Veterinary concentrated iodine mixed solution and preparation method thereof

Abstract

The invention discloses a concentrated iodine mixed solution for veterinary use and a preparation method thereof, the mixed solution comprises the following components in 100 parts by weight: 2-5 parts by weight of iodine, 2-5 parts by weight of potassium iodide, 15-25 parts by weight of a traditional Chinese medicine mixture extract, 1-5 parts by weight of quaternary ammonium salt, and the balance of plant essential oil, the traditional Chinese medicine mixture consists of honeysuckle, garlic, houttuynia cordata, purslane, coptis chinensis and radix sophorae flavescentis in a mass ratio of (2-5): (3-10): (1-5): (2-4): (5-8): (3-5). According to the invention, the potassium iodide, the quaternary ammonium salt, the traditional Chinese medicine mixture and the plant essential oil are used as raw materials, and the proportions of the components are controlled, so that the components have a synergistic effect, the sterilization efficiency is improved, the sterilization spectrum is expanded, and the prepared product has a killing effect on viruses, bacteria, fungi, mycoplasmas and spores.

Description

Technical Field

[0001] The invention relates to a concentrated iodine mixed solution for animals and a preparation method thereof, belonging to the technical field of animal disinfectants. Background Art

[0002] In the field of veterinary disinfection, with the development of modern intensive breeding industry, the closed and highly intensive breeding conditions have made livestock and poultry increasingly threatened by pathogenic microorganisms. In order to prevent the spread of pathogens, disinfection methods are usually used to kill pathogenic microorganisms. Currently, the commonly used disinfectants are mainly compound phenols, peroxides, aldehydes, chlorine-containing disinfectants, iodine, quaternary ammonium salts and other disinfectants.

[0003] Phenols, this type of disinfectant can denature and precipitate the proteins of pathogenic microorganisms to kill bacteria and kill common bacteria. Compound phenols can kill spores, viruses and fungi. They mainly include phenol, compound phenol, coal phenol, etc. However, aldehydes are carcinogenic, teratogenic, reduce the resistance of humans and animals, and have high costs.

[0004] Aldehydes also have strong bactericidal effects, among which formaldehyde has the best effect and is the most commonly used. With the advancement of production technology and the needs of the aquaculture industry, high-efficiency disinfectants such as glutaraldehyde and glyoxal are also widely used. However, phenols are highly irritating and toxic.

[0005] Iodine disinfectants are also widely used in medical clinics, sanitation, daily life, agriculture and animal husbandry, etc. because of their broad antibacterial spectrum, short killing time for microorganisms, and good safety. However, ordinary iodine preparations are highly irritating to the skin and mucous membranes, have deep coloring, poor stability, and are easily oxidized to lose their bactericidal effects. Therefore, the most commercially available and clinically used is complex iodine. Povidone iodine, also known as polyvinyl pyrrolidone (PVP-I), is a water-soluble polymer compound that slowly releases iodine and is formed by the combination of molecular iodine and PVP. This product has good water-soluble stability and can work for a long time, but polyvinyl pyrrolidone is a macromolecular substance that is not easily degraded in the natural environment. If it is used for long-term environmental spray disinfection or large-scale use on animal surfaces, it will inevitably threaten the health of humans and animals. In addition, the dosage of povidone iodine is large and the cost of use is high, so it is by no means the best choice for breeders.

[0006] In view of the above problems, this application is specially filed. Summary of the invention

[0007] In view of the shortcomings of the prior art, the first purpose of the present invention is to provide a concentrated iodine mixed solution for veterinary use.

[0008] The second object of the present invention is to provide a preparation method comprising the above-mentioned mixed solution.

[0009] In order to achieve the first purpose, the present invention is implemented through the following technical scheme: a concentrated iodine mixture for veterinary use, which comprises 2-5 weight parts of iodine, 2-5 weight parts of potassium iodide, 15-25 weight parts of Chinese medicine mixture extract, 1-5 weight parts of quaternary ammonium salt, and the remainder of plant essential oil based on 100 weight parts.

[0010] By adopting the above technical scheme, iodine is a highly effective disinfectant, which has a strong killing effect on bacterial propagules, fungi, mycobacteria and viruses. The raw material price of iodine is relatively high, and the bactericidal effect is single. The combination of iodine and other disinfectants has become a trend, and the effect is better than that of iodine alone.

[0011] Quaternary ammonium salts are a type of disinfectant widely used in livestock, poultry and aquaculture. Quaternary ammonium salts belong to cationic surfactants. The bactericidal mechanism of single-chain quaternary ammonium salts is adsorbed to the surface of bacteria, the hydrophobic base is inserted into the human lipid layer, the permeability of the cell wall and membrane is changed, the intracellular substances leak, the enzyme or protein is denatured, and finally the bacteria die.

[0012] The invention adopts potassium iodide, quaternary ammonium salt, Chinese medicine mixture and plant essential oil as raw materials, and controls the ratio of each component to produce synergistic effect between the components, thereby improving the sterilization efficiency and expanding the sterilization spectrum, so that the product prepared by the invention has a killing effect on viruses, bacteria, fungi, mycoplasma and spores.

[0013] Preferably, the Chinese medicine mixture consists of honeysuckle, garlic, houttuynia cordata, purslane, coptis root and sophora flavescens.

[0014] Preferably, the mass ratio of honeysuckle, garlic, houttuynia cordata, purslane, coptis root and sophora flavescens is 2-5:3-10:1-5:2-4:5-8:3-5.

[0015] By adopting the above technical solution, the addition amount of iodine and potassium iodide is reduced by adding the Chinese medicine mixture extract, and the Chinese medicine mixture extract is highly safe and pollution-free. At the same time, the sterilization efficiency is further improved and the sterilization spectrum is expanded by combining Chinese and Western medicine.

[0016] Preferably, the preparation method of the Chinese medicine mixture extract is specifically as follows: weigh the Chinese medicine mixture according to the ratio, soak it in distilled water for 5-8 hours, boil it until boiling, simmer it over low heat for 5-10 hours, cool it, filter it, concentrate it to 1 / 3 of the volume, and vacuum freeze-dry it to obtain the Chinese medicine mixture extract.

[0017] Preferably, the mass volume ratio of the traditional Chinese medicine mixture to distilled water is 1:5-10.

[0018] Preferably, the plant essential oil consists of tea tree essential oil, sandalwood essential oil, cinnamon essential oil and lavender essential oil.

[0019] Preferably, the mass ratio of the tea tree essential oil, sandalwood essential oil, cinnamon essential oil and lavender essential oil is 3-6:5-8:5-10:1-2.

[0020] With the above technical solution, tea tree essential oil has attracted much attention for its excellent anti-inflammatory and bactericidal effects. Tea tree essential oil has two main characteristics. One is that it can resist three types of microbial infections such as bacteria, fungi and viruses. The other is that it is a strong immune system stimulant that can improve the body's resistance. Tea tree essential oil has the advantages of analgesia, antibacterial, antifungal, anti-infection, anti-inflammatory, antioxidant, anti-parasitic, strong disinfection, antiviral, decongestant, digestion, expectorant, immune system stimulation, insecticide, nerve tonic, stimulant and tissue regeneration. Its disinfection ability is twelve times that of phenol and has a strong immune stimulation ability.

[0021] By combining tea tree essential oil, sandalwood essential oil, cinnamon essential oil and lavender essential oil, the bactericidal ability can be superimposed, greatly prolonging the bactericidal effect time.

[0022] Preferably, the pH of the concentrated iodine mixture is 4-5.

[0023] Preferably, the quaternary ammonium salt is one or more of benzalkonium bromide, dioctadecyldimethylammonium chloride, dioctadecyldimethylammonium chloride, hexadecyldimethylbenzyl ammonium chloride, dihexadecyldimethylammonium bromide, and N-dialkyldimethylbenzyl.

[0024] In order to achieve the second purpose, the present invention is implemented by the following technical scheme: a method for preparing a concentrated iodine mixed solution for animals, comprising the following steps:

[0025] S1: adding iodine, potassium iodide and quaternary ammonium salt to the plant essential oil, mixing and stirring at 400-600 r / min for 10-15 min to obtain a mixture A;

[0026] S2: Add the Chinese herbal medicine mixture extract to the mixture A, mix and stir at 100-200 r / min for 20-30 min to obtain a mixture B;

[0027] S3: Adjust the pH of the mixture B to 4-5 to obtain a concentrated iodine mixture for veterinary use.

[0028] Beneficial effects of the present invention:

[0029] (1) The present invention uses potassium iodide, quaternary ammonium salt, Chinese medicine mixture and plant essential oil as raw materials, and controls the ratio of each component to produce a synergistic effect between the components, thereby improving the bactericidal efficiency and expanding the bactericidal spectrum, so that the product prepared by the present invention has a killing effect on viruses, bacteria, fungi, mycoplasmas and spores.

[0030] (2) The present invention has certain volatility and strong penetrability, and can penetrate the cell wall more easily than using aldehydes or quaternary ammonium salts alone, and can enter bacterial cells and kill the cell nucleus, thereby quickly killing bacteria and other pathogens. DETAILED DESCRIPTION

[0031] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below in conjunction with specific implementation methods.

[0032] Example 1

[0033] A concentrated iodine mixed solution for animals comprises 2kg of iodine, 4kg of potassium iodide, 20kg of a traditional Chinese medicine mixture extract, 1kg of a quaternary ammonium salt, and 73kg of a plant essential oil.

[0034] In this embodiment, the Chinese medicine mixture consists of honeysuckle, garlic, houttuynia cordata, purslane, coptis root and sophora flavescens, and the mass ratio thereof is 2:5:3:2:8:4.

[0035] In this embodiment, the preparation method of the Chinese medicine mixture extract is specifically as follows: weigh the Chinese medicine mixture according to the ratio, soak it in distilled water for 8 hours, boil it until boiling, simmer it for 8 hours, cool it, filter it, concentrate it to 1 / 3 of the volume, and vacuum freeze-dry it to obtain the Chinese medicine mixture extract.

[0036] In this embodiment, the mass volume ratio of the Chinese medicine mixture to distilled water is 1:5.

[0037] In this embodiment, the plant essential oil is composed of tea tree essential oil, sandalwood essential oil, cinnamon essential oil and lavender essential oil, and the mass ratio thereof is 3:7:5:1.

[0038] In this embodiment, the pH of the concentrated iodine mixed solution is 4.

[0039] In the present embodiment, the quaternary ammonium salt is benzalkonium bromide.

[0040] A method for preparing a concentrated iodine mixed solution for animals comprises the following steps:

[0041] S1: adding iodine, potassium iodide and quaternary ammonium salt to the plant essential oil, mixing and stirring at 400 r / min for 15 min to obtain a mixture A;

[0042] S2: Add the Chinese herbal medicine mixture extract to mixture A, mix and stir at 200 r / min for 20 min to obtain mixture B;

[0043] S3: Adjust the pH of the mixture B to 4 to obtain a concentrated iodine mixture for veterinary use.

[0044] Example 2

[0045] A concentrated iodine mixed solution for animals comprises 3kg of iodine, 5kg of potassium iodide, 15kg of a traditional Chinese medicine mixture extract, 2kg of a quaternary ammonium salt, and 75kg of a plant essential oil.

[0046] In this embodiment, the Chinese medicine mixture consists of honeysuckle, garlic, houttuynia cordata, purslane, coptis root and sophora flavescens, and the mass ratio thereof is 5:3:1:3:5:3.

[0047] In this embodiment, the preparation method of the Chinese medicine mixture extract is specifically as follows: weigh the Chinese medicine mixture according to the ratio, soak it in distilled water for 5 hours, boil it until boiling, simmer it for 5 hours, cool it, filter it, concentrate it to 1 / 3 of the volume, and vacuum freeze-dry it to obtain the Chinese medicine mixture extract.

[0048] In this embodiment, the mass volume ratio of the Chinese medicine mixture to distilled water is 1:7.

[0049] In this embodiment, the plant essential oil consists of tea tree essential oil, sandalwood essential oil, cinnamon essential oil and lavender essential oil, and the mass ratio thereof is 5:5:10:1.

[0050] In this embodiment, the quaternary ammonium salt is hexadecyl dimethyl benzyl ammonium chloride.

[0051] The rest is the same as in Example 1.

[0052] Example 3

[0053] A concentrated iodine mixed solution for animals comprises 4kg of iodine, 2kg of potassium iodide, 22kg of a traditional Chinese medicine mixture extract, 3kg of a quaternary ammonium salt, and 69kg of a plant essential oil.

[0054] In this embodiment, the Chinese medicine mixture consists of honeysuckle, garlic, houttuynia cordata, purslane, coptis root and sophora flavescens, and the mass ratio thereof is 3:10:5:4:6:5.

[0055] In this embodiment, the mass volume ratio of the Chinese medicine mixture to distilled water is 1:10.

[0056] In this embodiment, the plant essential oil is composed of tea tree essential oil, sandalwood essential oil, cinnamon essential oil and lavender essential oil, and the mass ratio thereof is 6:8:5:2.

[0057] In this embodiment, the pH of the concentrated iodine mixed solution is 5.

[0058] In this embodiment, the quaternary ammonium salt is dioctadecyl dimethyl ammonium chloride and dioctadecyl dimethyl ammonium chloride, and the mass ratio of the two is 1:1.

[0059] A method for preparing a concentrated iodine mixed solution for animals comprises the following steps:

[0060] S1: adding iodine, potassium iodide and quaternary ammonium salt to the plant essential oil, mixing and stirring at 600 r / min for 10 min to obtain a mixture A;

[0061] S2: adding the Chinese herbal medicine mixture extract to the mixture A, mixing and stirring at 100 r / min for 30 min to obtain a mixture B;

[0062] S3: Adjust the pH of the mixture B to 5 to obtain a concentrated iodine mixture for veterinary use.

[0063] The rest is the same as in Example 1.

[0064] Example 4

[0065] A concentrated iodine mixed solution for animals comprises 5kg of iodine, 3kg of potassium iodide, 25kg of a traditional Chinese medicine mixture extract, 4kg of a quaternary ammonium salt, and 63kg of a plant essential oil.

[0066] In this embodiment, the Chinese medicine mixture consists of honeysuckle, garlic, houttuynia cordata, purslane, coptis root and sophora flavescens, and the mass ratio thereof is 4:6:1:2:6:5.

[0067] In the present embodiment, the plant essential oil is composed of tea tree essential oil, sandalwood essential oil, cinnamon essential oil and lavender essential oil, and the mass ratio thereof is 3:5:7:2.

[0068] In this embodiment, the quaternary ammonium salt is hexadecyldimethylbenzyl ammonium chloride, dihexadecyldimethylammonium bromide, and N-dialkyldimethylbenzyl, and the mass ratio thereof is 1:1:1.

[0069] The rest is the same as in Example 1.

[0070] Example 5

[0071] A concentrated iodine mixed solution for animals comprises 4kg of iodine, 2kg of potassium iodide, 18kg of a traditional Chinese medicine mixture extract, 5kg of a quaternary ammonium salt, and 71kg of a plant essential oil.

[0072] In this embodiment, the Chinese medicine mixture consists of honeysuckle, garlic, houttuynia cordata, purslane, coptis root and sophora flavescens, and the mass ratio thereof is 4:7:3:2:8:3.

[0073] In this embodiment, the preparation method of the Chinese medicine mixture extract is specifically as follows: weigh the Chinese medicine mixture according to the ratio, soak it in distilled water for 6 hours, boil it until boiling, simmer it over low heat for 10 hours, cool it, filter it, concentrate it to 1 / 3 of the volume, and vacuum freeze-dry it to obtain the Chinese medicine mixture extract.

[0074] In this embodiment, the mass volume ratio of the Chinese medicine mixture to distilled water is 1:8.

[0075] In the present embodiment, the plant essential oil is composed of tea tree essential oil, sandalwood essential oil, cinnamon essential oil and lavender essential oil, and the mass ratio thereof is 4:5:5:2.

[0076] The rest is the same as in Example 1.

[0077] Example 6

[0078] A concentrated iodine mixed solution for animals comprises 5kg of iodine, 5kg of potassium iodide, 15kg of a traditional Chinese medicine mixture extract, 1kg of a quaternary ammonium salt, and 74kg of a plant essential oil.

[0079] In this embodiment, the Chinese medicine mixture consists of honeysuckle, garlic, houttuynia cordata, purslane, coptis root and sophora flavescens, and the mass ratio thereof is 2:3:5:2:6:5.

[0080] In this embodiment, the plant essential oil is composed of tea tree essential oil, sandalwood essential oil, cinnamon essential oil and lavender essential oil, and the mass ratio thereof is 5:5:7:2.

[0081] The rest is the same as in Example 1.

[0082] Test Example 1 Sterilization Test

[0083] (1) The test method was carried out in accordance with the "Technical Specifications for Identification Tests of Veterinary Disinfectants" of the Ministry of Agriculture, and the bacterial suspension quantitative method was used.

[0084] (2) Test bacteria: including Escherichia coli, Staphylococcus aureus, Candida albicans, and Pasteurella multocida (poultry strain).

[0085] (3) Test steps:

[0086] ① Count the viable bacteria in the prepared bacterial solution, and then dilute it with 0.03 mol / L PBS buffer to a concentration of 10 6 ~10 7 / ml of test bacterial solution;

[0087] ② Pipette 0.5 ml of bacterial solution into 4.5 ml of concentrated iodine mixed solution for animals prepared in Examples 1 to 6;

[0088] ③ Place in a 20℃ water bath for 5 minutes;

[0089] ④ Take 1.0 ml of the above-mentioned bacterial and drug mixture and add it to 9.0 ml of neutralizing solution and mix;

[0090] ⑤ Replace the animal concentrated iodine solution with 0.03 mol / L PBS buffer and perform the above steps at the same time as the control group.

[0091] ⑥ Count the live bacteria and calculate the sterilization rate 10 minutes after neutralization.

[0092] (4) Test results: See Table 1-Table 6 for details.

[0093] Table 1 Killing effect of the product obtained in Example 1 on different strains

[0094]

[0095] Table 2 Killing effect of the product obtained in Example 2 on different strains

[0096]

[0097]

[0098] Table 3 Killing effect of the product obtained in Example 3 on different strains

[0099]

[0100] Table 4 Killing effect of the product obtained in Example 4 on different strains

[0101]

[0102] Table 5 Killing effect of the product obtained in Example 5 on different strains

[0103]

[0104]

[0105] Table 6 Killing effect of the product obtained in Example 6 on different strains

[0106]

[0107] Referring to Table 1-Table 6, when this product acts on Escherichia coli, at a dilution of 1:1600, the disinfection requirement can be achieved in 1 minute, and the sterilization rate is 100%. At a dilution of 1:6400, it takes 3 minutes to achieve the disinfection requirement; when acting on Staphylococcus aureus, at a dilution of 1:1600, the disinfection requirement can be achieved in 1 minute, and the sterilization rate is 100%. At a dilution of 1:3200, the disinfection requirement can be achieved within 3 minutes; when this product acts on Candida albicans, at a dilution of 1:1600, the prescribed sterilization purpose can be achieved in 1 minute, and at a dilution of 1:6400, the sterilization purpose can be achieved in 9 minutes; when acting on Pasteurella multocida (poultry strain), at a dilution of 1:800, the sterilization purpose can be achieved in 1 minute, and at a dilution of 1:1600, the sterilization purpose can be achieved in 9 minutes.

[0108] Test Example 2 Long-term stability test

[0109] The products obtained in Example 1 to Example 6 were placed in four temperatures of 90°C, 85°C, 80°C, and 80°C, and samples were taken every 1 hour to determine the iodine content in the disinfectant. The last sampling time was 10 hours. According to the change of iodine content, the temperature and decomposition rate change equation of each sample was listed to calculate the shelf life at 25°C.

[0110] According to the classical constant temperature method, the shelf life of the products prepared in Examples 1 to 6 is 2.25 years, 2.12 years, 2.29 years, and 2.31 years, respectively. It can be inferred that the disinfectant has a shelf life of more than 2 years.

[0111] Test Example 3 Toxicity Test

[0112] (1) Experimental Animals: 180 healthy mice were selected and randomly divided into 6 groups, designated as Experimental Group 1 to Experimental Group 6, with half of each group consisting of males and half females.

[0113] (2) Test drug: the product prepared in Example 1 to Example 6, 5000 mg / kg body weight.

[0114] (3) Experimental method: The drug was administered once by oral gavage to mice at a volume of 25 ml / kg. The mice were observed for 14 days after administration, and the symptoms of poisoning and death of the mice were recorded.

[0115] (4) Test results: See Table 7 for details.

[0116] Table 7 Toxicity test results of products obtained from Example 1 to Example 6

[0117]

[0118] Refer to Table 7 for the acute oral toxicity LD50 of this product to male and female mice. 50 >5000mg / kg body weight, which is practically non-toxic.

[0119] Test Example 4: Test on the Disinfection Effect of Pig Pens

[0120] (1) Test drugs: the product prepared in Example 1 and commercially available disinfectants.

[0121] (2) Test method: The number of bacteria in the pigsty floor, wall, water trough, food trough, and air was measured before and after disinfection, and the sterilization rate of the disinfectant was calculated. A commercial disinfectant was used as a control.

[0122] (3) Test results: See Table 8 for details.

[0123] Table 8 The disinfection effect of the product obtained in Example 1 and commercially available disinfectants on pig pens

[0124]

[0125] Referring to Table 8, the products prepared by the present invention were used to disinfect pig pens, and the disinfection effect was above 99%, which was better than commercially available disinfectants.

[0126] Test Example 5 Effect of this product on the growth performance of pigs

[0127] (1) Test drug: Same as Test Example 4.

[0128] (2) Test method:

[0129] Two groups of 24-day weaned piglets were selected, each with 15 piglets, and were raised in compartments without disinfection for 7 days. The product prepared in Example 1 and a commercially available disinfectant were sprayed and disinfected respectively, and the mental state (whether there were irritable performances such as arching and bumping), defecation (whether there were diarrhea), feeding (increase or decrease, prolonged feeding time), and skin changes (whether there were redness, swelling, or spots) of each group of animals were observed.

[0130] (3) Test results: After spray disinfection, the pigs' mental state, skin color and behavior were normal, their defecation was normal, and their feeding was normal.

[0131] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It is obvious to those skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic features of the present invention. Therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims are included in the present invention.

[0132] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. A concentrated iodine mixed solution for veterinary use, characterized in that: Based on 100 parts by weight, the composition comprises 2-5 parts by weight of iodine, 2-5 parts by weight of potassium iodide, 15-25 parts by weight of a Chinese herbal medicine mixture extract, 1-5 parts by weight of a quaternary ammonium salt, and the remainder of plant essential oil.

2. A concentrated iodine mixed solution for animals as claimed in claim 1, characterized in that: The traditional Chinese medicine mixture consists of honeysuckle, garlic, houttuynia cordata, purslane, coptis root and sophora flavescens.

3. A concentrated iodine mixed solution for animals as claimed in claim 2, characterized in that: The mass ratio of the honeysuckle, garlic, houttuynia cordata, purslane, coptis root and sophora flavescens is 2-5:3-10:1-5:2-4:5-8:3-5.

4. A concentrated iodine mixed solution for animals as claimed in claim 3, characterized in that: The preparation method of the Chinese medicine mixture extract is specifically as follows: weighing the Chinese medicine mixture according to the ratio, soaking it in distilled water for 5-8 hours, decocting it to boiling, then simmering it over low heat for 5-10 hours, cooling it, filtering it, concentrating it to 1 / 3 of its volume, and vacuum freeze-drying it to obtain the Chinese medicine mixture extract.

5. A concentrated iodine mixed solution for animals as claimed in claim 4, characterized in that: The mass volume ratio of the traditional Chinese medicine mixture to distilled water is 1:5-10.

6. A concentrated iodine mixed solution for animals as claimed in claim 5, characterized in that: The plant essential oil consists of tea tree essential oil, sandalwood essential oil, cinnamon essential oil and lavender essential oil.

7. A concentrated iodine mixed solution for animals as claimed in claim 6, characterized in that: The mass ratio of the tea tree essential oil, the sandalwood essential oil, the cinnamon essential oil and the lavender essential oil is 3-6:5-8:5-10:1-2.

8. A concentrated iodine mixed solution for animals as claimed in claim 7, characterized in that: The pH of the concentrated iodine mixed solution is 4-5.

9. A concentrated iodine mixed solution for animals as claimed in claim 7, characterized in that: The quaternary ammonium salt is one or more of benzalkonium bromide, dioctadecyl dimethyl ammonium chloride, dioctadecyl dimethyl ammonium chloride, hexadecyl dimethyl benzyl ammonium chloride, dihexadecyl dimethyl ammonium bromide, and N-dialkyl dimethyl benzyl.

10. A method for preparing the concentrated iodine mixed solution for animals as claimed in any one of claims 1 to 9, characterized in that: The steps include: S1: adding iodine, potassium iodide and quaternary ammonium salt to the plant essential oil, mixing and stirring at 400-600 r / min for 10-15 min to obtain a mixture A; S2: Add the Chinese herbal medicine mixture extract to the mixture A, mix and stir at 100-200 r / min for 20-30 min to obtain a mixture B; S3: Adjust the pH of the mixture B to 4-5 to obtain a concentrated iodine mixture for veterinary use.

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