A preparation mold and preparation method of a sample injection fluid mixing sealing cover

Abstract

The present invention provides a preparation mold and a preparation method for a sealing cover for mixing a sample fluid, and relates to the technical field of preparation of a sealing cover in a medical in vitro diagnostic device. The preparation mold comprises an upper mold, a lower mold, an upper insert pin and a lower insert pin. The upper mold is arranged above a cover body, and a pouring channel is arranged on the upper mold; the lower mold is arranged below the cover body, and a pouring cavity for pouring a sealing soft glue liquid is formed between the lower mold and the upper mold; the bottom end of the upper insert pin abuts against the upper surface of a film on the cover body; the top end of the lower insert pin abuts against the lower surface of the film. The present invention can cooperate with the cover body to form a pouring cavity by arranging an upper mold and a lower mold. After pouring the sealing soft glue liquid into the pouring cavity, the cooled sealing soft glue seals and fixes the film on the cover body, so as to achieve the purpose of simultaneously completing the connection between the film and the cover body and the connection between the sealing soft glue and the cover body, so that the overall process from fixing the film on the sealing cover to connecting the sealing cover with the air and liquid path interface is significantly shortened, and the cost is correspondingly reduced.

Description

Technical Field

[0001] The invention relates to the technical field of preparation of sealing covers in medical in vitro diagnostic instruments, and in particular to a preparation mold and a preparation method of a sealing cover for mixing a sampled fluid. Background Art

[0002] Microfluidics and POCT (Point-Of-Care Testing) products have channels for gas or gas circulation, and a film (breathable film or blood filter membrane) with filtering function is usually set at the port of the channel. The film can be fixed to the hole or groove of the sealing cover in the microfluidics or POCT product by heat pressing, laser, ultrasound, etc. However, the sealing cover usually needs to connect the hole and groove after the film is fixed with other devices, such as the gas path interface or liquid path interface of the equipment (hereinafter referred to as the gas and liquid path interface). When connecting, it is necessary to insert or wrap soft glue in the gas and liquid path interface, such as silicone, rubber or other thermoplastic elastomer devices. Such elastic devices need to be processed and formed by independent molds, and then assembled to the gas and liquid path interface when used. Finally, the gas and liquid path interface with elastic devices is connected to the hole or groove with film on the sealing cover.

[0003] The above scheme has a long overall process from fixing the film on the sealing cover to connecting the sealing cover with the gas and liquid interface, and the cost is high. In addition, the connection position between the elastic device and the sealing cover may be loose or offset.

[0004] Therefore, it is necessary to develop a new sealing cover preparation method to solve the above technical problems. Summary of the invention

[0005] The purpose of the present invention is to provide a preparation mold and a preparation method for a sample fluid mixing sealing cover to solve the problems existing in the prior art. By arranging an upper mold and a lower mold, the cover body can cooperate with the cover body to form a casting cavity in the area where the top film of the cover body is located. After the sealing soft glue liquid is poured into the casting cavity, the cooled sealing soft glue seals and fixes the film on the cover body, thereby achieving the purpose of connecting the film to the cover body and connecting the sealing soft glue to the cover body at the same time, so that the overall process from fixing the film on the sealing cover to connecting the sealing cover with the air and liquid path interfaces is significantly shortened, the cost is correspondingly reduced, and the possibility of loosening or displacement of the connection position between the sealing soft glue and the cover body is reduced.

[0006] To achieve the above object, the present invention provides the following solutions:

[0007] A preparation mold for a sample fluid mixing sealing cover, the sealing cover comprising a cover body, a film and a sealing soft glue, the cover body is provided with a through hole, the film is arranged at the through hole, and the sealing soft glue seals and presses the film on the cover body; the preparation mold comprises an upper mold, a lower mold, an upper insert pin and a lower insert pin, the upper mold is arranged above the cover body, and a pouring channel is arranged on the upper mold; the lower mold is arranged below the cover body, the lower mold is sealed and fixed to the upper mold, and a pouring cavity for pouring a sealing soft glue liquid is formed between the lower mold and the upper mold; the pouring cavity is connected with the pouring channel; the upper insert pin passes through the upper mold, and the bottom end of the upper insert pin extends into the pouring cavity and abuts against the upper surface of the film on the cover body; the bottom end edge of the upper insert pin is located on the inner side of the edge of the film; the lower insert pin passes through the lower mold and the through hole on the cover body, and the top end of the lower insert pin extends into the pouring cavity and abuts against the lower surface of the film.

[0008] As an embodiment, the bottom end of the upper insert pin is an annular abutting end, and the annular surface of the annular abutting end abuts against the upper surface of the film.

[0009] As an implementation manner, the radial thickness of the annular abutting end is 1 / 5 to 1 / 4 of the outer radius of the annular abutting end.

[0010] As an embodiment, the diameter of the top end of the lower setting pin is equal to the diameter of the through hole.

[0011] As an embodiment, the lower mold includes a lower base and a lower profile fixed on the lower base, the lower profile is used to be inserted into the inner cavity of the cover body, and the shape and size of the lower profile are adapted to the shape of the inner cavity of the cover body.

[0012] As an embodiment, the upper mold includes an upper base and an upper profile fixed to the bottom of the upper base, and the upper profile is used to be sleeved on the outside of the cover body; the upper profile and the lower profile surround the casting cavity.

[0013] As one embodiment, three upper and three lower setting needles are provided.

[0014] As one embodiment, the upper insert pin is at the same height as the upper mold.

[0015] As one embodiment, the lower insert pin is at the same height as the lower mold.

[0016] The present invention also discloses a method for preparing a sample fluid mixing sealing cover, comprising the following steps:

[0017] The cover body is sleeved on the outer side of the lower profile in the lower mold, and the film is placed at the through hole position of the cover body; the lower inserting pin is inserted into the lower mold, and the top end of the lower inserting pin abuts against the lower surface of the film;

[0018] Sleeve the upper profile in the upper mold on the outer side of the cover body, insert the upper inserting pin into the upper mold, and abut the bottom end of the upper inserting pin against the upper surface of the film;

[0019] The upper mold, the lower mold, the upper insert pin and the lower insert pin are fixed, and a sealing soft glue liquid is poured from a pouring channel in the upper mold;

[0020] After the sealing soft glue liquid is cooled and solidified, the upper mold, the lower mold, the upper insert pin and the lower insert pin are removed to obtain a sealing cover.

[0021] Compared with the prior art, the present invention has the following technical effects:

[0022] The present invention forms a casting cavity in the area where the top film of the cover body is located by arranging an upper mold and a lower mold, and after the sealing soft glue liquid is poured into the casting cavity, the cooled sealing soft glue seals and fixes the film on the cover body, thereby achieving the purpose of connecting the film to the cover body and connecting the sealing soft glue to the cover body at the same time; and the sealing soft glue formed by pouring can directly connect to the air and liquid circuit interfaces, replacing the method of first fixing the film on the cover body, and then arranging the sealing soft glue at the air and liquid circuit interfaces and then connecting the cover body in the prior art, so that the overall process from fixing the film on the sealing cover to connecting the sealing cover with the air and liquid circuit interfaces is significantly shortened, the cost is correspondingly reduced, and the possibility of loosening or displacement of the connection position between the sealing soft glue and the cover body is reduced.

[0023] The present invention utilizes upper and lower inserting pins to contact the film from above and below respectively, which not only enables the poured sealing soft glue to form a soft glue channel connected to the through hole, but also can position the film to avoid displacement of the film during the pouring process and ensure the position accuracy of the film.

[0024] Other technical solutions of the present invention also have the following technical effects:

[0025] The present invention sets the bottom end of the upper insert pin as an annular abutment end, and presses the film through a small annular surface, which can reduce the heat transfer efficiency and heat transfer amount of the high-temperature sealing soft glue liquid to the film through the upper insert pin, and alleviate the wrinkling of the film due to heat. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0027] Figure 1A schematic diagram of the matching structure of a mold for preparing a sealing cover for mixing a sampled fluid and a sealing cover in one embodiment of the present invention (the upper mold is not shown);

[0028] Figure 2 for Figure 1 Schematic diagram of the longitudinal structure;

[0029] Figure 3 for Figure 2 A schematic diagram of the local enlarged structure of the middle area A;

[0030] Figure 4 for Figure 1 Schematic diagram of the explosion structure;

[0031] Figure 5 It is a schematic diagram of the coordination structure of the upper inlay pin, the lower inlay pin, the film and the sealing soft glue;

[0032] Figure 6 for Figure 5 Schematic diagram of the longitudinal structure;

[0033] Figure 7 for Figure 1 A schematic diagram of the structure of the middle shell;

[0034] Figure 8 for Figure 7 Schematic diagram of the longitudinal section structure.

[0035] Description of reference numerals:

[0036] 1. Cover; 2. Film; 3. Sealing soft rubber; 4. Through hole; 5. Lower mold; 6. Upper inlay pin; 7. Lower inlay pin; 8. Lower profile; 9. Lower base. DETAILED DESCRIPTION

[0037] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0038] The purpose of the present invention is to provide a preparation mold and a preparation method for a sample fluid mixing sealing cover to solve the problems existing in the prior art. By arranging an upper mold and a lower mold, the cover body can cooperate with the cover body to form a casting cavity in the area where the top film of the cover body is located. After the sealing soft glue liquid is poured into the casting cavity, the cooled sealing soft glue seals and fixes the film on the cover body, thereby achieving the purpose of connecting the film to the cover body and connecting the sealing soft glue to the cover body at the same time, so that the overall process from fixing the film on the sealing cover to connecting the sealing cover with the air and liquid path interfaces is significantly shortened, the cost is correspondingly reduced, and the possibility of loosening or displacement of the connection position between the sealing soft glue and the cover body is reduced.

[0039] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below with reference to the accompanying drawings and specific embodiments.

[0040] Embodiment 1:

[0041] like Figure 1 to Figure 8 As shown, this embodiment provides a preparation mold for a sample fluid mixing sealing cover. The sealing cover made by the preparation mold is usually sealed and set on a microfluidic or POCT product, including a cover body 1, a film 2 and a sealing soft glue 3; the cover body 1 is a hard material, and a through hole 4 is set on the cover body 1. The through hole 4 is directly opposite to the fluid channel in the microfluidic or POCT product and is used for the outflow of fluid; the top of the through hole 4 is covered with a film 2, and the sealing soft glue 3 seals and presses the film 2 on the cover body 1. The size of the film 2 is larger than the size of the through hole 4 to ensure that the through hole 4 is completely covered. The position where the through hole 4 is set on the cover body 1 can support the film 2. There are usually multiple through holes 4 on the cover body 1, Figure 1 There are three through holes 4 on the cover body 1; the film 2 is in a strip shape and can simultaneously cover the three through holes 4. When the sealing cover is prepared using the preparation mold in this embodiment, the cover body 1 and the film 2 have been formed, and the preparation mold is mainly used to form the sealing soft glue 3 on the cover body 1 while connecting the cover body 1, the film 2, and the sealing soft glue 3 into a whole.

[0042] The preparation mold includes an upper mold, a lower mold 5, an upper insert pin 6 and a lower insert pin 7. The upper mold is arranged above the cover body 1, and a pouring channel is arranged on the upper mold; the lower mold 5 is arranged below the cover body 1, and the lower mold 5 is sealed and fixed with the upper mold while fixing the cover body 1, and the lower mold 5 cooperates with the upper mold to form a pouring cavity for pouring the sealing soft glue liquid; the pouring cavity is connected with the pouring channel. The upper insert pin 6 passes through the upper mold, and the bottom end of the upper insert pin 6 extends into the pouring cavity and abuts against the upper surface of the film 2 pre-placed on the cover body 1; the bottom edge of the upper insert pin 6 is located on the inner side of the edge of the film 2, and will not completely cover the film 2. The edge of the film 2 is exposed in the pouring cavity, so that the sealing soft glue liquid can cover the edge of the film 2 exposed in the pouring cavity, thereby bonding the film 2 and the cover body 1 as a whole. The lower insert pin 7 passes through the lower mold 5 and the through hole 4 on the cover body 1, and the top end of the lower insert pin 7 extends into the pouring cavity and abuts against the lower surface of the film 2.

[0043] Therefore, this embodiment, by setting the upper mold and the lower mold 5, can cooperate with the cover body 1 to form a casting cavity in the area where the top film 2 of the cover body 1 is located. After the sealing soft glue liquid is poured into the casting cavity, the cooled sealing soft glue 3 seals and fixes the film 2 on the cover body 1, thereby achieving the purpose of connecting the film 2 with the cover body 1 and connecting the sealing soft glue 3 with the cover body 1 at the same time; and the sealing soft glue 3 formed by pouring can be directly connected to the gas and liquid circuit interface, replacing the method of first fixing the film 2 on the cover body 1, and then setting the sealing soft glue 3 at the gas and liquid circuit interface and then connecting the cover body 1 in the prior art, so that the overall process from fixing the film 2 on the sealing cover to connecting the sealing cover with the gas and liquid circuit interface is significantly shortened, the cost is correspondingly reduced, and the possibility of loosening or displacement of the connection position between the sealing soft glue 3 and the cover body 1 is reduced. In addition, this embodiment utilizes upper and lower insert pins 6 and 7 to abut against the film 2 from above and below respectively, which not only enables the poured sealing soft glue 3 to form a soft glue channel connected to the through hole 4, but also can position the film 2 to avoid displacement of the film 2 during the pouring process, thereby ensuring the position accuracy of the film 2.

[0044] The shape of the cover body 1 in the sealing cover of this embodiment is generally a square shape, and the upper and lower molds 5 are used to fix the cover body 1 and the shape of the cover body 1 is adapted. When the cover body 1 is in other shapes, the shapes of the upper and lower molds 5 should be changed with the cover body 1. However, designing the structure of the upper and lower molds 5 so that they can enclose a casting cavity is a skill well known to those skilled in the art, and this embodiment will not be described in detail.

[0045] from Figure 2 , Figure 6It can be seen that some of the lower pins 7 do not abut against the lower surface of the film 2. This is because the positions of the through holes 4 on the cover body 1 are not in a straight line, and the shape of the lower pins 7 is not a cylindrical shape with uniform size. Therefore, from a certain cross-sectional perspective, there are indeed cases where the lower pins 7 do not abut against the lower surface of the film 2. However, in fact, the top of the lower pins 7 are in abutment with the lower surface of the film 2. Figure 2~Figure 6 In the embodiment, four insert pins are arranged in the cover body 1 , but only three of them are lower insert pins 7 which abut against the lower surface of the film 2 .

[0046] As one embodiment, the bottom end of the upper insert pin 6 is an annular abutment end, and the annular surface of the annular abutment end abuts against the upper surface of the film 2. The poured sealing soft glue liquid is usually at a high temperature. The upper insert pin 6 and the lower insert pin 7 are usually made of metal materials with excellent thermal conductivity. If the contact area between the upper insert pin 6 and the film 2 is too large, a large amount of heat will be transferred to the film 2 through the upper insert pin 6, which may easily cause the film 2 to wrinkle. In this embodiment, the bottom end of the upper insert pin 6 is set as an annular abutment end, and the film 2 is pressed by a small annular surface, which can reduce the heat transfer efficiency and heat transfer amount to the film 2, and alleviate the wrinkling of the film 2 due to heat. It should be noted that since the lower insert pin 7 directly blocks the through hole 4 on the cover body 1, and the diameter of the through hole 4 is usually much smaller than the diameter of the coating, the top of the lower insert pin 7 does not need to adopt an annular structure.

[0047] As an implementation manner, in this embodiment, the radial thickness of the annular abutting end is 1 / 5 to 1 / 4 of the outer circle radius thereof.

[0048] As one embodiment, the diameter of the top end of the lower setting pin 7 is equal to the diameter of the through hole 4 .

[0049] As an embodiment, the lower mold 5 includes a lower base 9 and a lower profile 8 fixed on the lower base 9 . The lower profile 8 is used to be inserted into the inner cavity of the cover body 1 . The shape and size of the lower profile 8 are adapted to the shape of the inner cavity of the cover body 1 .

[0050] As one embodiment, the upper mold includes an upper base and an upper profile fixed to the bottom of the upper base, the upper profile is used to be sleeved on the outside of the cover body 1; the upper profile and the lower profile 8 cooperate with the cover body 1 to form a casting cavity.

[0051] As an implementation manner, in this embodiment, the number of the upper inserting pins 6 and the lower inserting pins 7 is the same as the number of the through holes 4, that is, three are provided.

[0052] As one embodiment, the upper insert pin 6 is at the same height as the upper mold; and the lower insert pin 7 is at the same height as the lower mold 5 .

[0053] Embodiment 2:

[0054] This embodiment discloses a method for preparing a sample fluid mixing sealing cover, comprising the following steps:

[0055] First, sleeve the cover body 1 on the outer side of the lower profile 8 in the lower mold 5, and place the film 2 at the position of the through hole 4 of the cover body 1; insert the lower inlay pin 7 into the lower mold 5, and the top end of the lower inlay pin 7 abuts against the lower surface of the film 2; sleeve the upper profile in the upper mold on the outer side of the cover body 1, insert the upper inlay pin 6 into the upper mold, and the bottom end of the upper inlay pin 6 abuts against the upper surface of the film 2; fix the upper mold, the lower mold 5, the upper inlay pin 6 and the lower inlay pin 7, and pour the sealing soft glue liquid from the pouring channel in the upper mold; after the sealing soft glue liquid cools and solidifies, remove the upper mold, the lower mold 5, the upper inlay pin 6 and the lower inlay pin 7 to obtain the sealing cover.

[0056] Adaptive changes made according to actual needs are all within the protection scope of the present invention.

[0057] The present invention uses specific examples to illustrate the principles and implementation methods of the present invention. The above examples are only used to help understand the method and core ideas of the present invention. At the same time, for those skilled in the art, according to the ideas of the present invention, there will be changes in the specific implementation methods and application scope. In summary, the content of this specification should not be understood as limiting the present invention.

Claims

1. A mold for preparing a sample fluid mixing sealing cover, characterized in that: The sealing cover comprises a cover body, a film and a sealing soft glue, the cover body is provided with a through hole, the film is arranged at the through hole, and the sealing soft glue seals and presses the film tightly onto the cover body; The mold preparation comprises: An upper mold, the upper mold is arranged above the cover body, and a pouring channel is arranged on the upper mold; A lower mold, the lower mold is arranged below the cover body, the lower mold is sealed and fixed to the upper mold, a pouring cavity for pouring a sealing soft glue liquid is formed between the lower mold and the upper mold; the pouring cavity is communicated with the pouring channel; An upper inserting pin, the upper inserting pin passes through the upper mold, the bottom end of the upper inserting pin extends into the casting cavity and abuts against the upper surface of the film on the cover body; the bottom end edge of the upper inserting pin is located on the inner side of the edge of the film; and a lower inserting pin, wherein the lower inserting pin penetrates the lower mold and the through hole on the cover body, and the top end of the lower inserting pin extends into the casting cavity and abuts against the lower surface of the film.

2. The mold for preparing the injection fluid mixing sealing cover according to claim 1, characterized in that: The bottom end of the upper insert pin is an annular abutting end, and the annular surface of the annular abutting end abuts against the upper surface of the film.

3. The mold for preparing the injection fluid mixing sealing cover according to claim 2, characterized in that: The radial thickness of the annular abutting end is 1 / 5 to 1 / 4 of the outer radius of the annular abutting end.

4. The mold for preparing the injection fluid mixing sealing cover according to claim 1, characterized in that: The top diameter of the lower pin is equal to the diameter of the through hole.

5. The mold for preparing the injection fluid mixing sealing cover according to claim 1, characterized in that: The lower mold includes a lower base and a lower profile fixed on the lower base. The lower profile is used to be inserted into the inner cavity of the cover body. The shape and size of the lower profile are adapted to the shape of the inner cavity of the cover body.

6. The mold for preparing the injection fluid mixing sealing cover according to claim 5, characterized in that: The upper mold includes an upper base and an upper profile fixed to the bottom of the upper base, wherein the upper profile is used for sleeved on the outside of the cover body; the upper profile and the lower profile surround the casting cavity.

7. The mold for preparing the injection fluid mixing sealing cover according to claim 1, characterized in that: The upper and lower inserting needles are both provided with three.

8. The mold for preparing the injection fluid mixing sealing cover according to claim 1, characterized in that: The upper insert pin is at the same height as the upper die.

9. The mold for preparing the injection fluid mixing sealing cover according to claim 1, characterized in that: The lower insert pin is at the same height as the lower mold.

10. A method for preparing a sealing cover for mixing a sample fluid, characterized in that: The mold for preparing the injection fluid mixing sealing cover according to claim 1 is used, and the preparation method comprises the following steps: The cover body is sleeved on the outer side of the lower profile in the lower mold, and the film is placed at the through hole position of the cover body; the lower inserting pin is inserted into the lower mold, and the top end of the lower inserting pin abuts against the lower surface of the film; Sleeve the upper profile in the upper mold on the outer side of the cover body, insert the upper inserting pin into the upper mold, and abut the bottom end of the upper inserting pin against the upper surface of the film; The upper mold, the lower mold, the upper insert pin and the lower insert pin are fixed, and a sealing soft glue liquid is poured from a pouring channel in the upper mold; After the sealing soft glue liquid is cooled and solidified, the upper mold, the lower mold, the upper insert pin and the lower insert pin are removed to obtain a sealing cover.

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