Emblicated capsule movement complete ileum hovering device and method

Abstract

The invention relates to the technical field of intestinal tract treatment, and discloses an edged capsule movement complete ileum hovering device and method, which comprises a peristaltic shell, a driving mechanism is arranged at the tail end of the peristaltic shell, a hovering mechanism is arranged in the peristaltic shell, an administration mechanism is arranged at the head end of the peristaltic shell, and a linkage mechanism is further arranged at the position, close to the administration mechanism, of the peristaltic shell; the driving mechanism is arranged in the wriggling shell, the driving mechanism drives an opposite lantern ring of the hovering mechanism to move oppositely, so that a connecting rod assembly drives a movable assembly to form an opening state, the device hovers at the ileum section, and a linkage mechanism drives the dosing mechanism to form a wriggling state along with the intestinal tract and a hovering continuous dosing state; a patient with the ileitis disease can obtain more accurate and effective treatment, the medicine directly acts on a focus area, and the risk of systemic absorption and adverse reaction is reduced; meanwhile, the continuous administration mode ensures that the effective drug concentration is maintained at the focus part for a long time, and inflammation fading and tissue repairing are facilitated.

Description

Technical Field

[0001] The present invention relates to the technical field of intestinal treatment, and more specifically to a device and method for suspending the whole ileum with an edge sac. Background Art

[0002] In the field of digestive system diseases, ileitis is a chronic nonspecific inflammatory bowel disease, whose lesions are mainly limited to the mucosa and submucosa, and often manifests as recurrent diarrhea, abdominal pain, bloody stools, and tenesmus, which seriously affect the quality of life of patients. At present, the treatment methods for ileitis mainly include drug therapy, surgical treatment, etc., but the traditional drug administration method has problems such as short drug residence time in the intestine, uneven absorption, and difficulty in maintaining effective concentration for a long time, which limits the treatment effect.

[0003] Oral medications need to go through the digestion and absorption process of the stomach and small intestine. Some drugs may become ineffective or destroyed under the action of gastric acid and digestive enzymes, resulting in a decrease in the drug concentration reaching the ileum, affecting the therapeutic effect. Oral medications have a limited residence time in the intestine, and it is difficult to maintain effective drug concentrations for a long time, especially when the intestinal peristalsis is fast, the drugs may be quickly excreted from the body. Oral medications often need to be distributed to various parts of the body through the blood circulation, which not only increases the potential risk of drug damage to normal tissues, but also may cause a series of systemic side effects. The effect of intravenous injection also has the problem of rapid drug metabolism and short duration of action, and has certain treatment risks. Surgical treatment is not only traumatic, but patients need a long recovery period after surgery, and may face the risk of complications such as infection, bleeding, and intestinal obstruction. There is still a possibility of recurrence after surgery, and it cannot be cured. In view of this, we propose a device and method for complete ileal suspension with a marginal sac. Summary of the invention

[0004] The purpose of the present invention is to provide a device and method for suspending the whole ileum with an edge capsule to solve the above technical problems.

[0005] In order to solve the above technical problems, the present invention provides the following technical solutions: a device and method for suspending the whole ileum with edged sac movement, comprising a peristaltic shell, a driving mechanism is arranged at the tail end of the peristaltic shell, a suspension mechanism is arranged inside the peristaltic shell, the suspension mechanism is movably sleeved on the driving mechanism, a drug delivery mechanism is arranged at the head end of the peristaltic shell, and a linkage mechanism is also arranged at a position of the peristaltic shell near the drug delivery mechanism, one end of the linkage mechanism is connected to the driving mechanism, and the other end of the linkage mechanism is connected to the drug delivery mechanism;

[0006] The suspension mechanism comprises a facing collar, a connecting rod assembly and a movable assembly, wherein the facing collar is symmetrically sleeved on the driving mechanism, the connecting rod assembly is hingedly connected to the facing collar in an annular shape with equal spacing, the movable assembly is hingedly connected to one end of the connecting rod assembly away from the facing collar, and the movable assembly is movably inserted into the peristaltic housing;

[0007] The suspension mechanism is driven by a driving mechanism to form a state of following intestinal peristalsis and a state of suspension for continuous drug administration.

[0008] Preferably, the peristaltic shell includes a first shell, a second shell, a middle hole, a support hole, an extended support contact shell and an intestinal flexible chain shell, the middle hole is opened on the first shell and the second shell, the first shell and the second shell are both mounted on the driving mechanism, the driving mechanism is rotatably penetrated on the middle hole, the support holes are opened in a circular shape on the outer walls of the first shell and the second shell at equal intervals and are located at the position of the suspension mechanism, the extended support contact shell is connected to the outer walls of the first shell and the second shell at the position of the support hole, and the intestinal flexible chain shell is connected to the position between the first shell and the second shell.

[0009] Preferably, the driving mechanism includes a micro motor, a first rod, a second rod, a universal joint and opposing external wire grooves, the micro motor is arranged at the tail end of the second outer shell, the first rod is rotatably penetrated through the first outer shell, the second rod is rotatably penetrated through the second outer shell, the universal joint is connected between the first rod and the second rod, and the opposing external wire grooves are opened on the outer walls of the first rod and the second rod.

[0010] Preferably, the hovering mechanism is movably mounted on the first rod body and the second rod body, and the two hovering mechanisms are composed of two groups of forms, one group of the hovering mechanisms is mounted on the first rod body in a cross shape, and the other group of the hovering mechanisms is mounted on the second rod body in an X-shape, so as to jointly realize stable hovering and supporting functions.

[0011] Preferably, the opposing collar comprises a collar body, an opposing inner thread groove and a rotation groove, the collar body is symmetrically sleeved on the driving mechanism, the opposing inner thread groove is opened on the inner wall of the collar body, the rotation groove is opened on the collar body in an annular shape with equal spacing, and the connecting rod assembly is hingedly connected to the rotation groove in an annular shape with equal spacing;

[0012] Wherein, the opposing inner wire grooves and the opposing outer wire grooves are adapted to each other.

[0013] Preferably, the connecting rod assembly includes a first hinge, a second hinge and a movable connecting rod, the first hinge is hingedly connected to the rotating groove in a ring shape with equal intervals, the movable connecting rod is rotatably connected to one end of the first hinge away from the rotating groove, the second hinge is rotatably connected to one end of the movable connecting rod away from the first hinge, and the second hinge is hingedly connected to the movable assembly at one end away from the movable connecting rod.

[0014] Preferably, the movable component includes a movable block, a shaft rod, a movable contact and a rotating hole, the movable block is hingedly connected to the end of the second hinge rod away from the movable connecting rod, the shaft rod is connected to the movable block, the rotating hole is opened on the movable contact, the movable contact is sleeved on the shaft rod through the rotating hole, and the movable contact is movably inserted into the extension support contact shell away from one end of the shaft rod.

[0015] Preferably, the dosing mechanism includes a fixed inner groove, a rotating outer groove, a rotating blade, a fixed rotating shaft, a limiting shaft, a rotating hole, a long hole and an external tooth groove. The fixed inner groove is fixedly connected to the head end of the peristaltic outer shell, the rotating outer groove is rotatably connected to the fixed inner groove, the fixed rotating shaft is arranged in a circular shape with equal intervals on the outer wall of the fixed inner groove, the limiting shaft is arranged in a circular shape with equal intervals on the inner wall of the rotating outer groove, the rotating hole and the long hole are both opened on the rotating blade, one end of the rotating blade is rotatably connected to the fixed rotating shaft through the rotating hole, and the other end of the rotating blade is movably sleeved on the limiting shaft through the long hole, the external tooth groove is opened on the outer wall of the rotating outer groove, and the linkage mechanism is connected to the external tooth groove away from one end connected to the driving mechanism.

[0016] Preferably, the linkage mechanism includes a center gear, a mounting rod, a linkage gear, a sleeve, an inner tooth groove and a ring gear, the center gear is connected to the driving mechanism, the mounting rod is arranged in a ring shape at equal intervals at the head end of the peristaltic shell, the fixed inner groove is fixedly connected to the peristaltic shell through the mounting rod, the linkage gear is rotatably sleeved on one of the mounting rods, the inner tooth groove is opened on the inner wall of one end of the sleeve, the ring gear is arranged on the inner wall of the other end of the sleeve, the inner tooth groove is meshingly connected to the outer tooth groove, and the ring gear is meshingly connected to the linkage gear.

[0017] Preferably, the present invention also provides a method for using a marginal sac-moving complete ileal suspension device, comprising the following steps:

[0018] S1, regulation and inlet operation;

[0019] First, the micro motor is driven to rotate the first rod body. When the first rod body drives the second rod body to rotate through the universal joint, the opposite outer thread grooves symmetrically arranged on the first rod body and the second rod body make the sleeve bodies symmetrically sleeved on the rod bodies move in opposite directions. The two sleeve bodies move in opposite directions to drive the mutually hinged first hinge rod, the second hinge rod and the movable connecting rod to drive the movable block to achieve an inward retraction action, so as to adapt to the narrow passage of the oral cavity and facilitate the patient to easily ingest by oral administration.

[0020] S2, follow the intestinal peristalsis to operate;

[0021] After the device enters the body, since the first shell and the second shell are connected by an intestinal flexible chain shell, and the first rod body and the second rod body are connected by a universal joint, the first shell and the second shell can be bent at will during the peristalsis of the intestine, and naturally move toward the distal end following the peristalsis of the intestine until reaching the target area - the ileum segment;

[0022] S3, external support hovering state control operation;

[0023] The micro motor is driven to rotate the first rod body. When the first rod body drives the second rod body to rotate through the universal joint, the opposite outer thread grooves symmetrically arranged on the first rod body and the second rod body make the ring bodies symmetrically sleeved on the rod bodies move in opposite directions. The two ring bodies move in opposite directions to drive the mutually hinged first hinge rod, the second hinge rod and the movable connecting rod to squeeze the movable block to realize the external support action. When the movable block drives the shaft rod and the movable contact to contact the inner wall of the ileum, since the movable contact is rotatably sleeved on the shaft rod through the rotating hole, the movable contact can adapt to the high and dense annular folds distributed on the surface of the inner wall mucosa layer of the ileum to realize hovering.

[0024] S4, linked continuous drug release operation;

[0025] The central gear is driven to rotate by the rotational driving force of the driving mechanism, and the central gear drives the linkage gear connected to the mounting rod to rotate, and the linkage gear is meshed and connected to the ring gear of the sleeve to drive the sleeve to rotate, and the sleeve causes the inner tooth groove to rotate to drive the outer tooth groove and the rotating outer groove to rotate, and the limiting shaft on the inner wall of the rotating outer groove slides in the long hole at one end of the rotating blade, and the rotating hole at the other end of the rotating blade is rotatably sleeved on the fixed rotating shaft to realize the opening of the four rotating blades, thereby realizing the continuous and stable release of the drug;

[0026] S5, natural discharge;

[0027] After administration, the device is excreted from the body through the natural peristalsis of the intestines and defecation process.

[0028] Compared with the prior art, the present invention has the following beneficial effects:

[0029] 1. The present invention sets a driving mechanism inside the peristaltic housing, and drives the opposing rings of the suspension mechanism to move in opposite directions through the driving mechanism, so that the connecting rod assembly drives the movable assembly to form a stretched state, so that the device is suspended in the ileum segment, and drives the drug delivery mechanism to form a state of following intestinal peristalsis and a suspended continuous drug delivery state through the linkage mechanism, so that patients with ileitis can obtain more accurate and effective treatment. The drug directly acts on the lesion area, reducing the risk of systemic absorption and adverse reactions; at the same time, the continuous drug delivery method ensures that the lesion site maintains an effective drug concentration for a long time, which is conducive to the disappearance of inflammation and tissue repair.

[0030] 2. In the present invention, the shell assembly of the peristaltic shell is provided with two, namely, the first shell and the second shell. When the driving mechanism drives the opposing rings of the suspension mechanism to move toward each other, the connecting rod assembly drives the movable assembly to form an expanded state, and the movable assembly is inserted into the support hole, so that the extended support contact shell is expanded to contact the inner wall of the ileum, so that the whole is suspended. An intestinal flexible chain shell is connected between the first shell and the second shell, so that the first shell and the second shell can be bent at will during the process of intestinal peristalsis, thereby reducing the patient's discomfort during treatment and the sense of foreign matter in the intestine, and preventing the patient from having adverse reactions.

[0031] 3. In the present invention, when the micro motor is driven to rotate the first rod body, and the first rod body drives the second rod body to rotate through the universal joint, the opposite external thread grooves symmetrically arranged on the first rod body and the second rod body make the ring bodies symmetrically sleeved on the rod bodies move in opposite directions, and the two ring bodies move in opposite directions to drive the first hinge rod, the second hinge rod and the movable connecting rod hinged to each other to squeeze the movable block to realize the rising or falling action. When the movable block drives the shaft rod and the movable contact to contact the inner wall of the ileum, since the movable contact is rotatably sleeved on the shaft rod through the rotating hole, the movable contact can adapt to the surface of the inner wall mucosa layer of the ileum with high and dense annular folds, thereby further improving the stability of the internal support suspension of the device.

[0032] 4. In the present invention, when the driving mechanism drives the outer tooth groove and the rotating outer groove to rotate through the linkage mechanism, the limiting shaft on the inner wall of the rotating outer groove slides in the long hole at one end of the rotating blade, and the rotating hole at the other end of the rotating blade is rotatably sleeved on the fixed rotating shaft, thereby realizing the opening and closing actions of the four rotating blades, and realizing the continuous and stable release of the drug, so that the lesion area can maintain an effective drug concentration for a long time. This is especially important for diseases such as ileitis that require long-term treatment. Continuous drug administration helps to control inflammatory reactions, reduce disease recurrence, and may promote the repair and regeneration of intestinal mucosa. In addition, since the drug directly acts on the lesion site, the distribution in the systemic circulation is reduced, and the occurrence of systemic side effects can be significantly reduced.

[0033] 5. In the present invention, the central gear is driven to rotate by the rotational driving force of the driving mechanism, and the central gear drives the linkage gear connected to the mounting rod to rotate. The linkage gear is meshed and connected to the ring teeth of the sleeve, driving the sleeve to rotate. The sleeve causes the internal tooth groove to rotate to drive the drug delivery mechanism to achieve closing and opening actions. In the present invention, the suspension mechanism and the drug delivery mechanism are synchronized through the linkage mechanism. When the device enters the esophagus through the mouth, the device as a whole is inwardly retracted to follow the intestinal peristalsis and the drug delivery mechanism is closed. When the device reaches the ileum segment, the driving mechanism causes the suspension mechanism and the drug delivery mechanism to achieve outward support and opening states synchronously. The linkage not only achieves the synchronization effect, but also makes the device structure simpler, which not only reduces the weight and volume of the equipment, but also may reduce the manufacturing cost and subsequent maintenance costs. The smaller equipment volume, lower noise and vibration also improve patient treatment compliance. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0035] Figure 2 It is a schematic diagram of the internal structure of the present invention;

[0036] Figure 3 It is a schematic diagram of the internal plane structure of the present invention;

[0037] Figure 4 It is a schematic diagram of the cross-sectional structure of the peristaltic housing of the present invention;

[0038] Figure 5 It is a schematic diagram of the structure of the driving mechanism and the suspension mechanism of the present invention;

[0039] Figure 6 It is a schematic diagram of the driving mechanism structure of the present invention;

[0040] Figure 7 It is a schematic diagram of the structure of the suspension mechanism of the present invention;

[0041] Figure 8 It is a schematic diagram of the partially disassembled structure of the suspension mechanism of the present invention;

[0042] Fig. 9 It is a schematic diagram of the structure of the peristaltic housing, the driving mechanism and the linkage mechanism of the present invention;

[0043] Fig.10 For the present invention Fig. 9 A magnified view of the structure at A;

[0044] Fig.11 It is a cross-sectional structural schematic diagram of the drug delivery mechanism and linkage mechanism of the present invention;

[0045] Fig.12 It is a schematic diagram of the disassembled cross-sectional structure of the drug delivery mechanism of the present invention;

[0046] Fig.13 It is a schematic diagram of the suspended continuous drug delivery state of the present invention.

[0047] Description of the numbers in the figure:

[0048] 1. Peristaltic housing; 2. Driving mechanism; 3. Suspension mechanism; 4. Dosing mechanism; 5. Linkage mechanism;

[0049] 101, first shell; 102, second shell; 103, middle hole; 104, support hole; 105, extended support contact; 106, intestinal flexible chain shell;

[0050] 201, micro motor; 202, first rod body; 203, second rod body; 204, universal joint; 205, opposite outer thread groove;

[0051] 301, opposing collar; 302, connecting rod assembly; 303, movable assembly;

[0052] 401, fixed inner groove; 402, rotating outer groove; 403, rotating blade; 404, fixed rotating shaft; 405, limiting shaft; 406, rotating hole; 407, long hole; 408, external tooth groove;

[0053] 501, central gear; 502, mounting rod; 503, linkage gear; 504, sleeve; 505, internal tooth groove; 506, ring gear;

[0054] 3011, collar body; 3012, opposite inner thread groove; 3013, rotation groove;

[0055] 3021, first hinge rod; 3022, second hinge rod; 3023, movable connecting rod;

[0056] 3031. movable block; 3032. shaft rod; 3033. movable contact; 3034. rotating hole. DETAILED DESCRIPTION

[0057] like Figures 1 to 13 As shown, the present invention relates to a peripheral sac-shaped complete ileum suspension device and method, comprising a peristaltic shell 1, a driving mechanism 2 is provided at the tail end of the peristaltic shell 1, a suspension mechanism 3 is provided inside the peristaltic shell 1, the suspension mechanism 3 is movably sleeved on the driving mechanism 2, a medication mechanism 4 is provided at the head end of the peristaltic shell 1, and a linkage mechanism 5 is further provided at a position of the peristaltic shell 1 near the medication mechanism 4, one end of the linkage mechanism 5 is connected to the driving mechanism 2, and the other end of the linkage mechanism 5 is connected to the medication mechanism 4;

[0058] The suspension mechanism 3 includes a facing ring 301, a connecting rod assembly 302 and a movable assembly 303. The facing ring 301 is symmetrically sleeved on the driving mechanism 2. The connecting rod assembly 302 is annular and equidistantly hingedly connected to the facing ring 301. The movable assembly 303 is hingedly connected to one end of the connecting rod assembly 302 away from the facing ring 301. The movable assembly 303 is movably arranged on the peristaltic housing 1.

[0059] The suspension mechanism 3 forms a state of following intestinal peristalsis and a state of suspension and continuous drug administration through the driving mechanism 2.

[0060] The present invention sets a driving mechanism 2 inside the peristaltic housing 1, and drives the opposing rings 301 of the suspension mechanism 3 to move in opposite directions through the driving mechanism 2, so that the connecting rod assembly 302 drives the movable assembly 303 to form a stretched state, so that the device is suspended in the ileum segment, and drives the drug delivery mechanism 4 to form a state of following intestinal peristalsis and a suspended continuous drug delivery state through the linkage mechanism 5, so that patients with ileitis can obtain more accurate and effective treatment. The drug directly acts on the lesion area, reducing the risk of systemic absorption and adverse reactions; at the same time, the continuous drug delivery method ensures that the lesion site maintains an effective drug concentration for a long time, which is conducive to the disappearance of inflammation and the repair of tissues.

[0061] In an embodiment of the present invention, the peristaltic shell 1 includes a first shell 101, a second shell 102, a middle hole 103, a support hole 104, an extended support contact shell 105 and an intestinal flexible chain shell 106. The middle hole 103 is opened on the first shell 101 and the second shell 102. The first shell 101 and the second shell 102 are both mounted on the driving mechanism 2. The driving mechanism 2 is rotatably penetrated on the middle hole 103. The support holes 104 are opened in a circular shape on the outer walls of the first shell 101 and the second shell 102 at equal intervals and are located at the position of the suspension mechanism 3. The extended support contact shell 105 is connected to the outer walls of the first shell 101 and the second shell 102 at the position of the support hole 104. The intestinal flexible chain shell 106 is connected to the position between the first shell 101 and the second shell 102.

[0062] In the present invention, the peristaltic shell 1 is provided with two shell components, namely the first shell 101 and the second shell 102. When the driving mechanism 2 drives the opposing rings 301 of the suspension mechanism 3 to move toward each other, the connecting rod assembly 302 drives the movable assembly 303 to form an expanded state, and the movable assembly 303 is inserted into the supporting hole 104, so that the extended support contact shell 105 is expanded to contact the inner wall of the ileum, so that the whole is suspended. An intestinal flexible chain shell 106 is connected between the first shell 101 and the second shell 102, so that the first shell 101 and the second shell 102 can be bent at will during the process of intestinal peristalsis, thereby reducing the patient's discomfort during treatment and the sense of foreign matter in the intestine, and preventing the patient from having adverse reactions.

[0063] It is worth noting that the first shell 101, the second shell 102, the extension support contact shell 105 and the intestinal flexible chain shell 106 in the present invention are made of biocompatible materials and have good flexibility and expansibility.

[0064] In the embodiment of the present invention, the driving mechanism 2 includes a micro motor 201, a first rod 202, a second rod 203, a universal joint 204 and an opposite outer thread groove 205. The micro motor 201 is arranged at the rear end of the second housing 102, the first rod 202 is rotatably arranged on the first housing 101, the second rod 203 is rotatably arranged on the second housing 102, the universal joint 204 is connected between the first rod 202 and the second rod 203, and the opposite outer thread groove 205 is opened on the outer wall of the first rod 202 and the second rod 203. In the present invention, the driving micro motor 201 drives the first rod 202 to rotate, and the first rod 202 drives the second rod 203 to rotate through the universal joint 204, so that the opposite outer thread groove 205 on the rod drives the suspension mechanism 3 to produce opposite displacement, realizing the structural state of retraction or outward support, corresponding to the formation of the inward retraction state of following intestinal peristalsis and the outward support state of suspension and continuous drug delivery.

[0065] As another embodiment of the present invention, the suspension mechanism 3 is movably mounted on the first rod 202 and the second rod 203. The two suspension mechanisms 3 are composed of two groups of forms, one of which is mounted on the first rod 202 in a cross shape, and the other is mounted on the second rod 203 in an X-shaped cross shape, together realizing stable suspension and support functions. The two groups of suspension mechanisms 3 in the present invention are respectively arranged in a cross shape and an X-shape, and the purpose of such arrangement is to increase the contact area between the suspension mechanism 3 and the inner wall of the ileum when it is supported externally, so as to realize the suspension and support functions more stably.

[0066] The opposing collar 301 includes a collar body 3011, an opposing inner thread groove 3012 and a rotating groove 3013. The collar body 3011 is symmetrically sleeved on the driving mechanism 2. The opposing inner thread groove 3012 is opened on the inner wall of the collar body 3011. The rotating groove 3013 is opened on the collar body 3011 in an annular shape with equal intervals. The connecting rod assembly 302 is hingedly connected to the rotating groove 3013 in an annular shape with equal intervals.

[0067] The inner thread groove 3012 and the outer thread groove 205 are adapted to each other.

[0068] The connecting rod assembly 302 includes a first hinge 3021, a second hinge 3022 and a movable connecting rod 3023. The first hinge 3021 is hingedly connected to the rotating groove 3013 in a ring shape with equal intervals. The movable connecting rod 3023 is rotatably connected to the end of the first hinge 3021 away from the rotating groove 3013. The second hinge 3022 is rotatably connected to the end of the movable connecting rod 3023 away from the first hinge 3021. The end of the second hinge 3022 away from the movable connecting rod 3023 is hingedly connected to the movable assembly 303.

[0069] The movable assembly 303 includes a movable block 3031, a shaft rod 3032, a movable contact 3033 and a rotating hole 3034. The movable block 3031 is hingedly connected to the end of the second hinge rod 3022 away from the movable connecting rod 3023. The shaft rod 3032 is connected to the movable block 3031. The rotating hole 3034 is opened on the movable contact 3033. The movable contact 3033 is sleeved on the shaft rod 3032 through the rotating hole 3034. The movable contact 3033 is movably inserted into the extension support contact shell 105 at one end away from the shaft rod 3032.

[0070] In the present invention, when the driving micro motor 201 drives the first rod body 202 to rotate, and the first rod body 202 drives the second rod body 203 to rotate through the universal joint 204, the opposite outer wire grooves 205 symmetrically arranged on the first rod body 202 and the second rod body 203 make the ring bodies 3011 symmetrically sleeved on the rod bodies move in opposite directions, and the two ring bodies 3011 move in opposite directions to drive the first hinge rod 3021, the second hinge rod 3022 and the movable connecting rod 3023 which are hinged to each other to squeeze the movable block 3031 to realize the rising or falling action. When the movable block 3031 drives the shaft rod 3032 and the movable contact 3033 to contact the inner wall of the ileum, since the movable contact 3033 is rotatably sleeved on the shaft rod 3032 through the rotating hole, the movable contact 3033 can adapt to the surface of the inner wall mucosal layer of the ileum with high and dense annular folds, thereby further improving the stability of the internal support suspension of the device.

[0071] As another embodiment of the present invention, the dosing mechanism 4 includes a fixed inner groove 401, a rotating outer groove 402, a rotating blade 403, a fixed rotating shaft 404, a limiting shaft 405, a rotating hole 406, a long hole 407 and an outer tooth groove 408, the fixed inner groove 401 is fixedly connected to the head end of the peristaltic housing 1, the rotating outer groove 402 is rotatably connected to the fixed inner groove 401, the fixed rotating shaft 404 is arranged in an annular manner and at equal intervals on the outer wall of the fixed inner groove 401, and the limiting shaft 405 is The circular blades 403 are evenly spaced and arranged on the inner wall of the rotating outer groove 402. The rotating hole 406 and the long hole 407 are both provided on the rotating blade 403. One end of the rotating blade 403 is rotatably connected to the fixed rotating shaft 404 through the rotating hole 406. The other end of the rotating blade 403 is movably sleeved on the limiting shaft 405 through the long hole 407. The external tooth groove 408 is provided on the outer wall of the rotating outer groove 402. The linkage mechanism 5 is connected to the external tooth groove 408 at one end away from the driving mechanism 2. In the present invention, when the driving mechanism 2 drives the outer tooth groove 408 and the rotating outer groove 402 to rotate through the linkage mechanism 5, the limiting shaft 405 on the inner wall of the rotating outer groove 402 slides in the long hole 407 at one end of the rotating blade 403, and the rotating hole 406 at the other end of the rotating blade 403 is rotatably sleeved on the fixed rotating shaft 404, thereby realizing the opening and closing actions of the four rotating blades 403, and realizing the continuous and stable release of the drug, so that the lesion area can maintain an effective drug concentration for a long time. This is particularly important for diseases such as ileitis that require long-term treatment. Continuous drug administration helps to control inflammatory reactions, reduce disease recurrence, and may promote the repair and regeneration of intestinal mucosa. In addition, since the drug directly acts on the lesion site, the distribution in the systemic circulation is reduced, and the occurrence of systemic side effects can be significantly reduced.

[0072] As another embodiment of the present invention, the linkage mechanism 5 includes a center gear 501, a mounting rod 502, a linkage gear 503, a sleeve 504, an inner tooth groove 505 and a ring gear 506. The center gear 501 is connected to the driving mechanism 2. The mounting rod 502 is arranged in a ring shape at an equal interval at the head end of the peristaltic shell 1. The fixed inner groove 401 is fixedly connected to the peristaltic shell 1 through the mounting rod 502. The linkage gear 503 is rotatably sleeved on one of the mounting rods 502. The inner tooth groove 505 is opened on the inner wall of one end of the sleeve 504. The ring gear 506 is arranged on the inner wall of the other end of the sleeve 504. The inner tooth groove 505 is meshedly connected to the outer tooth groove 408, and the ring gear 506 is meshedly connected to the linkage gear 503.

[0073] In the present invention, the central gear 501 is driven to rotate by the rotational driving force of the driving mechanism 2, and the central gear 501 drives the linkage gear 503 connected to the mounting rod 502 to rotate, and the linkage gear 503 is meshed and connected to the ring gear 506 of the sleeve 504, driving the sleeve 504 to rotate, and the sleeve 504 causes the inner tooth groove 505 to rotate to drive the drug delivery mechanism 4 to achieve closing and opening actions. In the present invention, the suspension mechanism 3 and the drug delivery mechanism 4 are synchronized through the linkage mechanism 5. When the device enters the esophagus through the oral cavity, the device as a whole is in a state of retraction to follow the intestinal peristalsis and the drug delivery mechanism 4 is closed. When the device reaches the ileum segment, the driving mechanism 2 causes the suspension mechanism 3 and the drug delivery mechanism 4 to synchronize to achieve an outward support and an open state. The linkage not only achieves a synchronization effect, but also makes the device structure simpler, which not only reduces the weight and volume of the device, but also may reduce the manufacturing cost and subsequent maintenance costs. The smaller device volume, lower noise and vibration also improve patient treatment compliance.

[0074] Working principle: This embodiment provides a method for using a peripheral sac-moving complete ileal suspension device, comprising the following steps:

[0075] S1, regulation and inlet operation;

[0076] First, the micro motor 201 is driven to rotate the first rod 202. When the first rod 202 rotates the second rod 203 through the universal joint 204, the symmetrically arranged outer thread grooves 205 on the first rod 202 and the second rod 203 make the collar bodies 3011 symmetrically sleeved on the rod bodies move in opposite directions. The two collar bodies 3011 move in opposite directions to drive the mutually hinged first hinge rod 3021, the second hinge rod 3022 and the movable connecting rod 3023 to drive the movable block 3031 to achieve an inward retraction action, so as to adapt to the narrow passage of the oral cavity and facilitate the patient to easily ingest by oral administration.

[0077] S2, follow the intestinal peristalsis to operate;

[0078] After the device enters the body, since the intestinal flexible chain shell 106 is connected between the first shell 101 and the second shell 102, and the universal joint 204 is connected between the first rod 202 and the second rod 203, the first shell 101 and the second shell 102 can be bent at will during the peristalsis of the intestine, and naturally move toward the distal end following the peristalsis of the intestine until reaching the target area - the ileum segment;

[0079] S3, external support hovering state control operation;

[0080] The micro motor 201 is driven to drive the first rod 202 to rotate, and when the first rod 202 drives the second rod 203 to rotate through the universal joint 204, the opposite outer thread grooves 205 symmetrically arranged on the first rod 202 and the second rod 203 make the ring bodies 3011 symmetrically sleeved on the rod bodies move in opposite directions, and the two ring bodies 3011 move in opposite directions to drive the mutually hinged first hinge rod 3021, the second hinge rod 3022 and the movable connecting rod 3023 to squeeze the movable block 3031 to realize the external support action, when the movable block 3031 drives the shaft rod 3032 and the movable contact 3033 to contact the inner wall of the ileum, because the movable contact 3033 is rotatably sleeved on the shaft rod 3032 through the rotating hole, the movable contact 3033 can adapt to the inner wall mucosal layer of the ileum with high and dense annular folds, so as to realize hovering;

[0081] S4, linked continuous drug release operation;

[0082] The central gear 501 is driven to rotate by the rotational driving force of the driving mechanism 2, and the central gear 501 drives the linkage gear 503 connected to the mounting rod 502 to rotate, and the linkage gear 503 is meshed and connected to the ring gear 506 of the sleeve 504, driving the sleeve 504 to rotate, and the sleeve 504 causes the inner tooth groove 505 to rotate and drive the outer tooth groove 408 and the rotating outer groove 402 to rotate, and the limit shaft 405 on the inner wall of the rotating outer groove 402 slides in the long hole 407 at one end of the rotating blade 403, and the rotating hole 406 at the other end of the rotating blade 403 is rotatably sleeved on the fixed rotating shaft 404, so that the four rotating blades 403 are opened, and the continuous and stable release of the drug is achieved;

[0083] S5, natural discharge;

[0084] After administration, the device is excreted from the body through the natural peristalsis of the intestines and defecation process.

[0085] The embodiments of the present invention disclose preferred embodiments, but are not limited thereto. A person skilled in the art can easily understand the spirit of the present invention based on the above embodiments and make different extensions and changes. However, as long as they do not deviate from the spirit of the present invention, they are all within the protection scope of the present invention.

Claims

1. A complete ileal suspension device with edge capsule, characterized in that: The invention comprises a peristaltic housing (1), wherein a driving mechanism (2) is provided at the rear end of the peristaltic housing (1), a suspension mechanism (3) is provided inside the peristaltic housing (1), and the suspension mechanism (3) is movably sleeved on the driving mechanism (2), a drug delivery mechanism (4) is provided at the head end of the peristaltic housing (1), and a linkage mechanism (5) is further provided at a position of the peristaltic housing (1) close to the drug delivery mechanism (4), one end of the linkage mechanism (5) is connected to the driving mechanism (2), and the other end of the linkage mechanism (5) is connected to the drug delivery mechanism (4); The suspension mechanism (3) comprises a facing ring (301), a connecting rod assembly (302) and a movable assembly (303); the facing ring (301) is symmetrically sleeved on the driving mechanism (2); the connecting rod assembly (302) is hingedly connected to the facing ring (301) in a ring shape with equal spacing; the movable assembly (303) is hingedly connected to one end of the connecting rod assembly (302) away from the facing ring (301); and the movable assembly (303) is movably inserted into the peristaltic housing (1); The suspension mechanism (3) is driven by the driving mechanism (2) to form a state of following intestinal peristalsis and a state of suspension and continuous drug administration.

2. The edged sac-shaped complete ileum suspension device according to claim 1, characterized in that: The peristaltic housing (1) comprises a first housing (101), a second housing (102), a middle hole (103), a supporting hole (104), an extended supporting contact housing (105) and an intestinal flexible chain housing (106); the middle hole (103) is provided on the first housing (101) and the second housing (102); the first housing (101) and the second housing (102) are both sleeved on the driving mechanism (2); the driving mechanism (2) is rotatably penetrated on the middle hole (103); the supporting holes (104) are provided in an annular shape at equal intervals on the outer walls of the first housing (101) and the second housing (102) and are located at the position of the suspension mechanism (3); the extended supporting contact housing (105) is connected to the outer walls of the first housing (101) and the second housing (102) at the position of the supporting hole (104); and the intestinal flexible chain housing (106) is connected to the position between the first housing (101) and the second housing (102).

3. The edged sac-shaped complete ileum suspension device according to claim 2, characterized in that: The driving mechanism (2) comprises a micro motor (201), a first rod (202), a second rod (203), a universal joint (204) and an opposite external thread groove (205); the micro motor (201) is arranged at the rear end of the second housing (102); the first rod (202) is rotatably inserted into the first housing (101); the second rod (203) is rotatably inserted into the second housing (102); the universal joint (204) is connected between the first rod (202) and the second rod (203); and the opposite external thread groove (205) is opened on the outer walls of the first rod (202) and the second rod (203).

4. The edged sac-shaped complete ileum suspension device according to claim 3, characterized in that: The hovering mechanism (3) is movably mounted on the first rod (202) and the second rod (203), and the two hovering mechanisms (3) are composed of two groups of forms, one group of the hovering mechanisms (3) is mounted on the first rod (202) in a cross shape, and the other group of the hovering mechanisms (3) is mounted on the second rod (203) in an X-shape, so as to jointly realize stable hovering and supporting functions.

5. The edged sac-shaped complete ileum suspension device according to claim 4, characterized in that: The opposing collar (301) comprises a collar body (3011), an opposing inner thread groove (3012) and a rotation groove (3013); the collar body (3011) is symmetrically sleeved on the driving mechanism (2); the opposing inner thread groove (3012) is formed on the inner wall of the collar body (3011); the rotation groove (3013) is formed on the collar body (3011) in an annular shape and at equal intervals; the connecting rod assembly (302) is hingedly connected to the rotation groove (3013) in an annular shape and at equal intervals; Wherein, the opposing inner wire grooves (3012) and the opposing outer wire grooves (205) are adapted to each other.

6. The edged sac-shaped complete ileum suspension device according to claim 5, characterized in that: The connecting rod assembly (302) comprises a first hinge rod (3021), a second hinge rod (3022) and a movable connecting rod (3023), wherein the first hinge rod (3021) is hingedly connected to the rotating groove (3013) in a ring-shaped manner with equal intervals, and the movable connecting rod (3023) is rotatably connected to the end of the first hinge rod (3021) away from the rotating groove (3013), the second hinge rod (3022) is rotatably connected to the end of the movable connecting rod (3023) away from the first hinge rod (3021), and the end of the second hinge rod (3022) away from the movable connecting rod (3023) is hingedly connected to the movable assembly (303).

7. The edged sac-shaped complete ileum suspension device according to claim 6, characterized in that: The movable assembly (303) comprises a movable block (3031), a shaft (3032), a movable contact (3033) and a rotating hole (3034); the movable block (3031) is hingedly connected to the end of the second hinge rod (3022) away from the movable connecting rod (3023); the shaft (3032) is connected to the movable block (3031); the rotating hole (3034) is opened on the movable contact (3033); the movable contact (3033) is sleeved on the shaft (3032) through the rotating hole (3034); and the movable contact (3033) is movably inserted into the extension support contact shell (105) at one end away from the shaft (3032).

8. The edged sac-shaped complete ileum suspension device according to claim 7, characterized in that: The drug delivery mechanism (4) comprises a fixed inner groove (401), a rotating outer groove (402), a rotating blade (403), a fixed rotating shaft (404), a limiting shaft (405), a rotating hole (406), a long hole (407) and an outer tooth groove (408), wherein the fixed inner groove (401) is fixedly connected to the head end of the peristaltic housing (1), the rotating outer groove (402) is rotatably connected to the fixed inner groove (401), the fixed rotating shaft (404) is arranged on the outer wall of the fixed inner groove (401) in an annular manner with equal spacing, and the limiting shaft (405) is arranged on the rotating outer wall in an annular manner with equal spacing. On the inner wall of the groove (402), the rotating hole (406) and the long hole (407) are both opened on the rotating blade (403); one end of the rotating blade (403) is rotatably connected to the fixed rotating shaft (404) through the rotating hole (406); the other end of the rotating blade (403) is movably sleeved on the limiting shaft (405) through the long hole (407); the external tooth groove (408) is opened on the outer wall of the rotating outer groove (402); and the linkage mechanism (5) is connected to the external tooth groove (408) away from the end connected to the driving mechanism (2).

9. The edged sac-shaped complete ileum suspension device according to claim 8, characterized in that: The linkage mechanism (5) comprises a central gear (501), a mounting rod (502), a linkage gear (503), a sleeve (504), an inner tooth groove (505) and a ring gear (506); the central gear (501) is connected to the driving mechanism (2); the mounting rod (502) is arranged at an equal interval in a ring shape at the head end of the peristaltic housing (1); the fixed inner groove (401) is fixedly connected to the peristaltic housing (1) through the mounting rod (502); the linkage gear (503) is rotatably sleeved on one of the mounting rods (502); the inner tooth groove (505) is provided on the inner wall of one end of the sleeve (504); the ring gear (506) is provided on the inner wall of the other end of the sleeve (504); the inner tooth groove (505) is meshedly connected to the outer tooth groove (408); and the ring gear (506) is meshedly connected to the linkage gear (503).

10. The method for using the edged sac-shaped complete ileum suspension device according to claim 9, characterized in that: The following steps are involved: S1, regulation and inlet operation; First, the micro motor (201) is driven to drive the first rod (202) to rotate. When the first rod (202) drives the second rod (203) to rotate via the universal joint (204), the opposite outer thread grooves (205) symmetrically arranged on the first rod (202) and the second rod (203) cause the collar bodies (3011) symmetrically sleeved on the rod bodies to move in opposite directions. The two collar bodies (3011) move in opposite directions and drive the mutually hinged first hinge rod (3021), the second hinge rod (3022) and the movable connecting rod (3023) to drive the movable block (3031) to achieve an inward movement, so as to adapt to the narrow passage of the oral cavity and facilitate the patient to easily ingest the drug by oral administration. S2, follow the intestinal peristalsis to operate; After the device enters the body, since the intestinal flexible chain shell (106) is connected between the first shell (101) and the second shell (102), and the universal joint (204) is connected between the first rod (202) and the second rod (203), the first shell (101) and the second shell (102) can be bent at will during the peristalsis of the intestine, and naturally move toward the distal end following the peristalsis of the intestine until reaching the target area, i.e., the ileum segment; S3, external support hovering state control operation; The micro motor (201) is driven to drive the first rod (202) to rotate, and when the first rod (202) drives the second rod (203) to rotate via the universal joint (204), the symmetrically arranged outer thread grooves (205) on the first rod (202) and the second rod (203) cause the collar bodies (3011) symmetrically sleeved on the rod bodies to move in opposite directions, and the two collar bodies (3011) move in opposite directions to drive the mutually hinged first hinge rod (3021) and the second hinge rod (3023) to rotate. The two hinge rods (3022) and the movable connecting rod (3023) squeeze the movable block (3031) to realize the outward support action. When the movable block (3031) drives the shaft rod (3032) and the movable contact (3033) to contact the inner wall of the ileum, since the movable contact (3033) is rotatably sleeved on the shaft rod (3032) through the rotating hole, the movable contact (3033) can adapt to the high and dense annular folds distributed on the surface of the inner wall mucosa layer of the ileum to realize hovering; S4, linked continuous drug release operation; The central gear (501) is driven to rotate by the rotational driving force of the driving mechanism (2), and the central gear (501) drives the linkage gear (503) connected to the mounting rod (502) to rotate. The linkage gear (503) is meshed and connected to the ring gear (506) of the sleeve (504), driving the sleeve (504) to rotate. The sleeve (504) causes the inner tooth groove (505) to rotate and drive the outer tooth groove (408) and the rotating outer groove (402) to rotate. The limiting shaft (405) on the inner wall of the rotating outer groove (402) slides in the long hole (407) at one end of the rotating blade (403), and the rotating hole (406) at the other end of the rotating blade (403) is rotatably sleeved on the fixed rotating shaft (404), so that the four rotating blades (403) are opened, thereby achieving continuous and stable release of the drug. S5, natural discharge; After administration, the device is excreted from the body through the natural peristalsis of the intestines and defecation process.

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