Female antibacterial liquid and application thereof
By combining extracts such as rose extract and other ingredients, the problem that existing nursing products are difficult to take into account multiple indicators has been solved, and the odor, color, sense of use and antibacterial effect has been improved, effectively fighting E. coli and gold Staphylococcus aureus and Candida albicans.
Patent Information
- Application Number
- CN202411344203.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-25
- Publication Date
- 2024-12-31
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing female care products are difficult to take into account multiple indicators such as odor, color, use effect and use feeling, which leads to low acceptance and lacks effective antibacterial effects on bacteria such as E. coli, Staphylococcus aureus and Candida albicans.
Rose extract, vitiligo extract, saffron extract, sesame extract, camellia extract, grape seed extract, kachi tima extract, jasmine extract, marina extract, saffron extract, glycerin and bone The combination of rubber and other ingredients is extracted by carbon dioxide supercritical extraction method, and the female antibacterial liquid formed has the effects of color tuning, anti-corrosion, fragrance, anti-inflammatory and antibacterial effects.
This antibacterial liquid not only has the appropriate odor and color, but also has a good experience in use, but also can effectively inhibit E. coli, Staphylococcus aureus and Candida albicans, improving the acceptance of care products and antibacterial effects.
Smart Images
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Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of female care products, and in particular relates to a female antibacterial liquid and application thereof. Background Art
[0002] It is common and necessary for women to carry out daily health care, mainly because in daily life, there are many factors that make women susceptible to bacterial infection, such as poor personal hygiene habits, sexually transmitted infections, friction from tight clothing, etc., and local flora imbalance caused by changes in hormone levels will also increase the risk of infection. In daily life, in addition to personal good hygiene habits, keeping oneself clean and paying attention to clothing, it is also necessary to use some health care products to resist infection. There are many kinds of care products for women on the market, but the current care products lack multiple indicators such as smell, color, use effect and use experience, which is not conducive to improving the acceptance of care products. The particularity of women's care makes certain requirements for these indicators. Summary of the invention
[0003] The present invention aims to provide a female antibacterial liquid, which can take into account multiple indicators such as odor, color, use effect and use experience, so as to improve the acceptance of nursing products.
[0004] To achieve the above objectives, the present invention adopts the following technical solutions:
[0005] Provided is a female antibacterial liquid, which is composed of the following substances in parts by weight:
[0006] Rose extract 9-10.5 parts;
[0007] 4.5-5.5 parts of glycerol;
[0008] 9-11 parts of Vitex agnus-castus extract;
[0009] 4.5-5.5 parts of saffron extract;
[0010] 4.5-5.5 parts of sesame extract;
[0011] 9-11 parts of camellia extract;
[0012] Grape seed extract 9-11 parts;
[0013] 13.5-16 parts of Kacip Fatimah extract;
[0014] 9-11 parts of jasmine extract;
[0015] 9-11 parts of Mangakali extract;
[0016] 9-11 parts of bone glue;
[0017] 0.2-0.3 parts of trichlorohydroxydiphenyl ether.
[0018] Preferably, the female antibacterial liquid is composed of the following materials in parts by weight:
[0019] Rose extract 9.75 parts;
[0020] Glycerin 5 parts;
[0021] 10 parts of Vitex agnus-castus extract;
[0022] Saffron extract 5 parts;
[0023] 5 parts of sesame extract;
[0024] Camellia extract 10 parts;
[0025] Grape seed extract 10 parts;
[0026] Kacip Fatimah extract 15 parts;
[0027] 10 parts of jasmine extract;
[0028] 10 parts of Mangakali extract;
[0029] 10 parts of bone glue skin;
[0030] 0.25 parts of trichlorohydroxydiphenyl ether.
[0031] Preferably, the purity of the rose extract, glycerin, vitex agnus-castus extract, saffron extract, sesame extract, camellia extract, grape seed extract, Kacip Fatimah extract, jasmine extract and Mangacarp extract is not less than 98%; the purity of the bone gelatin and trichlorohydroxy diphenyl ether is not less than 99%.
[0032] Preferably, the rose extract is obtained by extracting rose flowers as raw materials;
[0033] The Vitex agnus-castus extract is obtained by extracting the branches, leaves and flowers of Vitex agnus-castus as raw materials;
[0034] The saffron extract is obtained by extracting saffron as raw material;
[0035] The sesame extract is obtained by extracting saffron as raw material;
[0036] The camellia extract is obtained by extracting saffron as raw material;
[0037] The grape seed extract is obtained by extracting saffron as raw material;
[0038] The Kacip Fatimah extract is obtained by extracting Kacip Fatimah as raw material;
[0039] The jasmine extract is obtained by extracting jasmine flowers as raw materials;
[0040] The Manga Kale extract is obtained by extracting Manga Kale raw materials.
[0041] Preferably, the rose extract, vitex agnus-castus extract, saffron extract, sesame extract, camellia extract, grape seed extract, Kacip Fatimah extract, jasmine extract and Mangakali extract are each extracted by supercritical carbon dioxide extraction.
[0042] The use of the female antibacterial liquid described in any of the above items in the preparation of a care product for inhibiting Escherichia coli, Staphylococcus aureus and Candida albicans.
[0043] Compared with the prior art, the invention has the following beneficial effects: the female antibacterial liquid is composed of rose extract, violet agnus-castus extract, saffron extract, sesame extract, camellia extract, grape seed extract, Kacip Fatimah extract, jasmine extract, philadelphic acid extract, glycerin, bone glue skin and trichlorohydroxy diphenyl ether according to a certain weight ratio, wherein the rose extract, saffron extract, Kacip Fatimah extract and philadelphic acid extract have the effect of adjusting color, the violet agnus-castus extract and the grape seed extract have the effect of preserving, the sesame extract has the effect of adjusting fragrance, the camellia extract and the jasmine extract have the effect of making the product have a light fragrance, the bone glue skin has the effect of anti-inflammatory and promoting skin hyperplasia, and the trichlorohydroxy diphenyl ether has the effect of antibacterial, so that the female antibacterial liquid has suitable smell and color, good use experience, can simultaneously inhibit Escherichia coli, Staphylococcus aureus and Candida albicans, has good antibacterial effect, takes into account multiple indicators, and can improve its acceptance. DETAILED DESCRIPTION
[0044] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.
[0045] In the following examples, the parts without specific conditions were carried out under conventional conditions or conditions recommended by the manufacturer, and the reagents or instruments used without indicating the manufacturer were all conventional products available from the market. In addition, 1 part in the following examples is 1 g.
[0046] Example 1: A female antibacterial liquid
[0047] The female antibacterial liquid is composed of the following materials in parts by weight: 9 parts of rose extract; 4.5 parts of glycerin; 9 parts of vitex agnus-castus extract; 4.5 parts of saffron extract; 4.5 parts of sesame extract; 9 parts of camellia extract; 9 parts of grape seed extract; 13.5 parts of Kacip Fatimah extract; 9 parts of jasmine extract; 9 parts of ramie extract; 9 parts of bone glue skin; 0.2 parts of trichlorohydroxy diphenyl ether. Among them, the purity of rose extract, glycerin, vitex agnus-castus extract, saffron extract, sesame extract, camellia extract, grape seed extract, Kacip Fatimah extract, jasmine extract, and ramie extract in the female antibacterial liquid is not less than 98%; the purity of bone glue skin and trichlorohydroxy diphenyl ether is not less than 99%.
[0048] Some of the functions of various substances in the female antibacterial liquid are as follows: rose extract, saffron extract, Kacip Fatimah extract, and Manga Kale extract have a color-adjusting effect; Vitex agnus-castus extract and grape seed extract have a preservative effect; sesame extract has a perfume-adjusting effect; camellia extract and jasmine extract have a light fragrance for the product; the effect of bone gelatin is anti-inflammatory and promotes skin proliferation; the effect of trichlorohydroxydiphenyl ether is antibacterial.
[0049] The methods of obtaining some substances in the female antibacterial liquid are as follows: rose extract is obtained by extracting rose flowers as raw materials; Vitex agnus-castus extract is obtained by extracting branches, leaves and flowers of Vitex agnus-castus as raw materials; saffron extract is obtained by extracting saffron as raw materials; sesame extract is obtained by extracting saffron as raw materials; camellia extract is obtained by extracting saffron as raw materials; grape seed extract is obtained by extracting saffron as raw materials; Kacip Fatimah extract is obtained by extracting Kacip Fatimah as raw materials; jasmine extract is obtained by extracting jasmine flowers as raw materials; Manga Kali extract is obtained by extracting Manga Kali raw materials. Among them, the extraction methods of rose extract, Vitex agnus-castus extract, saffron extract, sesame extract, camellia extract, grape seed extract, Kacip Fatimah extract, jasmine extract and Manga Kali extract are respectively obtained by supercritical carbon dioxide extraction.
[0050] Taking the extraction of rose extract as an example, the process of using supercritical carbon dioxide extraction is as follows: the rose raw material is dried and crushed, and then placed in an extractor and contacted with a supercritical carbon dioxide fluid. The supercritical carbon dioxide fluid extracts the target compound from the raw material by dissolving it in contact with the raw material, and then the supercritical carbon dioxide fluid in which the target compound is dissolved is transferred to a separator, and the carbon dioxide is converted from a dissolved state to a gaseous state by reducing the pressure or changing the temperature, so that the extracted target compound can be separated. The separated target compound can be recovered by condensation or other methods, and the carbon dioxide can be reused. The extraction method of other extracts in the female antibacterial liquid refers to the extraction method of rose extract, and will not be described one by one here. In addition, according to the properties of each substance, common extraction methods such as solvent extraction and ultrasonic extraction can also be adaptively selected.
[0051] Glycerin, bone glue and trichloroethylene can all be purchased from the market. The CAS number of glycerin is 56-81-5, the CAS number of bone glue is 9000-70-8, and the CAS number of trichloroethylene is 3380-34-5.
[0052] In addition, in some embodiments, rose extract, vitex agnus-castus extract, saffron extract, sesame extract, camellia extract, grape seed extract, Kacip Fatimah extract, jasmine extract, and Manga Kale extract can also be purchased from the market.
[0053] The female antibacterial liquid is prepared by fully mixing the substances in parts by weight.
[0054] The female antibacterial liquid is composed of rose extract, violet aconite extract, saffron extract, sesame extract, camellia extract, grape seed extract, Kacip Fatimah extract, jasmine extract, philadelphic acid extract, glycerin, bone glue, and trichlorohydroxy diphenyl ether according to a certain weight ratio. The rose extract, saffron extract, Kacip Fatimah extract, and philadelphic acid extract have a color adjustment effect, the violet aconite extract and the grape seed extract have a preservative effect, the sesame extract has a perfume adjustment effect, the camellia extract and the jasmine extract have a light fragrance, the bone glue has anti-inflammatory effects and promotes skin hyperplasia, and the trichlorohydroxy diphenyl ether has an antibacterial effect, so that the female antibacterial liquid has a suitable smell and color, a good user experience, and can simultaneously inhibit Escherichia coli, Staphylococcus aureus, and Candida albicans, has a good antibacterial effect, takes into account multiple indicators, and can improve its acceptance.
[0055] Example 2: A female antibacterial liquid
[0056] The female antibacterial liquid is composed of the following materials in parts by weight: 9.75 parts of rose extract; 5 parts of glycerin; 10 parts of vitex agnus-castus extract; 5 parts of saffron extract; 5 parts of sesame extract; 10 parts of camellia extract; 10 parts of grape seed extract; 15 parts of Kacip Fatimah extract; 10 parts of jasmine extract; 10 parts of philadelphica extract; 10 parts of bone glue skin; and 0.25 parts of trichlorohydroxydiphenyl ether.
[0057] The acquisition and preparation methods of the various substances in the female antibacterial liquid in this embodiment can be referred to Example 1, and will not be repeated here.
[0058] Example 3: A female antibacterial liquid
[0059] The female antibacterial liquid is composed of the following materials in parts by weight: 10.5 parts of rose extract; 5.5 parts of glycerin; 11 parts of vitex agnus-castus extract; 5.5 parts of saffron extract; 5.5 parts of sesame extract; 11 parts of camellia extract; 11 parts of grape seed extract; 16 parts of Kacip Fatimah extract; 11 parts of jasmine extract; 11 parts of philadelphica extract; 11 parts of bone glue skin; and 0.3 parts of trichlorohydroxydiphenyl ether.
[0060] The acquisition and preparation methods of the various substances in the female antibacterial liquid in this embodiment can be referred to Example 1, and will not be repeated here.
[0061] The female antibacterial liquid in the above embodiments can be used to prepare a care product that can inhibit Staphylococcus aureus, Escherichia coli, and Candida albicans.
[0062] In order to detect the relevant indicators of the female antibacterial liquid, the following relevant tests were conducted on the female antibacterial liquid:
[0063] Multiple vaginal mucosal irritation test
[0064] The purpose of the multiple vaginal mucosal irritation test is to test the irritation of the female antibacterial liquid to the vaginal mucosa. This test was commissioned by Ingel Testing Technology Service (Shanghai) Co., Ltd. The specific test process and conclusions are as follows:
[0065] 1. Equipment and Animals
[0066] 1. Test samples: Female antibacterial liquid (production batch number: 20220112; maximum application concentration: stock solution), this sample is a female antibacterial liquid with the same weight composition as that in the previous Example 2.
[0067] 2. Animals: 6 Japanese white rabbits, female, weighing 2.0kg to 2.5kg, provided by Beijing Changyang Xishan Breeding Farm, ordinary grade animals, production license number SCXK (Beijing) 2021-0008, quality certificate number 110329221100049623. Feed was provided by Sibeifu (Beijing) Biotechnology Co., Ltd., production license number SCXK (Beijing) 2019-0010, quality certificate number 1103242200082301, animal room temperature 19℃~26℃, relative humidity 40%~70%. 12h lighting, 12h dark. Animals were free to eat and drink water.
[0068] 3. Reagents and instruments: Eosin (Batch No.: 1219A0219), Hematoxylin staining solution (Batch No.: L05N11G1300606), biological microscope (Model: Olympus CX41, Number: DL001), advanced intelligent dehydrator (Model: Leica ASP200S, Number: DL002), paraffin embedding machine (Model: Leica HistoCore Arcadia, Number: DL003), rotary slicer (Model: Leica RM2235, Number: DL007), electronic balance (Model: PL6001E, Number: DL013).
[0069] 2. Methods
[0070] 1. Test basis: Item 2.3.5 of Technical Specifications for Disinfection (2002 edition).
[0071] 2. Preparation of test samples: Use the original test samples.
[0072] 3. Poisoning method: Connect a blunt-tipped hose of about 8 cm in length to a 2 ml syringe. Fill the syringe and catheter with the test sample and set aside. Fix the animal in a supine position, exposing the perineum and vaginal opening. Wet the catheter with the original test sample and gently insert it into the vagina (4 cm to 5 cm), and slowly inject 2 mL of the original test sample with a syringe, then remove the catheter to complete the poisoning. Repeat the poisoning every 24 hours for 5 consecutive days. The animals in the control group were treated with normal saline in the same way.
[0073] 4. Pathological preparation and observation: 24 hours after the last exposure, the animals were killed by gas embolism, and the intact vagina was dissected and observed with the naked eye for pathological changes such as congestion and edema for reference when sampling. Then the vaginal specimen was fixed in 10% formalin solution for more than 24 hours, and tissues from the front, middle and back ends of the vagina were selected for pathological paraffin preparation, HE staining, and pathological light microscopy examination.
[0074] 5. Evaluation indicators: The scoring standards and grading of stimulation intensity refer to Table 2-16 and Table 2-17 in 2.3.5 “Vaginal mucosal irritation test” of the Technical Specifications for Disinfection (2002 edition).
[0075] 3. Results
[0076] 24 hours after the animals were given the test samples or saline, no obvious abnormalities were observed in the clinical observation of the animals, and no obvious abnormalities were observed during the gross examination of the dissected samples. Microscopic observation showed that the front end of the vagina of animal No. 1001 in the control group had very few leukocyte infiltration, epithelial tissue cell degeneration or flattening in the middle end, and epithelial tissue cell degeneration or flattening and very few leukocyte infiltration in the rear end; epithelial tissue cell degeneration or flattening and very few leukocyte infiltration in the front, middle and rear ends of the vagina of animal No. 1002; epithelial tissue cell degeneration or flattening and very few leukocyte infiltration in the front and rear ends of the vagina of animal No. 1003. In the experimental group, the anterior end of the vagina of animal No. 2004 showed epithelial tissue cell degeneration or flattening, very little leukocyte infiltration and very little vascular congestion; the anterior end, middle end and posterior end of the vagina of animal No. 2005 showed epithelial tissue cell degeneration or flattening and very little leukocyte infiltration; the anterior end and posterior end of the vagina of animal No. 2006 showed epithelial tissue cell degeneration or flattening and very little leukocyte infiltration, and the middle end showed epithelial tissue cell degeneration or flattening. Vaginal mucosal irritation reaction score (see Table 1).
[0077] Table 1 Japanese big-eared white rabbit vaginal mucosal irritation test scoring results
[0078]
[0079]
[0080] Note: The reaction score of each part is the sum of the 4 reaction scores. Irritation index = average score of the experimental group - average score of the control group.
[0081] IV. Conclusion
[0082] After testing, The female antibacterial liquid was used in the Japanese white rabbit vaginal mucosal irritation test with the original liquid, and the irritation index was 0.33 (<1), and the intensity of the irritation reaction was none. It met the requirements of the "Technical Specifications for Disinfection" (2002 edition).
[0083] Stability test of trichlorohydroxydiphenyl ether
[0084] The stability test of trichlorohydroxy diphenyl ether is designed to test the stability of trichlorohydroxy diphenyl ether in the female antibacterial solution to ensure its effectiveness during the stable period. This test was commissioned by Ingel Testing Technology Service (Shanghai) Co., Ltd. The specific test process and conclusions are as follows:
[0085] 1. Equipment
[0086] 1. Test samples: Female antibacterial liquid. This sample is a female antibacterial liquid with the same weight composition as that in the previous Example 2.
[0087] 2. BSA124S analytical balance (Sartorius), sensitivity 0.1 mg
[0088] 3.1260Ifinity Agilent HPLC, accuracy +1nm
[0089] 2. Methods
[0090] 1. Test basis: Appendix D of GB / T 27947-2020, Technical Specification for Disinfection (2002 edition) 2.2.3.2.1.
[0091] 2. Test environment temperature 21.5℃, relative humidity 45%
[0092] 3. Results
[0093] After the sample was placed in an environment with a temperature of 37°C for three months, the reduction rate of trichlorohydroxydiphenyl ether content was 3.3%, and the storage period could be determined to be 2 years. The results are listed in Table 2.
[0094] Table 2 Stability test results of trichlorohydroxydiphenyl ether before and after storage
[0095]
[0096] IV. Conclusion
[0097] After the sample was placed in an environment with a temperature of 37°C for three months, the content of trichlorohydroxydiphenyl ether decreased by 3.3%, and the storage period can be set at 2 years.
[0098] Dissolution inhibition test (Escherichia coli, Staphylococcus aureus, Candida albicans)
[0099] The dissolution antibacterial test (Escherichia coli, Staphylococcus aureus, Candida albicans) is designed to detect the antibacterial effect of the female antibacterial liquid on Escherichia coli, Staphylococcus aureus, and Candida albicans. This test was commissioned by Ingel Testing Technology Service (Shanghai) Co., Ltd. The specific test process and conclusions are as follows:
[0100] 1. Equipment
[0101] 1. Test strains: Escherichia coli ATCC 25922, 4th generation; Staphylococcus aureus ATCC 6538, 4th generation; Candida albicans ATCC 10231, 4th generation.
[0102] 2. Test samples: Female antibacterial liquid. This sample is a female antibacterial liquid with the same weight composition as that in the previous Example 2.
[0103] 2. Methods
[0104] 1.Testing basis: GB15979-2002 "Sanitary Standards for Disposable Sanitary Products"
[0105] 2. The test environment temperature is 22℃ and the humidity is 51%
[0106] 3. Test conditions: The test was repeated 3 times.
[0107] 3. Results
[0108] 1. Dissolution inhibition test (Escherichia coli)
[0109] After 3 repeated tests, The inhibition rates of the female antibacterial liquid on Escherichia coli after 2 minutes, 5 minutes, 10 minutes and 20 minutes are shown in Table 3.
[0110] Table 3 Antibacterial effect of female antibacterial liquid on Escherichia coli
[0111]
[0112] 2. Dissolution inhibition test (Staphylococcus aureus)
[0113] After 3 repeated tests, the The inhibition rates of the female antibacterial liquid on Staphylococcus aureus after 2 minutes, 5 minutes, 10 minutes and 20 minutes are shown in Table 4.
[0114] Table 4 Antibacterial effect of female antibacterial liquid on Staphylococcus aureus
[0115]
[0116] 3. Dissolution inhibition test (Candida albicans)
[0117] After 3 repeated tests, the The inhibition rates of the female antibacterial liquid on Candida albicans after 2 minutes, 5 minutes, 10 minutes and 20 minutes are shown in Table 5.
[0118] Table 5 Antibacterial effect of female antibacterial liquid on Candida albicans
[0119]
[0120] IV. Conclusion
[0121] Antibacterial performance test: After three repeated tests, the results showed that the sample had antibacterial effects on Escherichia coli, Staphylococcus aureus and Candida albicans after 2 minutes of exposure, which met the requirements of GB 15979-2002 "Hygiene Standards for Disposable Sanitary Products".
[0122] Total bacterial colonies, coliform bacteria, Pseudomonas aeruginosa, Staphylococcus aureus, hemolytic streptococci, total fungal colonies Number Test
[0123] This test project is designed to detect whether the microbial indicators in the female antibacterial liquid meet the standards. This test was commissioned by Ingel Testing Technology Services (Shanghai) Co., Ltd. The specific test process and conclusions are as follows:
[0124] 1. Equipment
[0125] 1. Test samples: Female antibacterial liquid. This sample is a female antibacterial liquid with the same weight composition as that in the previous Example 2.
[0126] 2. Methods
[0127] 1. Test basis: Appendix B of GB 15979-2002 "Sanitary Standards for Disposable Sanitary Products"
[0128] 2. Test environment temperature 25.3℃, relative humidity 55%
[0129] 3. Results
[0130] Table 6 Microbial index results
[0131]
[0132]
[0133] IV. Conclusion
[0134] The microbiological indicators of the sample all meet the requirements of GB 15979-2002 "Hygiene Standards for Disposable Sanitary Products".
[0135] Lead, arsenic, mercury heavy metal content detection
[0136] 1. Equipment
[0137] 1. Test samples: Female antibacterial liquid. This sample is a female antibacterial liquid with the same weight composition as that in the previous Example 2.
[0138] 2. Instruments and equipment: electronic balance, model BSA124S; microwave digestion instrument, model TOPEX; inductively coupled plasma mass spectrometer (ICP-MS), model NexIon 350X
[0139] 3. Standard solution concentration: Mercury standard solution (1000mg); Arsenic standard solution (1000mg); Lead standard solution (1000mgL)
[0140] 2. Methods
[0141] 1. Testing basis: "Technical Specifications for Safety of Cosmetics" (2015 edition)
[0142] 2. Test environment temperature 19, relative humidity 40%
[0143] 3. Results
[0144] Table 7 Results of determination of lead, arsenic and mercury in female antibacterial liquid
[0145]
[0146] IV. Conclusion
[0147] The lead content of the sample was undetectable (<0.09mg / kg), the arsenic content was undetectable (<0.0033mg / kg), and the mercury content was undetectable (<0.0033mg / kg), which met the requirements.
[0148] It should be noted that, although embodiments of the present invention have been shown and described herein, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to these embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A female antibacterial liquid, characterized in that: The female antibacterial liquid is composed of the following materials in parts by weight: Rose extract 9-10.5 parts; 4.5-5.5 parts of glycerol; 9-11 parts of Vitex agnus-castus extract; 4.5-5.5 parts of saffron extract; 4.5-5.5 parts of sesame extract; 9-11 parts of camellia extract; Grape seed extract 9-11 parts; 13.5-16 parts of Kacip Fatimah extract; 9-11 parts of jasmine extract; 9-11 parts of Mangakali extract; 9-11 parts of bone glue; 0.2-0.3 parts of trichlorohydroxydiphenyl ether.
2. The female antibacterial liquid according to claim 1, characterized in that: The female antibacterial liquid is composed of the following materials in parts by weight: Rose extract 9.75 parts; Glycerin 5 parts; 10 parts of Vitex agnus-castus extract; Saffron extract 5 parts; 5 parts of sesame extract; Camellia extract 10 parts; Grape seed extract 10 parts; Kacip Fatimah extract 15 parts; 10 parts of jasmine extract; 10 parts of Mangakali extract; 10 parts of bone glue skin; 0.25 parts of trichlorohydroxydiphenyl ether.
3. The female antibacterial liquid according to claim 1, characterized in that: The purity of the rose extract, glycerin, vitex agnus-castus extract, saffron extract, sesame extract, camellia extract, grape seed extract, Kacip Fatimah extract, jasmine extract and philadelphica extract is not less than 98%; the purity of the bone gelatin and trichlorohydroxy diphenyl ether is not less than 99%.
4. The female antibacterial liquid according to claim 1, characterized in that: The rose extract is obtained by extracting rose flowers as raw materials; The Vitex agnus-castus extract is obtained by extracting the branches, leaves and flowers of Vitex agnus-castus as raw materials; The saffron extract is obtained by extracting saffron as raw material; The sesame extract is obtained by extracting saffron as raw material; The camellia extract is obtained by extracting saffron as raw material; The grape seed extract is obtained by extracting saffron as raw material; The Kacip Fatimah extract is obtained by extracting Kacip Fatimah as raw material; The jasmine extract is obtained by extracting jasmine flowers as raw materials; The Manga Kale extract is obtained by extracting Manga Kale raw materials.
5. The female antibacterial liquid according to claim 4, characterized in that: The rose extract, vitex agnus-castus extract, saffron extract, sesame extract, camellia extract, grape seed extract, Kacip Fatimah extract, jasmine extract and Mangakali extract are each extracted by a carbon dioxide supercritical extraction method.
6. Use of the female antibacterial liquid according to any one of claims 1 to 5 in the preparation of a care product for inhibiting Escherichia coli, Staphylococcus aureus and Candida albicans.