Microwave ablation catheter and microwave ablation system

Abstract

The present invention relates to a microwave ablation catheter and a microwave ablation system, and to the field of ablation technology. The microwave ablation catheter of the present invention comprises a main body tube, an inner tube extending in the main body tube, and a coaxial cable extending in the inner tube. A microwave antenna radiation unit is arranged at the proximal end of the main body tube, and the microwave antenna radiation unit is connected to the coaxial cable, wherein an electromagnetic sensor is also arranged inside the microwave antenna radiation unit and / or at the distal end side of the microwave antenna radiation unit. When the distal end of the microwave ablation catheter enters the electromagnetic field, the electromagnetic sensor therein will generate a potential difference. By collecting the potential difference, the position and posture of the electromagnetic sensor in the magnetic field can be calculated, and the position and direction of the distal end of the microwave ablation catheter in the patient's body can be known, thereby providing navigation introduction for the microwave ablation catheter when it enters the internal organs of the human body through an endoscope or a natural cavity, and the relative position of the microwave ablation catheter and the lesion can be known, thereby improving the accuracy of the operation.

Description

Technical Field

[0001] The present invention relates to the technical field of ablation, and in particular to a microwave ablation catheter and a microwave ablation system. Background Art

[0002] In recent years, microwave ablation can be applied to treat a variety of lesions, for example, nodules in different organs such as the liver, brain, heart, lungs and kidneys. When a nodule is found in the lungs, multiple factors are considered in the process of diagnosis. For example, a biopsy tool can be used under CT guidance to obtain a biopsy of the nodule. If the biopsy reveals that the nodule is malignant, the nodule can be ablated. In this case, microwave ablation, which usually involves transmitting microwave energy to a percutaneous puncture needle, is used to ablate the nodule or treat varicose veins. Existing microwave ablation catheters cannot know the position and direction of the distal end of the puncture in the patient's body during puncture, and therefore cannot provide guidance for the operator's puncture operation. Summary of the invention

[0003] The present invention provides a microwave ablation catheter and a microwave ablation system, which are used to solve at least one of the above-mentioned technical problems.

[0004] According to a first aspect of the present invention, the present invention provides a microwave ablation catheter, comprising a main body tube, an inner tube extending in the main body tube, and a coaxial cable extending in the inner tube, wherein a microwave antenna radiation unit is disposed at a distal end of the main body tube, and the microwave antenna radiation unit is connected to the coaxial cable;

[0005] Wherein, an electromagnetic sensor is also arranged in the microwave antenna radiation unit and / or in the main body tube.

[0006] In one embodiment, the microwave antenna radiation unit includes a microwave antenna radiation portion located at the distal end of the main body tube, a first cavity is provided inside the microwave antenna radiation portion and / or a second cavity is provided at the distal end of the microwave antenna radiation portion;

[0007] The electromagnetic sensor is disposed in the first cavity and / or the second cavity.

[0008] In one embodiment, the microwave antenna radiation unit further comprises a microwave antenna connection portion conductively connected to the microwave antenna radiation portion, the microwave antenna connection portion extends into the first cavity and is connected to the coaxial cable;

[0009] The electromagnetic sensor includes at least one electromagnetic sensor coil, and the at least one electromagnetic sensor coil is wound around the portion of the microwave antenna connecting portion located in the first cavity.

[0010] In one embodiment, the first end of the microwave antenna connecting portion extends into the first cavity and is connected to the coaxial cable, and the second end of the microwave antenna connecting portion is located in the second cavity;

[0011] The electromagnetic sensor includes at least one electromagnetic sensor coil arranged in the second cavity, and the at least one electromagnetic sensor coil is spaced apart from the second end of the microwave antenna connecting part.

[0012] In one embodiment, the electromagnetic sensor is connected to a wire, which is located between the inner tube and the coaxial cable and extends from the distal end to the proximal end of the coaxial cable.

[0013] In one embodiment, a puncture portion is provided on the distal end side of the microwave antenna radiation unit, or a puncture portion is integrated on the distal end side of the microwave antenna radiation unit.

[0014] In one embodiment, one or more light sources are further disposed between the main tube and the inner tube.

[0015] In one embodiment, an isolation element is connected between the distal end side of the main body tube and the proximal end side of the microwave antenna radiation unit, and the main body tube, the isolation element and the microwave antenna radiation unit are overlapped and connected.

[0016] In one embodiment, a traction mechanism is provided in the main body tube, and the traction mechanism is configured to be able to bend one or more of the main body tube, the isolation element, and the microwave antenna radiation unit.

[0017] In one embodiment, a choke element is further included, wherein the choke element is located in a coolant inlet channel defined by the inner tube and the coaxial cable and / or a coolant return channel defined by the main tube and the inner tube;

[0018] Wherein, the choke element is constructed as a metal coil extending in a spiral form on the outer wall of the inner tube and / or a metal sleeve connected to the proximal end of the main body tube.

[0019] In one embodiment, it also includes an outer sheath tube, which covers the outside of the main tube and the microwave antenna radiation unit. The outer sheath tube is constructed to be movable relative to the main tube to adjust the length of the main tube and the microwave antenna radiation unit covered by the outer sheath tube.

[0020] According to a second aspect of the present invention, the present invention provides a microwave ablation system, comprising the above-mentioned microwave ablation catheter and a handle mechanism, wherein the proximal end of the microwave ablation catheter extends into the handle mechanism.

[0021] In one embodiment, it also includes an inlet tube and a return tube extending into the handle mechanism, the inlet tube is in fluid communication with the coolant inlet channel defined by the inner tube and the coaxial cable, and the return tube is in fluid communication with the coolant return channel defined by the main tube and the inner tube.

[0022] In one embodiment, the handle mechanism includes a handle housing, an amplifier, a controller, and a microwave signal generator, wherein the amplifier is electrically connected to the controller and the electromagnetic sensor, respectively, and the microwave signal generator is connected to the proximal end of the coaxial cable.

[0023] In one embodiment, the handle housing is further provided with an adjusting device and a locking mechanism connected to the adjusting device, the adjusting device is connected to a traction mechanism in the main body tube, and the adjusting device drives the traction mechanism by pushing, pulling and / or rotating.

[0024] In one embodiment, the handle mechanism includes a pushing handle, an adjusting mechanism connected to the pushing handle, and a Luer connector connected to the adjusting mechanism, and the proximal end of the microwave ablation catheter is connected to the adjusting mechanism.

[0025] Compared with the prior art, the advantage of the present invention is that when the distal end of the microwave ablation catheter enters the electromagnetic field, the electromagnetic sensor therein will generate a potential difference. By collecting the potential difference, the position and posture of the electromagnetic sensor in the magnetic field can be calculated, and the position and direction of the distal end of the microwave ablation catheter in the patient's body can be known, thereby providing navigation guidance when the microwave ablation catheter enters the internal organs of the human body through an endoscope or a natural cavity, and the relative position of the microwave ablation catheter and the lesion can be known, thereby improving the accuracy of the operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Hereinafter, the present invention will be described in more detail based on embodiments and with reference to the accompanying drawings.

[0027] Figure 1a is a cross-sectional view of the flexible microwave ablation catheter in Example 1 of the present invention, wherein no choke element is provided;

[0028] Figure 1b is a cross-sectional view of the flexible microwave ablation catheter in Example 1 of the present invention, wherein a choke element is provided;

[0029] Figure 2a is a cross-sectional view of a flexible microwave ablation catheter in Example 2 of the present invention;

[0030] Figure 2b is a schematic diagram of the three-dimensional structure of the choke element in Embodiment 2 of the present invention;

[0031] Figure 3is a cross-sectional view of the flexible microwave ablation catheter in Example 3 of the present invention;

[0032] Figure 4 is a cross-sectional view of a flexible microwave ablation catheter in Example 4 of the present invention;

[0033] Figure 5 is a cross-sectional view of a flexible microwave ablation catheter in Example 5 of the present invention;

[0034] Figure 6 is a cross-sectional view of a flexible microwave ablation catheter in Example 6 of the present invention;

[0035] Figure 7a is a schematic diagram of a flexible microwave ablation catheter in an embodiment of the present invention when it is not bent;

[0036] Figure 7b is a schematic diagram of a flexible microwave ablation catheter bent in an embodiment of the present invention;

[0037] Figure 8a is a schematic structural diagram of a traction mechanism of a flexible microwave ablation catheter in an embodiment of the present invention, wherein the microwave antenna radiation unit is shown in an unbent state;

[0038] Figure 8b is a schematic structural diagram of a traction mechanism of a flexible microwave ablation catheter in an embodiment of the present invention, wherein a bending state of a microwave antenna radiation unit is shown;

[0039] Figure 8c is a schematic diagram of the three-dimensional structure of a traction mechanism of a flexible microwave ablation catheter in an embodiment of the present invention, wherein the bending state of the microwave antenna radiation unit is shown;

[0040] Figure 8d is a schematic structural diagram of a traction mechanism of a flexible microwave ablation catheter in another embodiment of the present invention, wherein a bending state of a microwave antenna radiation unit is shown;

[0041] Fig. 9 is a cross-sectional view of a microwave ablation system according to an embodiment of the present invention;

[0042] Fig.10a is a schematic diagram of a microwave ablation system in an electromagnetic field according to an embodiment of the present invention;

[0043] Fig.10b is a structural schematic diagram of a pushing mechanism of a flexible microwave ablation catheter in an embodiment of the present invention;

[0044] Fig.11 is a schematic structural diagram of a microwave ablation system in another embodiment of the present invention, wherein a flexible microwave ablation catheter is not installed;

[0045] Fig.12 It is a schematic structural diagram of a microwave ablation system in another embodiment of the present invention, in which a flexible microwave ablation catheter is installed.

[0046] Reference numerals:

[0047] 1. Handle housing; 2. Push reinforcement tube; 3. End cover; 4. Light shield; 5. Wiring terminal; 6. RF connector; 7. Inlet pipe; 8. Return pipe; 9. Cooling liquid chamber; 10. Fixed sheath; 11. Head end of microwave ablation catheter;

[0048] 12. main tube; 13. inner tube; 14. coaxial cable; 131. coolant inlet channel; 132. coolant return channel;

[0049] 15. Isolation element; 16. Coaxial cable insulation layer; 17. Inner conductor; 18. Outer conductor; 20. Microwave antenna radiation unit; 201. Groove; 202. Accommodation groove; 203. Plug;

[0050] 21. Temperature measuring element; 22. Flexible overlapping element; 24. Microwave antenna radiation part; 25. Microwave antenna connection part; 241. First cavity;

[0051] 26. electromagnetic sensor; 27. choke element; 28. light source; 29. ​​wire; 30. puncture part; 301. second cavity; 271. spiral blade;

[0052] 31. Adjustment device; 311. Slider; 312. Button; 313. Rotating member; 314. Connecting member; 32. Amplifier; 33. Controller; 34. Microwave signal generator; 35. Electromagnetic field generator; 36. Locking mechanism;

[0053] 37. Adjustment mechanism; 38. Luer connector; 39. Push handle; 40. Thrust mechanism; 41. Push locking mechanism; 42. Adjustment locking mechanism; 43. Outer sheath; 45. Pulling mechanism; 451. Pulling wire; 452. Pulling ring; 47. Pushing mechanism; 48. Scale. DETAILED DESCRIPTION

[0054] The present invention will be further described below in conjunction with the accompanying drawings.

[0055] According to the first aspect of the present invention, the present invention provides a microwave ablation catheter, which can be combined with a bronchoscope, and can also be combined with other endoscopes (such as gastrointestinal endoscopes, laparoscopes, electroresectionoscopes, hysteroscopes, arthroscopy, urological endoscopes, ultrasonic endoscopes, etc.), so that it can be used to treat nodules in different organs such as the liver, brain, heart, lungs, bile duct, pancreas, intestines and kidneys; or it can be used to treat varicose veins, and has the advantages of fast recovery after surgery, less impact on production and life, and fewer complications.

[0056] Example 1

[0057] like Figure 1a and Figure 1b As shown, the present invention provides a microwave ablation catheter including a main tube 12, an inner tube 13 extending in the main tube 12, and a coaxial cable 14 extending in the inner tube 13. A microwave antenna radiation unit 20 is provided at the distal end of the main tube 12, and the microwave antenna radiation unit 20 is connected to the coaxial cable 14.

[0058] The main tube 12 is the outermost component of the microwave ablation catheter, which can play a protective and supporting role. The main tube 12 can be, for example, a multi-layer composite tube structure, including an inner tube, an intermediate tube and an outer tube arranged in sequence from the inside to the outside. Among them, the inner tube is made of plastic material, preferably a flexible material such as nylon elastomer (Pebax), polyimide (PI) or thermoplastic polyurethane (TPU), so as to have a certain flexible bending performance. The intermediate tube is made of metal material, preferably stainless steel braided wire or stainless steel braided spring such as 304 or 316, or it can also be nickel-titanium braided wire or nickel-titanium spring, so as to have a certain strength and rigidity and play a supporting role. The outer tube is made of plastic material, preferably high temperature resistant materials such as polytetrafluoroethylene (PTFE), polyimide (PI) or polyfluoroethylene propylene (FEP), which plays a protective role. The inner tube, the intermediate tube and the outer tube can be connected by welding or bonding. It is understandable that the main body pipe 12 may also be a two-layer composite pipe structure including only an inner layer pipe and an outer layer pipe, or the main body pipe 12 may also be a multi-layer composite pipe structure including an inner layer pipe, a plurality of intermediate pipes and an outer layer pipe.

[0059] The inner tube 13 is between the main tube 12 and the coaxial cable 14, and is used to construct a coolant inlet channel 131 and a coolant return channel 132. The inner tube 13 is preferably a flexible thin-walled tube, and its wall thickness can be 0.01mm-0.2mm. Figure 1b As shown, the coaxial cable 14 is located in the inner tube 13, so the outer wall of the coaxial cable 14 and the outer wall of the inner tube 13 jointly define a cooling liquid inlet channel 131, that is, the cooling liquid (for example, cooling water, or liquid metal, etc.) can flow along the outer wall of the coaxial cable 14, thereby cooling the coaxial cable 14. The inner tube 13 is located outside the main tube 12, so the outer wall of the inner tube 13 and the inner wall of the main tube 12 jointly define a cooling liquid return channel 132, and the cooling liquid returns along the cooling liquid return channel 132 after being folded back at the farthest end of the coaxial cable 14. By constructing the cooling liquid inlet channel 131 and the cooling liquid return channel 132, circulating cooling water can be introduced into the interior of the microwave ablation catheter, thereby preventing tissue adhesion and making the ablation area where the microwave antenna radiation unit 20 is located closer to an ideal sphere.

[0060] The flexible coaxial cable 14 can transmit microwave energy to the microwave antenna radiation unit 20, and the microwave antenna radiation unit 20 directly contacts the lesion tissue for ablation. The flexible coaxial cable 14 includes an outer conductor 18, a coaxial cable insulation layer 16, and an inner conductor 17, which are arranged from the outside to the inside. The outer conductor 18 is composed of a braided conductive layer and a flexible tube (or metal layer). The inner conductor 17 can be conductively connected to the microwave antenna radiation unit 20. Figure 1b As shown, the proximal end of the microwave antenna radiation unit 20 is provided with a groove 201, and the inner conductor 17 is inserted into the groove 201. Figure 1b As shown, the proximal end of the microwave antenna radiation unit 20 abuts against the end of the coaxial cable insulation layer 16 of the coaxial cable 14, indicating that the inner conductor 17 is inserted into place. After the inner conductor 17 is inserted into the groove 201, the inner conductor 17 and the microwave antenna radiation unit 20 can be effectively connected by crimping or welding.

[0061] In this embodiment 1, the microwave antenna radiation unit 20 integrates the microwave antenna radiation part and the microwave antenna connection part into a whole, and the microwave antenna radiation unit 20 is located at the distal end of the microwave ablation catheter, that is, the microwave antenna radiation unit 20 can also be used as the puncture part during puncture. Figure 1a and Figure 1b An example is shown in which the distal end of the microwave antenna radiation unit 20 is a circular structure. It can be understood that the distal end of the microwave antenna radiation unit 20 can also be a solid prism structure, a solid wedge structure, a hollow prism structure or a conical structure.

[0062] It is understandable that the microwave antenna radiation unit 20 needs to have a certain strength for puncture, so it can be made of metal or ceramics. In addition, it is necessary to avoid adhesion with tissue during puncture, so an insulating anti-adhesion coating can be provided on the surface of the microwave antenna radiation unit 20.

[0063] like Figure 1a As shown, an electromagnetic sensor 26 is provided in the microwave antenna radiation unit 20 and / or in the main body tube 12 . The electromagnetic sensor 26 may be, for example, at least one electromagnetic sensor coil, which may be provided on the distal side of the microwave antenna radiation unit 20 .

[0064] Optionally or additionally, the electromagnetic sensor 26 is disposed inside the microwave antenna radiation unit 20, for example, in the distal end of the microwave antenna radiation unit 20 (eg, Figure 1a as shown).

[0065] Optionally or additionally, the electromagnetic sensor 26 may also be arranged on the proximal side of the microwave antenna radiation unit 20 , for example, the electromagnetic sensor 26 is arranged between the proximal side of the microwave antenna radiation unit 20 and the isolation element 15 located at the distal end of the main body tube 12 .

[0066] Alternatively or additionally, the electromagnetic sensor 26 may also be disposed on the coaxial cable 14 in the main body tube 12 and located between the proximal end of the isolation element 15 and the proximal end of the microwave antenna radiating unit 20 .

[0067] Alternatively or additionally, the electromagnetic sensor 26 may also be disposed in the main body tube 12 at a position between the distal end of the inner tube 13 and the proximal end of the isolation element 15 .

[0068] Electromagnetic sensor 26 can be connected to wire 29, please combine Figure 3 and Fig.10a The wire 29 is located between the inner tube 13 and the coaxial cable 14 and extends from the distal end to the proximal end of the coaxial cable 14. The wire 29 can extend from the proximal end of the microwave ablation catheter to the external terminal 5 thereof, and the terminal 5 is connected to the signal processing unit.

[0069] The wire 29 can be a twisted pair wire, and communicates with the amplifier 32 and the controller 33 and other signal processing units through the terminal 5. When the microwave ablation catheter with the electromagnetic sensor 26 enters the controllable variable magnetic field generated by the electromagnetic field generator 35, the electromagnetic sensor 26 will generate a potential difference (voltage). After the potential difference is collected and amplified by the amplifier 32, the controller 33 uses the induced voltage to calculate the position and posture of the electromagnetic sensor 26 in the controllable variable magnetic field, and the distal end of the microwave ablation catheter can be known (see Fig. 9 )’s position and direction in the patient’s body, thereby providing navigation guidance for the microwave ablation catheter when it enters the internal organs of the human body through an endoscope or natural cavity, and the relative position of the microwave ablation catheter and the lesion can be known, thereby improving the accuracy of the operation.

[0070] The outer diameter of the electromagnetic sensor coil can be 0.03mm-20mm, its length can be 13mm, and its measurement accuracy can reach 0.05mm-5mm. The electromagnetic sensor coil can also have a 2.5m long lead wire to facilitate connecting it to the wire 29.

[0071] The distal end of the microwave antenna radiation unit 20 can be used as the puncture part during puncture, so its distal end can be a solid prism structure, a solid wedge structure, a hollow prism structure or a conical structure. The microwave antenna radiation unit 20 needs to have a certain strength for puncture, so it can be made of materials such as metal or ceramic. In addition, the microwave antenna radiation unit 20 needs to avoid adhesion with the tissue during puncture, so an insulating anti-adhesion coating can be provided on the surface of the microwave antenna radiation unit 20.

[0072] The microwave ablation catheter also includes a light source, which can be arranged in various ways in the following embodiments to improve the accuracy of the operation. Figure 1aAs shown in FIG. 1 , the microwave ablation catheter is not provided with a choke element 27. Figure 1b As shown, the microwave ablation catheter further includes a choke element 27 and an isolation element 15 which are sequentially arranged at the distal end of the main body tube 12 .

[0073] The choke element 27 is located in the coolant inlet channel 131 defined by the inner tube 13 and the coaxial cable 14 and / or the coolant return channel 132 defined by the main tube 12 and the inner tube 13. Figure 1b As shown, in this embodiment 1, the choke element 27 is constructed as a metal sleeve connected to the proximal end of the main tube 12. One part of the metal sleeve is inserted into the main tube 12 and connected to the conduit exposed outside the inner tube 13. The other part of the metal sleeve is flush with the outer surface of the main tube 12 and connected to the isolation element 15. The choke element 27 can be fixed to the main tube 12 and the coaxial cable 14 by bonding or the like.

[0074] The function of the choke element 27 is that, on the one hand, the choke element 27 can prevent the microwave signal from radiating to the handle mechanism at the proximal end of the microwave ablation catheter because the choke element 27 can absorb part of the microwave signal; on the other hand, since the choke element 27 is located in the coolant inlet channel and / or the coolant return channel, the choke element 27 can increase the heat exchange area, thereby improving the cooling effect of the coolant and accelerating the cooling of the coaxial cable 14.

[0075] The isolation element 15 may be, for example, an insulating isolation sleeve, which plays a role of insulation, so that only the area where the microwave antenna radiation unit 20 is located on the microwave ablation catheter can perform heat exchange. The isolation element 15 is preferably made of a high-temperature resistant flexible material such as plastic, such as silicone, polytetrafluoroethylene (PTFE), etc. Alternatively, the isolation element 15 may also be made of a hard material such as ceramics.

[0076] The isolation element 15 can be connected to the distal end of the choke element 27 by overlapping or bonding. For example, a flexible overlapping element can be provided on the inner or outer side of the isolation element 15 and the choke element 27 to overlap and connect the two. In the embodiment where the choke element 27 is not provided, the isolation element 15 is directly overlapped or bonded to the main tube 12. Similarly, the isolation element 15 and the main tube 12 can also be connected by a flexible overlapping element. Through the flexible overlapping element, the main tube 12, the inner tube 13 and the coaxial cable 14 can form a compliant, bendable and resilient microwave ablation catheter.

[0077] The inner wall of the isolation element 15 can be connected to the microwave antenna radiation unit 20 and the outer conductor 18 of the coaxial cable 14 by bonding or the like.

[0078] In this embodiment 1, by providing a choke element 27 in the cooling liquid inlet channel 131 and / or the cooling liquid return channel 132 of the microwave ablation catheter, the microwave radiation direction can be controlled, the microwave current can be prevented from radiating to the handle mechanism at the proximal end of the microwave ablation catheter, and the ablation area formed by the microwave antenna radiation unit 20 can be closer to the ideal spherical shape, thereby avoiding the "tailing" ablation area from ablating the non-target area. In addition, the choke element 27 can play a role in conducting heat exchange, thereby improving the cooling effect of the cooling liquid.

[0079] A temperature measuring element (not shown), such as a temperature sensor or a thermocouple, may also be provided on the inner side of the main tube 12 to measure the ablation temperature. Specifically, in view of the structure of the main tube 12 being a three-layer composite tube, the temperature measuring element is preferably provided in the middle tube of the main tube 12, and less preferably in the outer tube of the main tube 12. When the temperature measured by the temperature measuring element rises, an alarm is generated at the microwave output end at the proximal end of the microwave ablation catheter, and the output microwave energy is controlled to be reduced, and the cooling strength is increased to prevent the microwave ablation catheter from ablating and scalding tissue at high power.

[0080] Please combine Fig. 9 The push reinforcement tube 2 can be arranged outside the main body tube 12, and the two can be connected by welding or bonding. The proximal end of the push reinforcement tube 2 can extend into the handle mechanism, which can provide strength for the main body tube 12 to avoid bending and damage of the main body tube 12 during soft tissue puncture.

[0081] Please combine Fig.11 The microwave ablation catheter may also include an outer sheath 43, which covers the outside of the main tube 12 and the microwave antenna radiation unit 20. The outer sheath 43 is constructed to be movable relative to the main tube 12 to adjust the length of the main tube 12 and the microwave antenna radiation unit 20 covered by the outer sheath 43.

[0082] Example 2

[0083] like Figure 2a As shown, the microwave ablation catheter of this embodiment 2 is similar to that of embodiment 1, that is, it includes a main tube 12, an inner tube 13 extending in the main tube 12, and a coaxial cable 14 extending in the inner tube 13. A microwave antenna radiation unit 20 is provided at the distal end of the main tube 12, and the microwave antenna radiation unit 20 is connected to the coaxial cable 14.

[0084] The difference between the present embodiment 2 and the above-mentioned embodiment 1 is that in the present embodiment 2, the choke element 27 is configured to extend in a spiral form on the outer wall of the inner tube 13. In the present embodiment 2, the spiral choke element 27 can increase the contact area of ​​the coolant, thereby improving the efficiency of conduction heat exchange.

[0085] Specifically, if Figure 2b As shown, the choke element 27 includes a spiral blade 271 , which extends spirally along the axial direction of the inner tube 13 . For example, the spiral blade 271 may extend spirally along the axial direction of the inner tube 13 at an equal pitch (the distance between two adjacent blades).

[0086] Furthermore, the spiral blade 271 extends spirally along the axial direction of the inner tube 13 in a twisted manner. Figure 2b As shown, two adjacent blades in the spiral blade 271 extend axially to the left and axially to the right on the same side of the inner tube 13 to form a twisted shape. After the spiral blade 271 is twisted, its contact area with the cooling water can be further increased, thereby improving the heat exchange efficiency.

[0087] In addition, the spiral blades 271 may extend continuously in the axial direction of the inner tube 13, or the spiral blades 271 may be arranged at intervals in the axial direction of the inner tube 13. It can be understood that in this case, the number of the spiral blades 271 may be multiple.

[0088] The spiral blade 271 may have a uniform thickness, or the thickness of the spiral blade 271 may gradually decrease along the radial direction of the inner tube 13 .

[0089] It can be understood that the spiral blade 271 should be made of metal material.

[0090] The difference between the second embodiment and the first embodiment is that in the second embodiment, the microwave antenna radiation unit 20 includes a split microwave antenna radiation portion 24 and a microwave antenna connection portion 25. Figure 2a As shown, the proximal side of the microwave antenna radiating portion 24 is connected to the isolation element 15 . As described above, the two can be overlapped and connected by a flexible overlap element 22 .

[0091] A first cavity 241 is provided at the proximal side of the microwave antenna radiating portion 24, one end of the microwave antenna connecting portion 25 extends into the first cavity 241, and a groove 201 is provided at the portion of the microwave antenna connecting portion 25 located in the first cavity 241, and the inner conductor 17 is inserted into the groove 201, thereby being electrically connected to the microwave antenna connecting portion 25. Figure 2a As shown, the end of the microwave antenna connection part 25 located in the first cavity 241 abuts against the end of the coaxial cable insulation layer 16 of the coaxial cable 14, indicating that the inner conductor 17 is inserted in place. After the inner conductor 17 is inserted into the groove 201, the inner conductor 17 can be effectively connected to the microwave antenna radiation unit 20 by crimping or welding.

[0092] The distal end of the microwave antenna radiating portion 24 is provided with a receiving groove 202, the other end of the microwave antenna connecting portion 25 is provided in the receiving groove 202, and the end of the microwave antenna connecting portion 25 can be fixed in the receiving groove 202 by a plug 203. The microwave antenna radiating portion 24 and the microwave antenna connecting portion 25 can be connected by a microwave signal line by welding.

[0093] The microwave antenna radiation part 24 and the plug part 203 can also be used as the puncture part during puncture. Figure 2a An example is shown in which the distal end of the microwave antenna radiation portion 24 and the plug portion 203 together form a circular puncture portion. It can be understood that the puncture portion formed therein can also be a solid prism structure, a solid wedge structure, a hollow prism structure or a conical structure.

[0094] It is understandable that the microwave antenna radiating portion 24 and the plug portion 203 need to have a certain strength to facilitate puncture, so they can be made of materials such as metal or ceramic. In addition, the microwave antenna radiating portion 24 and the plug portion 203 need to avoid adhesion to tissue during puncture, so an insulating anti-adhesion coating can be provided on the surface of the microwave antenna radiating portion 24 and the surface of the plug portion 203.

[0095] like Figure 2a As shown, the first cavity 241 can be connected to the cooling liquid inlet channel 131 and the cooling liquid return channel 132. The distal end of the inner tube 13 extends to penetrate the isolation element 15 and extend into the first cavity 241, and the distal end of the inner tube 13 is an open end, so the cooling liquid inlet channel 131 is in fluid communication with the first cavity 241. The first cavity 241 can have the same inner diameter as the main tube 12 and the isolation element 15, so the first cavity 241, the isolation element 15 and the cooling liquid return channel 132 are in fluid communication. The cooling liquid flows into the first cavity 241 from the cooling liquid inlet channel 131. Since the distal end of the first cavity 241 is closed by the microwave antenna connecting portion 25, the cooling liquid flows back to the cooling liquid return channel 132 in the first cavity 241 and flows in a direction opposite to the flow direction in the cooling liquid inlet channel 131.

[0096] like Figure 2a As shown, the isolation element 15 is located between the main tube 12 and the microwave antenna radiating portion 24, so the main tube 12, the isolation element 15 and the microwave antenna radiating portion 24 can be overlapped and connected as a whole through the flexible overlap element 22 on the inner or outer side thereof, or the main tube 12 and the isolation element 15 as well as the isolation element 15 and the microwave antenna radiating portion 24 can be overlapped and connected to each other through multiple flexible overlap elements 22.

[0097] like Figure 2aAs shown, a temperature measuring element 21, such as a temperature sensor or a thermocouple, can be further provided on the inner side of the main tube 12 to measure the ablation temperature. Specifically, in view of the structure of the main tube 12 being a three-layer composite tube, the temperature measuring element 21 is preferably provided in the middle tube of the main tube 12, and less preferably provided in the outer tube of the main tube 12. When the temperature measured by the temperature measuring element rises, the microwave output end at the proximal end of the microwave ablation catheter will alarm and control the output microwave energy to decrease, and increase the cooling intensity, so as to avoid the microwave ablation catheter from ablating and scalding tissue at high power.

[0098] The similarities between Example 2 and Example 1 will not be repeated here.

[0099] Example 3

[0100] like Figure 3 As shown, the microwave ablation catheter of this embodiment 3 is similar to the embodiments 2 and 1, that is, it includes a main body tube 12, an inner tube 13 extending in the main body tube 12, and a coaxial cable 14 extending in the inner tube 13. A microwave antenna radiating unit 20 is provided at the distal end of the main body tube 12, and the microwave antenna radiating unit 20 is connected to the coaxial cable 14. Figure 3 As shown, the microwave ablation catheter of the present embodiment 3 is different from that of the embodiment 2 in that the microwave antenna radiation unit 20 includes a microwave antenna radiation portion 24 and a microwave antenna connection portion 25, which can be connected by a microwave signal line through welding.

[0101] An electromagnetic sensor 26 is disposed inside the microwave antenna radiation unit 20. Specifically, a first cavity 241 is disposed inside the microwave antenna radiation unit 24, one end of the microwave antenna connection unit 25 extends into the first cavity 241, and a groove 201 is disposed at the portion of the microwave antenna connection unit 25 located in the first cavity 241, and the inner conductor 17 is inserted into the groove 201, thereby being electrically connected to the microwave antenna connection unit 25. Figure 3 As shown, the end of the microwave antenna connection part 25 located in the first cavity 241 abuts against the end of the coaxial cable insulation layer 16 of the coaxial cable 14, indicating that the inner conductor 17 is inserted in place. After the inner conductor 17 is inserted into the groove 201, the inner conductor 17 can be effectively connected to the microwave antenna radiation unit 20 by crimping or welding.

[0102] A receiving groove 202 is provided at the distal end of the microwave antenna radiating portion 24 , and the other end of the microwave antenna connecting portion 25 is provided in the receiving groove 202 , and the end of the microwave antenna connecting portion 25 can be fixed in the receiving groove 202 by a plug portion 203 .

[0103] The electromagnetic sensor 26 is disposed in the first cavity 241. The electromagnetic sensor 26 may be, for example, at least one electromagnetic sensor coil, which is wound around the portion of the microwave antenna connection portion 25 located in the first cavity 241 (ie, the portion located outside the inner conductor 17).

[0104] like Figure 3 Please combine Fig.10a The electromagnetic sensor 26 is connected to a wire 29, which is located between the inner tube 13 and the coaxial cable 14 and extends from the distal end to the proximal end of the coaxial cable 14. The wire 29 can extend from the proximal end of the microwave ablation catheter to the external terminal 5 thereof, and the terminal 5 is connected to the signal processing unit.

[0105] The wire 29 can be a twisted pair wire, and communicates with the signal processing units such as the amplifier 32 and the controller 33 through the terminal 5.

[0106] When the microwave ablation catheter with the electromagnetic sensor 26 enters the controllable variable magnetic field generated by the electromagnetic field generator 35, the electromagnetic sensor 26 generates a potential difference (voltage). After the potential difference is collected and amplified by the amplifier 32, the controller 33 uses the induced voltage to calculate the position and posture of the electromagnetic sensor 26 in the controllable variable magnetic field, and the distal end of the microwave ablation catheter can be known (see Fig. 9 )’s position and direction in the patient’s body, thereby providing navigation guidance for the microwave ablation catheter when it enters the internal organs of the human body through an endoscope or natural cavity, and the relative position of the microwave ablation catheter and the lesion can be known, thereby improving the accuracy of the operation.

[0107] The outer diameter of the electromagnetic sensor coil can be 0.03mm-20mm, its length can be 13mm, and its measurement accuracy can reach 0.05mm-5mm. The electromagnetic sensor coil can also have a 2.5m long lead wire to facilitate connecting it to the wire 29.

[0108] The microwave antenna radiation part 24 and the plug part 203 can also be used as the puncture part during puncture. Figure 3 An example of a puncture portion in which the distal end of the microwave antenna radiating portion 24 and the plug portion 203 together form a circular structure is shown. It can be understood that the distal end of the microwave antenna radiating portion 24 and the plug portion 203 can also be a solid prism structure, a solid wedge structure, a hollow prism structure or a conical structure. The microwave antenna radiating portion 24 and the plug portion 203 need to have a certain strength in order to perform puncture, so they can be made of materials such as metal or ceramic. In addition, the microwave antenna radiating portion 24 and the plug portion 203 need to avoid adhesion with the tissue during puncture, so an insulating anti-adhesion coating can be provided on the surface of the microwave antenna radiating portion 24 and the surface of the plug portion 203.

[0109] like Figure 3As shown, the outer portion of the inner tube 13 is arranged in the same manner as in the second embodiment, that is, a spiral choke element 27 is arranged. It can be understood that the choke element 27 may not be arranged in the third embodiment.

[0110] The microwave ablation catheter also includes a light source 28, such as Figure 3 As shown, the light source 28 can be disposed on the inner side of the main tube 12, the inner side of the isolation element 15, or in the first cavity 241. The light source 28 can be disposed around the circumference of the main tube 12. When the microwave ablation catheter enters the superficial vein of the lower limb through percutaneous puncture, the light source 28 can provide navigation introduction for superficial treatment, and the relative position of the microwave ablation catheter and the lesion can be observed, thereby improving the accuracy of the operation.

[0111] The number of the light sources 28 may be one or more. The plurality of light sources 28 may be arranged at intervals along the axial direction and / or circumferential direction of the main body tube 12. Preferably, the light source 28 is arranged as close to the distal end of the main body tube 12 as possible to provide a better indication effect. However, it should be noted that the light source 28 needs to maintain a certain safety distance from the proximal end of the microwave antenna radiation unit 20 or the proximal end of the microwave antenna connection part 25.

[0112] The light source 28 may be, for example, an LED light strip, or a self-luminous body.

[0113] Therefore, the electromagnetic sensor 26 and light source 28 of the microwave ablation catheter of the present invention can realize the visual positioning and electromagnetic positioning navigation functions of the ablation microwave ablation catheter, so that it can be flexibly adapted to different types of endoscopes to treat lesions in different scenarios.

[0114] The similarities between this embodiment 3 and embodiment 2 and embodiment 1 will not be repeated again.

[0115] Example 4

[0116] like Figure 4 As shown, the microwave ablation catheter of this embodiment 4 is similar to that of embodiment 3, that is, it includes a main body tube 12, an inner tube 13 extending in the main body tube 12, and a coaxial cable 14 extending in the inner tube 13. A microwave antenna radiation unit 20 is provided at the distal end of the main body tube 12, and the microwave antenna radiation unit 20 is connected to the coaxial cable 14. The microwave antenna radiation unit 20 includes a microwave antenna radiation portion 24 and a microwave antenna connection portion 25, and the two can be connected by a microwave signal line through welding.

[0117] The difference between the present embodiment 4 and the above-mentioned embodiment 3 is that the microwave antenna connection part 25 extends into the first cavity 241 and is connected to the coaxial cable 14, and the other end of the microwave antenna connection part 25 serves as a puncture part. Figure 4 As shown, the microwave antenna connecting portion 25 is in the shape of an arrow as a whole, and its tip is more convenient for puncture.

[0118] Figure 4 An example of a puncture portion in which the microwave antenna connection portion 25 is a triangular pyramid structure is shown. It can be understood that the microwave antenna connection portion 25 can also be a circular structure, a solid prism structure, a solid wedge structure, a hollow prism structure or a conical structure. The microwave antenna connection portion 25 needs to have a certain strength for puncture, so it can be made of materials such as metal or ceramic. In addition, the microwave antenna connection portion 25 needs to avoid adhesion with the tissue during puncture, so an insulating anti-adhesion coating can be provided on the surface of the microwave antenna connection portion 25.

[0119] The electromagnetic sensor 26 may be arranged in the same manner as in Example 3, for example, may be at least one electromagnetic sensor coil, and the at least one electromagnetic sensor coil is wound around the portion of the microwave antenna connecting portion 25 located in the first cavity 241 .

[0120] like Figure 4 As shown, the outer portion of the inner tube 13 is arranged in the same manner as in the second embodiment, that is, a spiral choke element 27 is arranged. It can be understood that the choke element 27 may not be arranged in the fourth embodiment.

[0121] The similarities between Example 4 and Example 3 will not be repeated here.

[0122] Example 5

[0123] like Figure 5 As shown, the microwave ablation catheter of this embodiment 5 is similar to that of embodiment 3, that is, it includes a main body tube 12, an inner tube 13 extending in the main body tube 12, and a coaxial cable 14 extending in the inner tube 13. A microwave antenna radiation unit 20 is provided at the distal end of the main body tube 12, and the microwave antenna radiation unit 20 is connected to the coaxial cable 14. The microwave antenna radiation unit 20 includes a microwave antenna radiation portion 24 and a microwave antenna connection portion 25, and the two can be connected by a microwave signal line through welding.

[0124] The difference between the present embodiment 5 and the above-mentioned embodiment 3 is that a puncture portion 30 having a second cavity 301 is provided at the distal end side of the microwave antenna radiating portion 24, and the microwave antenna radiating portion 24 is fixedly connected to the puncture portion 30. The electromagnetic sensor 26 is provided in the second cavity 301. The electromagnetic sensor 26 can be fixed in the second cavity 301 by bonding, welding, etc., or necessary connecting components or supporting components can be provided to fix the electromagnetic sensor 26 in the second cavity 301.

[0125] like Figure 5As shown, one end of the microwave antenna connecting part 25 extends into the first cavity 241 and is connected to the coaxial cable 14 , and the other end of the microwave antenna connecting part 25 is located in the second cavity 301 of the puncture part 30 and is separated from the electromagnetic sensor 26 .

[0126] The puncture portion 30 may be a tubular structure with a closed distal end, and the electromagnetic sensor 26 is located inside the puncture portion 30, so that during the puncture positioning process of the microwave ablation catheter, the electromagnetic sensor 26 can be effectively protected. The puncture portion 30 may adopt the same structure as in the above embodiments, for example, it may be a circular structure, a solid prism structure, a solid wedge structure, a hollow prism structure or a conical structure.

[0127] The puncture portion 30 needs to have a certain strength for puncturing, so it can be made of materials such as metal or ceramic. In addition, the puncture portion 30 needs to avoid adhesion with the tissue during puncture, so an insulating anti-adhesion coating can be provided on the surface of the puncture portion 30.

[0128] Since the electromagnetic sensor 26 is disposed in the second cavity 301, the wire 29 connected thereto needs to pass through the microwave antenna radiating portion 24 and the microwave antenna connecting portion 25 to be connected to the electromagnetic sensor 26. In order to facilitate the insertion of the wire 29, a threading hole for the wire to pass through can be provided on the microwave antenna radiating portion 24 and the microwave antenna connecting portion 25.

[0129] like Figure 5 As shown, the outer portion of the inner tube 13 is arranged in the same manner as in Embodiment 2, that is, a spiral choke element 27 is arranged. It can be understood that the choke element 27 may not be arranged in this Embodiment 5.

[0130] The similarities between Example 5 and Example 3 will not be repeated here.

[0131] Example 6

[0132] like Figure 6 As shown, the microwave ablation catheter of this embodiment 6 is similar to that of embodiment 5, that is, it includes a main body tube 12, an inner tube 13 extending in the main body tube 12, and a coaxial cable 14 extending in the inner tube 13. A microwave antenna radiation unit 20 is provided at the distal end of the main body tube 12, and the microwave antenna radiation unit 20 is connected to the coaxial cable 14. The microwave antenna radiation unit 20 includes a microwave antenna radiation portion 24 and a microwave antenna connection portion 25, and the two can be connected by a microwave signal line through welding.

[0133] The difference between the present embodiment 6 and the above-mentioned embodiment 5 is that the puncture portion 30 is in the form of a triangular pyramid structure, that is, the puncture portion 30 is in the shape of an arrow as a whole, and its tip is more convenient for puncture.

[0134] like Figure 6As shown, the outer portion of the inner tube 13 is arranged in the same manner as in the second embodiment, that is, a spiral choke element 27 is arranged. It can be understood that the choke element 27 may not be arranged in the sixth embodiment.

[0135] The similarities between Example 6 and Example 5 will not be repeated here.

[0136] Example 7

[0137] like Figure 7a and Figure 7b As shown, based on the above-mentioned embodiments 1 to 6, the microwave ablation catheter of this embodiment 7 can achieve distal end bending adjustment.

[0138] Specifically, the main body tube 12 is provided with a traction mechanism 45, which is configured to bend the isolation element 15 relative to the axial direction of the main body tube 12. The traction mechanism 45 can be, for example, a bending traction wire, which can be provided in the inner tube, the middle tube or the outer tube of the main body tube 12.

[0139] The proximal end of the traction mechanism 45 extends into the handle mechanism and is connected to the adjustment device 31 in the handle mechanism. The adjustment device 31 can, for example, drive the traction mechanism 45 by pushing, pulling and / or rotating, so as to bend the distal end of the microwave ablation catheter.

[0140] As described above, the main body tube 12, the isolation element 15 and the microwave antenna radiating portion 24 can be connected in an integral manner by means of the flexible overlap element 22, or the main body tube 12 and the isolation element 15, and the isolation element 15 and the microwave antenna radiating portion 24 can be connected to each other by means of a plurality of flexible overlap elements 22. Therefore, by pulling or pushing the traction mechanism 45, the main body tube 12 can be driven to bend upward or downward (such as Figure 7b As shown), the bending position can occur at the distal end of the main tube 12, the isolation element 15 or the microwave antenna radiating portion 24, such as the position where the flexible lap element 22 is located.

[0141] In addition, after the distal end of the microwave ablation catheter is bent, Figure 7b In the state shown, it can also be rebounded to Figure 7a That is to say, the microwave ablation catheter of the present invention can realize the functions of flexible bending and rebound, thereby meeting the requirements of large-volume and high-efficiency microwave ablation of tissues.

[0142] The bending angle of the distal end of the main tube 12, the distal end of the isolation element 15 or the distal end of the microwave antenna radiating portion 24 is 0°-360°, for example, Figure 7a The unbent state shown is bent upward 90 degrees or bent downward 90 degrees, as shown Figure 7bThe distal end of the main body tube 12, the distal end of the isolation element 15 or the distal end of the microwave antenna radiating portion 24 may also have a larger bending angle, such as 180° or 270°.

[0143] In particular, when the distal bending adjustment scheme in Example 7 is combined with the scheme of the electromagnetic sensor 26 in Examples 3 to 6, the bending angle of the distal end of the microwave ablation catheter can be specifically adjusted according to the position and direction of the distal end of the microwave ablation catheter in the patient's body to achieve microwave ablation in special positions and special areas.

[0144] like Figure 8a and Figure 8b As shown, the traction mechanism 45 includes a traction line 451 and a traction ring 452 connected to the distal end of the traction line 451. There can be multiple traction rings 452, and each traction ring 452 can be respectively sleeved on one or more of the distal ends of the main body tube 12, the distal ends of the isolation element 15, and the distal ends of the microwave antenna radiation part 24 (or the microwave antenna radiation unit 20), and fixedly connected thereto. Alternatively, the traction ring 452 can also be sleeved on the distal end of the coaxial cable 14 and fixedly connected thereto.

[0145] The traction wire 451 can extend in parallel with the main body tube 12 in the main body tube 12, the proximal end of the traction wire 451 is connected to the handle mechanism, and the distal end of the traction wire 451 can be respectively connected to the main body tube 12, the isolation element 15 and the microwave antenna radiating portion 24 (which can also be the microwave antenna radiating unit 20) through the traction ring 452. Therefore, at the handle mechanism, by controlling the proximal end of the traction wire 451, one or more of the main body tube 12, the isolation element 15 and the microwave antenna radiating portion 24 (which can also be the microwave antenna radiating unit 20) can be controlled to bend (such as Figure 8b ), or restore the unbent straight line state (as shown in Figure 8b as shown).

[0146] The traction ring 452 may be a metal ring, and when it is fixed to one or more of the main tube 12, the isolation element 15 and the microwave antenna radiating portion 24 (which may also be the microwave antenna radiating unit 20), it will not affect the conductive properties thereof.

[0147] The traction mechanism 45 is also connected to the adjustment device 31 described below. The adjustment device 31 is configured to bend one or more of the main tube 12, the isolation element 15 and the microwave antenna radiating portion 24 (which may also be the microwave antenna radiating unit 20) upward or downward by moving or rotating.

[0148] In one embodiment, the adjusting device 31 is configured to bend one or more of the main tube 12, the isolation element 15 and the microwave antenna radiating portion 24 (which may also be the microwave antenna radiating unit 20) upward or downward by moving. Figure 8c As shown, the adjustment device 31 includes a slider 311 and a button 312 fixedly connected to the slider 311. The slider 311 is connected to the proximal end of the traction line 451, and the slider 311 is movably arranged inside the handle mechanism, and the button 312 is located on the outer wall of the handle mechanism for easy operation. When it is necessary to bend one or more of the main body tube 12, the isolation element 15 and the microwave antenna radiating part 24 (which can also be the microwave antenna radiating unit 20), the slider 311 can be moved toward the proximal end or toward the distal end by pushing or pulling the button 312, so that one or more of the main body tube 12, the isolation element 15 and the microwave antenna radiating part 24 (which can also be the microwave antenna radiating unit 20) are bent upward or downward.

[0149] Furthermore, if Figure 8c As shown, a locking mechanism 36 is also provided on the adjusting device 31. The locking mechanism 36 can be, for example, an external thread constructed on the outer wall of the slider 311, which cooperates with the internal thread on the inner side of the handle mechanism, so that the rotational motion of the slider 311 can be converted into the linear motion of the traction line 451, and when the slider 311 is adjusted to a certain position, the slider 311 can be locked in the current position through the meshing action between the internal thread and the external thread.

[0150] In another embodiment, the adjusting device 31 is configured to bend one or more of the main tube 12, the isolation element 15 and the microwave antenna radiating portion 24 (which may also be the microwave antenna radiating unit 20) upward or downward by rotating. Figure 8d As shown, the adjusting device 31 includes a rotating member 313 and a connecting member 314 located in the rotating member 313. The connecting member 314 is fixedly connected to the rotating member 313, the rotating member 313 is rotatably connected to the handle mechanism, and the slider 311 is connected to the proximal end of the traction line 451. By rotating the rotating member 313, the relative position between the rotating member 313 and the handle mechanism is changed, thereby driving the relative position between the slider 311 and the handle mechanism, thereby pulling the traction line 451, so that one or more of the main body tube 12, the isolation element 15 and the microwave antenna radiation portion 24 (which can also be the microwave antenna radiation unit 20) are bent upward or downward.

[0151] When it is necessary to bend one or more of the main tube 12, the isolation element 15 and the microwave antenna radiating portion 24 (which can also be the microwave antenna radiating unit 20), the rotating member 313 can be rotated so that the rotating member 313 and the connecting member 314 pull the traction line 451, thereby bending one or more of the main tube 12, the isolation element 15 and the microwave antenna radiating portion 24 (which can also be the microwave antenna radiating unit 20) upward or downward.

[0152] Furthermore, if Figure 8d As shown, a locking mechanism 36 is also provided on the adjusting device 31. The locking mechanism 36 can be, for example, an internal thread constructed on the inner wall of the rotating member, which cooperates with the external thread on the handle mechanism, so that the rotational motion of the rotating member 313 can be converted into the linear motion of the traction line 451, and when the rotating member 313 is adjusted to a certain position, the rotating member 313 can be locked in the current position through the meshing action between the internal thread and the external thread.

[0153] Furthermore, the rotating member 313 may be constructed as a gear structure, which meshes with an operating gear on the handle mechanism, so that the rotating member 313 may be operated more conveniently.

[0154] Therefore, the distal bending adjustment scheme of the microwave ablation catheter of the present invention can flexibly adjust the distal posture and soft tissue puncture function of the microwave ablation catheter, so as to be flexibly adapted to different types of endoscopic treatments of lesions in different scenarios.

[0155] Example 8

[0156] like Fig. 9 and Fig.10a , Fig.10b As shown, based on the above-mentioned embodiments 1 to 7, the present invention further provides a microwave ablation system, including the above-mentioned microwave ablation catheter and a handle mechanism, wherein the proximal end of the microwave ablation catheter extends into the handle mechanism.

[0157] like Fig. 9 As shown, the handle mechanism includes a handle housing 1, which is constructed in a pistol-like structure, one end of which is used for the proximal end of the microwave ablation catheter to penetrate, and the lower end of which can provide a position convenient for holding.

[0158] like Fig. 9As shown, the microwave ablation system includes an inlet pipe 7 and a return pipe 8 extending into the handle housing 1, and the inlet pipe 7 and the return pipe 8 are both connected to the fluid in the cooling liquid chamber 9 of the handle housing 1, and the cooling liquid chamber 9 is respectively connected to the cooling liquid inlet channel 131 and the cooling liquid return channel 132, so the cooling liquid can flow into the cooling liquid chamber 9 through the inlet pipe 7 and into the cooling liquid inlet channel 131. The cooling liquid after heat exchange in the cooling liquid return channel 132 returns to the cooling liquid chamber 9, and flows to the outside of the handle housing 1 through the return pipe 8.

[0159] The cooling liquid chamber 9 can be constructed as two physically isolated chambers, which are respectively in fluid communication with the cooling liquid inlet channel 131 and the cooling liquid return channel 132. The inlet pipe 7 and the return pipe 8 are respectively connected to the cooling liquid chamber 9 through an inlet pipe joint and a return pipe structure.

[0160] like Fig.10a As shown, the microwave ablation system also includes an amplifier 32, a microwave signal generator 34, and an electromagnetic field generator 35 for generating an electromagnetic field. The amplifier 32 is electrically connected to the controller 33 and the electromagnetic sensor 26, respectively. The wire 29 connected to the electromagnetic sensor 26 extends into the handle housing 1, and is connected to the amplifier 32 through the terminal 5 inside the handle housing 1. Therefore, when the microwave ablation catheter with the electromagnetic sensor 26 enters the controllable variable magnetic field generated by the electromagnetic field generator 35, the electromagnetic sensor 26 will generate a potential difference (voltage). After the potential difference is collected and amplified by the amplifier 32 through the wire 29, the controller 33 can calculate the position and posture of the electromagnetic sensor 26 in the controllable variable magnetic field using the induced voltage, and the position and direction of the distal end of the microwave ablation catheter in the patient's body can be known, thereby providing navigation introduction for the microwave ablation catheter to enter the internal organs of the human body through an endoscope or a natural cavity, and the relative position of the microwave ablation catheter and the lesion can be known, thereby improving the accuracy of the operation.

[0161] The microwave signal generator 34 is connected to the proximal end of the coaxial cable 14 so as to transmit microwave energy to the coaxial cable 14 .

[0162] like Fig.10a As shown, the distal end of the handle housing 1 is provided with an end cap 3, and when the end cap 3 is removed, the installation and connection of the internal structure of the handle housing 1 can be facilitated. A fixing sheath 10 is provided on the outside of the end cap 3, and the fixing sheath 10 is used to fix the main body tube 12 or the push reinforcement tube 2. A shading plate 4 is also provided inside the handle housing 1. The shading plate 4 is located around the wiring terminal 5 to block the influence of the external light source on the wiring terminal 5.

[0163] like Fig. 9 As shown, the head end 11 (or distal end) of the microwave ablation catheter described above includes a microwave antenna radiation unit 20, an isolation element 15, a temperature measuring element, and the like.

[0164] Please refer to Figure 7a and Figure 7b ,as well as Figure 8c and Figure 8d The handle housing 1 is also provided with an adjusting device 31 and a locking mechanism 36 connected to the adjusting device 31. The adjusting device 31 is connected to a traction mechanism 45 in the main body tube 12. The adjusting device 31 drives the traction mechanism 45 by pushing, pulling and / or rotating, so that the distal end of the microwave ablation catheter is bent. The locking mechanism 36 keeps the adjusting device 31 in the adjusted position, thereby ensuring that the angle of the distal end of the microwave ablation catheter remains unchanged after bending.

[0165] In one embodiment, the adjustment device 31 includes a push button on the outside of the handle housing 1 and a pull rod in the handle housing 1. By pushing the push button downward, the pull rod can pull the traction mechanism 45 to shrink it, and the distal end of the microwave ablation catheter can be bent downward. Conversely, the distal end of the microwave ablation catheter can be bent upward. More specifically, various embodiments in the above-mentioned embodiment 7 can be used.

[0166] In one embodiment, the adjustment device 31 includes a knob on the outside of the handle housing 1 and a reel in the handle housing 1, and the distal end of the traction mechanism 45 is wound on the reel. By rotating the knob, the reel is wound or unwound, so that the traction mechanism 45 can be pulled or pushed, so that the distal end of the microwave ablation catheter is bent upward or downward. In this embodiment, the locking mechanism 36 can be a ratchet, and when the ratchet cooperates with the teeth on the reel, the traction mechanism 45 can be maintained in the current state, thereby ensuring that the angle of the distal end of the microwave ablation catheter remains unchanged after bending. When the ratchet is disengaged from the teeth on the reel, the knob can be rotated to adjust the bending angle of the distal end of the microwave ablation catheter.

[0167] In addition, if Fig.10b As shown, a pushing mechanism 47 may also be provided in the handle housing 1, which may be connected to the main body tube 12, and the pushing mechanism may assist the operator in completing soft tissue puncture. A scale 48 may be provided on the pushing mechanism 47, so that the pushing distance of the main body tube 12 can be strictly controlled. An indicator mark may be provided at the proximal end of the main body tube 12, which is aligned with the scale on the scale 48 to indicate the pushing distance.

[0168] Example 9

[0169] like Fig.11 and Fig.12 As shown, based on the above-mentioned embodiments 1 to 7, the present invention further provides a microwave ablation system, including the above-mentioned microwave ablation catheter and a handle mechanism, wherein the proximal end of the microwave ablation catheter extends into the handle mechanism.

[0170] like Fig.11As shown, the difference between this embodiment 9 and the above embodiment 9 is that the handle mechanism includes a push handle 39, and the push handle 39 is constructed as a linear structure. In addition, the handle mechanism also includes an adjustment mechanism 37 connected to the push handle 39 and a Luer connector 38 connected to the adjustment mechanism 37, the main tube 12 of the microwave ablation catheter is connected to the push handle 39, and the outer sheath tube 43 of the microwave ablation catheter is connected to the adjustment mechanism 37.

[0171] The push handle 39 is pushed forward by a slideway or a thread rotation on the adjustment mechanism 37, so that the main body tube 12 can slide out of the outer sheath tube 43 to achieve puncture of the soft tissue.

[0172] The Luer connector 38 on the adjustment mechanism 37 can be connected to an endoscope such as an ultrasonic endoscope, through which the change in the working length of the outer sheath can be observed, and the length of the main tube 12 extending from the outer sheath 43 can be adjusted by pushing the push handle 39 on the adjustment mechanism 37 by sliding or rotating the thread.

[0173] The push handle 39 is also provided with a push stop mechanism 40, a push locking mechanism 41 and an adjustment locking mechanism 42. The push stop mechanism 40 can limit the maximum adjustment distance of the push handle 39 to prevent the microwave ablation catheter from puncturing the tissue too deeply and damaging the tissue outside the lesion.

[0174] The push locking mechanism 41 is connected to the push handle 39 and the adjustment mechanism 37 respectively, and can fix the push handle 39 in the adjusted position to prevent the microwave ablation catheter from sliding. The adjustment locking mechanism 42 is connected to the adjustment mechanism 37 and the outer sheath 43 respectively to fix the outer sheath 43 in the adjusted position, thereby locking the length of the main tube 12 extending from the outer sheath 43.

[0175] It should be noted that, in the present invention, the “distal end” refers to an end close to the puncture portion 30 of the microwave ablation catheter, and the “proximal end” refers to an end far from the puncture portion 30 of the microwave ablation catheter.

[0176] Although the present invention has been described with reference to preferred embodiments, various modifications may be made thereto and parts thereof may be replaced by equivalents without departing from the scope of the present invention. In particular, the various technical features mentioned in the various embodiments may be combined in any manner as long as there are no structural conflicts. The present invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A microwave ablation catheter, characterized in that: The invention comprises a main body tube (12), an inner tube (13) extending in the main body tube (12), and a coaxial cable (14) extending in the inner tube (13); a microwave antenna radiation unit (20) is arranged at the distal end of the main body tube (12), and the microwave antenna radiation unit (20) is connected to the coaxial cable (14); an isolation element (15) is connected between the distal end side of the main body tube (12) and the proximal end side of the microwave antenna radiation unit (20); and the main body tube (12), the isolation element (15) and the microwave antenna radiation unit (20) are overlapped and connected; Wherein, the microwave antenna radiation unit (20) is provided with an electromagnetic sensor (26); The microwave antenna radiation unit (20) comprises a microwave antenna radiation portion (24) located at the distal end of the main body tube (12) and a microwave antenna connection portion (25) conductively connected to the microwave antenna radiation portion (24). A first cavity (241) is provided inside the microwave antenna radiating portion (24), and a second cavity (301) is provided on the distal end side of the microwave antenna radiating portion (24); The first end of the microwave antenna connection part (25) extends into the first cavity (241) and is connected to the coaxial cable (14), and the second end of the microwave antenna connection part (25) is located in the second cavity (301); The electromagnetic sensor (26) comprises at least one electromagnetic sensor coil arranged in the second cavity (301), and the at least one electromagnetic sensor coil is arranged at a distance from the second end of the microwave antenna connecting portion (25).

2. The microwave ablation catheter according to claim 1, characterized in that: The electromagnetic sensor (26) is arranged in the first cavity (241).

3. The microwave ablation catheter according to claim 2, characterized in that: At least one electromagnetic sensor coil is wound around the portion of the microwave antenna connection portion (25) located in the first cavity (241).

4. The microwave ablation catheter according to any one of claims 1 to 3, characterized in that: The electromagnetic sensor (26) is connected to a wire (29), and the wire (29) is located between the inner tube (13) and the coaxial cable (14), and extends from the distal end to the proximal end of the coaxial cable (14).

5. The microwave ablation catheter according to any one of claims 1 to 3, characterized in that: The distal end side of the microwave antenna radiation unit (20) is provided with a puncture portion, or the distal end side of the microwave antenna radiation unit (20) is integrated with the puncture portion.

6. The microwave ablation catheter according to any one of claims 1 to 3, characterized in that: One or more light sources (28) are also arranged between the main tube (12) and the inner tube (13).

7. The microwave ablation catheter according to claim 1, characterized in that: A traction mechanism (45) is provided in the main body tube (12), and the traction mechanism (45) is configured to be able to bend one or more of the main body tube (12), the isolation element (15), and the microwave antenna radiation unit (20).

8. The microwave ablation catheter according to any one of claims 1 to 3, characterized in that: It also includes a choke element (27), wherein the choke element (27) is located in a coolant inlet channel defined by the inner tube (13) and the coaxial cable (14) and / or a coolant return channel defined by the main tube (12) and the inner tube (13); The choke element (27) is constructed as a metal coil extending in a spiral form on the outer wall of the inner tube (13) and / or a metal sleeve connected to the proximal end of the main body tube (12).

9. The microwave ablation catheter according to any one of claims 1 to 3, characterized in that: It also includes an outer sheath tube (43), which covers the outside of the main tube (12) and the microwave antenna radiation unit (20), and the outer sheath tube (43) is constructed to be movable relative to the main tube (12) to adjust the length of the main tube (12) and the microwave antenna radiation unit (20) covered by the outer sheath tube (43).

10. A microwave ablation system, characterized in that: The microwave ablation catheter comprises the microwave ablation catheter according to any one of claims 1 to 9, further comprising a handle mechanism, wherein the proximal end of the microwave ablation catheter extends into the handle mechanism.

11. The microwave ablation system according to claim 10, characterized in that: It also includes an inlet tube (7) and a return tube (8) extending into the handle mechanism, wherein the inlet tube (7) is in fluid communication with a coolant inlet channel defined by the inner tube (13) and the coaxial cable (14), and the return tube (8) is in fluid communication with a coolant return channel defined by the main tube (12) and the inner tube (13).

12. The microwave ablation system according to claim 10 or 11, characterized in that: The handle mechanism comprises a handle housing (1), an amplifier (32), a controller (33) and a microwave signal generator (34); the amplifier (32) is electrically connected to the controller (33) and the electromagnetic sensor (26), respectively; and the microwave signal generator (34) is connected to the proximal end of the coaxial cable (14).

13. The microwave ablation system according to claim 12, characterized in that: The handle housing (1) is also provided with an adjusting device (31) and a locking mechanism (36) connected to the adjusting device (31); the adjusting device (31) is connected to a traction mechanism (45) in the main body tube (12); the adjusting device (31) drives the traction mechanism (45) by pushing, pulling and / or rotating.

14. The microwave ablation system according to claim 10 or 11, characterized in that: The handle mechanism comprises a pushing handle (39), an adjusting mechanism (37) connected to the pushing handle (39), and a Luer connector (38) connected to the adjusting mechanism (37); the proximal end of the microwave ablation catheter is connected to the adjusting mechanism (37).

Images