Patents
Literature
4 results about "Tensin" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Tensin was first identified as a 220 kDa multi-domain protein localized to the specialized regions of plasma membrane called integrin-mediated focal adhesions (which are formed around a transmembrane core of an αβ integrin heterodimer). Genome sequencing and comparison have revealed the existence of four tensin genes in humans. These genes appear to be related by ancient instances of gene duplication.
Pre-eclampsia marker and application and kit thereof
The invention discloses a preeclampsia marker as well as application and a kit thereof. Comprising phosphatase and tension protein (PTEN), and the marker can be used for preparing a serological detection preeclampsia diagnostic reagent or diagnostic tool to perform early screening on preeclampsia risk population and fill the blank of current preeclampsia serological diagnosis. The invention belongs to the technical field of medicine. Furthermore, the invention also provides an ELISA kit for detecting preeclampsia, the sampling means is non-invasive and non-invasive, high-precision endoscope equipment is not needed, the kit can be applied to primary medical institutions, the early diagnosis of preeclampsia and the adoption of prevention means for intervention are facilitated, and the kit has good application value.
Owner:HUADU DISTRICT GUANGZHOU CITY PEOPLES HOSPITAL
Treatment of solid tumors with implantable polymers having small molecules
Implantable polymers that release a therapeutic agent near a tumor in a patient are disclosed. In some embodiments, a polyethylene glycol hydrogel can release a small molecule, such as a STING agonist, near a phosphatase and tensin homolog (PTEN)-null triple negative breast cancer (TNBC) in the patient.
Owner:DANA FARBER CANCER INSTITUTE INC +1
Treatment of solid tumors with implantable polymers with small molecules or cells
Implantable polymers that release a therapeutic agent near a tumor in a patient are disclosed. In some embodiments, a polyethylene glycol hydrogel can release a STING agonist and / or CAR-T cells near a phosphatase and tensin homolog (PTEN)-deficient triple negative breast cancer (TNBC) in the patient.
Owner:DANA FARBER CANCER INSTITUTE INC +1
Irrepairzepine and its derivatives, methods for synthesizing said compounds, as Anti-malignant glioblastoma agents
The present invention relates to a compound of the formula (I) wherein the substituents R1, R2, R3 and R4 are as defined in the disclosure of this invention. Said compounds are for treating brain cancer, wherein brain cancer is glioblastoma and such glioblastoma is Phosphatase and Tensin Homolog deleted on Chromosome 10 or PTEN.
Owner:CHULABHORN FOUND