Light-driven flexible intelligent acupuncture auxiliary patch

Abstract

The invention provides a light-driven flexible intelligent acupuncture auxiliary patch which comprises a photothermal conversion layer and a thermal expansion layer, the thermal expansion layer is overlaid on the photothermal conversion layer, the two ends of the thermal expansion layer are coated with acrylate pressure-sensitive adhesive, and through holes are formed between the photothermal conversion layer and the thermal expansion layer; the photothermal conversion layer comprises a BiFeO3 nanowire-carbon nanotube film, and the thermal expansion layer is made of polyamide, polyester fibers, polyurethane fibers or polyvinyl chloride; biFeO3 nanowires in the BiFeO3 nanowire-carbon nanotube film are arranged in parallel and in order, and the acupuncture auxiliary patch can be bent and deformed under the action of illumination. According to the acupuncture and moxibustion auxiliary patch, the two ends of the acupuncture and moxibustion auxiliary patch are attached to the treatment parts of the body of a patient, through irradiation of an infrared physiotherapy instrument, the acupuncture and moxibustion auxiliary patch is heated, deforms and moves towards the skin of the patient, the pressing and qi regulating curative effect is achieved, and uncomfortable symptoms during acupuncture and moxibustion can be relieved; meanwhile, the acupuncture auxiliary patch is heated to achieve the effects of warming channels and expelling cold through hot moxibustion.

Description

Technical Field

[0001] The present invention relates to the technical field of acupuncture treatment, and in particular to a light-driven flexible intelligent acupuncture auxiliary patch. Background Art

[0002] Acupuncture is a traditional Chinese physical therapy method that uses special metal needles to pierce specific acupuncture points on the human body to play the role of dredging meridians and promoting the circulation of qi and blood; hot moxibustion is a method of moxibustion using various heat sources, which can relieve pain and promote blood circulation. In modern clinical treatment, hot moxibustion is often used in conjunction with acupuncture and infrared physical therapy.

[0003] In traditional acupuncture, there is a treatment method of pressing and regulating qi. In the "Golden Needle Fu", it is recorded that "pressing in front makes the qi move in the back; pressing in the back makes the qi move in the front, and the qi moves to the painful area". In modern acupuncture treatment, the operation steps are to press the acupoints above or below the acupoints, which can make the meridian qi move to the painful area, dredge the meridians, and treat various pains.

[0004] The Chinese patent application document with publication number CN216496498U discloses a clinical acupuncture needle heating device, which can adjust the temperature of the needle body during hot moxibustion treatment according to the actual situation of the patient. However, the above solution has a complex structure, a large product volume, can only adjust the temperature of the needle body, cannot locate the hot moxibustion area, and cannot assist doctors in performing the pressing and regulating qi method to treat pain during acupuncture. Summary of the invention

[0005] The technical problem to be solved by the present invention is how to accurately locate the hot moxibustion area and relieve the discomfort symptoms of acupuncture.

[0006] The present invention solves the above technical problems through the following technical means:

[0007] The first aspect of the present invention provides a light-driven flexible intelligent acupuncture auxiliary patch, comprising a photothermal conversion layer and a thermal expansion layer, wherein the photothermal conversion layer is superimposed with a thermal expansion layer, acrylic pressure-sensitive adhesive is coated on both ends of the thermal expansion layer, and a through hole is opened between the photothermal conversion layer and the thermal expansion layer; the photothermal conversion layer comprises a BiFeO3 nanowire-carbon nanotube film, and the thermal expansion layer material comprises polyamide, polyester fiber, polyurethane fiber or polyvinyl chloride; the BiFeO3 nanowires in the BiFeO3 nanowire-carbon nanotube film are arranged in parallel and orderly, and the acupuncture auxiliary patch can bend and deform under the action of light.

[0008] Beneficial effects: After the doctor performs acupuncture on the patient's body, the acupuncture auxiliary patch of the present invention aligns the through hole of the acupuncture auxiliary patch with the acupuncture needle so that the acupuncture auxiliary patch is placed with the needle tip downward, and the two ends of the acupuncture auxiliary patch are attached to the treatment part of the patient's body through acrylic pressure-sensitive adhesive. Through the irradiation of the infrared physiotherapy device, the acupuncture auxiliary patch heats up and deforms to move toward the patient's skin, which has the effect of pressing and regulating qi and can relieve the discomfort symptoms during acupuncture. At the same time, the acupuncture auxiliary patch heats up to have the effect of hot moxibustion, warming the meridians and dispersing cold.

[0009] BiFeO3 nanowires in BiFeO3 nanowire-carbon nanotube film have photostrictive effect, and their relative elongation can reach 10 -5 The telescopic deformation is reversible and the deformation speed is fast. The BiFeO3 nanowires are arranged in parallel and orderly to form a BiFeO3 nanowire film that is assembled in a directional and orderly manner, so that the deformation produced by the BiFeO3 nanowire-carbon nanotube film can be concentrated and amplified. Adding carbon nanotubes to the BiFeO3 nanowires can effectively improve the macroscopic film-forming property and thermal conductivity of the BiFeO3 nanowires. The present invention combines the BiFeO3 nanowire-carbon nanotube film with a thermal expansion film. Due to the different thermal expansion coefficients of the two films, the light-to-heat conversion effect is used to produce asymmetric thermal expansion deformation, so that the acupuncture auxiliary patch produces bending deformation.

[0010] Preferably, the light-to-heat conversion layer further includes a BiFeO3 nanowire-carbon black film, a BiFeO3 nanowire-graphene film or a BiFeO3 nanowire-MXene film.

[0011] The second aspect of the present invention provides a method for preparing the above-mentioned light-driven flexible intelligent acupuncture auxiliary patch, comprising the following steps:

[0012] (1) Dissolving Bi(NO3)3·5H2O and FeCl3 in an acetone solution, adding ammonia water to adjust the pH, centrifuging and washing, and removing the lower precipitate; dissolving the precipitate in a NaOH mineralizer to react and obtain the product BiFeO3 nanowires;

[0013] (2) mixing BiFeO3 nanowires and carbon nanotubes in a certain proportion with an organic solution as a solvent to form a dispersion, dropping the dispersion on a glass substrate, and heating and evaporating the dispersion under an electric field to form a BiFeO3 nanowire-carbon nanotube film;

[0014] (3) dissolving the thermal expansion material in a solvent to prepare a spinning solution, spinning the spinning solution through an electrospinning machine, and depositing the spinning solution on a BiFeO3 nanowire-carbon nanotube film on a glass substrate;

[0015] (4) The double-layer film of step (3) is peeled off from the glass substrate, and a through hole is opened in the middle, and acrylic pressure-sensitive adhesive is coated on both ends of the heat expansion layer to obtain an acupuncture auxiliary patch.

[0016] Preferably, the mass ratio of the BiFeO3 nanowires to the carbon nanotubes is 1:1-2:1.

[0017] Preferably, the electric field strength of the electric field is 2000-10000 V / cm.

[0018] Preferably, the organic solvent is N,N-dimethylformamide or N,N-dimethylacetamide, and the solvent is formic acid.

[0019] Preferably, the heating evaporation temperature is 40°C.

[0020] Preferably, the concentration of the spinning solution is 10-30wt%.

[0021] Preferably, the heat expandable material comprises polyamide, polyester fiber, polyurethane fiber or polyvinyl chloride.

[0022] Preferably, the light-to-heat conversion layer further includes a BiFeO3 nanowire-carbon black film, a BiFeO3 nanowire-graphene film or a BiFeO3 nanowire-MXene film.

[0023] The advantages of the present invention are:

[0024] 1. The acupuncture auxiliary patch of the present invention has a simple structure, is convenient and compact, and is convenient for doctors to actually operate during acupuncture. The acupuncture auxiliary patch of the present invention is irradiated by an infrared physiotherapy device to increase the temperature and achieve the effect of warming the meridians and dispersing the cold, and produces deformation to achieve the effect of pressing and regulating qi and can relieve the discomfort symptoms during acupuncture.

[0025] 2. The BiFeO3 nanowires in the BiFeO3 nanowire-photothermal material film of the present invention have a photostrictive effect and a ps-level response speed, and their stretching deformation is reversible. Therefore, the BiFeO3 nanowire-photothermal material film can make up for the shortcomings of the current flexible driving film based on carbon nanotubes in terms of response speed.

[0026] 3. The BiFeO3 nanowires in the present invention are arranged in parallel and orderly to form a BiFeO3 nanowire-carbon nanotube film that is assembled in a directional and orderly manner, so that the phase deformation produced by the BiFeO3 nanowires can be concentrated and amplified. On the other hand, the thermal expansion layer has a high thermal expansion coefficient. Through the double-layer structure design, the different thermal expansion coefficients between the BiFeO3 nanowire-carbon nanotube film and the thermal expansion layer are used to produce asymmetric thermal expansion deformation through the photothermal conversion effect, so that the acupuncture auxiliary patch produces bending deformation, which has the effect of pressing ventilation and relieving discomfort symptoms. At the same time, carbon nanotubes have excellent thermal conductivity, so that the temperature of the acupuncture auxiliary patch increases under the irradiation of the infrared physiotherapy device, which has the effect of hot moxibustion warming the meridians and dispersing cold. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 This is a schematic diagram of the structure of a light-driven flexible intelligent acupuncture auxiliary patch in an embodiment of the present invention;

[0028] Figure 2 This is a schematic diagram of the light-driven structure of the light-driven flexible intelligent acupuncture auxiliary patch in an embodiment of the present invention;

[0029] Figure 3 Schematic diagram of the preparation of a light-driven flexible intelligent acupuncture auxiliary patch in an embodiment of the present invention;

[0030] Figure 4 Schematic diagram of BiFeO3 nanowire arrangement under the action of an electric field in an embodiment of the present invention;

[0031] Figure 5 This is a physical picture of the light-driven flexible intelligent acupuncture auxiliary patch in an embodiment of the present invention;

[0032] Figure 6 This is a diagram showing the corresponding changes in angle and temperature of the light-driven flexible intelligent acupuncture auxiliary patch in cyclic lighting in Example 1 of the present invention;

[0033] Figure 7 This is a diagram showing the corresponding changes in angle and temperature of the acupuncture auxiliary patch during circulation in Comparative Example 1 of the present invention;

[0034] In the figure: an acupuncture auxiliary patch 1; an acrylic pressure-sensitive adhesive 11; a heat expansion layer 12; a BiFeO3 nanowire-carbon nanotube film 13; a through hole 14; a substrate 2; a conductive glass sheet 3; a wire 4; and a DC high-voltage power supply 5. DETAILED DESCRIPTION

[0035] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described in combination with the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0036] Unless otherwise specified, the test materials and reagents used in the following examples can be obtained from commercial sources.

[0037] If no specific techniques or conditions are specified in the examples, they can be carried out according to the techniques or conditions described in the literature in the art or according to the product instructions.

[0038] Example 1

[0039] like Figure 1As shown in or 5, this embodiment provides a light-driven flexible intelligent acupuncture auxiliary patch 1, including a photothermal conversion layer and a thermal expansion layer 12, the photothermal conversion layer is a BiFeO3 nanowire-carbon nanotube film 13, the BiFeO3 nanowires in the BiFeO3 nanowire-carbon nanotube film 13 are arranged in parallel and orderly, the carbon nanotubes are multi-walled carbon nanotubes, and a thermal expansion layer 12 is superimposed on the surface of the photothermal conversion layer. The thermal expansion layer material is polyamide, and acrylic pressure-sensitive adhesive 11 is coated on both ends of the thermal expansion layer 12, and a through hole 14 is opened between the BiFeO3 nanowire-carbon nanotube film 13 and the thermal expansion layer 12 for passing the acupuncture needle.

[0040] like Figure 2 As shown, when the acupuncture auxiliary patch 1 passes through the acupuncture needle through the through hole 14, the two ends of the acupuncture auxiliary patch 1 are attached to the patient's skin through the acrylic pressure-sensitive adhesive 11. Through the irradiation of the infrared physiotherapy device, the acupuncture auxiliary patch 1 heats up and deforms, and the acupuncture auxiliary patch 1 is concave from the middle to both sides, so that the acupuncture auxiliary patch 1 fits the patient's skin more closely, plays a role in pressing and regulating qi, and can relieve the discomfort symptoms during acupuncture. At the same time, the acupuncture auxiliary patch 1 heats up and plays an effect of hot moxibustion, warming the meridians and dispersing cold.

[0041] Working principle: The BiFeO3 nanowires in the BiFeO3 nanowire-carbon nanotube film 13 of the acupuncture auxiliary patch 1 have a photostrictive effect, and their relative elongation can reach 10 -5 , with a ps-level response speed, and its expansion and contraction deformation is reversible. The BiFeO3 nanowires are arranged in parallel and orderly to form a directional and orderly assembled BiFeO3 nanowire-carbon nanotube film 13, so that the phase deformation produced by the BiFeO3 nanowire-carbon nanotube film 13 can be concentrated and amplified. Adding multi-walled carbon nanotubes to the BiFeO3 nanowires can effectively improve the macroscopic film-forming property and thermal conductivity of the BiFeO3 nanowires. On the other hand, the polyamide film has a high thermal expansion coefficient of 120×10 -6 / K, through a double-layer structure design, using the different thermal expansion coefficients between the BiFeO3 nanowire-carbon nanotube film 13 and the thermal expansion layer 12, an asymmetric thermal expansion deformation is produced through the photothermal conversion effect, so that the acupuncture auxiliary patch 1 produces a bending deformation, which has the effect of pressing ventilation and relieving discomfort symptoms. At the same time, carbon nanotubes have excellent thermal conductivity, so that the temperature of the acupuncture auxiliary patch 1 increases under the irradiation of the infrared therapy device, which has the effect of hot moxibustion, warming the meridians and dispersing cold.

[0042] In this embodiment, the light-driven flexible intelligent acupuncture auxiliary patch 1 is subjected to a cyclic test. The test method is to illuminate the acupuncture auxiliary patch 1 for five seconds and then to be dark for five seconds as a cycle. The test results are as follows: Figure 6 As shown. Figure 6It can be seen that the angle change trend of the acupuncture auxiliary patch 1 in the cycle light corresponds to the temperature, and the acupuncture auxiliary patch can reach the most suitable hot moxibustion temperature range of 45-50°C during the light exposure. As the temperature rises, the bending driving force of the acupuncture auxiliary patch increases, causing the angle to increase; as the temperature decreases, the bending driving force of the acupuncture auxiliary patch decreases, and the angle decreases.

[0043] Example 2

[0044] This embodiment provides a method for preparing the light-driven flexible intelligent acupuncture auxiliary patch 1 of embodiment 1, comprising the following steps:

[0045] (1) 0.15 mol Bi(NO3)3·5H2O and 0.15 mol FeCl3 were dissolved in 20 mL acetone solution and stirred evenly, ammonia water was added to adjust the pH of the solution to 10, and the solution was centrifuged and washed until neutral to remove the lower precipitate; the precipitate was dissolved in 30 mL of 4 M NaOH mineralizer, and loaded into a high-pressure reactor for chemical reaction at a reaction temperature of 180°C and a reaction time of 24 h to obtain a product, and the product was centrifuged, washed, and dried several times to obtain BiFeO3 nanowires.

[0046] (2) Figure 3 As shown, a copper foil tape is attached to a conductive glass sheet 3, and then a wire 4 is fixed to the copper foil with silver paste to form an electrode. A glass substrate 2 is arranged in the middle of the electrode, and the glass substrate 2 has a size of 25 mm×75 mm. A DC high-voltage power supply 5 is connected to apply an external electric field, wherein the electric field strength is 2000 V / cm.

[0047] BiFeO3 nanowires and multi-walled carbon nanotubes were dissolved in N,N-dimethylacetamide at a mass ratio of 1:1 to form a dispersion having a concentration of 6 mg / mL. 3 mL of the dispersion was dropped onto a glass substrate 2, subjected to an electric field for 10 minutes, and dried on a heating platform at 40°C to obtain a BiFeO3 nanowire-carbon nanotube film 13. Figure 4 This is a schematic diagram of the arrangement of BiFeO3 nanowires under the action of a high voltage electric field.

[0048] (3) A certain amount of PA66 particles was dissolved in formic acid to prepare a PA66 spinning solution with a concentration of 20wt%. The PA66 spinning solution was then added to a 10mL syringe with a 26-gauge blunt needle and installed on a pump assembly with a constant propulsion speed of 1mL / h. An electrospinning machine with a fixed voltage of 32kV was used. During the spinning process, the distance from the spinneret to the collector and the platform height were set to 16 and 28cm, respectively, and the electrospun PA66 fibers were directly deposited on the BiFeO3 nanowire-carbon nanotube film 13.

[0049] (4) The double-layer film in step (3) is peeled off from the glass substrate 2 and dried, a circular through hole 14 is opened in the middle of the obtained double-layer film, and acrylic pressure-sensitive adhesive 11 is coated on both ends of the PA66 film to obtain a light-driven flexible intelligent acupuncture auxiliary patch 1.

[0050] Example 3

[0051] This embodiment provides a method for preparing the light-driven flexible intelligent acupuncture auxiliary patch 1 of embodiment 1. The difference between this embodiment and embodiment 2 is that the mass ratio of BiFeO3 nanowires to multi-walled carbon nanotubes is 2:1.

[0052] Comparative Example 1

[0053] This comparative example provides a light-driven flexible intelligent acupuncture auxiliary patch. The difference between this comparative example and Example 1 is that the thermal expansion material is polyimide.

[0054] In this comparative example, a light-driven flexible intelligent acupuncture auxiliary patch is subjected to a cyclic test. The test method is to illuminate the acupuncture auxiliary patch for five seconds and then to be dark for five seconds as a cycle. The test results are as follows: Figure 7 As shown. Figure 7 It can be seen that the angle change trend of the acupuncture auxiliary patch in the cyclic lighting corresponds to the temperature. During the cycle, the angle change and temperature change of the acupuncture auxiliary patch are unstable, and the angle change is much smaller than that of the light-driven flexible intelligent acupuncture auxiliary patch 1 in Example 1, and the driving performance is poor.

[0055] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the same. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that the technical solutions described in the aforementioned embodiments may still be modified, or some of the technical features may be replaced by equivalents. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A light-driven flexible intelligent acupuncture auxiliary patch, characterized in that: It includes a photothermal conversion layer and a thermal expansion layer, the photothermal conversion layer is superimposed with a thermal expansion layer, both ends of the thermal expansion layer are coated with acrylic pressure-sensitive adhesive, and a through hole is opened between the photothermal conversion layer and the thermal expansion layer; the photothermal conversion layer includes a BiFeO3 nanowire-carbon nanotube film, and the thermal expansion layer material includes polyamide, polyester fiber, polyurethane fiber or polyvinyl chloride; the BiFeO3 nanowires in the BiFeO3 nanowire-carbon nanotube film are arranged in parallel and orderly, and the acupuncture auxiliary patch can bend and deform under the action of light.

2. The light-driven flexible intelligent acupuncture auxiliary patch according to claim 1, characterized in that: The light-to-heat conversion layer further includes a BiFeO3 nanowire-carbon black film, a BiFeO3 nanowire-graphene film or a BiFeO3 nanowire-MXene film.

3. The method for preparing a light-driven flexible intelligent acupuncture auxiliary patch according to any one of claims 1 to 2, characterized in that: The following steps are involved: (1) Dissolving Bi(NO3)3·5H2O and FeCl3 in an acetone solution, adding ammonia water to adjust the pH, centrifuging and washing, and removing the lower precipitate; dissolving the precipitate in a NaOH mineralizer to react and obtain the product BiFeO3 nanowires; (2) mixing BiFeO3 nanowires and carbon nanotubes in a certain proportion with an organic solution as a solvent to form a dispersion, dropping the dispersion on a glass substrate, and heating and evaporating the dispersion under an electric field to form a BiFeO3 nanowire-carbon nanotube film; (3) dissolving the thermal expansion layer material in a solvent to prepare a spinning solution, spinning the spinning solution through an electrospinning machine, and depositing the spinning solution on the BiFeO3 nanowire-carbon nanotube film on a glass substrate; (4) The double-layer film of step (3) is peeled off from the glass substrate, and a through hole is opened in the middle, and acrylic pressure-sensitive adhesive is coated on both ends of the heat expansion layer to obtain an acupuncture auxiliary patch.

4. The method for preparing the light-driven flexible intelligent acupuncture auxiliary patch according to claim 3, characterized in that: The mass ratio of the BiFeO3 nanowires to the carbon nanotubes is 1:1-2:

1.

5. The method for preparing the light-driven flexible intelligent acupuncture auxiliary patch according to claim 3, characterized in that: The electric field strength of the electric field is 2000-10000 V / cm.

6. The method for preparing the light-driven flexible intelligent acupuncture auxiliary patch according to claim 3, characterized in that: The organic solvent is N,N-dimethylformamide or N,N-dimethylacetamide, and the solvent is formic acid.

7. The method for preparing the light-driven flexible intelligent acupuncture auxiliary patch according to claim 3, characterized in that: The heating evaporation temperature is 40°C.

8. The method for preparing the light-driven flexible intelligent acupuncture auxiliary patch according to claim 3, characterized in that: The concentration of the spinning solution is 10-30wt%.

9. The method for preparing the light-driven flexible intelligent acupuncture auxiliary patch according to claim 3, characterized in that: The thermal expansion layer material includes polyamide, polyester fiber, polyurethane fiber or polyvinyl chloride.

10. The method for preparing the light-driven flexible intelligent acupuncture auxiliary patch according to claim 3, characterized in that: The light-to-heat conversion layer further includes a BiFeO3 nanowire-carbon black film, a BiFeO3 nanowire-graphene film or a BiFeO3 nanowire-MXene film.

Images