The invention discloses a primer group, kit and method for evaluating chronic cardiac failure prognosis, and belongs to the field of gene detection. The primer group comprises a first upstream primer,a first downstream primer, a second upstream primer, a second downstream primer, a third upstream primer, a third downstream primer, a fourth upstream primer, a fourth downstream primer, a fifth upstream primer, a fifth downstream primer, a sixth upstream primer, a sixth downstream primer, a seventh upstream primer, a seventh downstream primer, an eighth upstream primer and an eighth downstream primer. Genes amplified by the primer group correspond to eight risk alleles sensitive to prognosis correspondingly, and accuracy and comprehensiveness of the evaluated result can be ensured; and according to the method, by conducting sequencing and data interpretation on a target amplification region, mutations relevant to prognosis can be accurately identified, thus the variety and pathogenesis of diseases are judged, and a timely and reliable detection report is provided for clinic.