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Embodiments of the present specification provide a GPU resource management method and device, the method is applied to a cloud side node, comprising: receiving a processing request sent by a user, analyzing the processing request, determining an object identifier and GPU resource demand information corresponding to the processing request; in the case of determining that the container responds to the processing request according to the object identifier, determining a target edge node from the edge node cluster based on the idle container GPU resource information of each edge node in the edge node group according to the GPU resource demand information, and in the case of determining that the virtual machine responds to the processing request according to the object identifier, determining a target edge node from the edge node group based on the idle virtual machine GPU resource information of each edge node according to the GPU resource demand information, wherein the edge node group contains at least two edge nodes, and each edge node is configured with at least two GPUs; sending the object identifier and the GPU resource demand information to the target edge node.