Oil-control shower gel and preparation method thereof

Abstract

The invention relates to an oil-control shower gel and a preparation method thereof, and relates to the technical field of shower gels. The grease secretion inhibiting factor is obtained by extracting Acai and Gelidium amansii as raw materials according to a weight ratio of (20-25): (3-7). According to the oil-control shower gel disclosed by the invention, the oil secretion inhibiting factor is added, and the oil secretion inhibiting factor is prepared by taking the acai and the gelidium amansii as raw materials in a proper proportion, and the acai and the gelidium amansii are mutually cooperated and jointly act to achieve an effect of regulating oil secretion. The oil-control shower gel not only has a remarkable oil-control effect, but also has multiple good effects of moisturizing, soothing skin and the like, can meet the requirements of vast consumers on fresh and healthy skin, and has a wide market prospect.

Description

Technical Field

[0001] The invention relates to the technical field of shower gel, and in particular to an oil-controlling shower gel and a preparation method thereof. Background Art

[0002] As people's living standards continue to improve, personal cleaning and skin care products are becoming increasingly important in daily life. As one of the most commonly used personal cleaning products, the market demand for shower gel continues to grow, and consumers are increasingly demanding the functionality and safety of shower gel. Traditional shower gel products are mostly used for cleaning and decontamination, but they often contain more chemical ingredients. Long-term use can easily destroy the moisture and oil balance of the skin, leading to dry skin, oily skin and other problems, which is not conducive to skin health.

[0003] There are many types of oil-control shower gels on the market, but most products still cannot fully meet consumers' demand for gentle and effective oil control. The chemical ingredients in these products may irritate sensitive skin, and the oil control effect is not significant enough to fundamentally solve the problem of excessive skin oil secretion. Therefore, developing a new shower gel that can effectively control oil and is gentle and does not irritate the skin has become a technical problem that needs to be solved urgently in the current industry. Summary of the invention

[0004] In order to solve the above problems, the present invention provides an oil-controlling shower gel and a preparation method thereof.

[0005] In a first aspect, the present invention provides an oil-controlling shower gel, wherein the oil-controlling shower gel comprises an oil secretion inhibiting factor;

[0006] The oil secretion inhibitory factor is obtained by extracting acai fruit and Gelidium agar-agar as raw materials in a weight ratio of (20-25):(3-7).

[0007] Furthermore, the preparation method of the oil secretion inhibitory factor comprises the following process:

[0008] The acai fruit and the Gelidium pseudoagar are mixed and crushed, and then added into a solvent for reflux extraction to obtain an extract;

[0009] Concentrating the extract under reduced pressure to obtain an extract;

[0010] The extract is loaded onto a column, and then gradient elution is performed using pure water and an ethanol eluent with a volume fraction of 5 to 95%, and the eluates corresponding to the ethanol eluent with a volume fraction of 25% and the ethanol eluent with a volume fraction of 35% are collected and concentrated under reduced pressure, dried, crushed and sieved to obtain the oil secretion inhibitory factor.

[0011] Furthermore, the solvent includes at least one of water and ethanol with a volume fraction of 5 to 95%; the weight ratio of the total weight of the acai fruit and the agar-agar to the solvent is 1:(5 to 10); and the particle size of the oil secretion inhibitor is 800 to 1000 mesh.

[0012] Furthermore, the volume fraction gradient of the adjacent ethanol eluents is 10%, and the volume of each gradient eluent is 5 to 10 times the column volume.

[0013] Furthermore, the working condition parameters of the reflux extraction include: temperature of 90 to 110° C., time of 60 to 120 minutes, and number of times of 1 to 3 times.

[0014] Furthermore, the oil control shower gel comprises the following components in percentage by weight:

[0015] Surfactant 15-20%, oil secretion inhibitor 0.3-1.5%, sodium chloride 0.05-0.1%, thickener 0.1-0.6%, pH adjuster 0.4-0.8%, chelating agent 0.1-1%, preservative 0.1-1%, humectant 0.2-2%, and the balance is water.

[0016] Furthermore, the oil control shower gel comprises the following components in percentage by weight:

[0017] Surfactant 18%, oil secretion inhibitor 1.0%, sodium chloride 0.08%, thickener 0.4%, pH adjuster 0.5%, chelating agent 0.4%, preservative 0.5%, humectant 1.0%, and the balance is water.

[0018] Furthermore, the surfactant includes at least one of sodium laureth sulfate and cocamidopropyl betaine; the thickener includes PEG-150 distearate; the pH adjuster includes at least one of citric acid and sodium citrate; the chelating agent includes at least one of disodium ethylenediaminetetraacetate and tetrasodium ethylenediaminetetraacetate; the preservative includes p-hydroxyacetophenone; and the humectant includes at least one of glycerin and propylene glycol.

[0019] In a second aspect, the present invention provides a method for preparing the oil-control shower gel according to any one of the first aspects, the preparation method comprising the following steps:

[0020] Obtain oil secretion inhibitory factor;

[0021] The oil secretion inhibitory factor and the remaining components in the oil-controlling shower gel are stirred and mixed to obtain the oil-controlling shower gel.

[0022] The above technical solution provided by the embodiment of the present invention has at least the following advantages compared with the prior art:

[0023] The embodiment of the present invention provides an oil-control shower gel and a preparation method thereof. The oil-control shower gel of the present invention contains an oil secretion inhibitory factor, which is prepared from acai fruit and agar-agar as raw materials in an appropriate proportion. The two cooperate with each other and work together to regulate oil secretion. The oil-control shower gel not only has a significant oil control effect, but also has multiple functions such as good moisturizing and soothing the skin. It can meet the needs of consumers for refreshing and healthy skin and has broad market prospects. Specifically:

[0024] 1) Acai fruit is a natural plant ingredient that can be used as both medicine and food. It is mild and non-irritating. Its extract is rich in active substances such as proanthocyanidins and flavonoids, especially proanthocyanidin dimers, which can effectively inhibit the activity of pancreatic lipase, thereby reducing the production and absorption of oil. At the same time, it is combined with active ingredients such as polysaccharides, polyphenols, and seaweed substances in Gelidium agar to help improve skin barrier function, relieve skin discomfort and tightness caused by excessive oil secretion, reduce the impact of external stimuli on the skin, and further control oil secretion. The two work synergistically and work together to inhibit oil secretion.

[0025] 2) The present invention further uses the obtained oil secretion inhibitor in combination with components such as surfactants to prepare an oil-control shower gel formula, which not only has a significant oil control effect, but also has multiple functions such as good moisturizing and soothing skin; at the same time, the preparation method of the oil-control shower gel is simple, does not require additional specific equipment, and is suitable for mass industrial production.

[0026] Therefore, the present invention is the first to use acai fruit and agar-agar as raw materials in an appropriate proportion to prepare an oil secretion inhibitory factor with the effect of regulating oil secretion, and further use it in combination with components such as surfactants, so that the oil-control shower gel can not only effectively control oil but also maintain the skin's good moisturizing state, soothe the skin, and reduce the dryness and tightness caused by the oil control treatment. It can meet the needs of consumers for refreshed and healthy skin, and bring a new and efficient oil-control skin care option to the market, which has broad market prospects and application value. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the invention and, together with the description, serve to explain the principles of the invention.

[0028] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, for ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative labor.

[0029] Figure 1 The present invention provides a flow chart of a method for preparing an oil-controlling shower gel. DETAILED DESCRIPTION

[0030] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0031] Unless otherwise specified, various raw materials, reagents, instruments and equipment used in the present invention can be purchased from the market or prepared by existing methods.

[0032] In a first aspect, the present invention provides an oil-controlling shower gel, wherein the oil-controlling shower gel comprises an oil secretion inhibiting factor;

[0033] The oil secretion inhibitory factor is obtained by extracting acai fruit and Gelidium agar-agar as raw materials in a weight ratio of (20-25):(3-7).

[0034] The embodiment of the present invention provides an oil-control shower gel, and the oil-control shower gel provided by the present invention contains an oil secretion inhibitory factor, which is prepared from acai fruit and agar-agar as raw materials in an appropriate proportion, and the two cooperate with each other to regulate oil secretion. The oil-control shower gel not only has a significant oil control effect, but also has multiple functions such as good moisturizing and soothing the skin, which can meet the needs of consumers for refreshing and healthy skin, and has broad market prospects. Specifically:

[0035] 1) Acai fruit is a natural plant ingredient that can be used as both medicine and food. It is mild and non-irritating. Its extract is rich in active substances such as proanthocyanidins and flavonoids, especially proanthocyanidin dimers, which can effectively inhibit the activity of pancreatic lipase, thereby reducing the production and absorption of oil. At the same time, it is combined with active ingredients such as polysaccharides, polyphenols, and seaweed substances in Gelidium agar to help improve skin barrier function, relieve skin discomfort and tightness caused by excessive oil secretion, reduce the impact of external stimuli on the skin, and further control oil secretion. The two work synergistically and work together to inhibit oil secretion.

[0036] 2) The present invention further uses the obtained oil secretion inhibitor in combination with components such as surfactants to prepare an oil-control shower gel formula, which not only has a significant oil control effect, but also has multiple functions such as good moisturizing and soothing skin; at the same time, the preparation method of the oil-control shower gel is simple, does not require additional specific equipment, and is suitable for mass industrial production.

[0037] Therefore, the present invention is the first to use acai fruit and agar-agar as raw materials in an appropriate proportion to prepare an oil secretion inhibitory factor with the effect of regulating oil secretion, and further use it in combination with components such as surfactants, so that the oil-control shower gel can not only effectively control oil but also maintain the skin's good moisturizing state, soothe the skin, and reduce the dryness and tightness caused by the oil control treatment. It can meet the needs of consumers for refreshed and healthy skin, and bring a new and efficient oil-control skin care option to the market, which has broad market prospects and application value.

[0038] The acai berry in the present invention, also known as Brazilian berry, comes from the fruit of the acai palm tree (Euterpe oleraceae Mart.) of the palm family. It is a natural plant fruit that is both medicinal and edible, rich in various natural nutrients, including vitamin C, phosphorus, calcium, iron, etc., as well as active substances such as unsaturated fatty acids, vitamin E, phytosterols, flavonoids, polyphenols, anthocyanins, etc.

[0039] The Gelidium acerosa in the present invention is a kind of seaweed, and its main components include polysaccharides, amino acids, vitamins, taurine, choline and other substances with biological activities.

[0040] In some specific embodiments, the weight ratio of the acai fruit to the agar-agar is preferably 23:5.

[0041] In some specific embodiments, the method for preparing the oil secretion inhibitory factor comprises the following process:

[0042] The acai fruit and the Gelidium pseudoagar are mixed and crushed, and then added into a solvent for reflux extraction to obtain an extract;

[0043] Concentrating the extract under reduced pressure to obtain an extract;

[0044] The extract is loaded onto a column, and then gradient elution is performed using pure water and an ethanol eluent with a volume fraction of 5 to 95%, and the eluates corresponding to the ethanol eluent with a volume fraction of 25% and the ethanol eluent with a volume fraction of 35% are collected and concentrated under reduced pressure, dried, crushed and sieved to obtain the oil secretion inhibitory factor.

[0045] In some specific embodiments, the solvent includes at least one of water and 5-95% by volume ethanol, preferably 40% by volume ethanol.

[0046] In some specific embodiments, the weight ratio of the total weight of the acai fruit and the Gelidium agar to the solvent is 1:(5-10); and the particle size of the oil secretion inhibitor is 800-1000 mesh.

[0047] In some specific embodiments, the volume fraction gradient of the adjacent ethanol eluents is 10%, and the volume of each gradient eluent is 5 to 10 times the column volume.

[0048] In some specific embodiments, the working condition parameters of the reflux extraction include: temperature of 90-110° C., time of 60-120 minutes, and number of times of 1-3 times.

[0049] In some specific embodiments, the oil control shower gel comprises the following components by weight percentage:

[0050] Surfactant 15-20%, oil secretion inhibitor 0.3-1.5%, sodium chloride 0.05-0.1%, thickener 0.1-0.6%, pH adjuster 0.4-0.8%, chelating agent 0.1-1%, preservative 0.1-1%, humectant 0.2-2%, and the balance is water.

[0051] In some specific embodiments, the oil control shower gel comprises the following components by weight percentage:

[0052] Surfactant 18%, oil secretion inhibitor 1.0%, sodium chloride 0.08%, thickener 0.4%, pH adjuster 0.5%, chelating agent 0.4%, preservative 0.5%, humectant 1.0%, and the balance is water.

[0053] In some specific embodiments, the surfactant includes at least one of sodium laureth sulfate and cocamidopropyl betaine; the thickener includes PEG-150 distearate; the pH adjuster includes at least one of citric acid and sodium citrate; the chelating agent includes at least one of disodium EDTA and tetrasodium EDTA; the preservative includes p-hydroxyacetophenone; and the humectant includes at least one of glycerin and propylene glycol.

[0054] In a second aspect, based on the same inventive concept, the present invention provides a method for preparing the oil-control shower gel described in any one of the first aspects, such as Figure 1 As shown, the preparation method comprises the following steps:

[0055] Obtain oil secretion inhibitory factor;

[0056] The oil secretion inhibitory factor and the remaining components in the oil-controlling shower gel are stirred and mixed to obtain the oil-controlling shower gel.

[0057] The preparation method of the oil-controlling shower gel provided in the embodiment of the present invention can be carried out according to the existing conventional shower gel preparation method, without the need for additional specific equipment, and is suitable for mass industrial production. At the same time, the preparation method is implemented based on the oil-controlling shower gel described in any one of the first aspects, and therefore has at least the beneficial effects of the oil-controlling shower gel described in any one of the first aspects, which will not be described one by one here.

[0058] In some specific embodiments, the preparation method of the oil-control shower gel comprises the following process:

[0059] The water, surfactant and thickener are stirred and mixed at 50° C., then cooled to 40° C. and the oil secretion inhibitor is added and stirred and mixed continuously, and finally the remaining components are added and stirred and mixed continuously, and cooled to obtain the oil-controlling shower gel.

[0060] It should be noted that the components and raw materials involved in the oil-control shower gel and the preparation method thereof provided by the embodiments of the present invention, unless otherwise specified or specified, can be directly commercially available products or homemade using existing public preparation methods; at the same time, the steps and parameters involved, unless otherwise specified or specified, can be carried out according to the existing processing technology of oil-control shower gel or directly using existing equipment, and the present invention document will not elaborate on them one by one.

[0061] The present invention will be further described below in conjunction with specific examples. It should be understood that these examples are intended only to illustrate the present invention and are not intended to limit the scope of the present invention. The experimental methods in the following examples that do not specify specific conditions are usually measured according to national standards. If there is no corresponding national standard, then the conditions recommended by the manufacturer are followed.

[0062] Example 1

[0063] This example provides a lipid secretion inhibitory factor, which is extracted from acai fruit and Gelidium agar in a weight ratio of 23:5 as raw materials; the preparation method thereof comprises the following steps:

[0064] Step (1): mixing and crushing acai fruit and agar-agar, and then adding 40% ethanol by volume in a ratio of 1:8 of the total weight of the acai fruit and the agar-agar to the weight of the extraction solvent, performing reflux extraction at a temperature of 105° C., a reflux extraction time of 90 minutes, and a reflux extraction number of 2 times, filtering after each reflux extraction to obtain an extract;

[0065] Step (2): The extract obtained in step (1) is concentrated under reduced pressure to obtain a relative density of 1.1 g / cm 3 of extract;

[0066] Step (3): the extract obtained in step (2) is mixed evenly with D101 macroporous resin in a weight ratio of 1:1.2, and the mixture is loaded onto a column by a dry method. Water is first used for elution, and the amount of the eluent used is 8 times the column volume; then, 5% ethanol, 15% ethanol, 25% ethanol, 35% ethanol, 45% ethanol, 55% ethanol, 65% ethanol, 75% ethanol, 85% ethanol and 95% ethanol are used as eluents for gradient elution, and the amount of each gradient eluent is 8 times the column volume. The eluents corresponding to the ethanol eluent with a volume fraction of 25% and the ethanol eluent with a volume fraction of 35% are collected and concentrated under reduced pressure, dried, and crushed through an 800-mesh sieve to obtain the oil secretion inhibitory factor.

[0067] Example 2

[0068] This example provides a lipid secretion inhibitory factor, which is obtained by extracting acai fruit and Gelidium agar-agar at a weight ratio of 20:3 as raw materials; the preparation method thereof comprises the following steps:

[0069] Step (1): mixing and crushing acai fruit and agar-agar, and then adding 40% ethanol by volume in a ratio of 1:8 of the total weight of the acai fruit and the agar-agar to the weight of the extraction solvent, performing reflux extraction at a temperature of 105° C., a reflux extraction time of 90 minutes, and a reflux extraction number of 2 times, filtering after each reflux extraction to obtain an extract;

[0070] Step (2): The extract obtained in step (1) is concentrated under reduced pressure to obtain a relative density of 1.1 g / cm 3 of extract;

[0071] Step (3): the extract obtained in step (2) is mixed evenly with D101 macroporous resin in a weight ratio of 1:1.2, and the mixture is loaded onto a column by a dry method. Water is first used for elution, and the amount of the eluent used is 8 times the column volume; then, 5% ethanol, 15% ethanol, 25% ethanol, 35% ethanol, 45% ethanol, 55% ethanol, 65% ethanol, 75% ethanol, 85% ethanol and 95% ethanol are used as eluents for gradient elution, and the amount of each gradient eluent is 8 times the column volume. The eluents corresponding to the ethanol eluent with a volume fraction of 25% and the ethanol eluent with a volume fraction of 35% are collected and concentrated under reduced pressure, dried, and crushed through an 800-mesh sieve to obtain the oil secretion inhibitory factor.

[0072] Example 3

[0073] This example provides a lipid secretion inhibitory factor, which is extracted from acai fruit and Gelidium agar in a weight ratio of 25:7 as raw materials; the preparation method thereof comprises the following steps:

[0074] Step (1): mixing and crushing acai fruit and agar-agar, and then adding 40% ethanol by volume in a ratio of 1:8 of the total weight of the acai fruit and the agar-agar to the weight of the extraction solvent, performing reflux extraction at a temperature of 105° C., a reflux extraction time of 90 minutes, and a reflux extraction number of 2 times, filtering after each reflux extraction to obtain an extract;

[0075] Step (2): The extract obtained in step (1) is concentrated under reduced pressure to obtain a relative density of 1.1 g / cm 3 of extract;

[0076] Step (3): the extract obtained in step (2) is mixed evenly with D101 macroporous resin in a weight ratio of 1:1.2, and the mixture is loaded onto a column by a dry method. Water is first used for elution, and the amount of the eluent used is 8 times the column volume; then, 5% ethanol, 15% ethanol, 25% ethanol, 35% ethanol, 45% ethanol, 55% ethanol, 65% ethanol, 75% ethanol, 85% ethanol and 95% ethanol are used as eluents for gradient elution, and the amount of each gradient eluent is 8 times the column volume. The eluents corresponding to the ethanol eluent with a volume fraction of 25% and the ethanol eluent with a volume fraction of 35% are collected and concentrated under reduced pressure, dried, and crushed through an 800-mesh sieve to obtain the oil secretion inhibitory factor.

[0077] Example 4

[0078] This example provides a lipid secretion inhibitory factor, which is extracted from acai fruit and Gelidium agar in a weight ratio of 23:5 as raw materials; the preparation method thereof comprises the following steps:

[0079] Step (1): mixing and crushing acai fruit and agar-agar, and then adding them into water in a weight ratio of 1:8 of the total weight of the acai fruit and the agar-agar to the extraction solvent, performing reflux extraction at a temperature of 105° C., a reflux extraction time of 90 minutes, and a reflux extraction number of 2 times, filtering after each reflux extraction to obtain an extract;

[0080] Step (2): The extract obtained in step (1) is concentrated under reduced pressure to obtain a relative density of 1.1 g / cm 3 of extract;

[0081] Step (3): the extract obtained in step (2) is mixed evenly with D101 macroporous resin in a weight ratio of 1:1.2, and the mixture is loaded onto a column by a dry method. Water is first used for elution, and the amount of the eluent used is 8 times the column volume; then, 5% ethanol, 15% ethanol, 25% ethanol, 35% ethanol, 45% ethanol, 55% ethanol, 65% ethanol, 75% ethanol, 85% ethanol and 95% ethanol are used as eluents for gradient elution, and the amount of each gradient eluent is 8 times the column volume. The eluents corresponding to the ethanol eluent with a volume fraction of 25% and the ethanol eluent with a volume fraction of 35% are collected and concentrated under reduced pressure, dried, and crushed through an 800-mesh sieve to obtain the oil secretion inhibitory factor.

[0082] Example 5

[0083] This example provides a lipid secretion inhibitory factor, which is extracted from acai fruit and Gelidium agar in a weight ratio of 23:5 as raw materials; the preparation method thereof comprises the following steps:

[0084] Step (1): mixing and crushing acai fruit and agar-agar, and then adding 95% ethanol by volume in a ratio of 1:8 of the total weight of the acai fruit and the agar-agar to the weight of the extraction solvent, performing reflux extraction at a temperature of 105° C., a reflux extraction time of 90 minutes, and a reflux extraction number of 2 times, filtering after each reflux extraction to obtain an extract;

[0085] Step (2): The extract obtained in step (1) is concentrated under reduced pressure to obtain a relative density of 1.1 g / cm 3 of extract;

[0086] Step (3): the extract obtained in step (2) is mixed evenly with D101 macroporous resin in a weight ratio of 1:1.2, and the mixture is loaded onto a column by a dry method. Water is first used for elution, and the amount of the eluent used is 8 times the column volume; then, 5% ethanol, 15% ethanol, 25% ethanol, 35% ethanol, 45% ethanol, 55% ethanol, 65% ethanol, 75% ethanol, 85% ethanol and 95% ethanol are used as eluents for gradient elution, and the amount of each gradient eluent is 8 times the column volume. The eluents corresponding to the ethanol eluent with a volume fraction of 25% and the ethanol eluent with a volume fraction of 35% are collected and concentrated under reduced pressure, dried, and crushed through an 800-mesh sieve to obtain the oil secretion inhibitory factor.

[0087] Example 6

[0088] This example provides an oil-control shower gel, which comprises the following components in terms of weight percentage:

[0089] Surfactant 18%, oil secretion inhibitor 1.0%, sodium chloride 0.08%, thickener 0.4%, pH adjuster 0.5%, chelating agent 0.4%, preservative 0.5%, humectant 1.0%, balance water;

[0090] The surfactant is composed of sodium laureth sulfate and cocamidopropyl betaine in a weight ratio of 1.5:1;

[0091] The oil secretion inhibitory factor is obtained from Example 1;

[0092] The thickener is PEG-150 distearate;

[0093] The pH regulator is citric acid;

[0094] The chelating agent is disodium ethylenediaminetetraacetate;

[0095] The preservative is p-hydroxyacetophenone;

[0096] The moisturizing agent is composed of glycerol and propylene glycol in a weight ratio of 2:1;

[0097] The water is deionized water.

[0098] The preparation method of the oil-control shower gel comprises the following steps: stirring and mixing water, a surfactant and a thickener at 50° C., then cooling to 40° C. and adding an oil secretion inhibitor and continuing to stir and mix, and finally adding the remaining components and continuing to stir and mix, cooling, to obtain the oil-control shower gel.

[0099] Example 7

[0100] This example provides an oil-control shower gel, which comprises the following components in terms of weight percentage:

[0101] Surfactant 20%, oil secretion inhibitor 0.3%, sodium chloride 0.1%, thickener 0.1%, pH adjuster 0.4%, chelating agent 0.1%, preservative 0.1%, humectant 2.0%, balance water;

[0102] The surfactant is sodium laureth sulfate;

[0103] The oil secretion inhibitory factor is obtained from Example 1;

[0104] The thickener is PEG-150 distearate;

[0105] The pH regulator is citric acid;

[0106] The chelating agent is disodium ethylenediaminetetraacetate;

[0107] The preservative is p-hydroxyacetophenone;

[0108] The moisturizing agent is composed of glycerol and propylene glycol in a weight ratio of 2:1;

[0109] The water is deionized water.

[0110] The preparation method of the above oil-control shower gel is the same as that of Example 6.

[0111] Example 8

[0112] This example provides an oil-control shower gel, which comprises the following components in terms of weight percentage:

[0113] Surfactant 15%, oil secretion inhibitor 1.5%, sodium chloride 0.05%, thickener 0.6%, pH adjuster 0.8%, chelating agent 1%, preservative 1%, moisturizer 0.2%, the balance is water;

[0114] The surfactant is sodium laureth sulfate;

[0115] The oil secretion inhibitory factor is obtained from Example 1;

[0116] The thickener is PEG-150 distearate;

[0117] The pH regulator is citric acid;

[0118] The chelating agent is disodium ethylenediaminetetraacetate;

[0119] The preservative is p-hydroxyacetophenone;

[0120] The moisturizing agent is composed of glycerol and propylene glycol in a weight ratio of 2:1;

[0121] The water is deionized water.

[0122] The preparation method of the above oil-control shower gel is the same as that of Example 6.

[0123] Comparative Example 1

[0124] This example provides a lipid secretion inhibitory factor and a preparation method thereof, which is different from Example 1 only in that the lipid secretion inhibitory factor is extracted from acai fruit and Gelidium agar-agar in a weight ratio of 1:1; the remaining steps and parameters are the same.

[0125] Comparative Example 2

[0126] This example provides a lipid secretion inhibitory factor and a preparation method thereof, which is different from Example 1 only in that: collecting the eluent corresponding to the ethanol eluent with a volume fraction of 75% and the ethanol eluent with a volume fraction of 85%; the remaining steps and parameters are the same.

[0127] The oil secretion inhibitory factor is obtained by extracting acai fruit and Gelidium agar-agar at a weight ratio of 23:5 as raw materials; the preparation method thereof comprises the following steps:

[0128] Step (1): mixing and crushing acai fruit and agar-agar, and then adding 40% ethanol by volume in a ratio of 1:8 of the total weight of the acai fruit and the agar-agar to the weight of the extraction solvent, performing reflux extraction at a temperature of 105° C., a reflux extraction time of 90 minutes, and a reflux extraction number of 2 times, filtering after each reflux extraction to obtain an extract;

[0129] Step (2): The extract obtained in step (1) is concentrated under reduced pressure to obtain a relative density of 1.1 g / cm 3 of extract;

[0130] Step (3): the extract obtained in step (2) is mixed evenly with D101 macroporous resin in a weight ratio of 1:1.2, and the mixture is loaded onto a column by a dry method. Water is first used for elution, and the amount of the eluent used is 8 times the column volume; then, 5% ethanol, 15% ethanol, 25% ethanol, 35% ethanol, 45% ethanol, 55% ethanol, 65% ethanol, 75% ethanol, 85% ethanol and 95% ethanol are used as eluents for gradient elution, and the amount of each gradient eluent is 8 times the column volume. The eluents corresponding to the ethanol eluent with a volume fraction of 75% and the ethanol eluent with a volume fraction of 85% are collected and concentrated under reduced pressure, dried, and crushed through an 800-mesh sieve to obtain the oil secretion inhibitory factor.

[0131] Test Example 1

[0132] In this example, the oil secretion inhibitory factors obtained in the above Examples 1 to 5 and Comparative Examples 1 to 2 were tested for their effectiveness in inhibiting oil secretion by sebaceous gland cells.

[0133] Test method: 1) Human sebaceous gland cells SZ95 in the logarithmic growth phase were used for the experiment. First, the MTT detection experiment based on the human sebaceous gland cells SZ95 cells showed that compared with the solvent control group, when the weight percentage concentration of the test sample was 0.01%, the relative survival rate of the human sebaceous gland cells SZ95 was ≥95%, and it was determined that the 0.01% sample concentration could be used in the subsequent experiment to test the effect of inhibiting the secretion of oil from sebaceous gland cells; 2) The logarithmic growth phase SZ95 cells were digested and counted, and 1×10 4The amount of each was transferred to each sample well of a 96-well plate, and the supernatant was aspirated after incubation for 24 hours, and rinsed once with PBS. Then, according to Table 1 below (note that oleic acid and linoleic acid in Table 1 are stimulants of sebaceous gland cell oil secretion, which can significantly promote the synthesis of neutral lipids in SZ95 cells. The present invention simulates the situation that causes excessive sebum secretion in human skin) 100 μL of the corresponding solution was added, and each group was incubated for 48 hours at 37°C, 5% CO2, and saturated humidity. After incubation for 48 hours, the DMEM complete medium was discarded, carefully rinsed twice with PBS, and 10 μg / mL Nile red was added, and it was left to stand in a dark environment at 37°C for 15 minutes. The released fluorescence was detected with a multifunctional microplate reader with fluorescence function at an excitation wavelength of 485nm and an absorption wavelength of 565nm, with 3 replicates per group. The inhibition rate of the oil control composition on lipid synthesis of SZ95 cells was calculated according to formula (I); the formula (I): lipid inhibition rate (%) = (blank control group OD-test sample group OD) / (blank control group OD)×100%, "OD" stands for optical density (Optical Density), a physical quantity used to measure the degree of absorption of light by a substance.

[0134] The test results are shown in Table 2.

[0135] Table 1

[0136]

[0137] Table 2

[0138] Test samples Lipid inhibition rate (%) Example 1 41.3 Example 2 34.8 Example 3 30.6 Example 4 28.9 Example 5 32.0 Comparative Example 1 9.7 Comparative Example 2 16.4

[0139] It can be seen from Table 2 that, compared with Comparative Examples 1 to 2, the oil secretion inhibitory factors obtained in Examples 1 to 5 of the present invention have a more significant inhibitory effect on the oil secretion of sebaceous gland cells, with the highest inhibition rate reaching 41.3%.

[0140] Test Example 2

[0141] In this example, the oil-control shower gel obtained in Examples 6 to 8 was tested and scored. A total of 30 subjects (the subjects had oily or mixed skin, especially with more oil on the face or back) were randomly divided into 3 groups, and each group tried the oil-control shower gel obtained in Examples 6 to 8. After 2 weeks of use, the subjects scored the product oil control effect (1 to 10 points, the higher the score, the better the effect, the total score is 100 points), the product skin soothing effect (1 to 10 points, the higher the score, the better the effect, the total score is 100 points) and the overall product satisfaction (1 to 10 points, the higher the score, the higher the satisfaction, the total score is 100 points), and the score statistical results are shown in Table 3.

[0142] Table 3

[0143]

[0144] As shown in Table 2, the oil-control shower gel provided by the embodiment of the present invention scored above 85 points in terms of oil control, skin soothing and overall product sensory perception, indicating that the subjects were very satisfied with the product and could meet the needs of consumers for refreshing and healthy skin. At the same time, the subjects said after use that they did not feel any skin irritation or discomfort, nor did they experience any abnormal skin symptoms such as skin redness and acne.

[0145] In summary, the embodiments of the present invention provide an oil-controlling shower gel and a preparation method thereof. For the first time, an oil secretion inhibitory factor with the effect of regulating oil secretion is prepared using acai fruit and agar-agar as raw materials in an appropriate proportion, and is further used in combination with components such as surfactants. The oil-controlling shower gel can effectively control oil while maintaining the skin's good moisturizing state, soothing the skin, and reducing the dryness and tightness caused by the oil control treatment. It can meet the needs of consumers for refreshed and healthy skin, and brings a new and efficient oil-control skin care option to the market, which has broad market prospects and application value.

[0146] Various embodiments of the present invention may be presented in the form of a range; it should be understood that the description in the form of a range is only for convenience and brevity, and should not be understood as a rigid limitation on the scope of the present invention; therefore, the range description should be considered to have specifically disclosed all possible sub-ranges and single numerical values ​​within the range. For example, the range description from 1 to 6 should be considered to have specifically disclosed sub-ranges, such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6, etc., as well as single numbers within the range, such as 1, 2, 3, 4, 5 and 6, which apply regardless of the range. In addition, whenever a numerical range is indicated herein, it is meant to include any cited number (fractional or integer) within the indicated range.

[0147] The foregoing is merely a specific embodiment of the present invention, which enables those skilled in the art to understand or implement the present invention. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but rather to the widest scope consistent with the principles and novel features claimed herein.

Claims

1. An oil-controlling shower gel, characterized in that: The oil-controlling shower gel includes an oil secretion inhibiting factor; The oil secretion inhibitory factor is obtained by extracting acai fruit and Gelidium agar-agar as raw materials in a weight ratio of (20-25):(3-7).

2. The oil-control shower gel according to claim 1, characterized in that: Preparation method of the oil secretion inhibitory factor The process includes: The acai fruit and the Gelidium pseudoagar are mixed and crushed, and then added into a solvent for reflux extraction to obtain an extract; Concentrating the extract under reduced pressure to obtain an extract; The extract is loaded onto a column, and then gradient elution is performed using pure water and an ethanol eluent with a volume fraction of 5 to 95%, and the eluates corresponding to the ethanol eluent with a volume fraction of 25% and the ethanol eluent with a volume fraction of 35% are collected and concentrated under reduced pressure, dried, crushed and sieved to obtain the oil secretion inhibitory factor.

3. The oil-control shower gel according to claim 2, characterized in that: The solvent comprises at least one of water and ethanol with a volume fraction of 5 to 95%; the weight ratio of the total weight of the acai fruit and the agar-agar to the solvent is 1:(5 to 10); and the particle size of the oil secretion inhibitor is 800 to 1000 meshes.

4. The oil-control shower gel according to claim 2, characterized in that: The volume fraction gradient of the adjacent ethanol eluents is 10%, and the volume of each gradient eluent is 5 to 10 times of the column volume.

5. The oil-control shower gel according to claim 2, characterized in that: The working condition parameters of the reflux extraction include: temperature of 90-110° C., time of 60-120 minutes, and number of times of 1-3 times.

6. The oil-control shower gel according to any one of claims 1 to 5, characterized in that: In terms of weight percentage, the oil control shower gel comprises the following components: Surfactant 15-20%, oil secretion inhibitor 0.3-1.5%, sodium chloride 0.05-0.1%, thickener 0.1-0.6%, pH adjuster 0.4-0.8%, chelating agent 0.1-1%, preservative 0.1-1%, humectant 0.2-2%, and the balance is water.

7. The oil-control shower gel according to claim 6, characterized in that: In terms of weight percentage, the oil control shower gel comprises the following components: Surfactant 18%, oil secretion inhibitor 1.0%, sodium chloride 0.08%, thickener 0.4%, pH adjuster 0.5%, chelating agent 0.4%, preservative 0.5%, humectant 1.0%, and the balance is water.

8. The oil-control shower gel according to claim 7, characterized in that: The surfactant includes at least one of sodium laureth sulfate and cocamidopropyl betaine; the thickener includes PEG-150 distearate; the pH adjuster includes at least one of citric acid and sodium citrate; the chelating agent includes at least one of disodium ethylenediaminetetraacetate and tetrasodium ethylenediaminetetraacetate; the preservative includes p-hydroxyacetophenone; and the moisturizer includes at least one of glycerin and propylene glycol.

9. A method for preparing the oil-controlling shower gel according to any one of claims 1 to 8, characterized in that: The preparation method comprises the following steps: Obtain oil secretion inhibitory factor; The oil secretion inhibitor and the remaining components in the oil-controlling shower gel are stirred and mixed to obtain the oil-controlling shower gel.

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