The invention discloses a green method for synthesizing [1, 2]
thiazine derivatives, and belongs to the technical field of
green chemistry and
organic synthesis. The [1, 2]
thiazine derivative containing
alkane, olefin,
halogen and heterocyclic ring is rapidly prepared under the conditions of
room temperature, opening and neutrality, the catalyst is MBrx (M is Fe < 2 + >, Fe < 3 + >, Ce < 3 + > and the like, x is 2-3), and the only oxidant is H2O2. According to the present invention, the wide substrate synthesis and the amplification preparation of the [1, 2]
thiazine derivative using H2O2 as the
oxidizing agent are achieved for the first time, the catalytic reaction is green and sustainable, and the use of the expensive and complex catalyst is avoided. The by-product is H2O, and the problems of
environmental destruction, low yield and the like caused by catalytic reaction of many other strong oxidants are solved. The method is mild in reaction condition, simple in reaction process, high in yield, safe and
environmentally friendly, conforms to the
green chemistry concept, is wider in applicability, has wide development prospects and application prospects, and is expected to be widely applied to the fields of
organic synthesis, medicines, pesticides, probes and the like.