38 results about "Pre analytical" patented technology

The invention is directed to a droplet actuator device and methods for integrating gel electrophoresis analysis with pre or post-analytical sample handling as well as other molecular analysis processes. Using digital microfluidics technology, the droplet actuator device and methods of the invention provide the ability to perform gel electrophoresis and liquid handling operations on a single integrated device. The integrated liquid handling operations may be used to prepare and deliver samples to the electrophoresis gel, capture and subsequently process products of the electrophoresis gel or perform additional assays on the same sample materials which are analyzed by gel electrophoresis. In one embodiment, one or more molecular assays, such as nucleic acid (e.g., DNA) quantification by real-time PCR, and one or more sample processing operations such as sample dilution is performed on a droplet actuator integrated with an electrophoresis gel. In one embodiment, an electrophoresis gel may be integrated on the top substrate of the droplet actuator.

Analysis system (10, PROSAD) for the quantitative chemical analysis of samples (A, A-1, A- 2,....), preferably but not solely in the medical field, comprising detection instrumentation or equipment (30) designed to detect the quantity of the target analytes ( [x], [y], [z] ) present in the various samples (A, A1) to be analysed, which in turn comprises a chromatography system (31), an ion source (32) and a mass spectrometer (33); a data processing system (40, 42, 43, 44) designed to process the quantitative data of the target analytes present in the samples analysed, as detected by the detection equipment (30); and an innovative database (41) containing corrective and control data and coefficients (K, C, K1) to be used to calibrate and correct the instrumental response of the specific detection equipment (30) used to analyse the samples, wherein said corrective and control data and coefficients are determined and acquired by the database at a preliminary stage (51, 52) before the actual analysis of the samples, wherein the sample to be analysed is prepared with a universal dilution solution in order to minimise the corresponding matrix effect, and wherein the data processing system determines the quantitative data of the target analytes present in the samples analysed by processing the quantitative data (Q) detected by the detection equipment, namely the mass spectrometer, taking account of the corrective and control data and coefficients contained in the database. By comparison with the analysis systems currently in use, the system for quantitative analysis of samples according to the invention presents the significant advantage of not requiring, in order to calibrate the detection equipment during the analysis of multiple samples, continuous and expensive use, for each analysis, of commercial standards of the target analytes to be quantitated.

The inventive device comprises a pre-analytical module (1) which is provided with at least one tube stirrer (8) for homogenising blood and preventing clot formation and disposed on a line (4) for single-tube transfer between an area for storing analysable tubes (2), at least one unitary operating whole blood analyser (3) and automatic tube-loading / unloading means (27, 28, 29) arranged between the tube stirrer (8) and the single-tube transfer line (4). The invention is suitable for blood analysers.

The present invention discloses a topological graph-based intelligent navigation method and system, and relates to the field of computer technologies. A specific implementation manner of the method comprises: determining a navigable area view based on a constructed topological graph according to current position information; obtaining scene data, wherein the scene data comprises at least a scene image, a scene depth map, and a scene analytical diagram; and determining a behavior decision according to the navigable area view, the scene data, and a navigation model. The method is based on a multi-index navigation model, and the navigable area view is determined based on the constructed topological graph. Compared with a mapless mode, the method can be used to improve real-time navigation accuracy under the constraint of a GPS, and improve navigation robustness with incomplete dependence of the GPS.

A flexible diagnostic workstation comprises is equipped to read label information on well strips of loaded well plates and on loaded reagent kit holders, automatically perform the pre-analytical steps of an immuno-assay which consists of a sequence of operations in accordance with scheduled test requirements for each microwell, read the results according to either a standard singleplex ELISA or multiplex test format as indicated by the well strip label, and report the results.

The present invention relates to multi-user analytical system and corresponding device and method. The device includes an interception module configured to intercept a user's request for a first core object, wherein the first core object belongs to core object; a transformation module configured to create, in response to the request being a creation request, the first core object specific to the user; a mapping module configured to interpret, in response to the request being a non-creation request, the request as a request for the first core object specific to the user. The present invention also includes an isolation method for the multi-user analytical system. The technical solutions provided in the present invention can effectively enable multiple users to share physical resources in the analytical system, and the users are isolated from each other in a substantially transparent way.

An analyzer includes a display, measurement hardware configured to perform a measurement on a sample, and a controller. The controller is in communication with the display and the measurement hardware and is configured to communicate, via the display, a first pre-analytical procedure of the sample prior to measurement of the sample. The controller is also configured to maintain the analyzer in a state associated with the first procedure for an amount of time equal to a time needed for performing the first procedure. After the time needed for performing the first procedure has elapsed, the controller is configured to communicate, via the display, a second pre-analytical procedure of the sample prior to measurement of the sample.

An analyzer includes a display, measurement hardware configured to perform a measurement on a sample, and a controller. The controller is in communication with the display and the measurement hardware and is configured to communicate, via the display, a first pre-analytical procedure of the sample prior to measurement of the sample. The controller is also configured to maintain the analyzer in a state associated with the first procedure for an amount of time equal to a time needed for performing the first procedure. After the time needed for performing the first procedure has elapsed, the controller is configured to communicate, via the display, a second pre-analytical procedure of the sample prior to measurement of the sample.

An automated, refrigerated specimen management system (ARSIMS) to hold sealed and / or opened sample / specimen tubes and / or containers that can be in the pre-analytical, in-process, or post-analytical phase of processing. The ARSIMS ensures that each sample / specimen tube, whether it is sealed, capped, closed or open, can be stored at an ideal storage temperature according to the particular phase of processing and as appropriate for the combination of sample / specimen type and analyte(s) to be tested.

The invention is suitable for the technical field of monitoring, and provides an image stabilizing control method and an image stabilizing control system for a video image and a video analytical system. The method comprises the following steps of: acquiring stable image subblocks according to angular point information in the image subblocks for pre-dividing an original monitoring image; calculating the motion vector of a video image frame of the original monitoring image relative to a background image according to the selected image subblocks; rectifying the original monitoring image according to the calculated motion vector of the video image frame of the original monitoring image relative to the background image to obtain a rectifying image; and matching the original monitoring image and the rectifying image with the background image respectively to acquire an image for background modeling. By the method, the defect of the blindness of selecting the image subblocks in the conventional image stabilizing algorithm is overcome, and the accuracy of estimation is improved.

The present invention relates to a method for the pre-analytical treatment of a blood sample to be analyzed, comprising a suitable sample matrix for said sample and suitably centrifuging said sample. The present invention further relates to an apparatus, characterized in that it comprises suitable components for performing the method according to the present invention. The present invention further relates to the use of said apparatus according to the present invention for the automated pre-analytical treatment of a blood sample to be analyzed according to the present invention.