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32 results about "Thionazin" patented technology
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Thionazin is a chemical compound used in nematicides.
Polymerization inhibitor and polymerization inhibiting method for (methyl) acrolein, (methyl) acrylic acid and esters thereof
InactiveCN104016821AOrganic compounds purification/separation/stabilisationOrganic compound preparationNitro compoundAcrolein
The invention provides a polymerization inhibiting method for (methyl) acrolein, (methyl) acrylic acid and esters thereof in production, transportation and storage processes. The polymerization inhibiting method is characterized in that a novel compound polymerization inhibitor is added to the solutions of (methyl) acrolein, (methyl) acrylic acid and esters thereof. The compound polymerization inhibitor involved with the polymerization inhibiting method comprises compound active ingredients formed by blending a quinone compound, an amine compound, an N-oxo-compound, and one or more than one of phenolic compounds, phenothiazine compounds and nitro compounds. The polymerization inhibitor is more effective than a single compound in polymerization inhibition effect. The polymerization inhibitor has an excellent polymerization inhibition effect in the processes of synthesis, purification, recovery and the like of (methyl) acrolein, (methyl) acrylic acid and esters thereof.
Owner:INST OF PROCESS ENG CHINESE ACAD OF SCI
Green material, preparation method and application thereof
ActiveCN104650067AImprove luminous efficiencyOrganic chemistrySolid-state devicesPhotoluminescencePhenothiazine derivative
The invention discloses a preparation method and application of a phenothiazine derivative. A green organic electroluminescence material disclosed by the invention is based on phenylimidazole and phenothiazine and has the structure formula shown in description, wherein R1, R2 and R3 can be same or different. The phenothiazine derivative has green photoluminescence and high luminous emission efficiency and can be taken as a green material to be applied to electroluminescence devices.
Owner:JILIN OPTICAL & ELECTRONICS MATERIALS
Preparation method and medicinal use of thiazide compound in Siberian Cocklour Fruit
InactiveCN108514568APrevent proliferationReduce arthritis indexAntipyreticAnalgesicsAcetic acidTreatment effect
The invention relates to a preparation method and a medicinal use of a thiazide compound in Siberian Cocklour Fruit. Effective parts for preventing and / or treating rheumatism and rheumatoid arthritisin ethanol extract of Siberian Cocklour Fruit are screened, ethyl acetate components and n-butanol components in the 50-90% ethanol extract of the Siberian Cocklour Fruit have significant treatment effects on the rheumatism and rheumatoid arthritis, and the n-butanol components in the 50-90% ethanol extract of the Siberian Cocklour Fruit are separated and purified to obtain eleven concrete compounds, the compounds have an obvious inhibition effect on TNF-alpha induced RAFLS cell proliferation, and especially xanthiside has the most obvious effect, and is suitable for preventing and treating the rheumatism and rheumatoid arthritis.
Owner:HEILONGJIANG UNIV OF CHINESE MEDICINE
Phenothiazine double-photon photoacid initiator and preparation method thereof
InactiveCN101037422AThe synthesis method is simpleFew reaction stepsOrganic chemistryPhotosensitive materials for photomechanical apparatusPhotoacidPhotoinitiator
A dibenzothiazine two-photon acidic photoinitiator includes: having the dibenzothiazine as initial material, subsequently preparing the intermediate (I) N-alkyldibenzothiazine, (II) 3,7-bisformacyl-N-alkyldibenzothiazine and (III) 3,7-bis p-dialkylaminostyryl-N-alkyldibenzothiazine, finally synthesizing the target product by intermediate (III). The composition has a high stability and is a perfect two-photon acidic photoinitiator no matter being solution or film.
Owner:ANHUI UNIVERSITY
Small molecular oxothiazine derivative and application thereof
ActiveCN111559990AFunction increaseReduce inactivation rateOrganic active ingredientsNervous disorderOrganic synthesisInhibitory receptors
The invention belongs to the field of organic synthetic medicines, and concretely relates to a small molecular oxothiazine derivative. The general formula is shown in the specification. The small molecular oxothiazine derivative can be used as a forward allosteric regulator of an AMPA receptor, and the compound is proved to be capable of positively regulating the AMPA receptor, so that the conformation after an agonist (such as endogenous neurotransmitter glutamic acid) is combined with the receptor is more stable, the inactivation rate of the receptor is reduced, the desensitization of the receptor is inhibited, and the function of the AMPA receptor is enhanced.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV
Synthesis method of 1, 2-benzothiazine compound
ActiveCN110698431AImplement the buildRaw materials are easy to obtainOrganic chemistryPtru catalystBiochemical engineering
The invention discloses a synthesis method of 1, 2-benzothiazine compound. According to the synthesis method of the 1, 2-benzothiazine compound, sulfoximine is used as a guide group, transition metalpalladium is used as a catalyst, the sulfoximine compound and an aryne precursor are used as reaction substrates in the presence of fluoride, and a series of 1, 2-benzothiazine compounds are synthesized through cyclization reaction activated by C-H or N-H bonds. The method has the advantages of simple and accessible raw materials and mild reaction conditions, implements the construction of C-C andC-N bonds, shortens the synthesis route, and conforms to the concept of environment friendliness.
Owner:SHAANXI NORMAL UNIV
Method for synthesizing 1,2-benzothiazine compound by rhodium (III) catalyzed C-H activation reaction
The invention relates to a method for synthesizing a 1,2-benzothiazine compound by rhodium (III) catalyzed C-H activation reaction. According to the invention, S-aryl imino sulfone is used as a raw material, and a 1,2-benzothiazine skeleton is efficiently constructed through a C-H activation / cyclization reaction catalyzed by transition metal rhodium with a carbene precursor iodine ylide. Compared with a traditional synthesis method, the method does not need additional additives, and post-treatment is simple and convenient; high temperature and high pressure are not needed, reaction time is short, and conditions are relatively mild; the method has the advantages of wide substrate application range, simple operation steps and high product yield.
Owner:SICHUAN UNIV
Fragrance pro-accords and aldehyde and ketone fragrance libraries
The present invention relates to novel heterocyclic pro-fragrances, preferably oxazolidines, tertahydro-1,3-oxazines, thiazolidines, or tetrahydro-1,3-thiazines, more preferably oxazolidines, or tertahydro-1,3-oxazines, most preferably oxazolidines, which are capable of sustained release of fragrance raw material ketones and aldehydes and to fragrance delivery systems which comprise said pro-fragrances.
Owner:THE PROCTER & GAMBLE COMPANY
N-substituted benzoyl phenothiazine compounds as well as preparation method and application thereof
The invention relates to N-substituted benzoyl phenothiazine compounds as well as a preparation method and application thereof, and particularly relates to N-substituted benzoyl phenothiazine compounds having a structure as shown in a formula I described in the specification as well as a preparation method of the compounds, pharmaceutical compositions taking the N-substituted benzoyl phenothiazine compounds having a structure as shown in the formula I as active ingredients and use of the pharmaceutical compositions for preventing or treating diseases related to an arginine vasopressin V1a receptor, an arginine vasopressin V1b receptor, an arginine vasopressin V2 receptor, a sympathetic nervous system or a rennin-angiotensin-aldosterone system.
Owner:TIANJIN INSTITUTE OF PHARMA RESEARCH
Oxothiazine compound and application thereof
ActiveCN111518058AFunction increaseReduce inactivation rateOrganic active ingredientsNervous disorderOrganic synthesisInhibitory receptors
The invention belongs to the field of organic synthetic medicines, in particular relates to an oxothiazine compound. The general formula is shown in the specification, the oxothiazine compound can beused as a forward allosteric regulator of an AMPA receptor; the compound is proved to be capable of positively regulating the AMPA receptor, so that the conformation after an agonist (such as endogenous neurotransmitter glutamic acid) is combined with the receptor is more stable, the inactivation rate of the receptor is reduced, the desensitization of the receptor is inhibited, the function of theAMPA receptor is enhanced, the drug-likeness of the AMPA receptor is remarkable, and the market prospect is wide.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV
Phenothiazine compound as well as preparation method and application thereof
PendingCN113264903AStrong inhibitory activityImprove biological activityOrganic chemistryAntineoplastic agentsMorpholinePharmacophore
The invention discloses a phenothiazine compound which has the advantages of novel structural general formula and framework, high efficiency, low toxicity and better inhibitory activity on LSD1. The invention also discloses a preparation method of the compound. The preparation method has the characteristics of mild reaction conditions, simplicity in operation and high reaction yield. According to the invention, phenothiazine is taken as a raw material, active groups are respectively introduced to a parent of phenothiazine, and new phenothiazine pharmacophores are synthesized; and phenothiazine compounds are designed and synthesized by modification with piperazine, morpholine, piperidine and other groups. The compound retains the activity of phenothiazine and also has the characteristics of modification groups, so that the biological activity of original molecules is improved, and the anti-tumor activity of target molecules is improved. The invention also discloses an application of the compound in preparation of LSD1-targeted antitumor drugs, and the compound shows good inhibitory activity on LSD1 and shows good development potential.
Owner:ZHENGZHOU UNIV
A kind of phenothiazine co-sensitizer and its preparation method and application
ActiveCN110343100BImprove conversion efficiencyGood for filling the adsorption gapLight-sensitive devicesOrganic chemistryElectron donorPorphyrin
Owner:JIANGSU UNIV OF TECH
Molecularly imprinted polymer, chemiluminescence kit and detection method specific for phenothiazine drug family
InactiveCN108484816BEnsure safetyStrong toleranceOther chemical processesChemiluminescene/bioluminescenceMeth-Functional monomer
The invention discloses molecularly imprinted polymer with phenothiazine drug specificity, a chemiluminiscence kit and a detection method. The molecularly imprinted polymer is prepared by taking 2-trifluoromethyl phenothiazine as a molecular template, methacrylic acid as functional monomer, azodiisobutyronitrile as an initiator, and ethylene dimethacrylate as a crosslinking agent. The chemiluminiscence kit is prepared by taking a molecularly imprinted compound as a core reagent, imidazole as a catalyst, and bis (2, 4, 6-trichlorophenyl) oxalic ester and hydrogen peroxide as chemiluminescence reagents, and meanwhile the detection method adopting the kit is further provided. The molecularly imprinted polymer can capture various phenothiazine drugs, and the chemiluminiscence kit can accurately, rapidly and efficiently detect various phenothiazine drugs.
Owner:HEBEI AGRICULTURAL UNIV.
Phenothiazine organic small molecule donor and preparation method thereof
ActiveCN105294735ALarge conjugated structureGood hole transport propertiesOrganic chemistryMethylene DichlorideHigh energy
The present invention discloses a phenothiazine organic small molecule donor and a preparation method thereof. The preparation method comprises: under a N2 atmosphere, adding POCl3 to N,N-dimethylformamide (DMF), carrying out a stirring reaction, adding a DMF solution of 7,14-dialkyl-benzo[1,4]-thiazino[2,3-b]phenothiazine, carrying out a heating reflux reaction, carrying out water washing filtration to remove the DMF and the POCl3, drying, carrying out column chromatography separation to obtain an intermediate 1, taking the intermediate 1, ammonium acetate and 3-alkyl rhodanine, dissolving in acetic acid, carrying out a reflux reaction, pouring the reaction liquid into cold water after completing the reaction, extracting with methylene chloride, carrying out rotating drying on the organic phase, and carrying out column chromatography separation to obtain the target product. According to the present invention, the donor small molecule has characteristics of large conjugating structure, good hole-transporting property, narrow band gap, good light absorption performance, good solubility, high energy level and PCBM matching degree, and the like.
Owner:WUHAN INSTITUTE OF TECHNOLOGY
Method for simultaneously and quantitatively detecting contents of epinephrine, phenothiazine and atropine drugs in sample
The invention discloses a method for simultaneously and quantitatively detecting the contents of epinephrine, phenothiazine and atropine drugs in a sample. The method comprises the following steps oftaking a to-be-detected sample solution, detecting by the high performance liquid chromatography, and carrying out gradient elution by using a sodium heptanesulfonate solution as a mobile phase A andmethanol as a mobile phase B. According to the method, the sample is simple to prepare and operate, at most three or eight compounds can be detected at the same time, the separation condition betweenchromatographic peaks is good, and the method is suitable for detecting the content of epinephrine receptor stimulant drugs, phenothiazine drugs and atropine in food, drugs, blood products and the like.
Owner:CHINA INST OF VETERINARY DRUG CONTROL
Novel improved method for synthesizing diaminophenothiazine compounds
PendingUS20220235019A1High puritySimple methodOrganic chemistryChemical synthesisPharmaceutical medicine
The present invention relates to chemical synthesis and purification. Specifically, the present invention relates to a novel and improved method of synthesizing high purity diaminophenothiazine compounds of Formula I, specifically Methylene Blue and its pharmaceutically acceptable salt or hydrates thereof. The present invention relates to an improved method of synthesizing Methylene Blue compound of higher purities than those achievable by using known methods of synthesis as per the requirements of the international pharmacopoeias like USP and EP.
Owner:AGRAWAL ACHAL NARENDRAKUMAR
Preparation method of N-heterocyclic carbene catalytic axial chiral 1, 3-thiazine compound
The invention discloses an axially chiral 1, 3-thiazine compound (Z)-N-(4-ketone-3-phenyl-3, 4-dihydro-2H-1, 3-thiazine-2-subunit) substituted amide derivative, which is characterized in that the derivative is represented by a general formula (1): wherein Ar is substituted benzene or naphthalene; R1 is substituted benzene, naphthalene, furan or alkyl; R2 is a halogen atom or a phenyl group; R3 isalkyl or phenyl.
Owner:GUIZHOU UNIV
Preparation method of benzo[e][1,4,3]oxathiazine-1,1-dioxide derivative
PendingCN114059090AReaction raw materials are readily availableHigh yieldElectrolysis componentsElectrolytic organic productionPtru catalystOrganic synthesis
The invention discloses a preparation method of a benzo[e][1,4,3]oxathiazine-1,1-dioxide derivative and belongs to the technical field of organic synthesis. According to the method, relatively simple raw materials are used, and the benzoxthiazine derivative is directly synthesized for the first time through an electrochemically promoted smiles rearrangement reaction. According to the scheme, a precious metal catalyst and an oxidizing agent are unnecessary, reaction raw materials are easy to obtain, the yield is high, reaction conditions are mild, reaction time is short, the substrate range is wide, and aftertreatment is simple, convenient and green.
![Preparation method of benzo[e][1,4,3]oxathiazine-1,1-dioxide derivative](https://images-eureka.patsnap.com/patent_img/18d5c95e-fa88-4d8e-a257-9f309fd8765f/BDA0003365635400000021.png "Preparation method of benzo[e][1,4,3]oxathiazine-1,1-dioxide derivative")
![Preparation method of benzo[e][1,4,3]oxathiazine-1,1-dioxide derivative](https://images-eureka.patsnap.com/patent_img/18d5c95e-fa88-4d8e-a257-9f309fd8765f/BDA0003365635400000031.png "Preparation method of benzo[e][1,4,3]oxathiazine-1,1-dioxide derivative")
![Preparation method of benzo[e][1,4,3]oxathiazine-1,1-dioxide derivative](https://images-eureka.patsnap.com/patent_img/18d5c95e-fa88-4d8e-a257-9f309fd8765f/BDA0003365635400000032.png "Preparation method of benzo[e][1,4,3]oxathiazine-1,1-dioxide derivative")
Owner:FUZHOU UNIV
Lubricant Composition and Method of Preparing Copolymer Using the Same
ActiveUS20210009919A1Improve production yieldAvoid cloggingAdditivesBase-materialsPolymer scienceHydroquinone Compound
A lubricant composition includes a base oil, a phenothiazine-based polymerization inhibitor, and a polymerization inhibitory accelerator including a hindered phenol-based compound and a hydroquinone-based compound. A self-polymerization in a polymerizing process is suppressed by an interaction between the polymerization inhibitor and the polymerization inhibitory accelerator. A method of preparing a copolymer using the lubricant composition is also provided.
Owner:SK GEO CENTRIC CO LTD +1
3, 4-dihydro-2H-1, 3-thiazine derivative and preparation method thereof
ActiveCN111848547ANo protectionEasy to operateOrganic chemistryAgainst vector-borne diseasesChemical synthesisPtru catalyst
The invention belongs to the field of chemical synthesis, and particularly relates to a 3, 4-dihydro-2H-1, 3-thiazine derivative and a preparation method thereof. The structural formula of the 3, 4-dihydro-2H-1, 3-thiazine derivative is shown in the specification, and the preparation method of the 3, 4-dihydro-2H-1, 3-thiazine derivative comprises the following steps: taking alpha-enol dithioesterand 1, 3, 5-triazine as initial raw materials, taking dichloroethane as a reaction solvent, and simply and efficiently synthesizing the thiazine derivative at 60 DEG C in one step. According to the method, a precious metal catalyst is not used in the reaction, the reaction operation is simple, the post-treatment is convenient, the yield is generally very high, and inert gas protection is not needed in the preparation process.
Owner:SHENZHEN POLYTECHNIC
A kind of synthetic method of 1,2-benzothiazine compounds
ActiveCN110698431BImplement the buildRaw materials are easy to obtainOrganic chemistryArylPtru catalyst
The invention discloses a method for synthesizing 1,2-benzothiazine compounds. Sulfoximine is used as a guiding group, transition metal palladium is used as a catalyst, and in the presence of fluoride, a sulfoximine compound is used. A series of 1,2-benzothiazine compounds were synthesized by cyclization reaction activated by C-H or N-H bonds with aryl alkyne precursors as reaction substrates. The present invention has simple and easy-to-obtain raw materials, mild reaction conditions, realizes the construction of C-C and C-N bonds, shortens the synthesis route, and conforms to the concept of green environmental protection.
Owner:SHAANXI NORMAL UNIV
Method for removing dust thionazin in petroleum smelting chimney
InactiveCN108744834AHas the function of spraying and dust removalImprove cleaning efficiencyCombination devicesWater sourceHigh pressure water
The invention discloses a method for removing dust thionazin in a petroleum smelting chimney. The method is characterized in that high pressure water flow has the effects of spraying, removing dust, improving the dust removal efficiency and relieving environment contamination, and the method is applicable to dust and waste gas environment-friendly processing industries; a speed reduction motor (20) is started, a first chain wheel is driven to rotate clockwise, meanwhile, a chain drives a second chain wheel to rotate synchronously, a connecting plate (23) fixed to a chain (24) drives a high pressure water draining pipe (13) to move backwards, when a limiting block touches a limiting switch B, the speed reduction motor rotates anticlockwise, and the high pressure water draining pipe (13) isdriven to move forwards; when a limiting switch A is touched, the speed reduction motor (20) rotates clockwise, and so on; accordingly, the high pressure water draining pipe (13) is driven to move forwards and backwards, and the whole board of a filter net (4) is flushed; after a power source of the speed reduction motor is turned off and a high pressure water source is closed, the high-pressure flushing function is disabled.
Owner:QINGYANG ENERGY CHEM GRP WODE PETROLEUM TECH
Diaminophenothiazine compounds, a method for preparing same and uses thereof
Owner:PHARMA HYDRO DEV PHD
Processes for preparing oxathiazin-like compounds
Oxathiazin-like compounds, processes for making new oxathiazin-like compounds, compounds useful for making oxathiazin-like compounds, and their uses are disclosed. Processes of treating patients suffering from cancers, bacterial infections, fungal infections and / or viral infections by administering oxathiazin-like compounds are also disclosed. These compounds were found to have significantly longer half-life compared to taurolidine and taurultam.
Owner:GEISTLICH PHARMA
Thienothiazine compound having anti-inflammatory and analgesic properties and method of making and using the same
InactiveUS7125868B2Eliminate side effectsPromising anti-inflammatory and analgesic medicineOrganic chemistryAntipyreticMedicineAnti-inflammatory analgesics
The present invention is related to a type of thienothiazine compounds having molecular structure of formula (1) and their pharmaceutically acceptable salts or solvates. The present invention is also related to the method of producing the formula (1) compound, an anti-inflammatory and analgesic pharmaceutical composition containing the formula (1) compound, and the method of using the formula (1) compound to prepare anti-inflammatory and analgesic medicine
Owner:LI JING
A kind of small molecule oxathiazide derivative and its application
ActiveCN111559990BFunction increaseReduce inactivation rateOrganic active ingredientsNervous disorderOrganic synthesisInhibitory receptors
The invention belongs to the field of organic synthetic medicine, and specifically relates to a small-molecule oxathiazine derivative, whose general formula is as follows: the small-molecule oxthiazine derivative can be used as a positive allosteric regulator of AMPA receptors, which proves that The compound can positively regulate the AMPA receptor, and can make the conformation of the agonist (such as endogenous neurotransmitter glutamate) more stable after binding to the receptor, thereby reducing the inactivation rate of the receptor and inhibiting the desensitization of the receptor. Enhance the function of AMPA receptors.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV
A kind of oxathiazide compound and its use
ActiveCN111518058BFunction increaseReduce inactivation rateOrganic active ingredientsNervous disorderOrganic synthesisAgonist
Owner:WEST CHINA HOSPITAL SICHUAN UNIV
Green method for synthesizing [1, 2] thiazine derivatives
PendingCN114133362AWide applicabilityCatalytic reaction is green and sustainableOrganic chemistryAlkanePtru catalyst
The invention discloses a green method for synthesizing [1, 2] thiazine derivatives, and belongs to the technical field of green chemistry and organic synthesis. The [1, 2] thiazine derivative containing alkane, olefin, halogen and heterocyclic ring is rapidly prepared under the conditions of room temperature, opening and neutrality, the catalyst is MBrx (M is Fe < 2 + >, Fe < 3 + >, Ce < 3 + > and the like, x is 2-3), and the only oxidant is H2O2. According to the present invention, the wide substrate synthesis and the amplification preparation of the [1, 2] thiazine derivative using H2O2 as the oxidizing agent are achieved for the first time, the catalytic reaction is green and sustainable, and the use of the expensive and complex catalyst is avoided. The by-product is H2O, and the problems of environmental destruction, low yield and the like caused by catalytic reaction of many other strong oxidants are solved. The method is mild in reaction condition, simple in reaction process, high in yield, safe and environmentally friendly, conforms to the green chemistry concept, is wider in applicability, has wide development prospects and application prospects, and is expected to be widely applied to the fields of organic synthesis, medicines, pesticides, probes and the like.
![Green method for synthesizing [1, 2] thiazine derivatives](https://images-eureka.patsnap.com/patent_img/c744385a-9932-4c4c-845a-5c20a8c1be3d/HSA0000259893050000011.png "Green method for synthesizing [1, 2] thiazine derivatives")
![Green method for synthesizing [1, 2] thiazine derivatives](https://images-eureka.patsnap.com/patent_img/c744385a-9932-4c4c-845a-5c20a8c1be3d/HSA0000259893050000021.png "Green method for synthesizing [1, 2] thiazine derivatives")
![Green method for synthesizing [1, 2] thiazine derivatives](https://images-eureka.patsnap.com/patent_img/c744385a-9932-4c4c-845a-5c20a8c1be3d/HSA0000259893050000031.png "Green method for synthesizing [1, 2] thiazine derivatives")
Owner:BEIJING UNIV OF CHINESE MEDICINE
Method for synthesizing 1-hydroxyphenothiazine compound
ActiveCN114213359AThe synthetic route is simpleSynthetic raw materials are readily availableOrganic chemistryAgainst vector-borne diseasesOrganic synthesisCatalytic oxidation
The invention belongs to the technical field of organic synthesis, and relates to a synthesis method of phenothiazine compounds, in particular to a method for synthesizing 1-hydroxy phenothiazine compounds. The method comprises the following steps: taking an o-mercaptoaniline compound and a catechol compound as raw materials; the method comprises the following steps: oxidizing a catechol compound into an o-benzoquinone compound, carrying out an S-substitution reaction on the o-benzoquinone compound and an o-mercaptoaniline compound to synthesize an intermediate diphenyl sulfide compound, and carrying out catalytic oxidation dehydroxylation cyclization on the intermediate diphenyl sulfide compound to synthesize the 1-hydroxyphenothiazine compound. The method has the advantages of simple synthetic route, easily available synthetic raw materials, mild reaction conditions, high reaction efficiency, cheap catalyst, high activity, simple post-treatment and less waste, and has strong application prospects.
Owner:ZHENGZHOU UNIV
N-substituted benzenesulfonyl phenothiazine compound and its preparation method and use
The invention relates to N-substituted benzenesulfonyl phenothiazine compounds as well as a preparation method and application thereof, and particularly relates to N-substituted benzenesulfonyl phenothiazine compounds having a structure shown in a formula I described in the specification as well as a preparation method thereof, pharmaceutical compositions taking the N-substituted benzenesulfonyl phenothiazine compounds with a structure as shown in the formula I as active ingredients and use of the pharmaceutical compositions for preventing or treating diseases associated with an arginine vasopressin V1a receptor, an arginine vasopressin V1b receptor, an arginine vasopressin V2 receptor, a sympathetic nervous system or a rennin-angiotensin-aldosterone system.
Owner:天津天诚新药评价有限公司
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