Whitening composite composition containing cottonrose hibiscus leaf extract as well as preparation method and application of whitening composite composition
Through the combination of white root extract, mulberry bark extract, peony flower extract, hibiscus leaf extract, and papain and β-polyglucose, the problem of low tyrosinase inhibition rate in existing whitening skin care products is solved, and the significant effect of rapid whitening is achieved.
Patent Information
- Application Number
- CN202510794309.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-13
- Publication Date
- 2025-08-15
AI Technical Summary
The tyrosinase inhibition rate in existing whitening skin care products is not high, resulting in poor inhibition of melanin synthesis and is difficult to meet consumers' needs for rapid whitening.
A whitening complex composition containing hibiscus leaf extract is prepared by aging treatment using a combination of white hibiscus leaf extract, mulberry bark extract, peony flower extract, and hibiscus leaf extract, combined with papain and β-polyglucose.
It significantly inhibits tyrosinase activity, promotes skin metabolism, accelerates the excretion of melanin, achieves rapid whitening effect, and is easy to be absorbed by the skin. It has a simple preparation process and a significant whitening effect.
Abstract
Description
Technical Field
[0001] The invention relates to the field of skin care product raw materials, in particular to a whitening composite composition containing hibiscus mutabilis leaf extract. Background Art
[0002] Skin care products are products that care for the skin. Their main function is to restore the skin to health and improve the skin so that it appears in the state people want.
[0003] Whitening is one of the skin care effects pursued by most consumers. Existing skin care products mainly achieve the whitening effect by adding ingredients with whitening efficacy.
[0004] The principle of whitening is mainly to promote melanin metabolism and inhibit melanin synthesis. Promoting melanin metabolism mainly promotes the shedding of the skin's stratum corneum to expel melanin attached to the stratum corneum out of the skin. This process is a normal physiological phenomenon of the human body. Therefore, by improving the body's metabolic level, the replacement of the stratum corneum can be effectively promoted. Promoting melanin metabolism is relatively easy. However, if only melanin metabolism is promoted while ignoring the inhibition of melanin synthesis, the total amount of melanin will not decrease, and may even increase instead of decrease. Melanin is synthesized by melanocytes. The human body synthesizes melanin as a defense mechanism of the human skin. When the skin is damaged by ultraviolet rays, it will automatically synthesize a large amount of melanin in an attempt to protect the skin. Therefore, to inhibit melanin synthesis, it is necessary to block the melanin synthesis process. Existing whitening ingredients mainly hinder the melanin synthesis process by inhibiting the activity of tyrosinase. However, the tyrosinase inhibition rate of current whitening ingredients is not high. Although they can play a certain role in inhibiting melanin synthesis, the effect is still poor, resulting in low whitening efficiency and difficulty in meeting consumers' demand for rapid whitening. Therefore, there is still room for improvement. Summary of the Invention
[0005] In order to achieve a better and faster whitening effect, the present application provides a whitening composite composition containing Hibiscus mutabilis leaf extract.
[0006] In a first aspect, the present application provides a whitening composite composition containing Hibiscus mutabilis leaf extract, which adopts the following technical solution: A whitening composite composition containing Hibiscus mutabilis leaf extract comprises the following components in parts by weight: 18-22 parts of Bletilla striata root extract; 18-22 parts of mulberry bark extract; 18-22 parts of peony flower extract; 18-22 parts of Hibiscus mutabilis leaf extract; 18-22 parts of additives.
[0007] By adopting the above technical scheme, by using a combination of Bletilla striata root extract, mulberry bark extract, peony flower extract, and hibiscus mutabilis leaf extract, with the mutual cooperation of each active ingredient, it can significantly inhibit the activity of tyrosinase, thereby making the effect of inhibiting melanin synthesis more significant. The combination of Bletilla striata root extract, mulberry bark extract, peony flower extract, and hibiscus mutabilis leaf extract can also promote skin metabolism, accelerate the excretion of melanin, make the whitening effect take effect more quickly, and can well achieve the effect of rapid whitening.
[0008] Preferably, the auxiliary agent is a combination of papain and β-glucan.
[0009] By adopting the above technical solution and compounding papain and beta-glucan, the whitening efficacy can be further improved, making the whitening effect more significant.
[0010] Preferably, the mass ratio of papain to β-glucan is 9-11:9-11.
[0011] By adopting the above technical solution and specifically selecting the mass ratio of papain and β-glucan, whitening can be better assisted and the rapid whitening effect can be better.
[0012] Preferably, the Bletilla striata root extract, Morus alba bark extract, Paeonia lactiflora flower extract, and Hibiscus mutabilis leaf extract are all water-soluble extracts.
[0013] By adopting the above technical solution, by specifically selecting the white ampelopsis root extract, mulberry bark extract, peony flower extract, and hibiscus mutabilis leaf extract as water-soluble extracts, the active ingredients are easily absorbed by the skin, thereby achieving a better skin repair effect and a better rapid whitening effect.
[0014] In a second aspect, the present application provides a method for preparing a whitening composite composition containing Hibiscus mutabilis leaf extract, using the following technical solution: A method for preparing the above-mentioned whitening composite composition containing Hibiscus mutabilis leaf extract comprises the following steps: Step 1) dissolving the Bletilla striata root extract, the Morus alba bark extract, the Paeonia lactiflora flower extract, and the Hibiscus mutabilis leaf extract in water until completely dissolved to obtain a composite extract; Step 2), aging the composite extract for 28-30 days to obtain an aged solution; Step 3), concentrating and drying the aged liquid to obtain a composite extract; Step 4) adding an auxiliary agent to the composite extract and mixing uniformly to obtain a whitening composite composition containing the Hibiscus mutabilis leaf extract.
[0015] By adopting the above technical solution and aging the composite extract for 28-30 days, the active ingredients can cooperate with each other better, exert the whitening effect better, and achieve a more significant rapid whitening effect.
[0016] Preferably, in step 2), the composite extract is placed at a constant temperature of 32-36° C. for 28-30 days for aging.
[0017] By adopting the above technical solution and maintaining a constant temperature of 32-36°C, the active ingredients can better cooperate with each other and achieve a better rapid whitening effect.
[0018] In a third aspect, the present application provides an application of a whitening composite composition containing Hibiscus mutabilis leaf extract, using the following technical solution: An application of the above-mentioned whitening composite composition containing Hibiscus mutabilis leaf extract, wherein the whitening composite composition containing Hibiscus mutabilis leaf extract is added to skin care products to prepare skin care products with whitening effects.
[0019] By adopting the above technical solution, the prepared skin care products can achieve a rapid whitening effect and well meet the needs of consumers.
[0020] Preferably, the mass content of the whitening composite composition containing Hibiscus mutabilis leaf extract in the skin care product is 1-2%.
[0021] By adopting the above technical solution, the whitening composite composition containing Hibiscus mutabilis leaf extract is added to the skin care product formula with low process difficulty, easy production, and better rapid whitening effect.
[0022] In summary, this application has the following beneficial effects: 1. Since the present application adopts a compound of white peony root extract, mulberry bark extract, peony flower extract, and hibiscus mutabilis leaf extract, the mutual cooperation of each active ingredient can significantly inhibit the activity of tyrosinase, thereby making the effect of inhibiting melanin synthesis more significant. The combination of white peony root extract, mulberry bark extract, peony flower extract, and hibiscus mutabilis leaf extract can also promote skin metabolism and accelerate the excretion of melanin, so that the whitening effect is faster, and can well achieve the effect of rapid whitening.
[0023] 2. In the present application, the combination of papain and β-glucan is preferred to further enhance the whitening efficacy and make the whitening effect more significant.
[0024] 3. In the present application, it is preferred to age the composite extract at a constant temperature of 32-36°C for 28-30 days, so that the active ingredients can cooperate with each other better, exert the whitening effect better, and achieve a more significant rapid whitening effect. DETAILED DESCRIPTION
[0025] The present application is further described in detail below with reference to the embodiments.
[0026] Example 1 A whitening composite composition containing Hibiscus mutabilis leaf extract comprises the following components: Bletilla striata root extract, mulberry bark extract, peony flower extract, hibiscus mutabilis leaf extract, adjuvant.
[0027] The extract of Bletilla striata root was purchased from Hunan Saihe Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0028] Mulberry bark extract was purchased from Nanjing Dosfu Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0029] Peony flower extract was purchased from Nanjing Dosfu Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0030] Hibiscus mutabilis leaf extract was purchased from Nanjing Dosfu Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0031] The auxiliary agent is a compound of papain and beta-glucan.
[0032] Papain was purchased from Xi'an Tianzhixiang Company.
[0033] β-glucose was purchased from Xi'an Tianzhixiang Company.
[0034] The preparation method of the whitening composite composition containing Hibiscus mutabilis leaf extract comprises the following steps: Step 1) 18 kg of Ampelopsis root extract, 18 kg of Morus alba bark extract, 18 kg of Paeonia lactiflora flower extract, 18 kg of Hibiscus mutabilis leaf extract, and 400 kg of water were put into a stirred tank at a speed of 120 r / min and stirred for 15 min until completely dissolved to obtain a composite extract.
[0035] Step 2) The composite extract is placed at a constant temperature of 32° C. for 28 days for aging to obtain an aged solution.
[0036] Step 3) The aged liquid is concentrated by rotary evaporation at a concentration pressure of 0.01 MPa and a concentration temperature of 55° C. to a paste, and the paste is then dried by powder spraying to obtain a composite extract.
[0037] Step 4) 72 kg of the composite extract, 9 kg of papain, and 9 kg of β-glucan were added into a stirring kettle at a speed of 120 r / min and stirred for 30 min to obtain a whitening composite composition containing Hibiscus mutabilis leaf extract.
[0038] Example 2 A whitening composite composition containing Hibiscus mutabilis leaf extract comprises the following components: Bletilla striata root extract, mulberry bark extract, peony flower extract, hibiscus mutabilis leaf extract, adjuvant.
[0039] The extract of Bletilla striata root was purchased from Hunan Saihe Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0040] Mulberry bark extract was purchased from Nanjing Dosfu Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0041] Peony flower extract was purchased from Nanjing Dosfu Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0042] Hibiscus mutabilis leaf extract was purchased from Nanjing Dosfu Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0043] The auxiliary agent is a compound of papain and beta-glucan.
[0044] Papain was purchased from Xi'an Tianzhixiang Company.
[0045] β-glucose was purchased from Xi'an Tianzhixiang Company.
[0046] The preparation method of the whitening composite composition containing Hibiscus mutabilis leaf extract comprises the following steps: Step 1) 20 kg of Ampelopsis root extract, 20 kg of Morus alba bark extract, 20 kg of Paeonia lactiflora flower extract, 20 kg of Hibiscus mutabilis leaf extract, and 400 kg of water were put into a stirred tank at a speed of 120 r / min and stirred for 15 min until completely dissolved to obtain a composite extract.
[0047] Step 2) The composite extract is placed at a constant temperature of 34° C. for 29 days for aging to obtain an aged solution.
[0048] Step 3) The aged liquid is concentrated by rotary evaporation at a concentration pressure of 0.01 MPa and a concentration temperature of 58° C. to a paste, and the paste is then dried by powder spraying to obtain a composite extract.
[0049] Step 4) 80 kg of the composite extract, 10 kg of papain, and 10 kg of β-glucan are added into a stirring kettle at a speed of 120 r / min for 30 minutes to obtain a whitening composite composition containing Hibiscus mutabilis leaf extract.
[0050] Example 3 A whitening composite composition containing Hibiscus mutabilis leaf extract comprises the following components: Bletilla striata root extract, mulberry bark extract, peony flower extract, hibiscus mutabilis leaf extract, adjuvant.
[0051] The extract of Bletilla striata root was purchased from Hunan Saihe Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0052] Mulberry bark extract was purchased from Nanjing Dosfu Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0053] Peony flower extract was purchased from Nanjing Dosfu Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0054] Hibiscus mutabilis leaf extract was purchased from Nanjing Dosfu Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0055] The auxiliary agent is a compound of papain and beta-glucan.
[0056] Papain was purchased from Xi'an Tianzhixiang Company.
[0057] β-glucose was purchased from Xi'an Tianzhixiang Company.
[0058] The preparation method of the whitening composite composition containing Hibiscus mutabilis leaf extract comprises the following steps: Step 1) 22 kg of Ampelopsis root extract, 22 kg of Morus alba bark extract, 22 kg of Paeonia lactiflora flower extract, 22 kg of Hibiscus mutabilis leaf extract, and 400 kg of water were put into a stirred tank at a speed of 120 r / min and stirred for 15 min until completely dissolved to obtain a composite extract.
[0059] Step 2) The composite extract is placed at a constant temperature of 36° C. for 30 days for aging to obtain an aged solution.
[0060] Step 3) The aged liquid is concentrated by rotary evaporation at a concentration pressure of 0.01 MPa and a concentration temperature of 60° C. to a paste, and the paste is then dried by powder spraying to obtain a composite extract.
[0061] Step 4) 88 kg of the composite extract, 11 kg of papain, and 11 kg of β-glucan were added into a stirring kettle at a speed of 120 r / min and stirred for 30 minutes to mix evenly to obtain a whitening composite composition containing Hibiscus mutabilis leaf extract.
[0062] Comparative Example 1 A whitening composite composition containing Hibiscus mutabilis leaf extract, which differs from Example 2 only in that: The white peony root extract was replaced with an equal amount of angelica extract.
[0063] Angelica extract was purchased from Shanyang Lianfeng Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0064] Comparative Example 2 A whitening composite composition containing Hibiscus mutabilis leaf extract, which differs from Example 2 only in that: The mulberry bark extract was replaced with an equal amount of mulberry bark extract.
[0065] Mulberry bark extract was purchased from Xi'an Wuling Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0066] Comparative Example 3 A whitening composite composition containing Hibiscus mutabilis leaf extract, which differs from Example 2 only in that: An equal amount of licorice extract was used to replace the peony flower extract.
[0067] Licorice extract was purchased from Jiangsu Jiujia Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0068] Comparative Example 4 A whitening composite composition containing Hibiscus mutabilis leaf extract, which differs from Example 2 only in that: Replace hibiscus leaf extract with grape seed extract in equal amounts.
[0069] Grape seed extract was purchased from Lanzhou Waterless Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0070] Comparative Example 5 A whitening composite composition containing Hibiscus mutabilis leaf extract, which differs from Example 2 only in that: The white peony root extract was replaced with an equal amount of angelica extract.
[0071] The mulberry bark extract was replaced with an equal amount of mulberry bark extract.
[0072] An equal amount of licorice extract was used to replace the peony flower extract.
[0073] Replace hibiscus leaf extract with grape seed extract in equal amounts.
[0074] Angelica extract was purchased from Shanyang Lianfeng Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0075] Mulberry bark extract was purchased from Xi'an Wuling Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0076] Licorice extract was purchased from Jiangsu Jiujia Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0077] Grape seed extract was purchased from Lanzhou Waterless Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0078] Comparative Example 6 A whitening composite composition containing Hibiscus mutabilis leaf extract, which differs from Example 2 only in that: The preparation method of the whitening composite composition containing Hibiscus mutabilis leaf extract comprises the following steps: Step 1) 20 kg of Ampelopsis root extract, 20 kg of Morus alba bark extract, 20 kg of Paeonia lactiflora flower extract, 20 kg of Hibiscus mutabilis leaf extract, and 400 kg of water were put into a stirred tank at a speed of 120 r / min and stirred for 15 min until completely dissolved to obtain a composite extract.
[0079] Step 2) The composite extract is concentrated by rotary evaporation at a concentration pressure of 0.01 MPa and a concentration temperature of 58° C. to a paste, and the paste is then dried by powder spraying to obtain a composite extract.
[0080] Step 3) 80 kg of the composite extract, 10 kg of papain, and 10 kg of β-glucan are added into a stirring kettle at a speed of 120 r / min and stirred for 30 minutes to mix evenly to obtain a whitening composite composition containing Hibiscus mutabilis leaf extract.
[0081] Experiment 1 According to T / GDCA 006-2021 "Test method for inhibition of tyrosinase activity by cosmetic raw materials (in vitro method)", the tyrosinase inhibition rate (%) of the test samples prepared from the whitening composite composition containing Hibiscus mutabilis leaf extract in each embodiment and comparative example was tested.
[0082] Sample to be tested: 2 g of the whitening composite composition containing Hibiscus mutabilis leaf extract and 98 g of deionized water were mixed evenly to obtain a sample to be tested.
[0083] The experimental data of Experiment 1 are detailed in Table 1.
[0084] Table 1 Tyrosinase inhibition rate (%) Example 1 91.3 Example 2 92.5 Example 3 92.1 Comparative Example 1 75.2 Comparative Example 2 70.8 Comparative Example 3 76.4 Comparative Example 4 73.7 Comparative Example 5 68.3 Comparative Example 6 86.9 According to the data comparison of each embodiment and comparative example in Table 1, the tyrosinase inhibition rate of each embodiment is significantly higher than that of each comparative example. It can be seen that each embodiment can have a better effect of increasing tyrosinase activity through the compounding of Bletilla striata root extract, Morus alba bark extract, Paeonia lactiflora flower extract, and Hibiscus mutabilis leaf extract, thereby better inhibiting melanin synthesis and achieving a faster whitening effect.
[0085] Although the tyrosinase inhibition rate of Comparative Example 6 is higher than that of Comparative Examples 1-5, it is lower than that of each embodiment, which proves that the aging step can improve the synergistic effect of the white ampelopsis root extract, mulberry bark extract, peony flower extract, and hibiscus mutabilis leaf extract, which helps to improve the rapid whitening effect.
[0086] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make non-creative modifications to the present embodiment as needed, but as long as they are within the scope of the claims of the present application, they are protected by the patent law.
Claims
1. A whitening composite composition containing Hibiscus mutabilis leaf extract, characterized in that: The composition includes the following parts by weight: 18-22 parts of Bletilla striata root extract; 18-22 parts of mulberry bark extract; 18-22 parts of peony flower extract; 18-22 parts of Hibiscus mutabilis leaf extract; 18-22 parts of additives.
2. The whitening composite composition containing Hibiscus mutabilis leaf extract according to claim 1, characterized in that: The auxiliary agent is a compound of papain and beta-glucan.
3. The whitening composite composition containing Hibiscus mutabilis leaf extract according to claim 2, characterized in that: The mass ratio of the papain to β-glucan is 9-11:9-11.
4. The whitening composite composition containing Hibiscus mutabilis leaf extract according to claim 3, characterized in that: The white ampelopsis root extract, mulberry bark extract, peony flower extract and hibiscus mutabilis leaf extract are all water-soluble extracts.
5. A method for preparing the whitening composite composition containing the Hibiscus mutabilis leaf extract according to any one of claims 1 to 4, characterized in that: The following steps are involved: Step 1) dissolving the Bletilla striata root extract, the Morus alba bark extract, the Paeonia lactiflora flower extract, and the Hibiscus mutabilis leaf extract in water until completely dissolved to obtain a composite extract; Step 2), aging the composite extract for 28-30 days to obtain an aged solution; Step 3), concentrating and drying the aged liquid to obtain a composite extract; Step 4) adding an auxiliary agent to the composite extract and mixing them evenly to obtain a whitening composite composition containing Hibiscus mutabilis leaf extract.
6. The method for preparing a whitening composite composition containing Hibiscus mutabilis leaf extract according to claim 5, characterized in that: In the step 2), the composite extract is placed at a constant temperature of 32-36° C. for 28-30 days for aging.
7. A use of the whitening composite composition containing the Hibiscus mutabilis leaf extract according to any one of claims 1 to 4, characterized in that: The whitening composite composition containing the Hibiscus mutabilis leaf extract is added into skin care products to prepare skin care products with whitening effects.
8. The use of a whitening composite composition containing Hibiscus mutabilis leaf extract according to claim 7, characterized in that: The mass content of the whitening composite composition containing the Hibiscus mutabilis leaf extract in skin care products is 1-2%.