Line-scanning based super-resolution imaging method and device

Through the super-resolution imaging method and device of line scanning, the progressive scanning technology of excitation light of various linear structures is used to solve the problem of moving the target area in live animal imaging, and efficient super-resolution imaging is achieved, which is suitable for the imaging needs of live animal.

CN116195977BActive Publication Date: 2025-07-25CENT FOR EXCELLENCE IN BRAIN SCI & INTELLIGENCE TECH CHINESE ACAD OF SCI
1 Cites 4 Cited by

Patent Information

Application Number
CN202310207189.0
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-03-06
Publication Date
2025-07-25
Estimated Expiration
2043-03-06

AI Technical Summary

Technical Problem

Existing super-resolution imaging techniques are difficult to tolerate the movement of the target area during the imaging of live animals, especially the limb movement of live animals in a awake and mobile state, resulting in imaging failure.

Method used

Using a super-resolution imaging method and device based on line scanning, single scan imaging is achieved by providing a variety of linear structure excitation light, each excitation light has a different illumination mode, and scanning the target area progressively in a single direction, detecting the response light of each row, and realizing single scan imaging.

Benefits of technology

It realizes a high tolerance for the target area during the imaging of live animals, improves the imaging speed, and can reconstruct super-resolution images while the target area is moved, which is suitable for the imaging needs of live animals.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The present disclosure relates to a line-scanning based super-resolution imaging method and apparatus. A line-scanning based super-resolution imaging method includes: providing a plurality of line-type structured excitation lights, each of the plurality of line-type structured excitation lights having a different illumination pattern; illuminating a target area in a line-by-line scanning manner along a single first direction while switching the plurality of line-type structured excitation lights, such that each row in the target area is illuminated by a corresponding one of the plurality of line-type structured excitation lights; and detecting response light generated by each row in the target area in response to being illuminated by the corresponding one of the plurality of line-type structured excitation lights.
Need to check novelty before this filing date? Find Prior Art