Cleaning and acne-removing composition and application thereof
Through the composition of gluconolactone, glycolic acid, pyrrolidone carboxylic acid and glycolipid, the existing shower gel has been solved, and the effective and gentle cleaning of acne removal shower gel is provided, which improves the acne removal effect and user experience.
Patent Information
- Application Number
- CN202510887180.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-06-30
- Publication Date
- 2025-08-19
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The existing shower gel has shortcomings in cleaning and acne removal effects. Traditional surfactants are not clean and toxic. The fatty acid soap-based shower gel is too alkaline to stimulate the skin. The existing acne removal components are single, and the cleaning and acne removal effects cannot be fully achieved.
The combination of gluconolactone, glycolic acid, pyrrolidone carboxylic acid and glycolipid is used to improve the cleaning and acne removal performance through synergistic effects, and surfactant, moisturizing agent and skin conditioner are added to prepare acne removal shower gel.
It has strong cleansing power, significant and gentle acne removal effect, anti-itching effects, and enhances the skin feeling. It is suitable for all skin types.
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Abstract
Description
Technical Field
[0001] The present invention belongs to the technical field of cosmetics, and in particular relates to a cleaning and anti-acne composition and application thereof. Background Art
[0002] Shower gel has become one of the most widely used products in the skin care industry. With the improvement of people's living standards, people's requirements for shower gel are getting higher and higher, such as the user experience and the ability to cleanse the skin.
[0003] While traditional surfactant-based body washes can meet basic cleansing needs, they can no longer satisfy modern consumers' pursuit of a higher quality of life due to various issues during use, such as poor rinsing and the generation of trace toxic substances. While fatty acid soap-based body washes offer better rinsing properties, their high alkalinity can easily irritate the skin, causing dryness, tightness, itching, inflammation, and redness.
[0004] CN119499138A discloses an oil-controlling, moisturizing and anti-acne shower gel and its preparation method. According to parts by mass, the raw materials of the oil-controlling, moisturizing and anti-acne shower gel include: 1. a skin conditioner including 0.1-5 parts of cedar hydrosol, 0.1-3 parts of hydrolyzed starch, 0.01-3 parts of water-locking magnetite and 0.1-1 parts of capryloyl glycine; 2. an anti-acne agent is piroctone olamine salt; 3. a surfactant is selected from one or more of anionic surfactants, cationic surfactants, amphoteric surfactants and nonionic surfactants. The oil-controlling, moisturizing and anti-acne shower gel achieves significant anti-acne and oil-control effects through piroctone olamine salt and cedar hydrosol, while also having excellent moisturizing ability. However, the anti-acne component in this formula is relatively single, and it is impossible to fully achieve cleaning and anti-acne effects.
[0005] Therefore, developing a shower gel with mild performance, strong cleaning power and acne-removing effect has become one of the technical problems to be solved urgently. Summary of the Invention
[0006] In view of the shortcomings of the prior art, the present invention aims to provide a cleansing and anti-acne composition and its application. The composition has mild properties, strong cleaning power, and excellent acne removal effect.
[0007] In order to achieve the purpose of the invention, the present invention adopts the following technical solutions:
[0008] In a first aspect, the present invention provides a cleansing and anti-acne composition, comprising gluconolactone, glycolic acid, pyrrolidone carboxylic acid, and glycolipid.
[0009] Gluconolactone is an ester formed by the dehydration of the carboxyl group of gluconic acid and the hydroxyl group within the molecule. It is known as a second-generation fruit acid and has benefits such as moisturizing, improving fine lines and wrinkles, sagging skin, uneven skin tone, and treating acne. Hydroxyacetic acid is a type of fruit acid that can effectively penetrate the skin and stimulate cell vitality. It has been widely used in skin rejuvenation, whitening, anti-acne, hair care, and nail art. Pyrrolidone carboxylic acid is an amino acid derivative that can be used as a moisturizer, skin conditioner, and antistatic agent. It can improve sensitive skin and oily skin, making the skin appear firmer and more elastic. Glycolipids are lipid compounds containing sugar ligands that have excellent biocompatibility and possess outstanding surface activity and emulsifying activity.
[0010] The present invention creatively discovers that gluconolactone, glycolic acid, pyrrolidone carboxylic acid and glycolipids have significant synergistic effects in cleansing and removing acne. The four cooperate with each other and synergistically enhance the acne-removing performance of the composition, while also having an antipruritic effect and improving the skin feel during use.
[0011] Preferably, the cleansing and anti-acne composition comprises, by weight, 1-10 parts of gluconolactone, 0.5-5 parts of glycolic acid, 0.5-5 parts of pyrrolidone carboxylic acid and 1-10 parts of glycolipid.
[0012] Among them, the specific point values in 1-10 parts can be selected from 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, etc., and the specific point values in 0.5-5 parts can be selected from 0.5 parts, 1 part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, etc.
[0013] Based on the synergistic relationship among the components in the composition, when gluconolactone, glycolic acid, pyrrolidone carboxylic acid and glycolipid are compounded in the above-mentioned mass fractions, the cleansing and acne-removing effect of the composition can be better exerted.
[0014] Preferably, the glycolipid comprises any one or a combination of at least two of rhamnolipid, glucose lipid, mannoseerythritol lipid or sophorolipid.
[0015] Preferably, the glycolipids include rhamnolipids, glucose lipids, mannose erythritol lipids and sophorolipids.
[0016] Rhamnolipids are composed of hydrophilic rhamnose (1-2 molecules of rhamnose rings constitute the hydrophilic group) and hydrophobic saturated or unsaturated fatty acids (1-2 molecules of fatty acids with different carbon chain lengths constitute the hydrophobic group). They are a surfactant widely used in cosmetics with excellent surface activity, emulsifying activity, skin compatibility and low irritation, which can improve the texture and efficacy of products. The hydrophilic group of glucose lipids contains only one β-D-glucose. It is a green biosurfactant with excellent fat solubility. Mannoerythritol lipids use 4-0-β-D-pyranose-meso-erythritol as the hydrophilic part and the acetyl group on the fatty chain or sugar group as the hydrophobic part, and also have good surface activity. Sophorolipid molecules are composed of hydrophilic and hydrophobic parts. The hydrophobic part is fatty acid and the hydrophilic part is sophorose, which can play a role in dispersion, wetting, emulsification, etc.
[0017] The present invention creatively discovered that rhamnolipids, glucose lipids, mannose erythritol lipids and sophorolipids have significant synergistic effects in cleansing and removing acne, and can better interact with gluconolactone, glycolic acid and pyrrolidone carboxylic acid, thereby improving the overall cleansing and removing acne performance of the composition and improving the skin feel during use.
[0018] Preferably, the mass ratio of the rhamnolipid, glucose lipid, mannoerythritol lipid and sophorolipid is (1-5):(5-10):(3-7):(1-5).
[0019] Among them, the specific point values in 1-5 can be selected from 1, 2, 3, 4, 5, etc., the specific point values in 5-10 can be selected from 5, 6, 7, 8, 9, 10, etc., and the specific point values in 3-7 can be selected from 3, 4, 5, 6, 7, etc.
[0020] Based on the synergistic relationship between rhamnolipids, glucose lipids, mannose erythritol lipids and sophorolipids, when the glycolipids are compounded in the above-mentioned proportions, the cleansing and acne-removing effects of the glycolipids can be better exerted.
[0021] In a second aspect, the present invention provides a use of the cleansing and anti-acne composition according to the first aspect in cosmetics.
[0022] In a third aspect, the present invention provides a cleansing and anti-acne shower gel, comprising the cleansing and anti-acne composition of the first aspect, a surfactant, a moisturizer, a skin conditioner, and a solvent.
[0023] Preferably, the cleansing and anti-acne shower gel comprises, by mass, 1-5 parts of the cleansing and anti-acne composition of the first aspect, 10-30 parts of a surfactant, 5-10 parts of a moisturizer, 1-5 parts of a skin conditioner, and 50-85 parts of a solvent.
[0024] Among them, the specific point values in 1-5 portions can be selected from 1 portion, 2 portions, 3 portions, 4 portions, 5 portions, etc., the specific point values in 10-30 portions can be selected from 10 portions, 15 portions, 20 portions, 25 portions, 30 portions, etc., the specific point values in 5-10 portions can be selected from 5 portions, 6 portions, 7 portions, 8 portions, 9 portions, 10 portions, etc., and the specific point values in 50-85 portions can be selected from 50 portions, 55 portions, 60 portions, 65 portions, 70 portions, 75 portions, 80 portions, 85 portions, etc.
[0025] Preferably, the surfactant includes any one of sodium laureth sulfate, sodium lauryl sulfate, sodium lauroyl sarcosinate or cocamidopropyl betaine, or a combination of at least two thereof.
[0026] Preferably, the humectant comprises glycerin and / or sodium PCA.
[0027] Preferably, the skin conditioning agent comprises any one or a combination of at least two of sodium polyaspartate, butylene glycol, pentylene glycol, hexylene glycol or tocopherol.
[0028] Preferably, the solvent comprises water.
[0029] In a fourth aspect, the present invention provides a method for preparing the cleansing and anti-acne shower gel according to the third aspect, the preparation method comprising the following steps:
[0030] The emulsifier and the moisturizer are mixed and homogenized to obtain a mixed liquid; and then the mixed liquid is mixed and stirred with the cleansing and anti-acne composition, the skin conditioner and the solvent to obtain the cleansing and anti-acne shower gel.
[0031] Preferably, the speed of the mixing and homogenizing before obtaining the mixed liquid is 1000-3000 rpm, the temperature of the mixing and homogenizing is 80-90° C., and the time of the mixing and homogenizing is 20-40 min.
[0032] Preferably, the mixing and stirring speed before obtaining the cleansing and anti-acne shower gel is 10-40 rpm, the mixing and stirring temperature is 45-50° C., and the mixing and stirring time is 20-40 min.
[0033] Among them, the specific point values in 1000-3000rpm can be selected from 1000rpm, 1500rpm, 2000rpm, 2500rpm, 3000rpm, etc., the specific point values in 10-40rpm can be selected from 10rpm, 20rpm, 30rpm, 40rpm, etc., the specific point values in 80-90℃ can be selected from 80℃, 82℃, 84℃, 86℃, 88℃, 90℃, etc., the specific point values in 45-50℃ can be selected from 45℃, 46℃, 47℃, 48℃, 49℃, 50℃, etc., and the specific point values in 20-40min can be selected from 20min, 25min, 30min, 35min, 40min, etc.
[0034] The numerical range described in the present invention includes not only the point values listed above, but also any point values between the above numerical ranges that are not listed. Due to space limitations and for the sake of simplicity, the present invention no longer exhaustively lists the specific point values included in the range.
[0035] Compared with the prior art, the present invention has the following beneficial effects:
[0036] The present invention utilizes the synergistic effect of gluconolactone, glycolic acid, pyrrolidone carboxylic acid and glycolipids in cleaning and removing acne, so that the composition has excellent cleaning and removing acne performance, is less irritating, has antipruritic effect, and has good skin feel when used.
[0037] Furthermore, in terms of the selection of glycolipids, the present invention creatively discovered that rhamnolipids, glucose lipids, mannose erythritol lipids and sophorolipids have significant synergistic effects in cleansing and removing acne, and can better interact with gluconolactone, glycolic acid and pyrrolidone carboxylic acid, thereby improving the overall cleansing and removing acne performance of the composition and improving the skin feel during use.
[0038] Furthermore, when rhamnolipids, glucose lipids, mannose erythritol lipids and sophorolipids are compounded in a mass ratio of (1-5):(5-10):(3-7):(1-5), the synergistic effect of the four glycolipids can be better enhanced, thereby improving the overall cleansing and anti-acne performance of the composition. DETAILED DESCRIPTION
[0039] In order to further illustrate the technical means and effects adopted by the present invention, the technical solutions of the present invention are further described below in conjunction with the preferred embodiments of the present invention, but the present invention is not limited to the scope of the embodiments.
[0040] The sources of the components / raw materials in the following embodiments are shown in Table 1.
[0041] Table 1
[0042]
[0043] Example 1
[0044] This embodiment provides a cleansing and anti-acne composition, comprising 5 parts of gluconolactone, 3 parts of glycolic acid, 3 parts of pyrrolidone carboxylic acid, and 5 parts of glycolipids (rhamnolipid, glucose lipid, mannose erythritol lipid, and sophorolipid in a mass ratio of 3:7:5:3).
[0045] Example 2
[0046] This embodiment provides a cleansing and anti-acne composition, comprising 1 part of gluconolactone, 5 parts of glycolic acid, 5 parts of pyrrolidone carboxylic acid, and 1 part of glycolipids (rhamnolipid, glucose lipid, mannose erythritol lipid, and sophorolipid in a mass ratio of 1:10:3:5).
[0047] Example 3
[0048] This embodiment provides a cleansing and anti-acne composition, comprising 10 parts of gluconolactone, 0.5 parts of glycolic acid, 0.5 parts of pyrrolidone carboxylic acid, and 10 parts of glycolipids (rhamnolipid, glucose lipid, mannose erythritol lipid, and sophorolipid in a mass ratio of 5:5:7:1).
[0049] Example 4
[0050] This embodiment provides a cleansing and anti-acne composition, which differs from Example 1 only in that the total mass fraction of glycolipids is kept unchanged, and the glycolipids are replaced with glucose lipids, mannose erythritol lipids and sophorolipids in a mass ratio of 7:5:3, and the rest of the formula is consistent with Example 1.
[0051] Example 5
[0052] This embodiment provides a cleansing and anti-acne composition, which differs from Example 1 only in that the total mass fraction of glycolipids is kept unchanged, and the glycolipids are replaced with rhamnolipids, mannose erythritol lipids and sophorolipids in a mass ratio of 3:5:3, and the rest of the formula is consistent with Example 1.
[0053] Example 6
[0054] This embodiment provides a cleansing and anti-acne composition, which differs from Example 1 only in that the total mass fraction of glycolipids is kept unchanged, and the glycolipids are replaced with rhamnolipids, glucose lipids and sophorolipids in a mass ratio of 3:7:3, and the rest of the formula is consistent with Example 1.
[0055] Example 7
[0056] This embodiment provides a cleansing and anti-acne composition, which differs from Example 1 only in that the total mass fraction of glycolipids is kept unchanged, and the glycolipids are replaced with rhamnolipids, glucose lipids, and mannose erythritol lipids in a mass ratio of 3:7:5. The rest of the formula remains the same as in Example 1.
[0057] Example 8
[0058] This embodiment provides a cleansing and anti-acne composition, which differs from Example 1 only in that the total mass fraction of glycolipids is kept unchanged, and the mass ratio of rhamnolipid, glucose lipid, mannose erythritol lipid and sophorolipid is adjusted to 6:12:2:0.5, and the rest of the formula is consistent with Example 1.
[0059] Example 9
[0060] This embodiment provides a cleansing and anti-acne composition, which differs from Example 1 only in that the total mass fraction of glycolipids is kept unchanged, and the mass ratio of rhamnolipid, glucose lipid, mannose erythritol lipid and sophorolipid is adjusted to 0.5:3:8:7, and the rest of the formula is consistent with Example 1.
[0061] Comparative Example 1
[0062] This comparative example provides a composition, which differs from Example 1 only in that glycolipid is removed from the composition, that is, the formula is: 5 parts of gluconolactone, 3 parts of glycolic acid and 3 parts of pyrrolidone carboxylic acid.
[0063] Comparative Example 2
[0064] This comparative example provides a composition, which differs from Example 1 only in that pyrrolidone carboxylic acid is removed from the composition, that is, the formula is: 5 parts of gluconolactone, 3 parts of glycolipids and 5 parts of glycolipids (rhamnolipid, glucose lipid, mannose erythritol lipid and sophorolipid in a mass ratio of 3:7:5:3).
[0065] Comparative Example 3
[0066] This comparative example provides a composition, which differs from Example 1 only in that glycolic acid is removed from the composition, that is, the formula is: 5 parts of gluconolactone, 3 parts of pyrrolidone carboxylic acid and 5 parts of glycolipids (rhamnolipid, glucose lipid, mannose erythritol lipid and sophorolipid in a mass ratio of 3:7:5:3).
[0067] Comparative Example 4
[0068] This comparative example provides a composition, which differs from Example 1 only in that gluconolactone is removed from the composition, that is, the formula is: 3 parts of glycolic acid, 3 parts of pyrrolidone carboxylic acid and 5 parts of glycolipids (rhamnolipid, glucose lipid, mannose erythritol lipid and sophorolipid in a mass ratio of 3:7:5:3).
[0069] Application Example 1
[0070] This application example provides a cleansing and anti-acne shower gel, which includes 5 parts of the cleansing and anti-acne composition of Example 1, 20 parts of a surfactant (sodium laureth sulfate, sodium lauryl sulfate, sodium lauroyl sarcosinate and cocamidopropyl betaine in a mass ratio of 10:1:2:2), 7 parts of a moisturizer (glycerin and sodium PCA in a mass ratio of 3:5), 1 part of a skin conditioner (sodium polyaspartate, 1,2-butylene glycol, 1,2-pentanediol, 1,2-hexanediol and tocopherol in a mass ratio of 10:8:2:1:1), and the balance is a solvent (water).
[0071] The preparation process is:
[0072] The emulsifier and moisturizer were mixed and homogenized at 85° C. and 2000 rpm for 30 minutes to obtain a mixed solution; then the mixture was cooled to 47° C. and mixed with the cleansing and anti-acne composition, skin conditioner and solvent at 20 rpm for 30 minutes to obtain a cleansing and anti-acne shower gel.
[0073] Application Example 2
[0074] This application example provides a cleansing and anti-acne shower gel, which includes 3 parts of the cleansing and anti-acne composition of Example 2, 30 parts of a surfactant (sodium laureth sulfate, sodium lauryl sulfate, sodium lauroyl sarcosinate and cocamidopropyl betaine in a mass ratio of 6:2:2:0.5), 10 parts of a moisturizer (glycerin and sodium PCA in a mass ratio of 1:1), 3 parts of a skin conditioner (sodium polyaspartate, 1,2-butylene glycol, 1,2-pentanediol, 1,2-hexanediol and tocopherol in a mass ratio of 5:1:3:0.5:1), and the balance is a solvent (water).
[0075] The preparation process is:
[0076] The emulsifier and moisturizer were mixed and homogenized at 90° C. and 1000 rpm for 40 minutes to obtain a mixed solution; then the mixture was cooled to 50° C. and mixed with the cleansing and anti-acne composition, the skin conditioner (and the solvent) at 40 rpm for 20 minutes to obtain a cleansing and anti-acne shower gel.
[0077] Application Example 3
[0078] This application example provides a cleansing and anti-acne shower gel, which includes 1 part of the cleansing and anti-acne composition of Example 3, 10 parts of surfactants (sodium laureth sulfate, sodium lauryl sulfate, sodium lauroyl sarcosinate and cocamidopropyl betaine in a mass ratio of 5:3:2:3), 5 parts of moisturizers (glycerin and sodium PCA in a mass ratio of 5:1), 5 parts of skin conditioners (sodium polyaspartate, 1,2-butylene glycol, 1,2-pentanediol, 1,2-hexanediol and tocopherol in a mass ratio of 5:3:0.5:0.8:0.5), and the balance is solvent (water).
[0079] The preparation process is:
[0080] The emulsifier and moisturizer were mixed and homogenized at 80°C and 3000 rpm for 20 minutes to obtain a mixed solution; then the mixture was cooled to 45°C and mixed with the cleansing and anti-acne composition, skin conditioner and solvent at 10 rpm for 40 minutes to obtain a cleansing and anti-acne shower gel.
[0081] Application Examples 4-9
[0082] Application Examples 4-9 each provide a cleansing and anti-acne shower gel, which differs from Application Example 1 only in that the cleansing and anti-acne shower gel of Example 1 is replaced by the cleansing and anti-acne compositions of Examples 4-9 of equal mass, respectively, and the remaining formulas and process parameters remain consistent with Application Example 1.
[0083] Comparative Application Examples 1-4
[0084] Comparative Application Examples 1-4 each provide a shower gel, the difference between which is respectively different from Application Example 1 is that the cleansing and anti-acne shower gel of Example 1 is replaced by the compositions of Comparative Examples 1-4 of equal mass, respectively, and the rest of the formula and process parameters remain the same as those of Application Example 1.
[0085] Test Example 1
[0086] Acne removal effect test:
[0087] Propionibacterium acnes is the main factor causing pimples and acne on the skin. By testing the inhibitory effect of shower gel on Propionibacterium acnes, the acne-removing effect of shower gel is evaluated.
[0088] (1) Test sample: The shower gel obtained in each application example and comparative application example was diluted with deionized water to a concentration of 20 wt %.
[0089] (2) Test method:
[0090] Soak a filter paper with a diameter of 5 mm and a thickness of 2.5 mm in a sample solution with a concentration of 20 wt%. After saturation, take it out to obtain an antibacterial sample sheet. Use a sterile cotton swab to dip a sample with a concentration of about 6.8 × 10 5 A suspension of P. acnes at a concentration of 500 CFU / mL was evenly applied three times to the surface of a culture plate. The plate was covered and allowed to stand at room temperature for 5 minutes. Using sterile tweezers, an antibacterial sample was placed on the surface of the plate, gently pressing the sample to adhere to the surface. The plate was then covered and incubated at 37°C ± 0.5°C for 15 hours. The results were observed and the size of the inhibition zone was measured using a vernier caliper and recorded. Each test was repeated five times in parallel, and the average value was calculated. The results of the inhibition zone size test are shown in Table 2.
[0091] Table 2
[0092]
[0093]
[0094] Test Example 2
[0095] Human sensory evaluation:
[0096] (1) Test sample: the shower gel obtained from each application example and comparative application example.
[0097] (2) Subjects: 130 volunteers, 65 males and 65 females, were randomly recruited. They had different skin itching problems due to factors such as bacterial infection, mite infection, eczema, and self-sensitivity. They were randomly divided into 13 groups, with 10 people in each group. Each group used the shower gel obtained from the application example and the control application example respectively.
[0098] (3) Test method: Use the corresponding test sample to cleanse the skin every day during the shower for 4 consecutive weeks. Evaluate the effectiveness of the shower gel based on its pruritus relief, cleansing power, and smoothness.
[0099] The scoring criteria for skin sensation are shown in Table 3, and the sensory evaluation results after the subjects used each test sample are shown in Table 4.
[0100] Table 3
[0101]
[0102]
[0103] Table 4
[0104] sample score Application Example 1 5.0 Application Example 2 4.8 Application Example 3 4.5 Application Example 4 3.6 Application Example 5 4.2 Application Example 6 3.7 Application Example 7 3.6 Application Example 8 4.2 Application Example 9 4.0 Comparative Application Example 1 3.0 Comparative Application Example 2 2.1 Comparative Application Example 3 2.6 Comparative Application Example 4 2.4
[0105] It can be seen from the test data in Tables 2 to 4 that the shower gel of the present invention has excellent acne-removing, itching-relieving and cleansing effects, and leaves the skin feeling smooth.
[0106] From the comparison of the data of Application Example 1 and Comparative Application Examples 1-4, it can be seen that gluconolactone, glycolic acid, pyrrolidone carboxylic acid and glycolipids have a significant synergistic effect in cleansing and removing acne, and can relieve skin itching and improve skin feel.
[0107] From the comparison of the data of Application Example 1 and Application Examples 4-7, it can be seen that in terms of the selection of glycolipids, rhamnolipids, glucose lipids, mannose erythritol lipids and sophorolipids have significant synergistic effects. The four components are used together to enhance the overall cleansing and acne-removing performance of the composition, and can better relieve skin itching and make the skin feel smooth.
[0108] From the comparison of the data of Application Example 1 and Application Examples 8-9, it can be seen that when rhamnolipids, glucose lipids, mannose erythritol lipids and sophorolipids are compounded in a mass ratio of (1-5): (5-10): (3-7): (1-5), the synergistic effect of the four glycolipids can be better enhanced, and the overall cleansing and anti-acne performance and skin feel of the composition can be improved.
[0109] Test Example 3
[0110] Safety testing:
[0111] (1) Test sample: the shower gel obtained from each application example and comparative application example.
[0112] (2) Test population: The same test population as in Test Example 2 was selected for safety testing.
[0113] (3) Test method:
[0114] After cleaning the subject's back, apply a 5g patch containing the test sample to the selected area on the back using non-irritating adhesive tape. Once applied, gently press the patch evenly onto the skin with your fingers for 48 hours. The subject should keep the patch area dry and avoid strenuous exercise, scratching, or prolonged sunlight. After 48 hours, remove the patch and mark the area. After 30 minutes, once the indentation has disappeared, perform the assessment under adequate lighting.
[0115] The grading standards for adverse skin reactions are shown in Table 5, and the test results are shown in Table 6.
[0116] Table 5
[0117]
[0118]
[0119] Table 6
[0120]
[0121] It can be seen from the data in Table 6 that the shower gel of the present invention is mild and non-irritating, and is suitable for use by people with sensitive skin.
[0122] The applicant declares that the present invention is illustrated by the above-described embodiments, but the present invention is not limited to the above-described embodiments. This does not mean that the present invention must rely on the above-described embodiments in order to be implemented. Those skilled in the art should understand that any improvements to the present invention, equivalent replacements for raw materials in the present invention, additions of auxiliary ingredients, and selection of specific methods, etc., fall within the scope of protection and disclosure of the present invention.
[0123] The preferred embodiments of the present invention are described in detail above. However, the present invention is not limited to the specific details in the above embodiments. Within the technical concept of the present invention, various simple modifications can be made to the technical solution of the present invention, and these simple modifications all fall within the scope of protection of the present invention.
[0124] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any appropriate manner without contradiction. In order to avoid unnecessary repetition, the present invention will not further describe various possible combinations.
Claims
1. A cleaning and anti-acne composition, characterized in that: The cleansing and anti-acne composition comprises gluconolactone, glycolic acid, pyrrolidone carboxylic acid and glycolipid.
2. The cleansing and anti-acne composition according to claim 1, characterized in that: In parts by mass, the cleansing and anti-acne composition comprises 1-10 parts of gluconolactone, 0.5-5 parts of glycolic acid, 0.5-5 parts of pyrrolidone carboxylic acid and 1-10 parts of glycolipid.
3. The cleansing and anti-acne composition according to claim 1 or 2, characterized in that: The glycolipids include any one or a combination of at least two of rhamnolipids, glucose lipids, mannose erythritol lipids or sophorolipids; Preferably, the glycolipids include rhamnolipids, glucose lipids, mannose erythritol lipids and sophorolipids.
4. The cleansing and anti-acne composition according to claim 3, characterized in that: The mass ratio of the rhamnolipid, glucose lipid, mannoerythritol lipid and sophorolipid is (1-5):(5-10):(3-7):(1-5).
5. Use of the cleansing and anti-acne composition according to any one of claims 1 to 4 in cosmetics.
6. A cleansing and anti-acne shower gel, characterized in that: The cleansing and anti-acne shower gel comprises the cleansing and anti-acne composition according to any one of claims 1 to 4, a surfactant, a moisturizer, a skin conditioner, and a solvent.
7. The cleansing and anti-acne shower gel according to claim 6, characterized in that: The cleansing and anti-acne shower gel comprises, by mass, 1-5 parts of the cleansing and anti-acne composition according to any one of claims 1 to 4, 10-30 parts of a surfactant, 5-10 parts of a moisturizer, 1-5 parts of a skin conditioner, and 50-85 parts of a solvent.
8. The cleansing and anti-acne shower gel according to claim 6 or 7, characterized in that: The surfactant includes any one or a combination of at least two of sodium laureth sulfate, sodium lauryl sulfate, sodium lauroyl sarcosinate or cocamidopropyl betaine; Preferably, the humectant comprises glycerin and / or sodium PCA; Preferably, the skin conditioning agent comprises any one or a combination of at least two of sodium polyaspartate, butylene glycol, pentylene glycol, hexylene glycol or tocopherol; Preferably, the solvent comprises water.
9. A method for preparing the cleansing and anti-acne shower gel according to any one of claims 6 to 8, characterized in that: The preparation method comprises the following steps: The emulsifier and the moisturizer are mixed and homogenized to obtain a mixed liquid; and then the mixed liquid is mixed and stirred with the cleansing and anti-acne composition, the skin conditioner and the solvent to obtain the cleansing and anti-acne shower gel.
10. The preparation method according to claim 9, characterized in that The mixing and homogenizing speed before obtaining the mixed liquid is 1000-3000 rpm, the mixing and homogenizing temperature is 80-90°C, and the mixing and homogenizing time is 20-40 min; Preferably, the mixing and stirring speed before obtaining the cleansing and anti-acne shower gel is 10-40 rpm, the mixing and stirring temperature is 45-50° C., and the mixing and stirring time is 20-40 min.
Citation Information
Patent Citations
Oil-controlling, moisturizing and acne-removing shower gel and preparation method thereof
CN119499138A