9 results about "Tocopherol succinate" patented technology

The antioxidant activity of alpha-tocopherol polyethylene glycol 1000 succinate (TPGS) and of alpha-tocopherol succinate (TS) has been examined in isolated hepatocytes and microsomal fractions from rat liver. Both TPGS and TS require esterase activity to yield free alpha-tocopherol and, hence, antioxidant activity. TPGS and TS consistently exerted a more effective antioxidant protection than an equivalent amount of directly-added free alpha-tocopherol. The low antioxidant efficiency of directly added free alpha-tocopherol in such water-based experimental systems as used here seems to be due to its extreme hydrophobicity. TPGS, on the other hand, is an extremely hydrophilic compound which is being examined as a useful source of alpha-tocopherol in certain clinical situations and is here shown to be a convenient and effective source for experimental studies into lipid peroxidation and antioxidant mechanisms.

The application discloses a Pseudomonas atacamensis STR8 and an application thereof, and belongs to the technical field of microorganisms. The strain is classified and named as Pseudomonas atacamensis STR8, and the preservation number is CCTCC NO: M 2025609. The hydrolysis circle HC value of the strain on a tributyrin plate is 2.78, and the lipase activity reaches 139.86 U / mL. The application also provides an application of the strain and a lipase produced by the strain in catalyzing hydrolysis of tocopherol succinate to prepare tocopherol. The strain STR8 is fermented to obtain a crude enzyme liquid, and the crude enzyme liquid is added into a reaction system containing the tocopherol succinate to perform a hydrolysis reaction. After 9 hours of reaction, the content of the tocopherol is increased by 750% compared with a control group. The strain and the method provided by the application have high catalytic efficiency, mild reaction conditions and environmental friendliness, and are suitable for green industrialized production of the tocopherol.

This invention discloses a strain of *Enterobacter cloacae* EC11 and its applications, belonging to the field of microbial technology. The strain is classified as *Enterobacter cloacae* EC11, with the accession number CCTCC NO:M 2025610. This strain exhibits a hydrolysis zone HC value of 3 on tributyrate agar plates and a lipase activity of 145.28 U / mL. This invention also provides the application of this strain and its produced lipase in the catalytic hydrolysis of tocopherol succinate to prepare tocopherol. The crude enzyme solution obtained by fermenting the lipase strain EC11 was added to a reaction system containing tocopherol succinate for hydrolysis. After 9 hours of reaction, the tocopherol content was increased by 725% compared to the control group. The strain and method provided by this invention have high catalytic efficiency, mild reaction conditions, and are environmentally friendly, making them suitable for the green industrial production of tocopherol.

The invention discloses Korean pseudomonas STR7 and application thereof, and belongs to the technical field of microorganisms. The strain is classified and named as Pseudomonas koreensis STR7, and the preservation number of the strain is CCTCC (China Center For Type Culture Collection) NO: M 2025608. The HC value of a hydrolysis circle of the strain on a tributyrin plate is 3, and the lipase activity reaches 136.81 U / mL. The invention also provides application of the strain and the lipase produced by the strain in preparation of tocopherol by catalyzing hydrolysis of tocopherol succinate. The strain STR7 is fermented to obtain crude enzyme liquid, the crude enzyme liquid is added into a reaction system containing tocopherol succinate for hydrolysis reaction, and after the reaction is performed for 9 hours, the content of tocopherol is increased by 865% compared with that of a control group. The strain and the method provided by the invention are high in catalytic efficiency, mild in reaction condition, environment-friendly and suitable for green industrial production of tocopherol.

The invention discloses a herbicide stabilizer and a preparation process thereof. The invention relates to a water-retaining agent, which is prepared from the following raw materials in percentage by mass: 20 to 25 percent of dichloropropene amine, 10 to 15 percent of beta-cyclodextrin-chitosan graft, 12 to 18 percent of sodium lignin sulfonate modified bentonite, 3 to 6 percent of alpha-tocopherol succinate, 4 to 8 percent of nano titanium dioxide coated UV-P, 1 to 3 percent of ethylene diamine tetraacetic acid, 2 to 5 percent of polyaspartic acid, 1 to 4 percent of sodium glycerophosphate and 8 to 11 percent of polyoxyethylene polyoxypropylene ether block copolymer. And the balance of modified white carbon black. The invention relates to the technical field of pesticides. According to the present invention, the dichloropropene amine is subjected to double anchoring, and the ultrasonic microwave synergistic inclusion process is combined to enhance the binding force of the dichloropropene amine and the carrier, such that the oxidation, the photolysis and the metal ion catalytic decomposition path of the dichloropropene amine are inhibited so as to further reduce the dichloropropene amine degradation rate, and the adaptation range of the dichloropropene amine can be improved; the function attenuation rate is also reduced, and the problem of insufficient dosage form compatibility caused by strong hydrophobicity of dichloropropene amine is effectively solved.

The invention provides a tanshinone IIA nano compound, a brain-targeted drug system, a drug preparation and application. The tanshinone IIA nano-composite comprises (1) tanshinone IIA and (2) a nano-carrier entrapping the tanshinone IIA, the nano-carrier comprises a chitosan derivative, and the chitosan derivative is connected with D-alpha-tocopherol succinate; wherein the nano carrier is connected with the tanshinone IIA through a cross-linking agent. The brain-targeted drug system provided by the invention comprises RVG29 and the tanshinone IIA nano compound. The tanshinone IIA nanocomposite and the brain-targeted drug system can be used for preparing drugs for preventing or treating neurodegenerative diseases.

This invention discloses a strain of *Pseudomonas fluorescens* STR2 and its applications, belonging to the field of microbial technology. The strain is classified as *Pseudomonas fluorescens* STR2, with accession number CCTCC NO: M 2025606. This strain exhibits a hydrolysis zone HC value of 4.23 on tributyrate plates and a lipase activity of 149.72 U / mL. This invention also provides the application of this strain and its produced lipase in the catalytic hydrolysis of tocopherol succinate to prepare tocopherol. The crude enzyme solution obtained by fermenting strain STR2 was added to a reaction system containing tocopherol succinate for hydrolysis. After 9 hours of reaction, the tocopherol content was increased by 700% compared to the control group. The strain and method provided by this invention have high catalytic efficiency, mild reaction conditions, and are environmentally friendly, making them suitable for the green industrial production of tocopherol.

This invention discloses a strain of Bacillus wiedmannii STR18 and its applications, belonging to the field of microbial technology. The strain is classified as Bacillus wiedmannii STR18, with accession number CCTCC NO:M 2025611. This strain exhibits a hydrolysis zone HC value of 3 on tributyrate plates and a lipase activity of 140 U / mL. This invention also provides the application of this strain and its produced lipase in the catalytic hydrolysis of tocopherol succinate to prepare tocopherol. The crude enzyme solution obtained by fermenting strain STR18 was added to a reaction system containing tocopherol succinate for hydrolysis. After 9 hours of reaction, the tocopherol content was increased by 800% compared to the control group. The strain and method provided by this invention have high catalytic efficiency, mild reaction conditions, and are environmentally friendly, making them suitable for the green industrial production of tocopherol.

This invention discloses a strain of *Enterobacter cloacae* STR5 and its applications, belonging to the field of microbial technology. The strain is classified as *Enterobacter cloacae* STR5, with accession number CCTCC NO: M 2025607. This strain exhibits a hydrolysis zone HC value of 3.95 on tributyrate plates and a lipase activity of 121.53 U / mL. This invention also provides the application of this strain and its produced lipase in the catalytic hydrolysis of tocopherol succinate to prepare tocopherol. The crude enzyme solution obtained by fermenting strain STR5 was added to a reaction system containing tocopherol succinate for hydrolysis. After 9 hours of reaction, the tocopherol content was increased by 700% compared to the control group. The strain and method provided by this invention have high catalytic efficiency, mild reaction conditions, and are environmentally friendly, making them suitable for the green industrial production of tocopherol.