58 results about "Metaphysis" patented technology

The humeral portion of a shoulder prosthesis includes a diaphyseal component configured for fixation within the humerus, a metaphyseal component, configured for removable implantation within the metaphysis of the humerus, and an engagement mechanism for removably engaging the two components. The metaphyseal component can initially include a convex articulating surface that can be replaced with a concave surface during the shoulder arthroplasty procedure or in a subsequent revision surgery. The metaphyseal component can also include a feature to facilitate removal of the component from the bone once it has been disengaged from the diaphyseal component.

A medical implant plate including at least two sets of apertures through an elongated shaft body to individually accommodate and orient set screws or pegs at various angles that may be selected depending on application, i.e., the apertures don't have fixed angled, but allow for a range of angles. Once the screw has been locked, the device becomes a fixed angled device. The screws or pegs laterally spaced relative to each other to resist torsion and to secure the plate against dislodgement. The body also includes a flared-end portion that accommodates and extends partially onto a metaphysis of a tubular bone of the hand while maintaining a low-profile to avoid soft-tissue irritation. The flared-end portion that extends on to the metaphysis does NOT have holes for screws but serves as a buttress. Screws that extend into the metaphysis come from the three holes located along the slightly angled portion of the plate.

An implant for shoulder arthroplasty includes a stem and optionally a head component or a cup component. The stem is sized and shaped to fit into an intramedullary canal of the humerus. The proximal portion of the stem has a concave taper and the distal portion of the stem has a taper. The distal taper includes an anterior-posterior taper and a medial-lateral taper. The shape of the stem loads the metaphysis of the humerus with a greater load than the load applied to the diaphysis of the humerus.

A humeral prosthetic head has a non-spherical articulation surface coupled with an intermediate component connecting the head and the humerus, the intermediate component connected to the epiphysis, metaphysis, or diaphysis, or to one or more additional components connected to the humerus. The intermediate portion provides for axial and angular offset of the head with respect to a connection to the humerus, using a curvilinear tapered engagement.

A method for arthroplasty includes using a self-locking prosthesis that has a member structured to transfer a load produced by the weight of a patient to a bone. An expandable bone-locking portion that is integral to the member includes a shape-memory material and expands to produce a locking force. A portion of the bone is removed to form an aperture in the bone. The bone-locking portion is inserted into the aperture, and a temperature increase causes a change from a contracted state to an expanded state resulting in expansion of the bone-locking portion so as to contact the inner surface. The expanding is sufficient to create a locking force at the junction between the inner surface and the bone-locking portion of the prosthesis and the majority of the locking force is applied at or above the metaphysis. The length/width ration of the prosthesis may be less than or equal to 5. The resulting reconstructed long-bone may have improved primary and long-term stability.

A tissue engineering cartilage construction method using bone matrix gelatin which comprises, using cartilage cell for isolated culture or base material stem cell for isolated culture to evoke cartilage cell i.e. seed cell, fetching New Zealand rabbit or human embryon os longum and metaphysic trabecular bone to construct bone matrix gel BMG, inoculating the seed cells harvested through isolated culture onto cortex bone or cancellous bone BMG for extracorporal culture.

The invention discloses a double-nail-hook metaphysis pressurizing fixing device which comprises a first fixing part, a second fixing part and a connecting part. The connecting part is used for connecting the first fixing part and the second fixing part. The first fixing part comprises two strip-shaped objects. The strip-shaped objects are used for penetrating through the fracture part of the metaphysis and being inserted into the backbone to be fixed. The connecting part is in a forked strip-shaped hook shape attached to the surface of the bone. Forked strips of the connecting part and the strip-shaped objects of the first fixing device are connected in a one-to-one corresponding mode. A plurality of pressurizing fixing holes are formed in the second fixing part. Pressurizing screws penetrate through the pressurizing fixing holes so that the second fixing part can be fixed to the backbone connected with the metaphysis. The pressurizing fixing device is convenient to take out, low in cost, and beneficial for healing the fracture part and preventing secondary injuries to normal bone tissue.

The invention discloses a method for preparing a novel individual degradable artificial intraosseous stent, which belongs to the technical field of biomedicine. The method comprises the following steps of making a light-cured resin mold of which the form is consistent with the marrow cavity of a tubular bone massive comminuted fracture segment by using a rapid forming technology; and pouring an artificial intraosseous stent by using a compound material. The stent has the advantages of easiness in operating, reliable curative effect, high bone healing speed and small quantity of complications when applied to operation of tubular bone massive comminuted fractures, can be particularly applied to treatment of comminuted fractures of tubular bone metaphysis, and has very high potential clinical application value.

The present invention provides a type of tibial near -end lock board, including main components and connecting components. The main components are used to fix the outer side of the proximal tibia;Forces, the head of the head wraps on the tibia near -end platform is fixed and fixed. The pole parts fit the outer sides of the tibial and orthopedic and fix it.Piece parts of the side column.The present invention realizes the fixation of the outer tibial side through the main component, and the design of the component of the parts to enhance the fixation of the rear column of the back column of the near -end platform of the tibia, so that the outer outer lock plate of the tibia can be used for the proximal fracture of the tibia, dry and dry.In the surgery of end fractures, joint fractures, and peripheral fractures of prosthesis; in addition, the head of the main component is wrapped in the outer side column of the near -end platform of the tibia, which is fixed and reliable than the existing curved surface bone plate.

A system for sizing the resected surface to provide metaphyseal referencing and to properly guide a tool into a central portion of the canal in the diaphysis. The system can include a sizing feature to approximate the size of the metaphysis. The system can also include a base configured to contact the metaphysis and a guide feature configured to guide a tool along a central portion of the canal in the diaphysis.

Provided is a method and an apparatus for extracting an edge of a distal radius metaphysis. The method includes: setting a region of interest including a distal radius in an X-ray image; setting a potential energy distribution of the region of interest by using a gradient of gray levels; setting a temporary edge adjacent to both sides of a distal radius metaphysis and a side of an epiphysis in the region of interest; and extracting a detailed edge of the distal radius metaphysis having minimum energy by adjusting the set temporary edge using a metropolis annealing technique.

The invention relates to a DNA library for detecting and diagnosing pathogenic genes of skeletal development disorders through a targeted high-throughput sequencing technology and application thereof. The library comprises 507 pathogenic genes of skeletal development disorders. According to the invention, 507 pathogenic genes of skeletal development disorders are preferably selected, a probe pool is designed, a target region library for 507 pathogenic genes of skeletal development disorders is established, and the library utilizes the high-throughput sequencing technology for sequencing to find pathogenic mutations, thereby providing genetic and molecular biological bases for clinical diagnosis. The DNA library provided by the invention has the characteristics of accuracy, rapidness, flexibility and low cost. The 507 genes involved in the invention include pathogenic genes of genetic diseases with skeletal development disorders as clinical manifestations, such as collagen dysplasia, metaphysic dysplasia, osteogenesis imperfecta and bone density reduction, mucopolysaccharide storage disease, cartilage dysplasia and the like, and have important significance and clinical value for diagnosis, differential diagnosis and accurate treatment of skeletal development disorders.

The present invention relates to an internal bone plate fixation device (1) for use as a means of synthesis in anatomical regions or epiphysis/metaphysis with poor coating of soft tissues, of the type comprising a bone plate (2) that is bilobate or having eight-like shape, comprising a pair of portions (23, 24) adapted to be respectively associated to the epiphysis and to the metaphysis of a bone and joined by a central portion (15) and in each of which is formed at least one through hole (3, 4) to receive a corresponding screw (5) for fixing to the bone. Advantageously, the bone plate (2) is flat with almost constant thickness and is delimited by opposite surfaces (6, 7) parallel with a single recess (8) or notch that is transversal to the longitudinal axis of bone plate (2) formed on only one (6) of said surfaces (6, 7), with the thickness (s) of the plate being less than a ninth of its maximum longitudinal extension (L).

The invention relates to a meniscus bracket and a preparation method thereof. The preparation method comprises the following steps: taking heterogeneous or allogeneic cancellous bone of femur or tibial metaphysis, removing surrounding attached tissues, and using an electric pendulum saw to cut out Cancellous bone slices with a predetermined thickness are soaked in distilled water after cleaning; the cancellous bone slices are processed into ring-shaped scaffolds after decalcification, fat-removing and protein removal; finally, the ring-shaped scaffolds are freeze-dried at -20°C and irradiated with cobalt 60 Sterilize and store at -80°C for more than 2 weeks to obtain a meniscus scaffold. The meniscal scaffold made of demineralized cancellous bone in the present invention has biological activity and can promote the adhesion and proliferation of cells; and the annular shape also increases the surface area, which is conducive to the full exchange of substances between cells and culture medium, and reduces Apoptosis, thereby increasing the number of cells.

The invention relates to a method for preparing a PLGA (polylactic-co-glycolic acid) modified biological factor microsphere supported bone substituted material. The method comprises the following steps: 1, preparing a drug-loaded chitosan microsphere from carboxymethyl chitosan, recombinant human adiponectin, recombinant human bone morphogenetic protein and sodium tripolyphosphate; 2, modifying the metaphysis, serving as a bone raw material, of a newborn calf articular head or tibia with a modifying agent, calcining the modified bone raw material at 800-1100 DEG C to completely remove the immunizing antigenicity to obtain modified calcined bone powder; and 3, preparing the PLGA modified biological factor microsphere supported bone substituted material from PLGA, the modified calcined bone powder and the drug-loaded chitosan microsphere. The PLGA modified biological factor microsphere supported bone substituted material has certain morphological and mechanical strength, and can be used for sustainably releasing biological active factors for promoting bone formation and locally releasing calcium and phosphor ions on a bone defect position.