Subpackaging equipment

Abstract

The invention discloses split charging equipment, which is used for split charging of test tubes with bottle caps and bottle bodies, and comprises a base, a tube body control group and a filling control group, the filling control group is fixed on the base; the filling control group comprises a cap screwing device and a filling device, the tube body control group is used for moving test tubes, and the tube body control group can transport the test tubes to the filling position of the filling control group; the tube body control group comprises a fixing device and a transferring device, the fixing device is used for fixing a bottle body of the test tube, and the transferring device is used for moving the test tube to a bottle cap rotating or filling position. According to the split charging equipment, the relative service life of the pipe body control set and the filling control set is prolonged; and meanwhile, the coordination among different assemblies is improved, the probability that the filling control set or the pipe body control set breaks down in the working process is reduced, and the purposes of reducing the equipment failure and improving the working efficiency can be achieved.

Description

Technical Field

[0001] The present application relates to the field of biomedicine, and in particular to a packaging device. Background Art

[0002] Biopharmaceutical products such as cell therapy drugs and gene therapy drugs play an important role in the precision medicine process of major diseases such as malignant tumors, blood diseases, immune system diseases, metabolic diseases, cardiovascular and cerebrovascular diseases, etc. As these drugs enter the clinical production and commercial production stages, the workload of subpackaging and library construction in the field of biopharmaceutical CGT is increasing, and production requires the ability to quickly handle the quantitative subpackaging of cryopreserved tubes in compliance with the requirements of drug production regulations.

[0003] However, during the research process of this application, the inventors found that in the prior art, manual operation is usually adopted when using cryopreservation tubes for packaging. Since the entire packaging process is time-consuming and manual operation is prone to errors, it does not comply with the principle of traceability of drug production. In addition, biologically active substances are prone to reduced activity if the process takes too long. Therefore, the efficiency is low, compliance is easily challenged, and it also has a great impact on product quality. Summary of the invention

[0004] In order to solve the problems existing in the prior art, the present application provides a packaging device.

[0005] In this application, the plane where the upper surface of the base is located is defined as the horizontal plane, the vertical direction perpendicular to the horizontal plane is the z-axis direction; the direction from the test tube tray to the fixed tray is the x-axis direction; the direction perpendicular to the x-axis direction in the horizontal plane is the y-axis direction.

[0006] The specific technical solutions of this application are as follows:

[0007] 1. A packaging device, wherein the packaging device is used to pack a test tube having a bottle cap and a bottle body, the packaging device comprising:

[0008] Base, tube control group and filling control group;

[0009] The filling control group is used to fill the inside of the test tube, and the filling control group is fixed on the base; the filling control group includes a capping device and a filling device, the capping device is used to screw on or off the bottle cap of the test tube, and the filling device is used to fill the test tube;

[0010] The tube body control group is used to move the test tube, and the tube body control group can transport the test tube to the position where the filling control group performs filling; the tube body control group includes a fixing device and a transfer device, the fixing device is used to fix the bottle body of the test tube, and the transfer device is used to move the test tube to the position of rotating the bottle cap or filling.

[0011] 2. According to the packaging equipment described in item 1, the filling control group includes a gantry bracket, the gantry bracket is fixed to the base, and the capping device and the filling device are both arranged on the gantry bracket.

[0012] 3. According to the packaging equipment described in item 2, the filling control group includes an outer cover shell, the interior of the outer cover shell is hollow, and the gantry bracket, the capping device and the filling device are all arranged inside the outer cover shell; the outer cover shell is detachably connected to the base; and an opening is provided on the outer cover shell for the test tube to enter the capping device and the filling device.

[0013] 4. According to the packaging equipment described in any one of items 1 to 3, the capping device includes an electric clamp and a first reciprocating mechanism, the electric clamp can clamp and rotate the bottle cap; the first reciprocating mechanism can drive the electric clamp to move back and forth; preferably, the first reciprocating mechanism can drive the electric clamp to move back and forth in the z-axis direction.

[0014] 5. According to the packaging equipment described in item 4, the electric clamp is provided with a clamp adapted to the size of the bottle cap; two clamps are arranged opposite to each other, the two clamps can move in the direction away from or close to each other, and the two clamps are provided with a knurled structure on two adjacent side surfaces; the clamp is detachably connected to the electric clamp.

[0015] 6. According to the packaging equipment described in item 4, the tube body control group includes a test tube tray, which is used to place the bottle body, and the test tube tray and the fixing device are both fixed on a transfer device, and the transfer device can move the test tube tray and the fixing device to the bottom of the electric clamp.

[0016] 7. According to the packaging equipment described in any one of items 1 to 6, the fixing device includes a fixed tray and a fixed push plate, the fixed tray is provided with a plurality of grooves for placing the bottle bodies, the fixed push plate can push up each bottle body in the groove and fix the bottle body, the fixed push plate is connected to an electric cylinder, and the electric cylinder can drive the fixed push plate to move back and forth; preferably, the electric cylinder can drive the fixed push plate to move along the x-axis direction.

[0017] 8. According to the packaging equipment described in any one of items 1 to 7, the transfer device includes an electric slide arranged on a base, the electric slide is provided with a mobile platform slidably connected to the base, the electric slide can drive the mobile platform to move back and forth, and the fixing device and the fixed tray are both arranged on the mobile platform; preferably, the electric slide can drive the mobile platform to move back and forth along the x-axis.

[0018] 9. According to the packaging equipment described in item 2, a second reciprocating mechanism is arranged on the gantry bracket, and the second reciprocating mechanism is respectively connected to the filling device and the capping device, and the second reciprocating mechanism can drive the filling device and the capping device to move reciprocatingly. Preferably, the second reciprocating mechanism can drive the filling device and the capping device to move reciprocatingly along the y-axis.

[0019] 10. According to the packaging equipment described in item 2, the second reciprocating mechanism includes a guide rail fixed on the gantry bracket and a guide rail platform slidably connected to the guide rail, the capping device and the filling device are both fixed to the guide rail platform, and a servo motor is arranged on the gantry bracket, and the output shaft of the servo motor is threadedly connected to the guide rail platform using a screw.

[0020] 11. According to the filling equipment described in any one of items 1 to 10, the filling device includes a third reciprocating mechanism, an injection head and a peristaltic pump, one end of the peristaltic pump is connected to the injection head, the injection head is arranged on the third reciprocating mechanism, and the third reciprocating mechanism can drive the injection head to move back and forth to realize filling into the test tube; preferably, the third reciprocating mechanism can drive the injection head to move back and forth along the z-axis direction.

[0021] Beneficial Effects

[0022] The present application provides a filling device, which is used to fill liquid into a test tube, wherein a filling control group is used to fill the test tube, and for a test tube with a bottle cap, the filling control group can also unscrew the bottle cap from the bottle body, and then fill the bottle body, and then screw the unscrewed bottle cap onto the filled bottle body, thereby completing the filling of the test tube.

[0023] The tube body control group is used to transfer test tubes. Test tubes that need to be filled need to be placed on the test tube tray first, and then the tube body control group will drive the test tubes to move on the base. When the test tubes move along the x-axis on the base, they will be accurately moved to the rotating bottle cap or filling position of the filling control group. In this way, the filling control group only needs to move up and down, and the movement of the test tube can be completed by the tube body control group, reducing the workload of a single component of the filling control group or the tube body control group during the filling process, and reducing the workload gap between the filling control group and the tube body control group. On the one hand, since the workload of a single component has been reduced accordingly, the relative service life of the tube body control group and the filling control group has been improved. On the other hand, since the workload in the test tube filling process is evenly distributed to different components, the probability of failure of the filling control group or the tube body control group during work is further reduced, and at the same time, the coordination between different components is improved, which can reduce equipment failure and improve work efficiency.

[0024] In the present application, the capping device and the filling device are fixed to the base using a gantry bracket. Therefore, when the capping device and the filling device are rotating the bottle caps and filling the test tubes, the fixation of the gantry bracket on the base makes the capping device and the filling device more stable, reducing the possibility of misalignment of the capping device and the filling device. At the same time, due to the stability of the fixed connection, the accuracy of the capping device and the filling device during operation is further improved, thereby improving the working efficiency of the filling equipment during filling.

[0025] It is worth mentioning that in this application, both the capping device and the filling device are fixed to the base using a gantry bracket, so when the test tube is rotated and filled, the test tube is located below the gantry bracket fixed to the base. Importantly, before and after the test tube is filled, the bottle body is sealed by the bottle cap, so in this application, an outer cover shell is used to cover the gantry bracket and the capping device and filling device located on the gantry bracket. The outer cover shell can protect its internal components, reduce the possibility of the test tube being affected by the outside world when the bottle cap is unscrewed for filling, and thus reduce the possibility of the bottle body being contaminated when the bottle cap is unscrewed for filling, further improve the safety of test tube filling and the purity of the filled solution, and improve the working efficiency of filling. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 It is a schematic diagram of the overall structure of the packaging equipment of this application;

[0027] Figure 2 This is the structural installation diagram of the filling control group of this application;

[0028] Figure 3 It is a schematic diagram of the filling control group structure of this application;

[0029] Figure 4 It is an exploded view of the pipe body control group of this application.

[0030] In the figure, 1. base; 11. bottle body; 12. bottle cap; 2. filling control group; 21. gantry bracket; 22. outer cover shell; 3. capping device; 31. first reciprocating structure; 32. electric gripper; 4. filling device; 41. third reciprocating mechanism; 42. injection head; 43. peristaltic pump; 5. tube body control group; 51. test tube tray; 6. fixing device; 61. fixed tray; 62. fixed push plate; 63. electric cylinder; 64. groove; 7. transfer device; 71. electric slide; 72. mobile platform; 73. dust cover; 8. second reciprocating mechanism; 81. guide rail; 82. guide rail platform; 83. servo motor; 9. split control cabinet. DETAILED DESCRIPTION

[0031] The present application is described in detail below. Although specific embodiments of the present application are shown, it should be understood that the present application can be implemented in various forms and should not be limited by the embodiments described herein. On the contrary, these embodiments are provided to enable a more thorough understanding of the present application and to fully convey the scope of the present application to those skilled in the art.

[0032] It should be noted that certain words are used in the specification and claims to refer to specific components. Those skilled in the art should understand that technicians may use different nouns to refer to the same component. This specification and claims do not use the difference in nouns as a way to distinguish components, but use the functional differences of components as the criterion for distinction. As mentioned throughout the specification and claims, "including" or "comprising" are open-ended terms and should be interpreted as "including but not limited to". The subsequent description of the specification is a preferred embodiment of the present application, but the description is based on the general principles of the specification and is not intended to limit the scope of the present application. The scope of protection of the present application shall be determined by the attached claims.

[0033] refer to Figure 1 The present application provides a packaging device, which is used to package test tubes having a bottle cap 12 and a bottle body 11. The packaging device includes a base 1, a tube body control group 5 and a filling control group 2.

[0034] refer to Figure 2 The filling control group 2 is used to fill the inside of the test tube, and the filling control group 2 is fixed on the base 1; the filling control group 2 includes a capping device 3 and a filling device 4, the capping device 3 is used to screw on or off the bottle cap 12 of the test tube, and the filling device 4 is used to fill the test tube;

[0035] refer to Figure 3 and Figure 4 The tube body control group 5 is used to move the test tube, and the tube body control group 5 can transport the test tube to the position where the filling control group 2 performs filling; the tube body control group 5 includes a fixing device 6 and a transfer device 7, the fixing device 6 is used to fix the bottle body 11 of the test tube, and the transfer device 7 is used to move the test tube to the rotating bottle cap 12 or the filling position.

[0036] In this application, the x-axis direction, y-axis direction, and z-axis direction are as follows: Figure 1-4 The coordinates of the lower right corner are shown.

[0037] refer to Figure 2, use the filling equipment to fill the liquid into the test tube, wherein the filling control group 2 is used to fill the test tube, and for the test tube with the bottle cap 12, the filling control group 2 can also unscrew the bottle cap 12 from the bottle body 11, and then fill the bottle body 11, and then screw the unscrewed bottle cap 12 onto the filled bottle body 11, so as to complete the filling of the test tube.

[0038] refer to Figure 1 The tube body control group 5 is used to transfer the test tubes. The test tubes that need to be filled need to be placed on the test tube tray 51 first, and then the tube body control group 5 will drive the test tubes to move on the base 1. When the test tubes move along the x-axis on the base 1, they will be accurately moved to the rotating bottle cap 12 or the filling position of the filling control group 2. In this way, the filling control group 2 only needs to move up and down, and the movement of the test tubes can be completed by the tube body control group 5, reducing the workload of a single component of the filling control group 2 or the tube body control group 5 during the filling process, so that the workload gap between the filling control group 2 and the tube body control group 5 is reduced. On the one hand, since the workload of a single component is reduced accordingly, the relative service life of the tube body control group 5 and the filling control group 2 is improved. On the other hand, since the workload in the test tube filling process is evenly distributed to different components, the probability of failure of the filling control group 2 or the tube body control group 5 during the working process is further reduced, and the coordination between different components is improved, which can achieve the purpose of reducing equipment failure and improving work efficiency.

[0039] refer to Figure 2 In a specific embodiment, the filling control group 2 includes a gantry bracket 21 , the gantry bracket 21 is fixedly connected to the base 1 , and the capping device 3 and the filling device 4 are both arranged on the gantry bracket 21 .

[0040] The connection between the gantry support 21 and the base 1 is a fixed connection, and specifically, the fixed connection can be welding, bonding, bolt connection or riveting, etc. Those skilled in the art can choose according to actual conditions.

[0041] refer to Figure 2 , the gantry bracket 21 on the base 1 has a greater strength due to the fixed connection method. Therefore, the gantry bracket 21 can withstand a larger load. Furthermore, when the gantry bracket 21 is under load for a long time, the stable fixed connection structure can greatly reduce the deformation of the gantry during operation, thereby allowing the gantry bracket 21 to be used for a longer time while maintaining accuracy. In other words, by changing the layout of the components in the packaging equipment, the gantries are connected to the base 1 in a fixed manner, which greatly improves the service life of the gantries while also greatly improving the accuracy of the components on the gantry bracket 21.

[0042] refer to Figure 2 The capping device 3 and the filling device 4 are both arranged between the gantry, so that the capping device 3 can move more accurately between the gantry, which helps the capping device 3 to be accurately positioned on the bottle cap 12, and then the bottle cap 12 can be screwed off or screwed on. Similarly, the filling device 4 can be accurately positioned inside the bottle body 11 for filling.

[0043] refer to Figure 2 In a specific embodiment, the filling control group 2 includes an outer cover shell 22, the interior of the outer cover shell 22 is hollow, and the gantry bracket 21, the capping device 3 and the filling device 4 are all arranged inside the outer cover shell 22; the outer cover shell 22 is detachably connected to the base 1; and the outer cover shell 22 is provided with an opening for the test tube to enter the position of the capping device 3 and the filling device 4.

[0044] refer to Figure 2 The outer cover shell 22 is made of ABS material, which is non-toxic and harmless, and is safer to use. The outer cover shell 22 is wear-resistant and high-temperature-resistant, and can withstand the heat generated by the filling equipment during operation. The outer cover shell 22 also has the characteristics of high impact resistance; the outer cover shell 22 can protect the gantry bracket 21, the capping device 3 and the filling device 4 inside it; and reduce the damage caused by the external environment to the internal equipment of the outer cover shell 22 in unexpected situations.

[0045] The outer cover shell 22 not only has a protective function, but also has dustproof and isolation functions. The gantry, the capping device 3 and the filling device 4 are arranged in a hollow position inside the outer cover shell 22. Therefore, when the dust falls, it falls inside the outer cover shell 22, thereby reducing the dust from entering the capping device 3 and the filling device 4, which hinders the operation of the capping device 3 and the filling device 4, and at the same time can reduce the impact of dust on the accuracy of the capping device 3 and the filling device 4. Further, the outer cover shell 22 can also isolate the capping device 3 and the filling device 4 located inside it from the external environment; reduce the impact of debris or other substances in the external environment. Furthermore, the outer cover shell 22 can enable the capping device 3 and the filling device 4 to be used for a longer time while maintaining accuracy. The service life of the capping device 3 and the filling device 4 is increased.

[0046] refer to Figure 2In the present application, the gantry support 21 is fixed on the base 1, so when the test tube needs to unscrew or screw on the bottle cap 12, the test tube needs to be moved to the position of the gantry support 21 for processing, so the test tube needs to pass through the outer cover shell 22 from the opening and enter the position of the gantry support 21. The opening is set at a position close to the bottom of the outer cover shell 22, so the outer cover shell 22 can still perform dust prevention and isolation on the capping device 3 and the filling device 4.

[0047] In a specific embodiment, the capping device 3 includes an electric clamp 32 and a first reciprocating mechanism, wherein the electric clamp 32 can clamp and rotate the bottle cap 12; the first reciprocating mechanism can drive the electric clamp 32 to move back and forth; preferably, the first reciprocating mechanism can drive the electric clamp 32 to move back and forth in the z-axis direction.

[0048] refer to Figure 2 The electric clamp 32 has a head end capable of clamping, and the electric clamp 32 can clamp and fix the bottle cap 12 of the test tube. At the same time, the clamping head end of the electric clamp 32 can also rotate around its own central axis to unscrew the bottle cap 12 from the bottle body 11.

[0049] refer to Figure 3 The electric rotation can move under the action of the first reciprocating mechanism, thereby unscrewing the bottle cap 12 from the bottle body 11, and then the first reciprocating mechanism removes the electric clamp 32 and the unscrewed bottle cap 12 together, thereby allowing the filling device 4 to fill the bottle body 11 after the bottle cap 12 is unscrewed.

[0050] When the first reciprocating mechanism drives the electric clamp 32 to move, it can move along the z-axis direction or tilt along the angle between the z-axis direction and the x-axis direction, and both can move the bottle cap 12 away so that the filling device 4 can fill the bottle body 11. Specifically, when the first reciprocating structure 31 is installed on the gantry bracket 21, it can be installed at a certain angle with the z-axis direction, so that the first reciprocating mechanism can still drive the electric clamp 32 to move. Preferably, the first reciprocating mechanism drives the electric clamp 32 to move in the z-axis direction.

[0051] refer to Figure 3, and in the art, since the test tube needs to be filled, when the test tube is fixed, the test tube will be placed vertically along the z-axis to reduce the splashing or leakage of liquid during the test tube filling process. When the electric clamp 32 unscrews the bottle cap 12 from the bottle body 11, the bottle cap 12 will move upward under the action of the thread. Therefore, the electric clamp 32 is set in the z-axis direction. When the electric clamp 32 unscrews the bottle cap 12, the electric clamp 32 can adaptively slide upward as the bottle cap 12 is unscrewed under the action of the first reciprocating mechanism, so that the bottle cap 12 can be unscrewed from the bottle body 11. Furthermore, since the electric clamp 32 can rise as the bottle cap 12 is unscrewed, the force of the threaded connection between the bottle cap 12 and the bottle body 11 is greatly reduced or even eliminated, thereby reducing the interaction force between the bottle cap 12 and the bottle body 11 when the electric clamp 32 is unscrewed, thereby reducing or preventing the possibility of damage to the bottle cap 12 and the bottle body 11.

[0052] refer to Figure 3 In a specific embodiment, the electric clamp 32 is provided with a clamp adapted to the size of the bottle cap 12; two clamps are arranged opposite to each other, and the two clamps can move in a direction away from or close to each other, and the two clamps are provided with a knurled structure on two adjacent side surfaces; the clamp is detachably connected to the electric clamp 32.

[0053] The clamp is arranged at the head end of the electric clamp 32, and the clamp is used to clamp the bottle cap 12. At the same time, when the clamp is installed on the head end of the electric clamp 32, the head end of the electric clamp 32 can drive the clamp to rotate.

[0054] refer to Figure 3 The two clamps are both curved to match the bottle cap 12 on the side close to each other. When the two clamps are close to each other, the bottle cap 12 is clamped, and the electric clamp 32 drives the clamp to rotate to unscrew the bottle cap 12 from the bottle body 11.

[0055] When the test tube has different sizes or shapes, for example, the test tube is a square tube or a round tube, the clamp can be adaptively adjusted according to different models of the test tube.

[0056] refer to Figure 3In the art, in order to facilitate the rotation of the bottle cap 12, the test tube is provided with knurling on the outer peripheral surface of the bottle cap 12. Therefore, in the present application, a knurling structure that fits with the knurling of the test tube is provided on the sides of the two clamps that are close to each other. The knurling structure on the clamp can be adapted to the knurling on the bottle cap 12, thereby increasing the force between the clamp and the bottle cap 12, and facilitating the rotation force of the electric clamp 32 on the bottle cap 12. The possibility of idling when the clamp and the electric clamp 32 rotate the bottle cap 12 is reduced; thereby improving the efficiency of rotating the bottle cap 12.

[0057] In a specific embodiment, the tube body control group 5 includes a test tube tray 51, which is used to place the bottle body 11. The test tube tray 51 and the fixing device 6 are both fixed on a transfer device 7, and the transfer device 7 can move the test tube tray 51 and the fixing device 6 to the bottom of the electric clamp 32.

[0058] refer to Figure 4 The test tube tray 51 is plate-shaped, and a plurality of test tube slots are provided on the test tube tray 51; the test tube slots are arranged in a matrix; and the test tubes are placed in the test tube slots.

[0059] The gantry support 21 is fixed on the base 1, and the electric gripper 32 can only move in the z-axis direction. Therefore, when the electric gripper 32 is needed to clamp the test tube, the transfer device 7 will move the test tube tray 51 or the fixing device 6 to the bottom of the gantry support 21, and then the first reciprocating mechanism will move the electric gripper 32 to the top of the test tube, so that the electric gripper 32 can clamp the test tube or rotate the bottle cap 12. Then the bottle cap 12 of the test tube is unscrewed.

[0060] refer to Figure 4 When in use, the test tube is first placed on the test tube tray 51, and then the transfer device 7 moves the test tube tray 51 to the bottom of the gantry support 21, and then the first reciprocating mechanism moves the electric gripper 32 to the top of the test tube, and the electric gripper 32 clamps the test tube and takes it out of the test tube tray 51, the transfer device 7 removes the test tube tray 51, and moves the fixing device 6 to the bottom of the electric gripper 32, and then the first reciprocating mechanism moves the electric gripper 32 downward, and the test tube clamped by the electric gripper 32 is placed in the fixing device 6, the fixing gripper releases the test tube, the fixing device 6 fixes the test tube, and then the fixing gripper clamps the bottle cap 12 of the test tube, and unscrews the bottle cap 12 from the bottle body 11. The process of unscrewing the bottle cap 12 from the bottle body 11 is completed.

[0061] refer to Figure 4In the present application, the test tube can be transferred by moving the test tube tray 51 and the fixing device 6 using the transfer device 7, thereby making the electric gripper 32 move up and down on the gantry bracket 21. It is worth mentioning that in the present application, the transfer device 7 is used to control the movement of the test tube tray 51 and the fixing device 6, and the test tube tray 51 and the fixing device 6 are fixed on the moving part of the transfer device 7, and the movement of the test tube tray 51 and the fixing device 6 on the transfer device 7 is small, so the dynamic force on the moving part of the transfer device 7 is small, which reduces the wear of the transfer device 7 and improves the service life of the transfer device 7.

[0062] In a specific embodiment, the transfer device 7 includes an electric slide 71 arranged on the base 1, and the electric slide 71 is provided with a mobile platform 72 which is slidably connected to the base 1. The electric slide 71 can drive the mobile platform 72 to move back and forth, and the fixing device 6 and the fixed tray 61 are both arranged on the mobile platform 72; preferably, the electric slide 71 can drive the mobile platform 72 to move back and forth along the x-axis.

[0063] refer to Figure 4 The electric slide 71 is a conventional electric slide 71 in the art, the mobile platform 72 is plate-shaped, the mobile platform 72 is used to connect the test tube tray 51 and the fixing device 6, and the test tube tray 51 and the fixing device 6 are both connected to the electric slide 71 through the mobile platform 72.

[0064] refer to Figure 4 A dust cover 73 is also provided on the base 1. The dust cover 73 is a hollow structure. The electric slide 71 is located in a chamber formed between the dust cover 73 and the base 1. The dust cover 73 can protect and isolate the electric slide 71, and can also reduce the situation where dust enters the electric slide 71. Thus, the possibility of dust damaging the electric slide 71 is reduced.

[0065] refer to Figure 4 The mobile platform 72 is arranged above the outer side of the dust cover 73, and a clearance hole is opened on the dust cover 73. The mobile platform 72 and the electric slide 71 located on the inner and outer sides of the dust cover 73 are connected at the position of the clearance hole; the mobile platform 72 and the electric slide 71 pass through the dust cover 73 through the clearance hole. The clearance hole extends along the movement direction of the mobile platform 72. The electric slide 71 can drive the mobile platform 72 to reciprocate through the clearance hole.

[0066] Furthermore, the movable platform 72 covers the clearance hole, and the movable platform 72 can seal the clearance hole, reducing the possibility of dust or dirt entering the dust cover 73 from the clearance hole. The service life of the movable platform 72 is further improved. On the other hand, the test tube tray 51 and the fixing device 6 are connected to the electric slide 71 at the same time through the movable platform 72, so that the test tube tray 51 and the fixing device 6 can be moved by the electric slide 71 at the same time, reducing the mechanism for driving the test tube tray 51 and the fixing device 6, and simplifying the structure of the packaging equipment.

[0067] In a specific embodiment, the fixing device 6 includes a fixed tray 61 and a fixed push plate 62. The fixed tray 61 is provided with a plurality of grooves 64 for placing the bottle body 11. The fixed push plate 62 can push each bottle body 11 located in the groove 64 and fix the bottle body 11. The fixed push plate 62 is connected to an electric cylinder 63, and the electric cylinder 63 can drive the fixed push plate 62 to move back and forth; preferably, the electric cylinder 63 can drive the fixed push plate 62 to move along the x-axis direction.

[0068] refer to Figure 4 The fixed tray 61 is in a rectangular shape, and the length of the fixed tray 61 in the x-axis direction is adapted to the test tube tray 51 , so that the test tubes on the fixed tray 61 can be clamped onto the fixed tray 61 by the electric clamp 32 .

[0069] refer to Figure 4 The inner diameter of the groove 64 is larger than the outer diameter of the bottle body 11 of the test tube. The test tube is clamped by the electric clamp 32; then the transfer device 7 moves the fixed tray 61 to the bottom of the electric clamp 32, and then puts the test tube into the groove 64 on the fixed tray 61, and then places the test tube on the fixed tray 61.

[0070] refer to Figure 4 The fixed push plate 62 is used to push up the test tube placed on the fixed tray 61, thereby fixing the test tube on the fixed tray 61.

[0071] The fixed tray 61 has a hole on the side flush with the groove 64, the hole is connected to the groove 64, and the fixed push plate 62 can push the side of the test tube in the groove 64 through the hole to fix the test tube.

[0072] refer to Figure 4The fixed push plate 62 is provided with a top block corresponding to the hole, and the top block can enter the hole and abut against the test tube in the groove 64. There are multiple top blocks, and the top blocks correspond to the holes one by one. The top block is made of soft material at one end close to the fixed tray 61, which reduces the possibility of damaging the test tube when pushing the test tube.

[0073] refer to Figure 4 When the test tube is placed in the groove 64 of the fixed tray 61, the fixed push plate 62 pushes the top block into the hole, and the top block abuts against the test tube, and then the top block abuts the test tube tightly against the inner wall of the groove 64. The test tube is fixed in the groove 64.

[0074] refer to Figure 4 The electric cylinder 63 can drive the fixed push plate 62 and the top block to move back and forth, thereby fixing and releasing the test tube in the groove 64.

[0075] refer to Figure 4 , a fixed push plate 62 and a fixed tray 61 are used to fix the bottle body 11 of the test tube, and the size of the groove 64 on the fixed tray 61 is larger than the size of the test tube, which enables the fixed tray 61 and the fixed push plate 62 to fix test tubes of more sizes; the adaptability of the fixing device 6 is improved. In addition, due to the limitation of the number of filling devices 4 and electric clamps 32, only a limited number of test tubes can be operated when rotating and capping the test tubes. Therefore, in the present application, a fixed tray 61 and a fixed push plate 62 are separately set up to fix the test tubes, so that the number of the fixing device 6 is adapted to the capping and filling processes, reducing the manufacturing cost of the packaging equipment and further simplifying the structure of the packaging equipment.

[0076] refer to Figure 2 and Figure 3 In a specific embodiment, a second reciprocating mechanism 8 is arranged on the gantry bracket 21, and the second reciprocating mechanism 8 is respectively connected to the filling device 4 and the capping device 3, and the second reciprocating mechanism 8 can drive the filling device 4 and the capping device 3 to reciprocate. Preferably, the second reciprocating mechanism 8 can drive the filling device 4 and the capping device 3 to reciprocate along the y-axis.

[0077] There are multiple electric clamps 32 , and the specific numbers of the electric clamps 32 are: 1, 2, 3, 4, 5, 6, 7, 8, 9, and 10.

[0078] The electric clamps 32 are arranged in parallel along the y-axis direction.

[0079] The longer side of the fixed tray 61 is arranged along the y-axis direction, and there are multiple grooves 64 opened on the fixed tray 61, and the multiple grooves 64 are evenly opened on the fixed tray 61 along the y-axis direction; the specific number of the grooves 64 is: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10.

[0080] In a specific embodiment, the number of the grooves 64 is equal to the number of the electric clamps 32 .

[0081] In another specific embodiment, the number of the grooves 64 is twice the number of the electric clamps 32 .

[0082] refer to Figure 1 The test tube tray 51 has a plurality of test tube slots, which are arranged in a matrix on the test tube tray 51, wherein the number of the test tube slots in the y-axis direction is equal to the number of the grooves 64 on the fixed tray 61. The number of the test tube slots in the x-axis direction can be determined according to actual conditions and the size of the test tube tray 51.

[0083] refer to Figure 1 The transfer device 7 drives the test tube tray 51 and the fixing device 6 to move in the x-axis direction, so the test tube can be moved in the x-axis direction under the joint action of the electric clamp 32 and the transfer device 7.

[0084] However, due to the large size of the electric gripper 32 or the filling device 4, the rotation space required for the bottle cap 12 to rotate, and the sufficient space required for the electric gripper 32 to operate when transferring or clamping the test tube, the test tubes to be fixed need to have a certain distance between them, which limits the number of test tubes that can be clamped by the electric gripper 32 when clamping the test tubes. That is, when the electric gripper 32 clamps the test tubes, in the y-axis direction, the electric gripper 32 can only clamp the test tubes with a certain distance.

[0085] Therefore, in the present application, the second reciprocating mechanism 8 can drive the electric clamp 32 and the filling device 4 to move along the y-axis direction, thereby enabling the electric clamp 32 and the filling device 4 to move to the interval position between the test tubes. The electric clamp 32 can clamp more test tubes placed on the test tube tray 51, and the electric clamp 32 and the filling device 4 can move in the y-axis direction, thereby increasing the filling equipment to fill more test tubes in a limited space, simplifying the structure of the filling equipment, and increasing the working efficiency of the filling equipment.

[0086] refer to Figure 2 and Figure 3In a specific embodiment, the second reciprocating mechanism 8 includes a guide rail 81 fixed on the gantry bracket 21 and a guide rail platform 82 slidably connected to the guide rail 81, the capping device 3 and the filling device 4 are both fixed to the guide rail platform 82, and a servo motor 83 is provided on the gantry bracket 21, and the output shaft of the servo motor 83 is threadedly connected to the guide rail platform 82 using a screw.

[0087] The guide rail 81 is arranged along the y-axis direction, and the guide rail platform 82 is fixedly connected to the capping device 3 and the filling device 4, so the guide rail platform 82 can simultaneously drive the capping device 3 and the filling device 4 to move in the y-axis direction, thereby simplifying the structure of the subpackaging equipment.

[0088] refer to Figure 3 A connecting seat is fixedly connected to the lower surface of the top of the gantry bracket 21, and the slide rail is fixedly connected to the lower surface of the connecting seat. The slide rail platform is arranged below the connecting seat and is slidably connected to the slide rail. On the one hand, the slide rail can be used to guide the slide rail platform; on the other hand, the slide rail also supports the slide rail platform, and the slide rail hoists the slide rail platform on the gantry bracket 21.

[0089] refer to Figure 3 The frame of the servo motor 83 is mounted on the connecting seat, and the output shaft of the servo motor 83 is threadedly connected to the slide rail platform. Therefore, when the servo motor 83 rotates, it will drive the slide rail platform to slide along the slide rail under the action of the threaded connection.

[0090] The servo motor 83 drives the slide platform to slide by means of a threaded connection. On the one hand, the threaded connection has a large speed reduction ratio. Therefore, when the servo motor 83 rotates, the slide platform can move at a slow sliding speed, which greatly improves the sliding accuracy of the slide platform. Then, the capping device 3 and the filling device 4 connected to the slide platform can more accurately cap and fill the test tube. On the other hand, the threaded connection has a self-locking function. When the servo motor 83 stops rotating, the slide platform will stop at the stop position. Even if the slide platform is subjected to a force, due to the self-locking property of the threaded connection, the slide platform can still be fixed at the target position. The accuracy of the slide platform is further improved.

[0091] refer to Figure 3 In a specific embodiment, the filling device 4 includes a third reciprocating mechanism 41, an injection head 42 and a peristaltic pump 43, one end of the peristaltic pump 43 is connected to the injection head 42, and the injection head 42 is arranged on the third reciprocating mechanism 41. The third reciprocating mechanism 41 can drive the injection head 42 to move back and forth to achieve filling into the test tube; preferably, the third reciprocating mechanism 41 can drive the injection head 42 to move back and forth along the z-axis direction.

[0092] refer to Figure 3 The filling device 4 is used to fill the medicine into the bottle body 11. One end of the peristaltic pump 43 is placed in the medicine solution to be filled, and the other end of the peristaltic pump 43 is used to fill the bottle body 11.

[0093] refer to Figure 2 In the present application, a peristaltic pump 43 is used for pumping, and the peristaltic pump 43 has good sealing performance. When the peristaltic pump 43 transports liquid, the medium that is displaced and in contact with the peristaltic pump 43 is only the hose inside the peristaltic pump 43, which reduces the connection of valves or other components and reduces the possibility of liquid leakage when the peristaltic pump 43 is used to pump the liquid. In addition, the good sealing performance greatly reduces the possibility of the solution being contaminated or adulterated with impurities during the pumping process.

[0094] refer to Figure 3 The injection head 42 is in the shape of a needle tube and is made of metal. When the injection head 42 injects liquid into the bottle body 11, the lower end of the injection head 42 can enter the bottle body 11 and inject liquid from the bottom of the bottle body 11, which reduces the splashing of liquid when it is injected into the bottle body 11, thereby reducing the waste of liquid and the pollution of the solution to the environment. In addition, using the injection head 42 to inject from the bottom of the bottle body 11 can greatly reduce the bubbles generated in the liquid due to the splashing of the liquid when the solution is injected. This improves the accuracy of solution injection and increases the quality of the liquid injected into the bottle body 11.

[0095] The packaging equipment further comprises a split control cabinet (not shown in the figure), which is capable of controlling the operation of the tube body control group 5 and the filling control group 2 .

[0096] The split control cabinet can be connected to the tube control group 5 and the filling control group 2 by wired connection or wireless connection.

[0097] By using a split control cabinet, the operation of the tube control group 5 and the filling control group 2 can be controlled at a location far away from the base 1 .

[0098] In a specific embodiment, the base 1, the tube control group 5 and the filling control group 2 are all located in a closed space. In this case, the staff can place the split control cabinet outside the sealed space, and control the tube control group 5 and the filling control group 2 in the closed space by controlling the split control cabinet, thereby completing the subpackaging of the test tubes. The applicability of the subpackaging equipment is improved.

[0099] Example

[0100] The present application provides a packaging device, wherein the bottle cap 12 of the test tube is threadedly connected to the bottle body 11. The base 1 is made of aluminum alloy, and the base 1 is made of 7075 aluminum alloy. Four adjustment feet are respectively arranged at the four corners below the base 1, and the four adjustment feet are threadedly connected to the base 1. The base 1 is placed in a horizontal plane by rotating the adjustment feet, and the adjustment feet are all made of 304 stainless steel.

[0101] The electric slide 71 is arranged on the base 1, and the electric slide 71 is a TOYO slide, and the model of the electric slide 71 is GT8-L5-500-BR-M20-C3. Above the electric slide 71 is a dust cover 73, and the dust cover 73 is made of 304 stainless steel. Above the dust cover 73 is a mobile platform 72, and the mobile platform 72 is connected to the electric slide 71, and the mobile platform 72 is made of 7075 aluminum alloy. The electric slide 71 can drive the mobile platform 72 to move back and forth along the x-axis.

[0102] A test tube tray 51 is arranged on the electric platform. The test tube tray 51 is made of nylon plate, and a tube hole matching the diameter of the bottle body 11 is opened on the test tube tray 51. The fixed tray 61 is made of nylon, the main frame structure of the fixed push plate 62 is made of aluminum alloy, and the material at the position in contact with the test tube is polyurethane. The fixed tray 61 and the fixed push plate 62 are both fixed on the mobile platform 72. The model of the electric cylinder 63 is Dahuan MCE-3G-04-050-C-0-B-L5-0. One electric cylinder 63 is arranged at each end of the fixed push plate 62.

[0103] The lower ends of the gantry brackets 21 are respectively fixed on the base 1 . The gantry brackets 21 are made of 7075 aluminum alloy material and have the advantages of strong corrosion resistance, high strength, and light weight.

[0104] A second reciprocating mechanism 8 is fixedly connected to the lower inner side of the gantry bracket 21, and the frame of the second reciprocating mechanism 8 is fixedly connected to the gantry bracket 21. The servo motor 83 is also fixedly connected to the gantry bracket 21. The guide rail 81 is fixedly connected to the lower part of the frame. The guide rail platform 82 is slidably connected to the guide rail 81, and the guide rail platform 82 and the output shaft of the servo motor 83 are threadedly connected using a screw rod. When the servo motor 83 rotates, it can drive the guide rail platform 82 to slide back and forth along the guide rail 81. The model of the servo motor 83 is SIEMENS 1FL60242AF211AB1. The model of the screw rod is BKBF10 1204*200. The guide rail 81 is made of bearing steel; the guide rail platform 82 is made of aluminum alloy.

[0105] The filling device 4 and the capping device 3 are both arranged below the guide rail platform 82. The first reciprocating structure 31 and the second reciprocating mechanism 8 are both fixedly connected below the guide rail platform 82. The first reciprocating mechanism and the third reciprocating mechanism 41 are both slide mechanisms. The models of the first reciprocating mechanism and the third reciprocating mechanism 41 are both TOYO GTH5-L5-100-BL-T10-C4.

[0106] The electric clamp 32 is fixedly connected to the first reciprocating mechanism, and the first reciprocating structure 31 can drive the electric clamp 32 to reciprocate along the z-axis. The model of the electric clamp 32 is Welling Motor Z-Mod-MS-80-50. A total of 6 electric clamps 32 are arranged along the y-axis direction. The clamps of the electric clamp 32 include multiple models that can adapt to test tubes of different specifications, and the clamps of the electric clamp 32 are custom-made from 304 stainless steel. The peristaltic pump 43 is fixedly connected to the side of the gantry bracket 21. The model of the peristaltic pump 43 is ALITEA wd-114-uk-03. The peristaltic pump 43 is connected to the injection head 42 using a silicone hose. The injection head 42 is connected to the third reciprocating structure, and the third reciprocating structure can drive the injection head 42 to reciprocate along the z-axis direction, and then place the injection head 42 inside the bottle body 11 for filling. The injection head 42 is made of stainless steel 316L.

[0107] The outer shell is arranged on the outside of the gantry support 21, and the gantry support 21, the filling device 4, and the capping device 3 are all covered inside the outer shell 22. The outer shell 22 can protect them and reduce the possibility that the filling device 4 is affected by the outside when filling the test tube. The outer shell 22 is made of ABS material, and has the advantages of high impact strength, wear resistance and high temperature resistance, and the outer shell 22 is non-toxic and harmless.

[0108] The filling equipment also includes a split control cabinet, which is used to control the movement between various components during the test tube filling process. The split control cabinet mainly controls all functions of the equipment through HMI operation.

[0109] In summary, the present application provides a packaging device for packaging test tubes. When the packaging device is used, multiple test tubes are first placed in the test tube slots of the test tube tray 51, and the pump end of the peristaltic pump 43 is placed in the liquid to be packaged. Then, the packaging device is turned on and the operation of the packaging device is controlled by the split control cabinet.

[0110] The transfer device 7 controls the test tube tray 51 to move to the bottom of the gantry support 21, and then the electric clamp 32 moves downward under the action of the first reciprocating mechanism, and then the clamp of the electric clamp 32 clamps the upper end of the test tube, and the first reciprocating mechanism moves upward. The electric clamp 32 takes the test tube out of the test tube tray 51. The transfer device 7 continues to move, moves the fixed tray 61 to the bottom of the gantry support 21, and aligns the groove 64 of the fixed tray 61 with the test tube clamped by the electric clamp 32. The electric clamp 32 moves downward, releases the clamping of the test tube, and places the test tube in the groove 64 of the fixed tray 61, and the electric clamp 32 moves upward slightly. Then the electric cylinder 63 drives the fixed push plate 62 to push the test tube and fix the test tube in the groove 64. The transfer device 7 moves according to the actual situation to align the test tube in the groove 64 with the electric clamp 32. Then the electric gripper 32 moves down to clamp the bottle cap 12 of the test tube, the clamp of the electric gripper 32 rotates, and the electric gripper 32 moves up to unscrew the bottle cap 12. After unscrewing the bottle cap 12, the transfer device 7 continues to move to move the bottle body 11 to the bottom of the injection head 42, and the third reciprocating mechanism 41 moves down to allow the injection head 42 to enter the inside of the bottle body 11. The peristaltic pump 43 is started to pump the liquid into the bottle body 11. After the liquid in the bottle body 11 is pumped to the required volume, the third reciprocating mechanism 41 moves up to remove the injection head 42 from the bottle body 11. The transfer device 7 transfers the filled bottle body 11 to the bottom of the electric gripper 32 and aligns it with the bottle cap 12 clamped by the electric gripper 32. Then the first reciprocating mechanism drives the electric clamp 32 to move down, so that the bottle cap 12 is aligned with the bottle body 11, and then the electric clamp 32 drives the fixture to rotate, and at the same time the first reciprocating mechanism adaptively moves down to screw the bottle cap 12 on. In order to prevent the test tube from being damaged when the fixation is released, the electric clamp 32 is first controlled to loosen the bottle cap 12, and then the electric cylinder 63 is controlled to move the fixed push plate 62. The transfer device 7 adaptively transfers the filled test tube to the bottom of the electric clamp 32 according to the actual situation. Then the electric clamp 32 moves down to clamp the test tube on the fixed tray 61, and then the transfer device 7 operates to move the test tube tray 51 to the bottom of the electric clamp 32, and the electric clamp 32 moves down to put the test tube back on the test tube tray 51. In this way, the subpackaging of the test tube is completed.

[0111] After the test tubes are packaged once, the second reciprocating mechanism 8 is controlled to operate so that the electric gripper 32 and the filling device 4 move along the y-axis direction, while keeping the electric gripper 32 able to clamp the test tubes on the test tube tray 51. Then the test tubes are packaged according to the above steps. After the test tubes on the test tube tray 51 are packaged once, the second reciprocating mechanism 8 shown will operate to swap the electric gripper 32 and the filling device 4 so that the electric gripper 32 can clamp the test tubes located between the test tubes packaged for the first time; and after the test tubes are taken out, the second reciprocating mechanism 8 operates according to the actual situation so that the test tubes can be placed in the grooves of the fixed tray 61. In another specific embodiment, after the test tubes are packaged in the x-axis direction on the test tube tray 51, the second reciprocating mechanism 8 can be operated to control the electric gripper 32 and the filling device 4 to swap positions. The staff can control it according to the actual situation.

[0112] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make modifications to the present embodiment without any creative contribution as needed, but such modifications are protected by the patent law as long as they are within the scope of the claims of the present application.

Claims

1. A packaging device, wherein: It is used to pack test tubes with bottle caps and bottle bodies, and the packing equipment includes: Base, tube control group and filling control group; The filling control group is used to fill the inside of the test tube, and the filling control group is fixed on the base; the filling control group includes a capping device and a filling device, the capping device is used to screw on or off the bottle cap of the test tube, and the filling device is used to fill the test tube; The tube body control group is used to move the test tube, and the tube body control group can transport the test tube to the position where the filling control group performs filling; the tube body control group includes a fixing device and a transfer device, the fixing device is used to fix the bottle body of the test tube, and the transfer device is used to move the test tube to the position of rotating the bottle cap or filling.

2. According to the packaging equipment according to claim 1, the filling control group includes a gantry bracket, the gantry bracket is fixedly connected to the base, and the capping device and the filling device are both arranged on the gantry bracket.

3. According to the packaging equipment according to claim 2, the filling control group includes an outer cover shell, the interior of the outer cover shell is hollow, and the gantry bracket, the capping device and the filling device are all arranged inside the outer cover shell; the outer cover shell is detachably connected to the base; and an opening is provided on the outer cover shell for the test tube to enter the capping device and the filling device.

4. According to the packaging equipment described in any one of claims 1-3, the capping device comprises an electric clamp and a first reciprocating mechanism, the electric clamp can clamp and rotate the bottle cap; the first reciprocating mechanism can drive the electric clamp to move back and forth; preferably, the first reciprocating mechanism can drive the electric clamp to move back and forth in the z-axis direction.

5. According to the packaging equipment according to claim 4, the electric clamp is provided with a clamp adapted to the size of the bottle cap; two clamps are arranged opposite to each other, the two clamps can move in the direction away from or close to each other, and the two clamps are provided with a knurled structure on two adjacent side surfaces; the clamp is detachably connected to the electric clamp.

6. According to the packaging equipment according to claim 4, the tube body control group includes a test tube tray, the test tube tray is used to place the bottle body, the test tube tray and the fixing device are both fixed on a transfer device, and the transfer device can move the test tube tray and the fixing device to the bottom of the electric clamp.

7. According to the packaging equipment described in any one of claims 1-6, the fixing device includes a fixed tray and a fixed push plate, the fixed tray is provided with a plurality of grooves for placing the bottle bodies, the fixed push plate can push up each bottle body located in the groove and fix the bottle body, the fixed push plate is connected to an electric cylinder, and the electric cylinder can drive the fixed push plate to move back and forth; preferably, the electric cylinder can drive the fixed push plate to move along the x-axis direction.

8. According to the packaging equipment described in any one of claims 1-7, the transfer device includes an electric slide arranged on a base, the electric slide is provided with a mobile platform slidably connected to the base, the electric slide can drive the mobile platform to move back and forth, and the fixing device and the fixed tray are both arranged on the mobile platform; preferably, the electric slide can drive the mobile platform to move back and forth along the x-axis.

9. According to the packaging equipment according to claim 2, a second reciprocating mechanism is arranged on the gantry bracket, and the second reciprocating mechanism is respectively connected to the filling device and the capping device, and the second reciprocating mechanism can drive the filling device and the capping device to move reciprocatingly. Preferably, the second reciprocating mechanism can drive the filling device and the capping device to move reciprocatingly along the y-axis.

10. The packaging equipment according to claim 2, wherein the second reciprocating mechanism comprises a guide rail fixed on a gantry bracket and a guide rail platform slidably connected to the guide rail, the capping device and the filling device are both fixed to the guide rail platform, a servo motor is arranged on the gantry bracket, and the output shaft of the servo motor is threadedly connected to the guide rail platform using a screw.

11. According to any one of claims 1-10, the filling device comprises a third reciprocating mechanism, an injection head and a peristaltic pump, one end of the peristaltic pump is connected to the injection head, the injection head is arranged on the third reciprocating mechanism, and the third reciprocating mechanism can drive the injection head to move back and forth to realize filling into the test tube; preferably, the third reciprocating mechanism can drive the injection head to move back and forth along the z-axis direction.

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