Specimen liquid extractor with quantifying function

Abstract

The invention relates to a specimen liquid extractor with a quantification function, and belongs to the technical field of medical instruments, the specimen liquid extractor comprises a main control module, a suction device, an anti-reflux protection device, a human-computer interaction interface and an extractor shell, the main control module comprises an MCU core controller, a lithium polymer battery and a miniature camera, and the lithium polymer battery supplies power to the MCU core controller and the micro camera. According to the sample liquid extractor, the problem that a traditional sample liquid extractor possibly loses efficacy due to the fact that liquid viscosity is too high or contains impurities when quantitative operation is conducted through a flow sensor is solved, image recognition is not affected by liquid physical characteristics by directly observing the liquid level height, and a better quantitative function is achieved; through image recognition, a probe or other quantitative sensors do not need to be inserted into liquid, the risk of cross contamination can be effectively avoided while automatic quantification is achieved, rapid quantitative and accurate extraction of the sample liquid can be effectively achieved, the risk of contamination in an operation is reduced, and the sterile requirement of an operating room is met.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, in particular to a specimen liquid extractor with a quantitative function. Background Art

[0002] A specimen fluid extractor is a specialized tool or device used to extract liquid or preservative fluid from biological specimens (such as tissues, cells, body fluids, etc.). This type of equipment is widely used in medicine, biology, laboratory research, and other fields.

[0003] In the operating room, nurses need to frequently collect body fluids (such as blood, pus, peritoneal lavage fluid, etc.) or tissue specimens from patients for rapid intraoperative testing or postoperative pathological analysis. In traditional operations, nurses usually use syringes or manual pipettes to collect samples. During daily use, the following problems exist: 1. Insufficient precision. Manual operation can easily lead to deviations in the extraction volume, affecting the test results; 2. Low efficiency. The volume needs to be calibrated repeatedly, which prolongs the operation time; 3. Contamination risk. It is easy to come into contact with contaminants during the operation, destroying the sterile environment.

[0004] To solve the above problems, a specimen liquid extractor with a quantitative function is proposed. Traditional specimen liquid extractors perform quantitative operations through flow sensors, which may fail due to high liquid viscosity or impurities. Image recognition directly observes the liquid level and is not affected by the physical properties of the liquid. It has better quantitative function. Moreover, through image recognition, there is no need to insert a probe into the liquid or use other quantitative sensors. While achieving automatic quantification, it can effectively avoid the risk of cross-contamination. It can effectively realize rapid, quantitative and accurate extraction of specimen fluid, reduce the risk of intraoperative contamination, meet the sterile requirements of the operating room, simplify the operating process, improve the work efficiency of nurses, and can be adapted to various specimen types such as blood, tissue fluid, and flushing fluid, with good applicability. Summary of the Invention

[0005] The present invention provides a specimen fluid extractor with a quantitative function, which solves the problems of low efficiency, large errors and infection risks of traditional tools. It can quickly and accurately extract and preserve patient body fluid or tissue fluid samples during surgery, simplify the operating process, and improve nurses' work efficiency.

[0006] The present invention solves the above-mentioned technical problems as follows: A specimen liquid extractor with a quantitative function comprises a main control module, a suction device, an anti-backflow protection device, a human-computer interaction interface, and an extractor housing, wherein the main control module comprises an MCU core controller, a lithium polymer battery, and a micro camera, wherein the lithium polymer battery powers the MCU core controller and the micro camera, the micro camera is provided with a GPIO or UART communication interface, the MCU core controller is signal-connected to the micro camera, the micro camera transmits liquid level video information to the MCU core controller, the MCU core controller is provided with a quantitative monitoring module, and the quantitative monitoring module realizes image recognition and quantitative monitoring through image preprocessing, liquid level detection algorithm, and liquid level determination in sequence, and the lithium polymer battery powers the suction device and the human-computer interaction interface;

[0007] The suction device includes a micro vacuum pump, a proportional valve, a one-way air valve, a flow detector, a main suction pipe, a liquid pipe, and a liquid storage bottle;

[0008] The anti-backflow protection device includes a one-way valve and an isolation head. The one-way valve is installed in the gap between the pipette and the liquid storage bottle. The isolation head is threadedly connected to the main air extraction pipe. The one-way valve can effectively prevent the sample from flowing back.

[0009] The human-computer interaction interface includes a touch screen, and the touch screen is connected to the MCU core controller signal.

[0010] On the basis of the above technical solution, the present invention can also be improved as follows.

[0011] Furthermore, the micro vacuum pump, proportional valve, one-way air valve, flow detector, and main exhaust pipe are connected in sequence. The speed of the micro vacuum pump is controlled by a PWM signal, and the proportional valve can adjust the negative pressure range from -50kPa to -100kPa.

[0012] Furthermore, the liquid storage bottle is made of a transparent material and has scale lines on its surface. The pipette is connected to the liquid storage bottle and can collect the specimen liquid into the liquid storage bottle.

[0013] Furthermore, the isolation head is equipped with a physical isolation membrane and a hydrophobic breathable membrane. The physical isolation membrane is a polytetrafluoroethylene microporous filter membrane, and the hydrophobic breathable membrane is an expanded polytetrafluoroethylene membrane. The polytetrafluoroethylene microporous filter membrane has a pore size of 0.22 μm, which can effectively resist chemical corrosion and prevent bacteria, cell debris, etc. from flowing back into the equipment pipeline. The expanded polytetrafluoroethylene membrane can prevent liquid water or solution from entering the equipment pipeline, thereby preventing the specimen fluid from contaminating the extractor.

[0014] Furthermore, the touch screen displays the extraction volume, negative pressure value and operation status in real time, and the MCU core controller is configured with a one-button start / pause start-stop controller to adapt to emergency scenarios during surgery.

[0015] Furthermore, the MCU core controller signal is connected to a buzzer and an LED indicator light, which can be used to indicate the status and indicate when the process is started or completed.

[0016] Furthermore, the micro camera is equipped with a ring-shaped white LED fill light to ensure uniform reflection on the liquid surface.

[0017] Furthermore, the specific steps of the quantitative monitoring module to implement image recognition quantitative monitoring are as follows:

[0018] S1, image preprocessing, a. Eliminate lens distortion using camera calibration parameters, including the intrinsic parameter matrix and distortion coefficient plate; b. Define the scale area of ​​the liquid storage bottle as the region of interest (ROI) to reduce the amount of calculation; c. Use contrast-limited adaptive histogram equalization to eliminate reflection interference;

[0019] S2, liquid level detection algorithm, a. Edge detection, Canny operator extracts the liquid surface edge; b. Edge detection, Canny operator extracts the liquid surface edge; c. Coordinate mapping, converting the liquid surface position into volume value according to the preset bottle body scale-pixel correspondence table;

[0020] S3, liquid level determination, a, calibration liquid level setting, the nurse inputs the target volume through the touch screen, and the system calculates the corresponding liquid level pixel position Y according to the bottle diameter-height relationship. target ; b. Real-time judgment

[0021]

[0022] ΔY target The tolerance threshold is usually 2-3 pixels, corresponding to a 0.1 mL error.

[0023] The beneficial effects of the present invention are as follows: the present invention provides a specimen liquid extractor with a quantitative function, which has the following advantages:

[0024] 1. The traditional specimen liquid extractor uses a flow sensor for quantitative operation, which may fail due to high liquid viscosity or impurities. Image recognition directly observes the liquid level and is not affected by the physical properties of the liquid, thus having better quantitative function.

[0025] 2. Through image recognition, there is no need to insert a probe into the liquid or use other quantitative sensors. Automatic quantification can be achieved while effectively avoiding the risk of cross contamination. It can effectively achieve rapid, quantitative and accurate extraction of specimen liquid, reduce the risk of intraoperative contamination, and meet the sterility requirements of the operating room;

[0026] 3. Such a specimen fluid extractor has a simple operation process, can effectively improve the work efficiency of nurses, can be adapted to various specimen types such as blood, tissue fluid, flushing fluid, etc., and has good applicability.

[0027] The above description is only an overview of the technical solution of the present invention. In order to more clearly understand the technical means of the present invention and to implement it according to the contents of the description, the following preferred embodiments of the present invention are described in detail with reference to the accompanying drawings. The specific implementation methods of the present invention are given in detail by the following embodiments and the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] The drawings described herein are used to provide a further understanding of the present invention and constitute a part of this application. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation of the present invention. In the drawings:

[0029] Figure 1 A schematic structural diagram of a specimen liquid extractor with a quantitative function provided by one embodiment of the present invention;

[0030] Figure 2 A front view of a specimen liquid extractor with a quantitative function provided by one embodiment of the present invention;

[0031] Figure 3 A schematic structural diagram of the connection state of the isolation head of a specimen liquid extractor with a quantitative function provided by one embodiment of the present invention;

[0032] Figure 4 A schematic structural diagram of a specimen liquid extractor with a quantitative function in a disassembled state of an isolation head provided by one embodiment of the present invention;

[0033] Figure 5 This is a schematic structural diagram of a touch screen in a specimen liquid extractor with a quantitative function provided by one embodiment of the present invention.

[0034] In the accompanying drawings, the components represented by the reference numerals are as follows:

[0035] 1. MCU core controller; 2. Lithium polymer battery; 3. Miniature vacuum pump; 4. Proportional valve; 5. Pipette; 6. Liquid storage bottle; 7. One-way valve; 8. Isolation head; 9. Physical isolation membrane; 10. Hydrophobic breathable membrane; 11. Touch screen; 12. One-way air valve; 13. Flow detector; 14. Main exhaust pipe; 15. Buzzer; 16. LED indicator; 17. Miniature camera; 18. Ring-shaped white LED fill light; 19. Extractor housing; 20. Start-stop controller. DETAILED DESCRIPTION

[0036] The following is combined with Figure 1-5The principles and features of the present invention are described, and the examples given are only for the purpose of explaining the present invention and are not intended to limit the scope of the present invention. The following paragraphs describe the present invention in more detail by way of example with reference to the accompanying drawings. The advantages and features of the present invention will become more apparent from the following description and claims. It should be noted that the drawings are in a very simplified form and are not in exact proportions, and are only used for the purpose of conveniently and clearly assisting in illustrating the embodiments of the present invention.

[0037] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which this invention pertains. The terms used in this specification of the present invention are for the purpose of describing specific embodiments only and are not intended to limit the present invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0038] like Figure 1-2 As shown, the present invention provides a specimen liquid extractor with a quantitative function, including a main control module, a suction device, an anti-backflow protection device, a human-computer interaction interface, and an extractor housing 19. The main control module includes an MCU core controller 1, a lithium polymer battery 2, and a micro camera 17. The lithium polymer battery 2 supplies power to the MCU core controller 1 and the micro camera 17. The micro camera 17 is provided with a GPIO or UART communication interface. The MCU core controller 1 is connected to the micro camera 17 by signal. The micro camera 17 transmits liquid level video information to the MCU core controller 1. The MCU core controller 1 is provided with a quantitative monitoring module. The quantitative monitoring module is sequentially processed by image pre-processing. The liquid level detection algorithm and liquid level determination realize image recognition quantitative monitoring. The lithium polymer battery 2 supplies power to the suction device and the human-computer interaction interface. The suction device includes a micro vacuum pump 3, a proportional valve 4, a one-way air valve 12, a flow detector 13, a main air extraction pipe 14, a liquid pipette 5, and a liquid storage bottle 6. The anti-backflow protection device includes a one-way valve 7 and an isolation head 8. The one-way valve 7 is mounted in the gap between the liquid pipette 5 and the liquid storage bottle 6. The isolation head 8 is threadedly connected to the main air extraction pipe 14. The one-way valve 7 can effectively prevent the sample from flowing back. The MCU core controller 1 is signal-connected to a buzzer 15 and an LED indicator 16. The buzzer 15 and the LED indicator 16 can be used to indicate the status and indicate when starting and completing.

[0039] The micro camera 17 is equipped with a ring-shaped white LED fill light 18 to ensure uniform reflection of the liquid surface;

[0040] The micro vacuum pump 3, the proportional valve 4, the one-way air valve 12, the flow detector 13, and the main exhaust pipe 14 are connected in sequence. The speed of the micro vacuum pump 3 is controlled by a PWM signal, and the proportional valve 4 can adjust the negative pressure range from -50kPa to -100kPa.

[0041] like Figure 5 As shown, the human-computer interaction interface includes a touch screen 11, which is signal-connected to the MCU core controller 1. The touch screen 11 displays the extraction volume, negative pressure value and operation status in real time. The MCU core controller 1 is equipped with a one-button start / pause start-stop controller 20 to adapt to emergency scenarios during surgery.

[0042] like Figure 3-4 As shown, the liquid storage bottle 6 is made of transparent material and has scale lines on the surface. The pipette 5 is connected to the liquid storage bottle 6, and the pipette 5 can collect the specimen liquid into the liquid storage bottle 6; the isolation head 8 is installed with a physical isolation membrane 9 and a hydrophobic breathable membrane 10. The physical isolation membrane 9 is a polytetrafluoroethylene microporous filter membrane, and the hydrophobic breathable membrane 10 is an expanded polytetrafluoroethylene membrane. The pore size of the polytetrafluoroethylene microporous filter membrane is 0.22μm, which can effectively resist chemical corrosion and prevent bacteria, cell debris, etc. from flowing back into the equipment pipeline. The expanded polytetrafluoroethylene membrane can prevent liquid water or solution from entering the equipment pipeline, thereby preventing the specimen liquid from contaminating the extractor.

[0043] The preferred embodiments of the present invention are:

[0044] Collection of mixed pus and irrigating fluid samples during appendectomy

[0045] S1, assemble the specimen liquid extractor, use a 3mm pipette 5 with an anti-clogging tip to connect to a 30mm volume liquid storage bottle 6, install a one-way valve 7 on the pipette 5 and then connect it to the liquid storage bottle 6, install the isolation head 8 on the main exhaust pipe 14, the physical isolation membrane (9) and the hydrophobic breathable membrane (10) in the isolation head 8 can intercept the specimen liquid and bacteria and cell debris to prevent them from contaminating the extractor;

[0046] S2, set the quantitative target, preset the negative pressure of the micro vacuum pump 3 to -80kPa on the touch screen 11, and the quantitative target liquid level to 20mm;

[0047] S3, specimen liquid extraction, keep the extractor housing 19 horizontal to ensure that the liquid level in the liquid storage bottle 6 remains level, start the micro vacuum pump 3 through the start-stop controller 20 to perform vacuum extraction, and the specimen liquid can be pumped into the liquid storage bottle 6 through the pipette 5. The micro camera 17 can detect the liquid level in real time. When the quantitative target is reached, the MCU core controller 1 controls the micro vacuum pump 3 to stop, the buzzer 15 sounds a buzzer, and the LED indicator 16 flashes green to indicate;

[0048] S4, sample transfer, remove the liquid storage bottle 6 from the isolation head 8, remove the pipette 5, seal the liquid storage bottle 6 with the cover, and send it to the laboratory;

[0049] S5, equipment cleaning, clean the isolation head 8 by wiping it with alcohol cotton, and then replace the next disposable component according to actual needs.

[0050] It should be noted that, in this document, relational terms such as first and second are used solely to distinguish one entity or operation from another, and do not necessarily require or imply any actual relationship or order between these entities or operations. Matters not described in detail in this specification are well known to those skilled in the art.

[0051] The above description is only a preferred embodiment of the present invention and does not limit the present invention in any form. Any ordinary technician in this industry can smoothly implement the present invention as shown in the drawings and described above. However, any equivalent changes, modifications and evolutions made by technicians familiar with this profession without departing from the scope of the technical solution of the present invention using the technical content disclosed above are all equivalent embodiments of the present invention. At the same time, any equivalent changes, modifications and evolutions made to the above embodiments based on the essential technology of the present invention are still within the scope of protection of the technical solution of the present invention.

Claims

1. A specimen liquid extractor with a quantitative function, comprising a main control module, a suction device, an anti-backflow protection device, a human-machine interface, and an extractor housing (19), characterized in that: The main control module comprises an MCU core controller (1), a lithium polymer battery (2), and a micro camera (17); the lithium polymer battery (2) supplies power to the MCU core controller (1) and the micro camera (17); the micro camera (17) is provided with a GPIO or UART communication interface; the MCU core controller (1) is signal-connected to the micro camera (17); the micro camera (17) transmits liquid level video information to the MCU core controller (1); the MCU core controller (1) is provided with a quantitative monitoring module; the quantitative monitoring module sequentially implements image recognition quantitative monitoring through image preprocessing, liquid level detection algorithm, and liquid level determination; the lithium polymer battery (2) supplies power to the suction device and the human-computer interaction interface; The suction device comprises a micro vacuum pump (3), a proportional valve (4), a one-way air valve (12), a flow detector (13), a main air extraction pipe (14), a liquid pipette (5), and a liquid storage bottle (6); The anti-backflow protection device comprises a one-way valve (7) and an isolation head (8), wherein the one-way valve (7) is mounted at the gap between the liquid pipe (5) and the liquid storage bottle (6), and the isolation head (8) is threadedly connected to the main air extraction pipe (14); The human-computer interaction interface comprises a touch screen (11), and the touch screen (11) is signal-connected to the MCU core controller (1).

2. The specimen liquid extractor with quantitative function according to claim 1, characterized in that: The micro vacuum pump (3), proportional valve (4), one-way air valve (12), flow detector (13), and main air extraction pipe (14) are connected in sequence.

3. The specimen liquid extractor with quantitative function according to claim 1, characterized in that: The liquid storage bottle (6) is made of a transparent material and has scale lines on its surface. The pipette (5) is in communication with the liquid storage bottle (6).

4. The specimen liquid extractor with quantitative function according to claim 1, characterized in that: The isolation head (8) is equipped with a physical isolation membrane (9) and a hydrophobic breathable membrane (10), wherein the physical isolation membrane (9) is a polytetrafluoroethylene microporous filter membrane, and the hydrophobic breathable membrane (10) is an expanded polytetrafluoroethylene membrane.

5. The specimen liquid extractor with quantitative function according to claim 1, characterized in that: The touch screen (11) displays the extraction volume, negative pressure value and operation status in real time, and the MCU core controller (1) is equipped with a start-stop controller (20).

6. The specimen liquid extractor with quantitative function according to claim 1, characterized in that: The MCU core controller (1) is signal-connected to a buzzer (15) and an LED indicator light (16).

7. The specimen liquid extractor with quantitative function according to claim 1, characterized in that: The miniature camera (17) is equipped with a ring-shaped white LED fill light (18).

8. The specimen liquid extractor with quantitative function according to claim 1, characterized in that: The specific steps of implementing image recognition quantitative monitoring by the quantitative monitoring module are as follows: S1, image preprocessing, a. Eliminate lens distortion using camera calibration parameters, including the intrinsic parameter matrix and distortion coefficient plate; b. Define the scale area of ​​the liquid storage bottle as the region of interest (ROI) to reduce the amount of calculation; c. Use contrast-limited adaptive histogram equalization to eliminate reflection interference; S2, liquid level detection algorithm, a. Edge detection, Canny operator extracts the liquid surface edge; b. Edge detection, Canny operator extracts the liquid surface edge; c. Coordinate mapping, converting the liquid surface position into volume value according to the preset bottle body scale-pixel correspondence table; S3, liquid level determination, a, calibration liquid level setting, the nurse inputs the target volume through the touch screen, and the system calculates the corresponding liquid level pixel position Y according to the bottle diameter-height relationship. target ; b. Real-time judgment ΔY target The tolerance threshold is usually 2-3 pixels, corresponding to a 0.1 mL error.

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