4results about How to "Improve membrane permeability" patented technology

The invention discloses a graphene oxide nanofiltration membrane constructed by a charge compensation cross-linking agent and a preparation method of the graphene oxide nanofiltration membrane. The nanofiltration membrane is prepared by the following steps: cross-linking the charge compensation cross-linking agent and graphene oxide nanosheets, diluting the cross-linked nanosheet dispersion liquid, and carrying out ultrasonic treatment and suction filtration. The invention also discloses a preparation method and application of the nanofiltration membrane. According to the preparation method, a macroporous polymer membrane is taken as a supporting layer, and a charge compensation cross-linked graphene oxide nanosheet is loaded on the supporting layer in a vacuum filtration manner, so that the charge compensation cross-linked graphene oxide nanofiltration membrane is prepared. The method is simple and convenient to operate, and the interlayer electronegativity is compensated while the interlayer spacing of the nanofiltration membrane is stabilized by adopting a charge compensation cross-linking agent to be cross-linked with the graphene oxide nanosheets, so that the selectivity of the membrane is improved; meanwhile, the cross-linking agent with a sulfonic acid group improves the permeability of the cross-linked graphene oxide nanofiltration membrane due to the hydrophilicity of the sulfonic acid group.

The invention relates to a monatomic nanofiber catalytic membrane with gradient distribution of catalysts as well as a preparation method and application of the monatomic nanofiber catalytic membrane, and belongs to the technical field of membrane separation-catalytic coupling and sewage treatment. The technical problems that in the prior art, a catalytic membrane cannot effectively treat high-salinity wastewater, and the utilization rate of a catalyst and active oxygen is low are solved. The monatomic nanofiber catalytic membrane comprises a nanofiber base membrane and a metal-C3N4 monatomic catalyst which is distributed on the surface of the nanofiber base membrane in a gradient manner. The preparation method comprises the following steps: firstly, synthesizing a metal-C3N4 monatomic catalyst; then preparing spinning solutions of metal-C3N4 monatomic catalysts with different concentrations; finally, gradient spinning, hole forming and drying are conducted, the monatomic nanofiber catalytic membrane is obtained, stable loading of a monatomic catalyst in the catalytic membrane is achieved, gradient distribution of the singlet oxygen concentration of a hole channel is achieved, and the catalytic degradation efficiency of the nanofiber catalytic membrane on organic pollutant molecules is greatly improved.

An aromatic heterocyclic compound, and a pharmaceutical composition and an application thereof. Specifically disclosed are a compound as represented by formula I-A, a stereoisomer thereof, a diastereoisomer thereof, or a pharmaceutically acceptable salt of any one of the described substances, or a crystalline form or a solvate of any one of the described substances. The aromatic heterocyclic compound is novel in structure, and has good CDK7 inhibitory activity and good selectivity.

This invention relates to novel, highly efficient subcellular targeted drug delivery conjugates, their preparation methods, compositions, and uses. The conjugates include a carrier module, a controlled-release module, a connecting arm, a subcellular targeting module, and a pharmacodynamic module. The conjugates of this invention can be used in applications such as highly efficient photodynamic therapy, chemotherapy, and immunotherapy targeting organelles, or in combination thereof.