Patents
Literature
3 results about "Sirtuin" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Sirtuins are a class of proteins that possess either mono-ADP-ribosyltransferase, or deacylase activity, including deacetylase, desuccinylase, demalonylase, demyristoylase and depalmitoylase activity. The name Sir2 comes from the yeast gene 'silent mating-type information regulation 2', the gene responsible for cellular regulation in yeast.
A sirtuin protein promoter and uses thereof
The application discloses a SIRT protein promoter and application thereof, and belongs to the technical field of cosmetics, and particularly relates to a SIRT protein promoter; the active ingredient of the SIRT protein promoter is oligopeptide-6; the oligopeptide-6 can not only activate an AMPK signal path, up-regulate NAMPT gene expression, and improve intracellular NAD + level, thereby activating SIRT protein in dependence on NAD + ; and can effectively promote collagen production, and realize the effects of anti-wrinkle and skin tightening.
Owner:HANGZHOU PEPTIDE BIOCHEM +1
Use of the pharmaceutical composition in the preparation of a medicament for the prevention or treatment of diseases related to the silencing information regulator 7 protein
PendingCN122079899AEnhanced inhibitory effectOrganic active ingredientsSenses disorderBenzimidazole derivativeDisease
This invention relates to a benzothiazole or benzimidazole derivative, a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the derivative as an active ingredient for the prevention or treatment of diseases related to the Silent Information Modulator (SIRTUIN) 7 protein, which exhibits excellent inhibitory activity against the SIRTUIN 7 protein and can be used for the prevention or treatment of diseases related to the SIRTUIN 7 protein.
Owner:KOREA RES INST OF CHEM TECH
An anti-aging composition for improving cardiovascular function, and a preparation method and application thereof
PendingCN122320212AAtp productionQuercitrin
The present application relates to an anti-aging composition for improving cardiovascular function and a preparation method and application thereof, and the composition comprises L-ergothioneine, honokiol, quercetin and coenzyme Q10. The present application creatively designs an anti-aging composition for improving cardiovascular aging, which improves cardiovascular aging from four dimensions of "myocardial energy supply + anti-hypertrophy + endothelial protection + anti-oxidation". Coenzyme Q10 can restore myocardial mitochondrial ATP production, honokiol can reverse myocardial hypertrophy through NAD+ deacetylase, quercetin can improve endothelial function and reduce blood pressure, and L-ergothioneine can protect vascular endothelial cells from oxidative damage and inhibit the formation of ox-LDL. Through research, it is found that the four can cooperate and synergize with each other, and can jointly play an excellent role in improving cardiovascular aging, and achieve multiple protection for cardiovascular aging.
Owner:GUANGZHOU FANZHIRONG COSMETICS CO LTD