An indwelling thrombolytic catheter

Abstract

The present application relates to the field of thrombolytic catheter, in particular, to a kind of indwelling type blood-passable thrombolytic catheter, including catheter, the inside of the pipe wall of the catheter is provided with medicine cavity, the catheter is provided with medicine spraying hole being communicated with the medicine cavity, the catheter is equipped with air bag, the air bag is equipped with at least two, the air bag is spaced apart, the medicine spraying hole is located between the adjacent two air bags, the catheter is connected with the medicine delivery tube for sending medicine to the inside of the medicine cavity, the air bag is connected with air pipe, further including sheath tube, one end of the sheath tube is connected with hemostasis valve, the other end of the sheath tube is an opening;The present application aims at overcoming the deficiencies of prior art and providing a kind of indwelling type blood-passable thrombolytic catheter, when local thrombolysis is carried out to blood vessel again, it does not affect the blood transport inside blood vessel, avoid the necrosis of the inner wall cells of blood vessel due to hypoxia.

Description

[0001] CROSS-REFERENCE TO RELATED APPLICATIONS

[0002] The present application is based on the divisional application of the application No. CN202211007597.3, the application date of which is August 22, 2022, and the title of which is: A thrombolytic catheter with blood passage. TECHNICAL FIELD

[0003] The present application relates to the field of thrombolytic catheters, in particular, to a left-in thrombolytic catheter with blood passage. BACKGROUND

[0004] Vascular embolism is a common condition in cardiovascular diseases, which can lead to insufficient blood supply in the patient's body and even death. Therefore, it is necessary to dissolve or remove the thrombus in the patient's blood vessel.

[0005] In the prior art, mechanical thrombectomy or drug thrombolysis is usually used. The former has the problem that the thrombus will be broken and dispersed during the thrombectomy process, and the small thrombus will continue to block the blood vessel. The latter can use systemic or local drug administration for thrombolysis. During systemic drug administration, the drug can cause certain damage to the blood vessel, which can cause bleeding and complications. Local drug administration requires the use of a catheter with a balloon to block the blood vessel and perform local thrombolysis. Since one end of the catheter is located outside the blood vessel and the other end is located inside the blood vessel, the blood passage inside the blood vessel will be cut off after the balloon blocks the blood vessel, and the blood supply in the blood vessel will be interrupted. If the thrombolysis time is too long, the cells on the inner wall of the blood vessel will die due to lack of oxygen, which can cause damage to the blood vessel function of the patient. Therefore, how to design a left-in thrombolytic catheter with blood passage, which can perform local thrombolysis on the blood vessel without affecting the blood transport inside the blood vessel and avoiding the death of the cells on the inner wall of the blood vessel due to lack of oxygen, has become a technical problem to be solved. SUMMARY

[0006] Therefore, the present application aims to overcome the shortcomings of the prior art and provide a left-in thrombolytic catheter with blood passage, which can perform local thrombolysis on the blood vessel without affecting the blood transport inside the blood vessel and avoiding the death of the cells on the inner wall of the blood vessel due to lack of oxygen.

[0007] In order to solve the above technical problems, the technical solution of the present application is as follows:

[0008] The application discloses a catheter for thrombolysis, which comprises a catheter, a medicine cavity is formed in the inner wall of the catheter, a medicine injection hole is formed in the catheter and is communicated with the medicine cavity, air bags are arranged on the catheter, the air bags are arranged at intervals, the medicine injection hole is arranged between two adjacent air bags, a medicine delivery pipe is connected with the medicine cavity, an air delivery pipe is connected with the air bags, a sheath pipe is arranged, one end of the sheath pipe is connected with a hemostatic valve, the other end of the sheath pipe is an opening, the sheath pipe is used for containing the catheter, a first driving assembly is arranged in the sheath pipe and is used for driving the catheter to be separated from the opening of the sheath pipe, and the free end of the air delivery pipe and the free end of the medicine delivery pipe are arranged outside the hemostatic valve.

[0009] The catheter is arranged in the sheath pipe, the sheath pipe is inserted into the blood vessel of a patient from the opening of the blood vessel and is moved to the thrombus, and the first driving assembly drives the catheter to be separated from the opening of the sheath pipe.

[0010] The air bags are inflated by the air delivery pipe, the sheath pipe is pulled out of the blood vessel of the patient when the air bags are inflated and press against the inner wall of the blood vessel, and the catheter is arranged in the blood vessel of the patient.

[0011] Compared with the prior art, the application has the following advantages:

[0012] In use, the catheter is arranged in the sheath pipe, the free end of the air delivery pipe and the free end of the medicine delivery pipe are arranged outside the hemostatic valve, the sheath pipe is inserted into the blood vessel of a patient from the opening of the blood vessel, the sheath pipe is moved to the thrombus, the first driving assembly drives the catheter to be separated from the opening of the sheath pipe, and the catheter passes through the thrombus.

[0013] The air bags are inflated by the air delivery pipe, the sheath pipe is pulled out of the blood vessel of the patient when the air bags are inflated and press against the inner wall of the blood vessel, and the catheter is arranged in the blood vessel of the patient, thrombolytic liquid is filled into the medicine cavity through the medicine delivery pipe, the thrombolytic liquid flows through the medicine cavity and is discharged into the blood vessel through the medicine injection hole, the thrombolytic liquid dissolves the thrombus in the blood vessel, in the process, blood passes through the inner cavity of the catheter, the catheter does not affect the blood transportation in the blood vessel, and thus, the cells of the inner wall of the blood vessel are prevented from being necrotic due to oxygen deficiency.

[0014] After the thrombolysis is completed, the air in the air bags is discharged through the air delivery pipe, the air bags no longer press against the inner wall of the blood vessel, and the catheter is pulled out of the blood vessel through the air delivery pipe or the medicine delivery pipe.

[0015] Preferably, the first driving assembly comprises a spring arranged in the sheath pipe, and the spring is used for providing a driving force for the catheter to be separated from the opening of the sheath pipe.

[0016] Preferably, the inside of the sheath is also provided with a push seat for pushing the catheter, the push seat is in sliding connection with the sheath, and one end of the push seat is fixedly connected with the spring.

[0017] Preferably, the middle part of the push seat is provided with a first through hole for the air feeding tube and the medicine feeding tube to pass through.

[0018] Preferably, the opening of the sheath is provided with flexible plates, the flexible plates are fixedly connected with the sheath, the inside of the connection part of the flexible plates and the sheath is embedded with a reed, the flexible plates are arranged in an annular array, the reed is used for supporting the free end of the flexible plates to expand radially, and the free end of the flexible plates is connected with a second driving assembly for driving the free end of the flexible plates to gather.

[0019] Preferably, the second driving assembly comprises a pull rope, one end of the pull rope is fixedly connected with the free end of the flexible plate, and the other end of the pull rope passes through the sheath and penetrates through the hemostasis valve.

[0020] Preferably, the pull rope is connected with a pull ring, and the pull ring is fixedly connected with the pull rope.

[0021] Preferably, the hemostasis valve comprises an opening and closing cylinder, the inside of the opening and closing cylinder is provided with a stopper and an elastic rubber sleeve, the stopper is provided with a second through hole, the elastic rubber sleeve is provided with a third through hole, the elastic rubber sleeve is connected with a push rod assembly, the opening and closing cylinder is provided with a suction tube, one end of the suction tube is in communication with the inner cavity of the opening and closing cylinder, the elastic rubber sleeve is divided into an opening state and a closed state, in the opening state, the sheath, the second through hole, the third through hole and the inner cavity of the opening and closing cylinder are in communication, with the abutting pressure of the push rod assembly on the elastic rubber sleeve, the elastic rubber sleeve is deformed and extruded into the inside of the second through hole, and the part of the elastic rubber sleeve in the inside of the second through hole closes the second through hole to isolate the sheath and the inner cavity of the opening and closing cylinder.

[0022] Preferably, the push rod assembly comprises an opening and closing shaft, one end of the opening and closing shaft is in abutting pressure with the elastic rubber sleeve, and the other end of the opening and closing shaft is in screw connection with the opening and closing cylinder.

[0023] Preferably, at least one end of the medicine feeding tube is provided with a bevel. BRIEF DESCRIPTION OF DRAWINGS

[0024] Figure 1 It is a structural schematic view of the present application;

[0025] Figure 2 It is a sectional view schematic view of the present application;

[0026] Figure 3 It is Figure 2 the enlarged schematic view of A;

[0027] Figure 4 is a sectional view of the sheath tube;

[0028] Figure 5 is an enlarged view of B in Figure 4

[0029] Figure 6 is a sectional view of the catheter.

[0030] The drawings show: 10, catheter; 11, medicine cavity; 12, medicine spraying hole; 13, air bag; 14, air feeding tube; 15, medicine feeding tube; 16, bevel; 20, sheath tube; 21, flexible plate; 22, spring leaf; 23, pull rope; 24, pull ring; 25, push seat; 26, first through hole; 27, spring; 30, stop block; 31, second through hole; 32, elastic rubber sleeve; 33, third through hole; 34, opening and closing shaft; 35, opening and closing cylinder; 36, fourth through hole; 37, suction tube. DETAILED DESCRIPTION

[0031] The specific embodiments of the present application are further described in detail below with reference to the accompanying drawings, so that the technical scheme of the present application is easier to understand and master.

[0032] Example One:

[0033] Referring to Figures 1 to 6 , the present embodiment provides a blood thrombolysis catheter, which can perform local thrombolysis on blood vessels without affecting the blood transportation inside the blood vessels, and avoids the necrosis of the cells on the inner wall of the blood vessels due to hypoxia.

[0034] A blood thrombolysis catheter, comprising a catheter 10, a medicine cavity 11 is formed in the inner wall of the catheter 10, a medicine spraying hole 12 is formed in the catheter 10 and is in communication with the medicine cavity 11, an air bag 13 is arranged on the catheter 10, the air bag 13 is provided in at least two, the air bags 13 are arranged at intervals, the medicine spraying hole 12 is located between the adjacent two air bags 13, the catheter 10 is connected with a medicine feeding tube 15 for feeding medicine into the medicine cavity 11, the air bag 13 is connected with an air feeding tube 14, further comprising a sheath tube 20, one end of the sheath tube 20 is connected with a hemostatic valve, the other end of the sheath tube 20 is an opening, the sheath tube 20 is used for accommodating the catheter 10, the inner part of the sheath tube 20 is further provided with a first driving assembly for driving the catheter 10 to be separated from the opening of the sheath tube 20, the free end of the air feeding tube 14 and the free end of the medicine feeding tube 15 both extend to the outside of the hemostatic valve.

[0035] ​In use, the catheter 10 is placed inside the sheath tube 20, the free end of the air delivery tube 14 and the free end of the medicine delivery tube 15 are penetrated through the hemostatic valve, the sheath tube 20 is inserted into the patient's blood vessel from the opening of the patient's blood vessel, the sheath tube 20 is moved so that the opening of the sheath tube 20 is moved to the thrombus, the first driving assembly drives the catheter 10 to be pulled out of the opening of the sheath tube 20, so that the catheter 10 passes through the thrombus from the middle part of the thrombus;

[0036] The air inside the air bag 13 is filled through the air delivery tube 14, when the air bag 13 is inflated and pressed against the inner wall of the blood vessel, the sheath tube 20 is pulled out of the patient's blood vessel, the catheter 10 is left in the patient's blood vessel, the thrombolytic drug solution is filled into the medicine cavity 11 through the medicine delivery tube 15, the drug solution flows through the medicine cavity 11 and is discharged to the inside of the blood vessel through the medicine injection hole 12, and the drug solution dissolves the thrombus in the blood vessel. In this process, the blood passes through the inner cavity of the catheter 10, and the catheter 10 does not affect the blood transport in the blood vessel, thereby avoiding the necrosis of the cells on the inner wall of the blood vessel due to lack of oxygen;

[0037] After the thrombolysis is completed, the air inside the air bag 13 is discharged through the air delivery tube 14, the air bag 13 is no longer pressed against the inner wall of the blood vessel, and the catheter 10 is pulled out of the inside of the blood vessel through the air delivery tube 14 or the medicine delivery tube 15.

[0038] As shown in Figure 2 , Figure 3 and Figure 4 , in order to drive the catheter 10 to be pulled out of the inside of the sheath tube 20, the first driving assembly comprises a spring 27 arranged inside the sheath tube 20, the spring 27 is used to provide a driving force for the catheter 10 to be pulled out of the opening of the sheath tube 20, the inside of the sheath tube 20 is further provided with a push seat 25, the push seat 25 is in sliding connection with the sheath tube 20, one end of the push seat 25 is fixedly connected with the spring 27, the push seat 25 is used to push the catheter 10, and the middle part of the push seat 25 is provided with a first through hole 26 for the air delivery tube 14 and the medicine delivery tube 15 to pass through.

[0039] In use, the catheter 10 is pulled into the inside of the sheath tube 20 through the air delivery tube 14 or the medicine delivery tube 15, the spring 27 is compressed, when it is needed to push the catheter 10 out of the inside of the sheath tube 20, the air delivery tube 14 and the medicine delivery tube 15 are released, the spring 27 is reset, and the catheter 10 is pulled out of the inside of the sheath tube 20 under the elastic force of the spring 27.

[0040] As shown in Figure 1 , Figure 2 , Figure 3 and Figure 4As shown, in order to weaken the influence of the catheter 10 on the blood supply as much as possible, the diameter of the catheter 10 is increased as much as possible because the blood vessels are thin; and in order to facilitate the entry of the sheath tube 20 into the blood vessels without affecting the entry of the catheter 10 into the sheath tube 20, the opening of the sheath tube 20 is provided with flexible plates 21, the flexible plates 21 are fixedly connected with the sheath tube 20, the inside of the connection between the flexible plates 21 and the sheath tube 20 is embedded with reed 22, the flexible plates 21 are arranged in an annular array, the free end of the flexible plate 21 is radially expanded, the free end of the flexible plate 21 is connected with a pull rope 23 for driving the free end of the flexible plate 21 to gather, one end of the pull rope 23 is fixedly connected with the free end of the flexible plate 21, the other end of the pull rope 23 passes through the sheath tube 20 and penetrates the hemostatic valve, the pull rope 23 is connected with a pull ring 24, and the pull ring 24 is fixedly connected with the pull rope 23.

[0041] In use: the flexible plates 21 are gathered by pulling the pull ring 24 and the pull rope 23, and the reed 22 is compressed, when the sheath tube 20 enters the blood vessels, the gathered flexible plates 21 have a small diameter at the end, which can facilitate the entry of the sheath tube 20 into the blood vessels and avoid scratching the inner wall of the blood vessels when the sheath tube 20 enters the blood vessels, when the sheath tube 20 reaches the thrombus, the pull ring 24 is released, the reed 22 is reset, the flexible plate 21 is reset under the action of the reed 22, the free end of the flexible plate 21 is radially expanded, the spring 27 drives the catheter 10 to come out of the inside of the sheath tube 20 through the push seat 25, the sheath tube 20 comes out of the inside of the blood vessels, and the catheter 10 is left in the inside of the blood vessels for thrombolysis;

[0042] When the catheter 10 needs to be recovered, the catheter 10 can be directly pulled out of the inside of the blood vessels through the gas delivery tube 14 or the medicine delivery tube 15; however, since the diameter of the catheter 10 is smaller than the diameter of the blood vessels, the catheter 10 may be inclined in the blood vessels when directly pulled out, which may scratch the inner wall of the blood vessels during movement;

[0043] In order to avoid scratching the inner wall of the blood vessels by the catheter 10, when the catheter 10 needs to be taken out, the flexible plates 21 are gathered by pulling the pull ring 24 and the pull rope 23, and the reed 22 is compressed, when the sheath tube 20 enters the blood vessels, the gathered flexible plates 21 have a small diameter at the end, which can facilitate the entry of the sheath tube 20 into the blood vessels and avoid scratching the inner wall of the blood vessels when the sheath tube 20 enters the blood vessels, when the sheath tube 20 reaches the position of the catheter 10, the pull ring 24 is released, the reed 22 is reset, the flexible plate 21 is reset under the action of the reed 22, the free end of the flexible plate 21 is radially expanded, and the catheter 10 is pulled into the inside of the sheath tube 20 through the gas delivery tube 14 or the medicine delivery tube 15;

[0044] In this process, since the free ends of the plurality of flexible plates 21 are radially expanded, under the guidance of the plurality of flexible plates 21, the catheter 10 can smoothly enter the inside of the sheath tube 20.

[0045] In combination with Figure 2 , Figure 4 and Figure 5 shown, in order to avoid blood spraying along the sheath tube 20, and facilitate the discharge of dissolved thrombus, the hemostatic valve comprises an opening and closing cylinder 35, the inside of the opening and closing cylinder 35 is provided with a stop block 30 and an elastic rubber sleeve 32, the stop block 30 is provided with a second through hole 31, the elastic rubber sleeve 32 is provided with a third through hole 33, the elastic rubber sleeve 32 is connected with an opening and closing shaft 34, one end of the opening and closing shaft 34 abuts against the elastic rubber sleeve 32, the other end of the opening and closing shaft 34 is threadedly connected with the opening and closing cylinder 35, the opening and closing cylinder 35 is provided with a suction pipe 37, one end of the suction pipe 37 communicates with the inner cavity of the opening and closing cylinder 35, the elastic rubber sleeve 32 is divided into an opening state and a closed state, in the opening state, the sheath tube 20, the second through hole 31, the third through hole 33 and the inner cavity of the opening and closing cylinder 35 are communicated, with the rotation of the opening and closing shaft 34, the opening and closing shaft 34 moves relative to the opening and closing cylinder 35, the opening and closing shaft 34 abuts against the elastic rubber sleeve 32, the elastic rubber sleeve 32 deforms and extrudes into the inside of the second through hole 31, the part of the elastic rubber sleeve 32 entering the inside of the second through hole 31 closes the second through hole 31 and isolates the sheath tube 20 from the inner cavity of the opening and closing cylinder 35.

[0046] In use: through the sheath tube 20, the catheter 10 is sent into the inside of the blood vessel for thrombolysis, the opening and closing shaft 34 is rotated, the opening and closing shaft 34 moves relative to the opening and closing cylinder 35, the opening and closing shaft 34 abuts against the elastic rubber sleeve 32, the elastic rubber sleeve 32 deforms and extrudes into the inside of the second through hole 31, the part of the elastic rubber sleeve 32 entering the inside of the second through hole 31 closes the second through hole 31 and isolates the sheath tube 20 from the inner cavity of the opening and closing cylinder 35, avoiding blood spraying through the sheath tube 20, through the gas sending pipe 14, the gas is filled into the inside of the air bag 13 to place the catheter 10 in the blood vessel; the opening and closing shaft 34 is reversed, the opening and closing shaft 34 reversely moves relative to the opening and closing cylinder 35, the degree of the opening and closing shaft 34 abutting against the elastic rubber sleeve 32 is weakened, until the elastic rubber sleeve 32 resets and extrudes into the inside of the second through hole 31, the sheath tube 20, the second through hole 31, the third through hole 33 and the inner cavity of the opening and closing cylinder 35 are communicated, at this time, the sheath tube 20 is pulled out from the inside of the blood vessel;

[0047] After the catheter 10 completes thrombolysis in the inside of the blood vessel, the sheath tube 20 is inserted into the blood vessel again to recover the catheter 10, at this time, the residue left in the inside of the blood vessel after thrombolysis is pulled out through the suction pipe 37.

[0048] In order to facilitate the catheter 10 into the inside of the sheath 20, at least one end of the gas delivery tube 15 is provided with a bevel 16.

[0049] Embodiment two:

[0050] The difference between this embodiment and embodiment one is the first driving assembly;

[0051] In order to drive the catheter 10 to come out from the inside of the sheath 20, at least one of the gas delivery tube 14 or the medicine delivery tube 15 is made of a flexible material to ensure that when the gas delivery tube 14 or the medicine delivery tube 15 is moved, the gas delivery tube 14 or the gas delivery tube 14 can directly push the catheter 10 to come out from the inside of the sheath 20.

[0052] In use: push the gas delivery tube 14 or the medicine delivery tube 15, the gas delivery tube 14 or the gas delivery tube 14 pushes the catheter 10 to come out from the inside of the sheath 20, pull the gas delivery tube 14 or the medicine delivery tube 15, the gas delivery tube 14 or the gas delivery tube 14 drives the catheter 10 to enter the inside of the sheath 20.

[0053] The above is only a typical example of the present application, in addition to this, the present application can have other various specific embodiments, any technical solution formed by equivalent replacement or equivalent transformation, falls within the scope of the present application.

Claims

1. An indwelling thrombolytic catheter, comprising a catheter (10), wherein a drug-dissolving cavity (11) is formed inside the wall of the catheter (10), a drug-dispensing orifice (12) communicating with the drug-dissolving cavity (11) is formed on the catheter (10), and an air bag (13) is provided on the catheter (10), characterized in that, At least two airbags (13) are provided, and the airbags (13) are spaced apart. The spray nozzle (12) is located between two adjacent airbags (13). The conduit (10) is connected to a delivery tube (15) for delivering medicine into the medicine chamber (11). The airbag (13) is connected to an air delivery tube (14). It also includes a sheath (20). One end of the sheath (20) is connected to a hemostatic valve. The other end of the sheath (20) is an opening. The sheath (20) is used to accommodate the conduit (10). The interior of the sheath (20) is also provided with a first driving component for driving the conduit (10) to disengage from the opening of the sheath (20). The free ends of the air delivery tube (14) and the free ends of the delivery tube (15) both extend to the outside of the hemostatic valve. The catheter (10) is placed inside the sheath (20), the sheath (20) is inserted into the patient's blood vessel from the opening of the blood vessel and the opening of the sheath (20) is moved to the thrombus, and the first drive assembly drives the catheter (10) to dislodge from the opening of the sheath (20). Inflate the balloon (13) through the air delivery tube (14). When the balloon (13) expands and presses against the inner wall of the blood vessel, the sheath (20) is pulled out of the patient's blood vessel, and the catheter (10) is left inside the patient's blood vessel. The first drive assembly includes a spring (27) disposed inside the sheath (20), the spring (27) being used to provide a driving force to the catheter (10) to disengage the catheter (10) from the opening of the sheath (20); The opening of the sheath (20) is provided with a flexible plate (21), and the flexible plates (21) are all fixedly connected to the sheath (20). A spring (22) is embedded inside the connection between the flexible plate (21) and the sheath (20). Multiple flexible plates (21) are arranged in a ring array. The spring (22) is used to support the free end of the flexible plate (21) to spread radially. The free end of the flexible plate (21) is connected to a second driving component for driving the free ends of multiple flexible plates (21) to converge. The second drive assembly includes a pull cord (23), one end of which is fixedly connected to the free end of the flexible plate (21), and the other end of which passes through the sheath (20) and through the hemostatic valve.

2. The indwelling thrombolytic catheter according to claim 1, characterized in that, The sheath (20) is further provided with a pusher (25) for pushing the catheter (10). The pusher (25) is slidably connected to the sheath (20), and the pusher (25) is fixedly connected to one end of the spring (27).

3. The indwelling thrombolytic catheter according to claim 2, characterized in that, The push base (25) has a first through hole (26) in the middle for the air delivery pipe (14) and the medicine delivery pipe (15) to pass through.

4. The indwelling thrombolytic catheter according to claim 1, characterized in that, The pull rope (23) is connected to a pull ring (24), and the pull ring (24) is fixedly connected to the pull rope (23).

5. A permissible thrombolytic catheter according to any one of claims 1 to 4, characterized in that, The hemostatic valve includes an opening and closing cylinder (35), inside which are provided a stop block (30) and an elastic sleeve (32). The stop block (30) has a second through hole (31), and the elastic sleeve (32) has a third through hole (33). The elastic sleeve (32) is connected to a push rod assembly. The opening and closing cylinder (35) is provided with a suction tube (37), one end of which communicates with the inner cavity of the opening and closing cylinder (35). The elastic sleeve (32) is divided into an open state and a closed state. In the closed state and the open state, the sheath (20), the second through hole (31), the third through hole (33) are connected to the inner cavity of the opening and closing cylinder (35). As the push rod assembly presses against the elastic sleeve (32), the elastic sleeve (32) deforms and is squeezed into the interior of the second through hole (31). The part of the elastic sleeve (32) that enters the interior of the second through hole (31) seals the second through hole (31) and isolates the sheath (20) from the inner cavity of the opening and closing cylinder (35).

6. The indwelling thrombolytic catheter according to claim 5, characterized in that, The push rod assembly includes an opening and closing shaft (34), one end of which abuts against the elastic sleeve (32), and the other end of which is threadedly connected to the opening and closing cylinder (35).

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