the field of metal extractant preparation, in particular to a metal extractant microcapsule and a preparation method thereof. The preparation method of the metal extraction agent microcapsule comprises the following preparation steps: (1) uniformly mixing ethyl acrylate, methacrylamide, 2-acrylamido-2-sodium methylpropanesulfonate, a cross-linking agent and an initiator, dropwise adding an emulsifier solution under a stirring condition, carrying out ultrasonic treatment, irradiating with ultraviolet light under the stirring condition for 10-20 minutes, washing with pure water, and separating to obtain a metal extraction agent microcapsule; drying to obtain a hollow microcapsule; and (2) vacuumizing the hollow microcapsule obtained in the step (1), adding a metal chelating agent, carrying out ultrasonic treatment for 5-10 hours, filtering, and washing to obtain the metal extractant microcapsule. The preparation process of the metal extractant microcapsule is simple and easy to operate, and the metal extractant microcapsule has a relatively good encapsulation efficiency on a metal chelating agent and has a relatively high removal effect on various metal ions.

The invention relates to the technical field of bamboo pulp bleaching, and particularly discloses a method for preparing all-chlorine-free bleached bamboo pulp and application. The method adopts a three-section enhanced bleaching process and comprises the following steps: firstly, decomposing lignin under an alkaline condition of 100-115 DEG C through oxygen delignification (Op section); removing transition metal ions by using sulfuric acid and a metal chelating agent with a specific structure by adopting acid pickling chelation (AQ section); and finally, deeply oxidizing the residual lignin in a high-pressure oxygen environment through oxygen enhanced bleaching (Po section). In each stage, hydrogen peroxide is used as a main bleaching agent, sodium hydroxide, sodium silicate and other assistants are matched, and ineffective decomposition of hydrogen peroxide is effectively inhibited through staged pH regulation and a metal chelation technology. The whiteness of the obtained bamboo pulp is larger than or equal to 83% ISO, the kappa number is smaller than or equal to 3.0, and the requirements of high-grade paper products are completely met.

The invention relates to the field of chelating agent preparation, in particular to an efficient metal chelating agent and a preparation method and application thereof. The preparation method comprises the following preparation steps: (1) dissolving dibutanol amine in absolute ethyl alcohol, adding carbon disulfide, reacting for 5-8 hours at 0-5 DEG C in a nitrogen atmosphere, adjusting the pH to be neutral by using a sodium hydroxide aqueous solution, and performing rotary evaporation to obtain sodium bis (4-hydroxybutyl) dithiocarbamate; and (2) adding 4-[bis (beta-chloroethyl) amino] benzaldehyde, the bis (4-hydroxybutyl) sodium dithiocarbamate obtained in the step (1) and a catalyst into absolute ethyl alcohol, heating and refluxing, reducing pressure to remove absolute ethyl alcohol, adding the obtained solid into pure water, stirring, extracting, combining organic phases, drying moisture in the organic phases, concentrating, standing for 10-20 hours, and separating to obtain the metal chelating agent. The prepared metal chelating agent has good dispersity and solubility in various solvents, and a stable metal chelate is formed through coordination chelation of active functional groups and heavy metal ions.

The invention discloses an interlayer AlN3 monatomic site anchored carbon nitride nanotube photocatalyst as well as a preparation method and application thereof, and belongs to the field of photocatalysis. The preparation method of the photocatalyst for catalyzing water and oxygen to be converted into hydrogen peroxide comprises the following steps: (1) by taking melamine, soluble aluminum salt and a metal chelating agent as raw materials, carrying out supramolecular self-assembly reaction by adopting a hydrothermal method to generate a carbon nitride nanorod precursor; and (2) roasting the carbon nitride nanorod precursor to obtain the photocatalyst. According to the photocatalyst prepared by the method disclosed by the invention, Al atoms are connected between carbon nitride layers, so that the transfer distance of carriers from the inside to the outside can be shortened, and the carrier separation efficiency is improved; the valence band position of the photocatalyst is high, and holes in the valence band have enough energy to directly oxidize water, so that the catalytic performance is greatly improved.

The invention relates to preparation and application of a tumor radiotherapy embolism microsphere preparation capable of achieving CT imaging tracing. The microsphere is prepared by taking a polyvinyl alcohol derivative as a framework material, polymerizing, cross-linking and curing the polyvinyl alcohol derivative and an N-(aminoalkyl) methacrylamide hydrochloride monomer, and further covalently connecting a metal chelating agent and a CT imaging agent 2, 3, 5-triiodobenzaldehyde. The microsphere can mark radionuclides 111ln, 68Ga, Al18F, 64Cu, 177Lu and 90Y, embolism treatment and radionuclide internal irradiation treatment are combined, meanwhile, the microsphere CT tracing function is beneficial to monitoring the distribution condition of the microsphere in real time, and ectopic embolism is reduced.

The invention discloses a preparation method of a catalyst for catalyzing directional polycondensation of acetone to synthesize mesitylene, and belongs to the technical field of catalysis. The modified active metal supported catalyst is prepared from a catalyst carrier prepared by mixing a nitrogen-doped modified carbon carrier or a composite oxide with a molecular sieve, an active metal component, a metal modification additive component and a metal chelating agent. According to the present invention, the active component is loaded on the composite modified carrier through the isovolumetric impregnation method, and the metal modification auxiliary agent component is introduced through the ion exchange method to further modify the active component, such that the requirement of the catalysis of the directional deoxidation trimerization of the acetone to prepare the mesitylene is achieved, and the catalyst prepared by the method has advantages of low price, high activity, high selectivity, good stability and the like; the problem that the separation cost is increased due to the complex equipment requirement and the separation problem of mesitylene and methyl-ethylbenzene under the similar boiling point in the traditional mesitylene production method is avoided.

Laundry additive compositions that include a metal sequestration agent and that may be characterized by an acidic pH. Related methods of treating a fabric, for example with a wash liquor and a rinse liquor, with such compositions and / or agents. Uses of such laundry additive compositions.

The inhalation suspension preparation containing the SGC receptor stimulant comprises the SGC receptor stimulant with an effective therapeutic dose or pharmaceutically acceptable salt of the SGC receptor stimulant, and pharmaceutically acceptable auxiliary materials of the suspension preparation, the pharmaceutically acceptable auxiliary materials of the suspension preparation comprise at least one of a surfactant, a pH regulator, an osmotic pressure regulator and a metal complexing agent; the inhalation suspension preparation containing the riociguat shows good lung absorption efficiency, is beneficial to reaching the same or better treatment level by reducing the administration dosage, can directly act on a diseased region through an administration route, takes effect more quickly compared with oral administration of the riociguat, and has a good application prospect. Gastrointestinal discomfort and systemic hypotension side effects caused by gastrointestinal tract contact and absorption entering a circulatory system can be avoided, the treatment cycle of an oral dosage form dosage titration administration scheme is shortened, and a better treatment scheme is provided for relieving dyspnea and syncope symptoms of pulmonary hypertension patients treated at home.

The present invention belongs to the technical field of the synthesis of industrial high-molecular adhesives, and discloses a high-temperature resistant anaerobic adhesive with a functionalized cage-shaped silsesquioxane structure, a preparation method thereof and an application. The high-temperature resistant anaerobic adhesive is composed of the following components in parts by weight: 2-40 parts of methacryloxypropyl cage-shaped silsesquioxane, 50-100 parts of methacrylate monomer, 0.1-10 parts of inhibitor, 0.1-10 parts of metal chelating agent, 1-20 parts of initiator, 0.5-10 parts of accelerator, and 1-5 parts of auxiliary material. The present invention can prepare a high-purity functionalized cage-shaped silsesquioxane, and by adding the functionalized cage-shaped silsesquioxane, the crosslinking density of the anaerobic adhesive is increased, and the heat resistance is improved, so as to synthesize a high-temperature resistant anaerobic adhesive with a functionalized cage-shaped silsesquioxane structure, and the high temperature resistance can reach 350 °C, which can meet the requirements of industry for anaerobic adhesives in high-temperature environments.

The invention belongs to the field of daily chemicals, and particularly relates to a body cleaning composition containing folium artemisiae argyi extract and a preparation method of the body cleaning composition. 14%-20% of a surfactant; 0.5-5% of a skin conditioner; 0.01%-0.1% of a metal chelating agent; 0.01%-1.2% of a preservative; 0.01%-1% of a pH regulator; 1 to 1.5 percent of flavoring agent; 0.01%-1% of a viscosity modifier; and the balance of deionized water. The plant functional composition comprises a folium artemisiae argyi extract and a rosa canina fruit extract. The folium artemisiae argyi extract and the rosa canina fruit extract in the composition can achieve a synergistic effect, free radicals can be effectively removed, release of cell factors and inflammatory mediators can be inhibited, and the composition has anti-inflammatory and soothing effects, can relieve uncomfortable symptoms such as skin redness and itching and has a certain whitening effect.

A compound comprising a prostate specific membrane antigen (PSMA)-targeting moiety of the following formula (I) or of a salt or a solvate thereof. R1 is —R1aR1b— wherein R1a is absent, —CH2—, —O—, or —S—, and R1b is —CH2— or —CHF—. R2 is —(CH2)3—O—, —(CH2)3—, —(CH2)4—, —CH2—O—(CH2)2—, or —CH2—S—(CH2)2. R3 is ethylene fused to a tricyclic fused ring. L1, L2, L3, L4, L5b L5c, L6 and L7 are linkages (e.g. peptide bonds). Xbr is a branching atom. Rrad is a radiometal chelator. Ralb is an albumin binder. n1, n2, n3, n4, and n5 are integers. When the PSMA-targeting moiety is linked to a radiolabeling group, the compound may be used as an imaging agent or therapeutic agent for PSMA-expressing diseases / conditions.

According to the decalcification-free trace DNA extraction method for the old bone sample, an independent decalcification step is not adopted, a specific metal chelating agent and a phosphoramidate derivative are introduced into a bone incubation solution, the specific metal chelating agent has high chelating capacity on calcium and magnesium ions, and the specific metal chelating agent and a complex product thereof are high in water solubility and not prone to being separated out; the phosphoramidate derivative is easy to remove and does not affect the DNA adsorption efficiency of the magnetic beads and subsequent PCR amplification, the phosphoramidate derivative preferentially acts with a phosphate group fixed site on the surface of the soil, adsorption of the soil to the DNA is greatly reduced, an incubation product can be obtained to the maximum extent, then soil impurities are removed through centrifugation, and it is ensured that no adverse effect is generated on subsequent DNA adsorption of the magnetic beads. According to the method, trace DNA can be effectively extracted and purified from old bone detection materials, independent decalcification pretreatment is not needed, sample loss is avoided, and the extracted DNA can be used for forensic medicine identification.

The invention discloses an inflorescence gene silencing method which comprises the following steps: firstly, synthesizing a specific nucleotide fragment according to a target gene, and constructing the specific nucleotide fragment to a plant virus vector; introducing the constructed plant virus vector and the corresponding helper plasmid into the inflorescence; soaking the inflorescence in a metal chelating agent salt solution; and finally, screening to obtain plants with inflorescences subjected to target gene silencing. The chrysanthemum capitulum is selected as an infection object, the silencing method is optimized, the target gene silencing efficiency is remarkably improved, the phenotype detection period after infection is remarkably shortened, and the method is efficient, convenient and high in operability. Meanwhile, the method can effectively avoid the cross protection phenomenon of plants, overcomes the obstacle of limited transmission range of viral vectors, does not need to consider the problems of death and growth cycle of tissue culture seedlings or seedlings after infection, and provides a feasible means for rapid identification of chrysanthemum gene functions and large-scale development of chrysanthemum gene function research.

The invention relates to the technical field of chemical mechanical polishing, in particular to a polishing solution and a preparation method thereof, and the polishing solution comprises the following components by weight: 600-850 parts of silica sol; 2-6 parts of a metal chelating agent; 3-7 parts of a pH regulator; 0.01 to 0.10 part of a surfactant; 1-10 parts of organic amine; 125 to 380 parts of deionized water; the surfactant is selected from at least one of fatty alcohol ether phosphate, fatty alcohol-polyoxyethylene ether, alkylphenol polyoxyethylene ether and nonylphenol polyoxyethylene ether. According to the polishing solution provided by the invention, through the synergistic effect of the surfactant and other components in the polishing solution, not only is the removal rate improved, but also a corrosion inhibition protection layer can be formed on the surface of a silicon wafer, and chemical corrosion generated on the surface of the silicon wafer due to too strong chemical action is reduced, so that the surface of the silicon wafer is prevented from being damaged; therefore, the polishing quality is improved while the removal rate is increased.

The application discloses a preparation method of a thermal gradient self-adaptive hybrid modified retarder, and the method comprises the following steps: dissolving a metal chelating agent monomer and a hydroxide into water and stirring to obtain a first solution; adding an organic small molecule into the first solution to react and obtain a second solution; adding a reaction agent dropwise into the second solution to react and obtain a third solution; and filtering the third solution to obtain the retarder. The thickening time of the cement slurry added with the retarder can meet the construction requirements of high temperature and high pressure, and the cement slurry still has good early strength and other characteristics under the condition of lower temperature, so that the purpose of temperature self-adaptation is achieved, and the construction safety and quality of the ultra-deep well cementing are ensured.

A method for inhibiting or preventing polymerization of a polymerization composition comprises: adding at least one inhibitor(s) to the polymerization composition to stabilize and inhibit the polymerization of the polymerization composition, wherein the polymerization composition contains disilacyclobutane monomers, wherein the inhibitor is selected from amine compounds, quaternary ammonium salts or metal chelating agents.

Disclosed herein is method for conjugating a metal chelating agent to a functionalized dextran by reacting a chelator with an aminated dextran backbone, where the chelator comprises a one, and only one, derivatized carboxylic acid group to form a chelator-dextran complex. In certain aspects, the dextran-chelator complex is substantially free of intra- or intermolecular crosslinking. In certain aspects, the functionalized dextran is an amine dextran, an alkynyl dextran, or a thiol dextran. In exemplary implementations, the functionalized dextran is an amine dextran. In further embodiments, one and only one carboxylic acid group on the chelating agent is derivatized as a N-hydroxysuccinimide (NHS) ester.

The present invention relates to the field of preparation of metal extractants, and particularly to a metal extractant microcapsule and a preparation method thereof. The preparation method of the metal extractant microcapsule in the present invention comprises the following preparation steps: (1) Ethyl acrylate, methacrylamide, 2-acrylamido-2-methylpropanesulfonic acid sodium salt, a crosslinking agent, and an initiator are mixed evenly, and an emulsifier solution is added dropwise under stirring conditions, followed by ultrasonic treatment. After irradiating with ultraviolet light for 10-20 min under stirring conditions, it is washed with pure water, separated, and dried to obtain hollow microcapsules; (2) The hollow microcapsules obtained in step (1) are evacuated, a metal chelating agent is added, and ultrasonic treatment is carried out for 5-10 h, followed by filtration and washing to obtain metal extractant microcapsules. The preparation process of the metal extractant microcapsule is simple and easy to operate, has a good encapsulation rate for the metal chelating agent, and has a high removal effect on various metal ions.

The application discloses a low-temperature rapid curing epoxy adhesive and a preparation method thereof. A component A is composed of an epoxy resin, a diluent and a filler, is uniformly stirred and mixed, and is vacuum degassed to obtain the component A; a component B is composed of a flow agent, a tertiary amine accelerator, a free radical scavenger, a chelating agent and a filler, the thiol, the chelating agent, the filler and the free radical scavenger are uniformly stirred, are slowly stirred and matured for at least 24 hours after passing through a three-roller machine, and then the tertiary amine accelerator is added, and the component B is vacuum degassed to obtain the component B. The thiol and the tertiary amine accelerator are used in combination, the curing speed is the fastest at room temperature, and the gel time of 60s / 25g can be achieved; the metal chelating agent and the free radical scavenger are combined to prevent the thiol from being skinned during storage, and the stable storage time is more than 6 months without skinning. The maturation of the component B enables the chelating agent to fully act on metal ions in the filler, and reduces the influence of the chelating agent on the promoting effect of the tertiary amine accelerator.

The present disclosure relates to a method of inhibiting nuclease activity in a biological sample. In accordance with certain embodiments of the present disclosure, the method comprises mixing a biological sample with a metal-chelating agent complex. The present disclosure also discloses a method of isolating a cell nucleus from a cell in a biological sample by using the metal-chelating agent complex, and a method of adding a deoxyribonucleotide to the 3'terminal of a deoxyribonucleic acid.

The invention relates to a cleaning agent and a preparation method thereof, the cleaning agent comprises bioactive hydrolase, polyol, a metal chelating agent, an alkaline pH regulator, a nonionic surfactant and water, and the polyol contains at least four hydroxyl groups. A dense hydrogen bond network and a space wrapping effect are formed by a polyhydroxy structure of polyhydric alcohol and enzyme molecules, so that the stability of enzyme in an alkaline environment and a high-temperature condition is remarkably improved, and the applicable temperature and pH range of the cleaning agent is greatly widened due to the characteristic; the problem that the use condition of a traditional enzymatic cleaning agent is limited due to the fact that enzyme is prone to inactivation is solved.

A method and gel buffer for capillary electrophoresis (CE) separation of proteins. The gel buffer solution comprises a buffer component, a hydrophilic polymer, an organic additive, a detergent and a metal chelating agent. By adopting a gel buffer solution, the separation degree of a main peak and an acromion can be improved when protein is separated by capillary electrophoresis (CE).

The invention belongs to the technical field of refined cotton production processes, and particularly relates to a cooking aid for controlling cotton linter cooking polymerization reduction and a production process. The cooking auxiliary agent is prepared from the following components in percentage by mass: 0.35%-1.1% of magnesium chloride, 61.2%-87.7% of a reducing agent and 11.8%-37.7% of a metal chelating agent, totaling 100%. By means of the synergistic effect of the cooking auxiliaries, disordered degradation of cellulose can be effectively blocked in the cotton linter cooking process, the polymerization degree of alkalized cotton is greatly improved, and the polymerization degree can stably reach 3,250 DP or above; the purpose of removing impurities can be achieved; therefore, a guarantee can be provided for obtaining refined cotton with qualified impurity indexes and higher polymerization degree.

The invention discloses an HRP chemiluminescent substrate system, a kit and a preparation method, the HRP chemiluminescent substrate system is composed of a liquid A and a liquid B which are physically isolated and stored; the solution A is an alkaline buffer system with the pH value of 9.0-9.6, and comprises isoluminol or a salt substrate thereof, a cationic surface active agent CTAC and a metal chelating agent diethylene triamine pentaacetic acid; and the solution B is an acidic solution with the pH value of 4.5-5.5, and comprises an oxidizing agent and a reinforcing agent N-(3-chloro-4-hydroxyphenyl) acetanilide. According to the invention, the reinforcing agent N-(3-chloro-4-hydroxyphenyl) acetanilide is placed in the acidic liquid B, when the acidic liquid B is mixed with the alkaline liquid A, the mixed system is maintained at a specific pH value of 8.3-8.6, and the reinforcing agent is rapidly dissociated into phenoxy anions; and carrying out in-situ capture and enrichment on a micelle interface by CTAC cationic micelles with positive charges, which exist in the solution A in advance, through electrostatic attraction. And in cooperation with a low-ion-strength environment brought by no buffer salt in the liquid B, the system ensures the high activity of the HRP enzyme, realizes directional interface catalysis of the enhancer, and significantly improves the luminous efficiency and stability.

The invention discloses a hydrogen-embrittlement-resistant precise mask plate electrolytic cleaning agent for an OLED (Organic Light Emitting Diode) and a preparation method thereof, and the hydrogen-embrittlement-resistant precise mask plate electrolytic cleaning agent comprises the following components in percentage by mass: 5-10% of KOH, 0.1-0.5% of an alkali-resistant organic metal chelating agent, 0.1-1.0% of an inorganic chelating agent, 0.01-0.2% of an ampholytic surfactant and the balance of water. According to the cleaning agent, the problem of hydrogen embrittlement in the electrolytic cleaning process of the invar alloy precise mask plate is solved in a targeted manner, and the quality and reliability of the mask plate are improved. And secondly, the added reagent has good chemical stability and environmental friendliness, and does not cause adverse effects on the subsequent processing technology and environment. In addition, the method is low in cost, and considerable economic benefits are brought to the OLED manufacturing industry.

The application discloses a heavy metal chelating agent and a preparation method thereof. The heavy metal chelating agent is obtained by controlling the synthesis of melamine formaldehyde resin prepolymer and introducing a dithiocarbamate salt group with a chelating function into the structure of the melamine formaldehyde resin prepolymer. The heavy metal chelating agent has the characteristics of high efficiency and stability, high heavy metal removal rate, fast settling speed of chelation products, low leaching, and low cost, and is suitable for industrialized treatment of heavy metal pollution in fly ash and industrial wastewater.

The invention relates to the field of cell preservation solutions, and provides a cell preservation solution, an erythrocyte simulant and a preparation method and application of the erythrocyte simulant. The cell preservation solution comprises a polyphenol compound, a buffer system, a metal chelating agent, a nutrient substance, a metabolism regulator, mannitol, poloxamer and an optional preservative. The preparation method of the red blood cell simulant comprises the following steps: taking mammal venous blood and purifying to obtain red blood cells; fixing the obtained red blood cells by using a fixing agent; and dispersing the red blood cells obtained by immobilization treatment in the cell preserving fluid provided by the invention. The cell preserving fluid is beneficial for improving the stability of red blood cells and enabling the red blood cells to maintain good uniformity; the red blood cells in the red blood cell simulant have good bottle opening stability, thermal stability and long-term stability, the variable coefficient of the red blood cells is low, and the product batch-to-batch repeatability is good.

A polymer breaking solution usable in fracking and other downhole applications comprises a solution of aqueous hydrogen peroxide, an anionic surfactant, a metal chelating agent, an acidic pH buffer, a soluble zinc compound, and in some embodiments, a viscosifying agent. In other embodiments, the solution may additionally comprise a linear hydrophobic surfactant. At treatment concentrations of between 500 ppm to 1,500 ppm, the solution is non-toxic and usable at a wide range of downhole temperatures (32° C. to 82° C.).

The present invention provides a cleaning agent composition for hard surfaces that exhibits excellent sustained effectiveness in suppressing the occurrence of urine scale stains and yellow stains derived from urine on hard surfaces, and a method for cleaning hard surfaces using the same. [Solution] A cleaning agent composition for hard surfaces, comprising the following components (a), (b), (c), and water, wherein the mass ratio (c) / [(a)+(b)] of the content of component (c) to the total content of components (a) and (b) is 0.005 or more and 0.3 or less. (a) Ingredients: Metal chelating agent (b) Component: Foaming surfactant (c) Component: Water-soluble polymer

The invention relates to a preparation method of a high-yellowing-resistance self-cleaning TPU (thermoplastic polyurethane) film, which comprises the following steps: mixing polyether glycol with nano silicon dioxide which accounts for 1-5% of the total weight of a base material; adding a solvent of ethanol or methanol, wherein the dosage of the solvent is 150-300% of the weight of the base material; stirring for 30-60 minutes at room temperature to form uniform dispersion liquid; adding a metal chelating agent solution containing EDTA (Ethylene Diamine Tetraacetic Acid) into the dispersion liquid, wherein the dosage is 0.2-1% of the total weight of the dispersion liquid; an anti-yellowing agent comprising anti-UV-385 and anti-UV-328 is added into the solution, the total amount of the anti-yellowing agent is 2%-5% of the weight of the solution, and the anti-yellowing agent is added after being mixed according to the proportion of 1: 1 or 1: 2; the base material solution is added into a reaction kettle, isocyanate containing MDI is slowly added, and the use amount of the isocyanate is 40%-60% of the total weight of the base material; adding a chain extender which accounts for 10%-20% of the total weight of the base material, and adding a catalyst; adding activated titanium dioxide nano-particles into the prepolymer, wherein the use amount of the activated titanium dioxide nano-particles is 0.5%-2% of the total weight; the activation method adopts plasma treatment.